Life Sciences

Article	Citations
Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach	408
Carboxyaminotriazole: A bone savior in collagen-induced arthritis—Halting osteoclastogenesis via interleukin-1β downregulation	261
Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma	239
Cross-species gene expression patterns of purinergic signaling in the human and mouse trigeminal ganglion	214
Repurposing therapeutics for malignant pleural mesothelioma (MPM) – Updates on clinical translations and future outlook	185
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia	173
Sulforaphane regulates Nrf2-mediated antioxidant activity and downregulates TGF-β1/Smad pathways to prevent radiation-induced muscle fibrosis	166
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress	145
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk	111
The proteomic landscape of ovarian cancer cells in response to melatonin	102
Rhein ameliorates septic lung injury and intervenes in macrophage metabolic reprogramming in the inflammatory state by Sirtuin 1	97
A detailed insight into macrophages' role in shaping lung carcinogenesis	92
Editorial Board	91
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]	89
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period	88
Ablation of Brg1 in fibroblast/myofibroblast lineages attenuates renal fibrosis in mice with diabetic nephropathy	83
Ivabradine restores tonic cardiovascular autonomic control and reduces tachycardia, hypertension and left ventricular inflammation in post-weaning protein malnourished rats	81
The dynamicity of mutant KRAS β2 strand modulates its downstream activation and predicts anticancer KRAS inhibition	78
Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets	76
Behavioural disruption in diabetic mice: Neurobiological correlates and influences of dietary α-linolenic acid	76
Progesterone signaling in uterine fibroids: Molecular mechanisms and therapeutic opportunities	74
Metacaspase (Pf MCA-1) as antimalarial drug target: An in silico approach and their biological validation	74
Targeting GAS6/AXL signaling improves the response to immunotherapy by restoring the anti-immunogenic tumor microenvironment in gastric cancer	74
Integrin αvβ3 and disulfide bonds play important roles in NGR-retargeted adenovirus transduction efficiency	74
Targeting HMG-CoA synthase 2 suppresses tamoxifen-resistant breast cancer growth by augmenting mitochondrial oxidative stress-mediated cell death	72

6-NitroDopamine is an endogenous modulator of rat heart chronotropism	72
Lung cancer vaccination from concept to reality: A critical review of clinical trials and latest advances	72
The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells	71
Tuberous sclerosis complex 2 deficiency in cardiomyocytes exacerbates cardiac remodeling in diabetic mice	70
Encapsulated mesenchymal stem cell-derived exosomes promote optic nerve regeneration and functional recovery in a mouse model of optic nerve crush injury	70
Molecular insights into the causal role of TG/IDL in rheumatoid arthritis: Integrating Mendelian randomization and single-cell RNA sequencing	69
Metabolomics profiling and chemoresistance mechanisms in ovarian cancer cell lines: Implications for targeting glutathione pathway	68
Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway	68
Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7	67
The inhibition of autophagy by spautin boosts the anticancer activity of fingolimod in multidrug-resistant hepatocellular carcinoma	66
The combined therapy of mesenchymal stem cell transplantation and resveratrol for diabetes: Future applications and challenges	65
High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury	64
Autophagy deficiency exacerbated hypoxia-reoxygenation induced inflammation and cell death via a mitochondrial DNA/STING/IRF3 pathway	63
Coadministration of olanzapine causes minor impacts on the diabetogenic outcomes induced by dexamethasone treatment in rats	63
Emerging therapeutic landscape: Incretin agonists in chronic kidney disease management	62
