European Journal of Clinical Pharmacology

Article	Citations
How to make the best of NLRP3 inhibitors in patients with COVID-19?	102
Might chronic spontaneous urticaria develop after SARS-CoV-2 vaccinations?	36
A Study Of the effect of Sex on drug dosing, concentrations, and pharmacogenomics in the Montreal Heart Institute Hospital Cohort (SOS-PGx): methodology and research progress	35
Association study identifies genetic determinants and non-genetic factors on steady-state plasma and therapeutic outcome of galantamine in mixed dementia	34
Medication adherence among persons with coronary heart disease and associations with blood pressure and low-density-lipoprotein-cholesterol	34
Use of overactive bladder anticholinergic medications associated with falls leading to emergency department visits: results from the ADRED study	32
Understanding attitudes towards psychiatric medications: a comparative study of patients, healthcare professionals, and general population perspectives	28
Signal detection between 5-alpha reductase inhibitors and the risk of suicidality and depression: an international pharmacovigilance analysis	27
A phase 1 study in healthy participants to characterize the safety and pharmacology of inclacumab, a fully human anti-P-selectin antibody, in development for treatment of sickle cell disease	26
Incidence and risk factors of drug-induced kidney injury in children: a systematic review and meta-analysis	26
Anticholinergic burden and cognitive performance: cross-sectional results from the ELSA-Brasil study	25
Usefulness of mirtazapine and SSRIs in late-life depression: post hoc analysis of the GUNDAM study	23
Comment on “Use of statins and risks of ovarian, uterine, and cervical diseases: a cohort study in the UK Biobank”	22
The efficacy and safety of direct oral anticoagulants versus vitamin K antagonists in patients with left-sided bioprosthetic heart valves and atrial fibrillation: a systematic review and meta-analysis	22
Assessment of body mass-related covariates for rifampicin pharmacokinetics in healthy Caucasian volunteers	22
Recommendations for the safe use of direct oral anticoagulants in patients with cirrhosis based on a systematic review of pharmacokinetic, pharmacodynamic and safety data	21
Clinical pharmacology—how it shapes the drug development journey	20
Pharmacokinetics of mycophenolic acid and external evaluation of two limited sampling strategies of drug exposure in patients with juvenile systematic lupus erythematosus	19
Relationship between CYP2C8, UGT1A1, and ABCG2 gene polymorphisms and the exposure, efficacy, and toxicity of eltrombopag in the treatment of refractory aplastic anemia	18
Dose selection for aztreonam-avibactam, including adjustments for renal impairment, for Phase IIa and Phase III evaluation	18
Prevalence, contributory factors and severity of medication errors associated with direct-acting oral anticoagulants in adult patients: a systematic review and meta-analysis	18
Self-reported adherence to direct oral anticoagulants versus warfarin therapy in a specialized thrombosis service—a cross-sectional study of patients in a Canadian Health Region	18
Effects of sodium-glucose cotransporter 2 inhibitors on renal risk factors in patients with abnormal glucose metabolism: a meta-analysis of randomized controlled trials	18
Challenges of pediatric pharmacotherapy: A narrative review of pharmacokinetics, pharmacodynamics, and pharmacogenetics	18
Clinical pharmacokinetics and pharmacodynamics of ivosidenib in Chinese patients with relapsed or refractory IDH1-mutated acute myeloid leukemia	17

Oral mannitol for bowel preparation: a dose-finding phase II study	17
Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans	17
Incidence of hospital contacts with acute kidney injury after initiation of second-generation antipsychotics in older adults: a Danish population-based cohort study	17
Retrospective review of intermittent and continuous infusion vancomycin for methicillin-resistant Staphylococcus aureus bacteremia	17
The contribution of genotype-guided selection of P2Y12 inhibitor on prognosis in ACS /CCS patients undergoing percutaneous coronary intervention: a retrospective cohort study	17
Purine xanthine oxidase inhibitors are not conducive to the prognosis of chronic heart failure: a meta-analysis	17
Dose reduction and discontinuation due to the combination of CDK4/6 inhibitors and endocrine drugs: a systematic review and meta-analysis	17
Disproportionality analysis from World Health Organization data on migraine-specific medications and cerebrovascular diseases	16
