European Journal of Clinical Pharmacology

Article	Citations
Association study identifies genetic determinants and non-genetic factors on steady-state plasma and therapeutic outcome of galantamine in mixed dementia	158
Understanding attitudes towards psychiatric medications: a comparative study of patients, healthcare professionals, and general population perspectives	73
Anticholinergic burden and cognitive performance: cross-sectional results from the ELSA-Brasil study	61
Might chronic spontaneous urticaria develop after SARS-CoV-2 vaccinations?	46
Oral Melatonin for Pain Relief During Venepuncture in Neonates– a Pilot Randomized Control Trial	41
How to make the best of NLRP3 inhibitors in patients with COVID-19?	37
A systematic literature review of economic evaluations of setmelanotide	36
Population pharmacokinetics and pharmacodynamics of meropenem in critically ill patients with renal impairment or on continuous renal replacement therapy	35
Signal detection between 5-alpha reductase inhibitors and the risk of suicidality and depression: an international pharmacovigilance analysis	32
Incidence and risk factors of drug-induced kidney injury in children: a systematic review and meta-analysis	32
A Study Of the effect of Sex on drug dosing, concentrations, and pharmacogenomics in the Montreal Heart Institute Hospital Cohort (SOS-PGx): methodology and research progress	30
Identification of novel signal of DRESS associated with antibiotics: a disproportionality analysis of the FDA adverse event reporting system (FAERS) database	29
Correction to: A real-world pharmacovigilance study of adverse events associated with esketamine: disproportionality analysis and detection of potential drug-drug interaction signals	29
A phase 1 study in healthy participants to characterize the safety and pharmacology of inclacumab, a fully human anti-P-selectin antibody, in development for treatment of sickle cell disease	29
Lowering cyclosporine trough concentration threshold effectively mitigates acute graft-versus-host disease in children with severe β-Thalassemia post hematopoietic stem cell transplantation	28
Usefulness of mirtazapine and SSRIs in late-life depression: post hoc analysis of the GUNDAM study	26
Beyond safety: adverse events and unanticipated advantages of SGLT2 inhibitors	25
The efficacy and safety of direct oral anticoagulants versus vitamin K antagonists in patients with left-sided bioprosthetic heart valves and atrial fibrillation: a systematic review and meta-analysis	25
Use of overactive bladder anticholinergic medications associated with falls leading to emergency department visits: results from the ADRED study	25
Effects of sodium-glucose cotransporter 2 inhibitors on renal risk factors in patients with abnormal glucose metabolism: a meta-analysis of randomized controlled trials	25
Comment on “Use of statins and risks of ovarian, uterine, and cervical diseases: a cohort study in the UK Biobank”	22
Challenges of pediatric pharmacotherapy: A narrative review of pharmacokinetics, pharmacodynamics, and pharmacogenetics	21
Clinical pharmacology—how it shapes the drug development journey	21
Dose selection for aztreonam-avibactam, including adjustments for renal impairment, for Phase IIa and Phase III evaluation	21
Assessment of body mass-related covariates for rifampicin pharmacokinetics in healthy Caucasian volunteers	21

Association of high risk of liver fibrosis in patients with serious outcomes of adverse drug reactions	21
Self-reported adherence to direct oral anticoagulants versus warfarin therapy in a specialized thrombosis service—a cross-sectional study of patients in a Canadian Health Region	20
Relationship between CYP2C8, UGT1A1, and ABCG2 gene polymorphisms and the exposure, efficacy, and toxicity of eltrombopag in the treatment of refractory aplastic anemia	20
Trimetazidine and allopurinol for the prevention of Contrast-associated acute kidney injury in elective percutaneous coronary intervention: a randomized controlled trial	19
Recommendations for the safe use of direct oral anticoagulants in patients with cirrhosis based on a systematic review of pharmacokinetic, pharmacodynamic and safety data	19
Response to comment on “The role of prescribed opioids in Norwegian overdose deaths in 2005–2021”	19
