Nature

Article	Citations
Highly accurate protein structure prediction with AlphaFold	18635
Array programming with NumPy	10378
The mutational constraint spectrum quantified from variation in 141,456 humans	5963
Factors associated with COVID-19-related death using OpenSAFELY	4462
Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe	2388
Pseudo-halide anion engineering for α-FAPbI3 perovskite solar cells	2167
Perovskite solar cells with atomically coherent interlayers on SnO2 electrodes	2160
Efficient perovskite solar cells via improved carrier management	2031
Highly accurate protein structure prediction for the human proteome	1787
Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7	1693
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls	1669
Longitudinal analyses reveal immunological misfiring in severe COVID-19	1639
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody	1638
Convergent antibody responses to SARS-CoV-2 in convalescent individuals	1636
SARS-CoV-2 vaccines in development	1613
Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization	1558
COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses	1463
Detection of a SARS-CoV-2 variant of concern in South Africa	1357
SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies	1310
Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike	1289
Evolution of antibody immunity to SARS-CoV-2	1288
Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies	1281
Expanded encyclopaedias of DNA elements in the human and mouse genomes	1277
Photocatalytic water splitting with a quantum efficiency of almost unity	1264
Spike mutation D614G alters SARS-CoV-2 fitness	1238

Human neutralizing antibodies elicited by SARS-CoV-2 infection	1237
A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2	1179
Design of robust superhydrophobic surfaces	1172
Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa	1156
Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults	1146
Pathogenesis and transmission of SARS-CoV-2 in golden hamsters	1144
Towards complete and error-free genome assemblies of all vertebrate species	1143
Considerable escape of SARS-CoV-2 Omicron to antibody neutralization	1109
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants	1101
Designing the next generation of proton-exchange membrane fuel cells	1094
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness	1093
Effects of extracellular matrix viscoelasticity on cellular behaviour	1075
SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19	1024
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program	1024
The effect of large-scale anti-contagion policies on the COVID-19 pandemic	1012
Mapping genomic loci implicates genes and synaptic biology in schizophrenia	1010
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion	975
Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2	972
The changing landscape of atherosclerosis	965
Correlates of protection against SARS-CoV-2 in rhesus macaques	960
Genetic mechanisms of critical illness in COVID-19	946
Mobility network models of COVID-19 explain inequities and inform reopening	946
Sex differences in immune responses that underlie COVID-19 disease outcomes	943
A molecular cell atlas of the human lung from single-cell RNA sequencing	939
High-dimensional characterization of post-acute sequelae of COVID-19	935
Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England	928
Potently neutralizing and protective human antibodies against SARS-CoV-2	925
The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice	907
A 20-year retrospective review of global aquaculture	907
Structures and distributions of SARS-CoV-2 spike proteins on intact virions	883
Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization	881
Reproducible brain-wide association studies require thousands of individuals	869
BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection	865
Cells of the adult human heart	846
A comprehensive quantification of global nitrous oxide sources and sinks	837
Accelerated discovery of CO2 electrocatalysts using active machine learning	832
Age-specific mortality and immunity patterns of SARS-CoV-2	824
Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift	823
Effect of non-pharmaceutical interventions to contain COVID-19 in China	819
Proteomics of SARS-CoV-2-infected host cells reveals therapy targets	804
SARS-CoV-2 is associated with changes in brain structure in UK Biobank	801
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer	782
Fibrosis: from mechanisms to medicines	780
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity	776
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity	762
Photocatalytic solar hydrogen production from water on a 100-m2 scale	760
SARS-CoV-2 evolution during treatment of chronic infection	757
Developing fibrillated cellulose as a sustainable technological material	748
Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’	741
Parallel convolutional processing using an integrated photonic tensor core	741

FinnGen provides genetic insights from a well-phenotyped isolated population	732
Controlled growth of perovskite layers with volatile alkylammonium chlorides	721
Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7	717
Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques	706
Short-range order and its impact on the CrCoNi medium-entropy alloy	705
ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques	705
Viral and host factors related to the clinical outcome of COVID-19	690
Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion	687
Animal models for COVID-19	685
