OOIR: Observatory of International Research

Papers

(The H4-Index of Life Sciences is 56. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
4-PBA rescues hyperoxaluria induced nephrolithiasis by modulating urinary glycoproteins: Cross talk between endoplasmic reticulum, calcium homeostasis and mitochondria	297
WITHDRAWN: SCARA5 regulated by MEG3/miR-141 axis attenuates proliferation, migration and invasion of bladder cancer	289
Progesterone signaling in uterine fibroids: Molecular mechanisms and therapeutic opportunities	267
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]	192
Retraction notice to “Euxanthone suppresses tumor growth and metastasis in colorectal cancer via targeting CIP2A/PP2A pathway” [Life Sci. 209 (2018) 498–506]	180
Retraction notice to “Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases” [Life Sci. 314 (2023) 121325]	176
Retraction notice to “Development of novel HPV therapeutic vaccine constructs based on engineered exosomes and tumor cell lysates” [Life Sci. 340 (2024) 122456]	155
Retraction notice to “Mancozeb-induced genotoxicity and apoptosis in cultured human lymphocytes” [Life Sci. 90/21-22 (2012) 815 - 824]	143
Retraction notice to “Octreotide remits endoplasmic reticulum stress to reduce autophagy of intestinal epithelial cell line Caco-2 via upregulation of miR-101” [Life Sci. 231 (2019) 116551]	133
Retraction notice to “Inhibition of the TGF-β1/Smad signaling pathway protects against cartilage injury and osteoarthritis in a rat model” [Life Sci. 189 (2017) 106–113]	131
Retraction notice to “Methyltransferase-like 1 (METTL1) served as a tumor suppressor in colon cancer by activating 7-methyguanosine (m7G) regulated let-7e miRNA/HMGA2 axis” [Life Sci. 249 (2020) 11748	126
Retraction notice to “KDM4A promotes the growth of non-small cell lung cancer by mediating the expression of Myc via DLX5 through the Wnt/β-catenin signaling pathway” [Life Sci. 262 (2020) 118508]	125
RETRACTED: Empagliflozin and neohesperidin mitigate methotrexate hepatotoxicity via Nrf2/PPARγ/HO-1 signalling initiation and suppression of NF-κB/Keap1/ HSP70/caspase-3 axis in rats	123
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia	117
Pharmacologically induced proteolysis of histone deacetylase-6 attenuates influenza virus replication despite limited anti-tumor effects	117
ClC-5 knockout mitigates angiotensin II-induced hypertension and endothelial dysfunction	116
The C C motif chemokine ligand 11 contributes to alcoholic liver disease	115
Targeting the Neuropilin-1 receptor with Ovatodiolide and progress in using periodontal ligament organoids for COVID-19 research and therapy	114
Acute gene expression changes in the mouse hippocampus following a combined Gulf War toxicant exposure	113
Alda-1 mediates cell senescence and counteracts bone loss in weightlessness through regulating mitophagy	111
Mitigating seizure-induced cognitive deficits in mice induced with pentylenetetrazol by roflumilast through targeting the NLRP3 inflammasome/BDNF/SIRT3 pathway and regulating ferroptosis	103
Targeting the HDAC6/Hint2/MICU1 axis to ameliorate acute liver failure via inhibiting NETosis	84
Anti-Endoglin monoclonal antibody prevents the progression of liver sinusoidal endothelial inflammation and fibrosis in MASH	83
Carboxyaminotriazole: A bone savior in collagen-induced arthritis—Halting osteoclastogenesis via interleukin-1β downregulation	82
Identification of biomarkers associated with macrophage polarization in diabetic cardiomyopathy based on bioinformatics and machine learning approaches	80

Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach	80
Inactivated SARS-CoV-2 induces acute skeletal muscle damage in human K18-hACE2 transgenic mice	79
miR-199a-3p suppresses neuroinflammation by directly targeting MyD88 in a mouse model of bone cancer pain	78
miR-142-3p simultaneously targets HMGA1, HMGA2, HMGB1, and HMGB3 and inhibits tumorigenic properties and in-vivo metastatic potential of human cervical cancer cells	77
AM1241 alleviates myocardial ischemia-reperfusion injury in rats by enhancing Pink1/Parkin-mediated autophagy	77
MiR-142-3p targets HMGA2 and suppresses breast cancer malignancy	77
The impact of a western diet on gut microbiota and circadian rhythm: A comprehensive systematic review of in vivo preclinical evidence	76
Emerging role of tumor microenvironment derived exosomes in therapeutic resistance and metastasis through epithelial-to-mesenchymal transition	76
Probiotics and the microbiota-gut-brain axis in neurodegeneration: Beneficial effects and mechanistic insights	76
Exposure to intrauterine diabetes and post-natal high-fat diet: Effects on the endocrine pancreas of adult rat female pups	74
Nanomedicine in cardiology: Precision drug delivery for enhanced patient outcomes	74
Emerging roles of CD133 in the treatment of gastric cancer, a novel stem cell biomarker and beyond	72
Mechanisms of autophagy and mitophagy in skeletal development, diseases and therapeutics	72
Chlorogenic acid, quercetin, coenzyme Q10 and silymarin modulate Keap1-Nrf2/heme oxygenase-1 signaling in thioacetamide-induced acute liver toxicity	68
Anti-inflammatory effects of 6S-5-methyltetrahydrofolate‐calcium on RAW264.7 cells and zebrafish	68
Predisposed obesity and long-term metabolic diseases from maternal exposure to fine particulate matter (PM2.5) — A review of its effect and potential mechanisms	66
Rational designing of peptide-ligand conjugates-based immunotherapy for the treatment of complicated malaria	65
Deciphering the complex landscape of post-translational modifications on PKM2: Implications in head and neck cancer pathogenesis	65
Retraction notice to “Role of hepatic neuropeptide Y-Y1 receptors in a methionine- cholinedeficient model of non-alcoholic steatohepatitis” [Life Sci. 245 (2020) 117356]	64
Retraction notice to “Ginsenoside Rg1 defenses PC-12 cells against hydrogen peroxide-caused damage via up-regulation of miR-216a-5p” [Life Sci. 236 (2019) 116948]	63
The hydrogen sulfide donor 4-carboxyphenyl-isothiocyanate decreases blood pressure and promotes cardioprotective effect through reduction of oxidative stress and nuclear factor kappa B/matrix metallop	61
Upregulation of miR-222-3p alleviates the symptom of aortic dissection through targeting STAT3	61
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period	61
From symmetry to chaos and back: Understanding and imaging the mechanisms of neural repair after stroke	59
Peripheral to brain and hippocampus crosstalk induced by exercise mediates cognitive and structural hippocampal adaptations	59
Cardioprotective and renoprotective effects of venlafaxine on cisplatin-induced cardiotoxicity and nephrotoxicity in rats	59
Determination of the pathways of potential muscle damage and regeneration in response to acute and long-term swimming exercise in mice	57
Molecular and cellular signalling pathways for promoting neural tissue growth - A tissue engineering approach	56
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk	56
A role of connexin 43 on the drug-induced liver, kidney, and gastrointestinal tract toxicity with associated signaling pathways	56
Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy	56