Patient involvement in pharmacovigilance: determinants and evolution of reporting from 2011 to 2020 in France	18
Retrospective review of intermittent and continuous infusion vancomycin for methicillin-resistant Staphylococcus aureus bacteremia	18
Ethnicity evaluation of ferric pyrophosphate citrate among Asian and Non-Asian populations: a population pharmacokinetics analysis	18
Challenging the young and shaping the growth of clinical pharmacology: 10 years of the EACPT Early Career Clinical Pharmacologists (ECCP) working group	18
Economic evaluation of antibody-drug conjugates (ADCs) in patients with breast cancer: systematic review	18
Clinical pharmacokinetics and pharmacodynamics of ivosidenib in Chinese patients with relapsed or refractory IDH1-mutated acute myeloid leukemia	18
Construction and temporal external validation of interpretable machine-learning models for predicting tigecycline-associated hypofibrinogenemia	18
Effectiveness and safety of concomitant use of direct oral anticoagulants and antiarrhythmic drugs: a systematic review of observational studies	18
Purine xanthine oxidase inhibitors are not conducive to the prognosis of chronic heart failure: a meta-analysis	18
Anticoagulants in adult extracorporeal membrane oxygenation: alternatives to standardized anticoagulation with unfractionated heparin	18
The contribution of genotype-guided selection of P2Y12 inhibitor on prognosis in ACS /CCS patients undergoing percutaneous coronary intervention: a retrospective cohort study	18
Effect of dapagliflozin on malignant ventricular arrhythmias in elderly after acute myocardial infarction: a propensity score-matched cohort study	18
Cost-effectiveness of abortive and preventative treatments in patients with migraine: a systematic review	17
Effect of timing of administration on lipid-lowering efficacy of statins-meta-analysis	17
Oral mannitol for bowel preparation: a dose-finding phase II study	17
Simulation of Imatinib Pharmacokinetics in pregnant women with chronic myeloid leukemia in the third trimester	16
Incidence of hospital contacts with acute kidney injury after initiation of second-generation antipsychotics in older adults: a Danish population-based cohort study	16
Disproportionality analysis from World Health Organization data on migraine-specific medications and cerebrovascular diseases	16
Impact of eGFR estimation methods on drug dosing in pediatric ICU: a study of serum creatinine vs. cystatin C	16
Rating scales to measure adverse effects of medications in people with intellectual disability: a scoping review	15
Dose reduction and discontinuation due to the combination of CDK4/6 inhibitors and endocrine drugs: a systematic review and meta-analysis	15
Activities of clinical pharmacologists across Europe: A survey by the European association of clinical pharmacology and therapeutics	15
Cost-effectiveness of sofosbuvir- ledipasvir for Hepatitis C treatment: a systematic review	15
Cardiovascular medications used for comorbid diseases in patients with atrial fibrillation. The JoFib study	14
Efficacy of tacrolimus versus cyclosporine after lung transplantation: an updated systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials	14
Analgesic potential of transdermal nicotine patch in surgery: a systematic review and meta-analysis of randomised placebo-controlled trials	14
ChatGPT for generating multiple-choice questions: comment	14
Correction to: The risk of congenital heart defects associated with corticosteroids use during the first trimester of pregnancy: a systematic review and meta‑analysis	14
Does aspirin have an effect on risk of death in patients with COVID-19? A meta-analysis	14
Correction to: Analgesic effect of oral paracetamol 1000 mg/ibuprofen 400 mg, paracetamol 1000 mg/codeine 60 mg, paracetamol 1000 mg/ibuprofen 400 mg/codeine 60 mg, or placebo on acute postoperative p	14
Posting of clinical trial results and other critical information from completed medicines trials on ClinicalTrials.gov	13
Correction to: Adherence to psychotropic medication in completed suicide in Sweden 2006–2013: a forensic-toxicological matched case-control study	13
Statin treatment for primary and secondary prevention in elderly patients—a cross-sectional study in Stockholm, Sweden	13
