Journal of Physiology-London

Article	Citations
Issue Information	171
Integrating respiration into sympathetic transduction to blood pressure	77
Issue Information	75
In Memoriam: Ann Silver	74
Issue Information	61
Issue Information	60
CrossTalk rebuttal	57
Motor learning changes the axon initial segment of the spinal motoneuron	57
Determinants and therapeutic potential of calcium handling abnormalities in atrial fibrillation: what can we learn from computer models?	56
High‐frequency electrical tuning and linear filter properties of Knollenorgan electroreceptors of mormyrid electric fish	56
Lack of compensatory mitophagy in skeletal muscles during sepsis	54
CKAMP44 controls synaptic function and strength of relay neurons during early development of the dorsal lateral geniculate nucleus	53
Diarrhoeal pathogenesis in Salmonella infection may result from an imbalance in intestinal epithelial differentiation through reduced Notch signalling	49
Severe hypoxaemic hypercapnia compounds cerebral oxidative–nitrosative stress during extreme apnoea: Implications for cerebral bioenergetic function	48
Decoding platelet loss in the hypoxic brain: What could go wrong?	48
Stroke severity shapes extracellular vesicle profiles and their impact on the cerebral endothelial cells	46
Peripheral chemoreflex restrains skeletal muscle blood flow during exercise in participants with treated hypertension	44
Augmenting workload drives T‐tubule assembly in developing cardiomyocytes	44
Goal‐directed action preparation in humans entails a mixture of corticospinal neural computations	44
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Changes in intra‐ and interlimb reflexes from forelimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats	42
Bayliss–Starling Prize Lecture: KATP channel pathophysiology – a whole‐body odyssey	41
Magnesium sulphate reduces tertiary gliosis but does not improve EEG recovery or white or grey matter cell survival after asphyxia in preterm fetal sheep	39
Opening the door to physiological impacts underlying opioid‐induced respiratory depression and therapeutic strategies: focus on fentanyl	39
Diversity of cells and signals in the cardiovascular system	39

The 70‐year search for the voltage‐sensing mechanism of ion channels	39
Engineering the immune and fibrotic response in VML	39
The ups and downs of intermittent hypoxia as a therapy for ventilatory insufficiency	38
Activation of the myosin motors in fast‐twitch muscle of the mouse is controlled by mechano‐sensing in the myosin filaments	37
Sensorimotor integration within the primary motor cortex by selective nerve fascicle stimulation	37
Unveiling sex differences in skeletal muscle metabolism: the role of HIF1α in normoxia	36
Action potentials in postganglionic sympathetic nerves depend on NaV1.7	36
Reply to ‘Reevaluating central versus peripheral contributions to maximal oxygen uptake: the role of muscle diffusive capacity’	35
Why you should pay more attention to your cells’ sex	35
The astrocytic Na+‐HCO3− cotransporter, NBCe1, is dispensable for respiratory chemosensitivity	35
The endocrine kidney: tampering with oxygen sensors may change your character	35
Cerebral uptake of microvesicles occurs in normocapnic but not hypocapnic passive hyperthermia in young healthy male adults	35
Nitric oxide synthase inhibition in healthy adults reduces regional and total cerebral macrovascular blood flow and microvascular perfusion	35
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Mitochondrial haplotype and sex modulate responses to endurance exercise training	33
Corticothalamic modulation of somatosensory thalamic tactile processing	33
Ventricular arrhythmogenic remodelling in diet‐induced metabolic syndrome driven by right‐to‐left regional differences in action potential duration and dominant frequency gradients	33
Hypertension increases sympathetic neuron activity by enhancing intraganglionic cholinergic collateral connections	33
Ocular surface information seen from the somatosensory thalamus and cortex	33
The impact of androgens on cardiovascular control mechanisms in polycystic ovary syndrome: Recent advances and translational approaches	32
Chronic intermittent hypoxia‐induced cardiovascular and renal dysfunction: from adaptation to maladaptation	32
Mitochondrial carbonic anhydrase VA and VB: properties and roles in health and disease	31
‘Evolutionary poker’: an agent‐based model of interactome emergence and epistasis tested against Lenski's long‐term E. coli experiments	31
Issue Information	31
Pregnancy does not affect progression of mild experimental asthma in sheep	31
Issue Information	31
Heartbeat‐related activity in the anterior thalamus differs between phasic and tonic REM sleep	31
