European Journal of Clinical Pharmacology

Article	Citations
Antiretroviral drug exposure in pregnancy and risk of congenital anomalies: a European case/non-case malformed study	82
Pharmacokinetics of polymyxin B in different populations: a systematic review	45
Comparative polymyxin B pharmacokinetics in critically ill patients with renal insufficiency and in continuous veno-venous hemodialysis	33
The effects of polymorphisms in CYP2C19, ATP-binding cassette transporter B1, and paraoxonase-1 on clopidogrel treatment of Uygur patients following percutaneous coronary intervention	32
Impact of combined propranolol and oxytocin on the process and outcomes of labor: a meta-analysis of randomized controlled trials	30
Association of the predicted free blood concentration of teicoplanin with the development of renal dysfunction	29
Outpatients prescribed with fluvoxamine around the time of COVID-19 diagnosis are not at a reduced risk of subsequent hospitalization and death compared to their non-prescribed peers: population-based	25
Creatine kinase elevation in chronic hepatitis B patients with telbivudine therapy: influence of telbivudine plasma concentration and single nucleotide polymorphisms of TK2, RRM2B, and NME4	25
Analysis of clinical characteristics and automatic monitoring of drug-induced arrhythmias in 167,546 inpatients	24
Association study identifies genetic determinants and non-genetic factors on steady-state plasma and therapeutic outcome of galantamine in mixed dementia	23
Long-acting B-2 agonists (LABA) or long-acting muscarinic antagonists (LAMA): which one may be the first option in group A COPD patients?	22
Usefulness of mirtazapine and SSRIs in late-life depression: post hoc analysis of the GUNDAM study	22
Dihydropyrimidine dehydrogenase phenotype in peripheral blood mononuclear cells is related to adverse events of fluoropyrimidine-therapy	21
Evidence-based medication adherence among seniors in the first year after heart failure hospitalisation and subsequent long-term outcomes: a restricted cubic spline analysis of adherence-outcome relat	21
Prediction of CYP2D6 poor metabolizers by measurements of solanidine and metabolites—a study in 839 patients with known CYP2D6 genotype	20
Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data	20
Use of overactive bladder anticholinergic medications associated with falls leading to emergency department visits: results from the ADRED study	19
Evaluation of drug interactions of saxagliptin with sildenafil in healthy volunteers	19
A critical review on approaches to generate and validate virtual population for physiologically based pharmacokinetic models: Methodologies, case studies and way forward	18
A clinical pharmacokinetic drug-drug interaction study between dextromethorphan and emvododstat, a potent anti-SARS-CoV-2 dihydroorotate dehydrogenase inhibitor	17
Effect of subcutaneous vs. intravenous tocilizumab in patients with severe COVID-19: a systematic review	16
Estimation of linezolid exposure in patients with hepatic impairment using machine learning based on a population pharmacokinetic model	16
Estimating the impact of label design on reducing the risk of medication errors by applying HEART in drug administration	16
Impact of histamine-2 antagonist shortage on the incidence of hypersensitivity reactions to paclitaxel: a reconsideration of premedication protocols in France (PACLIREACT Study)	16
Physicochemical compatibility of caffeine citrate and caffeine base injections with parenteral medications used in neonatal intensive care settings	16

Assessment of a systematic approach for implementing novel medications in clinical practice: an observational study with dapagliflozin	15
Comparison of ticagrelor and clopidogrel in anemic patients with acute coronary syndrome: efficacy and safety outcomes over one year	15
Effects of drugs on the oxygen dissociation curve—a scoping review	15
Trends in statin use for the primary prevention of atherosclerotic cardiovascular disease among US adults by demographic characteristics, 1999–2020	15
Drug–drug interaction of phenytoin sodium and methylprednisolone on voriconazole: a population pharmacokinetic model in children with thalassemia undergoing allogeneic hematopoietic stem cell transpla	15
A Study Of the effect of Sex on drug dosing, concentrations, and pharmacogenomics in the Montreal Heart Institute Hospital Cohort (SOS-PGx): methodology and research progress	15
The effect of concomitant beta-blocker use on survival in patients with metastatic renal cell carcinoma treated with a vascular endothelial growth factor receptor inhibitors in the first line	15
Differential inhibition of platelet function by cilostazol in combination with clopidogrel	15
Risk prediction models for adverse drug reactions and adverse drug events in older adults—a systematic review and meta-analysis	15
