OOIR: Observatory of International Research

Papers

(The TQCC of Pflugers Archiv-European Journal of Physiology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Zebrafish cardiac repolarization does not functionally depend on the expression of the hERG1b-like transcript	59
Development of autonomic heart rate modulations during childhood and adolescence	55
Immune-mediated impairment of tonic immobility defensive behavior in an experimental model of colonic inflammation	48
Decoding influences of indoor temperature and light on neural activity: entropy analysis of electroencephalographic signals	43
Linking mitochondrial dynamics and fertility: promoting fertility by phoenixin through modulation of ovarian expression of GnRH receptor and mitochondrial dynamics proteins DRP-1 and Mfn-2	41
Piezo1, the new actor in cell volume regulation	40
Causality and scientific explanation of artificial intelligence systems in biomedicine	35
Endogenous ion channels expressed in human embryonic kidney (HEK-293) cells	33
Resting membrane state as an interplay of electrogenic transporters with various pumps	33
Combining different ion-selective channelrhodopsins to control water flux by light	32
Impact of aldosterone deficiency on the development of diuretic resistance in mice	30
Relevance of stromal interaction molecule 1 (STIM1) in experimental and human stroke	28
Evaluation of the relationship between intercostal muscle oxygenation measured by near-infrared spectroscopy and exercise capacity in group E COPD patients	28
Molecular determinants of HERG potassium channel blockade by domiphen bromide and benzethonium chloride	26
Blood transcriptomics mirror regulatory mechanisms during hibernation—a comparative analysis of the Djungarian hamster with other mammalian species	25
AFM-based nanoindentation indicates an impaired cortical stiffness in the AAV-PCSK9DY atherosclerosis mouse model	25
Is XPR1 mediating phosphate efflux?	24
Nobel Prize for physiology or medicine in 2024 for the discovery of microRNAs: small RNAs with fundamental roles in development and disease	24
XPR1: a regulator of cellular phosphate homeostasis rather than a Pi exporter	24
Effects of butyrate− on ruminal Ca2+ transport: evidence for the involvement of apically expressed TRPV3 and TRPV4 channels	23
Lipid metabolic reprogramming by hypoxia-inducible factor-1 in the hypoxic tumour microenvironment	21
FGF-23 protects cell function and viability in murine pancreatic islets challenged by glucolipotoxicity	21
Localization of natriuretic peptide receptors A, B, and C in healthy and diseased mouse kidneys	21
Creatine monohydrate supplementation and NOX impact skeletal muscle microvascular blood flow: a pilot study	21
Increased β-adrenergic stimulation augments vascular smooth muscle cell calcification via PKA/CREB signalling	20

A role for plasma membrane Ca2+ ATPases in regulation of cellular Ca2+ homeostasis by sphingosine kinase-1	20
Sodium retention in nephrotic syndrome is independent of the activation of the membrane-anchored serine protease prostasin (CAP1/PRSS8) and its enzymatic activity	19
Measured GFR in murine animal models: review on methods, techniques, and procedures	19
Colonic expression of calcium transporter TRPV6 is regulated by dietary sodium butyrate	17
Comprehensive overview of artificial intelligence in surgery: a systematic review and perspectives	17
Novel functions of the anion exchanger AE4 (SLC4A9)	17
The extracellular matrix protein fibronectin promotes metanephric kidney development	16
BK channels promote action potential repolarization in skeletal muscle but contribute little to myotonia	16
Mechanisms underlying spontaneous phasic contractions and sympathetic control of smooth muscle in the rat caudal epididymis	16
Obituary for Prof. Stephen (Ben) Walsh, Professor of Nephrology at University College London	16
Correction to: Nobel somatosensations and pain	16
Immune mediators in heart–lung communication	15
Functional characterization of acid-sensing ion channels in the cerebellum-originating medulloblastoma cell line DAOY and in cerebellar granule neurons	15
Sphingosine kinase 1 inhibition aggravates vascular smooth muscle cell calcification	15
Regulation of endothelial function by cigarette smoke and next-generation tobacco and nicotine products	15
Voltage-dependent CaV3.2 and CaV2.2 channels in nociceptive pathways	14
Identification of Dp140 and α1-syntrophin as novel molecular interactors of the neuronal CaV2.1 channel	14
Evaluation of skeletal muscle function in male rats with doxorubicin-induced myopathy following various exercise techniques: the significant role of glucose transporter 4	14
