OOIR: Observatory of International Research

Papers

(The H4-Index of New England Journal of Medicine is 246. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)

Article	Citations
How Can We Fully Realize SNAP’s Health Benefits?	3216
Gastric Emptying Abnormalities in Diabetes Mellitus	2976
Childhood Risk Factors and Adult Cardiovascular Events	2484
Gantenerumab in Early Alzheimer’s Disease	2399
Measurable Residual Disease–Guided Therapy for Chronic Lymphocytic Leukemia	1957
Striking a Balance — Advancing Physician Collective-Bargaining Rights and Patient Protections	1877
Nutritional Support for Moderate-to-Late–Preterm Infants — A Randomized Trial	1859
Race in Medicine — Genetic Variation, Social Categories, and Paths to Health Equity	1706
Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk	1690
Implanted System for Orthostatic Hypotension in Multiple-System Atrophy	1684
Receipt of mRNA Vaccine against Covid-19 and Myocarditis	1656
Malnutrition in Adults	1595
Mepolizumab to Prevent Exacerbations of COPD with an Eosinophilic Phenotype	1548
Kidney Injury and Hair-Straightening Products Containing Glyoxylic Acid	1501
A Trial of Trimethoprim–Sulfamethoxazole in Pregnancy to Improve Birth Outcomes	1434
Debating Race and the Diagnosis of Anemia — How Medicine Moved Away from Race-Based Standards	1288
Investigating Injustices in the Journal ’s History, Part 2	1283
Tenecteplase for Stroke — Opening the Window?	1243
Hemotympanum with a Basilar Skull Fracture	1225
Secondary Hypertrophic Osteoarthropathy	1194
Intravenous Levothyroxine for Unstable Brain-Dead Heart Donors	1166
Psychosocial Functioning in Transgender Youth after 2 Years of Hormones	1156
Testing for Arginine Vasopressin Deficiency	1081
U.S. Law and Discrimination in Health Care	1042
Case 40-2022: A 38-Year-Old Man with Exertional Chest Discomfort	1037

The Muffin Question	1036
Hiding in Plain Sight	995
Bilothorax	934
Audio Interview: Assessing Bivalent Vaccines against Covid-19	913
A Modern Therapy for an Ancient Disease	909
Overcoming Resistance — Omission of Radiotherapy for Low-Risk Breast Cancer	878
From the Eyeball Test to the Algorithm — Quality of Life, Disability Status, and Clinical Decision Making in Surgery	856
Monoclonal Antibodies for Malaria	832
Designing Cures 2.0 — From Corridors to Cornerstones	826
Nonketotic Hyperglycemic Hemichorea	822
Automatic Insurance Policies — Important Tools for Preventing Coverage Loss	784
Gingival Infiltration in Acute Monocytic Leukemia	782
Hyperpigmentation in Vitamin B ₁₂ Deficiency	780
Use of Polygenic Scores to Select Embryos	779
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors for Anemia in CKD	770
Alteplase and Thrombectomy — Not a Bridge to Dismantle	762
Primaquine and Plasmodium vivax Malaria Recurrence in Brazil	753
Ruxolitinib for Chronic Graft-versus-Host Disease	733
STEP 1 for Effective Weight Control — Another First Step?	728
The Importance of Context in Covid-19 Vaccine Safety	725
Breaking the Sacred Promise	718
Ménétrier’s Disease	701
Rethinking Shadowing for Aspiring Physicians	684
Nationwide, Couple-Based Genetic Carrier Screening	681
Poet as Patient	671
Navigating and Communicating about Serious Illness and End of Life	653
Preparing for the Next Pandemic — Expanding and Coordinating Global Regulatory Capacity	653
Liver Transplantation for Mahvash Disease, an Inborn Error of Metabolism	647
Adrenal Involvement in Disseminated Histoplasmosis	635
Optical Coherence Tomography and Eye Care	629
Multicentric Reticulohistiocytosis	629
Zilebesiran for Hypertension	627
Long-Term Outcomes of Resynchronization–Defibrillation for Heart Failure	626
Black Dot Tinea Capitis	620
Screening for Prostate Cancer	616