Prognostic effect of a vasopressin V2 receptor antagonist in acute congestive heart failure patients with hypoperfusion, the wet–cold pattern	15
Loncastuximab tesirine: an effective therapy for relapsed or refractory diffuse large B-cell lymphoma	14
Drug interaction alerts in older primary care patients, and related medically justified actions	14
A systematic review and meta-analysis of the efficacy of ketamine and esketamine on suicidal ideation in treatment-resistant depression	14
Prevalence and patient-rated relevance of complexity factors in medication regimens of community-dwelling patients with polypharmacy	14
Pharmacotherapeutic actions related to drug interaction alerts – a questionnaire study among Swedish hospital interns and residents in family medicine	14
Serum trough concentration threshold and risk factors of cefoperazone-induced coagulopathy in critically ill patients: A retrospective case-control study	14
Fast clearance of anti-TNFα agents unrelated to antidrug antibodies: a case report	14
Factors associated with long-term benzodiazepine and Z-drug use across the lifespan and 5-year temporal trajectories among incident users: a Swedish nationwide register-based study	14
Might chronic spontaneous urticaria develop after SARS-CoV-2 vaccinations?	13
How to make the best of NLRP3 inhibitors in patients with COVID-19?	13
Effect of propranolol on pharmacokinetics of clozapine in schizophrenic patients: a meta-analysis	13
Pharmacogenetics of warfarin dosing in Chinese adults with nonvalvular atrial fibrillation	13
Potential association between chia seeds use and low atazanavir trough concentrations in an HIV-infected patient	13
Comparison of ticagrelor and clopidogrel on platelet function and prognosis in unstable angina	13
Risk of hospital inpatient opioid overdose (RHINOO): a review of factors impacting naloxone administration in patients receiving opioids	12
Utility of endogenous 4β-hydroxycholesterol as a biomarker to assess cytochrome P 450 3A (CYP3A) activity: not quite ready for prime time	12
Evaluation of surrogate endpoints in phase III randomized control trials of advanced hepatocellular carcinoma treated with immune checkpoint inhibitors	12
Chemotherapy-induced neutropenia as a prognostic factor in patients with extensive-stage small cell lung cancer	12
Selective serotonin reuptake inhibitor (SSRI) antidepressants reduce COVID-19 infection: prospects for use	12
Population pharmacokinetics of bedaquiline: a systematic review	12
A rare side effect due to voriconazole: myasthenia gravis	12
Incidence and risk factors of drug-induced kidney injury in children: a systematic review and meta-analysis	12
Progress of PD-1/PD-L1 inhibitor combination therapy in immune treatment for HER2-positive tumors	12
A narrative review of the placebo effect: historical roots, current applications, and emerging insights	11
Trends in the use of oral anticoagulants, antiplatelets and statins in four European countries: a population-based study	11
Therapeutic drug monitoring in tuberculosis	11
Pharmacological interventions for preventing atrial fibrillation after lung surgery: systematic review and meta-analysis	11
How can polymyxin B be dosed based on current pharmacokinetic knowledge?	11
Fixed parameters in the population pharmacokinetic modeling of valproic acid might not be suitable: external validation in Chinese adults with epilepsy or after neurosurgery	11
Safety and efficacy of new oral anticoagulants compared to those of warfarin in AF patients with cancer: a meta-analysis of randomized clinical trials and observational studies	11
Within-subject pharmacokinetic variability has a strong influence on individual exposure ratios in bioequivalence studies, hence on drug formulation interchangeability	11
Comparative analysis of PIM criteria and drug labels in the elderly	10
Association between the use of hormonal contraceptives and risk of cholecystectomy in women of reproductive age	10
Causality assessment between reported fatal cerebral haemorrhage and suspected drugs: developing a new algorithm based on the analysis of the Japanese Adverse Event Report (JADER) database and literat	10
Association between the use of hormonal contraceptives and risk of gallstone disease	10
Population pharmacokinetics of valproic acid in adult Chinese patients with bipolar disorder	10
Trends and patterns in EU(7)-PIM prescribing to elderly patients in Germany	10
Cost effectiveness of antihypertensive drugs and treatment guidelines	10
Efficacy of high-dose atorvastatin or rosuvastatin loading in patients with acute coronary syndrome undergoing percutaneous coronary intervention: a meta-analysis of randomized controlled trials with	10
Retraction Note: Efficacy of vitamin C for the prevention and treatment of upper respiratory tract infection. A meta-analysis in children	10

