Life Sciences

Article	Citations
4-PBA rescues hyperoxaluria induced nephrolithiasis by modulating urinary glycoproteins: Cross talk between endoplasmic reticulum, calcium homeostasis and mitochondria	297
WITHDRAWN: SCARA5 regulated by MEG3/miR-141 axis attenuates proliferation, migration and invasion of bladder cancer	289
Progesterone signaling in uterine fibroids: Molecular mechanisms and therapeutic opportunities	267
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]	192
Retraction notice to “Euxanthone suppresses tumor growth and metastasis in colorectal cancer via targeting CIP2A/PP2A pathway” [Life Sci. 209 (2018) 498–506]	180
Retraction notice to “Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases” [Life Sci. 314 (2023) 121325]	176
Retraction notice to “Development of novel HPV therapeutic vaccine constructs based on engineered exosomes and tumor cell lysates” [Life Sci. 340 (2024) 122456]	155
Retraction notice to “Mancozeb-induced genotoxicity and apoptosis in cultured human lymphocytes” [Life Sci. 90/21-22 (2012) 815 - 824]	143
Retraction notice to “Octreotide remits endoplasmic reticulum stress to reduce autophagy of intestinal epithelial cell line Caco-2 via upregulation of miR-101” [Life Sci. 231 (2019) 116551]	133
Retraction notice to “Inhibition of the TGF-β1/Smad signaling pathway protects against cartilage injury and osteoarthritis in a rat model” [Life Sci. 189 (2017) 106–113]	131
Retraction notice to “Methyltransferase-like 1 (METTL1) served as a tumor suppressor in colon cancer by activating 7-methyguanosine (m7G) regulated let-7e miRNA/HMGA2 axis” [Life Sci. 249 (2020) 11748	126
Retraction notice to “KDM4A promotes the growth of non-small cell lung cancer by mediating the expression of Myc via DLX5 through the Wnt/β-catenin signaling pathway” [Life Sci. 262 (2020) 118508]	125
RETRACTED: Empagliflozin and neohesperidin mitigate methotrexate hepatotoxicity via Nrf2/PPARγ/HO-1 signalling initiation and suppression of NF-κB/Keap1/ HSP70/caspase-3 axis in rats	123
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia	117
Pharmacologically induced proteolysis of histone deacetylase-6 attenuates influenza virus replication despite limited anti-tumor effects	117
ClC-5 knockout mitigates angiotensin II-induced hypertension and endothelial dysfunction	116
The C C motif chemokine ligand 11 contributes to alcoholic liver disease	115
Targeting the Neuropilin-1 receptor with Ovatodiolide and progress in using periodontal ligament organoids for COVID-19 research and therapy	114
Acute gene expression changes in the mouse hippocampus following a combined Gulf War toxicant exposure	113
Alda-1 mediates cell senescence and counteracts bone loss in weightlessness through regulating mitophagy	111
Mitigating seizure-induced cognitive deficits in mice induced with pentylenetetrazol by roflumilast through targeting the NLRP3 inflammasome/BDNF/SIRT3 pathway and regulating ferroptosis	103
Targeting the HDAC6/Hint2/MICU1 axis to ameliorate acute liver failure via inhibiting NETosis	84
Anti-Endoglin monoclonal antibody prevents the progression of liver sinusoidal endothelial inflammation and fibrosis in MASH	83
Carboxyaminotriazole: A bone savior in collagen-induced arthritis—Halting osteoclastogenesis via interleukin-1β downregulation	82
Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach	80

Identification of biomarkers associated with macrophage polarization in diabetic cardiomyopathy based on bioinformatics and machine learning approaches	80
Inactivated SARS-CoV-2 induces acute skeletal muscle damage in human K18-hACE2 transgenic mice	79
miR-199a-3p suppresses neuroinflammation by directly targeting MyD88 in a mouse model of bone cancer pain	78
AM1241 alleviates myocardial ischemia-reperfusion injury in rats by enhancing Pink1/Parkin-mediated autophagy	77
MiR-142-3p targets HMGA2 and suppresses breast cancer malignancy	77
miR-142-3p simultaneously targets HMGA1, HMGA2, HMGB1, and HMGB3 and inhibits tumorigenic properties and in-vivo metastatic potential of human cervical cancer cells	77
The impact of a western diet on gut microbiota and circadian rhythm: A comprehensive systematic review of in vivo preclinical evidence	76
