Journal of Pharmacy and Pharmacology

Papers
(The median citation count of Journal of Pharmacy and Pharmacology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Tilianin obtained from Agastache mexicana inhibits monoamine oxidase and modifies depressive behavior in rats65
Scutellarein: a review of chemistry and pharmacology46
A review on the ethnopharmacology, phytochemistry and pharmacology of Polygonum hydropiper Linn.40
Hydroxyapatite-based nano-drug delivery system for nicotinamide mononucleotide (NMN): significantly enhancing NMN bioavailability and replenishing in vivo nicotinamide adenine dinucleotide (NAD40
Docetaxel in combination with metformin enhances antitumour efficacy in metastatic breast carcinoma models: a promising cancer targeting based on PEGylated liposomes38
Photoactivation of pheophorbide-a utilizing 670 nm LEDs elicits cancer suppressive effects in androgen-independent prostate cancer cellular models36
A comprehensive review of traditional uses, phytochemistry and pharmacology of Reynoutria genus36
Different protective capability of chlorogenic acid and quercetin against indomethacin-induced gastrointestinal ulceration31
Inhibition of human ether-à-go-go-related gene K+ currents expressed in HEK293 cells by three gingerol components from ginger31
In vitro antidiabetic activity of Treculia africana leaf extracts: identification of chlorogenic acid and α-mangostin28
Synergistic anti-tumour activity of ginsenoside Rg3 and doxorubicin on proliferation, metastasis and angiogenesis in osteosarcoma by modulating mTOR/HIF-1α/VEGF and EMT signalling pathways28
Study of the cardioprotective effects of crocin on Human Cardiac Myocyte cells and reduction of oxidative stress produced by aluminum phosphide poisoning27
Protopanaxadiol prevents cisplatin-induced acute kidney injury by regulating ferroptosis26
Pharmacokinetics-based chronoefficacy of Fuzi against chronic kidney disease25
Research progress regarding potential effects of traditional Chinese medicine on postoperative intestinal obstruction24
Novel therapeutic approaches for Parkinson’s disease by targeting brain cholesterol homeostasis24
Isatis indigotica: a review of phytochemistry, pharmacological activities and clinical applications24
Protective effects of duloxetine against chronic immobilisation stress-induced anxiety, depression, cognitive impairment and neurodegeneration in mice23
Phosphatidylinositol 3-kinase gamma participates in nimesulide-induced hepatic damage22
Nrf2 signalling pathway and autophagy impact on the preventive effect of green tea extract against alcohol-induced liver injury22
Pinus roxburghii alleviates bone porosity and loss in postmenopausal osteoporosis by regulating estrogen, calcium homeostasis and receptor activator of nuclear factor-κB, osteoprotegerin, cathe22
Vesicular drug delivery for the treatment of topical disorders: current and future perspectives20
Ganoderma lucidum ameliorates the diabetic nephropathy via down-regulatory effect on TGFβ-1 and TLR-4/NFκB signalling pathways20
β-Caryophyllene attenuates lipopolysaccharide-induced acute lung injury via inhibition of the MAPK signalling pathway20
Comparative bioavailability of curcuminoids from a water-dispersible high curcuminoid turmeric extract against a generic turmeric extract: a randomized, cross-over, comparative, pharmacokinetic study20
A honokiol-enriched Magnolia officinalis Rehder & E.H. Wilson. bark extract possesses anxiolytic-like activity with neuroprotective effect through the modulation of CB1 receptor20
β-Cyclodextrin-containing chitosan-oligonucleotide nanoparticles improve insulin bioactivity, gut cellular permeation and glucose consumption20
The hepatoprotective effect of silibinin after hepatic ischemia/reperfusion in a rat model is confirmed by immunohistochemistry and qRT-PCR20
The inhibitory effect of trimetazidine on detrusor contractility – a potential repositioning of trimetazidine for the treatment of overactive bladder20
Narrow Therapeutic Index drugs: clinical pharmacology perspective20
