Journal of Physiology-London

Article	Citations
Issue Information	163
Pregnancy does not affect progression of mild experimental asthma in sheep	75
Integrating respiration into sympathetic transduction to blood pressure	74
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Goal‐directed action preparation in humans entails a mixture of corticospinal neural computations	59
Issue Information	57
In Memoriam: Ann Silver	54
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Motor learning changes the axon initial segment of the spinal motoneuron	52
CrossTalk rebuttal	52
Decoding platelet loss in the hypoxic brain: What could go wrong?	51
Determinants and therapeutic potential of calcium handling abnormalities in atrial fibrillation: what can we learn from computer models?	51
Stroke severity shapes extracellular vesicle profiles and their impact on the cerebral endothelial cells	47
Augmenting workload drives T‐tubule assembly in developing cardiomyocytes	46
‘Evolutionary poker’: an agent‐based model of interactome emergence and epistasis tested against Lenski's long‐term E. coli experiments	45
Allosteric modulation of cardiac myosin mechanics and kinetics by the conjugated omega‐7,9 trans‐fat rumenic acid	44
Engineering the immune and fibrotic response in VML	43
Opening the door to physiological impacts underlying opioid‐induced respiratory depression and therapeutic strategies: focus on fentanyl	42
Lack of compensatory mitophagy in skeletal muscles during sepsis	41
Activation of the myosin motors in fast‐twitch muscle of the mouse is controlled by mechano‐sensing in the myosin filaments	41
The ups and downs of intermittent hypoxia as a therapy for ventilatory insufficiency	41
Sensorimotor integration within the primary motor cortex by selective nerve fascicle stimulation	40
Action potentials in postganglionic sympathetic nerves depend on NaV1.7	39
Diversity of cells and signals in the cardiovascular system	38

Reply to ‘Reevaluating central versus peripheral contributions to maximal oxygen uptake: the role of muscle diffusive capacity’	37
Peripheral chemoreflex restrains skeletal muscle blood flow during exercise in participants with treated hypertension	37
Unveiling sex differences in skeletal muscle metabolism: the role of HIF1α in normoxia	37
Cerebral uptake of microvesicles occurs in normocapnic but not hypocapnic passive hyperthermia in young healthy male adults	36
The astrocytic Na+‐HCO3− cotransporter, NBCe1, is dispensable for respiratory chemosensitivity	36
The endocrine kidney: tampering with oxygen sensors may change your character	35
Why you should pay more attention to your cells’ sex	35
Severe hypoxaemic hypercapnia compounds cerebral oxidative–nitrosative stress during extreme apnoea: Implications for cerebral bioenergetic function	35
A more holistic view could contribute to our understanding of ‘silent hypoxaemia’ in Covid‐19 patients	35
Nitric oxide synthase inhibition in healthy adults reduces regional and total cerebral macrovascular blood flow and microvascular perfusion	35
Diarrhoeal pathogenesis in Salmonella infection may result from an imbalance in intestinal epithelial differentiation through reduced Notch signalling	34
Magnesium sulphate reduces tertiary gliosis but does not improve EEG recovery or white or grey matter cell survival after asphyxia in preterm fetal sheep	34
Chronic intermittent hypoxia‐induced cardiovascular and renal dysfunction: from adaptation to maladaptation	33
CKAMP44 controls synaptic function and strength of relay neurons during early development of the dorsal lateral geniculate nucleus	33
Mitochondrial carbonic anhydrase VA and VB: properties and roles in health and disease	33
Changes in intra‐ and interlimb reflexes from forelimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats	33
Heartbeat‐related activity in the anterior thalamus differs between phasic and tonic REM sleep	32
The 70‐year search for the voltage‐sensing mechanism of ion channels	32
Ventricular arrhythmogenic remodelling in diet‐induced metabolic syndrome driven by right‐to‐left regional differences in action potential duration and dominant frequency gradients	31
The impact of androgens on cardiovascular control mechanisms in polycystic ovary syndrome: Recent advances and translational approaches	31
Corticothalamic modulation of somatosensory thalamic tactile processing	31
Ocular surface information seen from the somatosensory thalamus and cortex	31
Hypertension increases sympathetic neuron activity by enhancing intraganglionic cholinergic collateral connections	31
Bayliss–Starling Prize Lecture: KATP channel pathophysiology – a whole‐body odyssey	31
Issue Information	30
Mitochondrial haplotype and sex modulate responses to endurance exercise training	30