Effect of dapagliflozin on malignant ventricular arrhythmias in elderly after acute myocardial infarction: a propensity score-matched cohort study	16
Patient involvement in pharmacovigilance: determinants and evolution of reporting from 2011 to 2020 in France	16
Effect of timing of administration on lipid-lowering efficacy of statins-meta-analysis	16
Cost-effectiveness of abortive and preventative treatments in patients with migraine: a systematic review	16
Effectiveness and safety of concomitant use of direct oral anticoagulants and antiarrhythmic drugs: a systematic review of observational studies	16
Anticoagulants in adult extracorporeal membrane oxygenation: alternatives to standardized anticoagulation with unfractionated heparin	16
Ethnicity evaluation of ferric pyrophosphate citrate among Asian and Non-Asian populations: a population pharmacokinetics analysis	16
Effect of GLP-1R rs2254336 and rs3765467 polymorphisms on gastrointestinal adverse reactions in type 2 diabetes patients treated with liraglutide	16
Evaluating the safety and effectiveness of tolvaptan in patients with heart failure and renal impairment: a systematic review and meta-analysis	15
Cardiovascular medications used for comorbid diseases in patients with atrial fibrillation. The JoFib study	15
ChatGPT for generating multiple-choice questions: comment	15
Rating scales to measure adverse effects of medications in people with intellectual disability: a scoping review	15
Risk assessment tools for QT prolonging pharmacotherapy in older adults: a systematic review	15
Correction to: The risk of congenital heart defects associated with corticosteroids use during the first trimester of pregnancy: a systematic review and meta‑analysis	15
Mechanisms of landiolol-mediated positive inotropy in critical care settings	14
Activities of clinical pharmacologists across Europe: A survey by the European association of clinical pharmacology and therapeutics	14
Posting of clinical trial results and other critical information from completed medicines trials on ClinicalTrials.gov	14
Exploring heterogeneities of cardiovascular efficacy and effectiveness of SGLT2 inhibitors in patients with type 2 diabetes: an umbrella review of evidence from randomized clinical trials versus real-	14
Does aspirin have an effect on risk of death in patients with COVID-19? A meta-analysis	14
Systemic quinolones and risk of retinal detachment III: a nested case–control study using a US electronic health records database	14
Correction to: Analgesic effect of oral paracetamol 1000 mg/ibuprofen 400 mg, paracetamol 1000 mg/codeine 60 mg, paracetamol 1000 mg/ibuprofen 400 mg/codeine 60 mg, or placebo on acute postoperative p	14
Statin treatment for primary and secondary prevention in elderly patients—a cross-sectional study in Stockholm, Sweden	13
Efficacy of tacrolimus versus cyclosporine after lung transplantation: an updated systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials	13
The beneficial use of nitric oxide during cardiopulmonary bypass on postoperative outcomes in children and adult patients: a systematic review and meta-analysis of 2897 patients	13
Analgesic potential of transdermal nicotine patch in surgery: a systematic review and meta-analysis of randomised placebo-controlled trials	13
ChatGPT for generating multiple-choice questions: Evidence on the use of artificial intelligence in automatic item generation for a rational pharmacotherapy exam	13
Grade ≥ 3 hematologic adverse events of immunotherapy in advanced NSCLC patients: a systematic review and meta-analysis	12
A cocktail probe approach to evaluate the effect of hormones on the expression and activity of CYP enzymes in human hepatocytes with conditions simulating late stage of pregnancy	12
Proton pump inhibitor use: systematic review of global trends and practices	12
Abuse, dependence and withdrawal associated with fentanyl and the role of its (designated) route of administration: an analysis of spontaneous reports from Europe	12
Effect of metoprolol exposure following myocardial infarction on future cardiovascular events: a Mendelian randomization study	12
Voriconazole therapeutic drug monitoring including analysis of CYP2C19 phenotype in immunocompromised pediatric patients with invasive fungal infections	12
No evidence of clinical efficacy of oxomemazine in cough, according to a systematic review	11
Safety profile of COVID-19 drugs in a real clinical setting	11
Nitrofurantoin for the treatment of uncomplicated urinary tract infection in female patients: the impact of dosing regimen, age, and renal function on drug exposure	11
