OOIR: Observatory of International Research

Papers

(The H4-Index of Life Sciences is 57. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma	271
Cross-species gene expression patterns of purinergic signaling in the human and mouse trigeminal ganglion	259
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress	204
Rhein ameliorates septic lung injury and intervenes in macrophage metabolic reprogramming in the inflammatory state by Sirtuin 1	179
A detailed insight into macrophages' role in shaping lung carcinogenesis	117
Editorial Board	116
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period	111
Ablation of Brg1 in fibroblast/myofibroblast lineages attenuates renal fibrosis in mice with diabetic nephropathy	109
The dynamicity of mutant KRAS β2 strand modulates its downstream activation and predicts anticancer KRAS inhibition	107
Ivabradine restores tonic cardiovascular autonomic control and reduces tachycardia, hypertension and left ventricular inflammation in post-weaning protein malnourished rats	107
Dysregulated pancreatic lipid phenotype, inflammation and cellular injury in a chronic ethanol feeding model of hepatic alcohol dehydrogenase-deficient deer mice	91
Metabolomics profiling and chemoresistance mechanisms in ovarian cancer cell lines: Implications for targeting glutathione pathway	87
Unleashing the pathological imprinting of cancer in autoimmunity: Is ZEB1 the answer?	87
Liraglutide attenuates intestinal ischemia/reperfusion injury via NF-κB and PI3K/Akt pathways in mice	85
Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy	84
Effect of folate-targeted Erlotinib loaded human serum albumin nanoparticles on tumor size and survival rate in a rat model of glioblastoma	84
Myeloid derived suppressor cells and innate immune system interaction in tumor microenvironment	84
Ergosterol promotes neurite outgrowth, inhibits amyloid-beta synthesis, and extends longevity: In vitro neuroblastoma and in vivo Caenorhabditis elegans evidence	84
Insights into the development of insulin-producing cells: Precursors correlated involvement of microRNA panels	82
The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells	82
Fluid shear stress facilitates prostate cancer metastasis through Piezo1-Src-YAP axis	82
Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway	81
Encapsulated mesenchymal stem cell-derived exosomes promote optic nerve regeneration and functional recovery in a mouse model of optic nerve crush injury	81
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]	81
The inhibition of autophagy by spautin boosts the anticancer activity of fingolimod in multidrug-resistant hepatocellular carcinoma	80

The N6-methyladenosine modification in pathologic angiogenesis	80
Lung cancer vaccination from concept to reality: A critical review of clinical trials and latest advances	76
Molecular insights into the causal role of TG/IDL in rheumatoid arthritis: Integrating Mendelian randomization and single-cell RNA sequencing	75
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk	73
The chromatin remodeling protein BRG1 mediates Ang II induced pro-fibrogenic response in renal fibroblasts	73
Exploring Lin28 proteins: Unravelling structure and functions with emphasis on nervous system malignancies	73
The role of endoplasmic reticulum aminopeptidases in type 1 diabetes mellitus	72
Mebendazole; from an anti-parasitic drug to a promising candidate for drug repurposing in colorectal cancer	72
Emerging therapeutic landscape: Incretin agonists in chronic kidney disease management	70
Downregulation of CDC42 contributes to pulmonary vascular endothelial hyperpermeability and acute lung injury induced by seawater drowning	70
Human gestational diabetes mellitus–derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets	68
The C C motif chemokine ligand 11 contributes to alcoholic liver disease	67
Application of f-FeNC@GOx cascade enzyme nanomaterials in the healing of infected wounds	67
The combination of mesenchymal stem cell- and hepatocyte-derived exosomes, along with imipenem, ameliorates inflammatory responses and liver damage in a sepsis mouse model	66
Upregulation of miR-222-3p alleviates the symptom of aortic dissection through targeting STAT3	66
Photothermal therapy-mediated autophagy in breast cancer treatment: Progress and trends	65
Suppression of PCSK9/NF-kB-dependent pathways by acetate ameliorates cardiac inflammation in a rat model of polycystic ovarian syndrome	65
Carboxyaminotriazole: A bone savior in collagen-induced arthritis—Halting osteoclastogenesis via interleukin-1β downregulation	64
Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets	64
Progesterone signaling in uterine fibroids: Molecular mechanisms and therapeutic opportunities	63
6-NitroDopamine is an endogenous modulator of rat heart chronotropism	61
Coadministration of olanzapine causes minor impacts on the diabetogenic outcomes induced by dexamethasone treatment in rats	61
Protective role of ellagic acid and taurine against fluoxetine induced hepatotoxic effects on biochemical and oxidative stress parameters, histopathological changes, and gene expressions of IL-1β, NF-	60
Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach	60
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway	59
HDAC11 deficiency improves muscle phenotype in a Duchenne muscular dystrophy murine model by reducing inflammation and fibrosis	59
Repurposing therapeutics for malignant pleural mesothelioma (MPM) – Updates on clinical translations and future outlook	59
CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia	59
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia	58
Metacaspase (Pf MCA-1) as antimalarial drug target: An in silico approach and their biological validation	58
CpG-mediated TLR9 signaling pathway enhances the efficacy of the OprF/PcrV DNA vaccine with cGAS-STING-activating properties	57
Screening strategy using a filamentous fungus model to repurpose drugs for mitochondrial complex I deficiencies	57
Augmented nephroprotective effect of liraglutide and rabeprazole via inhibition of OCT2 transporter in cisplatin-induced nephrotoxicity in rats	57