A large-scale binding and functional map of human RNA-binding proteins	666
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse	665
Strong tough hydrogels via the synergy of freeze-casting and salting out	665
A mobile robotic chemist	653
How China could be carbon neutral by mid-century	649
NASH limits anti-tumour surveillance in immunotherapy-treated HCC	642
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing	633
ChatGPT: five priorities for research	624
Antibody evasion properties of SARS-CoV-2 Omicron sublineages	622
Programmable photonic circuits	617
A structural variation reference for medical and population genetics	612
Exploring tissue architecture using spatial transcriptomics	610
A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity	609
Pattern-recognition receptors are required for NLR-mediated plant immunity	604
Ultralow contact resistance between semimetal and monolayer semiconductors	601
Accelerated global glacier mass loss in the early twenty-first century	600
Structure of replicating SARS-CoV-2 polymerase	600
High and rising economic costs of biological invasions worldwide	589
Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection	587
Variability in the analysis of a single neuroimaging dataset by many teams	586
Mapping the human genetic architecture of COVID-19	585
SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo	580
Promises and prospects of two-dimensional transistors	577
Single-particle cryo-EM at atomic resolution	577
Self-powered soft robot in the Mariana Trench	577
Large-area display textiles integrated with functional systems	576
Filling metal–organic framework mesopores with TiO2 for CO2 photoreduction	574
SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses	573
All-perovskite tandem solar cells with improved grain surface passivation	570
Brain charts for the human lifespan	564
Mastering Atari, Go, chess and shogi by planning with a learned model	563
BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans	562
Respiratory disease in rhesus macaques inoculated with SARS-CoV-2	556
11 TOPS photonic convolutional accelerator for optical neural networks	555
Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies	554
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia	550
Mutual potentiation of plant immunity by cell-surface and intracellular receptors	550
Diverse functional autoantibodies in patients with COVID-19	548
Infection of dogs with SARS-CoV-2	544
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis	541
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets	532
Negative feedback control of neuronal activity by microglia	532
Isolation of SARS-CoV-2-related coronavirus from Malayan pangolins	531
Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2	529
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma	528
Multiple wheat genomes reveal global variation in modern breeding	527
Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin	526
Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5	522
Telomere-to-telomere assembly of a complete human X chromosome	513
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia	509
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid	509
A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures	508
Cell-programmed nutrient partitioning in the tumour microenvironment	501
DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25	500
Lysosome-targeting chimaeras for degradation of extracellular proteins	499
Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2	499
Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma	498
Senolytic CAR T cells reverse senescence-associated pathologies	497
Lymph protects metastasizing melanoma cells from ferroptosis	496
Ligand-engineered bandgap stability in mixed-halide perovskite LEDs	494
BNT162b vaccines protect rhesus macaques from SARS-CoV-2	493
Global priority areas for ecosystem restoration	484
Cross-tissue organization of the fibroblast lineage	483
Surface reaction for efficient and stable inverted perovskite solar cells	482
RETRACTED ARTICLE: Room-temperature superconductivity in a carbonaceous sulfur hydride	480
Quantum phases of matter on a 256-atom programmable quantum simulator	477
Zoonotic host diversity increases in human-dominated ecosystems	466
Co-designing electronics with microfluidics for more sustainable cooling	463
Atomic-resolution protein structure determination by cryo-EM	463
Leading hadronic contribution to the muon magnetic moment from lattice QCD	463
Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant	462

Area-based conservation in the twenty-first century	461
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters	459
Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron	455
Tunable strongly coupled superconductivity in magic-angle twisted trilayer graphene	453
Structures of α-synuclein filaments from multiple system atrophy	449
The coding capacity of SARS-CoV-2	442
Critical advances and future opportunities in upcycling commodity polymers	440
An integrated space-to-ground quantum communication network over 4,600 kilometres	436
Key role of chemistry versus bias in electrocatalytic oxygen evolution	436
Tunable correlated states and spin-polarized phases in twisted bilayer–bilayer graphene	435
Inference in artificial intelligence with deep optics and photonics	434
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV	434
Structure-based classification of tauopathies	432
Reprogramming to recover youthful epigenetic information and restore vision	431
T cell responses to SARS-CoV-2 spike cross-recognize Omicron	431