The combination of mesenchymal stem cell- and hepatocyte-derived exosomes, along with imipenem, ameliorates inflammatory responses and liver damage in a sepsis mouse model	62
CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia	61
Human gestational diabetes mellitus–derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets	61
Dysregulated pancreatic lipid phenotype, inflammation and cellular injury in a chronic ethanol feeding model of hepatic alcohol dehydrogenase-deficient deer mice	61
Antioxidant therapy reverses sympathetic dysfunction, oxidative stress, and hypertension in male hyperadipose rats	60
Role of left and right vagus nerves in linking peripheral adrenergic signals to contextual fear memory	59
Insights into the development of insulin-producing cells: Precursors correlated involvement of microRNA panels	59
The C C motif chemokine ligand 11 contributes to alcoholic liver disease	59
Application of f-FeNC@GOx cascade enzyme nanomaterials in the healing of infected wounds	59
Identification of specific gut microbes and their therapeutic potential in ameliorating systemic lupus erythematosus in a mouse model	59
Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy	58
Effect of folate-targeted Erlotinib loaded human serum albumin nanoparticles on tumor size and survival rate in a rat model of glioblastoma	57
Photothermal therapy-mediated autophagy in breast cancer treatment: Progress and trends	56
Unleashing the pathological imprinting of cancer in autoimmunity: Is ZEB1 the answer?	56
Combined effects of high fat diet and exercise on autophagy in white adipose tissue of mice	56
The role of endoplasmic reticulum aminopeptidases in type 1 diabetes mellitus	56
Mitochondrial transfer in the progression and treatment of cardiac disease	56
Liraglutide attenuates intestinal ischemia/reperfusion injury via NF-κB and PI3K/Akt pathways in mice	56
The N6-methyladenosine modification in pathologic angiogenesis	55
Hesperidin attenuates hepatic lipid accumulation in mice fed high-fat diet and oleic acid induced HepG2 via AMPK activation	55
Mebendazole; from an anti-parasitic drug to a promising candidate for drug repurposing in colorectal cancer	55
Evidence-based hormonal, mutational, and endocrine-disrupting chemical-induced zebrafish as an alternative model to study PCOS condition similar to mammalian PCOS model	55
Suppression of PCSK9/NF-kB-dependent pathways by acetate ameliorates cardiac inflammation in a rat model of polycystic ovarian syndrome	54
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury	53
Myeloid derived suppressor cells and innate immune system interaction in tumor microenvironment	52
Ergosterol promotes neurite outgrowth, inhibits amyloid-beta synthesis, and extends longevity: In vitro neuroblastoma and in vivo Caenorhabditis elegans evidence	52
PEG-4000 formed polymeric nanoparticles loaded with cetuximab downregulate p21 & stathmin-1 gene expression in cancer cell lines	51
Downregulation of CDC42 contributes to pulmonary vascular endothelial hyperpermeability and acute lung injury induced by seawater drowning	51
Augmented nephroprotective effect of liraglutide and rabeprazole via inhibition of OCT2 transporter in cisplatin-induced nephrotoxicity in rats	51
Spontaneous and familial models of Alzheimer's disease: Challenges and advances in preclinical research	50
Upregulation of miR-222-3p alleviates the symptom of aortic dissection through targeting STAT3	50
Protective role of ellagic acid and taurine against fluoxetine induced hepatotoxic effects on biochemical and oxidative stress parameters, histopathological changes, and gene expressions of IL-1β, NF-	50
Copper homeostasis and cuproptosis in mitochondria	50
Pancreastatin inhibitor PSTi8 prevents free fatty acid-induced oxidative stress and insulin resistance by modulating JNK pathway: In vitro and in vivo findings	49
CpG-mediated TLR9 signaling pathway enhances the efficacy of the OprF/PcrV DNA vaccine with cGAS-STING-activating properties	49