Corrigendum to: Distinct metabonomic signatures of Polygoni Multiflori Radix Praeparata against glucolipid metabolic disorders19
Design and optimization of 3D-bioprinted scaffold framework based on a new natural polymeric bioink19
Genus Barleria L. (Acanthaceae): a review of its taxonomy, cytogenetics, phytochemistry and pharmacological potential19
Hepatoprotective effect of Spirulina platensis against carbon tetrachloride-induced liver injury in male rats19
The application of natural compounds in uveal melanoma drug discovery19
Research progress on the pharmacy of tetramethylpyrazine and its pharmacological activity in cardiovascular and cerebrovascular diseases18
Enhancement of antiproliferative potential of metformin against melanoma mice B16 cells using an optimized liposomal drug delivery system18
In vitro and in vivo antihyperglycemic activity of the ethanol extract of Heritiera fomes bark and characterization of pharmacologically active phytomolecules18
Lianhuaqingwen alleviates p53-mediated apoptosis in alveolar epithelial cells to prevent LPS-induced ALI18
Mechanisms facilitating the uptake of carboxyl–polythene glycol-functionalized gold nanoparticles into multicellular spheroids18
Epidermal growth factor receptor as a potential target of momordin Ic to promote apoptosis of cholangiocarcinoma cells18
Attenuation of opioid tolerance by ETA receptor antagonist, BQ123, administered intravenously in mice17
Anti-inflammatory, anti-oxidant and anti-apoptotic effects of olive leaf extract in cardiac tissue of diabetic rats16
Azithromycin concentration in rabbits’ plasma and posterior segment of the eyes following oral drug administration: a dose-finding study for the application in ocular toxoplasmosis16
MTH-3 sensitizes oral cancer cells to cisplatin via regulating TFEB16
Development of a comprehensive method based on quantitative 1H NMR for quality evaluation of Traditional Chinese Medicine injection: a case study of Danshen Injection16
A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Shen-Kui-Tong-Mai granules on a rat model with chronic heart failure16
Jie Geng Tang reverses cisplatin resistance through the Nrf2 pathway in lung cancer16
Phytochemicals from medicinal plants from African forests with potentials in rheumatoid arthritis management16
Ginkgo biloba extracts (GBE) protect human RPE cells from t-BHP-induced oxidative stress and necrosis by activating the Nrf2-mediated antioxidant defence16
Gap junction is essential for the antidepressant effects of fluoxetine16
Combination of metabolomics and network pharmacology analysis to decipher the mechanisms of total flavonoids of Litchi seed against prostate cancer15
Investigation of the effect of concurrently administered carvedilol, atorvastatin and bile salts on intestinal absorption of linagliptin15
Solanine induces ferroptosis in colorectal cancer cells through ALOX12B/ADCY4 molecular axis15
Spotlight on Coenzyme Q10 in scopolamine-induced Alzheimer’s disease: oxidative stress/PI3K/AKT/GSK 3ß/CREB/BDNF/TrKB15
Patchouli alcohol against renal fibrosis of spontaneously hypertensive rats via Ras/Raf-1/ERK1/2 signalling pathway15
Effects of borneol combined with astragaloside IV and Panax notoginseng saponins regulation of microglia polarization to promote neurogenesis after cerebral ischaemia15
Study on the targeted regulation of Scutellaria baicalensis leaf on glutamine–glutamate metabolism and glutathione synthesis in the liver of d-gal ageing rats14
3-Demethyl-2-geranyl-4-prenylbellidifoline, a natural xanthone with diuretic and kidney protective properties14
Potential interactions between triazole antifungal agents and lorlatinib based on ultra-performance liquid chromatography-tandem mass spectrometry in rat plasma14
Indobufen alleviates ischemic stroke injury by regulating transcription factor NRF2 and inhibiting ATG5 expression14
Targeting the CCL2–CCR2 signaling pathway: potential implications of statins beyond cardiovascular diseases14