Exploring heterogeneities of cardiovascular efficacy and effectiveness of SGLT2 inhibitors in patients with type 2 diabetes: an umbrella review of evidence from randomized clinical trials versus real-	13
The beneficial use of nitric oxide during cardiopulmonary bypass on postoperative outcomes in children and adult patients: a systematic review and meta-analysis of 2897 patients	13
Mechanisms of landiolol-mediated positive inotropy in critical care settings	13
Evaluating the safety and effectiveness of tolvaptan in patients with heart failure and renal impairment: a systematic review and meta-analysis	13
Abuse, dependence and withdrawal associated with fentanyl and the role of its (designated) route of administration: an analysis of spontaneous reports from Europe	12
Proton pump inhibitor use: systematic review of global trends and practices	12
Effect of metoprolol exposure following myocardial infarction on future cardiovascular events: a Mendelian randomization study	12
Grade ≥ 3 hematologic adverse events of immunotherapy in advanced NSCLC patients: a systematic review and meta-analysis	12
Proton pump inhibitors and gastric or colorectal cancer: a real-world safety analysis in the global pharmacovigilance database	12
ChatGPT for generating multiple-choice questions: Evidence on the use of artificial intelligence in automatic item generation for a rational pharmacotherapy exam	12
Imatinib pharmacokinetics and creatine kinase levels in chronic myeloid leukemia patients: implications for therapeutic response and monitoring	12

Tramadol and the risk of bleeding complications in patients on oral anticoagulants: a pharmacovigilance study	12
A cocktail probe approach to evaluate the effect of hormones on the expression and activity of CYP enzymes in human hepatocytes with conditions simulating late stage of pregnancy	12
Voriconazole therapeutic drug monitoring including analysis of CYP2C19 phenotype in immunocompromised pediatric patients with invasive fungal infections	12
Assessment of severity and avoidability of adverse drug reactions in neonates: a reproducibility study of the Hartwig tool and LAAT	12
Spikevax booster and delayed urticaria: a Swiss signal with diagnostic uncertainties due to a high proportion of direct patient reports	11
Pharmacotherapy of Alzheimer’s disease: an overview of systematic reviews	11
Risk of gastric cancer among long-term proton pump inhibitor users: a population-based cohort study	11
From empirical caution to precision resumption: model-informed management of a binimetinib overdose in a frail elderly patient	11
Tool use isn’t enough—outcomes matter	11
No evidence of clinical efficacy of oxomemazine in cough, according to a systematic review	11
Risk factors for thrombocytopenia in patients receiving linezolid therapy: a systematic review and meta-analysis	11
Will artificial intelligence chatbots replace clinical pharmacologists? An exploratory study in clinical practice	11
GLP 1 receptor agonists and obesity-associated cancers: a disproportionality analysis in Vigibase®	11
Peripheral edema induced by isosorbide mononitrate in an elderly patient: A case study of dose-related risks and drug interactions	11
Guideline-directed heart failure pharmacotherapy and depression/anxiety: a scoping review of heart failure and related cardiovascular populations	11
Prescribed drugs and comorbidities as risk factors for Torsades de Pointes arrhythmia: a Swedish population-based cohort study	10
Nitrofurantoin for the treatment of uncomplicated urinary tract infection in female patients: the impact of dosing regimen, age, and renal function on drug exposure	10
Could carbamazepine-acetazolamide interaction lead to a severe hepatocellular liver injury? an interaction that needs to be uncovered	10
Estimated equipotent conversion ratios of morphine, sufentanil and fentanyl as continuous infusion in neonatal intensive care units: a pharmacoepidemiologic cohort study	10
A novel physiologically-based pharmacokinetic model to estimate reduced CYP3A4 activity in cancer patients utilizing the neutrophil-to-lymphocyte ratio as an inflammatory marker	10
Effects of renal impairment on the pharmacokinetics, safety, and tolerability of pudexacianinium (ASP5354) after IV administration: a mechanistic exploration	10