Emerging role of tumor microenvironment derived exosomes in therapeutic resistance and metastasis through epithelial-to-mesenchymal transition	76
Probiotics and the microbiota-gut-brain axis in neurodegeneration: Beneficial effects and mechanistic insights	76
Exposure to intrauterine diabetes and post-natal high-fat diet: Effects on the endocrine pancreas of adult rat female pups	74
Nanomedicine in cardiology: Precision drug delivery for enhanced patient outcomes	74
Emerging roles of CD133 in the treatment of gastric cancer, a novel stem cell biomarker and beyond	72
Mechanisms of autophagy and mitophagy in skeletal development, diseases and therapeutics	72
Chlorogenic acid, quercetin, coenzyme Q10 and silymarin modulate Keap1-Nrf2/heme oxygenase-1 signaling in thioacetamide-induced acute liver toxicity	68
Anti-inflammatory effects of 6S-5-methyltetrahydrofolate‐calcium on RAW264.7 cells and zebrafish	68
Predisposed obesity and long-term metabolic diseases from maternal exposure to fine particulate matter (PM2.5) — A review of its effect and potential mechanisms	66
Rational designing of peptide-ligand conjugates-based immunotherapy for the treatment of complicated malaria	65
Deciphering the complex landscape of post-translational modifications on PKM2: Implications in head and neck cancer pathogenesis	65
Retraction notice to “Role of hepatic neuropeptide Y-Y1 receptors in a methionine- cholinedeficient model of non-alcoholic steatohepatitis” [Life Sci. 245 (2020) 117356]	64
Retraction notice to “Ginsenoside Rg1 defenses PC-12 cells against hydrogen peroxide-caused damage via up-regulation of miR-216a-5p” [Life Sci. 236 (2019) 116948]	63
The hydrogen sulfide donor 4-carboxyphenyl-isothiocyanate decreases blood pressure and promotes cardioprotective effect through reduction of oxidative stress and nuclear factor kappa B/matrix metallop	61
Upregulation of miR-222-3p alleviates the symptom of aortic dissection through targeting STAT3	61
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period	61
From symmetry to chaos and back: Understanding and imaging the mechanisms of neural repair after stroke	59
Peripheral to brain and hippocampus crosstalk induced by exercise mediates cognitive and structural hippocampal adaptations	59
Cardioprotective and renoprotective effects of venlafaxine on cisplatin-induced cardiotoxicity and nephrotoxicity in rats	59
Determination of the pathways of potential muscle damage and regeneration in response to acute and long-term swimming exercise in mice	57
Molecular and cellular signalling pathways for promoting neural tissue growth - A tissue engineering approach	56
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk	56
A role of connexin 43 on the drug-induced liver, kidney, and gastrointestinal tract toxicity with associated signaling pathways	56
Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy	56
L-Histidine attenuates NEFA-induced inflammatory responses by suppressing Gab2 expression	54
Role of the lectin-like domain of thrombomodulin in septic cardiomyopathy	54
Early life stress exacerbates obesity in adult female mice via mineralocorticoid receptor-dependent increases in adipocyte triglyceride and glycerol content	53
Silymarin nanoliposomes attenuate renal injury on diabetic nephropathy rats via co-suppressing TGF-β/Smad and JAK2/STAT3/SOCS1 pathway	53
Rational design and evaluation of GLP-1 derivative for treating hyperglycemia combined with overexercise-induced myocardial injury	53
Hypothalamic anorexigenic signaling pathways (leptin, amylin, and proopiomelanocortin) are semaglutide (GLP-1 analog) targets in obesity control in mice	52
ERK and p38 MAPK inhibition controls NF-E2 degradation and profibrotic signaling in renal proximal tubule cells	52
NP202 treatment improves left ventricular systolic function and attenuates pathological remodelling following chronic myocardial infarction	52
Editorial Board	52
Maternal high fructose diet exacerbates white adipose tissue thermogenic process in offspring upon exposure to cold temperature	52
Targeting multiple disease hallmarks using a synergistic disease-modifying drug combination ameliorates osteoarthritis via inhibition of senescence and inflammation	52
Metabolomics profiling and chemoresistance mechanisms in ovarian cancer cell lines: Implications for targeting glutathione pathway	52
