Pflugers Archiv-European Journal of Physiology

Article	Citations
Glucose transporters in brain in health and disease	246
Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease	230
The molecular mechanisms of copper metabolism and its roles in human diseases	175
Glucose transporters in the small intestine in health and disease	128
Structure, function and regulation of mammalian glucose transporters of the SLC2 family	103
Perfluorocarbon-based oxygen carriers: from physics to physiology	102
Transporters of glucose and other carbohydrates in bacteria	77
Taste transduction and channel synapses in taste buds	71
GDF15, an update of the physiological and pathological roles it plays: a review	64
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction	64
Astroglial asthenia and loss of function, rather than reactivity, contribute to the ageing of the brain	64
Glucose transporters in pancreatic islets	62
Cardiac and neuronal HCN channelopathies	57
Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application	53
Human-induced pluripotent stem cell-derived cardiomyocytes, 3D cardiac structures, and heart-on-a-chip as tools for drug research	43
Neuronal Cav3 channelopathies: recent progress and perspectives	39
De novo CACAN1D Ca2+ channelopathies: clinical phenotypes and molecular mechanism	36
Resting-state networks in the course of aging—differential insights from studies across the lifespan vs. amongst the old	36
Glucose transporters in cardiovascular system in health and disease	34
Vascular and haemodynamic issues of brain ageing	32
Long non-coding RNAs: novel regulators of cellular physiology and function	31
SGLT2 and cancer	30
The role of cGMP-signalling and calcium-signalling in photoreceptor cell death: perspectives for therapy development	30
Skeletal muscle ClC-1 chloride channels in health and diseases	29
Age-related hearing loss pertaining to potassium ion channels in the cochlea and auditory pathway	29

Nobel Prize 2020 in Chemistry honors CRISPR: a tool for rewriting the code of life	28
Common and discrete mechanisms underlying chronic pain and itch: peripheral and central sensitization	26
Neuronal α2δ proteins and brain disorders	26
Painful and painless mutations of SCN9A and SCN11A voltage-gated sodium channels	26
Metabolic implications of circadian disruption	26
Bioenergetics of the VO2 slow component between exercise intensity domains	25
The regulation of FGF23 under physiological and pathophysiological conditions	24
The conduction velocity-potassium relationship in the heart is modulated by sodium and calcium	24
Transmission at rod and cone ribbon synapses in the retina	24
Renal blood flow and oxygenation	23
Channelopathies of voltage-gated L-type Cav1.3/α1D and T-type Cav3.1/α1G Ca2+ channels in dysfunction of heart automaticity	23
Potassium homeostasis: sensors, mediators, and targets	23
Structure and dynamics of photoreceptor sensory cilia	23
Biochemistry and physiology of zebrafish photoreceptors	22
Cav1.2 channelopathies causing autism: new hallmarks on Timothy syndrome	22
Complexity of skeletal muscle degeneration: multi-systems pathophysiology and organ crosstalk in dystrophinopathy	22
Cardiac small-conductance calcium-activated potassium channels in health and disease	22
Kidney metabolism and acid–base control: back to the basics	22
Rare CACNA1A mutations leading to congenital ataxia	20
CNG channel structure, function, and gating: a tale of conformational flexibility	20
Changes in sleep EEG with aging in humans and rodents	19
A detailed characterization of the hyperpolarization-activated “funny” current (If) in human-induced pluripotent stem cell (iPSC)–derived cardiomyocytes with pacemaker activity	19
Interplay between bioenergetics and oxidative stress at normal brain aging. Aging as a result of increasing disbalance in the system oxidative stress–energy provision	19
Hyperuricemia-induced endothelial insulin resistance: the nitric oxide connection	19
Regulation of distal tubule sodium transport: mechanisms and roles in homeostasis and pathophysiology	18
Keeping the ageing brain wired: a role for purine signalling in regulating cellular metabolism in oligodendrocyte progenitors	18
Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice	18
Physiological relevance of proton-activated GPCRs	17
Transport properties in CFTR−/− knockout piglets suggest normal airway surface liquid pH and enhanced amiloride-sensitive Na+ absorption	17
Glucose transport in lymphocytes	17
The crosstalk between cardiomyocyte calcium and inflammasome signaling pathways in atrial fibrillation	17
Atrial fibrillation rhythm is associated with marked changes in metabolic and myofibrillar protein expression in left atrial appendage	16
Sirtuin 1 and endothelial glycocalyx	16
Nobel somatosensations and pain	16
Photoreceptor phosphodiesterase (PDE6): activation and inactivation mechanisms during visual transduction in rods and cones	16
Plant glucose transporter structure and function	16
Phosphate intake, hyperphosphatemia, and kidney function	16
Benzophenanthridine alkaloids suppress lung adenocarcinoma by blocking TMEM16A Ca2+-activated Cl− channels	15
Erythroid glucose transport in health and disease	15
