OOIR: Observatory of International Research

Papers

(The median citation count of New England Journal of Medicine is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Hyperpigmentation in Vitamin B ₁₂ Deficiency	3129
Tenecteplase for Stroke — Opening the Window?	2845
Designing Cures 2.0 — From Corridors to Cornerstones	2395
Adrenal Involvement in Disseminated Histoplasmosis	2392
Nasal Cauterization with Silver Nitrate for Recurrent Epistaxis	2163
Preparing for the Next Pandemic — Expanding and Coordinating Global Regulatory Capacity	1945
Black Dot Tinea Capitis	1847
U.S. Law and Discrimination in Health Care	1846
Hemotympanum with a Basilar Skull Fracture	1767
Multicentric Reticulohistiocytosis	1657
Alteplase and Thrombectomy — Not a Bridge to Dismantle	1637
Bismuth Subsalicylate Poisoning	1611
Hiding in Plain Sight	1598
Convalescent Rash of Dengue	1576
Foreign-Body Aspiration in a Child	1541
Nonketotic Hyperglycemic Hemichorea	1487
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors for Anemia in CKD	1364
STEP 1 for Effective Weight Control — Another First Step?	1252
Testing for Arginine Vasopressin Deficiency	1250
HIPAA at 25 — A Work in Progress	1232
Use of Polygenic Scores to Select Embryos	1221
Investigating Injustices in the Journal ’s History, Part 2	1198
Ten Years of Incidental, Secondary, and Actionable Findings	1198
Paget’s Disease of the Breast	1170
Intravenous Levothyroxine for Unstable Brain-Dead Heart Donors	1145

Poet as Patient	1123
Liver Transplantation for Mahvash Disease, an Inborn Error of Metabolism	1123
Modifiable Risk Factors and Cardiovascular Outcomes	1044
Race-Based Diagnosis, Part 1 — ITT Episode 33	1008
Primaquine and Plasmodium vivax Malaria Recurrence in Brazil	1004
Childhood Risk Factors and Adult Cardiovascular Events	996
Ruxolitinib for Chronic Graft-versus-Host Disease	978
Maintenance or Discontinuation of Antidepressants in Primary Care	930
Case 40-2022: A 38-Year-Old Man with Exertional Chest Discomfort	906
Audio Interview: Assessing Bivalent Vaccines against Covid-19	901
Early Active Mobilization during Mechanical Ventilation in the ICU	875
Screening for Prostate Cancer	854
A Modern Therapy for an Ancient Disease	824
The Muffin Question	810
Audio Interview: Dissecting the Host Response to SARS-CoV-2	796
Bumps in the Road	795
Early Treatment with Sotrovimab for Covid-19	780
Gingival Infiltration in Acute Monocytic Leukemia	768
Covid-19 Infections in Vaccinated Health Care Workers	768
Perioperative Durvalumab in Bladder Cancer	766
Bilothorax	761
Postacute Sequelae of SARS-CoV-2 Infection in Several Eras	740
Targeting CSF1R in Chronic GVHD — Lessons in Translation	727
Freedom of Speech	725
Rethinking Shadowing for Aspiring Physicians	720
Psychosocial Functioning in Transgender Youth after 2 Years of Hormones	720
Ménétrier’s Disease	717
Middle Meningeal Artery Embolization for Subdural Hematoma	715
Prolonging Cellular Life after Hypoxic Death	711
Long-Term Outcomes of Resynchronization–Defibrillation for Heart Failure	709
Nationwide, Couple-Based Genetic Carrier Screening	682
A Swell Diagnosis	673
Timing Is Everything — Evidence for When to Perform Complete Revascularization in STEMI	651
Out of Pocket Getting Out of Hand — Reducing the Financial Toxicity of Rapidly Approved Drugs	651
Asciminib in Newly Diagnosed Chronic Myeloid Leukemia	648
How Can We Fully Realize SNAP’s Health Benefits?	645
Navigating and Communicating about Serious Illness and End of Life	635
Zilebesiran for Hypertension	624
Threatening the Future of Global Health — NIH Policy Changes on International Research Collaborations	624
Breaking the Sacred Promise	614
Vaccine Breakthrough Infections with SARS-CoV-2 Variants	613
