Journal of Pharmacology and Experimental Therapeutics

Article	Citations
SAR340835, a Novel Selective Na+/Ca2+ Exchanger Inhibitor, Improves Cardiac Function and Restores Sympathovagal Balance in Heart Failure	158
In Vitro Assessment of the Drug–Drug Interaction Potential of Verinurad and Its Metabolites as Substrates and Inhibitors of Metabolizing Enzymes and Drug Transporters	56
Myocardial SERCA2 Protects Against Cardiac Damage and Dysfunction Caused by Inhaled Bromine	50
Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells	46
pH Dependence of a GPR4 Selective Antagonist Hampers Its Therapeutic Potential	38
Identification and Characterization of ACP-5862, the Major Circulating Active Metabolite of Acalabrutinib: Both Are Potent and Selective Covalent Bruton Tyrosine Kinase Inhibitors	38
Agent-Based Modelling Reveals the Role of the Tumor Microenvironment on the Short-Term Success of Combination Temozolomide/Immune Checkpoint Blockade to Treat Glioblastoma	36
Modulation of the Immune Response to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination by Nonsteroidal Anti-Inflammatory Drugs	33
An Integrative Approach to Elucidate Mechanisms Underlying the Pharmacokinetic Goldenseal-Midazolam Interaction: Application of In Vitro Assays and Physiologically Based Pharmacokinetic Models to Unde	32
An Integrative Approach for Improved Assessment of Cardiovascular Safety Data	30
A Novel Integrated Pharmacokinetic-Pharmacodynamic Model to Evaluate Combination Therapy and Determine In Vivo Synergism	27
Special section on Breaking Barriers in Women's Cancer Treatment: Innovative Approaches and Experimental Therapeutics—Editorial	25
Quantitative Systems Pharmacology and Machine Learning: A Match Made in Heaven or Hell?	25
Generation and Characterization of Mirikizumab, a Humanized Monoclonal Antibody Targeting the p19 Subunit of IL-23	25
Mechanisms and management of thrombosis in cancer: Focus on gastrointestinal malignancies	23
Evidence for cytoprotective autophagy in response to HER2-targeted monoclonal antibodies	22
CNOT6L deadenylase suppresses cardiac remodeling in heart failure through downregulation of tenascin-C mRNA	21
Competitive Interactions Between Propofol and Diazepam: Studies in GABAA Receptors and Zebrafish	20
Editorial Board	20
Managing Iron Overload: A Gut Check	20
Beclin-1–Derived Peptide MP1 Attenuates Renal Fibrosis by Inhibiting the Wnt/β-Catenin Pathway	19
Metabolic Rewiring and Mechanism of Action of an Antiepileptic Drug Repurposed for its Potential in Glioblastoma	19
Nucleotidases Exhibit Enzymatic Activities Toward the Pharmacologically Active Metabolites of Gemcitabine and Emtricitabine	19
The Evolving Challenge of New Psychoactive Substances: Understanding the Risks and Behavioral Effects of Novel Analogs of Dissociative Anesthetics	19
Calcium-dependent regulation of G protein-coupled receptor kinases	19

Comprehensive analysis of CYP2D6 mutations in human cancers	19
Biased Allosteric Modulation of β2-adrenergic Receptor Signaling and Bronchodilation by different β-agonists	19
SERCA Inhibition by Drugs - A Potential Therapeutic Strategy in Ischemia	19
Table of Contents	19
Beta-hydroxyphosphocarnitine modifies the inflammation in rats with non-alcoholic steatohepatitis	18
Ventilatory Effects of Mu Opioid Receptor Agonist Mixtures	18
Differential effects of kappa opioid receptor activation and blockade on the development of methamphetamine-induced sensitization in adult male and female rats	18
Location Biased G Protein-Coupled Receptor Signaling Modulates Distinct Spatial Conformations of β-arrestins	17