Understanding hemoglobin contribution to high-dose methotrexate disposition—population pharmacokinetics in pediatric patients with hematological malignancies	10
ChatGPT for generating multiple-choice questions: a reply	10
Early albumin infusion and mortality in ICU patients with HFpEF: a target trial emulation study	10
Effectiveness and safety of vonoprazan-based regimens compared with those of proton pump inhibitor (PPI)–based regimens as first-line agents for Helicobacter pylori: a meta-analysis of randomized clin	10
Correction to: Use of antibiotics in the early COVID‑19 pandemic in Poland, the Netherlands and Spain, from erraticism to (more) logic	10
Meta-analysis of the associations of IMPDH and UGT1A9 polymorphisms with rejection in kidney transplant recipients taking mycophenolic acid	9
Teaching rational prescribing in undergraduate medical education: a systematic search and review	9
Relating consequential falls to individual and combinations of prescription medication use in Swedish older adults	9
Delayed gastric emptying and antiseizure medication absorption: a potential pharmacokinetic consideration for GLP-1/GIP receptor agonists	9
Oxytocin treatment for core symptoms in children with autism spectrum disorder: a systematic review and meta-analysis	9
A standard dose of linezolid puts patients with hepatic impairment at risk of overexposure	9
Comment on “CYP2C19 genotyping and mavacamten: predicting outcomes in normal, intermediate and rapid metabolisers in obstructive hypertrophic cardiomyopathy”	9
Tacrolimus improved the pregnancy outcomes of patients with refractory recurrent spontaneous abortion and immune bias disorders: a randomized controlled trial	9
Analgesic effect of oral paracetamol 1000 mg/ibuprofen 400 mg, paracetamol 1000 mg/codeine 60 mg, paracetamol 1000 mg/ibuprofen 400 mg/codeine 60 mg, or placebo on acute postoperative pain: a single-d	9
Clinical and biochemical characteristics, and outcome in 33 patients with ceftriaxone-induced liver injury	9
Systematic review and first meta-analysis of the efficacy and safety of gemcitabine-cisplatin combined with paclitaxel in patients with advanced biliary tract cancer	9
Clozapine prescribing in treatment-resistant schizophrenia – an updated systematic literature review of barriers and facilitators among clinicians	9
Patterns of inappropriate prescribing and clinical characteristics in patients at admission to an acute care of the elderly unit	8
Population pharmacokinetics of bedaquiline: a systematic review	8
Therapeutic drug monitoring as an essential tool to ensure clozapine efficacy and prevent its toxicity in smokers: a case report	8
Coenzyme Q10 as a potential add-on treatment for patients suffering from painful diabetic neuropathy: results of a placebo-controlled randomized trial	8
Trends in use of sodium-glucose co-transporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) in Australia in the era of increased evidence of their cardiovascular benef	8
Dose-dependent efficacy and safety of Filgotinib in moderate to severe Crohn’s disease: a grade-assessed systematic review and meta-analysis of randomized controlled trials	8
Serum trough concentration threshold and risk factors of cefoperazone-induced coagulopathy in critically ill patients: A retrospective case-control study	8
Population plasma and urine pharmacokinetics and the probability of target attainment of fosfomycin in healthy male volunteers	8
Optimization of vitamin K antagonist treatment: Near patient monitoring versus standard of care a parallel group clinical trial in older patients with atrial fibrillation	8
The Scottish medicines in pregnancy programme: supporting the surveillance of medicines use during pregnancy and assessment of associated clinical outcomes	8
Facilitators and barriers to generic and biosimilar medications in the Middle East and North Africa: insights from physicians and pharmacists—a systematic review	8
Perception of clinical research among patients and healthy volunteers of clinical trials	8
Physicochemical compatibility of caffeine citrate and caffeine base injections with parenteral medications used in neonatal intensive care settings	8
A real-world pharmacovigilance study of adverse events associated with esketamine: disproportionality analysis and detection of potential drug-drug interaction signals	8