Catching Up on REMs	612
Optical Coherence Tomography and Eye Care	611
Receipt of mRNA Vaccine against Covid-19 and Myocarditis	610
Turning CMS into a Health Technology Assessment Organization	602
Overcoming Resistance — Omission of Radiotherapy for Low-Risk Breast Cancer	601
Secondary Hypertrophic Osteoarthropathy	591
Nutritional Support for Moderate-to-Late–Preterm Infants — A Randomized Trial	583
Effect of a Reduced PCV10 Dose Schedule on Pneumococcal Carriage in Vietnam	581
Gastric Emptying Abnormalities in Diabetes Mellitus	580

Cholelithiasis, Cholecystitis, and Choledocholithiasis	575
Gazing into a Crystal Ball	574
Code Switch	572
Malnutrition in Adults	569
Race in Medicine — Genetic Variation, Social Categories, and Paths to Health Equity	568
SENIOR-RITA — Is It All about Angiography?	563
Automated Insulin Pump in Type 2 Diabetes	561
The Importance of Context in Covid-19 Vaccine Safety	556
Kidney Injury and Hair-Straightening Products Containing Glyoxylic Acid	553
Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile	545
Mucosal IgA against SARS-CoV-2 Omicron Infection	542
Automatic Insurance Policies — Important Tools for Preventing Coverage Loss	539
Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk	538
Striking a Balance — Advancing Physician Collective-Bargaining Rights and Patient Protections	537
Evidence-Based Work Design — Bridging the Divide	536
Bronchiectasis — A Clinical Review	528
Hypothermia or Machine Perfusion in Kidney Donors	526
Virotherapy for Brain Tumors — Defining the Path to Success	518
Use of Wastewater for Mpox Outbreak Surveillance in California	516
Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial	514
Empagliflozin in Heart Failure with a Preserved Ejection Fraction	509
Reteplase versus Alteplase for Acute Ischemic Stroke	508
Mepolizumab to Prevent Exacerbations of COPD with an Eosinophilic Phenotype	500
Striving for Diversity in Research Studies	499
Misogyny in Medicine	497
Racial Inequality in Prescription Opioid Receipt — Role of Individual Health Systems	491
Monoclonal Antibodies for Malaria	490
Fever of Unknown Origin	489
Implanted System for Orthostatic Hypotension in Multiple-System Atrophy	486
First-Line Venetoclax Combinations in Chronic Lymphocytic Leukemia	483
Belantamab Mafodotin, Bortezomib, and Dexamethasone for Multiple Myeloma	483
Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction	482
Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer	481
Lung Transplantation for Covid-19–Related Respiratory Failure in the United States	480
Navigating and Communicating about Serious Illness and End of Life	480
From the Eyeball Test to the Algorithm — Quality of Life, Disability Status, and Clinical Decision Making in Surgery	476
Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts	474
New Horizons in the Treatment of Osteosarcoma	467
Haloperidol for the Treatment of Delirium in ICU Patients	464
Periprosthetic Joint Infection	462
Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer	456
Gantenerumab in Early Alzheimer’s Disease	454
Gene Therapy with Fidanacogene Elaparvovec in Adults with Hemophilia B	452
Edoxaban versus Vitamin K Antagonist for Atrial Fibrillation after TAVR	444
Case 38-2024: A 22-Year-Old Woman with Headache, Fever, and Respiratory Failure	442
Disappearing Data at the U.S. Federal Government	441
Vocal-Cord Polyp Causing Airway Obstruction	436
HIV Prevention and the 340B Drug Pricing Program	436
Covid-19 Surveillance Testing in Nursing Homes	433
Audio Interview: Ending the Covid-19 Public Health Emergency	432
What We Don’t Know about School Shooter Drills	423
Audio Interview: Rolling Out New Covid-19 Vaccines	423