Icariside I reduces breast cancer proliferation, apoptosis, invasion, and metastasis probably through inhibiting IL-6/STAT3 signaling pathway14
Δ(9)-tetrahydrocannabinol protects cardiac tissue against endoplasmic reticulum and oxidative stresses, apoptosis, and inflammation in rats with hyperinsulinemia14
Phillyrin improves myocardial remodeling in salt-sensitive hypertensive mice by reducing endothelin1 signaling13
Inhalation of Curcumae Rhizoma volatile oil attenuates depression-like behaviours via activating the Nrf2 pathway to alleviate oxidative stress and improve mitochondrial dysfunction13
Assessment of efficacy of chrysin in diabetes-associated cardiac complications in chick embryo and murine model13
GL-V9 synergizes with oxaliplatin of colorectal cancer via Wee1 degradation mediated by HSP90 inhibition13
GC-MS- and LC-TOF-MS/MS-based ginger volatile oil serum analysis and the potential mechanism of the anticancer effect of serum component citral on MCF-7 breast cancer cells13
Chrysin bonded to β-d-glucose tetraacetate enhances its protective effects against the neurotoxicity induced by aluminum in Swiss mice13
Network pharmacology prediction, molecular docking, and molecular dynamics simulation-based strategy to explore the potential mechanism of Huashanshen dripping pill against asthma13
Dihydroisotanshinone I regulates ferroptosis via PI3K/AKT pathway to enhance cisplatin sensitivity in lung adenocarcinoma12
Schisandrin B ameliorates adjuvant-induced arthritis in rats via modulation of inflammatory mediators, oxidative stress, and HIF-1α/VEGF pathway12
The role of lncRNA ANRIL in the progression of hepatocellular carcinoma12
Doxorubicin-induced cardiotoxicity: causative factors and possible interventions12
Atractylodin inhibited the migration and induced autophagy in cholangiocarcinoma cells via PI3K/AKT/mTOR and p38MAPK signalling pathways12
Improvement of primary Sjögren’s syndrome salivary gland function by Xinfeng capsule and its effect on EGR1-STAT3 signaling pathway12
Effects of artemether on pancreatic islet morphology, islet cell turnover and α-cell transdifferentiation in insulin-deficient Glu CreERT2;ROSA26-eYFP diabetic m12
The potential of Ginkgo biloba in the treatment of human diseases and the relationship to Nrf2–mediated antioxidant protection12
3D Printing: an appealing technology for the manufacturing of solid oral dosage forms12
Dietary supplements and medicinal plants in urolithiasis: diet, prevention, and cure12
Ginsenoside Rg3 inhibits renal cell carcinoma cell migration, invasion, colony formation, and tube formation and enhances apoptosis through promoting the DNA demethylation and histone acetylation12
Disulfiram attenuates lipopolysaccharide-induced acute kidney injury by suppressing oxidative stress and NLRP3 inflammasome activation in mice12
Genipin improves obesity through promoting bile secretion and changing bile acids composition in diet-induced obese rats12
Near-infrared spectroscopy and HPLC combined with chemometrics for comprehensive evaluation of six organic acids in Ginkgo biloba leaf extract12
Melatonin alleviates high glucose-induced cardiomyocyte injury through suppressing mitochondrial FUNDC1-DRP1 axis12
3D-printed long-acting 5-fluorouracil implant to prevent conjunctival fibrosis in glaucoma12
Peimisine ameliorates DSS-induced colitis by suppressing Jak–Stat activation and alleviating gut microbiota dysbiosis in mice12
Medicinal plants from the Himalayan region for potential novel antimicrobial and anti-inflammatory skin treatments12
Ginsenoside Rb1 ameliorates hippocampal neuroinflammation in rats after intracerebral hemorrhage by inactivating the TLR4/NF-kB pathway11
Hypericin-mediated photodynamic therapy for the treatment of cancer: a review11
Physcion-8-O-β-d-glucoside interferes with the nuclear factor-κB pathway and downregulates P-glycoprotein expression to reduce paclitaxel resistance in ovarian cancer cells11
Natural product Pulsatilla saponin D sensitizes BRCA-proficient ovarian cancers to PARP inhibitors through inhibiting homologous recombination repair11