Pharmacological interventions for preventing atrial fibrillation after lung surgery: systematic review and meta-analysis	8
Effect of transporter gene polymorphisms and valproate co-medication on the steady-state disposition of lamotrigine and their effect on efficacy in adults with epilepsy	8
Comment on “Prescribing patterns of glucagon like peptide-1 receptor agonists in the Swedish capital region: a register-based cross-sectional study”	8
Efficacy and safety of nitazoxanide and escitalopram as adjuvant therapies in patients with rheumatoid arthritis: a randomized controlled study	8
Non-persistence to antihypertensive drug therapy in Lithuania	8
Does evidence from RCTs suggest: SGLT2 inhibitors could not reduce myocardial infarction and stroke?	8
Perception of pharmacological equivalence of generics or biosimilars in healthcare professionals in Vienna	8
Effect of propranolol on pharmacokinetics of clozapine in schizophrenic patients: a meta-analysis	8
Estimating the impact of label design on reducing the risk of medication errors by applying HEART in drug administration	8
A collaborative study of the impact of N-nitrosamines presence and ARB recall on ARB utilization – results from IQVIA™ Disease Analyzer Germany	8
Why we should not recommend or offer fluvoxamine to COVID-19 patients?	8
Circadian considerations in antimicrobials	8
The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS) study	8
Impact of histamine-2 antagonist shortage on the incidence of hypersensitivity reactions to paclitaxel: a reconsideration of premedication protocols in France (PACLIREACT Study)	8
Impact of CYP2D6*2, CYP2D6*35, rs5758550, and related haplotypes on risperidone clearance in vivo	7
Impact of tofogliflozin on hepatic outcomes: a systematic review	7
Effects of dapagliflozin and empagliflozin on 6-min walk distance in heart failure with preserved and reduced ejection fraction: A systematic review and meta-analysis of randomized controlled trials i	7
Comparison between clopidogrel and ticagrelor in CYP2C19 loss-of-function alleles coronary artery disease and stroke patients: a meta-analysis	7
Response commentary: the effect of colchicine on coagulation in patients with chronic coronary disease who use vitamin K antagonists	7
The safety and efficacy of bevacizumab in treatment of recurrent low-grade glioma: a systematic review and meta-analysis	7
Association between antidepressant use and gynecological cancer risk: a systematic review and meta-analysis	7
Characteristics of isoniazid-induced psychosis: a systematic review of case reports and case series	7
Pharmacogenetics of opioid medications for relief of labor pain and post-cesarean pain: a systematic review and meta-analysis	7
Hospitalisations related to benzodiazepine, Z-drug, and opioid treatment in Italy: a claim on the risks associated with inappropriate use	7
Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range	7
A meta-analysis and systematic review of the first Trop-2-targeting antibody–drug conjugate (sacituzumab govitecan) in treating metastatic breast cancer	7
Effectiveness of treatments for propranolol toxicity: a systematic review of current approaches and evidence	7
Pharmacokinetics of nirmatrelvir/ritonavir and the drug-drug interaction with calcineurin inhibitor in renal transplant recipients	7

Duplicate prescriptions in the emergency department: a retrospective cohort study	7
Relationship between elevated bilirubin levels and enhanced warfarin effects during biliary obstruction	7
Written drug promotion from pharmaceutical companies to general practitioners: adherence to regulations over two decades	7
Exploring potential biomarkers and constructing prediction models of osimertinib based on a retrospective study	7
Approaches for posaconazole therapeutic drug monitoring and their clinical benefits	7
High refill-adherence to adalimumab is associated with low disease activity in patients with inflammatory bowel disease	7
Inhalation therapies in COPD — adverse drug reactions impact on emergency department presentations	7
Efficacy and safety of nitazoxanide in treating SARS-CoV-2 infection: a systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trials	7
Comment on: “Genome-wide association study of direct oral anticoagulants and their relation to bleeding”	7
