OOIR: Observatory of International Research

Papers

(The median citation count of New England Journal of Medicine is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Screening for Prostate Cancer	4573
Long-Term Outcomes of Resynchronization–Defibrillation for Heart Failure	2991
Debating Race and the Diagnosis of Anemia — How Medicine Moved Away from Race-Based Standards	2458
Case 18-2025: A 63-Year-Old Woman with Dyspnea on Exertion	2375
Turning CMS into a Health Technology Assessment Organization	2298
A Modern Therapy for an Ancient Disease	2173
Hiding in Plain Sight	1831
Nonketotic Hyperglycemic Hemichorea	1596
Ten Years of Incidental, Secondary, and Actionable Findings	1482
Rethinking Shadowing for Aspiring Physicians	1447
A Trial of Trimethoprim–Sulfamethoxazole in Pregnancy to Improve Birth Outcomes	1374
Redefining Lung Cancer Therapy — A Long-Awaited Shift in Strategy	1336
SENIOR-RITA — Is It All about Angiography?	1023
Cerebral Embolic Protection during TAVI	1020
Audio Interview: Dissecting the Host Response to SARS-CoV-2	1005
Listening and Responding to Community Voices — The Community Wellness HUB	971
Automated Insulin Pump in Type 2 Diabetes	956
Smallpox at the Siege of Boston, November 1775–March 1776	949
A Swell Diagnosis	920
Postacute Sequelae of SARS-CoV-2 Infection in Several Eras	908
Race-Based Diagnosis, Part 1 — ITT Episode 33	893
Investigating Injustices in the Journal ’s History, Part 2	891
Hemotympanum with a Basilar Skull Fracture	872
Secondary Hypertrophic Osteoarthropathy	866
Intravenous Levothyroxine for Unstable Brain-Dead Heart Donors	841

Psychosocial Functioning in Transgender Youth after 2 Years of Hormones	814
Testing for Arginine Vasopressin Deficiency	813
Case 40-2022: A 38-Year-Old Man with Exertional Chest Discomfort	812
The Muffin Question	811
Bilothorax	792
Audio Interview: Assessing Bivalent Vaccines against Covid-19	788
Nationwide, Couple-Based Genetic Carrier Screening	787
Poet as Patient	783
Navigating and Communicating about Serious Illness and End of Life	767
Liver Transplantation for Mahvash Disease, an Inborn Error of Metabolism	752
Adrenal Involvement in Disseminated Histoplasmosis	745
Multicentric Reticulohistiocytosis	718
Black Dot Tinea Capitis	710
Timing Is Everything — Evidence for When to Perform Complete Revascularization in STEMI	705
Convalescent Rash of Dengue	698
Bumps in the Road	696
Prolonging Cellular Life after Hypoxic Death	687
Breaking the Sacred Promise	681
Gazing into a Crystal Ball	681
Cholelithiasis, Cholecystitis, and Choledocholithiasis	681
Pistachio Ice Cream	664
Minocycline-Induced Hyperpigmentation	658
Left Atrial Appendage Closure — Another Overused Method in Cardiology?	648
Ménétrier’s Disease	644
Bismuth Subsalicylate Poisoning	644
More Options for Gene Editing in Hemoglobinopathies	644
Kidney Injury and Hair-Straightening Products Containing Glyoxylic Acid	642
A Case of Cervical Ectopic Pregnancy after the Dobbs Decision	641
Optical Coherence Tomography and Eye Care	636
Paget’s Disease of the Breast	625
Asciminib in Newly Diagnosed Chronic Myeloid Leukemia	624
From the Eyeball Test to the Algorithm — Quality of Life, Disability Status, and Clinical Decision Making in Surgery	623
Modifiable Risk Factors and Cardiovascular Outcomes	619
Preparing for the Next Pandemic — Expanding and Coordinating Global Regulatory Capacity	617
Targeting CSF1R in Chronic GVHD — Lessons in Translation	605
Genetic Variation in Clinical Cohorts	601
Effect of a Reduced PCV10 Dose Schedule on Pneumococcal Carriage in Vietnam	596
Striking a Balance — Advancing Physician Collective-Bargaining Rights and Patient Protections	594
Threatening the Future of Global Health — NIH Policy Changes on International Research Collaborations	590