Beta-lapachone ameliorates the progression of primary sclerosing cholangitis pathogenesis in rodent models	51
The chromatin remodeling protein BRG1 mediates Ang II induced pro-fibrogenic response in renal fibroblasts	50
Overview of tumor immunotherapy based on approved drugs	50
Editorial Board	50
Inhibitory effects of naringenin on estrogen deficiency-induced obesity via regulation of mitochondrial dynamics and AMPK activation associated with white adipose tissue browning	49
Editorial Board	49
Comprehensive pan-cancer analysis identifies the RNA-binding protein LRPPRC as a novel prognostic and immune biomarker	49

Cardiac lipidomic profiles in mice undergo changes from fetus to adult	49
Human gestational diabetes mellitus–derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets	49
Calcium sensing receptor: A promising therapeutic target in pulmonary hypertension	49
Essential role of Nrf2 in sulforaphane-induced protection against angiotensin II-induced aortic injury	48
Novel small molecular inhibitor of Pit-Oct-Unc transcription factor 1 suppresses hepatocellular carcinoma cell proliferation	48
Combinatorial effects of melatonin and paclitaxel differ depending on the treatment scheme in colorectal cancer in vitro	47
15-keto-Prostaglandin E2 exhibits bioactive role by modulating glomerular cytoarchitecture through EP2/EP4 receptors	47
The dynamicity of mutant KRAS β2 strand modulates its downstream activation and predicts anticancer KRAS inhibition	47
Role of CRISPR/Cas9 in the treatment of Duchenne muscular dystrophy and its delivery strategies	47
Could gene therapy cure HIV?	46
Editorial Board	46
Production of human embryonic kidney 293T cells stably expressing C-X-C chemokine receptor type 4 (CXCR4) as a screening tool for anticancer lead compound targeting CXCR4	46
Identification of EPZ004777 and FG2216 as inhibitors of TGF-β1 induced Treg cells by screening a library of epigenetic compounds	46
Editorial Board	46
Raptor knockdown concurrently increases the electrical resistance and paracellular permeability of Caco-2 cell monolayers	46
Optimization design of sialic acid derivatives enhances the performance of liposomes for modulating immunosuppressive tumor microenvironments	46
Editorial Board	45
Editorial Board	45
The combined therapy of mesenchymal stem cell transplantation and resveratrol for diabetes: Future applications and challenges	45
Hepatic protein tyrosine phosphatase Shp2 disruption mitigates the adverse effects of ethanol in the liver by modulating oxidative stress and ERK signaling	44
Editorial Board	44
Investigation of time-dependent alterations in adipokine levels and endoplasmic reticulum stress markers in obese patients with laparoscopic sleeve gastrectomy	44
Anti-cancer effect of COVID-19 vaccines in mice models	43
An integrated pan-cancer assessment of prognosis, immune infiltration, and immunotherapy response for B7 family using multi-omics data	43
Role of long non-coding RNAs on the regulation of Nrf2 in chronic diseases	43
Editorial Board	42
The relationship between Gulf War Illness symptom severity and heart rate variability: A pilot study	42
The potential of B7-H6 as a therapeutic target in cancer immunotherapy	42
Sulforaphane regulates Nrf2-mediated antioxidant activity and downregulates TGF-β1/Smad pathways to prevent radiation-induced muscle fibrosis	42
Highland barley attenuates high fat and cholesterol diet induced hyperlipidemia in mice revealed by 16S rRNA gene sequencing and untargeted metabolomics	42
Valsartan as a prophylactic treatment against breast cancer development and niche activation: What molecular sequels follow chronic AT-1R blockade?	42
Tumor-derived nanovesicles enhance cancer synergistic chemo-immunotherapy by promoting cGAS/STING pathway activation and immunogenetic cell death	42
RETRACTED: microRNA-6785-5p-loaded human umbilical cord mesenchymal stem cells-derived exosomes suppress angiogenesis and metastasis in gastric cancer via INHBA	41
CRISPR innovations in tissue engineering and gene editing	41
Betulin prevents high fat diet-induced non-alcoholic fatty liver disease by mitigating oxidative stress and upregulating Nrf2 and SIRT1 in rats	41
Stem cells therapeutic effect in a reserpine-induced fibromyalgia rat model: A possible NLRP3 inflammasome modulation with neurogenesis promotion in the cerebral cortex	41