Unextractable fossil fuels in a 1.5 °C world	429
Plasticity of ether lipids promotes ferroptosis susceptibility and evasion	429
Machine learning-aided engineering of hydrolases for PET depolymerization	428
Composition-dependent thermodynamics of intracellular phase separation	426
Satellite imaging reveals increased proportion of population exposed to floods	425
A bright millisecond-duration radio burst from a Galactic magnetar	424
High-performance brain-to-text communication via handwriting	424
A fast radio burst associated with a Galactic magnetar	421
Topological polaritons and photonic magic angles in twisted α-MoO3 bilayers	420
In situ Raman spectroscopy reveals the structure and dissociation of interfacial water	417
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates	417
SARS-CoV-2 spike D614G change enhances replication and transmission	415
Homeostatic mini-intestines through scaffold-guided organoid morphogenesis	413
A molecular single-cell lung atlas of lethal COVID-19	412
Bending the curve of terrestrial biodiversity needs an integrated strategy	411
A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing	410
The major genetic risk factor for severe COVID-19 is inherited from Neanderthals	409
Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation	408
Heavily mutated Omicron variant puts scientists on alert	405
Decade-long leukaemia remissions with persistence of CD4+ CAR T cells	403
A biomimetic eye with a hemispherical perovskite nanowire array retina	402
The online competition between pro- and anti-vaccination views	401
SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans	401
The future of food from the sea	399
High-resolution X-ray luminescence extension imaging	399
A dynamic stability design strategy for lithium metal solid state batteries	397
A perspective on potential antibody-dependent enhancement of SARS-CoV-2	397
Exome sequencing and analysis of 454,787 UK Biobank participants	393
Efficient and stable blue quantum dot light-emitting diode	393
Tunable spin-polarized correlated states in twisted double bilayer graphene	391
Swarm Learning for decentralized and confidential clinical machine learning	391
Stable room-temperature continuous-wave lasing in quasi-2D perovskite films	390
Decoding myofibroblast origins in human kidney fibrosis	390
Dysregulation of brain and choroid plexus cell types in severe COVID-19	389
Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis	380
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids	379
Climate change increases cross-species viral transmission risk	379
Inherited causes of clonal haematopoiesis in 97,691 whole genomes	379
Shifting attention to accuracy can reduce misinformation online	375
Distribution control enables efficient reduced-dimensional perovskite LEDs	375
Bayesian reaction optimization as a tool for chemical synthesis	374
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice	373
Amazonia as a carbon source linked to deforestation and climate change	372
An aged immune system drives senescence and ageing of solid organs	370
Comparative cellular analysis of motor cortex in human, marmoset and mouse	370
Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron	367
Half a century of global decline in oceanic sharks and rays	366
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape	365
The power of genetic diversity in genome-wide association studies of lipids	364
Closed-loop recycling of polyethylene-like materials	364
Sources of particulate-matter air pollution and its oxidative potential in Europe	361
Entanglement-based secure quantum cryptography over 1,120 kilometres	360
NINJ1 mediates plasma membrane rupture during lytic cell death	359
Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM	358
The central role of DNA damage in the ageing process	356
Exome sequencing and characterization of 49,960 individuals in the UK Biobank	356
Direct observation of chemical short-range order in a medium-entropy alloy	354
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas	353
The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer	353
Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2	351
Global human-made mass exceeds all living biomass	350
Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform	350
ChatGPT listed as author on research papers: many scientists disapprove	349
Thermal-expansion offset for high-performance fuel cell cathodes	349
Skilful precipitation nowcasting using deep generative models of radar	345
Correlative operando microscopy of oxygen evolution electrocatalysts	344
Reconstruction of the full transmission dynamics of COVID-19 in Wuhan	344
Evidence for 28 genetic disorders discovered by combining healthcare and research data	343
‘It will change everything’: DeepMind’s AI makes gigantic leap in solving protein structures	341
A prion-like domain in ELF3 functions as a thermosensor in Arabidopsis	341
A census of baryons in the Universe from localized fast radio bursts	341
Rare coding variants in ten genes confer substantial risk for schizophrenia	341
SARS-CoV-2 infection and persistence in the human body and brain at autopsy	340
Additive manufacturing of silica aerogels	338
A disordered rock salt anode for fast-charging lithium-ion batteries	337
Protecting the global ocean for biodiversity, food and climate	336
Solar-to-hydrogen efficiency of more than 9% in photocatalytic water splitting	335
Massively parallel coherent laser ranging using a soliton microcomb	334
Genome-wide enhancer maps link risk variants to disease genes	334
Large Chinese land carbon sink estimated from atmospheric carbon dioxide data	331