Gantenerumab in Early Alzheimer’s Disease	588
Perioperative Durvalumab in Bladder Cancer	585
Tenecteplase for Stroke — Opening the Window?	582
Out of Pocket Getting Out of Hand — Reducing the Financial Toxicity of Rapidly Approved Drugs	546
Exclusion of Elective Care from Hospital Financial Assistance Policies — Arresting a Troubling Development	528
Spontaneous Intracranial Hypotension	522
Malnutrition in Adults	520
U.S. Law and Discrimination in Health Care	513
Mucosal IgA against SARS-CoV-2 Omicron Infection	508
Virotherapy for Brain Tumors — Defining the Path to Success	501
Measurable Residual Disease–Guided Therapy for Chronic Lymphocytic Leukemia	498

Therapy for Atrial Fibrillation in Patients with Drug-Eluting Stents	495
Telitacicept for IgA Nephropathy — Interim Analysis of a Phase 3 Trial	495
Childhood Risk Factors and Adult Cardiovascular Events	495
Early Active Mobilization during Mechanical Ventilation in the ICU	488
Overcoming Resistance — Omission of Radiotherapy for Low-Risk Breast Cancer	488
Meet the Equation	471
HFpEF Explained — Prevalence, New Advances, and How to Diagnose	452
Reteplase versus Alteplase for Acute Ischemic Stroke	451
Gene Therapy with Fidanacogene Elaparvovec in Adults with Hemophilia B	451
Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk	446
Evidence-Based Work Design — Bridging the Divide	443
A Threat to Evidence-Based Vaccine Policy and Public Health Security at the FDA	443
Number Needed to Treat	442
Transformative Research in Cystic Fibrosis	438
Selective Digestive Decontamination — Finding the Way Forward	437
Monoclonal Antibodies for Malaria	437
Permethrin-Treated Baby Wraps for the Prevention of Malaria	434
How to Save a Life	430
Monoclonal Antibodies in the Pathogenesis of Heparin-Induced Thrombocytopenia	426
Zilebesiran for Hypertension	425
Hypothermia or Machine Perfusion in Kidney Donors	424
Middle Meningeal Artery Embolization for Subdural Hematoma	423
BCMA-Targeted T-Cell Engager for Autoimmune Hemolytic Anemia after CD19 CAR T-Cell Therapy	420
Nutritional Support for Moderate-to-Late–Preterm Infants — A Randomized Trial	419
Understanding How Aspirin Prevents Metastasis	418
Use of Wastewater for Mpox Outbreak Surveillance in California	415
Periprosthetic Joint Infection	414
Navigating and Communicating about Serious Illness and End of Life	414
Belantamab Mafodotin, Bortezomib, and Dexamethasone for Multiple Myeloma	413
Teclistamab plus Daratumumab in Relapsed or Refractory Multiple Myeloma	411
Haloperidol for the Treatment of Delirium in ICU Patients	404
Bronchiectasis — A Clinical Review	403
War and Famine	402
Sacituzumab Govitecan in Untreated, Advanced Triple-Negative Breast Cancer	402
Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes	397
Mepolizumab to Prevent Exacerbations of COPD with an Eosinophilic Phenotype	397
Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer	394
Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction	393
Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer	391
Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD	390
First-Line Venetoclax Combinations in Chronic Lymphocytic Leukemia	385
Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts	383
A Tale of Two Diseases	382
Tuberculous Meningitis — New Approaches Needed	379
Functional Dyspepsia	378
Trials for Managing Acute Pain — A Clinically Meaningful Small Effect Size?	377
NEJM at AHA — Routine Spironolactone in Acute Myocardial Infarction	374
Autoantibodies Targeting Nephrin in Podocytopathies	374
Integration of Tobacco-Cessation Interventions into Tuberculosis and HIV Care	371
Prevalence of Mismatch-Repair Deficiency in Rectal Adenocarcinomas	368