A novel UVA-labile β-adrenergic agonist allows for optical control of subcellular signaling	17
Therapeutic Assessment of Combination Therapy with a Neprilysin Inhibitor and Angiotensin Type 1 Receptor Antagonist on Angiotensin II–Induced Atherosclerosis, Abdominal Aortic Aneurysms, and Hyperten	17
Visualization of Region-Specific Lipid Alterations in the Mouse Brain in Response to Efavirenz Treatment Using MALDI Mass Spectrometry Imaging	17
Characterizing a Mesolimbic Circuit for Opioid Reward	17
Discovery of RNA Editing Inhibitors for Neurological Disorders	16
Disrupting the interaction between constitutively active Gαq and Gβγ inhibits oncogenic signaling	16
Enzyme Kinetics of Benzalkonium Chloride Metabolism in Liver Microsomes	16
Effects of Cannabinoid Agonists on Fentanyl-Induced Respiratory Depression	16
Assessment of an Allosteric Modulator of GIRK 1/2 in Preclinical Models of Cancer-Related Neuropathies to Alleviate Associated Mechanical Allodynia	16
The Red Algae Jania rubens Sensitizes Colon Cancer Cells to Doxorubicin Chemotherapy	16
Identifying and Testing Novel Sigma-1 Receptor Ligands for Neurodegenerative Diseases.	16
Redox Partner Adrenodoxin Allosterically Alters the Function of the Human Steroidogenic Cytochrome P450 11B Enzymes	16
Pharmacologic and Endotoxic Reprogramming of Renal Vasodilatory, Inflammatory, and Apoptotic Blemishes in Weaning Preeclamptic Dams	16
Brilaroxazine Displays Limited Interaction with Clinically Relevant Drug Transporters	16
Redox Partner Adrenodoxin Allosterically Alters the Function of the Human Steroidogenic Cytochrome P450 11B Enzymes	14
Neurostimulation of the renal nerves as a novel therapeutic option for obstructive sleep apnea treatment	14
Filming the DNA Damaging Mechanisms of AuNP by the Four Dimensions Atomic Force Microscopy (4DAFM) in Molecular Environment	14
Mechanistic Insights into Xanthohumol-Induced Apoptosis and Cytokine Modulation in Multiple Myeloma with a Focus on Nanoparticle Targeting Strategies	14
Molecular Dynamics Studies for Nirmatrelvir and the Main Protease from Variants of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)	14
Examining the DNA Methylation Profile of Childhood Solid Tumors to Identify Novel Therapeutically Targeted Sites	14
miR-146a; a potential link connecting shear stress-induced activation of the pro-inflammatory and pro-proliferative Osteopontin & TLR-4 pathways	14
Interactions between Biological Sex and Hormonal Cycles in Stimulant Effects on Motor Behavior	14
Investigating Birch Bark Oil Anti-Oxidative Properties in Human Keratinocytes	14
Role of β-arrestin-2 in the development of opioid withdrawal in the mouse colon	13
Can Generative Artificial Intelligence (AI) Reliably Score Open-Ended Questions (OEQs) in the Assessment of Medical Knowledge	13
Membrane Raft Redox Signalling Pathway in Nicotine-Induced NLRP3 Inflammasome Activation and Podocyte Injury	13
Activation of PTH1 receptor using chimeric peptide templated in situ click reaction of nanobody conjugates	13
Enhancing the Scalability and Therapeutic Window of Taccalonolide-based Chemotherapeutics for the Treatment of Triple-negative Breast Cancers	13
Structural Dynamics in RhoGEF Signaling Investigated Using Model Cell Membranes	13
Effects of a highly G Protein-Biased Mu Opioid Receptor Agonist, SR-17018, in Non-human Primates	13
Beta2-Adrenergic receptor agonism as a therapeutic strategy for the treatment of Cushing’s syndrome	13