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An experiment of nature links muscle glycogen unavailability with very high fat oxidation rates despite low aerobic fitness	29
Issue Information	28
Want to hear ClC‐6 sing? Push your amp to eleven	28
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Hypoxic sensitivity and burden predict propensity for respiratory plasticity in humans	28
Response to ‘Comment on Wyrwoll et al., 2022: Long‐term exposure of mice to 890 ppm atmospheric CO2 alters growth trajectories and hyperactive behaviours in adults’ by Norman R. Saunders an	28
Volitional exercise elicits physiological and molecular improvements in the severe D2.mdx mouse model of Duchenne muscular dystrophy	28
Synaptic loss in motor neurons precipitates age‐related dysphagia: Middle agers gotta keep in touch!	27
Extracellular vesicles and their non‐coding RNA cargos: Emerging players in cardiovascular disease	27
Corrigendum	27
The neural control of movement: a century of in vivo motor unit recordings is the legacy of Adrian and Bronk	27
Muscarinic regulation of the neuronal Na+/K+‐ATPase in rat hippocampus	27
Muscle déjà vu: are myonuclei the blueprint for muscle regrowth?	27
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Presynaptic H3 receptor: A modulator for CeL excitatory‐inhibitory homeostasis	27
Functional development and regeneration of hair cells in the zebrafish lateral line	26
Ageing reduces persistent inward current contribution to motor neurone firing: Potential mechanisms and the role of exercise	26
Back‐seat driver: the fetus is not a passive passenger!	26
Sexual dimorphism: increased sterol excretion leads to hypocholesterolaemia in female hyperbilirubinaemic Gunn rats	26
Release your inhibitions: The role of post‐inhibitory rebound and synaptic inhibition in the generation of expiratory activity	25
Glucocorticoids regulate mitochondrial fatty acid oxidation in fetal cardiomyocytes	25
Efficiency of cycling exercise: Understanding the physiology	25

Speciation by physiological selection of environmentally acquired traits	25
Unravelling the mysteries of mitochondria in health and disease	25
Making ‘sense’ of what happens on the inside: il‘LUMEN'ating the effects of intestinal distention on calcium activity in enteric neurons	25
Action potential amplitude and baroreflex resetting of action potential clusters mediate hypoxia‐induced sympathetic long‐term facilitation	25
The fallacy of functional nomenclature in the kingdom of biological multifunctionality: physiological and evolutionary considerations on ion channels	24
Situating physiology within evolutionary theory	24
The non‐invasive assessment of muscle fibre size: has the future arrived?	23
Muscle matters: exploring the contributions of ageing skeletal muscle to metabolic syndrome	23
Towards unravelling the exercise‐induced adaptations in circulating extracellular vesicles	23
Multispectral brain connectivity during visual attention distinguishes controlled from uncontrolled hypertension	23
Macrophage microvesicle‐derived circ_YTHDF2 in methamphetamine‐induced chronic lung injury	23
Optical mapping of contracting hearts	23
Too hot to handle? Unveiling gut permeability during exertional heat stress	23
Loss of the alpha subunit distal furin cleavage site blunts ENaC activation following Na+ restriction	23
Thermodynamic limitations on brain oxygen metabolism: physiological implications*	23
Reply from D. R. Perkins and Mike Stembridge	23
A cross‐species validation of single‐beat metrics of cardiac contractility	23
Cathodal bilateral transcranial direct‐current stimulation regulates selenium to confer neuroprotection after rat cerebral ischaemia–reperfusion injury	22
Inflammatory gene expression during acute high‐altitude exposure	22
Multi‐scale modelling of the effects of ageing, hypertension and exercise on the cerebral vasculature	22
Hyperglycaemia, pregnancy outcomes and maternal metabolic disease risk during pregnancy and lactation in a lean gestational diabetes mouse model	22
Insulin potentiates the response to capsaicin in dorsal root ganglion neurons in vitro and muscle afferents ex vivo in normal healthy rodents	22
The potential therapeutic benefits of low frequency haemodynamic oscillations	22
The diverse functions of the DEG/ENaC family: linking genetic and physiological insights	22
Fast and sensitive GCaMP calcium indicators for neuronal imaging	22
Bioavailable testosterone and androgen receptor activation, but not total testosterone, are associated with muscle mass and strength in females	22
The key to our hearts: Unlocking fundamental sex differences in mouse cardiomyocyte calcium‐cycling	21
Muscle memory theory: Implications for health, athletic performance and sports integrity	21