Effectiveness and safety of vonoprazan-based regimens compared with those of proton pump inhibitor (PPI)–based regimens as first-line agents for Helicobacter pylori: a meta-analysis of randomized clin	11
Tramadol and the risk of bleeding complications in patients on oral anticoagulants: a pharmacovigilance study	11
GLP 1 receptor agonists and obesity-associated cancers: a disproportionality analysis in Vigibase®	11
Peripheral edema induced by isosorbide mononitrate in an elderly patient: A case study of dose-related risks and drug interactions	11
Risk factors for thrombocytopenia in patients receiving linezolid therapy: a systematic review and meta-analysis	11
Spikevax booster and delayed urticaria: a Swiss signal with diagnostic uncertainties due to a high proportion of direct patient reports	11
Imatinib pharmacokinetics and creatine kinase levels in chronic myeloid leukemia patients: implications for therapeutic response and monitoring	11

Evaluation of pharmacogenomics and hepatic nuclear imaging–related covariates by population pharmacokinetic models of irinotecan and its metabolites	11
Risk of gastric cancer among long-term proton pump inhibitor users: a population-based cohort study	11
Pharmacotherapy of Alzheimer’s disease: an overview of systematic reviews	11
Severe CNS depression with duloxetine, ciprofloxacin and CYP2D6 deficiency—role and recognition of drug-drug-gene interactions	10
Will artificial intelligence chatbots replace clinical pharmacologists? An exploratory study in clinical practice	10
A novel physiologically-based pharmacokinetic model to estimate reduced CYP3A4 activity in cancer patients utilizing the neutrophil-to-lymphocyte ratio as an inflammatory marker	10
Perception of pharmacological equivalence of generics or biosimilars in healthcare professionals in Vienna	10
Understanding hemoglobin contribution to high-dose methotrexate disposition—population pharmacokinetics in pediatric patients with hematological malignancies	10
Teaching rational prescribing in undergraduate medical education: a systematic search and review	10
ChatGPT for generating multiple-choice questions: a reply	10
Meta-analysis of the associations of IMPDH and UGT1A9 polymorphisms with rejection in kidney transplant recipients taking mycophenolic acid	10
Estimated equipotent conversion ratios of morphine, sufentanil and fentanyl as continuous infusion in neonatal intensive care units: a pharmacoepidemiologic cohort study	10
The effect of potent CYP2D6 inhibition on the pharmacokinetics and safety of deutetrabenazine in healthy volunteers	10
Facilitators and barriers to generic and biosimilar medications in the Middle East and North Africa: insights from physicians and pharmacists—a systematic review	10
A standard dose of linezolid puts patients with hepatic impairment at risk of overexposure	10
Patterns of inappropriate prescribing and clinical characteristics in patients at admission to an acute care of the elderly unit	10
Assessment of severity and avoidability of adverse drug reactions in neonates: a reproducibility study of the Hartwig tool and LAAT	10
Correction to: Use of antibiotics in the early COVID‑19 pandemic in Poland, the Netherlands and Spain, from erraticism to (more) logic	10
Could carbamazepine-acetazolamide interaction lead to a severe hepatocellular liver injury? an interaction that needs to be uncovered	10
Physiologically based pharmacokinetic model predictions of natural product-drug interactions between goldenseal, berberine, imatinib and bosutinib	10
Analgesic effect of oral paracetamol 1000 mg/ibuprofen 400 mg, paracetamol 1000 mg/codeine 60 mg, paracetamol 1000 mg/ibuprofen 400 mg/codeine 60 mg, or placebo on acute postoperative pain: a single-d	10
The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS) study	9
Population pharmacokinetics of bedaquiline: a systematic review	9
Clinical and biochemical characteristics, and outcome in 33 patients with ceftriaxone-induced liver injury	9
Oxytocin treatment for core symptoms in children with autism spectrum disorder: a systematic review and meta-analysis	9
Selective serotonin reuptake inhibitors use and the risk of hepatocellular carcinoma: a systematic review and dose–response analysis of cohort studies with one million participants	9
Non-persistence to antihypertensive drug therapy in Lithuania	9
Effect of propranolol on pharmacokinetics of clozapine in schizophrenic patients: a meta-analysis	9
Serum trough concentration threshold and risk factors of cefoperazone-induced coagulopathy in critically ill patients: A retrospective case-control study	9
Acid suppressant use in association with incidence and severe outcomes of COVID-19: a systematic review and meta-analysis	9