An experiment of nature links muscle glycogen unavailability with very high fat oxidation rates despite low aerobic fitness	30
Issue Information	29
Volitional exercise elicits physiological and molecular improvements in the severe D2.mdx mouse model of Duchenne muscular dystrophy	29
Issue Information	29
Response to ‘Comment on Wyrwoll et al., 2022: Long‐term exposure of mice to 890 ppm atmospheric CO2 alters growth trajectories and hyperactive behaviours in adults’ by Norman R. Saunders an	29
Want to hear ClC‐6 sing? Push your amp to eleven	29
Macrophage microvesicle‐derived circ_YTHDF2 in methamphetamine‐induced chronic lung injury	28
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Hypoxic sensitivity and burden predict propensity for respiratory plasticity in humans	28
Corrigendum	28
Action potential amplitude and baroreflex resetting of action potential clusters mediate hypoxia‐induced sympathetic long‐term facilitation	28
Muscle memory theory: Implications for health, athletic performance and sports integrity	28
Presynaptic H3 receptor: A modulator for CeL excitatory‐inhibitory homeostasis	28
Muscle déjà vu: are myonuclei the blueprint for muscle regrowth?	28
Unravelling the mysteries of mitochondria in health and disease	27
Muscarinic regulation of the neuronal Na+/K+‐ATPase in rat hippocampus	27
A cross‐species validation of single‐beat metrics of cardiac contractility	27
Sexual dimorphism: increased sterol excretion leads to hypocholesterolaemia in female hyperbilirubinaemic Gunn rats	27
The neural control of movement: a century of in vivo motor unit recordings is the legacy of Adrian and Bronk	27
Functional development and regeneration of hair cells in the zebrafish lateral line	27
Optical mapping of contracting hearts	27
Glucocorticoids regulate mitochondrial fatty acid oxidation in fetal cardiomyocytes	26
Release your inhibitions: The role of post‐inhibitory rebound and synaptic inhibition in the generation of expiratory activity	26

Loss of the alpha subunit distal furin cleavage site blunts ENaC activation following Na+ restriction	25
Making ‘sense’ of what happens on the inside: il‘LUMEN'ating the effects of intestinal distention on calcium activity in enteric neurons	25
The fallacy of functional nomenclature in the kingdom of biological multifunctionality: physiological and evolutionary considerations on ion channels	25
Too hot to handle? Unveiling gut permeability during exertional heat stress	25
Efficiency of cycling exercise: Understanding the physiology	25
Multispectral brain connectivity during visual attention distinguishes controlled from uncontrolled hypertension	24
Thermodynamic limitations on brain oxygen metabolism: physiological implications*	24
Towards unravelling the exercise‐induced adaptations in circulating extracellular vesicles	24
Multi‐scale modelling of the effects of ageing, hypertension and exercise on the cerebral vasculature	24
Muscle matters: exploring the contributions of ageing skeletal muscle to metabolic syndrome	24
The non‐invasive assessment of muscle fibre size: has the future arrived?	24
Reply from D. R. Perkins and Mike Stembridge	24
Microglial phagocytosis in epilepsy: Mechanisms and impact	23
Insulin potentiates the response to capsaicin in dorsal root ganglion neurons in vitro and muscle afferents ex vivo in normal healthy rodents	23
The diverse functions of the DEG/ENaC family: linking genetic and physiological insights	23
Dietary nitrate supplementation improves age‐associated neuromuscular outcomes: A step towards healthy ageing	23
Ageing reduces persistent inward current contribution to motor neurone firing: Potential mechanisms and the role of exercise	23
Synaptic loss in motor neurons precipitates age‐related dysphagia: Middle agers gotta keep in touch!	22
Cathodal bilateral transcranial direct‐current stimulation regulates selenium to confer neuroprotection after rat cerebral ischaemia–reperfusion injury	22
Fast and sensitive GCaMP calcium indicators for neuronal imaging	22
The key to our hearts: Unlocking fundamental sex differences in mouse cardiomyocyte calcium‐cycling	22
Extracellular vesicles and their non‐coding RNA cargos: Emerging players in cardiovascular disease	22
Inflammatory gene expression during acute high‐altitude exposure	22
Bioavailable testosterone and androgen receptor activation, but not total testosterone, are associated with muscle mass and strength in females	22
Speciation by physiological selection of environmentally acquired traits	22
Issue Information	22
Situating physiology within evolutionary theory	22
The potential therapeutic benefits of low frequency haemodynamic oscillations	22