Regulation of metabolism by circadian rhythms: Support from time-restricted eating, intestinal microbiota & omics analysis	49
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway	49
The chromatin remodeling protein BRG1 mediates Ang II induced pro-fibrogenic response in renal fibroblasts	49
Exploring Lin28 proteins: Unravelling structure and functions with emphasis on nervous system malignancies	48
Fluid shear stress facilitates prostate cancer metastasis through Piezo1-Src-YAP axis	48
Retraction notice to “miR-98-5p inhibits gastric cancer cell stemness and chemoresistance by targeting branched-chain aminotransferases 1” [Life Sci. 276 (2021) 119405]	48
Modulation of cardiac voltage-activated K+ currents by glypican 1 heparan sulfate proteoglycan	47
Maladaptive plasticity induced by morphine is mediated by hippocampal astrocytic Connexin-43	47
Ser235 phosphorylation of hepatitis C virus NS5A is required for NS5A dimerization and drug resistance	47
Cancer cell's internal and external warriors: Autophagosomes and exosomes	47
Selective APC-targeting of a novel Fc-fusion multi-immunodominant recombinant protein (tTax-tEnv:mFcγ2a) for HTLV-1 vaccine development	47
Editorial Board	46
Corrigendum to “Deferiprone and efonidipine mitigated iron-overload induced neurotoxicity in wild-type and thalassemic mice” [Life Sci. 239 (2019) 116878]	46
AP-2α decreases TMZ resistance of recurrent GBM by downregulating MGMT expression and improving DNA damage	45
Editorial Board	45
Retraction notice to “Sevoflurane improves nerve regeneration and repair of neurological deficit in brain damage rats via microRNA-490-5p/CDK1 axis” [Life Sci. 271 (2021) 119111]	45
Pentadecapeptide BPC 157 efficiently reduces radiation-induced liver injury and lipid accumulation through Kruppel-like factor 4 upregulation both in vivo and in vitro	44
Comprehensive insights into the multifaceted roles of the transient receptor potential vanilloid 1 channel in the digestive system	44
Activation of CB1R alleviates autism spectrum disorder-like behavior and synaptic impairments	43
Nanocellulose dysregulated glucose homeostasis in female mice on a Western diet: The role of gut microbiome	43
Liraglutide attenuates doxorubicin-induced cardiomyocyte ferroptosis via DHHC7-mediated STAT3 palmitoylation	43
Anti-apoptotic and neurogenic properties in the hippocampus as possible mechanisms for learning and memory improving impacts of vitamin D in hypothyroid rats during the growth period	43
Understanding the physiological mechanisms and therapeutic targets of diseases: Lipidomics strategies	43
Supression Thioredoxin reductase 3 exacerbates the progression of liver cirrhosis via activation of ferroptosis pathway	42
Aerobic exercise training attenuates ischemia-reperfusion injury in mice by decreasing the methylation level of METTL3-associated m6A RNA in cardiomyocytes	42
Pathophysiologic effects of waterpipe (shisha) smoke inhalation on liver morphology and function in mice	41
Nerolidol attenuates dehydroepiandrosterone-induced polycystic ovary syndrome in rats by regulating oxidative stress and decreasing apoptosis	41
A new view on functions of the lysine demalonylase activity of SIRT5	41
Exploring the therapeutic potential of tetrahydrobiopterin for heart failure with preserved ejection fraction: A path forward	40
Catechins prevent obesity-induced kidney damage by modulating PPARγ/CD36 pathway and gut-kidney axis in rats	40
Interrogating Salmonella Typhi biofilm formation and dynamics to understand antimicrobial resistance	40
Therapeutic applications of mesenchymal/medicinal stem/signaling cells preconditioned with external factors: Are there more efficient approaches to utilize their regenerative potential?	40
Geniposide improves depression-like behavior in prenatal stress male offspring through restoring HPA axis- and glucocorticoid receptor-associated dysfunction	40
Glucocorticoid reduces mortality in LPS-induced sepsis mouse model by inhibiting JAK1/STAT3-mediated inflammatory response and restoring tricarboxylic acid cycle	39
Transcriptional and post-translational mechanisms of ECM remodeling in rotator cuff tendons under hyperlipidemic conditions	39