15th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT)	7
Author’s reply to the letter to the editor: “Effects of dapagliflozin and empagliflozin on 6‑min walk distance in heart failure with preserved and reduced ejection fraction: A systematic review and me	7
Predictive Role of Serotonin Receptor (5HTR2A) and Dopamine Receptor (DRD2) gene polymorphisms in risperidone-induced weight gain and hyperprolactinemia in patients with schizophrenia	7
Influence of metformin on hyperandrogenism in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized clinical trials	7
Optimisation of warfarin-dosing algorithms for Han Chinese patients with CYP2C9*13 variants	6
Influence of cigarette smoking on drugs’ metabolism and effects: a systematic review	6
Area under the curve of tacrolimus using microsampling devices: towards precision medicine in solid organ transplantation?	6
Imeglimin systematic review: a novel therapeutic approach for type 2 diabetes—unveiling benefits on β-cell function, insulin sensitivity, and potential long-term glycaemic control (HbA1c)	6
Efficacy of cannabis-based medicine in the treatment of Tourette syndrome: a systematic review and meta-analysis	6
Factors influencing methotrexate pharmacokinetics highlight the need for individualized dose adjustment: a systematic review	6
Risk of agranulocytosis with metamizole in comparison with alternative medications based on health records in Spain	6
Innovative applications of artificial intelligence technology in pharmacometrics	6
Validating the accuracy of mathematical model–based pharmacogenomics dose prediction with real-world data	6
Efficacy and safety of CGRP monoclonal antibodies for migraine prevention in episodic migraine; a network Meta-analysis	6
The effect of concomitant use of proton pump inhibitors with CDK 4/6 inhibitors on survival in metastatic breast cancer	6
Effects of oral antidiabetic agents on the renin–angiotensin–aldosterone system	6
Effects of active vitamin D analogs and calcimimetic agents on PTH and bone mineral biomarkers in hemodialysis patients with SHPT: a network meta-analysis	6
COVID-19 and pregnancy: A European study on pre- and post-infection medication use	6
ACD856, a novel positive allosteric modulator of Trk receptors, single ascending doses in healthy subjects: Safety and pharmacokinetics	6
Time-dependent association between omeprazole and esomeprazole and hospitalization due to hyponatremia	6
Era of surrogate endpoints and accelerated approvals: a comprehensive review on applicability, uncertainties, and challenges from regulatory, payer, and patient perspectives	6
Dose-dependent effect of lamotrigine on quetiapine serum concentration in patients using instant release tablets	6
Efficacy and safety of different pharmacological interventions in the treatment of tardive dyskinesia: a systematic review and network meta-analysis	6
Correction to: Potentially inappropriate medications and cognitive performance: cross‑sectional results from the ELSA–Brasil study	6
Applying pharmacokinetic/pharmacodynamic measurements for linezolid in critically ill patients: optimizing efficacy and reducing resistance occurrence	6
JAK inhibitors and risk of major cardiovascular events or venous thromboembolism: a self-controlled case series study	6
Letter to the editor: "Effects of dapagliflozin and empagliflozin on 6-min walk distance in heart failure with preserved and reduced ejection fraction: a systematic review and meta-analysis of randomi	6
Drug repositioning in the COVID-19 pandemic: fundamentals, synthetic routes, and overview of clinical studies	6
Impact of trough abiraterone level on adverse events in patients with prostate cancer treated with abiraterone acetate	6
Real-world safety and effectiveness of pirfenidone and nintedanib in the treatment of idiopathic pulmonary fibrosis: a systematic review and meta-analysis	6
Trends in ADR reporting’ and the missing context: COVID-19, LMICs, and sociodemographic blind spots	6
Effect of digoxin on all-cause and cardiovascular mortality in patients with atrial fibrillation with and without heart failure: an umbrella review of systematic reviews and 12 meta-analyses	6
Effects of mirabegron on brown adipose tissue and metabolism in humans: A systematic review and meta-analysis	6