OOIR: Observatory of International Research

Papers

(The TQCC of New England Journal of Medicine is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Striking a Balance — Advancing Physician Collective-Bargaining Rights and Patient Protections	3370
How Can We Fully Realize SNAP’s Health Benefits?	3294
Malnutrition in Adults	2703
Childhood Risk Factors and Adult Cardiovascular Events	2043
The Importance of Context in Covid-19 Vaccine Safety	1997
A Swell Diagnosis	1927
Gantenerumab in Early Alzheimer’s Disease	1812
Race in Medicine — Genetic Variation, Social Categories, and Paths to Health Equity	1811
Optical Coherence Tomography and Eye Care	1797
Prolonging Cellular Life after Hypoxic Death	1751
Middle Meningeal Artery Embolization for Subdural Hematoma	1639
Cholelithiasis, Cholecystitis, and Choledocholithiasis	1568
Gazing into a Crystal Ball	1556
Automated Insulin Pump in Type 2 Diabetes	1534
Foreign-Body Aspiration in a Child	1465
Catching Up on REMs	1353
Maintenance or Discontinuation of Antidepressants in Primary Care	1260
Audio Interview: Dissecting the Host Response to SARS-CoV-2	1233
Perioperative Durvalumab in Bladder Cancer	1213
Effect of a Reduced PCV10 Dose Schedule on Pneumococcal Carriage in Vietnam	1162
Asciminib in Newly Diagnosed Chronic Myeloid Leukemia	1112
Postacute Sequelae of SARS-CoV-2 Infection in Several Eras	1108
Targeting CSF1R in Chronic GVHD — Lessons in Translation	1104
Race-Based Diagnosis, Part 1 — ITT Episode 33	1022
Investigating Injustices in the Journal ’s History, Part 2	956

Tenecteplase for Stroke — Opening the Window?	941
Hemotympanum with a Basilar Skull Fracture	928
Secondary Hypertrophic Osteoarthropathy	917
Testing for Arginine Vasopressin Deficiency	884
Intravenous Levothyroxine for Unstable Brain-Dead Heart Donors	871
Psychosocial Functioning in Transgender Youth after 2 Years of Hormones	866
U.S. Law and Discrimination in Health Care	850
Case 40-2022: A 38-Year-Old Man with Exertional Chest Discomfort	818
The Muffin Question	813
Hiding in Plain Sight	803
Bilothorax	769
Audio Interview: Assessing Bivalent Vaccines against Covid-19	764
A Modern Therapy for an Ancient Disease	756
Monoclonal Antibodies for Malaria	748
Designing Cures 2.0 — From Corridors to Cornerstones	735
Nonketotic Hyperglycemic Hemichorea	732
Gingival Infiltration in Acute Monocytic Leukemia	723
Hyperpigmentation in Vitamin B ₁₂ Deficiency	723
Use of Polygenic Scores to Select Embryos	705
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors for Anemia in CKD	691
Alteplase and Thrombectomy — Not a Bridge to Dismantle	678
Ruxolitinib for Chronic Graft-versus-Host Disease	673
BCMA-Targeted T-Cell Engager for Autoimmune Hemolytic Anemia after CD19 CAR T-Cell Therapy	670
Ménétrier’s Disease	670
Rethinking Shadowing for Aspiring Physicians	664
Nationwide, Couple-Based Genetic Carrier Screening	659
Poet as Patient	657
Navigating and Communicating about Serious Illness and End of Life	654
Preparing for the Next Pandemic — Expanding and Coordinating Global Regulatory Capacity	646
Liver Transplantation for Mahvash Disease, an Inborn Error of Metabolism	625
Multicentric Reticulohistiocytosis	620
Adrenal Involvement in Disseminated Histoplasmosis	620
Zilebesiran for Hypertension	618
Black Dot Tinea Capitis	617
Ten Years of Incidental, Secondary, and Actionable Findings	614
Timing Is Everything — Evidence for When to Perform Complete Revascularization in STEMI	610
Convalescent Rash of Dengue	606
Turning CMS into a Health Technology Assessment Organization	598
Bismuth Subsalicylate Poisoning	598
Early Treatment with Sotrovimab for Covid-19	592
Covid-19 Infections in Vaccinated Health Care Workers	590
Bumps in the Road	587
Debating Race and the Diagnosis of Anemia — How Medicine Moved Away from Race-Based Standards	586
