OOIR: Observatory of International Research

Papers

(The H4-Index of Life Sciences is 56. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach	408
Carboxyaminotriazole: A bone savior in collagen-induced arthritis—Halting osteoclastogenesis via interleukin-1β downregulation	261
Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma	239
Cross-species gene expression patterns of purinergic signaling in the human and mouse trigeminal ganglion	214
Repurposing therapeutics for malignant pleural mesothelioma (MPM) – Updates on clinical translations and future outlook	185
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia	173
Sulforaphane regulates Nrf2-mediated antioxidant activity and downregulates TGF-β1/Smad pathways to prevent radiation-induced muscle fibrosis	166
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress	145
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk	111
The proteomic landscape of ovarian cancer cells in response to melatonin	102
Rhein ameliorates septic lung injury and intervenes in macrophage metabolic reprogramming in the inflammatory state by Sirtuin 1	97
A detailed insight into macrophages' role in shaping lung carcinogenesis	92
Editorial Board	91
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]	89
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period	88
Ablation of Brg1 in fibroblast/myofibroblast lineages attenuates renal fibrosis in mice with diabetic nephropathy	83
Ivabradine restores tonic cardiovascular autonomic control and reduces tachycardia, hypertension and left ventricular inflammation in post-weaning protein malnourished rats	81
The dynamicity of mutant KRAS β2 strand modulates its downstream activation and predicts anticancer KRAS inhibition	78
Behavioural disruption in diabetic mice: Neurobiological correlates and influences of dietary α-linolenic acid	76
Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets	76
Targeting GAS6/AXL signaling improves the response to immunotherapy by restoring the anti-immunogenic tumor microenvironment in gastric cancer	74
Integrin αvβ3 and disulfide bonds play important roles in NGR-retargeted adenovirus transduction efficiency	74
Progesterone signaling in uterine fibroids: Molecular mechanisms and therapeutic opportunities	74
Metacaspase (Pf MCA-1) as antimalarial drug target: An in silico approach and their biological validation	74
Lung cancer vaccination from concept to reality: A critical review of clinical trials and latest advances	72

Targeting HMG-CoA synthase 2 suppresses tamoxifen-resistant breast cancer growth by augmenting mitochondrial oxidative stress-mediated cell death	72
6-NitroDopamine is an endogenous modulator of rat heart chronotropism	72
The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells	71
Tuberous sclerosis complex 2 deficiency in cardiomyocytes exacerbates cardiac remodeling in diabetic mice	70
Encapsulated mesenchymal stem cell-derived exosomes promote optic nerve regeneration and functional recovery in a mouse model of optic nerve crush injury	70
Molecular insights into the causal role of TG/IDL in rheumatoid arthritis: Integrating Mendelian randomization and single-cell RNA sequencing	69
Metabolomics profiling and chemoresistance mechanisms in ovarian cancer cell lines: Implications for targeting glutathione pathway	68
Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway	68
Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7	67
The inhibition of autophagy by spautin boosts the anticancer activity of fingolimod in multidrug-resistant hepatocellular carcinoma	66
The combined therapy of mesenchymal stem cell transplantation and resveratrol for diabetes: Future applications and challenges	65
High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury	64
Autophagy deficiency exacerbated hypoxia-reoxygenation induced inflammation and cell death via a mitochondrial DNA/STING/IRF3 pathway	63
Coadministration of olanzapine causes minor impacts on the diabetogenic outcomes induced by dexamethasone treatment in rats	63
The combination of mesenchymal stem cell- and hepatocyte-derived exosomes, along with imipenem, ameliorates inflammatory responses and liver damage in a sepsis mouse model	62
Emerging therapeutic landscape: Incretin agonists in chronic kidney disease management	62
Dysregulated pancreatic lipid phenotype, inflammation and cellular injury in a chronic ethanol feeding model of hepatic alcohol dehydrogenase-deficient deer mice	61
CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia	61
Human gestational diabetes mellitus–derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets	61
Antioxidant therapy reverses sympathetic dysfunction, oxidative stress, and hypertension in male hyperadipose rats	60
Application of f-FeNC@GOx cascade enzyme nanomaterials in the healing of infected wounds	59
Identification of specific gut microbes and their therapeutic potential in ameliorating systemic lupus erythematosus in a mouse model	59
Role of left and right vagus nerves in linking peripheral adrenergic signals to contextual fear memory	59
Insights into the development of insulin-producing cells: Precursors correlated involvement of microRNA panels	59
The C C motif chemokine ligand 11 contributes to alcoholic liver disease	59
Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy	58
Effect of folate-targeted Erlotinib loaded human serum albumin nanoparticles on tumor size and survival rate in a rat model of glioblastoma	57
The role of endoplasmic reticulum aminopeptidases in type 1 diabetes mellitus	56
Mitochondrial transfer in the progression and treatment of cardiac disease	56
Liraglutide attenuates intestinal ischemia/reperfusion injury via NF-κB and PI3K/Akt pathways in mice	56
Photothermal therapy-mediated autophagy in breast cancer treatment: Progress and trends	56
Unleashing the pathological imprinting of cancer in autoimmunity: Is ZEB1 the answer?	56
Combined effects of high fat diet and exercise on autophagy in white adipose tissue of mice	56