A phase I study assessing the safety, tolerability, immunogenicity, and low-density lipoprotein cholesterol-lowering activity of immunotherapeutics targeting PCSK9	10
Comparing the clinical outcomes across different sodium/glucose cotransporter 2 (SGLT2) inhibitors in heart failure patients: a systematic review and network meta-analysis of randomized controlled tri	10
Circulating microRNA-30a-5p, microRNA-101-3p, microRNA-140-3p and microRNA-141-3p as potential biomarkers for dexmedetomidine response in pediatric patients	10
Severe acyclovir-induced encephalopathy in an elderly patient with herpes zoster	10
Lack of association between CYB5A gene rs1790834 polymorphism and the response to leflunomide in women with rheumatoid arthritis	9
Automated multi-dose dispensing in persons with and without Alzheimer’s disease—impacts on pharmacotherapy	9
Antihypertensive prescribing pattern, prescriber adherence to ISH 2020 guidelines, and implication of outpatient drug price on blood pressure control at selected hospitals in Southern Ethiopia	9
Anticholinergic burden and cognitive performance: cross-sectional results from the ELSA-Brasil study	9
Effects of antidepressant drug therapy with or without physical exercise on inflammatory biomarkers in major depressive disorder: a systematic review and meta-analysis of randomized controlled trials	9
Restrictions on the use of placebo in new COVID-19 vaccine trials	9
To establish a model for the prediction of initial standard and maintenance doses of warfarin for the Han Chinese population based on gene polymorphism: a multicenter study	9
Colorectal cancer chemotherapy: can sex-specific disparities impact on drug toxicities?	9
Simulations of topiramate dosage recommendations for poor compliance events	9
Adjuvant use of melatonin for relieving symptoms of painful diabetic neuropathy: results of a randomized, double-blinded, controlled trial	9
Loss of function polymorphisms in SLCO1B1 (c.521T>C, rs4149056) and ABCG2 (c.421C>A, rs2231142) genes are associated with adverse events of rosuvastatin: a case–control study	9
Selective serotonin reuptake inhibitors use and the risk of hepatocellular carcinoma: a systematic review and dose–response analysis of cohort studies with one million participants	9
Non-persistence to antihypertensive drug therapy in Lithuania	9
Aspirin for the prevention of hepatocellular carcinoma: an updated meta-analysis with particular focus on patients with chronic liver disease	8
Case report: cold medicines cause neuroleptic malignant-like syndrome in a patient with Parkinson’s disease	8
Treatment appropriateness of direct oral anticoagulants in patients with atrial fibrillation for stroke prevention: A real-world prospective study	8
Remdesivir treatment and clinical outcome in non-severe hospitalized COVID-19 patients: a propensity score matching multicenter Italian hospital experience	8
Effect of pregnane X receptor and cytochrome P450 oxidoreductase gene polymorphisms on trough concentrations of rivaroxaban and edoxaban in patients with nonvalvular atrial fibrillation	8
Evaluation of two European risk models for predicting medication harm in an Australian patient cohort	8
Cost-utility analysis of a structured medication review compared to usual care in Parkinson’s disease	8
Correction to: Prevalence and patient‑rated relevance of complexity factors in medication regimens of community dwelling patients with polypharmacy	8
Evolution of adverse drug reactions reporting systems: paper based to software based	8
A phase 1 study in healthy participants to characterize the safety and pharmacology of inclacumab, a fully human anti-P-selectin antibody, in development for treatment of sickle cell disease	8
Different interventions for preventing postoperative catheter-related bladder discomfort: a systematic review and meta-analysis	8
Development and application of Adverse drug reactions reports QUality Algorithm (AQUA-12) score: a single-centre quality improvement initiative	8
Ticagrelor versus clopidogrel in reducing inflammatory cell infiltration of thrombus aspirated in patients with ST-elevation myocardial infarction	8
Safety of pitolisant: a study in the WHO international pharmacovigilance database	8
Perception of clinical research among patients and healthy volunteers of clinical trials	8
Evaluation of hepatic CYP3A enzyme activity using endogenous markers in lung cancer patients treated with cisplatin, dexamethasone, and aprepitant	8
Comparing AGS Beers 2019, STOPP version 2, and EU(7)-PIM list in Portuguese older adults in primary health care	8
Efficacy of Aidi injection combined with chemotherapy, radiotherapy or chemoradiotherapy for unresectable esophageal cancer treatment: A meta-analysis and systematic review of 29 randomized controlled	8