The BDFN-TrkB-KCC2 pathway as a potential treatment target for modulating alcohol consumption	13
Molnupiravir Metabolite--N4-Hydroxycytidine Causes DNA Damage in Hepatoblastoma Cells and Lung Large Cell Carcinoma Cells in Vitro	13
A Treatment to Eliminate Respiratory Viral Infections Associated with Asthma Exacerbations	13
Dopamine D1-Like Receptor-Mediated Insurmountable Blockade of the Reinforcing Effects of Cocaine in Rats	13
Structure-activity relationship of G protein-coupled receptor kinase 5 (GRK5) and its mutants	12
Blockade of selective Gβγ signaling pathway by gallein decreases development of opioid tolerance	12
Behavioral and Neurochemical Effects of Extended Access to Stimulant Self-Administration in Rats	12
Phenylacetylglutamine causes a pathologic inflammation state through the ß2-adrenergic receptor /cAMP/PKA/NF-κB pathway in diabetes	12
An Elastin-like Polypeptide-fused Peptide Inhibits MMP-2 Activity at nM Concentrations with High Specificity	12
Changes of ACE-2 related-miR-200b-3p expression over time are a predictive factor of long hospitalization for COVID-19: in silico, machine learning and validation analysis	12
Molecular Investigation of the Ameliorative Potentials of Cymbopogon citratus Leaves Extract in Carbon tetrachloride- Induced Hepatotoxicity in rats	12

β-adrenoceptor-mediated vasodilation is enhanced by acute colchicine-treatment in men with essential hypertension	12
Agonist concentration-dependent conformational changes of formyl peptide receptor 1 contribute to biased signaling in phagocytes	12
Structure, Function, and Pharmacology of Delta Opioid Receptor Bitopics	12
Calcium Channel Blockers as Novel Therapeutic Agents for Triple-Negative Breast Cancer	11
Student perceptions of scholarly scientific writing in pharmacology: student generation of collaborative rubrics to score literature reviews in social pharmacology	11
Investigating Tucatinib Metabolism and CYP3A and CYP2C8 Phenotypes in Human Liver Microsomes from African Americans in vitro	11
Ixazomib Induces Apoptosis and Suppresses Proliferation in Esophageal Squamous Cell Carcinoma through Activation of the c-Myc/NOXA Pathway	11
Anisodamine Enhances Macrophage M2 Polarization through Suppressing G9a-Mediated Interferon Regulatory Factor 4 Silencing to Alleviate Lipopolysaccharide-Induced Acute Lung Injury	11
Development of a Cytochrome P450 CYP3A7 Quantitative Structure-Inhibitory Relationship (QSIR) Model to Assess Drug Safety in Neonates	11
Amlodipine use in Mild Cognitive Impairment reduces the risk of incident dementia in National Alzheimer’s Coordinating Center participants aged ≥55 years from 2014-2019	11
Complexity in Hepatic Insulin Resistance – Unraveling the Role of Ubiquitin-Specific Protease 14 in Protein Homeostasis of Metabolic Transcription Factors	11
Editorial Board	11
Effects of Volatile Anesthetics versus Ketamine on Blood-Brain Barrier Permeability via Lipid-Mediated Alterations of Endothelial Cell Membranes	11
Histone Deacetylase Inhibitor Belinostat Regulates Metabolic Reprogramming in Killing Kras-Mutant Human Lung Cancer Cells	11
Methocinnamox is a Potent and Long-Acting Antagonist that can Prevent and Reverse Opioid-Induced Respiratory Depression	11
Cyclin-dependent kinase 4/6 Inhibitor Abemaciclib and Histone deacetylase Inhibitor Panobinostat Treatment Exerts Metabolic Reprogramming of Pancreatic Cancer Cells	11
Implementation of Supplemental Small-Group Sessions in an Online Clinical Pharmacology Course	11
Effect of Novel Biotherapeutic Elevating Angiopoietin 1 on Progression of Diabetic Nephropathy in Diabetic/Obese Mice	11