Contributions of the gut microbiota to Gulf War Illness susceptibility: Findings from a mouse model	39
Gastric dilation following vertical sleeve gastrectomy reflects adaptive stem cell-driven regeneration without association with weight regain or increased cancer risk	39
Altered sperm fate in the reproductive tract milieu due to oxidative stress leads to sub-fertility in type 1 diabetes females: A Drosophila-based study	39
The hepatoprotective effects of n3-polyunsaturated fatty acids against non-alcoholic fatty liver disease in diabetic rats through the FOXO1/PPARα/GABARAPL1 signalling pathway	39
The role of RAB12 in inhibiting osteogenic differentiation and driving metabolic dysregulation in osteoporosis	39
8-Geranyloxycarbostyril as a potent 15-LOX-1 inhibitor showed great anti-tumor effects against prostate cancer	39
Altered GnRH neuron-glia networks close to interface of polycystic ovary syndrome: Molecular mechanism and clinical perspectives	38
Effects of apelin on age-associated neovascularization impairment in peripheral artery disease	38
Modulating intestinal viruses: A potential avenue for improving metabolic diseases with unresolved challenges	38
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae	38
CD44s and CD44v8-10 isoforms confer acquired resistance to osimertinib by activating the ErbB3/STAT3 signaling pathway	38
Corrigendum to “Exercise improves cardiac function and attenuates myocardial inflammation and apoptosis by regulating APJ/STAT3 in mice with stroke” [Life Sci. 332 (2023) 122041]	38
Depot- and diabetes-specific differences in norepinephrine-mediated adipose tissue angiogenesis, vascular tone, collagen deposition and morphology in obesity	38
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models	38
Oxidative and endoplasmic reticulum stress develop adverse metabolic effects due to the high-fat high-fructose diet consumption from birth to young adulthood	37
Biliverdin alleviates cerebral ischemia-reperfusion injury by inhibiting autophagy via the lncRNA TUG1 /miR-204-5p/P4HB axis	37
PXDNL activates the motility of urothelial bladder carcinoma cells through the Wnt/β-catenin pathway and has a prognostic value	37
PPARγ agonist alleviates sepsis-related liver injury by modulating M1/M2 macrophage polarization via the PPARγ/IκBα/NF-κB pathway	37
Tumor-associated macrophages: Potential target of natural compounds for management of breast cancer	37
Oxidative stress in animal models of obesity caused by hypercaloric diets: A systematic review	37
Moderate intestinal immunopathology after acute oral infection with Toxoplasma gondii oocysts is associated with expressive levels of serotonin	37
The potential protective effects of estradiol and 2-methoxyestradiol in ischemia reperfusion-induced kidney injury in ovariectomized female rats	37
Noxious ramifications of cosmetic pollutants on gastrointestinal microbiome: A pathway to neurological disorders	36
Gut microbiota and late-life depression: from mechanistic insights to clinical rehabilitation	36
The IRβ/HCF-1/ChREBP axis: A new paradigm in insulin-regulated hepatic lipogenesis	36
Tauroursodeoxycholate prevents estradiol 17β-d-glucuronide-induced cholestasis and endocytosis of canalicular transporters by switching off pro-cholestatic signaling pathways	36
Fecal microbiota transplantation for diseases: Therapeutic potential, methodology, risk management in clinical practice	36
An improved mouse model of sepsis based on intraperitoneal injections of the enriched culture of cecum slurry	36
Corrigendum to “Hydroxyl containing benzo[b]thiophene analogs mitigates the acrylamide induced oxidative stress in the zebrafish larvae by stabilizing the glutathione redox cycle” [Life Sci. 298 (2022	35
Simvastatin reduces plasma membrane caveolae and caveolin-1 in uterine leiomyomas	35
Autophagy regulation in ovarian cancer chemoresistance: Molecular mechanisms and emerging frontiers	35
Probenecid induces the recovery of renal ischemia/reperfusion injury via the blockade of Pannexin 1/P2X7 receptor axis	35