Anti-inflammatory effect of Adelia ricinella L. aerial parts11
Rosmarinic acid ameliorates septic-associated mortality and lung injury in mice via GRP78/IRE1α/JNK pathway11
Correction to: Current treatments for oropharyngeal squamous cell carcinoma and the move towards molecular therapy11
Fused deposition modelling 3D printing proof-of-concept study for personalised inner ear therapy11
A simple and effective method for the preparation of high-purity shikimic acid from chromatography wash effluent of Ginkgo biloba leaf extract by macroporous resin considering the effect of var11
In-line monitoring and endpoint determination of percolation process of herbal medicine using ultraviolet spectroscopy combined with convolutional neural network10
Aprepitant: an antiemetic drug, contributes to the prevention of acute lung injury with its anti-inflammatory and antioxidant properties10
Antimalarial primaquine for spinal sensory and motor blockade in rats10
Pharmacological intervention in oxidative stress as a therapeutic target in neurological disorders10
Potential therapeutic efficacy of pachymic acid in chronic kidney disease induced in rats: role of Wnt/β-catenin/renin–angiotensin axis10
Doxorubicin alters the disposition of phenytoin by reducing its metabolic elimination and binding affinity to serum albumin in rats10
Remifentanil protects heart from myocardial ischaemia/reperfusion (I/R) injury via miR-206-3p/TLR4/NF-κB signalling axis10
Evaluation of the effects of nanoparticles on the therapeutic function of platelet: a review10
Lupeol induces autophagy and apoptosis with reduced cancer stem-like properties in retinoblastoma via phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin inhibition10
Glucosamine attenuates drug resistance in Mitoxantrone-resistance breast cancer cells10
Effect of total glucosides of paeony and Tripterygium wilfordii polyglycosides on erythrocyte methotrexate polyglutamates in rats, analysed using ultra-high-performance liquid chromatography-ta10
Cilostazol attenuated prenatal valproic acid-induced behavioural and biochemical deficits in a rat model of autism spectrum disorder10
Chalcone-rich extracts from Lonchocarpus cultratus roots present in vitro leishmanicidal and immunomodulatory activity10
Hyperoside, a natural flavonoid compound, attenuates Triptolide-induced testicular damage by activating the Keap1-Nrf2 and SIRT1-PGC1α signalling pathway10
Prediction of the potential mechanism of compound gingerol against liver cancer based on network pharmacology and experimental verification10
Dose individualization of intravenous busulfan in pediatric patients undergoing bone marrow transplantation: impact and in vitro evaluation of infusion lag-time10
Targeting of MNK/eIF4E overcomes chemoresistance in cervical cancer10
Insulinotropic and antidiabetic properties of Eucalyptus citriodora leaves and isolation of bioactive phytomolecules10
Oral biopharmaceutics tools: recent progress from partnership through the Pharmaceutical Education and Research with Regulatory Links collaboration10
Angiotensin II upregulates endothelin receptors through the adenosine monophosphate-activated protein kinase/sirtuin 1 pathway in vascular smooth muscle cells10
Rhamnetin: a review of its pharmacology and toxicity10
Oxymatrine screened from Sophora flavescens by cell membrane immobilized chromatography relieves histamine-independent itch10
Tubastatin A suppresses the proliferation of fibroblasts in epidural fibrosis through phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) signalling pathway10
Study of the inclusion complexes formed between 4-phenylbutyrate and α-, β- and γ-cyclodextrin in solution and evaluation on their taste-masking properties9
Juglans mandshurica Maximowicz as a traditional medicine: review of its phytochemistry and pharmacological activity in East Asia9
Ezetimibe alleviates acetic acid-induced ulcerative colitis in rats: targeting the Akt/NF-κB/STAT3/CXCL10 signaling axis9