Big Benefits from Linking Small Antibodies (Nanobodies) to Small Molecule GPCR Ligands	11
Presynaptic Regulation of Monoamine Release in the Dorsal Raphe Nucleus by Alpha2-adrenergic Receptors	10
The Buprenorphine Analogue BU10119 Attenuates Drug-Primed and Stress-Induced Cocaine Reinstatement in Mice	10
RNA-Mediated Regulation of Concentrative Nucleoside Transporter 3	10
The National Center for Complementary and Integrative Health: Priorities for Cannabis and Cannabinoid Research	10
GPR55 Antagonist KLS-13019 Prevents and Reverses Chemotherapy-Induced Peripheral Neuropathy (CIPN) in Rats	10
Impaired Nitric Oxide-Dependent Vasorelaxation in Metabolic Syndrome	10
2-Substituted (N)-Methanocarba A3 Adenosine Receptor Agonists: In silico, in vitro and in vivo Characterization	10
TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia	10
Translational Pharmacokinetic/Pharmacodynamic Modeling of Targeted mRNA-LNP Therapeutics	10
High SNP concentrations on the X-chromosome suggest prospective gene targets FTX, CROCCP1, TTC3P1, KANTR, and AP2B1P in medulloblastoma	10
Modulation of Angiotensin II-Induced Cellular Hypertrophy by Cannflavin-C: Unveiling the Impact on Cytochrome P450s 1B1 and Arachidonic Acid Metabolites	10
Angiotensin-(1-7) and Gut-Bone Marrow Axis in Aging	10
Multitarget-Directed Ligands with Soluble Epoxide Hydrolase and Fatty Acid Amide Hydrolase Inhibitory Activities for Treatment of Chronic Pain	10
Development of N-acyl Fluspirilene 20S Proteasome Enhancers for the Treatment of Neurodegenerative Diseases	10
Differential Susceptibilities of Catecholamines to Metabolism by Monoamine Oxidases	10
The Intoxication Equivalency of 11-Hydroxy-Δ9-Tetrahydrocannabinol Relative to Δ9-Tetrahydrocannabinol	10
Investigating Mu-Opioid Receptor Selectivity of Potentiation of Antinociceptive Effects by a Gβγ Inhibitor, Gallein	10
Characterization of OJT008 As a Novel Inhibitor of Mycobacterium tuberculosis	10
SS-31 Attenuates Doxorubicin-induced Cardiomyoblast H9C2 Cell Senescence	10
Integration and Alignment of Pharmacological Principles and Agents in a Preclinical Problem-Based Learning Curriculum Through a Web-Based Interface	9
Brazilian Green Propolis-Based Nanostructured System and its use in diabetic rats of Staphylococcus aureus resistant to methicillin (MRSA)-infected wounds	9
Pharmacological Modulation of Hsp70 to Selectively Remove Misfolded Neuronal Nitric Oxide Synthase	9
Transport Inhibitors to enhance central and peripheral nervous system antidote activity to organophosphate (OP) exposure	9
A High Throughput Cell-Based Deubiquitinase Screening Assay	9
Platycodon Grandifloras Reduces Weight Gain and Attenuates Hepatic Steatosis in a Diet-Induced Mouse Model of Obesity	9
Targeting Adenylyl Cyclase Type 8, Orai1, and Stromal Interaction Molecule 1 in Triple-Negative Breast Cancer	9
Probing Adropin-Gpr19 Interactions and Signal Transduction	9
Classical Activation of HMC3 Human Brain Microglia by Cyanobacterium Brasilonema sp LPS: Interleukin-6 and Interferon-γ Production	9
Diversity, Equity, and Inclusive Course Design in Pharmacology Education: Strategies, Opportunities and Lessons Learned	9
Effect of Topical Application of cannabis fixed Oil on Imiquimod-Induced Psoriasis-like Lesions in the Thin Skin of Adult Male Albino rabbits	9
The hepatocyte estrogen sulfotransferase dictates female sensitivity to T cell-mediated hepatitis independent of estrogens	9
Targeting the TAK1/TNF signaling pathway with novel pharmacological inhibitors	9
