OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacological Reviews is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Table of Contents	632
Table of Contents	426
Seventy-Five Years of Interactions: The Department of Physiology and Pharmacology at Karolinska Institutet and Pharmacological Reviews	268
Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies	257
Pharmacological Reviews’ 75th Year Anniversary: Past and Future—Editorial	219
Looking Under the Lamppost: The Search for New Cancer Targets in the Human Kinome	139
Correction to “Sex- and Gender-Based Pharmacological Response to Drugs”	129
Steatotic Liver Disease: Pathophysiology and Emerging Pharmacotherapies	123
Biochemistry, pharmacology, and in vivo function of arginases	113
International Union of Basic and Clinical Pharmacology. CXII: Adenosine Receptors: A Further Update	101
Prostaglandin E2 in the Tumor Microenvironment, a Convoluted Affair Mediated by EP Receptors 2 and 4	101
Editorial Board	95
Editorial Board	90
Editorial Board	85
Inhaled β2 Adrenergic Agonists and Other cAMP-Elevating Agents: Therapeutics for Alveolar Injury and Acute Respiratory Disease Syndrome?	84
Targeting Systemic Innate Immune Cells as a Therapeutic Avenue for Alzheimer Disease	83
Topically Applied Therapies for the Treatment of Skin Disease: Past, Present, and Future	82
Pharmacology of Hydrogen Sulfide and Its Donors in Cardiometabolic Diseases	82
Editorial Board	79
Editorial Board	77
Hope on the Horizon: Promising Therapies for Steatotic Liver Disease	75
A 25-Year Journey as Author and Associate Editor of Pharmacological Reviews—Editorial	72
A Chance to Grow and Excel as an Associate Editor of Pharmacological Reviews—Editorial	72
Modeling Pharmacokinetic Natural Product–Drug Interactions for Decision-Making: A NaPDI Center Recommended Approach	71
Understanding the Neural Mechanisms of General Anesthesia from Interaction with Sleep–Wake State: A Decade of Discovery	66

New Advances in the Pharmacology and Toxicology of Lithium: A Neurobiologically Oriented Overview	66
Analgesic Potential of Terpenes Derived from Cannabis sativa	60
The Role of G Protein–Coupled Receptors and Receptor Kinases in Pancreatic β-Cell Function and Diabetes	58
Organic anion transporting polypeptides: Pharmacology, toxicology, structure, and transport mechanisms	58
Extracellular Vesicle Heterogeneity and Its Impact for Regenerative Medicine Applications	58
Animal Models of Drug Relapse and Craving after Voluntary Abstinence: A Review	56
How to drug a cloud? Targeting intrinsically disordered proteins	55
The pharmacology of vitamin C	54
Pharmacologic treatments for gastroparesis	54
Endothelial Dysfunction in Atherosclerotic Cardiovascular Diseases and Beyond: From Mechanism to Pharmacotherapies	52
Multi- and polypharmacology of carbonic anhydrase inhibitors	51
Neurobiological Mechanisms of Nicotine Reward and Aversion	49
Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials	46
Review of Natural Language Processing in Pharmacology	45
Targeting the Liver with Nucleic Acid Therapeutics for the Treatment of Systemic Diseases of Liver Origin	45
Intestinal Lymphatic Biology, Drug Delivery, and Therapeutics: Current Status and Future Directions	42
The 75-Year Anniversary of the Department of Physiology and Pharmacology at Karolinska Institutet—Examples of Recent Accomplishments and Future Perspectives	41
Molecular Pathways Governing the Termination of Liver Regeneration	41
Editorial Board	40
A Commitment to Excellence from the New Editor	40
New Aspects of Diabetes Research and Therapeutic Development	39
L-Type Calcium Channel Blockers: A Potential Novel Therapeutic Approach to Drug Dependence	38
Editorial Board	38
International Union of Basic and Clinical Pharmacology. CXVII: Taste 2 receptors—Structures, functions, activators, and blockers	35
Animal Behavior in Psychedelic Research	35
Editorial Board	35
Pharmacological Reviews Announces Inaugural Social Media Ambassadors	32
Mass Spectrometry Approaches Empowering Neuropeptide Discovery and Therapeutics	32
Nonantimicrobial Actions of Macrolides: Overview and Perspectives for Future Development	31
Correction to “Oxycodone: A Current Perspective on Its Pharmacology, Abuse, and Pharmacotherapeutic Developments”	31
Ferroptosis and pathogenesis of neuritic plaques in Alzheimer disease	31
Conotoxins Targeting Voltage-Gated Sodium Ion Channels	30
Aiding and Abetting Anhedonia: Impact of Inflammation on the Brain and Pharmacological Implications	28
Ontogeny of Hepatic Transporters and Drug-Metabolizing Enzymes in Humans and in Nonclinical Species	28