What can we learn about acid-base transporters in cancer from studying somatic mutations in their genes?	13
Controlled dietary phosphate loading in healthy young men elevates plasma phosphate and FGF23 levels	13
Neuroprotective actions of norepinephrine in neurological diseases	13
Effects of tDCS on glutamatergic pathways in epilepsy: neuroprotective and therapeutic potential	13
Basal release of 6-cyanodopamine from rat isolated vas deferens and its role on the tissue contractility	13
Cell surface ATP synthase-released H+ and ATP play key roles in cocoa butter intake-mediated regulation of gut immunity through releases of cytokines in rat	13
AMPK facilitates the hypoxic ventilatory response through non-adrenergic mechanisms at the brainstem	12
Harnessing retinal phagocytes to combat pathological neovascularization in ischemic retinopathies?	12
The role of Na+-coupled bicarbonate transporters (NCBT) in health and disease	12
The machinery of healthy vasodilatation: an overview	12
Obituary Peter H. Deetjen (1932–2024): Editor-in-Chief of Pflügers Archiv from 1970 to 1998	12
Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats	12
Alteration of Piezo1 signaling in type 2 diabetic mice: focus on endothelium and BKCa channel	12
Emerging connections between Piezo1 and BK channels in vascular smooth muscle cells	12
Effects of aconitine on the respiratory activity of brainstem-spinal cord preparations isolated from newborn rats	12
Renal water transport in health and disease	11
Vitamin C transporter SVCT1 serves a physiological role as a urate importer: functional analyses and in vivo investigations	11
Inconclusive evidence that breathing shapes pupil dynamics in humans: a systematic review	11
The lateral habenula regulates stress-related respiratory responses via the monoaminergic system	11
Commentary on “Failer et al. (2022) Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation” J Clin Invest 2022 (https://doi.org/10.1172/JCI	11
The role of non-coding RNAs in neuropathic pain	11
Peripheral arterial tone during active standing	11
Strength and muscle mass development after a resistance-training period at terrestrial and normobaric intermittent hypoxia	11
Optimization of an autaptic culture system for studying cholinergic synapses in sympathetic ganglia	10
Correction to: Differential frequency-dependent reflex summation of the aortic baroreceptor afferent input	10
Potential regulatory role of PGC-1α within the skeletal muscle during metabolic adaptations in response to high-fat diet feeding in animal models	10
Strengthening the basics: acids and bases influence vascular structure and function, tissue perfusion, blood pressure, and human cardiovascular disease	10
Correction to: Effect of salivary gland removal on taste preference in mice	10
GPD1L-A306del modifies sodium current in a family carrying the dysfunctional SCN5A-G1661R mutation associated with Brugada syndrome	10
Skeletal muscle proteins involved in fatty acid transport influence fatty acid oxidation rates observed during exercise	9
Recent advances in acid sensing by G protein coupled receptors	9
Two firing modes and well-resolved Na+, K+, and Ca2+ currents at the cell-microelectrode junction of spontaneously active rat chromaffin cell on MEAs	9

CFTR—a (novel) target in ARDS	9
Intermittent hypoxia training effectively protects against cognitive decline caused by acute hypoxia exposure	9
Biophysical mechanisms of myocardium sodium channelopathies	9
Insights into permeability control of the fenestrated endothelium of the jejunal microvasculature	9
The context-dependent role of the Na+/Ca2+-exchanger (NCX) in pancreatic stellate cell migration	9
Neuronal allodynic mechanisms of Slc7a5 (LAT1) in the spared nerve injury rodent model of neuropathic pain	9
Oligodendrocyte precursor cells: the multitaskers in the brain	9
“The great mixing machine”: multisensory integration and brain-breath coupling in the cerebral cortex	9
High-fat diet-induced mitochondrial dysfunction is associated with loss of protection from ischemic preconditioning in renal ischemia reperfusion	8
Unlocking the potential: unveiling tyrphostins with Michael-reactive cyanoacrylate motif as promising inhibitors of human 5-lipoxygenase	8
Acute and chronic effects of physical exercise on IgA and IgG levels and susceptibility to upper respiratory tract infections: a systematic review and meta-analysis	8
Determinants of hypokalemia following hypertonic sodium bicarbonate infusion	8
