OOIR: Observatory of International Research

Papers

(The H4-Index of Life Sciences is 56. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Insights into the development of insulin-producing cells: Precursors correlated involvement of microRNA panels	356
Behavioural disruption in diabetic mice: Neurobiological correlates and influences of dietary α-linolenic acid	329
Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway	324
Targeting GAS6/AXL signaling improves the response to immunotherapy by restoring the anti-immunogenic tumor microenvironment in gastric cancer	213
The combination of mesenchymal stem cell- and hepatocyte-derived exosomes, along with imipenem, ameliorates inflammatory responses and liver damage in a sepsis mouse model	192
Cross-species gene expression patterns of purinergic signaling in the human and mouse trigeminal ganglion	162
The N6-methyladenosine modification in pathologic angiogenesis	159
Coadministration of olanzapine causes minor impacts on the diabetogenic outcomes induced by dexamethasone treatment in rats	143
Pancreastatin inhibitor PSTi8 prevents free fatty acid-induced oxidative stress and insulin resistance by modulating JNK pathway: In vitro and in vivo findings	142
The proteomic landscape of ovarian cancer cells in response to melatonin	142
Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma	142
Optimal intervention time of ADSCs for hepatic ischemia-reperfusion combined with partial resection injury in rats	129
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway	124
The anxiolytic sertraline reduces the impact of psychological stress on bladder function in mice	121
Emerging therapeutic landscape: Incretin agonists in chronic kidney disease management	121
A detailed insight into macrophages' role in shaping lung carcinogenesis	105
The inhibition of autophagy by spautin boosts the anticancer activity of fingolimod in multidrug-resistant hepatocellular carcinoma	100
Ergosterol promotes neurite outgrowth, inhibits amyloid-beta synthesis, and extends longevity: In vitro neuroblastoma and in vivo Caenorhabditis elegans evidence	97
Combined effects of high fat diet and exercise on autophagy in white adipose tissue of mice	88
Carboxyaminotriazole: A bone savior in collagen-induced arthritis—Halting osteoclastogenesis via interleukin-1β downregulation	87
Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach	85
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period	84
Editorial Board	80
The dynamicity of mutant KRAS β2 strand modulates its downstream activation and predicts anticancer KRAS inhibition	79
The combined therapy of mesenchymal stem cell transplantation and resveratrol for diabetes: Future applications and challenges	75

The chromatin remodeling protein BRG1 mediates Ang II induced pro-fibrogenic response in renal fibroblasts	75
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk	70
Myeloid derived suppressor cells and innate immune system interaction in tumor microenvironment	69
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]	69
Sulforaphane regulates Nrf2-mediated antioxidant activity and downregulates TGF-β1/Smad pathways to prevent radiation-induced muscle fibrosis	68
Metacaspase (Pf MCA-1) as antimalarial drug target: An in silico approach and their biological validation	66
Human gestational diabetes mellitus–derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets	66
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress	65
Metabolomics profiling and chemoresistance mechanisms in ovarian cancer cell lines: Implications for targeting glutathione pathway	65
Autophagy deficiency exacerbated hypoxia-reoxygenation induced inflammation and cell death via a mitochondrial DNA/STING/IRF3 pathway	64
Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy	64
Integrin αvβ3 and disulfide bonds play important roles in NGR-retargeted adenovirus transduction efficiency	64
CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia	63
Preclinical metabolic characterization of mefunidone, a novel anti-renal fibrosis drug	63
In vitro assessment of anti-fibrotic drug activity does not predict in vivo efficacy in murine models of Duchenne muscular dystrophy	63
Repurposing therapeutics for malignant pleural mesothelioma (MPM) – Updates on clinical translations and future outlook	62
Effect of folate-targeted Erlotinib loaded human serum albumin nanoparticles on tumor size and survival rate in a rat model of glioblastoma	61
Liraglutide attenuates intestinal ischemia/reperfusion injury via NF-κB and PI3K/Akt pathways in mice	60
Gulf War Illness Clinical Trials and Interventions Consortium (GWICTIC): A collaborative research infrastructure for intervention and implementation	60
Regulation of metabolism by circadian rhythms: Support from time-restricted eating, intestinal microbiota & omics analysis	60
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia	59
Physical health, behavioral and emotional functioning in children of gulf war veterans	58
High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury	58
Antioxidant therapy reverses sympathetic dysfunction, oxidative stress, and hypertension in male hyperadipose rats	58
The C C motif chemokine ligand 11 contributes to alcoholic liver disease	57
Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets	57
Renal protective effects and mechanisms of the angiotensin receptor-neprilysin inhibitor LCZ696 in mice with cardiorenal syndrome	57
Rhein ameliorates septic lung injury and intervenes in macrophage metabolic reprogramming in the inflammatory state by Sirtuin 1	57
6-NitroDopamine is an endogenous modulator of rat heart chronotropism	56
Augmented nephroprotective effect of liraglutide and rabeprazole via inhibition of OCT2 transporter in cisplatin-induced nephrotoxicity in rats	56
Exploring Lin28 proteins: Unravelling structure and functions with emphasis on nervous system malignancies	56
Ivabradine restores tonic cardiovascular autonomic control and reduces tachycardia, hypertension and left ventricular inflammation in post-weaning protein malnourished rats	56
Suppression of PCSK9/NF-kB-dependent pathways by acetate ameliorates cardiac inflammation in a rat model of polycystic ovarian syndrome	56
Spontaneous and familial models of Alzheimer's disease: Challenges and advances in preclinical research	56
Targeting HMG-CoA synthase 2 suppresses tamoxifen-resistant breast cancer growth by augmenting mitochondrial oxidative stress-mediated cell death	56