Molecular docking, synthesis and anticancer activity of thiosemicarbazone derivatives against MCF-7 human breast cancer cell line	41
The molecular targets of taurine confer anti-hyperlipidemic effects	41
High fat suppresses SOD1 activity by reducing copper chaperone for SOD1 associated with neurodegeneration and memory decline	41
The intestinal epithelial-macrophage-crypt stem cell axis plays a crucial role in regulating and maintaining intestinal homeostasis	41
Polydatin ameliorates inflammation and oxidative stress associated with MSU-induced gouty arthritis in mice by regulating PPAR-γ and ferritin activation	40
Arbutin ameliorates hyperglycemia, dyslipidemia and oxidative stress and modulates adipocytokines and PPARγ in high-fat diet/streptozotocin-induced diabetic rats	40
The protective role of two oxindole derivatives is mediated by modulating NLRP3/caspase-1 and PI3K/AKT pathways in a preclinical animal model of hepatic ischemia reperfusion injury	40
Retraction notice to “EPO protects mesenchymal stem cells from hyperglycaemic injury via activation of the Akt/FoxO3a pathway” [Life Sci. 222 (2019) 158–167]	40
Echocardiographic evaluation of cardiac reserve to detect subtle cardiac dysfunction in mice	40
Taurohyodeoxycholic acid alleviates trinitrobenzene sulfonic acid induced ulcerative colitis via regulating Th1/Th2 and Th17/Treg cells balance	40
Retraction notice to “TRAF2 gene silencing induces proliferation and represses apoptosis of nucleus pulposus cells in rats with intervertebral disc degeneration” [Life Sci. 279 (2021) 119670]	40
Immunomodulatory potential of human clonal mesenchymal stem cells and their extracellular vesicle subpopulations in an inflammatory-mediated diabetic Rhesus monkey model	40
Unleashing the pathological imprinting of cancer in autoimmunity: Is ZEB1 the answer?	40
Retraction notice to “Hepatocellular carcinoma cells-derived exosomal microRNA-378b enhances hepatocellular carcinoma angiogenesis” [Life Sci. 273 (2021) 119184]	39
Role of glucocorticoid receptor (GR) in white adipose tissue beiging	39
Reserpine and PCPA reduce heat tolerance in Drosophila melanogaster	39
Chronic administration of catalase inhibitor attenuates hypertension in renovascular hypertensive rats	39
GABAB receptor activation alters astrocyte phenotype changes induced by trimethyltin via ERK signaling in the dentate gyrus of mice	39
Navigating therapeutic prospects by modulating autophagy in colorectal cancer	38
Modulatory effects of carvacrol against cadmium-induced hepatotoxicity and nephrotoxicity by molecular targeting regulation	38
The many faces of DGAT1	38
Epigenetics as a strategic intervention for early diagnosis and combatting glycolyis-induced chemoresistance in gynecologic cancers	38
The mechanism of acetylation-mediated fusion of lysosomes with autophagosomes in neurons after ischemic stroke	38
The effect of conditioned medium from human amniotic membrane-derived mesenchymal stem cells on thymus involution	38
Roles of long non-coding RNAs in angiogenesis-related diseases: Focusing on non-neoplastic aspects	38
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway	38
The hybrid immunity defined by weaker immune imprinting of people living with HIV has a stronger neutralizing response against Omicron variants. A suggested explanation for fewer symptoms in people li	37
Formononetin alleviates no reflow after myocardial ischemia-reperfusion via modulation of gut microbiota to inhibit inflammation	37
The modulation of cholecystokinin receptor 1 in the NAc core input from VTA on METH-induced CPP acquisition	37
Emerging insights on the role of Elovl6 in human diseases: Therapeutic challenges and opportunities	37
The RNA-binding protein CMSS1 promotes the progression of non-small cell lung cancer by regulating the telomerase protein subunit hTERT	37
Effects of serotonergic manipulation in the brainstem and hypothalamus of overnourished rats during lactation	37
Gestational hypoxia elicits long-term cardiovascular dysfunction in female guinea pigs	37
Combined effects of high fat diet and exercise on autophagy in white adipose tissue of mice	36