Properties and modulation of excitatory inputs to the locus coeruleus	22
Hyperglycaemia, pregnancy outcomes and maternal metabolic disease risk during pregnancy and lactation in a lean gestational diabetes mouse model	22
Issue Information	22
Nav1.2 and BK channel interaction shapes the action potential in the axon initial segment	21
Ageing impairs endothelium‐dependent vasodilatation and alters redox signalling in diaphragm arterioles from male and female Fischer‐344 rats	21
Intrinsic motoneuron properties in typical human development	21
Central α2‐adrenergic mechanisms regulate human sympathetic neuronal discharge strategies	21
The cardiac sodium channel from function to dysfunction	21
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Crosstalk between biochemical signalling network architecture and trafficking governs AMPAR dynamics in synaptic plasticity	21
Translating physiology of the arterial chemoreflex into novel therapeutic interventions targeting carotid bodies in cardiometabolic disorders	21
Flex and flow: are we receptive to all females in muscle physiology research?	21
The pathological blood flow steal phenomenon limits exercise tolerance in pulmonary hypertensive rats	21
Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition	20
Exercise intolerance in pulmonary hypertension: robbing Peter to pay Paul	20
Neuroinflammation and the immune system in hypoxic ischaemic brain injury pathophysiology after cardiac arrest	20
A systematic review of computational models for the design of spinal cord stimulation therapies: from neural circuits to patient‐specific simulations	20
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Whole‐body metabolic rate is influenced by muscle fibre typology	20
Hydrogen peroxide and phosphoinositide metabolites synergistically regulate a cation current to influence neuroendocrine cell bursting	20
Circadian patterns of heart rate variability in fetal sheep after hypoxia‐ischaemia: A biomarker of evolving brain injury	20
Issue Information	20
The complexity of Nrf2 in experimental autoimmune myositis‐induced mice	20
An automated respiratory data pipeline for waveform characteristic analysis	20
Critical molecular outcomes of time‐restricted feeding during ageing: a look beyond body composition	20
Identification of a helix–turn–helix motif for high temperature dependence of vanilloid receptor TRPV2	19
Who's on first … Na+, HCO3− or CO32−?	19
Pump up the volume: breathing facilitates cardiac output during exercise by mechanical action	19
TET2 confers a mechanistic link of microRNA‐210 and mtROS in hypoxia‐suppressed spontaneous transient outward currents in uterine arteries of pregnant sheep	19
Mechano‐electrical interactions and heterogeneities in wild‐type and drug‐induced long QT syndrome rabbits	19
Function of K2P channels in the mammalian node of Ranvier	19
Past questions, present results, future perspectives: Interacting chemosensitive areas and the hypercapnic ventilatory response	19
Use it or lose it: protecting ageing muscles with lifelong recreational exercise	19
Characterizing the effects of type I collagen alterations on respiratory function in mouse models with varying severity of osteogenesis imperfecta	19
Revisiting the limitation to with ageing: is mitochondrial (dys)function the key?	19
Beeting atrophy: dietary nitrate to protect the powerhouse of the cell?	19
Oncomodulin regulates spontaneous calcium signalling and maturation of afferent innervation in cochlear outer hair cells	19
Adrenergic restraint of blood flow and high‐altitude acclimatization	19
Exosomes and the cardiovascular system: role in cardiovascular health and disease	18
Particle‐swarm based modelling reveals two distinct classes of CRHPVN neurons	18
A game of chest: Where does blood volume shift?	18
Maternal sleep behaviours preceding fetal heart rate events on cardiotocography	18
Glyoxalase 1 overexpression improves neurovascular coupling and limits development of mild cognitive impairment in a mouse model of type 1 diabetes	18
Encoding of vestibular and optic flow cues to self‐motion in the posterior superior temporal polysensory area	18
Something's fishy: cardiovascular ATP‐sensitive K+ channels in zebrafish	18
Muscular strength, endothelial function and cognitive disorders: state of the art	18
CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative and non‐associative learning	18
Reorganization of mitochondria–organelle interactions during postnatal development in skeletal muscle	18
The time is now: regular exercise maintains vascular health in ageing women	18
Ketogenic diet and ketone salts differentially improve cardiometabolic complications in an HFpEF rat model	18