Timing Is Everything — Evidence for When to Perform Complete Revascularization in STEMI	599
Ten Years of Incidental, Secondary, and Actionable Findings	598
Convalescent Rash of Dengue	595
Modifiable Risk Factors and Cardiovascular Outcomes	588
Turning CMS into a Health Technology Assessment Organization	588
BCMA-Targeted T-Cell Engager for Autoimmune Hemolytic Anemia after CD19 CAR T-Cell Therapy	587
Out of Pocket Getting Out of Hand — Reducing the Financial Toxicity of Rapidly Approved Drugs	586
Middle Meningeal Artery Embolization for Subdural Hematoma	586
Evidence-Based Work Design — Bridging the Divide	576
Perioperative Durvalumab in Bladder Cancer	575
A Swell Diagnosis	575
Effect of a Reduced PCV10 Dose Schedule on Pneumococcal Carriage in Vietnam	573
SENIOR-RITA — Is It All about Angiography?	566
Asciminib in Newly Diagnosed Chronic Myeloid Leukemia	564
Postacute Sequelae of SARS-CoV-2 Infection in Several Eras	561

Targeting CSF1R in Chronic GVHD — Lessons in Translation	555
Race-Based Diagnosis, Part 1 — ITT Episode 33	554
Prolonging Cellular Life after Hypoxic Death	546
Mucosal IgA against SARS-CoV-2 Omicron Infection	545
Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial	543
Bismuth Subsalicylate Poisoning	542
Early Treatment with Sotrovimab for Covid-19	533
Covid-19 Infections in Vaccinated Health Care Workers	530
Foreign-Body Aspiration in a Child	515
Bumps in the Road	515
Virotherapy for Brain Tumors — Defining the Path to Success	512
Catching Up on REMs	509
Audio Interview: Dissecting the Host Response to SARS-CoV-2	501
Maintenance or Discontinuation of Antidepressants in Primary Care	501
Early Active Mobilization during Mechanical Ventilation in the ICU	500
Freedom of Speech	498
Vaccine Breakthrough Infections with SARS-CoV-2 Variants	496
Cholelithiasis, Cholecystitis, and Choledocholithiasis	494
Automated Insulin Pump in Type 2 Diabetes	493
Gazing into a Crystal Ball	493
Case 18-2025: A 63-Year-Old Woman with Dyspnea on Exertion	486
Racial Inequality in Prescription Opioid Receipt — Role of Individual Health Systems	484
Haloperidol for the Treatment of Delirium in ICU Patients	483
Fever of Unknown Origin	483
Paget’s Disease of the Breast	479
Threatening the Future of Global Health — NIH Policy Changes on International Research Collaborations	476
Navigating and Communicating about Serious Illness and End of Life	473
Hypothermia or Machine Perfusion in Kidney Donors	470
Use of Wastewater for Mpox Outbreak Surveillance in California	467
Belantamab Mafodotin, Bortezomib, and Dexamethasone for Multiple Myeloma	466
Lung Transplantation for Covid-19–Related Respiratory Failure in the United States	462
Reteplase versus Alteplase for Acute Ischemic Stroke	462
Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile	454
Striving for Diversity in Research Studies	452
New Horizons in the Treatment of Osteosarcoma	450
Gene Therapy with Fidanacogene Elaparvovec in Adults with Hemophilia B	445
Bronchiectasis — A Clinical Review	441
Empagliflozin in Heart Failure with a Preserved Ejection Fraction	440
Edoxaban versus Vitamin K Antagonist for Atrial Fibrillation after TAVR	437
Periprosthetic Joint Infection	427
First-Line Venetoclax Combinations in Chronic Lymphocytic Leukemia	422
Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts	421
Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction	416
Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer	416
Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer	416
Increasing Firearm-Related Deaths among U.S. Black Rural Youths	415
A Preview of the Dangerous Future of Abortion Bans — Texas Senate Bill 8	414
Targeting Lipoprotein(a) — the Next Frontier in Cardiovascular Disease	413
Covid-19 Surveillance Testing in Nursing Homes	412
Hospital Problems	408