Guidance on Energy and Macronutrients across the Life Span	368
Amivantamab–Lazertinib in EGFR -Mutated Advanced NSCLC	367
Dengue Suppression by Male Wolbachia-Infected Mosquitoes	367
Moving the Needle on Alzheimer’s Disease with an Anti-Oligomer Antibody	366
Vocal-Cord Polyp Causing Airway Obstruction	364
Medication-Associated Diethylene Glycol Mass Poisoning — A Preventable Cause of Illness and Death	364
Immunogenicity and Safety of vYF, a Yellow Fever Vaccine — A Phase 2 Trial	363
Invasive Strategy for Older Patients with MI	360
Elective Cesarean Section for Maternal Preference	358
Focused Cardiac Ultrasonography for Right Ventricular Size and Systolic Function	355
Fulminant Viral Myocarditis Associated with Thogotovirus	352
Covid-19 Surveillance Testing in Nursing Homes	345
Increasing Firearm-Related Deaths among U.S. Black Rural Youths	343
Leveraging School Systems as Data Partners to Advance Health Equity	342
Trends in Youth-Onset Type 2 Diabetes, 2013–2024	339
Closing the Evidence Gap for Drugs in Children — Measures to Strengthen the Pediatric Research Equity Act	334
Necrolytic Migratory Erythema	334
Cholesterol Pericarditis	333
Case 38-2024: A 22-Year-Old Woman with Headache, Fever, and Respiratory Failure	332
Crinecerfont in Adult Congenital Adrenal Hyperplasia	330
Personality Disorders	328
Case 5-2023: A 67-Year-Old Man with Interstitial Lung Disease, Fever, and Myalgias	328
Audio Interview: Rolling Out New Covid-19 Vaccines	327
HIV Prevention and the 340B Drug Pricing Program	326
Medication for Gastroesophageal Reflux Disease in Infants	321
Japanese Spotted Fever	321
Broken Both Ways	317
Convalescent Plasma for Covid-19–Induced ARDS	313
What We Don’t Know about School Shooter Drills	313
Case 21-2023: A 61-Year-Old Man with Eyelid Swelling	312

Intravenous Amino Acids and Kidney Protection	310
Felzartamab in Antibody-Mediated Rejection	308
Case 26-2022: A 48-Year-Old Woman with Cystic Lung Disease	306
Routine Removal of Inferior Vena Cava Filters	306
End of a Declared Public Health Emergency — Implications for U.S. Emergency Use Authorizations	304
Audio Interview: Ending the Covid-19 Public Health Emergency	304
Diagnostic Aspirations	304
Guilty	303
PD-1 and PD-L1 Blockade plus Chemotherapy in Endometrial Cancer	302
Case 39-2023: A 43-Year-Old Woman with Chronic Diarrhea, Hair Loss, and Nail and Skin Changes	301
Randomized Trial of Targeted Indoor Spraying to Prevent Aedes-Borne Diseases	300
Chylothorax	300
Expect With Me — Group Prenatal Care to Reduce Disparities	300
A Preview of the Dangerous Future of Abortion Bans — Texas Senate Bill 8	299
Audio Interview: Ending the Covid-19 Emergency	299
Academic Freedom in America — In Support of Institutional Voices	298
New Perioperative Strategy in Gastric Cancer	295
Bivalent Covid-19 Vaccines — A Cautionary Tale	294
Mucormycosis	293
Compared with What? Measuring AI against the Health Care We Have	289
Mycoplasma-Induced Rash and Mucositis	286
Immune Checkpoint Inhibitors — The Need for Innovation	286
FINEARTS-HF — The Latest Masterpiece for MRAs in Heart Failure	286
Ondansetron after ED Visits in Children with Gastroenteritis	286
Emodepside for Trichuris trichiura and Hookworm Infection	284
Laryngeal Candidiasis	282
A Dual-Chamber Leadless Pacemaker	282
Neurovascular Complications of Iatrogenic Fusarium solani Meningitis	282
Genetically Modified Porcine-to-Human Cardiac Xenotransplantation	281
Can AI Solve Primary Care?	280
Pegylated Interferon Lambda for Covid-19	279
The Increasing Incidence of Early-Onset Colorectal Cancer	276
Water-Based and Waterless Surgical Scrub Techniques	275
Phase 1–2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B	275
The Death of an Unlikable Man	275
A Physician Attack on the FDA — Will the Supreme Court Reduce Access to Mifepristone?	274