Polysaccharides of Grifola frondosa ameliorate oxidative stress and hypercholesterolaemia in hamsters fed a high-fat, high-cholesterol diet9
A comprehensive review of phytochemistry, pharmacology and quality control of plants from the genus Viola9
Phoenixin 14 ameloriates pancreatic injury in streptozotocin-induced diabetic rats by alleviating oxidative burden9
Limonin delays the progression of intervertebral disc degeneration in vivo and in vitro: the key role of the MAPK/NF-κB and necroptosis pathways9
Paeonol protects against acute pancreatitis by Nrf2 and NF-κB pathways in mice9
Protective effects of Radix Isatidis polysaccharide ameliorates obesity via promotion AMPK pathway in high-fat-diet-induced obese rats and 3T3-L1 adipocyte cells9
Role of cyclooxygenase pathways in bowel fibrotic remodelling in a murine model of experimental colitis9
PI3K/AKT/Nrf2 signalling pathway is involved in the ameliorative effects of xanthohumol on amyloid β-induced oxidative damage and bone loss9
An integrated strategy to explore the wine-processed mechanism of Corni Fructus on chronic renal failure based on metabolomics, network analysis and bioinformatics approaches9
Berberine suppresses the migration and invasion of colon cancer cells by inhibition of lipogenesis through modulation of promyelocytic leukemia zinc finger-mediated sterol-regulatory element binding p9
Eleutheroside E functions as anti-cervical cancer drug by inhibiting the phosphatidylinositol 3-kinase pathway and reprogramming the metabolic responses9
Effect of carvedilol on pharmacokinetics of sofosbuvir and its metabolite GS-331007: role of P-glycoprotein8
Exploration of the potential mechanism of aqueous extract of Artemisia capillaris for the treatment of non-alcoholic fatty liver disease based on network pharmacology and experimental verificat8
Shaoyao Gancao Decoction protects against dextran sulfate sodium-induced ulcerative colitis by down-regulating ferroptosis8
Inhaled exogenous thymosin beta 4 suppresses bleomycin-induced pulmonary fibrosis in mice via TGF-β1 signalling pathway8
Deciphering the mechanism of Chaihu Shugan San in the treatment of nonalcoholic steatohepatitis using network pharmacology and molecular docking8
Deciphering farnesol’s anti-arthritic and immunomodulatory potential by targeting multiple pathways: a combination of network pharmacology guided exploration and experimental verification8
Legumain: a potential biomarker for atherosclerosis8
Serum autotaxin level: a promising diagnostic biomarker in differentiating Graves’ disease and thyroiditis8
Jujuboside A ameliorates cognitive deficiency in delirium through promoting hippocampal E4BP4 in mice8
A prediction method for the individual serum concentration and therapeutic effect for optimizing adalimumab therapy in inflammatory bowel disease8
Astaxanthin protects against pirarubicin-induced H9c2 cardiomyocytes by adjusting microRNA-494-3p-mediated MDM4/p53 signalling pathway8
Anti-liver cancer therapeutic targets and safety of usenamine A in experimental liver cancer8
Raspberry ketone improves non-alcoholic fatty liver disease induced in rats by modulating sphingosine kinase/sphingosine-1-phosphate and toll-like receptor 4 pathways8
Renoprotective effect of liraglutide on diabetic nephropathy by modulation of Krüppel-like transcription factor 5 expression in rats8
The beneficial impact of curcumin on cardiac lipotoxicity8
Phenylethanoid glycosides extract from Cistanche deserticola ameliorates atherosclerosis in apolipoprotein E-deficient mice and regulates intestinal PPARγ-LXRα-ABCA1 pathway8
In silico evidence of bitopertin’s broad interactions within the SLC6 transporter family8
The therapeutic potential of curculigoside in poststroke depression: a focus on hippocampal neurogenesis and mitochondrial function8
Correction to: Evaluating the protective effect of dapsone on experimental osteoarthritis models induced by MIA in male rats8