Case 26-2022: A 48-Year-Old Woman with Cystic Lung Disease	423
Case 21-2023: A 61-Year-Old Man with Eyelid Swelling	417
Convalescent Plasma for Covid-19–Induced ARDS	414
Water-Based and Waterless Surgical Scrub Techniques	414
Chylothorax	413
Routine Removal of Inferior Vena Cava Filters	409
HIPAA and the Leak of “Deidentified” EHR Data	405
NEJM at AHA — Routine Spironolactone in Acute Myocardial Infarction	404
FINEARTS-HF — The Latest Masterpiece for MRAs in Heart Failure	403
Medication-Associated Diethylene Glycol Mass Poisoning — A Preventable Cause of Illness and Death	401
Pretomanid in the Treatment of Patients with Tuberculosis in the United States	401
Audio Interview: The Omicron Variant of SARS-CoV-2	401
The IARC Perspective on Cervical Cancer Screening	395
Expect With Me — Group Prenatal Care to Reduce Disparities	393
Criminalizing Homelessness — The Grants Pass, Oregon, Supreme Court Case	390
PD-1 and PD-L1 Blockade plus Chemotherapy in Endometrial Cancer	388
SGLT2 Inhibitors and False Positive Toxicology Tests	386
Skeletal Fluorosis	385
Treatment of Relapsing HPV Diseases by Restored Function of Natural Killer Cells	383
Vaccine Effectiveness Studies in the Field	382
What’s in a Number? Breaking Down the Residency Match Rate	381
Gastric Syphilis	381
End of a Declared Public Health Emergency — Implications for U.S. Emergency Use Authorizations	380
Helicobacter pylori , Homologous-Recombination Genes, and Gastric Cancer	378
Autoantibodies Targeting Nephrin in Podocytopathies	378
Laryngeal Candidiasis	376
Broken Both Ways	375
Guidance on Energy and Macronutrients across the Life Span	373

The Increasing Incidence of Early-Onset Colorectal Cancer	372
Medication for Gastroesophageal Reflux Disease in Infants	371
Making Long-Term Oxygen Therapy Less Burdensome	369
Intravenous Amino Acids and Kidney Protection	366
Increasing Firearm-Related Deaths among U.S. Black Rural Youths	366
Diagnostic Aspirations	366
Risks and Benefits of Janus Kinase Inhibitors in Rheumatoid Arthritis — Past, Present, and Future	365
Academic Freedom in America — In Support of Institutional Voices	362
Cholesterol Pericarditis	362
Genital Herpes Zoster	358
Crinecerfont in Adult Congenital Adrenal Hyperplasia	357
Pegylated Interferon Lambda for Covid-19	355
Small Step or Giant Leap? Expanding the Acute Stroke Thrombolysis Window to 24 Hours	353
Ferning in Nasal Mucus	352
Benefits and Risks of Iron Interventions in Infants in Bangladesh	351
Genetically Modified Porcine-to-Human Cardiac Xenotransplantation	351
Public Health’s Role in a Post- Dobbs World — The New York City Abortion Access Hub	351
Japanese Spotted Fever	350
Gustatory Hyperhidrosis after Parotid Surgery	350
Guilty	347
Atrial Fibrillation — What Is It and How Is It Treated?	344
Moving the Needle on Alzheimer’s Disease with an Anti-Oligomer Antibody	343
Targeting HER2 -Mutant NSCLC — The Light Is On	342
Booster Doses and Prioritizing Lives Saved	339
Felzartamab in Antibody-Mediated Rejection	336
Dermatomyositis	336
Case 5-2023: A 67-Year-Old Man with Interstitial Lung Disease, Fever, and Myalgias	336
Hospital Problems	334
Trials for Managing Acute Pain — A Clinically Meaningful Small Effect Size?	332
Targeting Lipoprotein(a) — the Next Frontier in Cardiovascular Disease	332
A Physician Attack on the FDA — Will the Supreme Court Reduce Access to Mifepristone?	329
Mycoplasma-Induced Rash and Mucositis	328
Neurovascular Complications of Iatrogenic Fusarium solani Meningitis	327
Prevalence of Mismatch-Repair Deficiency in Rectal Adenocarcinomas	324
Focused Cardiac Ultrasonography for Right Ventricular Size and Systolic Function	323
Tuberculous Meningitis — New Approaches Needed	323