A Trial of Trimethoprim–Sulfamethoxazole in Pregnancy to Improve Birth Outcomes	579
Out of Pocket Getting Out of Hand — Reducing the Financial Toxicity of Rapidly Approved Drugs	576
Exclusion of Elective Care from Hospital Financial Assistance Policies — Arresting a Troubling Development	569
Virotherapy for Brain Tumors — Defining the Path to Success	569
Paget’s Disease of the Breast	568
Case 18-2025: A 63-Year-Old Woman with Dyspnea on Exertion	558
Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile	553

Redefining Lung Cancer Therapy — A Long-Awaited Shift in Strategy	548
Nutritional Support for Moderate-to-Late–Preterm Infants — A Randomized Trial	545
Mucosal IgA against SARS-CoV-2 Omicron Infection	531
Lung Transplantation for Covid-19–Related Respiratory Failure in the United States	530
Hypothermia or Machine Perfusion in Kidney Donors	530
Evidence-Based Work Design — Bridging the Divide	524
Long-Term Outcomes of Resynchronization–Defibrillation for Heart Failure	523
Overcoming Resistance — Omission of Radiotherapy for Low-Risk Breast Cancer	522
Measurable Residual Disease–Guided Therapy for Chronic Lymphocytic Leukemia	521
Spontaneous Intracranial Hypotension	517
Empagliflozin in Heart Failure with a Preserved Ejection Fraction	516
Receipt of mRNA Vaccine against Covid-19 and Myocarditis	511
Primaquine and Plasmodium vivax Malaria Recurrence in Brazil	508
Use of Wastewater for Mpox Outbreak Surveillance in California	507
Automatic Insurance Policies — Important Tools for Preventing Coverage Loss	503
Breaking the Sacred Promise	502
Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial	501
Screening for Prostate Cancer	500
Reteplase versus Alteplase for Acute Ischemic Stroke	498
Threatening the Future of Global Health — NIH Policy Changes on International Research Collaborations	494
Implanted System for Orthostatic Hypotension in Multiple-System Atrophy	494
Haloperidol for the Treatment of Delirium in ICU Patients	494
Kidney Injury and Hair-Straightening Products Containing Glyoxylic Acid	492
Edoxaban versus Vitamin K Antagonist for Atrial Fibrillation after TAVR	490
Early Active Mobilization during Mechanical Ventilation in the ICU	490
Bronchiectasis — A Clinical Review	487
Mepolizumab to Prevent Exacerbations of COPD with an Eosinophilic Phenotype	482
Belantamab Mafodotin, Bortezomib, and Dexamethasone for Multiple Myeloma	482
Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer	481
Modifiable Risk Factors and Cardiovascular Outcomes	478
SENIOR-RITA — Is It All about Angiography?	477
Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer	474
Gene Therapy with Fidanacogene Elaparvovec in Adults with Hemophilia B	473
New Horizons in the Treatment of Osteosarcoma	460
From the Eyeball Test to the Algorithm — Quality of Life, Disability Status, and Clinical Decision Making in Surgery	458
Navigating and Communicating about Serious Illness and End of Life	452
Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk	451
Striving for Diversity in Research Studies	447
Fever of Unknown Origin	444
Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction	438
Periprosthetic Joint Infection	436
First-Line Venetoclax Combinations in Chronic Lymphocytic Leukemia	435
Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts	425
Extending Cancer Survival with Exercise — Time for Oncology to Act	418
Disappearing Data at the U.S. Federal Government	417
Postherpetic Abdominal Pseudohernia	414
Treatment of Relapsing HPV Diseases by Restored Function of Natural Killer Cells	413
Skeletal Fluorosis	406
Criminalizing Homelessness — The Grants Pass, Oregon, Supreme Court Case	406
Association between Covid-19 Vaccination and Influenza Vaccination Rates	404