Upregulation of transient receptor potential melastatin 4 (TRPM4) in ventricular fibroblasts from heart failure patients	14
Voltage-dependent CaV3.2 and CaV2.2 channels in nociceptive pathways	14
Myosin light chain 2 marks differentiating ventricular cardiomyocytes derived from human embryonic stem cells	14
The role of calcium homeostasis remodeling in inherited cardiac arrhythmia syndromes	14
TRPA1 gene variants hurting our feelings	14
TRPM4 non-selective cation channel in human atrial fibroblast growth	14
Tissue chaperoning—the expanded functions of fetuin-A beyond inhibition of systemic calcification	14
TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei	14
SLC9A4 in the organum vasculosum of the lamina terminalis is a [Na+] sensor for the control of water intake	13
Human-induced pluripotent stem cells as models for rare cardiovascular diseases: from evidence-based medicine to precision medicine	13
Defective autophagy in vascular smooth muscle cells increases passive stiffness of the mouse aortic vessel wall	13

Ca2+ mishandling and mitochondrial dysfunction: a converging road to prediabetic and diabetic cardiomyopathy	13
Regulation of retinal membrane guanylyl cyclase (RetGC) by negative calcium feedback and RD3 protein	13
Endogenous ion channels expressed in human embryonic kidney (HEK-293) cells	13
MiR-221-3p regulates the microvascular dysfunction in diabetic retinopathy by targeting TIMP3	13
Regulation of cardiovascular calcium channel activity by post-translational modifications or interacting proteins	13
Sex difference in kidney electrolyte transport III: Impact of low K intake on thiazide-sensitive cation excretion in male and female mice	12
Spontaneous recovery, time course, and circadian influence on habituation of the cardiovascular responses to repeated restraint stress in rats	12
Deletion of the transcription factor Prox-1 specifically in the renal distal convoluted tubule causes hypomagnesemia via reduced expression of TRPM6 and NCC	12
Olfactory impairment in men and mice related to aging and amyloid-induced pathology	12
Is carbonyl/AGE/RAGE stress a hallmark of the brain aging?	12
Regulation of mitochondrial temperature in health and disease	12
Cav1.4 dysfunction and congenital stationary night blindness type 2	12
Role of vitamins in the metabolic syndrome and cardiovascular disease	12
Cav2.3 R-type calcium channels: from its discovery to pathogenic de novo CACNA1E variants: a historical perspective	12
Mechanisms underlying pathological Ca2+ handling in diseases of the heart	12
Functional subgroups of rat and human sensory neurons: a systematic review of electrophysiological properties	12
TASK channels: channelopathies, trafficking, and receptor-mediated inhibition	11
Soluble αKlotho downregulates Orai1-mediated store-operated Ca2+ entry via PI3K-dependent signaling	11
Cellular and systemic mechanisms for glucose sensing and homeostasis	11
Towards the clinical translation of optogenetic skeletal muscle stimulation	11
Ketoprofen alleviates diet-induced obesity and promotes white fat browning in mice via the activation of COX-2 through mTORC1-p38 signaling pathway	11
Paradigm shift: new concepts for HCN4 function in cardiac pacemaking	11
MiRNA-190 exerts neuroprotective effects against ischemic stroke through Rho/Rho-kinase pathway	11
The TRPV3 channel of the bovine rumen: localization and functional characterization of a protein relevant for ruminal ammonia transport	11
Presynaptic GABAB receptor–mediated network excitation in the medial prefrontal cortex of Tsc2+/- mice	11
14–3-3 protein regulation of excitation–contraction coupling	10
Olfactory signals from the main olfactory bulb converge with taste information from the chorda tympani nerve in the agranular insular cortex of rats	10
Cardiac adaptation and cardioprotection against arrhythmias and ischemia-reperfusion injury in mammalian hibernators	10
Pathological activation of CaMKII induces arrhythmogenicity through TRPM4 overactivation	10
Aggressive migration in acidic pH of a glioblastoma cancer stem cell line in vitro is independent of ASIC and KCa3.1 ion channels, but involves phosphoinositide 3-kinase	10
The erythropoietin receptor expressed in skeletal muscle is essential for mitochondrial biogenesis and physiological exercise	10
UMOD and the architecture of kidney disease	10
DCLK1 inhibition attenuates tumorigenesis and improves chemosensitivity in esophageal squamous cell carcinoma by inhibiting β-catenin/c-Myc signaling	10
Respiratory influence on brain dynamics: the preponderant role of the nasal pathway and deep slow regime	10
Altered functional properties of a missense variant in the TRESK K+ channel (KCNK18) associated with migraine and intellectual disability	10
Single nephron glomerular filtration rate measured by linescan multiphoton microscopy compared to conventional micropuncture	10
Light responses of mammalian cones	10
Peripheral receptors and neuromediators involved in the antihyperalgesic effects of acupuncture: a state-of-the-art review	10
Increasing whole-body energetic stress does not augment fasting-induced changes in human skeletal muscle	9
The importance of kidney calcium handling in the homeostasis of extracellular fluid calcium	9