Uncovering the neural control of laryngeal activity and subglottic pressure in anaesthetized rats: insights from mesencephalic regions	8
Swimming and L-arginine loaded chitosan nanoparticles ameliorates aging‐induced neuron atrophy, autophagy marker LC3, GABA and BDNF-TrkB pathway in the spinal cord of rats	8
PKC regulates αKlotho gene expression in MDCK and NRK-52E cells	8
Metabolic characteristics of transmembrane prolyl 4-hydroxylase (P4H-TM) deficient mice	8
Hypoxia-inducible factor-driven glycolytic adaptations in host-microbe interactions	8
14–3-3 protein regulation of excitation–contraction coupling	8
Intracellular pH regulates the strength of the intrinsic inward rectification of Kir4.1/Kir5.1 channels	8
The role of GABA in modulation of taste signaling within the taste bud	7
Correction to: Dynamic expression of homeostatic ion channels in differentiated cortical astrocytes in vitro	7
Exposure to normobaric hypoxia shapes the acute inflammatory response in human whole blood cells in vivo	7
Diet-induced impairment of skeletal muscle and adipose tissue metabolic homeostasis and its prevention by probiotic administration	7
Proteolytic ENaC activation in health and disease—a complicated puzzle	7
Correction to: Two adjacent phosphorylation sites in the C-terminus of the channel’s α-subunit have opposing effects on epithelial sodium channel (ENaC) activity	7
The ex vivo perfused mouse adrenal gland—a new model to study aldosterone secretion	7
Phosphate intake, hyperphosphatemia, and kidney function	7
Intra- and inter-session reliability of electrical detection and pain thresholds of cutaneous and muscle primary afferents in the lower back of healthy individuals	7
The crucial decade that ion channels were proven to exist	7
Acid-sensing ion channels and downstream signalling in cancer cells: is there a mechanistic link?	7
Dopamine receptor D4 (DRD4) negatively regulates UCP1- and ATP-dependent thermogenesis in 3T3-L1 adipocytes and C2C12 muscle cells	7
Correction to: Persistent sodium currents in neurons: potential mechanisms and pharmacological blockers	7
Interleukin 17A infusion has no acute or long-term hypertensive action in conscious unrestrained male mice	7
Extended spectrum of Cav1.3 channelopathies	7
Aggressive migration in acidic pH of a glioblastoma cancer stem cell line in vitro is independent of ASIC and KCa3.1 ion channels, but involves phosphoinositide 3-kinase	7
Recent advances and current limitations of available technology to optically manipulate and observe cardiac electrophysiology	6
Adrenoceptor sub-type involvement in Ca2+ current stimulation by noradrenaline in human and rabbit atrial myocytes	6
Identification of a novel redox switch between metabolism and cardiac function using HyPer power	6
Excitation-secretion coupling in chromaffin cells of the adrenal gland: Where does calcium come from?	6
Connexin mRNA distribution in adult mouse kidneys	6
E-cigarette effects on vascular function in animals and humans	6
Angiotensin receptors and α1B-adrenergic receptors regulate native IK(ACh) and phosphorylation-deficient GIRK4 (S418A) channels through different PKC isoforms	6
Characterization and functional role of rapid- and slow-activating delayed rectifier K+ currents in atrioventricular node cells of guinea pigs	6
Cobalt chloride postconditioning as myoprotective therapy in cardiac ischemia–reperfusion	6
Lessons from a model: early glucagon dysfunction in type 2 diabetes	6
hPSC gene editing for cardiac disease therapy	6
Tissue chaperoning—the expanded functions of fetuin-A beyond inhibition of systemic calcification	6
Intracellular cAMP signaling-induced Ca2+ influx mediated by calcium homeostasis modulator 1 (CALHM1) in human odontoblasts	6
Role of glucocorticoid receptor mutations in hypertension and adrenal gland hyperplasia	6
Galectin-3 protects distal convoluted tubules in rhabdomyolysis-induced kidney injury	6
Does the composition of urinary extracellular vesicles reflect the abundance of renal Na+/phosphate transporters?	6
Cargo-specific effects of hypoxia on clathrin-mediated trafficking	6
Tuft cell integration of luminal states and interaction modules in tissues	6
No single place for space: neuronal representation of location beyond the hippocampus	6
25-Hydroxycholesterol modulates synaptic vesicle endocytosis at the mouse neuromuscular junction	6
Role of the endothelial reverse mode sodium-calcium exchanger in the dilation of the rat middle cerebral artery during hypoosmotic hyponatremia	6
Correction to: SGLT2 and cancer	6
Microbiota, mitochondria, and epigenetics in health and disease: converging pathways to solve the puzzle	6