OOIR: Observatory of International Research

Papers

(The median citation count of Physiological Reviews is 24. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Neuropathic Pain: From Mechanisms to Treatment	550
Diversity and Biology of Cancer-Associated Fibroblasts	533
Pregnancy and COVID-19	384
Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation	316
Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility	289
Regulation and metabolic functions of mTORC1 and mTORC2	269
Brain Lateralization: A Comparative Perspective	229
Physiology of the Endometrium and Regulation of Menstruation	213
Brain mechanisms of insomnia: new perspectives on causes and consequences	196
Molecular physiology of bile acid signaling in health, disease, and aging	196
Fluid transport in the brain	188
Behavioral and neurobiological mechanisms of pavlovian and instrumental extinction learning	172
Bone metastasis: mechanisms, therapies, and biomarkers	160
Exercise under heat stress: thermoregulation, hydration, performance implications, and mitigation strategies	159
Microenvironmental Determinants of Pancreatic Cancer	159
Cellular Circuits in the Brain and Their Modulation in Acute and Chronic Pain	158
SUMO: From Bench to Bedside	158
Developmental origins of metabolic diseases	156
Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications	153
Role of O-linked N-acetylglucosamine protein modification in cellular (patho)physiology	139
Physiology and Pathophysiology of Itch	128
Mitochondrial calcium exchange in physiology and disease	128
Revisiting the Functional Anatomy of the Human Brain: Toward a Meta-Networking Theory of Cerebral Functions	127
Sex determination, gonadal sex differentiation, and plasticity in vertebrate species	124
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs	120

The complexity of Alzheimer’s disease: an evolving puzzle	111
SARS-CoV-2 and COVID-19: From the Bench to the Bedside	108
Calcium-release channels: structure and function of IP₃ receptors and ryanodine receptors	97
Rho GTPase signaling in cancer progression and dissemination	96
The Female Response to Seminal Fluid	95
Cardiac Mechano-Electric Coupling: Acute Effects of Mechanical Stimulation on Heart Rate and Rhythm	93
Carotid body chemoreceptors: physiology, pathology, and implications for health and disease	92
The Urothelium: Life in a Liquid Environment	90
The osteocyte as a signaling cell	88
Cardiac transmembrane ion channels and action potentials: cellular physiology and arrhythmogenic behavior	86
Physiology and pathophysiology of human airway mucus	82
Glial Connexins and Pannexins in the Healthy and Diseased Brain	80
Mitochondrial quality control in health and in Parkinson’s disease	79
Mitochondria in health, disease, and aging	76
Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets	76
Human temperature regulation under heat stress in health, disease, and injury	76
From Ancient to Emerging Infections: The Odyssey of Viruses in the Male Genital Tract	75
The roles of calcium and ATP in the physiology and pathology of the exocrine pancreas	73
Nongenomic Actions of Thyroid Hormone: The Integrin Component	71
Ion Channels Controlling Circadian Rhythms in Suprachiasmatic Nucleus Excitability	67
Neuronal Circuits in Barrel Cortex for Whisker Sensory Perception	65
Are We Meeting the Promise of Endotypes and Precision Medicine in Asthma?	62
The physiological control of eating: signals, neurons, and networks	62
Role of the Epigenome in Heart Failure	58
Phosphate Transport in Epithelial and Nonepithelial Tissue	58
RNA-binding proteins balance brain function in health and disease	57
ER-phagy: mechanisms, regulation, and diseases connected to the lysosomal clearance of the endoplasmic reticulum	57
Sodium channelopathies of skeletal muscle and brain	56
Molecular Physiology and Pathophysiology of Bilirubin Handling by the Blood, Liver, Intestine, and Brain in the Newborn	55
Optophysiology: Illuminating cell physiology with optogenetics	54
Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training	53
The Renal Physiology of Pendrin-Positive Intercalated Cells	52
CGRP physiology, pharmacology, and therapeutic targets: migraine and beyond	52
Do hippocampal pyramidal cells respond to nonspatial stimuli?	51
G protein-coupled receptor-G protein interactions: a single-molecule perspective	50
Moving immune therapy forward targeting tme	48
The enteric nervous system	48
How development sculpts hippocampal circuits and function	48
Albumin uptake and processing by the proximal tubule: physiological, pathological, and therapeutic implications	48
Mechanisms and physiological implications of cooperative gating of clustered ion channels	47
The physiological functions of human peroxisomes	47
Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology	47
The evolution of regulated cell death pathways in animals and their evasion by pathogens	45
What’s the buzz? The neuroscience and the treatment of tinnitus	45
Lymphatic vessels in cancer	44
Vascular mechanotransduction	44
Developmental and epileptic encephalopathies: from genetic heterogeneity to phenotypic continuum	43
Anti-protease Treatments Targeting Plasmin(ogen) and Neutrophil Elastase May Be Beneficial in Fighting COVID-19	43
Trained immunity: adaptation within innate immune mechanisms	43
Physiological roles of mammalian transmembrane adenylyl cyclase isoforms	41

Energy metabolism design of the striated muscle cell	38
Telomere-mediated lung disease	38
The superoxide radical switch in the biology of nitric oxide and peroxynitrite	36
Salivary gland function, development, and regeneration	36
The FGF/FGFR system in the physiopathology of the prostate gland	36
Principles of odor coding in vertebrates and artificial chemosensory systems	36
Microcircuits for spatial coding in the medial entorhinal cortex	34
Sympathetic and sensory-motor nerves in peripheral small arteries	34
Neutrophil extracellular traps in the pathology of cancer and other inflammatory diseases	33
CD38 in the age of COVID-19: a medical perspective	32
The science and engineering behind sensitized brain-controlled bionic hands	32
Development and physiological functions of the lymphatic system: insights from human genetic studies of primary lymphedema	32
Folding brains: from development to disease modeling	31
Development of antifibrotic therapy for stricturing Crohn’s disease: lessons from randomized trials in other fibrotic diseases	31
Circadian clocks of the kidney: function, mechanism, and regulation	30
Impact of Respiratory Syncytial Virus Infection on Host Functions: Implications for Antiviral Strategies	30
Cellular senescence and cardiovascular diseases: moving to the “heart” of the problem	29
Multisystem physiological perspective of human frailty and its modulation by physical activity	28
Consideration of Tranexamic Acid Administration to COVID-19 Patients	25
The role of junctophilin proteins in cellular function	25
Protease-activated receptors in health and disease	24
Lipodystrophy: A paradigm for understanding the consequences of "overloading" adipose tissue	24
Clonal hematopoiesis, somatic mosaicism, and age-associated disease	24
The molecular athlete: exercise physiology from mechanisms to medals	24