Tacrolimus improved the pregnancy outcomes of patients with refractory recurrent spontaneous abortion and immune bias disorders: a randomized controlled trial	9
Perception of clinical research among patients and healthy volunteers of clinical trials	9
Impact of histamine-2 antagonist shortage on the incidence of hypersensitivity reactions to paclitaxel: a reconsideration of premedication protocols in France (PACLIREACT Study)	9
Pharmacological interventions for preventing atrial fibrillation after lung surgery: systematic review and meta-analysis	9
Physicochemical compatibility of caffeine citrate and caffeine base injections with parenteral medications used in neonatal intensive care settings	9
Incremental net benefit of lipid-lowering therapy with PCSK9 inhibitors: a systematic review and meta-analysis of cost-utility studies	9
Does evidence from RCTs suggest: SGLT2 inhibitors could not reduce myocardial infarction and stroke?	9
Population plasma and urine pharmacokinetics and the probability of target attainment of fosfomycin in healthy male volunteers	9
Optimization of vitamin K antagonist treatment: Near patient monitoring versus standard of care a parallel group clinical trial in older patients with atrial fibrillation	9
Pharmacogenetics of opioid medications for relief of labor pain and post-cesarean pain: a systematic review and meta-analysis	8
A collaborative study of the impact of N-nitrosamines presence and ARB recall on ARB utilization – results from IQVIA™ Disease Analyzer Germany	8
Impact of CYP2D6*2, CYP2D6*35, rs5758550, and related haplotypes on risperidone clearance in vivo	8
Influence of metformin on hyperandrogenism in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized clinical trials	8
A meta-analysis and systematic review of the first Trop-2-targeting antibody–drug conjugate (sacituzumab govitecan) in treating metastatic breast cancer	8
Estimating the impact of label design on reducing the risk of medication errors by applying HEART in drug administration	8
Why we should not recommend or offer fluvoxamine to COVID-19 patients?	8
High refill-adherence to adalimumab is associated with low disease activity in patients with inflammatory bowel disease	8
Coenzyme Q10 as a potential add-on treatment for patients suffering from painful diabetic neuropathy: results of a placebo-controlled randomized trial	8
Characteristics of isoniazid-induced psychosis: a systematic review of case reports and case series	8
Effects of dapagliflozin and empagliflozin on 6-min walk distance in heart failure with preserved and reduced ejection fraction: A systematic review and meta-analysis of randomized controlled trials i	8
Trends in use of sodium-glucose co-transporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) in Australia in the era of increased evidence of their cardiovascular benef	8
Efficacy and safety of nitazoxanide in treating SARS-CoV-2 infection: a systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trials	8
Hospitalisations related to benzodiazepine, Z-drug, and opioid treatment in Italy: a claim on the risks associated with inappropriate use	8
Impact of tofogliflozin on hepatic outcomes: a systematic review	8
Comparison between clopidogrel and ticagrelor in CYP2C19 loss-of-function alleles coronary artery disease and stroke patients: a meta-analysis	8
Therapeutic drug monitoring as an essential tool to ensure clozapine efficacy and prevent its toxicity in smokers: a case report	8
Assessing the binding interaction of polystyrene sulfonate with amitriptyline in healthy volunteers: a cross-over design — The BIND study	8
Relationship between elevated bilirubin levels and enhanced warfarin effects during biliary obstruction	7
Pharmacokinetics of nirmatrelvir/ritonavir and the drug-drug interaction with calcineurin inhibitor in renal transplant recipients	7
Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range	7
Author’s reply to the letter to the editor: “Effects of dapagliflozin and empagliflozin on 6‑min walk distance in heart failure with preserved and reduced ejection fraction: A systematic review and me	7
The effect of concomitant use of proton pump inhibitors with CDK 4/6 inhibitors on survival in metastatic breast cancer	7
Man vs. machine: comparison of pharmacogenetic expert counselling with a clinical medication support system in a study with 200 genotyped patients	7
Applying pharmacokinetic/pharmacodynamic measurements for linezolid in critically ill patients: optimizing efficacy and reducing resistance occurrence	7
ACD856, a novel positive allosteric modulator of Trk receptors, single ascending doses in healthy subjects: Safety and pharmacokinetics	7