Advanced HIV as a Neglected Disease	271
Safety and Efficacy of Denosumab for Fibrous Dysplasia of Bone	270
Helicobacter pylori , Homologous-Recombination Genes, and Gastric Cancer	269
Pretomanid in the Treatment of Patients with Tuberculosis in the United States	267
Unpacking the Ordinary	267
Five-Year Outcomes of the Danish Cardiovascular Screening (DANCAVAS) Trial	265
Targeting Lipoprotein(a) — the Next Frontier in Cardiovascular Disease	263
Chronic Traumatic Encephalopathy in the Brains of Military Personnel	262
Hospital Problems	261
Disappearing Data at the U.S. Federal Government	259
Ultraprocessed Food on an Ultrafast Track	258
A Zoonotic Henipavirus in Febrile Patients in China	257
Cardiovascular Risk Factors — Hypertension	257
Retraction: Bronchial Casts from Inhalation of Forest-Fire Smoke. N Engl J Med 2026;394:1634.	256
Making Long-Term Oxygen Therapy Less Burdensome	253
Treatment of Anal High-Grade Squamous Intraepithelial Lesions to Prevent Anal Cancer	252
Association between Covid-19 Vaccination and Influenza Vaccination Rates	251
Atrial Fibrillation — What Is It and How Is It Treated?	250
Transforming Management of Opioid Use Disorder with Universal Treatment	249
Criminalizing Homelessness — The Grants Pass, Oregon, Supreme Court Case	248
Genital Herpes Zoster	247
Gastric Syphilis	247
Postherpetic Abdominal Pseudohernia	247
Transfusion Strategy in Myocardial Infarction and Anemia	246
Gustatory Hyperhidrosis after Parotid Surgery	246
Public Health’s Role in a Post- Dobbs World — The New York City Abortion Access Hub	244
In Vitro Efficacy of Antiviral Agents against Omicron Subvariant BA.4.6	243
Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension	242
Occupational Health and Safety on the Chopping Block — What’s at Stake?	242
Apolipoprotein A1 Infusions and Cardiovascular Outcomes after Acute Myocardial Infarction	242
Extending Cancer Survival with Exercise — Time for Oncology to Act	242
The Risks of Normalizing Parental Vaccine Hesitancy	242
SGLT2 Inhibitors and False Positive Toxicology Tests	241
Immediate or Deferred Nonculprit-Lesion PCI in Myocardial Infarction	241
Artificial Intelligence in Medicine	239
GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma	237
Monkeypox	237
Phase 3 Trial of Inhaled Molgramostim in Autoimmune Pulmonary Alveolar Proteinosis	236
Behçet’s Syndrome	235
Glycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes	234
Risk of Second Tumors and T-Cell Lymphoma after CAR T-Cell Therapy	232
Selpercatinib in Early-Stage RET Fusion–Positive Non–Small-Cell Lung Cancer	232
Cardiac Implantable Electronic Devices	232
Methylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial	231
A Phase 2 Randomized Trial of Survodutide in MASH and Fibrosis	231
Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma	231
Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction	231
Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults	230
Catheter Ablation in End-Stage Heart Failure with Atrial Fibrillation	230
“Putting America First” — Undermining Health for Populations at Home and Abroad	228
Small Step or Giant Leap? Expanding the Acute Stroke Thrombolysis Window to 24 Hours	228
Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity	228
Transcatheter Valve Replacement in Severe Tricuspid Regurgitation	227
Aspiration Thrombectomy for Coronary Stent Thrombosis	227
Autoantibodies Targeting Nephrin in Podocytopathies	227
Daily Urinary Sodium and Potassium Excretion and Cardiovascular Risk	226
Case 1-2023: A 49-Year-Old Man with Hypokalemia and Paranoia	226
Loosening the Shackles of Depression	226
NEJM at ESMO — Preoperative Chemoradiotherapy for Resectable Gastric Cancer	225