Oral fluoxetine treatment changes serotonergic sympatho-regulation in experimental type 1 diabetes	35
Role of sulforaphane in endoplasmic reticulum homeostasis through regulation of the antioxidant response	35
The Rab GTPase in the heart: Pivotal roles in development and disease	35
Cisplatin transported by COX17 induces cochlear damage by binding Myosin IIA to regulate cell pyroptosis induced by mitochondrial dysfunction	35
Oxidative stress imposed in vivo anticancer therapeutic efficacy of novel imidazole-based oxidovanadium (IV) complex in solid tumor	35
Efficacy of lipid nanoparticles-based vaccine to protect against vulvovaginal candidiasis (VVC): Implications for women's reproductive health	35
5/6 nephrectomy affects enteric glial cells and promotes impaired antioxidant defense in the colonic neuromuscular layer	35
Unveiling OSCP as the potential therapeutic target for mitochondrial dysfunction-related diseases	35
New role of obscure acylation modifications in cardiovascular diseases: what's beyond?	35
Low dose Taxol ameliorated renal fibrosis in mice with diabetic kidney disease by downregulation of HIPK2	35
IKKβ inhibits cognitive memory and adult hippocampal neurogenesis by modulating the β-catenin pathway	34
The role of viruses in cancer progression versus cancer treatment: A dual paradigm	34
Update on the transdifferentiation of pancreatic cells into functional beta cells for treating diabetes	34

The potential of sertoli cells (SCs) derived exosomes and its therapeutic efficacy in male reproductive disorders	34
Mollugin activates GLP-1R to improve cognitive dysfunction in type 2 diabetic mice	34
Pain in rheumatoid arthritis: Emerging role of high mobility group box 1 protein-HMGB1	34
CAMSAP2 enhances lung cancer cell metastasis by mediating RASAL2 degradation	33
Exploring the gut-lung-brain axis: Focus on endothelial dysfunction, impaired bioenergetics, and strategies to mitigate lung and cognitive disorders	33
Imatinib mitigates experimentally-induced ulcerative colitis: Possible contribution of NF-kB/JAK2/STAT3/COX2 signaling pathway	33
Renal cell carcinoma management: A step to nano-chemoprevention	33
Phloretin as an add-on therapy to losartan attenuates diabetes-induced AKI in rats: A potential therapeutic approach targeting TLR4-induced inflammation	33
The physical exercise-induced oxidative/inflammatory response in peripheral blood mononuclear cells: Signaling cellular energetic stress situations	33
Ursodeoxycholic acid alleviates atopic dermatitis-associated inflammatory responses in HaCaT and RBL-2H3 cells and DNCB/DFE-treated mice	33
Quercetin mitigates memory deficits in scopolamine mice model via protection against neuroinflammation and neurodegeneration	33
Targeting calcium homeostasis and impaired inter-organelle crosstalk as a potential therapeutic approach in Parkinson's disease	33
Covid-19 a triggering factor of autoimmune and multi-inflammatory diseases	33
The influence of microenvironment stiffness on endothelial cell fate: Implication for occurrence and progression of atherosclerosis	33
Exosomal-long non-coding RNAs journey in colorectal cancer: Evil and goodness faces of key players	32
Circ_0002638 drives squamous cell lung cancer (LUSC) progression and chemotherapy resistance by inhibiting ferroptosis via SENP1-mediated deSUMOylation of ACSL4	32
Comparative transcriptome and Lipidome analyses suggest a lipid droplet-specific response to heat exposure of brown adipose tissue in normal and obese mice	32
Mesenchymal stem cell-derived exosomes: Characteristics and applications in disease pathology and management	32
Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia	32
Nesfatin-1 ameliorates oxidative brain damage and memory impairment in rats induced with a single acute epileptic seizure	32
Study of immunomodulatory effects of mesenchymal stem cell-derived exosomes in a mouse model of LPS induced systemic inflammation	32
Editorial Board	32
H-ras-targeted genetic therapy remarkably surpassed docetaxel treatment in inhibiting chemically induced hepatic tumors in rats	32