Pegylated Interferon Lambda for Covid-19	407
Trials for Managing Acute Pain — A Clinically Meaningful Small Effect Size?	406
Laryngeal Candidiasis	403
Guilty	402
PD-1 and PD-L1 Blockade plus Chemotherapy in Endometrial Cancer	401
Transfusion Strategy in Myocardial Infarction and Anemia	400
Water-Based and Waterless Surgical Scrub Techniques	399
Case 39-2023: A 43-Year-Old Woman with Chronic Diarrhea, Hair Loss, and Nail and Skin Changes	398
Genetically Modified Porcine-to-Human Cardiac Xenotransplantation	396
Neurovascular Complications of Iatrogenic Fusarium solani Meningitis	396
Audio Interview: The Omicron Variant of SARS-CoV-2	394
Risks and Benefits of Janus Kinase Inhibitors in Rheumatoid Arthritis — Past, Present, and Future	393
Routine Removal of Inferior Vena Cava Filters	390
Focused Cardiac Ultrasonography for Right Ventricular Size and Systolic Function	388
The Increasing Incidence of Early-Onset Colorectal Cancer	386
Case 26-2022: A 48-Year-Old Woman with Cystic Lung Disease	385
Pretomanid in the Treatment of Patients with Tuberculosis in the United States	384
Diagnostic Aspirations	382
Audio Interview: Ending the Covid-19 Public Health Emergency	376
End of a Declared Public Health Emergency — Implications for U.S. Emergency Use Authorizations	373
What’s in a Number? Breaking Down the Residency Match Rate	373
Small Step or Giant Leap? Expanding the Acute Stroke Thrombolysis Window to 24 Hours	371
Genital Herpes Zoster	371
Expect With Me — Group Prenatal Care to Reduce Disparities	368
The Death of an Unlikable Man	368
HIPAA and the Leak of “Deidentified” EHR Data	368
NEJM at AHA — Routine Spironolactone in Acute Myocardial Infarction	366
Intravenous Amino Acids and Kidney Protection	363
Invasive Strategy for Older Patients with MI	363
FINEARTS-HF — The Latest Masterpiece for MRAs in Heart Failure	362

Crinecerfont in Adult Congenital Adrenal Hyperplasia	361
Autoantibodies Targeting Nephrin in Podocytopathies	360
Case 38-2024: A 22-Year-Old Woman with Headache, Fever, and Respiratory Failure	358
Guidance on Energy and Macronutrients across the Life Span	354
Criminalizing Homelessness — The Grants Pass, Oregon, Supreme Court Case	354
Compared with What? Measuring AI against the Health Care We Have	352
Felzartamab in Antibody-Mediated Rejection	346
Academic Freedom in America — In Support of Institutional Voices	345
Postherpetic Abdominal Pseudohernia	345
Making Long-Term Oxygen Therapy Less Burdensome	344
Medication for Gastroesophageal Reflux Disease in Infants	343
Vocal-Cord Polyp Causing Airway Obstruction	342
Chylothorax	341
Broken Both Ways	339
Convalescent Plasma for Covid-19–Induced ARDS	338
Gastric Syphilis	334
A Physician Attack on the FDA — Will the Supreme Court Reduce Access to Mifepristone?	334
Mycoplasma-Induced Rash and Mucositis	333
What We Don’t Know about School Shooter Drills	329
Helicobacter pylori , Homologous-Recombination Genes, and Gastric Cancer	329
Case 21-2023: A 61-Year-Old Man with Eyelid Swelling	328
Public Health’s Role in a Post- Dobbs World — The New York City Abortion Access Hub	327
Audio Interview: Ending the Covid-19 Emergency	327
Moving the Needle on Alzheimer’s Disease with an Anti-Oligomer Antibody	325
Personality Disorders	323
Case 5-2023: A 67-Year-Old Man with Interstitial Lung Disease, Fever, and Myalgias	323
Cholesterol Pericarditis	321
Audio Interview: Rolling Out New Covid-19 Vaccines	321
Atrial Fibrillation — What Is It and How Is It Treated?	320
HIV Prevention and the 340B Drug Pricing Program	318
Booster Doses and Prioritizing Lives Saved	317
Japanese Spotted Fever	317
Benefits and Risks of Iron Interventions in Infants in Bangladesh	316
Treatment of Relapsing HPV Diseases by Restored Function of Natural Killer Cells	313