Comparative effects of finasteride and laser-irradiated silver nanoparticles on testicular function and histology in testosterone induced benign prostatic hyperplasia in rats	36
Glibenclamide promotes FGF21 secretion in interscapular BAT and attenuates depression-like behaviors in male mice with HFD-induced obesity	36
Piperine mitigates aortic vasculopathy in streptozotocin-diabetic rats via targeting TXNIP-NLRP3 signaling	36
Corrigendum to “Activation of androgen receptors alters hippocampal synaptic plasticity and memory retention through modulation of L-type calcium channels” [Life Sci. 314 (2023) 121155]	36
High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury	36
Therapeutic implications of targeting autophagy and TGF-β crosstalk for the treatment of liver fibrosis	36
Targeting HMG-CoA synthase 2 suppresses tamoxifen-resistant breast cancer growth by augmenting mitochondrial oxidative stress-mediated cell death	35
Expression of concern: Involvement of mitogen-activated protein kinases (MAPKs) during testicular ischemia–reperfusion injury in nuclear factor-κB knock-out mice [Life Sci. 81 (2007) 413–422]	35
Corrigendum to “Alfuzosin ameliorates diabetes by boosting PGK1 activity in diabetic mice” [Life Sci. 317 (2023) 121491]	35
Spontaneous and familial models of Alzheimer's disease: Challenges and advances in preclinical research	35

Diosmetin alleviates S. aureus-induced mastitis by inhibiting SIRT1/GPX4 mediated ferroptosis	35
Cyclic-AMP response element binding protein (CREB) and microRNA miR-29b regulate renalase gene expression under catecholamine excess conditions	35
Natural Killer T cells and the invariant subset promote atherosclerosis: A meta-analysis	35
Corrigendum to “PPAR-α knockout leads to elevated blood pressure response to angiotensin II infusion associated with an increase in renal α-1 Na+/K+ ATPase protein expression and activity” [Life Sci.,	35
Optimization of the cotransfection of SERCA2a and Cx43 genes for myocardial infarction complications	35
Sex-specificities in offspring neurodevelopment and behaviour upon maternal glycation: Putative underlying neurometabolic and synaptic changes	35
The regulation of protein acetylation influences the redox homeostasis to protect the heart	34
Editorial Board	34
Megalin, a multi-ligand endocytic receptor, and its participation in renal function and diseases: A review	34
Choline kinase: An underappreciated rheumatoid arthritis therapeutic target	34
A novel signature of autophagy-related immunophenotyping biomarkers in osteoarthritis	34
Inhibition of FGFR2 enhances chemosensitivity to gemcitabine in cholangiocarcinoma through the AKT/mTOR and EMT signaling pathways	34
GALNT2 promotes cell proliferation, migration, and invasion by activating the Notch/Hes1-PTEN-PI3K/Akt signaling pathway in lung adenocarcinoma	34
Insights into the role of P2X7R/DUSP6/ERK1/2 and SIRT2/MDM2 signaling in the nephroprotective effect of berberine against cisplatin-induced renal fibrosis in rats	34
Acetylcholine receptor agonists effectively attenuated multiple program cell death pathways and improved left ventricular function in trastuzumab-induced cardiotoxicity in rats	34
The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells	34
Ruxolitinib attenuates experimental autoimmune encephalomyelitis (EAE) development as animal models of multiple sclerosis (MS)	34
Decrease of KATP channel expression through D3 receptor-mediated GSK3β signaling alleviates levodopa-induced dyskinesia (LID) in Parkinson's disease mouse model	33
Quercetin potentiates the hepatoprotective effect of sildenafil and/or pentoxifylline against intrahepatic cholestasis: Role of Nrf2/ARE, TLR4/NF-κB, and NLRP3/IL-1β signaling pathways	33
Effects of voluntary exercise duration on myocardial ischaemic tolerance, kinase signaling and gene expression	33
Epitalon-activated telomerase enhance bovine oocyte maturation rate and post-thawed embryo development	33
Editorial Board	33
MiR-21-3p in extracellular vesicles from vascular fibroblasts of spontaneously hypertensive rat promotes proliferation and migration of vascular smooth muscle cells	33
Estrogen cholestasis induces gut and liver injury in rats involving in activating PI3K/Akt and MAPK signaling pathways	33
Molecular pathways and role of epigenetics in the idiopathic pulmonary fibrosis	33