Immune Checkpoint Inhibitors — The Need for Innovation	403
Targeting Lipoprotein(a) — the Next Frontier in Cardiovascular Disease	402
Early Outpatient Treatment for Covid-19 with Convalescent Plasma	401
Acute Myeloid Leukemia Case after Gene Therapy for Sickle Cell Disease	398
Safety and Efficacy of Denosumab for Fibrous Dysplasia of Bone	390
Autoantibodies Targeting Nephrin in Podocytopathies	388
Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma	384
Five-Year Outcomes of the Danish Cardiovascular Screening (DANCAVAS) Trial	384
Guidance on Energy and Macronutrients across the Life Span	378
Mycoplasma-Induced Rash and Mucositis	376
Resistance Mutations in SARS-CoV-2 Delta Variant after Sotrovimab Use	375
GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma	374
Glycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes	374
Monkeypox	373
Case 5-2023: A 67-Year-Old Man with Interstitial Lung Disease, Fever, and Myalgias	373
HIPAA and the Leak of “Deidentified” EHR Data	373
Personality Disorders	369
Audio Interview: Rolling Out New Covid-19 Vaccines	368
Atrial Fibrillation — What Is It and How Is It Treated?	367
HIV Prevention and the 340B Drug Pricing Program	366
Japanese Spotted Fever	366
Booster Doses and Prioritizing Lives Saved	359
Benefits and Risks of Iron Interventions in Infants in Bangladesh	356
Making Long-Term Oxygen Therapy Less Burdensome	355
Academic Freedom in America — In Support of Institutional Voices	355
Medication for Gastroesophageal Reflux Disease in Infants	354
Vocal-Cord Polyp Causing Airway Obstruction	353
Chylothorax	352
Broken Both Ways	351
Convalescent Plasma for Covid-19–Induced ARDS	351

A Physician Attack on the FDA — Will the Supreme Court Reduce Access to Mifepristone?	349
Gastric Syphilis	349
Helicobacter pylori , Homologous-Recombination Genes, and Gastric Cancer	348
What We Don’t Know about School Shooter Drills	346
The Death of an Unlikable Man	345
Public Health’s Role in a Post- Dobbs World — The New York City Abortion Access Hub	345
Case 21-2023: A 61-Year-Old Man with Eyelid Swelling	345
NEJM at AHA — Routine Spironolactone in Acute Myocardial Infarction	344
Intravenous Amino Acids and Kidney Protection	344
Invasive Strategy for Older Patients with MI	342
FINEARTS-HF — The Latest Masterpiece for MRAs in Heart Failure	342
Autoantibodies Targeting Nephrin in Podocytopathies	340
Felzartamab in Antibody-Mediated Rejection	338
Risks and Benefits of Janus Kinase Inhibitors in Rheumatoid Arthritis — Past, Present, and Future	337
The Increasing Incidence of Early-Onset Colorectal Cancer	336
Routine Removal of Inferior Vena Cava Filters	336
Pretomanid in the Treatment of Patients with Tuberculosis in the United States	332
Case 26-2022: A 48-Year-Old Woman with Cystic Lung Disease	332
Diagnostic Aspirations	326
Audio Interview: Ending the Covid-19 Public Health Emergency	324
End of a Declared Public Health Emergency — Implications for U.S. Emergency Use Authorizations	319
Covid-19 Surveillance Testing in Nursing Homes	318
Hospital Problems	315
Pegylated Interferon Lambda for Covid-19	311
Trials for Managing Acute Pain — A Clinically Meaningful Small Effect Size?	310
Transfusion Strategy in Myocardial Infarction and Anemia	308
PD-1 and PD-L1 Blockade plus Chemotherapy in Endometrial Cancer	308
Guilty	308
Water-Based and Waterless Surgical Scrub Techniques	306
Expect With Me — Group Prenatal Care to Reduce Disparities	305
Case 39-2023: A 43-Year-Old Woman with Chronic Diarrhea, Hair Loss, and Nail and Skin Changes	305
Genital Herpes Zoster	305
Small Step or Giant Leap? Expanding the Acute Stroke Thrombolysis Window to 24 Hours	305
SGLT2 Inhibitors and False Positive Toxicology Tests	300
In Vitro Efficacy of Antiviral Agents against Omicron Subvariant BA.4.6	299