A synthetic resveratrol–curcumin hybrid derivative exhibits chemopreventive effects on colon pre-neoplastic lesions by targeting Wnt/β-catenin signaling, anti-inflammatory and antioxidant pathways8
Exploring the clinical relevance of “Angico Gum”: an effective biopolymer for topical protection of oesophageal mucosa in gastroesophageal reflux disease patients7
Drug resistance via radixin-mediated increase of P-glycoprotein membrane expression during SNAI1-induced epithelial-mesenchymal transition in HepG2 cells7
Natural products derived from herbs as promising source for diarrhea predominant-irritable bowel syndrome via gut microbiota–serotonin pathway7
Novel peptide calcitonin gene-related peptide antagonists for migraine therapy7
Comparison of capecitabine concentrations determined by microsampling versus plasma concentrations for therapeutic drug monitoring: a pilot study7
Pharmacological investigation of genistein for its therapeutic potential against nitroglycerin-induced migraine headache7
Treatment of liver cancer cells with ethyl acetate extract of Crithmum maritimum permits reducing sorafenib dose and toxicity maintaining its efficacy7
Correction to: Curcumin solid dispersion-loaded in situ hydrogels for local treatment of injured vaginal bacterial infection and improvement of vaginal wound healing7
Erythrocyte membrane-camouflaged mesoporous silica composite nanoparticles for loading and controlled release of the hepatoprotective agent silibinin: A-synthesis and physicochemical characterization7
Fat mass and obesity-associated protein inhibit the pathology of rheumatoid arthritis through the NSUN2/SFRP1/Wnt/β-catenin signal axis7
Mitracarpus frigidus reduces lipid metabolism and PGE2 levels in inflammatory cells7
Schisandrin B restores M1/M2 balance through miR-124 in lipopolysaccharide-induced BV2 cells7
Hydroalcoholic extract of Araucaria sp. brown propolis alleviates ulcerative colitis induced by TNBS in rats by reducing inflammatory cell infiltration and oxidative damage7
Pharmacological properties and derivatives of saikosaponins—a review of recent studies7
Wedelolactone suppresses breast cancer growth and metastasis via regulating TGF-β1/Smad signaling pathway7
The natural polyphenol fisetin in atherosclerosis prevention: a mechanistic review7
Correction to: Patchouli alcohol against renal fibrosis of spontaneously hypertensive rats via Ras/Raf-1/ERK1/2 signalling pathway7
New insight into the molecular mechanism of TCM Bufei Huoxue formula for chronic obstructive pulmonary disease based on network pharmacology and experimental verification7
Ling-Gui-Zhu-Gan decoction protects against doxorubicin-induced myocardial injury by downregulating ferroptosis7
A review on phytochemical and therapeutic potential of Iris germanica6
Roles of pigment epithelium-derived factor in cardiomyocytes: implications for use as a cardioprotective therapeutic6
Protective effect of Allium scorodoprasum L. ethanolic extract in cyclophosphamide-induced hepatotoxicity model in rats6
Environmental toxicants, oxidative stress and health adversities: interventions of phytochemicals6
Alamandine protects against renal ischaemia–reperfusion injury in rats via inhibiting oxidative stress6
Preparation, characteristic, biological activities, and application of polysaccharide from Lilii Bulbus: a review6
Repurposing of sildenafil as antitumour; induction of cyclic guanosine monophosphate/protein kinase G pathway, caspase-dependent apoptosis and pivotal reduction of Nuclear factor kappa light chain enh6
Rhein induces apoptosis of AGS and MGC803 cells by regulating the Ras/PI3K/AKT and p38/MAPK signaling pathway6
The traditional uses, phytochemistry, pharmacology and toxicology of Dictamnus dasycarpus: a review6
Analysis of the clinical characteristics of the liver injury induced by levetiracetam6
Modulation of NF-κB and MAPK signalling pathways by hydrolysable tannin fraction from Terminalia chebula fruits contributes to its anti-inflammatory action in RAW 264.7 cells6
Production of mRNA lipid nanoparticles using advanced crossflow micromixing6