A positive allosteric modulator of M1 Acetylcholine receptors improves cognitive deficits in male and female APPswe/PSEN1ΔE9 mice via divergent mechanisms	9
Professional Pharmacology and Pharmacy Organization Responses to the Dobbs v. Jackson Supreme Court Ruling	9
Deferiprone Decreases Labile Iron in Brain and Ameliorates Abnormal Emotional Behavior in Mice with Brain Iron Accumulation	9
A Behavioral Economic Analysis of Polysubstance Use: Studies with Cocaine, Fentanyl, and Cocaine–Fentanyl Mixtures in Sprague-Dawley Rats	9
Long-term Neurochemical Effects of Adolescent Nicotine Self-administration on Dopamine Dynamics in the Nucleus Accumbens Core	9
Downregulation in Connexin43 expression is associated with reduced ferroptosis and enhanced tolerance to myocardial ischemia-reperfusion injury in type 1 diabetic mice	9
Cocaine Regulates Antiretroviral Therapy CNS Access Through Pregnane-X Receptor-Mediated Drug Transporter and Metabolizing Enzyme Modulation at the Blood Brain Barrier	9
Calcium Imaging Alongside Deep Behavior Learning in Fentanyl Vapor Self-Administration	9
IRX4204 enhances gait recovery in mice subjected to experimental autoimmune encephalomyelitis	8
Development of a Physiologically Based Pharmacokinetic Model for Predicting Midazolam Pharmacokinetics in a Pediatric Population with Obesity	8
The Adhesion GPCR GPR114/ADGRG5 is Activated by its Tethered-Peptide-Agonist Following Receptor Fragment Dissociation	8
Acute and Subchronic GPR171 Agonism Affects Anxiety and Depression in Female Mice	8
Paradoxical Effect of Nitric Oxide on GRK2 in the Kidney and Heart: Implications for Sepsis-Associated Kidney Injury	8
Podocyte injury triggers the formation of intercellular bridges	8
Tubulin acetylation attenuates vasorelaxation in a smooth muscle-dependent manner and contributes to hypertension	8
Synthesis and Structure-Activity Relationship of SAE-14 Analogs as G-Protein Coupled Receptor 183 Antagonists	8
Screening of plant extracts in achieving novel strategy in promoting efficacy and combat Cisplatin-induced neurotoxicity	8
Elucidating the role of ubiquitination of insulin signaling molecules in HepG2 cells insulin resistance model	8
First potent macrocyclic A3 adenosine receptor agonists reveal G-protein and beta-arrestin2 signaling preferences	8
The HMGB1/MAPKs/Nrf2 Signaling Arbitrates Hepatoprotection Conferred by Celecoxib in Preeclamptic Weaning Rats	8
Development and Characterization of Third Generation MDM2 PROTACs for the Treatment of Acute Myeloid Leukemia Utilizing an Achiral Ligand for E3 Ligase Cereblon	8
cFos Expression in the Forebrain Following Central Administration of Nociceptin in Heart Failure	8
Faculty Perspective on Implementing a Question-Writing Activity in Physician Assistant Pharmacology Courses	8
Sprague Dawley Rats from Different Vendors Vary in the Modulation of Prepulse Inhibition of Startle (PPI) by Dopamine, Acetylcholine, and Glutamate Drugs	8
Regulated Trafficking of GABA Transporters, GAT1 and GAT3, in Response to Methamphetamine	8
Vaporizing Adolescence: Determining the Neurobiological Consequences of Adolescent Vaping on the Prefrontal Cortex, Nucleus Accumbens, and Ventral Tegmental Area	8
Discovery of Developmental Windows of Drug Sensitivity Using High Content Screening of Normal and Pgp-Knockout Sea Urchin Embryos	8
Protective Effects of Ozanimod in Cisplatin-induced Neuropathic Pain in Mice: Insights from Single-cell Transcriptomic Profiling in Spinal Cord Tissues	7
Defining the landscape of cancer vulnerabilities that are engendered by germline genetic variation	7