Increasing Firearm-Related Deaths among U.S. Black Rural Youths	299
Tuberculous Meningitis — New Approaches Needed	295
Audio Interview: Ending the Covid-19 Emergency	294
Genetically Modified Porcine-to-Human Cardiac Xenotransplantation	293
Transforming Management of Opioid Use Disorder with Universal Treatment	293
Neurovascular Complications of Iatrogenic Fusarium solani Meningitis	290
New Perioperative Strategy in Gastric Cancer	290
What’s in a Number? Breaking Down the Residency Match Rate	289
Cholesterol Pericarditis	287
“Putting America First” — Undermining Health for Populations at Home and Abroad	286
Crinecerfont in Adult Congenital Adrenal Hyperplasia	285
Targeting HER2 -Mutant NSCLC — The Light Is On	284
Gustatory Hyperhidrosis after Parotid Surgery	283
Audio Interview: The Omicron Variant of SARS-CoV-2	282
Compared with What? Measuring AI against the Health Care We Have	281
The Risks of Normalizing Parental Vaccine Hesitancy	280
Case 38-2024: A 22-Year-Old Woman with Headache, Fever, and Respiratory Failure	280
Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity	280
Moving the Needle on Alzheimer’s Disease with an Anti-Oligomer Antibody	276
Phase 3 Trial of Inhaled Molgramostim in Autoimmune Pulmonary Alveolar Proteinosis	275
Betibeglogene Autotemcel Gene Therapy for Non–β ⁰ /β ⁰ Genotype β-Thalassemia	273
Medication-Associated Diethylene Glycol Mass Poisoning — A Preventable Cause of Illness and Death	272
Phase 1–2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B	272
Methylprednisolone for Heart Surgery in Infants — A Randomized, Controlled Trial	272
Emodepside for Trichuris trichiura and Hookworm Infection	272
Prevalence of Mismatch-Repair Deficiency in Rectal Adenocarcinomas	269
Bivalent Covid-19 Vaccines — A Cautionary Tale	268
Chronic Traumatic Encephalopathy in the Brains of Military Personnel	268
Laryngeal Candidiasis	267
A Preview of the Dangerous Future of Abortion Bans — Texas Senate Bill 8	267
Aspergillus Infections	265
Cardiac Implantable Electronic Devices	265
Advanced HIV as a Neglected Disease	262
Focused Cardiac Ultrasonography for Right Ventricular Size and Systolic Function	261
The IARC Perspective on Cervical Cancer Screening	260
Artificial Intelligence in Medicine	260
Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction	260
Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension	259
A Zoonotic Henipavirus in Febrile Patients in China	258
Treatment of Anal High-Grade Squamous Intraepithelial Lesions to Prevent Anal Cancer	258
Behçet’s Syndrome	256
Risk of Second Tumors and T-Cell Lymphoma after CAR T-Cell Therapy	255
Waning Immunity after the BNT162b2 Vaccine in Israel	252
Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia	252
A Phase 2 Randomized Trial of Survodutide in MASH and Fibrosis	251
Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer	248
Apolipoprotein A1 Infusions and Cardiovascular Outcomes after Acute Myocardial Infarction	244
Transcatheter Valve Replacement in Severe Tricuspid Regurgitation	241
Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults	241
Catheter Ablation in End-Stage Heart Failure with Atrial Fibrillation	239
Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes	239
A Dual-Chamber Leadless Pacemaker	239
Changing the Orbit around Percutaneous Coronary Intervention for Stable Angina	239
Is Xenotransplantation Ready for Prime Time?	238
Loosening the Shackles of Depression	236
Focused Ultrasound Ablation in Parkinson’s Disease	235
Unleashing CRISPR on Cancer	234
Weighing the Risks of Lentiviral Gene Therapy for Cerebral Adrenoleukodystrophy	233
NEJM at ESMO — Preoperative Chemoradiotherapy for Resectable Gastric Cancer	233
NEJM at ESC — Beta Blocker Interruption or Continuation with Prior Myocardial Infarction	232