The effects of local vibration inducing a tonic vibration reflex or movement illusion on acute modulations of corticospinal excitability	18
Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse	18

A detailed mathematical model of the human atrial cardiomyocyte: integration of electrophysiology and cardiomechanics	18
Towards spatially selective efferent neuromodulation: anatomical and functional organization of cardiac fibres in the porcine cervical vagus nerve	18
The post‐arteriole transitional zone: a specialized capillary region that regulates blood flow within the CNS microvasculature	17
Issue Information	17
Issue Information	17
Exercise, healthy ageing, and the potential role of small extracellular vesicles	17
Novel regenerative drug, SPG302 promotes functional recovery of diaphragm muscle activity after cervical spinal cord injury	17
Issue Information	17
Activation of TRPA1 and TRPM3 triggers Ca2+ waves in central terminals of sensory neurons and facilitates synaptic activity in the spinal dorsal horn	17
Mitochondrial function in brain and muscle metabolism: the crucial role during early sensorimotor development	17
Pathogenic TNNT1 variants are associated with aberrant thin filament compliance and myofibre hyper‐contractility	17
Enter Sandman: An eye opening opinion of cardiovascular disease prevention in cervical spinal cord injury	17
Evolution of rod bipolar cells and rod vision	17
Stem cell approaches for tendon repair: delusion or insight	17
Issue Information	17
Homeostasis and evolution in relation to regeneration and repair	16
The legacy of A. V. Hill's Nobel Prize winning work on muscle energetics	16
Becoming mindful of mindfulness: a promising approach to reducing sympathetic nervous system overactivity in chronic kidney disease	16
Fluorescent biosensor imaging meets deterministic mathematical modelling: quantitative investigation of signalling compartmentalization	16
Plasma measurements of the dual sugar test reveal carbohydrate immediately alleviates intestinal permeability caused by exertional heat stress	16
Recurrence of ventricular fibrillation in out‐of‐hospital cardiac arrest: Clinical evidence and underlying ionic mechanisms	16
Extracellular vesicles and their microRNA cargo in ischaemic stroke	16
Notch1 promotes ordered revascularization through Semaphorin 3g modulation of downstream vascular patterning signalling factors	16
Age‐related diaphragm dysfunction: could diaphragm arteriole dysfunction be to blame?	16
Untangling age and menopause: vascular mechanisms for cardiovascular disease risk in females	16
Annual Prize Lecture 2024: Endogenous physiological mechanisms as basis for the treatment of obesity and type 2 diabetes	16
Channelling protons out of the heart	16
Symptom‐modifying strategy to treat upper respiratory tract infections: a clinical and mechanistic evidence of ColdZyme	16
Cross Talk proposal: Human‐derived brain tissue is a better epilepsy model than animal‐based approaches	16
Endurance exercise training changes the limitation on muscle V̇O2max${\dot{V}}_{{{\mathrm{O}}}_{\mathrm{2}}{\mathrm{max}}}$ in normoxia from the capacity to utilize O2 to the capacity to tr	16
Expiratory flow limitation during exercise: why does it ‘suck’ so much?	16
Deficiency of PKA‐mediated SNAP‐25b phosphorylation destabilizes exocytotic fusion pores and reduces the interactions of t‐SNAREs	16
Physiological mechanisms of unexplained (functional) gastrointestinal disorders	16
Muscle‐derived IL‐1β regulates EcSOD expression via the NBR1‐p62‐Nrf2 pathway in muscle during cancer cachexia	16
The repair capacity spectrum of human skeletal muscle injury from sports to surgical trauma settings	16
Activating thermogenesis to combat obesity: hot topic or cold front?	16
A multimodal exercise countermeasure prevents the negative impact of head‐down tilt bed rest on muscle volume and mitochondrial health in older adults	16
Enhancing stroke risk stratification in atrial fibrillation through non‐Newtonian blood modelling and Gaussian process emulation	16
Loss of anoctamin 1 reveals a subtle role for BK channels in lymphatic muscle action potentials	15
Time course and fibre type‐dependent nature of calcium‐handling protein responses to sprint interval exercise in human skeletal muscle	15
Directional sensitivity of C‐low‐threshold mechanoreceptors: insights from in vivo calcium imaging	15
The complex function of macrophages and their subpopulations in metabolic injury associated fatty liver disease	15
Muscle–fat crosstalk: effects of exercise on brown adipose tissue; what do we know?	15
High altitude differentially modulates potassium channel‐evoked vasodilatation in pregnant human myometrial arteries	15
What is fetal growth restriction and how might we know?	15