“Putting America First” — Undermining Health for Populations at Home and Abroad	317
Transforming Management of Opioid Use Disorder with Universal Treatment	317
Invasive Strategy for Older Patients with MI	316
Artificial Intelligence in Medicine	315
Case 39-2023: A 43-Year-Old Woman with Chronic Diarrhea, Hair Loss, and Nail and Skin Changes	314
Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia	312
Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19	311
Betibeglogene Autotemcel Gene Therapy for Non–β ⁰ /β ⁰ Genotype β-Thalassemia	310
Early Outpatient Treatment for Covid-19 with Convalescent Plasma	309
Five-Year Outcomes of the Danish Cardiovascular Screening (DANCAVAS) Trial	309
A Dual-Chamber Leadless Pacemaker	307
Phase 1–2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B	306
Advanced HIV as a Neglected Disease	304
Postherpetic Abdominal Pseudohernia	301
Bivalent Covid-19 Vaccines — A Cautionary Tale	299
Safety and Efficacy of Denosumab for Fibrous Dysplasia of Bone	298
A Preview of the Dangerous Future of Abortion Bans — Texas Senate Bill 8	297
Glycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes	296
Plasma Therapy to Prevent Severe Covid-19 in Older Adults	295
A Phase 2 Randomized Trial of Survodutide in MASH and Fibrosis	294
Resistance Mutations in SARS-CoV-2 Delta Variant after Sotrovimab Use	294
Acute Myeloid Leukemia Case after Gene Therapy for Sickle Cell Disease	290
The Death of an Unlikable Man	290
Apolipoprotein A1 Infusions and Cardiovascular Outcomes after Acute Myocardial Infarction	290
Methylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial	289
Transfusion Strategy in Myocardial Infarction and Anemia	289
Audio Interview: Ending the Covid-19 Emergency	287
Personality Disorders	287
Monkeypox	284
Aspergillus Infections	284
Cardiac Implantable Electronic Devices	281
Compared with What? Measuring AI against the Health Care We Have	281
In Vitro Efficacy of Antiviral Agents against Omicron Subvariant BA.4.6	281
Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction	280
Association between Covid-19 Vaccination and Influenza Vaccination Rates	276
Waning Immunity after the BNT162b2 Vaccine in Israel	275
Immune Checkpoint Inhibitors — The Need for Innovation	273
Behçet’s Syndrome	272
Transcatheter Valve Replacement in Severe Tricuspid Regurgitation	272
Risk of Second Tumors and T-Cell Lymphoma after CAR T-Cell Therapy	271
Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19	269
Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension	269
A Zoonotic Henipavirus in Febrile Patients in China	269
Autoantibodies Targeting Nephrin in Podocytopathies	267
Chronic Traumatic Encephalopathy in the Brains of Military Personnel	265
Emodepside for Trichuris trichiura and Hookworm Infection	264
Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma	264
Treatment of Anal High-Grade Squamous Intraepithelial Lesions to Prevent Anal Cancer	263
The Risks of Normalizing Parental Vaccine Hesitancy	262
Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults	262
Catheter Ablation in End-Stage Heart Failure with Atrial Fibrillation	259
GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma	258
Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer	256
Changing the Orbit around Percutaneous Coronary Intervention for Stable Angina	255
Is Xenotransplantation Ready for Prime Time?	254
The Evolving Challenge of Infections in Cirrhosis	253
Weighing the Risks of Lentiviral Gene Therapy for Cerebral Adrenoleukodystrophy	252
Efpeglenatide and Heart and Kidney Outcomes in Type 2 Diabetes	252
Oxygenation and Blood-Pressure Targets in the ICU after Cardiac Arrest — One Step Forward	250