Intrinsic motoneuron properties in typical human development	21
Properties and modulation of excitatory inputs to the locus coeruleus	21
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Central α2‐adrenergic mechanisms regulate human sympathetic neuronal discharge strategies	21
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Whole‐body metabolic rate is influenced by muscle fibre typology	21
Exercise intolerance in pulmonary hypertension: robbing Peter to pay Paul	21
The time is now: regular exercise maintains vascular health in ageing women	20
Pathogenic TNNT1 variants are associated with aberrant thin filament compliance and myofibre hyper‐contractility	20
The complexity of Nrf2 in experimental autoimmune myositis‐induced mice	20
Critical molecular outcomes of time‐restricted feeding during ageing: a look beyond body composition	20
Hydrogen peroxide and phosphoinositide metabolites synergistically regulate a cation current to influence neuroendocrine cell bursting	20
Flex and flow: are we receptive to all females in muscle physiology research?	20
Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition	20
An automated respiratory data pipeline for waveform characteristic analysis	20
Nav1.2 and BK channel interaction shapes the action potential in the axon initial segment	20
The pathological blood flow steal phenomenon limits exercise tolerance in pulmonary hypertensive rats	20
Use it or lose it: protecting ageing muscles with lifelong recreational exercise	19
TET2 confers a mechanistic link of microRNA‐210 and mtROS in hypoxia‐suppressed spontaneous transient outward currents in uterine arteries of pregnant sheep	19
Revisiting the limitation to with ageing: is mitochondrial (dys)function the key?	19
Crosstalk between biochemical signalling network architecture and trafficking governs AMPAR dynamics in synaptic plasticity	19
Glyoxalase 1 overexpression improves neurovascular coupling and limits development of mild cognitive impairment in a mouse model of type 1 diabetes	19
Circadian patterns of heart rate variability in fetal sheep after hypoxia‐ischaemia: A biomarker of evolving brain injury	19
A game of chest: Where does blood volume shift?	19
The cardiac sodium channel from function to dysfunction	19
Neuroinflammation and the immune system in hypoxic ischaemic brain injury pathophysiology after cardiac arrest	19
Adrenergic restraint of blood flow and high‐altitude acclimatization	19
Characterizing the effects of type I collagen alterations on respiratory function in mouse models with varying severity of osteogenesis imperfecta	19
Novel regenerative drug, SPG302 promotes functional recovery of diaphragm muscle activity after cervical spinal cord injury	19
Mechano‐electrical interactions and heterogeneities in wild‐type and drug‐induced long QT syndrome rabbits	18
Maternal sleep behaviours preceding fetal heart rate events on cardiotocography	18
Beeting atrophy: dietary nitrate to protect the powerhouse of the cell?	18
Particle‐swarm based modelling reveals two distinct classes of CRHPVN neurons	18
Encoding of vestibular and optic flow cues to self‐motion in the posterior superior temporal polysensory area	18
Who's on first … Na+, HCO3− or CO32−?	18
Pump up the volume: breathing facilitates cardiac output during exercise by mechanical action	18
Something's fishy: cardiovascular ATP‐sensitive K+ channels in zebrafish	18
Identification of a helix–turn–helix motif for high temperature dependence of vanilloid receptor TRPV2	18
Oncomodulin regulates spontaneous calcium signalling and maturation of afferent innervation in cochlear outer hair cells	18
Single muscle fibre contractile characteristics with lifelong endurance exercise	18
Past questions, present results, future perspectives: Interacting chemosensitive areas and the hypercapnic ventilatory response	18
Function of K2P channels in the mammalian node of Ranvier	18
A systematic review of computational models for the design of spinal cord stimulation therapies: from neural circuits to patient‐specific simulations	17
Exosomes and the cardiovascular system: role in cardiovascular health and disease	17
A detailed mathematical model of the human atrial cardiomyocyte: integration of electrophysiology and cardiomechanics	17
Ageing impairs endothelium‐dependent vasodilatation and alters redox signalling in diaphragm arterioles from male and female Fischer‐344 rats	17
Towards spatially selective efferent neuromodulation: anatomical and functional organization of cardiac fibres in the porcine cervical vagus nerve	17
The effects of local vibration inducing a tonic vibration reflex or movement illusion on acute modulations of corticospinal excitability	17
Muscular strength, endothelial function and cognitive disorders: state of the art	17