Nanotherapeutics in the treatment of acute respiratory distress syndrome	33
Boston biorepository, recruitment and integrative network (BBRAIN): A resource for the Gulf War Illness scientific community	32
Involvement of mitogen-activated protein kinase (MAPK)-activated protein kinase 2 (MK2) in endothelial dysfunction associated with pulmonary hypertension	32
Angiotensin 1–7 mitigates rhabdomyolysis induced renal injury in rats via modulation of TLR-4/NF-kB/iNOS and Nrf-2/heme‑oxygenase-1 signaling pathways	32
Regulation of IL-6/STAT-3/Wnt axis by nifuroxazide dampens colon ulcer in acetic acid-induced ulcerative colitis model: Novel mechanistic insight	32
Transplantation of bone marrow mesenchymal stem cells and fibrin glue into extraction socket in maxilla promoted bone regeneration in osteoporosis rat	32
Colorectal cancer cell-derived extracellular vesicles transfer miR-221-3p to promote endothelial cell angiogenesis via targeting suppressor of cytokine signaling 3	32
Research tool for classifying Gulf War illness using survey responses: Lessons for writing replicable algorithms for symptom-based conditions	32
Effect of bempedoic acid on angiotensin-II induced hypertension and vascular tissue remodelling in renal hypertensive rats through AMPK multiple signalling pathways modulation	32
Lipid peroxidation and liver damage in double and simple common bile duct ligation models in male Sprague-Dawley rats	32
Renal artery responses to trace amines: Multiple and differential mechanisms of action	32
Metacaspase (Pf MCA-1) as antimalarial drug target: An in silico approach and their biological validation	32
Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice	31
The roles of gut microbiome and metabolites associated with skin photoaging in mice by intestinal flora sequencing and metabolomics	31
Overview of key molecular and pharmacological targets for diabetes and associated diseases	31
Gold nanoparticles show potential in vitro antiviral and anticancer activity	31
Prognostic value of immune-related cells and genes in the tumor microenvironment of ovarian cancer, especially CST4	31
Vitamin B1 and calcitriol enhance glibenclamide suppression of diabetic nephropathy: Role of HMGB1/TLR4/NF-κB/TNF-α/Nrf2/α-SMA trajectories	31
10-Dehydrogingerdione ameliorates renal endoplasmic reticulum/oxidative stress and apoptosis in alcoholic nephropathy induced in experimental rats	31
Non-invasive biomarkers of acute rejection in pediatric kidney transplantation: New targets and strategies	31
Hydrogen sulfide reduces pyroptosis and alleviates ischemia-reperfusion-induced acute kidney injury by inhibiting NLRP3 inflammasome	31
Evaluation of isoeugenol in inhibition of Staphylococcus aureus efflux pumps and their toxicity using Drosophila melanogaster model	31
Differentiation-inducing factor-1 reduces lipopolysaccharide-induced vascular cell adhesion molecule-1 by suppressing mTORC1-S6K signaling in vascular endothelial cells	31
Short-term but not long-term high fat diet feeding protects against pressure overload-induced heart failure through activation of mitophagy	31
Gulf War Illness Clinical Trials and Interventions Consortium (GWICTIC): A collaborative research infrastructure for intervention and implementation	31
Bone marrow mesenchymal stem cell-derived extracellular vesicles containing miR-497-5p inhibit RSPO2 and accelerate OPLL	31
The anxiolytic sertraline reduces the impact of psychological stress on bladder function in mice	31
O-linked N-acetylglucosaminyltransferase OGT inhibits diabetic nephropathy by stabilizing histone methyltransferases EZH2 via the HES1/PTEN axis	31
Sevoflurane inhibits ferroptosis: A new mechanism to explain its protective role against lipopolysaccharide-induced acute lung injury	31
A multidisciplinary approach to assessment and management of long COVID cognitive concerns	31
Galectin-3 participates in PASMC migration and proliferation by interacting with TGF-β1	30
Laser-induced singlet oxygen selectively triggers oscillatory mitochondrial permeability transition and apoptosis in melanoma cell lines	30
Augmented nephroprotective effect of liraglutide and rabeprazole via inhibition of OCT2 transporter in cisplatin-induced nephrotoxicity in rats	30