N-acetylcysteine alleviates oxidative stress and apoptosis and prevents skeletal muscle atrophy in type 1 diabetes mellitus through the NRF2/HO-1 pathway	32
Refined immunoRNases for the efficient targeting and selective killing of tumour cells: A novel strategy	31
Editorial Board	31
Heterodimerization of apelin and opioid receptor-like 1 receptors mediates apelin-13-induced G protein biased signaling	31
Regucalcin downregulation in human cancer	31
FAM96A suppresses epithelial–mesenchymal transition and tumor metastasis by inhibiting TGFβ1 signals	31
Editorial Board	31
ZD-2, a novel DPP4 inhibitor, protects islet β-cell and improves glycemic control in high-fat-diet-induced obese mice	31
Subacute administration of cilostazol modulates PLC-γ/PKC-α/p38/NF-kB pathway and plays vascular protective effects through eNOS activation in early stages of atherosclerosis development	31
Secretoglobin 3A2 peptides have therapeutic potential for allergic airway inflammation	31
The role of organic anion transport peptides in cyclophosphamide-induced hepatotoxicity in high-fat diet mice	31
Research progress on pathogenesis and treatment of febrile seizures	31
Sugar-sweetened beverage consumption retarded weight gain but not induced depression and anxiety-like behaviors in mice	31
Activation of megakaryocytic leukemia 1 in endothelial cells contributes to diabetic retinopathy in mice	31
Probiotics and the reduction of SARS-CoV-2 infection through regulation of host cell calcium dynamics	31
Corrigendum to “Protective effects of Nrf2 against sepsis-induced hepatic injury” [Life Sci. 282 (2021) 119807]	30
Organic vs. inorganic nitrates: Metabolic and vascular outcomes in STZ-induced diabetes in mice	30
Alpha-lipoic acid protects against aortic aneurysm and dissection by improving vascular smooth muscle cell function	30
FoxM1 promotes the proliferation of cervical adenocarcinoma cells through transcriptional activation of FAM83D	30
Corrigendum to “NEAT1: Culprit lncRNA linking PIG C, MSLN, and CD80 in triple-negative breast cancer” [Life Sci., volume 299 (2022) 120523]	30
Chitosan based nanoformulation expressing miR-155 as a promising adjuvant to enhance Th1-biased immune responses	30
Hyperoxic exposure alters intracellular bioenergetics distribution in human pulmonary cells	30
Chronic alcohol feeding alters lymph and plasma proteome in a rodent model	30
Editorial Board	30
Corrigendum to “In vivo biochemical evaluations of some β-lactam group antibiotics on glutathione reductase and glutathione S-transferase enzyme activities” [Life Sci., volume 231 (2019) 116572]	30
Gastrointestinal manifestations of long COVID	30
Thyroid hormone ameliorates ursodeoxycholic acid-induced heart damage in zebrafish embryos	30
Cryopreserved clinical-grade human embryonic stem cell-derived dopaminergic progenitors function in Parkinson's disease models	29
Genome-wide screening and identification of potential kinases involved in endoplasmic reticulum stress responses	29
Neuronal PAC1 deletion impairs structural plasticity	29
S1PR2/Wnt3a/RhoA/ROCK1/β-catenin signaling pathway promotes diabetic nephropathy by inducting endothelial mesenchymal transition and impairing endothelial barrier function	29
N-phenethyl-5-phenylpicolinamide alleviates inflammation in acute lung injury by inhibiting HIF-1α/glycolysis/ASIC1a pathway	29
Antibiotic-induced microbiome depletion remodels daily metabolic cycles in the brain	29
The association between type 1 diabetes and exercise/physical activity and prolongation of the honeymoon phase in patients	29
Identification of distinct immune infiltration and potential biomarkers in patients with liver ischemia-reperfusion injury	29
Untargeted metabolomics profiling of 24-h ultramarathon runners: new insights into the biochemical alterations and the identification of performance biomarkers	29
A direct estrogenic involvement in the expression of human hypocretin	29
Synovial microenvironment in temporomandibular joint osteoarthritis: crosstalk with chondrocytes and potential therapeutic targets	29