Reorganization of mitochondria–organelle interactions during postnatal development in skeletal muscle	17
Ketogenic diet and ketone salts differentially improve cardiometabolic complications in an HFpEF rat model	17
CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative and non‐associative learning	17
Translating physiology of the arterial chemoreflex into novel therapeutic interventions targeting carotid bodies in cardiometabolic disorders	17
The post‐arteriole transitional zone: a specialized capillary region that regulates blood flow within the CNS microvasculature	17
Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse	17
Extracellular vesicles and their microRNA cargo in ischaemic stroke	16
Notch1 promotes ordered revascularization through Semaphorin 3g modulation of downstream vascular patterning signalling factors	16
Enter Sandman: An eye opening opinion of cardiovascular disease prevention in cervical spinal cord injury	16
Issue Information	16
Stem cell approaches for tendon repair: delusion or insight	16
Becoming mindful of mindfulness: a promising approach to reducing sympathetic nervous system overactivity in chronic kidney disease	16
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Oxytocin and corticotropin‐releasing hormone exaggerate nucleus tractus solitarii neuronal and synaptic activity following chronic intermittent hypoxia	16
Cross Talk proposal: Human‐derived brain tissue is a better epilepsy model than animal‐based approaches	16
Physiological mechanisms of unexplained (functional) gastrointestinal disorders	16
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Enhancing stroke risk stratification in atrial fibrillation through non‐Newtonian blood modelling and Gaussian process emulation	16
Endurance exercise training changes the limitation on muscle V̇O2max${\dot{V}}_{{{\mathrm{O}}}_{\mathrm{2}}{\mathrm{max}}}$ in normoxia from the capacity to utilize O2 to the capacity to tr	16
Activating thermogenesis to combat obesity: hot topic or cold front?	16
Channelling protons out of the heart	16
The legacy of A. V. Hill's Nobel Prize winning work on muscle energetics	16
Annual Prize Lecture 2024: Endogenous physiological mechanisms as basis for the treatment of obesity and type 2 diabetes	16
Evolution of rod bipolar cells and rod vision	16
Activation of TRPA1 and TRPM3 triggers Ca2+ waves in central terminals of sensory neurons and facilitates synaptic activity in the spinal dorsal horn	16
The repair capacity spectrum of human skeletal muscle injury from sports to surgical trauma settings	16
Autonomic modulation with mindfulness‐based stress reduction in chronic kidney disease: a randomized controlled trial	16
Recurrence of ventricular fibrillation in out‐of‐hospital cardiac arrest: Clinical evidence and underlying ionic mechanisms	16
Can muscle typology explain the inter‐individual variability in resistance training adaptations?	15
Fluorescent biosensor imaging meets deterministic mathematical modelling: quantitative investigation of signalling compartmentalization	15
When right ventricular pressure meets volume: The impact of arrival time of reflected waves on right ventricle load in pulmonary arterial hypertension	15
Insulin, Nobel laureates and The Journal of Physiology	15
The complex function of macrophages and their subpopulations in metabolic injury associated fatty liver disease	15
A multimodal exercise countermeasure prevents the negative impact of head‐down tilt bed rest on muscle volume and mitochondrial health in older adults	15
Rebuttal from Amy Richardson and Gareth Morris	15
Vaping for two: unravelling the mysteries of E‐cigarettes and fetal vascular health	15
Loss of anoctamin 1 reveals a subtle role for BK channels in lymphatic muscle action potentials	15
What is fetal growth restriction and how might we know?	15
The vascular response to acute hyperglycaemia: What is the role of exercise capacity?	15
Paraventricular nucleus projections to the nucleus tractus solitarii are essential for full expression of hypoxia‐induced peripheral chemoreflex responses	15
Scale‐invariant changes in corticospinal excitability reflect multiplexed oscillations in the motor output	15
Ubiquitin ligase signalling networks shape presynaptic development, function and disease	15
Muscle–fat crosstalk: effects of exercise on brown adipose tissue; what do we know?	15
Beyond the madness: a balanced approach to standardization, practicality and innovation in exercise physiology threshold assessment	15
Homeostasis and evolution in relation to regeneration and repair	15
A narrative review of periodic breathing during sleep at high altitude: From acclimatizing lowlanders to adapted highlanders	15
Comparison of excitation–contraction coupling between Drosophila and vertebrate muscle	15