Vaccine Effectiveness Studies in the Field	312
SGLT2 Inhibitors and False Positive Toxicology Tests	311
Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia	310
The Risks of Normalizing Parental Vaccine Hesitancy	307
In Vitro Efficacy of Antiviral Agents against Omicron Subvariant BA.4.6	306
Tuberculous Meningitis — New Approaches Needed	303
Skeletal Fluorosis	301
Five-Year Outcomes of the Danish Cardiovascular Screening (DANCAVAS) Trial	300
Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity	300
Targeting HER2 -Mutant NSCLC — The Light Is On	300
Prevalence of Mismatch-Repair Deficiency in Rectal Adenocarcinomas	297
“Putting America First” — Undermining Health for Populations at Home and Abroad	295
Treatment of Anal High-Grade Squamous Intraepithelial Lesions to Prevent Anal Cancer	295
Cardiac Implantable Electronic Devices	295
Behçet’s Syndrome	294
Association between Covid-19 Vaccination and Influenza Vaccination Rates	292
Glycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes	290
Transforming Management of Opioid Use Disorder with Universal Treatment	289
Disappearing Data at the U.S. Federal Government	288
Advanced HIV as a Neglected Disease	288
Aspergillus Infections	285
Gustatory Hyperhidrosis after Parotid Surgery	284
Medication-Associated Diethylene Glycol Mass Poisoning — A Preventable Cause of Illness and Death	282
Apolipoprotein A1 Infusions and Cardiovascular Outcomes after Acute Myocardial Infarction	281
A Zoonotic Henipavirus in Febrile Patients in China	280
A Dual-Chamber Leadless Pacemaker	280
Emodepside for Trichuris trichiura and Hookworm Infection	279
Resistance Mutations in SARS-CoV-2 Delta Variant after Sotrovimab Use	278
Immune Checkpoint Inhibitors — The Need for Innovation	278
The IARC Perspective on Cervical Cancer Screening	277
Chronic Traumatic Encephalopathy in the Brains of Military Personnel	276
Waning Immunity after the BNT162b2 Vaccine in Israel	276
Acute Myeloid Leukemia Case after Gene Therapy for Sickle Cell Disease	276
Phase 1–2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B	274
Safety and Efficacy of Denosumab for Fibrous Dysplasia of Bone	271
Bivalent Covid-19 Vaccines — A Cautionary Tale	269
Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer	268
Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma	267
Betibeglogene Autotemcel Gene Therapy for Non–β ⁰ /β ⁰ Genotype β-Thalassemia	264
Artificial Intelligence in Medicine	264
Catheter Ablation in End-Stage Heart Failure with Atrial Fibrillation	264
Monkeypox	261
Methylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial	260
GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma	259
Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction	259
A Phase 2 Randomized Trial of Survodutide in MASH and Fibrosis	258
Early Outpatient Treatment for Covid-19 with Convalescent Plasma	258
Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults	256
Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension	254
Risk of Second Tumors and T-Cell Lymphoma after CAR T-Cell Therapy	254
Autoantibodies Targeting Nephrin in Podocytopathies	253
Transcatheter Valve Replacement in Severe Tricuspid Regurgitation	252
Effectiveness of Bivalent Boosters against Severe Omicron Infection	249
TAVR for Asymptomatic Severe Aortic Stenosis	249
Health Care in an Evolving Immigration Landscape — Providing Care while Upholding the Law	249
Aspiration Thrombectomy for Coronary Stent Thrombosis	249
Transparency and the Doctor–Patient Relationship — Rethinking Conflict-of-Interest Disclosures	248
Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant	246
A “Fluid” Diagnosis	246
Case 37-2021: A 60-Year-Old Man with Fevers, Fatigue, Arthralgias, a Mouth Ulcer, and a Rash	246