OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacological Reviews is 20. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Seventy-Five Years of Interactions: The Department of Physiology and Pharmacology at Karolinska Institutet and Pharmacological Reviews	493
Table of Contents	305
Innovative therapeutics for renoprotection: Where we are	274
Neurobiological Mechanisms of Nicotine Reward and Aversion	178
The Role of G Protein–Coupled Receptors and Receptor Kinases in Pancreatic β-Cell Function and Diabetes	119
Editorial Board	112
Review of Natural Language Processing in Pharmacology	110
The Nitrogen Mustards	107
L-Type Calcium Channel Blockers: A Potential Novel Therapeutic Approach to Drug Dependence	104
The Myc Family and the Metastasis Suppressor NDRG1: Targeting Key Molecular Interactions with Innovative Therapeutics	103
Therapeutic advantage of combinatorial chimeric antigen receptor T cell and chemotherapies	101
Table of Contents	99
Table of Contents	92
The endocannabinoidomes: Pharmacological redundancy and promiscuity, and multi-kingdom variety of sources and molecular targets	83
Carbonic anhydrase inhibitors: “Old” drugs with new potential in unexpected areas	77
Table of Contents	75
International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily—Update 2023	74
Optical Approaches for Investigating Neuromodulation and G Protein–Coupled Receptor Signaling	71
Pharmaceutical perspectives on oligonucleotide therapeutics and delivery systems	68
Innovation in cancer pharmacotherapy through integrative consideration of germline and tumor genomes	68
Elucidating the Interactome of G Protein-Coupled Receptors and Receptor Activity-Modifying Proteins	65
Pharmacological Modulation of the Crosstalk between Aberrant Janus Kinase Signaling and Epigenetic Modifiers of the Histone Deacetylase Family to Treat Cancer	65
Sex Differences in Opioid and Psychostimulant Craving and Relapse: A Critical Review	64
Table of Contents	59
Asthma therapeutics: Past, present, and future	58

Molecular Tweezers: Supramolecular Hosts with Broad-Spectrum Biological Applications	57
The Hippo pathway: Organ size control and beyond	55
G Protein-Coupled Receptor Pharmacology—Insights from Mass Spectrometry	55
Therapeutic Potential of Targeting Prokineticin Receptors in Diseases	54
Roles of Individual Human Cytochrome P450 Enzymes in Drug Metabolism	52
Carbon Monoxide Signaling: Examining Its Engagement with Various Molecular Targets in the Context of Binding Affinity, Concentration, and Biologic Response	48
Therapeutics in the Pipeline Targeting α-Synuclein for Parkinson's Disease	47
Corrigendum to “International Union of Basic and Clinical Pharmacology. CXIX. Fundamental insights and clinical relevance regarding the carnitine palmitoyltransferase family of enzymes” [Pharmacologic	46
Nonhormonal Male Contraceptive Development—Strategies for Progress	44
Sulfotransferase 2B1b, Sterol Sulfonation, and Disease	44
Targeting Persistent Changes in Neuroimmune and Epigenetic Signaling in Adolescent Drinking to Treat Alcohol Use Disorder in Adulthood	44
Structure-Based Virtual Screening for Ligands of G Protein–Coupled Receptors: What Can Molecular Docking Do for You?	43
Opportunities for Nitric Oxide in Potentiating Cancer Immunotherapy	42
Dopamine, Immunity, and Disease	41
Neurobiology of the incubation of drug craving: An update	39
Editorial Board	39
Pharmacological Reviews’ 75th Year Anniversary: Past and Future—Editorial	37
Analgesic Potential of Terpenes Derived from Cannabis sativa	36
Targeting Systemic Innate Immune Cells as a Therapeutic Avenue for Alzheimer Disease	35
Heme-thiolate monooxygenase cytochrome P450 1B1, an old dog with many new tricks	32
Extracellular Vesicle Heterogeneity and Its Impact for Regenerative Medicine Applications	32
Conotoxins Targeting Voltage-Gated Sodium Ion Channels	31
Somatostatin: Linking Cognition and Alzheimer Disease to Therapeutic Targeting	29
Effects of Medications on Heat Loss Capacity in Chronic Disease Patients: Health Implications Amidst Global Warming	29
Vitamin D and its analogs in immune system regulation	27
Post-Traumatic Epilepsy and Comorbidities: Advanced Models, Molecular Mechanisms, Biomarkers, and Novel Therapeutic Interventions	26
Animal Behavior in Psychedelic Research	26
The Development of Cannabinoids as Therapeutic Agents in the United States	25
Immunology and Technology of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccines	25
Pharmacological strategies to bridge the gap between cancer and cardiovascular therapeutics	24
Table of Contents	23
International Union of Basic and Clinical Pharmacology. CXVIII. Update on the nomenclature for atypical chemokine receptors, including ACKR5	23
Time to Change: A Systems Pharmacology Approach to Disentangle Mechanisms of Drug-Induced Mitochondrial Toxicity	23
Potassium Channels in Parkinson’s Disease: Potential Roles in Its Pathogenesis and Innovative Molecular Targets for Treatment	21
α6-Containing GABAA Receptors: Functional Roles and Therapeutic Potentials	20
Anticoagulants: From chance discovery to structure-based design	20
Table of Contents	20
Drugging dancing protein clouds: A close look at disorder-based drug design	20
Table of Contents	20