Exercise affects fatty acid oxidation and lipid droplets in patients with type 2 diabetes	15
Expiratory flow limitation during exercise: why does it ‘suck’ so much?	15
High altitude differentially modulates potassium channel‐evoked vasodilatation in pregnant human myometrial arteries	15
Presynaptic quantal size enhancement counteracts post‐tetanic release depression	15
Fasting and the short‐term consumption of a ketogenic diet are sufficient interventions to protect against OLZ‐induced hyperglycaemia in mice	15
Time course and fibre type‐dependent nature of calcium‐handling protein responses to sprint interval exercise in human skeletal muscle	14
Symptom‐modifying strategy to treat upper respiratory tract infections: a clinical and mechanistic evidence of ColdZyme	14
Mitochondrial function in brain and muscle metabolism: the crucial role during early sensorimotor development	14
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Pedalling toward a deeper understanding of exercise effects on immune function	14
Age‐related diaphragm dysfunction: could diaphragm arteriole dysfunction be to blame?	14
Plasma measurements of the dual sugar test reveal carbohydrate immediately alleviates intestinal permeability caused by exertional heat stress	14
Directional sensitivity of C‐low‐threshold mechanoreceptors: insights from in vivo calcium imaging	14
Ca2+ signalling in interstitial cells of Cajal contributes to generation and maintenance of tone in mouse and monkey lower oesophageal sphincters	14
Phase‐dependent local brain states determine the impact of image‐guided transcranial magnetic stimulation on motor network electroencephalographic synchronization	14
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BK channels at dendritic spines: A mechanism for coupling morphology, plasticity and information storage?	14
The link between sarcopenic obesity and Alzheimer's disease: a brain‐derived neurotrophic factor point of view	14
Neural coordination of bilateral hand movements: evidence for an involvement of brainstem motor centres	14
Cardiac programming in the placentally restricted sheep fetus in early gestation	14
Interstitial cells of Cajal – pacemakers of the gastrointestinal tract	14
Muscle‐derived IL‐1β regulates EcSOD expression via the NBR1‐p62‐Nrf2 pathway in muscle during cancer cachexia	14
Untangling age and menopause: vascular mechanisms for cardiovascular disease risk in females	14
School of ‘hard NOX’ for the ageing artery	14
Functions require junctions: endurance exercise protects from age‐induced alterations of the neuromuscular system	14
Context‐dependent orientation discontinuity encoding by gamma rhythms in mouse primary visual cortex	14
Profoundly lower muscle mass and rate of contractile protein synthesis in boys with Duchenne muscular dystrophy	14
Exercise, healthy ageing, and the potential role of small extracellular vesicles	14
High‐definition transcranial direct‐current stimulation of left primary motor cortices modulates beta and gamma oscillations serving motor control	13
The contribution of age and sex hormones to female neuromuscular function across the adult lifespan	13
Understanding the hypothalamic–brainstem bridge in the hypoxia puzzle	13
Skeletal muscle mitochondria in strength athletes: meeting energy needs with mitochondrial morphological changes	13
Mutation protocols share with sexual reproduction the physiological role of producing genetic variation within ‘constraints that deconstrain’	13
Comprehensive measurement of muscle maximal oxygen uptake determinants: insights and application	13
Acute intermittent hypoxia increases maximal motor unit discharge rates in people with chronic incomplete spinal cord injury	13
Pre‐loading large volume oral electrolytes: tracing fluid and ion fluxes in horses during rest, exercise and recovery	13
Muscle hypertrophic effect of inhaled beta2‐agonist is associated with augmented insulin‐stimulated whole‐body glucose disposal in young men	13
Selective glycinergic input from vGluT3 amacrine cells confers a suppressed‐by‐contrast trigger feature in a subtype of M1 ipRGCs in the mouse retina	13
Early heart and skeletal muscle mitochondrial response to a moderate hypobaric hypoxia environment	13
Sodium appetite and thirst do not require angiotensinogen production in astrocytes or hepatocytes	13
Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals	13
What can insects teach us about hearing loss?	13
Using exercise training to improve glycaemic control and uncover mechanisms of impaired skeletal muscle in type 1 diabetics	13
Cerebral blood flow regulation in hypobaric hypoxia: role of haemoconcentration	13
Active force generation contributes to the complexity of spontaneous activity and to the response to stretch of murine cardiomyocyte cultures	13