Cholesterol Enrichment Alters Compartmentalization of G-Proteins Into Lipid Raft Microdomains	7
Novel compounds that target epoxyeicosanoids protect rat kidney epithelial cells in organ transplant solution during cold storage	7
Impact of RGS10 on Microglial Cell Migration and Proliferation	7
Serendipitous Discovery of Novel 5-HT2AR Positive Allosteric Modulators (PAMs) Derived From 5-HT2CR PAM Scaffolds	7
Development and Characterization of a Cytochrome P450 CYP3A7 Fetal Hepatocyte-Like Cell Model Derived from Induced Pluripotent Stem Cells	7
Biomarkers of Exposure in Human Proximal Tubular Cells Incubated with Nephrotoxic Environmental Chemicals and Drugs: Altered Metabolic Pathways	7
Quantitative Proteomics of Human Urine-Isolated Extracellular Vesicles Reveals Significant and Reproducible Enrichment of EV Markers and Renal Drug-Interacting Proteins	7
Sexual Dimorphism of the Fasting Adipose: Mitigation of Metabolic and Cardiovascular Dysfunction in a Non-Obese Prediabetic Rat Model	7
Inhibition of soluble epoxide hydrolase attenuates high-sucrose diet-mediated gut barrier dysfunction	7
Inhibiting the Cytotoxic Effect of Tubulin Polymerization-Promoting Protein (TPPP/p25α) Induced α-synuclein Aggregates Via 20S Proteasome Enhancement	7
Low-Dose Propofol and Salvianolic Acid a Combination Attenuates Myocardial Ischemia/reperfusion-injured Mitochondrial Metabolism via AMPK/HDAC6 Pathway in Diabetes	7
Elucidating the Disposition and Metabolism of Benzalkonium Chloride compounds in C57BL/6 mice	7
β-Arrestin Isoform Conformations are Location-Biased and affect Downstream Signaling of G-protein Coupled Receptors	7
Development of Transgenic Mouse Platform for the Detection of Endogenous G protein Activity	7
Effect of Inhibition of Xenobiotic Transporter MRP5/ABCC5 on Neurite Elongation: Screening for MRP5 Inhibitors among Clinically Used Drugs	7
Pharmacovigilance of the COVID-19 Vaccine in Ecuador During the First and Second Doses of Vaccination Campaigns	7
The Modulatory Effects of Citrus Flavonoid Hesperetin on Nrf2 Expression and NF-kB Signaling Pathway in LPS-Activated BV-2 Microglial Cells	7
The Effects of Cytokine Receptor Antagonism in the Locus Coeruleus on Stress-related Behaviors in Females	7
Self-Administration of Benzodiazepines in Drug-Naïve Rhesus Monkeys: Role of GABAA Receptor Subtypes	7
A GPT4-based Patient Simulation to Enhance the Integration of Pharmacology with Clinical Decision Making in a PharmD Program	7
Sex Differences in the Behavioral and Metabolic Effects of Prenatal Stress in Early but not Late Adulthood in Mice	7
The Drug Design and Discovery of Novel Enaminone Derivatives as Potential Anti-seizure Agents	7
The Novel, Clinical-Stage Soluble Guanylate Cyclase Activator BI 685509 Protects from Disease Progression in Models of Renal Injury and Disease	6
Antinociceptive and Discriminative Stimulus Effects of Six Novel Psychoactive Opioid Substances in Male Rats	6
Deconstructing the Pharmacological Contribution of Sphingosine-1 Phosphate Receptors to Mouse Models of Multiple Sclerosis Using the Species Selectivity of Ozanimod, a Dual Modulator of Human Sphingos	6
Table of Contents	6
Table of Contents	6
A Comparison of Breathing Stimulants for Reversal of Synthetic Opioid-Induced Respiratory Depression in Conscious Rats	6
Cyclooxygenase Inhibitors and Cancer: The Missing Pieces	6
Response to Comments on “Ocular Pharmacokinetics of Brimonidine Drug Delivery System in Monkeys and Translational Modeling for Selection of Dose and Frequency in Clinical Trials”	6