Pharmacological inhibitors of the cystic fibrosis transmembrane conductance regulator exert off-target effects on epithelial cation channels	9
Acute and chronic effects of physical exercise on IgA and IgG levels and susceptibility to upper respiratory tract infections: a systematic review and meta-analysis	9
Excitation-contraction coupling and calcium release in atrial muscle	9
E-cigarette effects on vascular function in animals and humans	9
Acute intracerebroventricular injection of chemerin-9 increases systemic blood pressure through activating sympathetic nerves via CMKLR1 in brain	9
Fount, fate, features, and function of renal erythropoietin-producing cells	9
Elevated ROS depress mitochondrial oxygen utilization efficiency in cardiomyocytes during acute hypoxia	9
Functional compartmentalization of photoreceptor neurons	9
Adaptive response of the murine collecting duct to alkali loading	9
Structural aspects of rod opsin and their implication in genetic diseases	9
Lipid metabolic reprogramming by hypoxia-inducible factor-1 in the hypoxic tumour microenvironment	9
Decreased KLHL3 expression is involved in the activation of WNK-OSR1/SPAK-NCC cascade in type 1 diabetic mice	8
Sodium retention in nephrotic syndrome is independent of the activation of the membrane-anchored serine protease prostasin (CAP1/PRSS8) and its enzymatic activity	8
Respiratory entrainment of units in the mouse parietal cortex depends on vigilance state	8
Interleukin-1β in hypothalamic paraventricular nucleus mediates excitatory renal reflex	8
Controlling neuronal assemblies: a fundamental function of respiration-related brain oscillations in neuronal networks	8
Importance of evaluating protein glycosylation in pluripotent stem cell-derived cardiomyocytes for research and clinical applications	8
Bicarbonate permeation through anion channels: its role in health and disease	8
Protection of kidney function and tissue integrity by pharmacologic use of natriuretic peptides and neprilysin inhibitors	8
Mineralocorticoid receptor-antagonism prevents COVID-19-dependent glycocalyx damage	8
Breathing modulates gamma synchronization across species	8
( −)-Epicatechin and cardiometabolic risk factors: a focus on potential mechanisms of action	8
Metabolic mechanisms of acute proximal tubular injury	8
A special issue on glucose transporters in health and disease	7
An alternative pathway for sweet sensation: possible mechanisms and physiological relevance	7
The bile acid-sensitive ion channel (BASIC) mediates bile acid-dependent currents in bile duct epithelial cells	7
Impact of intracellular hemin on N-type inactivation of voltage-gated K+ channels	7
Regulation of CaV3.2 channels by the receptor for activated C kinase 1 (Rack-1)	7
Myostatin regulates the production of fibroblast growth factor 23 (FGF23) in UMR106 osteoblast–like cells	7
Tuft cell integration of luminal states and interaction modules in tissues	7
Ventrolateral periaqueductal gray matter integrative system of defense and antinociception	7
Metabolic instability vs fibre recruitment contribution to the $${\dot{V}O_2}$$ slow component in different exercise intensity domains	7
SOCE in the cardiomyocyte: the secret is in the chambers	7
Influence of layer separation on the determination of stomach smooth muscle properties	7
β-Adrenoceptor blockade prevents carotid body hyperactivity and elevated vascular sympathetic nerve density induced by chronic intermittent hypoxia	7
Lithium enhances exercise-induced glycogen breakdown and insulin-induced AKT activation to facilitate glucose uptake in rodent skeletal muscle	7
Carbonic anhydrase IX and hypoxia-inducible factor 1 attenuate cardiac dysfunction after myocardial infarction	7
Ion channelopathies to bridge molecular lesions, channel function, and clinical therapies	7
Understanding diabetes-induced cardiomyopathy from the perspective of renin angiotensin aldosterone system	7
Electrophysiological characterization of ectopic spontaneous discharge in axotomized and intact fibers upon nerve transection: a role in spontaneous pain?	7

Propagation of spontaneous electrical activity in the ex vivo human uterus	7
Cereblon: promise and challenges for combating human diseases	7
Neurogenic tachykinin mechanisms in experimental nephritis of rats	7
The (pro)renin receptor (ATP6ap2) facilitates receptor-mediated endocytosis and lysosomal function in the renal proximal tubule	7
The anion exchanger PAT-1 (Slc26a6) does not participate in oxalate or chloride transport by mouse large intestine	7
Chamber-specific regulation of atrial natriuretic peptide secretion in cardiac hypertrophy: atrial wall dynamics in the ANP secretion	7
Roles of glutamate and GABA of the Kölliker-Fuse nucleus in generating the cardiovascular chemoreflex	7
Stimulation of ORAI1 expression, store-operated Ca2+ entry, and osteogenic signaling by high glucose exposure of human aortic smooth muscle cells	7
Slow recovery from the inactivation of voltage-gated sodium channel Nav1.3 in mouse taste receptor cells	7
Increased β-adrenergic stimulation augments vascular smooth muscle cell calcification via PKA/CREB signalling	7
Flexible and multifaceted: the plasticity of renin-expressing cells	7