When right ventricular pressure meets volume: The impact of arrival time of reflected waves on right ventricle load in pulmonary arterial hypertension	15
Ca2+ signalling in interstitial cells of Cajal contributes to generation and maintenance of tone in mouse and monkey lower oesophageal sphincters	15
Comparison of excitation–contraction coupling between Drosophila and vertebrate muscle	15
Beyond the madness: a balanced approach to standardization, practicality and innovation in exercise physiology threshold assessment	15
Ubiquitin ligase signalling networks shape presynaptic development, function and disease	15
Presynaptic quantal size enhancement counteracts post‐tetanic release depression	15
Exercise affects fatty acid oxidation and lipid droplets in patients with type 2 diabetes	15
A narrative review of periodic breathing during sleep at high altitude: From acclimatizing lowlanders to adapted highlanders	15
Phase‐dependent local brain states determine the impact of image‐guided transcranial magnetic stimulation on motor network electroencephalographic synchronization	15
Cardiac programming in the placentally restricted sheep fetus in early gestation	15
Scale‐invariant changes in corticospinal excitability reflect multiplexed oscillations in the motor output	15
Rebuttal from Amy Richardson and Gareth Morris	15
Insulin, Nobel laureates and The Journal of Physiology	15
Vaping for two: unravelling the mysteries of E‐cigarettes and fetal vascular health	15
Can muscle typology explain the inter‐individual variability in resistance training adaptations?	14
Profoundly lower muscle mass and rate of contractile protein synthesis in boys with Duchenne muscular dystrophy	14
Pancreatic acinar cell signalling and function exhibit an absolute requirement for activation of Gαq	14
Stepping up to inspire in muscular dystrophy	14
School of ‘hard NOX’ for the ageing artery	14
Issue Information	14
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Fasting and the short‐term consumption of a ketogenic diet are sufficient interventions to protect against OLZ‐induced hyperglycaemia in mice	14
Paraventricular nucleus projections to the nucleus tractus solitarii are essential for full expression of hypoxia‐induced peripheral chemoreflex responses	14
Autonomic modulation with mindfulness‐based stress reduction in chronic kidney disease: a randomized controlled trial	14
Pedalling toward a deeper understanding of exercise effects on immune function	14
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Issue Information	14
Oxytocin and corticotropin‐releasing hormone exaggerate nucleus tractus solitarii neuronal and synaptic activity following chronic intermittent hypoxia	14
Interstitial cells of Cajal – pacemakers of the gastrointestinal tract	14
Neural coordination of bilateral hand movements: evidence for an involvement of brainstem motor centres	14
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BK channels at dendritic spines: A mechanism for coupling morphology, plasticity and information storage?	14
The link between sarcopenic obesity and Alzheimer's disease: a brain‐derived neurotrophic factor point of view	14
A very brief note on why bacterial evolution has physiology	13
RyR2‐dependent modulation of neuronal hyperactivity: A potential therapeutic target for treating Alzheimer's disease	13
Biophysical modelling of intrinsic cardiac nervous system neuronal electrophysiology based on single‐cell transcriptomics	13
What can insects teach us about hearing loss?	13
Situating homeostasis in organisms: maintaining organization through time	13
Channelling calcium signals to therapeutics	13
Early heart and skeletal muscle mitochondrial response to a moderate hypobaric hypoxia environment	13
Adaptive spike threshold dynamics associated with sparse spiking of hilar mossy cells are captured by a simple model	13
Divergent splanchnic sympathetic efferent nerve pathways regulate interleukin‐10 and tumour necrosis factor‐α responses to endotoxaemia	13
Role of the sympathetic nervous system and acute intermittent hypoxia in haemodynamic changes in a spinal cord injury model	13
Remote ischaemic preconditioning – translating cardiovascular benefits to humans	13
Startling acoustic stimuli hasten reflexive choice reaching tasks by enhancing, but not changing the timing of, express visuomotor responses	13
The role of female sex hormones and oral combined contraceptives in metabolic adaptations	13
How neural networks walk and chew gum	13
In Memoriam: Gary Mawe	13
Bile acid‐ and ethanol‐mediated activation of Orai1 damages pancreatic ductal secretion in acute pancreatitis	13
Metformin in pregnancy: a re‐examination of its safety	13