Fructus arctii: an overview on its traditional uses, pharmacology and phytochemistry6
PAMAM dendrimers as mediators of dermal and transdermal drug delivery: a review6
Thyme extract could overcome diabetes-induced reproductive dysfunction by inhibiting oxidative damage and increasing the expression of insulin receptor substrate and pyruvate kinase in the rat sperm6
Phloretin: a comprehensive review of its potential against diabetes and associated complications6
Ephedra sinica polysaccharide alleviates airway inflammations of mouse asthma-like induced by PM2.5 and ovalbumin via the regulation of gut microbiota and short chain fatty acid6
Engineering carrier nanoparticles with biomimetic moieties for improved intracellular targeted delivery of mRNA therapeutics and vaccines6
Mechanisms exploration of Xiaojin Pills on lung cancer based on metabolomics and network pharmacology6
The role of microRNAs on doxorubicin drug resistance in breast cancer6
Pharmacokinetics of nano- and microcrystal formulations of low solubility compounds after intramuscular injection to mice6
Integrated metabolomics and network pharmacology analysis to reveal the mechanisms of naringin against atherosclerosis6
N-palmitoylethanolamide synergizes the antinociception of morphine and gabapentin in the formalin test in mice6
Oligo/polysaccharides from Cyathula officinalis and Achyranthes bidentata: a review of structures and bioactivities6
The potential protective effect of the Polygonum hydropiper L against the development of fructose-induced oxidative stress and metabolic disorders in male Sprague-Dawely rats6
Homoharringtonine sensitizes pancreatic cancer to erlotinib by direct targeting and miRNA-130b-3p-mediated EphB4-JAK2-STAT3 axis6
Preparation and evaluation of reduction-responsive micelles based on disulfide-linked chondroitin sulfate A-tocopherol succinate for controlled antitumour drug release6
Effect of carrier material on the thermodynamic properties and recrystallization kinetics of andrographolide-solid dispersion6
The pleiotropic effects of statins in rheumatoid arthritis6
Decoding the power of saponins in ferroptosis regulation and disease intervention: a review6
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion6
Augmented cytotoxicity using the physical adsorption of Poloxamer 188 on allicin-loaded gelatin nanoparticles6
Co-administration of Ceratonia siliqua extract nanoparticles promotes the oral bioavailability and neurotherapeutic efficacy of donepezil in a dementia model6
N(Omega)-nitro-l-arginine methyl ester potentiates lidocaine analgesic and anaesthetic effect in rats6
p-Coumaric acid mitigates lipopolysaccharide induced brain damage via alleviating oxidative stress, inflammation and apoptosis6
Dopamine signalling in pancreatic islet cells and role in adaptations to metabolic stress6
Propolis prevents vascular endothelial dysfunction by attenuating inflammation and oxidative damage in the chronic unpredictable stress model of depression in rats6
Improvement of the bioavailability of curcumin by a supersaturatable self nanoemulsifying drug delivery system with incorporation of a hydrophilic polymer: in vitro and in vivo character6
Mechanism of dasabuvir inhibition of acetaminophen glucuronidation5
VX-765 ameliorates inflammation and extracellular matrix accumulation by inhibiting the NOX1/ROS/NF-κB pathway in diabetic nephropathy5
Croton grewioides essential oil and anethole reduce oxidative stress and improve growth of bovine primordial follicles during culture of ovarian tissue5
Indolocarbazole alkaloid Loonamycin A inhibits triple-negative breast cancer cell stemness and Notch signalling5
Inula japonica ameliorated the inflammation and oxidative stress in LPS-induced acute lung injury through the MAPK/NF-κB and Keap1/Nrf2 signalling pathways5
Traditional uses, hepatoprotective potential, and phytopharmacology of Tinospora cordifolia: a narrative review5
Metabolomic analysis identifies the regulation of lipid metabolism pathway as potential mechanisms of Jiangzhi decoction against non-alcoholic fatty liver disease5