The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS) study	8
Medication adherence among persons with coronary heart disease and associations with blood pressure and low-density-lipoprotein-cholesterol	8
Premature termination of clinical trials in Spain: reasons, characteristics, and opportunities to improve	8
Therapeutically dosed low molecular weight heparins in renal impairment: a nationwide survey	8
Population plasma and urine pharmacokinetics and the probability of target attainment of fosfomycin in healthy male volunteers	8
Waivers of informed consent in research with competent participants and the Declaration of Helsinki	7
Tinzaparin—a review of its molecular profile, pharmacology, special properties, and clinical uses	7
Characteristics and preventability of medication-related admissions for acute kidney injury and dehydration in elderly patients	7
Effect of posaconazole on the concentration of intravenous and oral cyclosporine in patients undergoing hematopoietic stem cell transplantation	7
Efficacy and safety of nitazoxanide in treating SARS-CoV-2 infection: a systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trials	7
Use of Japanese big data from electronic medical records to investigate risk factors and identify their high-risk combinations for linezolid-induced thrombocytopenia	7
Remimazolam versus propofol for sedation in gastrointestinal endoscopy and colonoscopy within elderly patients: a meta-analysis of randomized controlled trials	7
Olaparib-associated toxicity in cancer patients: a systematic review and meta-analysis	7
Comparing the effect of fluoxetine, escitalopram, and sertraline, on the level of BDNF and depression in preclinical and clinical studies: a systematic review	7
Effect of aspirin on incidence, recurrence, and mortality in prostate cancer patients: integrating evidence from randomized controlled trials and real-world studies	7
Response to: “Utility of endogenous 4β-hydroxycholesterol as a biomarker to assess cytochrome P 450 3A (CYP3A) activity: not quite ready for prime time”	7
Comment on “Use of statins and risks of ovarian, uterine, and cervical diseases: a cohort study in the UK Biobank”	7
Increased major bleeding incidence in atrial fibrillation patients with apixaban: a review of Japanese post-marketing surveillance studies of direct oral anticoagulants	7
Correction to: Empagliflozin and colchicine in patients with reduced left ventricular ejection fraction following ST-elevation myocardial infarction: a randomized, double-blinded, three-arm parallel-g	7
Potentially inappropriate medication use and mortality in patients with cognitive impairment	7
Trends in use of sodium-glucose co-transporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) in Australia in the era of increased evidence of their cardiovascular benef	7
Effects of dapagliflozin and empagliflozin on 6-min walk distance in heart failure with preserved and reduced ejection fraction: A systematic review and meta-analysis of randomized controlled trials i	7
Clinical comprehensive evaluation of direct oral anticoagulants for patients with atrial fibrillation in China	7
Reply to Lixin Du et al	7
Prevalence and bleeding risk associated with the concomitant use of direct oral anticoagulants and antiarrhythmic drugs in patients with atrial fibrillation, based on the French healthcare insurance d	7
Does evidence from RCTs suggest: SGLT2 inhibitors could not reduce myocardial infarction and stroke?	7
Clinical and cost-effectiveness analysis of carbapenems versus ciprofloxacin in the treatment of urinary tract infections due to extended spectrum β-lactamase-producing Enterobacterales	6
A collaborative study of the impact of N-nitrosamines presence and ARB recall on ARB utilization – results from IQVIA™ Disease Analyzer Germany	6
Impact of tofogliflozin on hepatic outcomes: a systematic review	6
The role of time interval elimination on pain control of preterm infants by sucrose administration	6
Does Ramadan fasting affect the therapeutic and clinical outcomes of warfarin?	6
Non-peer-reviewed data, effect measures, and meta-regression analysis on proton pump inhibitor use and COVID-19	6
Moderation of buprenorphine therapy for cocaine dependence efficacy by variation of the Prodynorphin gene	6
Pharmacokinetics of mycophenolic acid and external evaluation of two limited sampling strategies of drug exposure in patients with juvenile systematic lupus erythematosus	6
Recommendations for the safe use of direct oral anticoagulants in patients with cirrhosis based on a systematic review of pharmacokinetic, pharmacodynamic and safety data	6
The relationship between use of SGLT2is and incidence of respiratory and infectious diseases and site-specific fractures: a meta-analysis based on 32 large RCTs	6