Semaphorins and its receptors: Emerging cellular biomarkers and therapeutic targets in autoimmune and inflammatory disorders	30
Exploring the role of exosomes in the pathogenesis and treatment of cardiomyopathies: A comprehensive literature review	30
Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma	30
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis	30
A detailed insight into macrophages' role in shaping lung carcinogenesis	30
The development of a human Brucella mucosal vaccine: What should be considered?	30
Food preference-based screening method for identification of effectors of substance use disorders using Caenorhabditis elegans	30
Ketogenic diet restores hormonal, apoptotic/proliferative balance and enhances the effect of metformin on a letrozole-induced polycystic ovary model in rats	30
Oleuropin controls miR-194/XIST/PD-L1 loop in triple negative breast cancer: New role of nutri-epigenetics in immune-oncology	30
Biological processes and key druggable targets involved in age-associated memory loss: A systematic review	30
Tissue-derived extracellular vesicles: Isolation, purification, and multiple roles in normal and tumor tissues	30
GLP-1 and IL-6 regulates obesity in the gut and brain	30
SETD3 functions beyond histidine methylation	30
Phosphodiesterase 4 inhibition restrains muscle proteolysis in diabetic rats by activating PKA and EPAC/Akt effectors and inhibiting FoxO factors	30
The anti-tumor effects of CT-26 derived exosomes enriched by MicroRNA-34a on murine model of colorectal cancer	29
Distinct effects of growth hormone deficiency and disruption of hypothalamic kisspeptin system on reproduction of male mice	29
Pan-cancer analysis and experiments with cell lines reveal that the slightly elevated expression of DLGAP5 is involved in clear cell renal cell carcinoma progression	29
Tirzepatide, a dual agonist of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), positively impacts the altered microbiota of obese, diabetic, ovariectomized mice	29
Itraconazole and neutrophil interactions in the immune-inflammatory response of paracoccidioidomycosis using a murine air pouch infection model	29
The nucleocapsid protein of zoonotic betacoronaviruses is an attractive target for antiviral drug discovery	29
Integrin αvβ3 and disulfide bonds play important roles in NGR-retargeted adenovirus transduction efficiency	29
Vaping/e-cigarette-induced pulmonary extracellular vesicles contribute to exacerbated cardiomyocyte impairment through the translocation of ERK5	29
Resistance exercise shifts the balance of renin-angiotensin system toward ACE2/Ang 1–7 axis and reduces inflammation in the kidney of diabetic rats	29
The protective effect of Escherichia coli Nissle 1917 on the intestinal barrier is mediated by inhibition of RhoA/ROCK2/MLC signaling via TLR-4	29
Role of melatonin mediated G-CSF induction in hematopoietic system of gamma-irradiated mice	29
Ferulic acid positively modulates the inflammatory response to septic liver injury through the GSK-3β/NF-κB/CREB pathway	29
SLC35E2 promoter mutation as a prognostic marker of esophageal squamous cell carcinoma	29
Cardiac-specific Suv39h1 knockout ameliorates high-fat diet induced diabetic cardiomyopathy via regulating Hmox1 transcription	29
Flavonoids as regulators of TIMPs expression in cancer: Consequences, opportunities, and challenges	29
Acid-sensing ion channel 1 in nucleus tractus solitarii neurons contributes to the enhanced CO2-stimulated cardiorespiratory effect in spontaneously hypertensive rats	28
Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7	28
Intragastric botulinum toxin injection directly regulates ghrelin expression via reactive oxygen species and NF-κB signaling	28
Regulation of TGF-β/BMP signaling during osteoblast development by non-coding RNAs: Potential therapeutic applications	28
Gentisic acid ameliorates type 2 diabetes induced by Nicotinamide-Streptozotocin in male mice by attenuating pancreatic oxidative stress and inflammation through modulation of Nrf2 and NF-кB pathways	28
Modulating ferroptosis and mycobactericidal activity in lung epithelial cells via YY1/iNOS pathway	28
RETRACTED: Blocking ATP-P1Rs axis attenuate alcohol-related liver fibrosis	28
High salt aggravates renal inflammation via promoting pro-inflammatory macrophage in 5/6-nephrectomized rat	28