OOIR: Observatory of International Research

Papers

(The H4-Index of Physiological Reviews is 57. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and Ca²⁺ signaling	589
Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries	366
Making a good egg: human oocyte health, aging, and in vitro development	338
SIRT7: the seventh key to unlocking the mystery of aging	323
Implications of the NADase CD38 in COVID pathophysiology	320
Systematic reviews for basic scientists: a different beast	259
A comprehensive review of the neuroscience of ingestion: the physiological control of eating: signals, neurons, and networks	256
Comparative physiological anthropogeny: exploring molecular underpinnings of distinctly human phenotypes	223
Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation	192
Contribution of adaptive immunity to human COPD and experimental models of emphysema	191
Sensing molecular carbon dioxide - a translational focus for respiratory disease	186
Sodium channelopathies of skeletal muscle and brain	175
Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms	166
The physiopathology of brain-derived neurotrophic factor	165
Rho GTPase signaling in cancer progression and dissemination	164
Neuronal glucose sensing mechanisms and circuits in the control of insulin and glucagon secretion	153
Immunotherapy for atherosclerosis	151
Understanding COVID-19 susceptibility and presentation based on its underlying physiology	137
Mitochondrial calcium exchange in physiology and disease	123
A primer on obesity-related cardiomyopathy	121
Complex physiology and clinical implications of time-restricted eating	117
Molecular dissection of the role of ACE2 in glucose homeostasis	117
Calcium-release channels: structure and function of IP₃ receptors and ryanodine receptors	114
The physiological control of eating: signals, neurons, and networks	108
The enteric nervous system	107

NETosis creates a link between diabetes and Long COVID	106
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs	105
Genome-wide association studies of cardiovascular disease	105
Lipids shape brain function through ion channel and receptor modulations: physiological mechanisms and clinical perspectives	103
How development sculpts hippocampal circuits and function	98
Redox signaling in the pancreas in health and disease	96
Determinants, maintenance, and function of organellar pH	95
The molecular athlete: exercise physiology from mechanisms to medals	94
Angiocrine and Pericrine Signaling: How Endothelial Cells and Pericytes Drive Cancer Progression and Therapy Resistance	92
Physiological roles of mammalian transmembrane adenylyl cyclase isoforms	91
The anterior chamber of the eye technology and its anatomical, optical, and immunological bases	89
Bioenergetics: the evolutionary basis of progressive kidney disease	88
Is Notch1 a neglected vascular mechanosensor?	82
The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes	81
NADPH oxidases: redox regulation of cell homeostasis and disease	80
Principles of odor coding in vertebrates and artificial chemosensory systems	79
In celebration of the 100th anniversary of Physiological Reviews	76
Physiologic mechanisms underlying polycystic kidney disease	73
Wonder of wonders, miracle of miracles: the unprecedented speed of COVID-19 science	69
Community-acquired bacterial coinfections and COVID-19	69
Evolutionarily conserved transcription factors as regulators of longevity and targets for geroprotection	68
Transforming the concept of connectivity: unveiling tunneling nanotube biology and their roles in brain development and neurodegeneration	67
Development of antifibrotic therapy for stricturing Crohn’s disease: lessons from randomized trials in other fibrotic diseases	63
Nanodomain cAMP signaling in cardiac pathophysiology: potential for developing targeted therapeutic interventions	62
The elusive cephalic phase insulin response: triggers, mechanisms, and functions	62
Fluid transport in the brain	61
Navigating the multifaceted intricacies of the Na⁺-Cl⁻ cotransporter, a highly regulated key effector in the control of hydromineral homeostasis	60
Frontiers in the physiology of male pattern androgenetic alopecia: Beyond the androgen horizon	59
Pathophysiology of syncope: current concepts and their development	59
Trained immunity: adaptation within innate immune mechanisms	58
Adhesion G protein-coupled receptors: structure, signaling, physiology, and pathophysiology	58
The physiological functions of human peroxisomes	57