A meta-analysis and systematic review based on perioperative management of elderly patients: is ciprofol an alternative to propofol?	6
Advances in the study of nebulized tranexamic acid for pulmonary hemorrhage	6
Assessment of body mass-related covariates for rifampicin pharmacokinetics in healthy Caucasian volunteers	6
Selective serotonin reuptake inhibitor use and the risk of hepatocellular carcinoma	6
Seronegative acute encephalitis following COVID-19 vaccines: a case series of an overlooked diagnosis with literature review	6
Population pharmacokinetics-pharmacodynamics of fondaparinux in dialysis-dependent chronic kidney disease patients undergoing chronic renal replacement therapy	6
Why we should not recommend or offer fluvoxamine to COVID-19 patients?	6
Characteristics of isoniazid-induced psychosis: a systematic review of case reports and case series	6
Sequencing strategies with ramucirumab and docetaxel following prior treatments for advanced non-small cell lung cancer: a multicenter retrospective cohort study	6

Clinical pharmacology—how it shapes the drug development journey	6
Risk of renal impairment in atypical antipsychotics: a systematic review and meta-analysis	6
Correction to: Acid suppressant use in association with incidence and severe outcomes of COVID‑19: a systematic review and meta‑analysis	6
Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans	6
Assessing the binding interaction of polystyrene sulfonate with amitriptyline in healthy volunteers: a cross-over design — The BIND study	6
Self-reported medication adherence and pharmacy refill adherence among persons with ischemic stroke: a cross-sectional study	6
Costs associated with adverse drug reactions in an older population admitted to hospital: a prospective cohort study	5
LABA/LAMA versus LABA/ICS fixed-dose combinations in the prevention of COPD exacerbations: a modeling analysis of literature aggregate data	5
Influence of metformin on hyperandrogenism in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized clinical trials	5
Improved adherence to statin treatment and differences in results between men and women after pictorial risk communication—a sub-study of the VIPVIZA RCT	5
Hospitalisations related to benzodiazepine, Z-drug, and opioid treatment in Italy: a claim on the risks associated with inappropriate use	5
Approaches for posaconazole therapeutic drug monitoring and their clinical benefits	5
Inhalation therapies in COPD — adverse drug reactions impact on emergency department presentations	5
Relationship between CYP2C8, UGT1A1, and ABCG2 gene polymorphisms and the exposure, efficacy, and toxicity of eltrombopag in the treatment of refractory aplastic anemia	5
Silymarin as a preventive or therapeutic measure for chemotherapy and radiotherapy-induced adverse reactions: a comprehensive review of preclinical and clinical data	5
Safety of COVID-19 vaccines in pregnancy: a VAERS based analysis	5
Neonatal outcomes after gamma-aminobutyric acid analog use during pregnancy: a meta-analysis of cohort studies	5
The efficacy and safety of direct oral anticoagulants versus vitamin K antagonists in patients with left-sided bioprosthetic heart valves and atrial fibrillation: a systematic review and meta-analysis	5
Long-term use of pharmacological treatment in Alzheimer’s disease: a retrospective cohort study in real-world clinical practice	5
Inconclusiveness of psychometric testing of medication adherence questionnaires	5
Therapeutic drug monitoring as an essential tool to ensure clozapine efficacy and prevent its toxicity in smokers: a case report	5
Missing PPI prescriptions while overprescribing?	5
Body composition is associated with tacrolimus pharmacokinetics in kidney transplant recipients	5
High refill-adherence to adalimumab is associated with low disease activity in patients with inflammatory bowel disease	5
Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range	5
COVID-19 and antiepileptic drugs: an approach to guide practices when nirmatrelvir/ritonavir is co-prescribed	5
Age of onset for increased dose-adjusted serum concentrations of antidepressants and association with sex and genotype: An observational study of 34,777 individuals	5
Self-reported adherence to direct oral anticoagulants versus warfarin therapy in a specialized thrombosis service—a cross-sectional study of patients in a Canadian Health Region	5
Population pharmacokinetics and dosage optimization of linezolid in Chinese older patients	5
Population pharmacokinetics of topiramate in Chinese children with epilepsy	5
Efficacy and safety of dabigatran and rivaroxaban in atrial fibrillation patients with impaired liver function: a multicenter retrospective cohort study	5
Estimation of cefepime, piperacillin, and tazobactam clearance with iohexol-based glomerular filtration rate in paediatric patients	5