Development of the first vascular-specific KATP channel inhibitor for the treatment of patent ductus arteriosus in newborns	6
Editorial Board	6
Announcement - Incoming JPET Editor	6
Methyl 2-[3-(4-hydroxyphenyl)prop-2-enoylamino]-3-phenylpropanoate Is a Potent Cell-Permeable Anti-Cytokine Compound To Inhibit Inflammatory Cytokines in Monocyte/Macrophage-Like Cells	6
Editorial Board	6
The Use of Single-Chain Variable Fragments (scFv) to Reverse Cardiopulmonary and Antinociceptive Effects of Fentanyl in Male Mice	6
Effects of Dopamine D1-Like Receptor Ligands on Food-Cocaine Choice in Socially Housed Male Cynomolgus Monkeys	6
Editorial Board	6
β-Arrestins Mediate Rapid 5-HT2A Receptor Endocytosis to Control the Efficacy and Kinetics of Serotonin and Psychedelic Hallucinogen Signaling	6
Enhancing Target Tissue Levels and Diminishing Plasma Clearance of Ionizing Zwitterionic Antidotes in Organophosphate Exposures	6
Contents	6
Anesthetic Preconditioning of Traumatic Brain Injury Is Ineffective in a Drosophila Model of Obesity	6
Preclinical Evaluation of the Effects of Trazpiroben (TAK-906), a Novel, Potent Dopamine D2/D3 Receptor Antagonist for the Management of Gastroparesis	6
A Monoclonal Anti–Calcitonin Gene-Related Peptide Antibody Decreases Stress-Induced Colonic Hypersensitivity	6
Editorial Board	6
Elucidating the Function of ABCA13 in SHH-Medulloblastoma	6
Editorial Board	6
Beta-catenin C-terminus inhibition reduces vascular remodeling by precluding the expression of sphingosine-1-phosphate receptor-1	6
Patient iPSC-based high throughput drug screening identifies drug candidates involved in reduced tauopathy associated with Alzheimer’s disease	6
Editorial Board	6
Cardiac Effects of Novel Histamine H2 Receptor Agonists	6
A Novel Etomidate Analog EL-0052 Retains Potent Hypnotic Effect and Stable Hemodynamics without Suppressing Adrenocortical Function	6
Effects of 3,3’-Dichlorobiphenyl (PCB-11) on the expression of CYP2A, 2B, and 2F enzymes in the liver and brain of CYP2A6-humanized, CYP2B6-humanized, or wild-type mice	5
Sigma Ligand-mediated Cytosolic Calcium Modulation in BV2 Microglia Cells	5
Behavioral effects of fentanyl in presence or absence of chronic neuropathic pain in male and female rats	5
Propofol and salvianolic acid A synergistically attenuated hypoxia/reoxygenation induced H92 cells injury under high-glucose and high-fat condition via modulating CD36	5
Identification and Characterization of Palmitoylation Sites in the Organic Anion Transporting Polypeptide 1B1 (OATP1B1)	5
Knockout of γ-Adducin Promotes NG-Nitro-L-Arginine-Methyl-Ester–Induced Hypertensive Renal Injury	5
The Effects of the Dopamine Transporter Ligands JJC8-088 and JJC8-091 on Cocaine versus Food Choice in Rhesus Monkeys	5
The Functional Diversity of G Proteins in Opioid Receptor Signaling	5
Neurosteroid Mitigation of Developmental Neurological Dysfunction, Long- Term Epileptic Biomarkers, Chronic Neuroinflammation and Neurodegeneration in a Pediatric Rat Model of Organophosphate Exposure	5
Tricyclic Antidepressants Induce Anti-Inflammatory Signatures in Dorsal Root Ganglia after Prolonged Nerve Injury	5
Brain distribution and muscarinic receptor occupancy of an active metabolite of fesoterodine in rats	5
Pharmacological Evaluation of Vasant Kusumakar Rasa in High Fat Diet and Streptozotocin-Induced Diabetic Retinopathy in Rats	5
HNF4A-AS1 Alleviates Ritonavir-induced Liver Injury via HNRNPC-mediated HNF4A Degradation	5