MicroRNA-217 modulates pancreatic cancer progression via targeting ATAD2	29
Protective effects of low-temperature plasma on cisplatin-induced nephrotoxicity	29
Maternal obesity impacts fetal liver androgen signalling in a sex-specific manner	29
Uterine-derived exosomes induce the M2 polarization of macrophages via miR-210-3p/ATP5D to promote endometriosis progression	29
Inhibition of the FOXO1–ROCK1 axis mitigates cardiomyocyte injury under chronic hypoxia in Tetralogy of Fallot by maintaining mitochondrial quality control	29
Rodent models for dry eye syndrome: Standardization using benzalkonium chloride and scopolamine hydrobromide	28
Mesenchymal stem cell-based therapy as a new therapeutic approach for acute inflammation	28
Potential therapeutic and diagnostic approaches of exosomes in multiple sclerosis pathophysiology	28
Omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity, BDNF and amyloid-B in rat hippoca	28
Enhanced eNOS/nitric oxide production by nebivolol interferes with TGF-β1/Smad3 signaling and collagen I deposition in the kidney after prolonged tacrolimus administration	28
Auto- and paracrine rewiring of NIX-mediated mitophagy by insulin-like growth factor-binding protein 7 in septic AKI escalates inflammation-coupling tubular damage	28
Antineoplastic agents in chemotherapy facilitating tumor growth and angiogenesis in the interval administrations	28
Distinct roles for orexin-1 and orexin-2 receptors in the dentate gyrus of the hippocampus in the methamphetamine-seeking behavior in the rats	28
Exosomal miR-1228-5p down-regulates DUSP22 to promotes cell proliferation and migration in small cell lung cancer	28
Vulnerability and resilience to cardiovascular and neuroendocrine effects of stress in adult rats with historical of chronic stress during adolescence	28
Gut microbiota in obesity and related complications: Unveiling the complex interplay	28
Lunasin ameliorates glucose utilization in C2C12 myotubes and metabolites profile in diet-induced obese mice benefiting metabolic disorders	28
Semaglutide alleviates the pancreatic β cell function via the METTL14 signaling and modulating gut microbiota in type 2 diabetes mellitus mice	28
Levistolide A ameliorates fibrosis in chronic kidney disease via modulating multitarget actions in vitro and in vivo	28
Dysregulation of immune and metabolism pathways in maternal immune activation induces an increased risk of autism spectrum disorders	28
Role of melatonin in mitigation of insulin resistance and ensuing diabetic cardiomyopathy	27
New insights on the impact of gut microbiota on premenstrual disorders. Will probiotics solve this mystery?	27
MicroRNA-23b prevents aortic aneurysm formation by inhibiting smooth muscle cell phenotypic switching via FoxO4 suppression	27
The effect of mesenchymal stem cell-derived supernatant nasal administration on lung inflammation and immune response in BCG-vaccinated BALB/c mice	27
The underlying mechanism and therapeutic potential of IFNs in viral-associated cancers	27
The prevalence of drug–drug interactions in cancer therapy and the clinical outcomes	27
Cigarette smoke-induced galectin-3 as a diagnostic biomarker and therapeutic target in lung tissue remodeling	27
Fgf21-Dubosiella axis mediates the protective effects of exercise against NAFLD development	27
Targeting DNA methylation in diabetic kidney disease: A new perspective	27
Challenges in clinical practice, biological mechanism and prospects of physical ablation therapy for COPD	27
DLGAP5 upregulates E2F1 to promote prostate adenocarcinoma neuroendocrine differentiation	27
RNF8-mediated multi-ubiquitination of MCM7: Linking disassembly of the CMG helicase with DNA damage response in human cells	27
Genetics, epigenetics and autoimmunity constitute a Bermuda triangle for the pathogenesis of rheumatoid arthritis	27
Role of caspase-8 and/or -9 as biomarkers that can distinguish the potential to cause toxic- and immune related-adverse event, for the progress of acetaminophen-induced liver injury	27