The effect of preoperative statin treatment on acute kidney injury in elderly patients undergoing valve replacement surgery	7
Duplicate prescriptions in the emergency department: a retrospective cohort study	7
Inhalation therapies in COPD — adverse drug reactions impact on emergency department presentations	7
15th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT)	7
Predictive Role of Serotonin Receptor (5HTR2A) and Dopamine Receptor (DRD2) gene polymorphisms in risperidone-induced weight gain and hyperprolactinemia in patients with schizophrenia	7
Association between antidepressant use and gynecological cancer risk: a systematic review and meta-analysis	7
Influence of cigarette smoking on drugs’ metabolism and effects: a systematic review	7
Real-world safety and effectiveness of pirfenidone and nintedanib in the treatment of idiopathic pulmonary fibrosis: a systematic review and meta-analysis	7
JAK inhibitors and risk of major cardiovascular events or venous thromboembolism: a self-controlled case series study	7
Evaluation of pharmacological interventions in the management of adenomyosis: a systematic review	7
Impact of trough abiraterone level on adverse events in patients with prostate cancer treated with abiraterone acetate	7
Optimisation of warfarin-dosing algorithms for Han Chinese patients with CYP2C9*13 variants	7
Approaches for posaconazole therapeutic drug monitoring and their clinical benefits	7
Effects of oral antidiabetic agents on the renin–angiotensin–aldosterone system	7
External evaluation of published population pharmacokinetic models of polymyxin B	7

Era of surrogate endpoints and accelerated approvals: a comprehensive review on applicability, uncertainties, and challenges from regulatory, payer, and patient perspectives	7
Effects of mirabegron on brown adipose tissue and metabolism in humans: A systematic review and meta-analysis	7
A view of response and resistance to atomoxetine treatment in children with ADHD: effects of CYP2C19 polymorphisms and BDNF levels	6
Validating the accuracy of mathematical model–based pharmacogenomics dose prediction with real-world data	6
Risk of agranulocytosis with metamizole in comparison with alternative medications based on health records in Spain	6
The safety and efficacy of bevacizumab in treatment of recurrent low-grade glioma: a systematic review and meta-analysis	6
Effect of gene polymorphism on bleeding complications in Chinese Han patients taking warfarin	6
Dose-dependent effect of lamotrigine on quetiapine serum concentration in patients using instant release tablets	6
Factors predicting clinical and endoscopic remission with placebo therapy in East Asian patients with ulcerative colitis: a systematic review and meta-analysis	6
Correction to: Potentially inappropriate medications and cognitive performance: cross‑sectional results from the ELSA–Brasil study	6
Drug utilisation in neonatal units in England and Wales: a national cohort study	6
Efficacy of cannabis-based medicine in the treatment of Tourette syndrome: a systematic review and meta-analysis	6
Letter to the editor: "Effects of dapagliflozin and empagliflozin on 6-min walk distance in heart failure with preserved and reduced ejection fraction: a systematic review and meta-analysis of randomi	6
A genetic-based population PK/PD modeling of methadone in Chinese opiate dependence patients	6
Pharmacokinetics-pharmacodynamics of first-line antitubercular drugs: a comparative study in tuberculosis patients with and without concomitant diabetes mellitus	6
Time-dependent association between omeprazole and esomeprazole and hospitalization due to hyponatremia	6
Area under the curve of tacrolimus using microsampling devices: towards precision medicine in solid organ transplantation?	6
Factors influencing methotrexate pharmacokinetics highlight the need for individualized dose adjustment: a systematic review	6
Sodium-glucose cotransporter 2 inhibitors and contrast-induced nephropathy risk: a meta-analysis	6
Comment on: “Genome-wide association study of direct oral anticoagulants and their relation to bleeding”	6
Efficacy and safety of ramucirumab for gastric or gastro-esophageal junction adenocarcinoma: a systematic review and meta-analysis	6
Hypertension and Covid-19 vaccines: are there any differences between the different vaccines? A safety signal	6
Application of machine learning to predict tacrolimus exposure in liver and kidney transplant patients given the MeltDose formulation	6
Educational value of international and intercultural differences in prescribing: the international and interprofessional student-run clinic project	6