Antiinflammatory and antioxidative role of pasteurized sauce produced from Capsicum spp and Lycopersicum esculentum against CCl4-induced hepatotoxicity in rats	5
Role of cyclophilin A overexpression in angiotensin II/mechanical stretch-induced vascular remodeling: Protective effect of adiponectin	5
Comparison of Mustard and Urticant Vesicating Agents’ Induced Cutaneous Lesions in Wild Type and Mast Cell Deficient Mice	5
Multiomics approach to interrogate translational regulation to GPCR signaling and its spatial bias	5
PXR activation attenuates liver fibrosis by down-regulating LECT2 and disrupting β-catenin/TCF4 interaction	5
Effects of Cannabinoids and a Cannabinoid Extract on Thermal Nociception and Conditioned Behavior	5
The serotonergic psychedelic N,N-Dipropyltryptamine prevents seizures in a mouse model of fragile X syndrome via an apparent non-serotonergic mechanism	5
Quantitative Prediction of OATP-Mediated Disposition and Biliary Clearance Using Human Liver Chimeric Mice	5
Ligustrazine Attenuates Liver Fibrosis by Targeting miR-145 Mediated Transforming Growth Factor-β/Smad Signaling in an Animal Model of Biliary Atresia	5
Novel Milli-fluidic Human Liver Tissue Chip and Multi-tissue Chip Platform with Continuous Recirculation for Predictive Pharmacokinetic Applications	5
Cannabinoid Tolerance in S426A/S430A x β-Arrestin 2 Knockout Double-Mutant Mice	5
Fatty Acid Metabolizing Cytochrome P450 4F11 as a Novel Drug Target for Lung Cancer Treatment	5
Efficacy of HS-10382 (TERN-701) in tumor xenograft models, a new investigational allosteric ABL1 kinase inhibitor as a potential treatment for CML	5
Identifying a Lead Candidate Anti-methamphetamine Monoclonal Antibody for IND-enabling Studies: Cross-reactivity and Locomotor Activity	5
Metabotropic glutamate receptor 3 activation modulates thalamic inputs to the nucleus accumbens and rescues schizophrenia-like physiological and behavioral deficits	5
The Nrf2 activator tBHQ promotes OVA-Elicited Food Allergy in Mice	5
Selective Phosphodiesterase 1 Inhibition Ameliorates Vascular Function, Reduces Inflammatory Response, and Lowers Blood Pressure in Aging Animals	5
Development of GPR183 antagonists for the treatment of neuropathic pain	5
Hypothalamic nociceptin neurons modulate stress-induced binge eating behaviors	5
Optogenetically modulating ventral tegmental area dopamine neuron activity alters dopamine transporter sensitivity to cocaine	5
HM15912, a Novel Long-Acting Glucagon-Like Peptide-2 Analog, Improves Intestinal Growth and Absorption Capacity in a Male Rat Model of Short Bowel Syndrome	5
Pharmacokinetic/Pharmacodynamic Modeling of Dexamethasone Anti-Inflammatory and Immunomodulatory Effects in LPS-Challenged Rats: A Model for Cytokine Release Syndrome	5
Non-Coding RNAs in Clinical Practice: From Biomarkers to Therapeutic Tools	5
A Putative New Melatonin Binding Site in Sheep Brain, MTx: Preliminary Observations and Characteristics	5
Efficacy modulation by targeting the sodium binding allosteric site in the delta opioid receptor	5
Understanding CXCR2 antagonism with a dynamic allosteric ternary complex model	5
Investigating the targeted anti-TNBC ability of small natural compound	5
Bioisosteric Replacement of Amides Linkers with 1, 2, 3-Triazoles for Improved Pharmacokinetics Without Losing Dopamine D4 Receptor Potency or Selectivity	5
Profiling and MALDI Imaging of Benzalkonium Chlorides and their Metabolites in the Mouse Kidney	5
Identification of Putative Novel Biomarkers of Organic Anion Transporter 1 and 3 for the Prediction of Transporter-Mediated Drug-Drug Interactions	5