An evaluation of the quality of Annona muricata leaf products5
Regorafenib inhibits growth, survival and angiogenesis in nasopharyngeal carcinoma and is synergistic with Mcl-1 inhibitor5
Circular RNA hsa_circ_0026344 suppresses gastric cancer cell proliferation, migration and invasion via the miR-590-5p/PDCD4 axis5
Forskolin alleviates cisplatin-induced acute renal toxicity in rats5
Shengqing Jiangzhuo capsule ameliorates diabetic nephropathy by improving Keap1/Nrf2 signaling pathway5
Development of a pharmacokinetic/pharmacodynamic evaluation model for osteomyelitis and usefulness of tedizolid as an alternative to vancomycin against MRSA osteomyelitis5
Function and inhibition of Haspin kinase: targeting multiple cancer therapies by antimitosis5
Phytochemical study and immunomodulatory activity of Fraxinus excelsior L.5
Investigation of polysaccharide from Radix Aconiti Lateralis Preparata (Fuzi) cardio protective effect on doxorubicin-induced chronic cardiotoxicity5
Novel resveratrol smart lipids; design, formulation, and biological evaluation of anticancer activity5
Cinobufagin: a promising therapeutic agent for cancer5
Albiflorin alleviation efficacy in osteoarthritis injury using in-vivo and in-vitro models5
Monotropein alleviates sepsis-elicited acute lung injury via the NF-κB pathway5
Cell-penetrating peptide-mediated delivery of therapeutic peptides/proteins to manage the diseases involving oxidative stress, inflammatory response and apoptosis5
Natural borneol enhances the anti-cerebral ischaemia efficacy of formononetin in MCAO/R rats by promoting its delivery in the brain5
Corrigendum to: Magnesium isoglycyrrhizinate prevents cadmium-induced activation of JNK and apoptotic hepatocyte death by reversing ROS-inactivated PP2A5
Alleviating vascular calcification with Bushen Huoxue formula in rats with chronic kidney disease by inhibiting the PTEN/PI3K/AKT signaling pathway through exosomal microRNA-325
Role of heme oxygenase-1 in the antidepressant-like effect of ursolic acid in the tail suspension test5
Population pharmacokinetic/pharmacodynamic evaluations of amikacin dosing in critically ill patients undergoing continuous venovenous hemodiafiltration5
Using ultra-performance liquid chromatography with linear ion trap-electrostatic field orbitrap mass spectrometry, network pharmacology, and molecular docking to explore the constituent targets and ac5
The genus Ranunculus L. (Ranunculus) in Asia: a review of its botany, traditional uses, phytochemistry, pharmacology, toxicity, and pharmaceutical preparations5
Fulvestrant alleviates cisplatin-induced acute kidney injury via repression of BNIP3-mediated apoptosis and autophagy5
Evaluation of in vivo and ex vivo pre-treated bone marrow-derived mesenchymal stem cells with resveratrol in streptozotocin-induced type 1 diabetic rats5
Toxicological and chemoprevention studies of Dalbergia ecastaphyllum (L.) Taub. stem, the botanical source of Brazilian red propolis5
The effect of patient’s body weight, infusion connection point, and infusion pump position on intravenous multi-infusion drug delivery at low infusion rates suitable for premature neonates5
The Clock gene regulates kainic acid-induced seizures through inhibiting ferroptosis in mice5
Protective effect of flavonoids from Passiflora edulis Sims on diabetic complications in rats4
Oxidative stress and inflammatory response of ghrelin on myocardial and aortic tissues in insulin-resistant rats4
α-Glucosidase and advanced glycation end products inhibition with Vernonia amygdalina root and leaf extracts: new data supporting the antidiabetic properties4
NUPR1 participates in YAP-mediate gastric cancer malignancy and drug resistance via AKT and p21 activation4
Down-regulation of long non-coding RNA antisense non-coding RNA in the INK4 locus suppresses OVCAR-3 cells proliferation and induction of apoptosis by Wnt/β-catenin4
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