OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacological Reviews is 22. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Seventy-Five Years of Interactions: The Department of Physiology and Pharmacology at Karolinska Institutet and Pharmacological Reviews	510
Table of Contents	314
Innovative therapeutics for renoprotection: Where we are	283
Neurobiological Mechanisms of Nicotine Reward and Aversion	186
The Role of G Protein–Coupled Receptors and Receptor Kinases in Pancreatic β-Cell Function and Diabetes	131
L-Type Calcium Channel Blockers: A Potential Novel Therapeutic Approach to Drug Dependence	115
Editorial Board	114
The Nitrogen Mustards	110
Review of Natural Language Processing in Pharmacology	109
Therapeutic advantage of combinatorial chimeric antigen receptor T cell and chemotherapies	108
The Myc Family and the Metastasis Suppressor NDRG1: Targeting Key Molecular Interactions with Innovative Therapeutics	108
Table of Contents	103
Table of Contents	93
Carbonic anhydrase inhibitors: “Old” drugs with new potential in unexpected areas	83
The endocannabinoidomes: Pharmacological redundancy and promiscuity, and multi-kingdom variety of sources and molecular targets	83
Metal-based Antibody, Nanobody, and Peptide Conjugates: Potential for Breast Cancer Therapy	79
Table of Contents	78
Pharmaceutical perspectives on oligonucleotide therapeutics and delivery systems	73
Elucidating the Interactome of G Protein-Coupled Receptors and Receptor Activity-Modifying Proteins	71
Optical Approaches for Investigating Neuromodulation and G Protein–Coupled Receptor Signaling	71
Innovation in cancer pharmacotherapy through integrative consideration of germline and tumor genomes	71
Pharmacological Modulation of the Crosstalk between Aberrant Janus Kinase Signaling and Epigenetic Modifiers of the Histone Deacetylase Family to Treat Cancer	71
International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily—Update 2023	70
Sex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review	64
Table of Contents	62

The Hippo pathway: Organ size control and beyond	58
Asthma therapeutics: Past, present, and future	58
Therapeutic Potential of Targeting Prokineticin Receptors in Diseases	58
Therapeutics in the Pipeline Targeting α-Synuclein for Parkinson's Disease	56
Molecular Tweezers: Supramolecular Hosts with Broad-Spectrum Biological Applications	54
Carbon Monoxide Signaling: Examining Its Engagement with Various Molecular Targets in the Context of Binding Affinity, Concentration, and Biologic Response	52
Roles of Individual Human Cytochrome P450 Enzymes in Drug Metabolism	50
G Protein-Coupled Receptor Pharmacology—Insights from Mass Spectrometry	49
Corrigendum to “International Union of Basic and Clinical Pharmacology. CXIX. Fundamental insights and clinical relevance regarding the carnitine palmitoyltransferase family of enzymes” [Pharmacologic	46
Sulfotransferase 2B1b, Sterol Sulfonation, and Disease	45
Nonhormonal Male Contraceptive Development—Strategies for Progress	44
Dopamine, Immunity, and Disease	43
Opportunities for Nitric Oxide in Potentiating Cancer Immunotherapy	43
Structure-Based Virtual Screening for Ligands of G Protein–Coupled Receptors: What Can Molecular Docking Do for You?	43
Targeting Persistent Changes in Neuroimmune and Epigenetic Signaling in Adolescent Drinking to Treat Alcohol Use Disorder in Adulthood	41
Neurobiology of the incubation of drug craving: An update	40
Editorial Board	40
Targeting Systemic Innate Immune Cells as a Therapeutic Avenue for Alzheimer Disease	37
Pharmacological Reviews’ 75th Year Anniversary: Past and Future—Editorial	36
Analgesic Potential of Terpenes Derived from Cannabis sativa	34
Extracellular Vesicle Heterogeneity and Its Impact for Regenerative Medicine Applications	34
Conotoxins Targeting Voltage-Gated Sodium Ion Channels	32
Effects of Medications on Heat Loss Capacity in Chronic Disease Patients: Health Implications Amidst Global Warming	31
Animal Behavior in Psychedelic Research	31
Heme-thiolate monooxygenase cytochrome P450 1B1, an old dog with many new tricks	31
Somatostatin: Linking Cognition and Alzheimer Disease to Therapeutic Targeting	30
Vitamin D and its analogs in immune system regulation	28
Post-Traumatic Epilepsy and Comorbidities: Advanced Models, Molecular Mechanisms, Biomarkers, and Novel Therapeutic Interventions	27
The Development of Cannabinoids as Therapeutic Agents in the United States	26
Immunology and Technology of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccines	26
Pharmacological strategies to bridge the gap between cancer and cardiovascular therapeutics	25
Time to Change: A Systems Pharmacology Approach to Disentangle Mechanisms of Drug-Induced Mitochondrial Toxicity	24
Table of Contents	24
Potassium Channels in Parkinson’s Disease: Potential Roles in Its Pathogenesis and Innovative Molecular Targets for Treatment	24
Table of Contents	22
International Union of Basic and Clinical Pharmacology. CXVIII. Update on the nomenclature for atypical chemokine receptors, including ACKR5	22
Table of Contents	22
Drugging dancing protein clouds: A close look at disorder-based drug design	22