OOIR: Observatory of International Research

Papers

(The median citation count of Physiological Reviews is 26. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Making a good egg: human oocyte health, aging, and in vitro development	406
Corrigendum for Lutsenko et al., volume 105, 2025, p. 441–491	398
Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and Ca²⁺ signaling	364
Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries	299
SIRT7: the seventh key to unlocking the mystery of aging	283
Implications of the NADase CD38 in COVID pathophysiology	234
Systematic reviews for basic scientists: a different beast	227
Comparative physiological anthropogeny: exploring molecular underpinnings of distinctly human phenotypes	223
A comprehensive review of the neuroscience of ingestion: the physiological control of eating: signals, neurons, and networks	202
Programmed cell death and tissue regeneration: a link that should be resolved	185
Glycerolipid Cycling in Thermogenesis, Energy Homeostasis, Signaling, and Diseases	185
Sensing molecular carbon dioxide: a translational focus for respiratory disease	185
The physiopathology of brain-derived neurotrophic factor	185
Rho GTPase signaling in cancer progression and dissemination	183
Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms	156
Contribution of adaptive immunity to human COPD and experimental models of emphysema	155
Immunotherapy for atherosclerosis	145
Neuronal glucose sensing mechanisms and circuits in the control of insulin and glucagon secretion	141
Understanding COVID-19 susceptibility and presentation based on its underlying physiology	131
Mitochondrial calcium exchange in physiology and disease	130
NETosis creates a link between diabetes and Long COVID	127
The physiological control of eating: signals, neurons, and networks	126
Calcium-release channels: structure and function of IP₃ receptors and ryanodine receptors	126
The enteric nervous system	126
Molecular dissection of the role of ACE2 in glucose homeostasis	123

A primer on obesity-related cardiomyopathy	116
Complex physiology and clinical implications of time-restricted eating	116
Lipids shape brain function through ion channel and receptor modulations: physiological mechanisms and clinical perspectives	105
Genome-wide association studies of cardiovascular disease	103
The molecular athlete: exercise physiology from mechanisms to medals	102
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs	102
How development sculpts hippocampal circuits and function	100
Redox signaling in the pancreas in health and disease	92
Physiological roles of mammalian transmembrane adenylyl cyclase isoforms	90
Determinants, maintenance, and function of organellar pH	87
The human placenta and its role in reproductive outcomes revisited	86
The anterior chamber of the eye technology and its anatomical, optical, and immunological bases	84
The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes	81
Bioenergetics: the evolutionary basis of progressive kidney disease	81
Is Notch1 a neglected vascular mechanosensor?	78
Gravity, Microgravity and Artificial Gravity: Physiological Effects, Implementation and Applications	72
Recent advances in alcohol metabolism: from the gut to the brain	72
Principles of odor coding in vertebrates and artificial chemosensory systems	71
NADPH oxidases: redox regulation of cell homeostasis and disease	71
Community-acquired bacterial coinfections and COVID-19	70
Wonder of wonders, miracle of miracles: the unprecedented speed of COVID-19 science	69
Nanodomain cAMP signaling in cardiac pathophysiology: potential for developing targeted therapeutic interventions	68
Development of antifibrotic therapy for stricturing Crohn’s disease: lessons from randomized trials in other fibrotic diseases	68
Physiologic mechanisms underlying polycystic kidney disease	67
Transforming the concept of connectivity: unveiling tunneling nanotube biology and their roles in brain development and neurodegeneration	65
The elusive cephalic phase insulin response: triggers, mechanisms, and functions	65
Evolutionarily conserved transcription factors as regulators of longevity and targets for geroprotection	64
Fluid transport in the brain	61
Pathophysiology of syncope: current concepts and their development	60
Navigating the multifaceted intricacies of the Na⁺-Cl⁻ cotransporter, a highly regulated key effector in the control of hydromineral homeostasis	60
Mechanisms of SARS-CoV-2-associated anosmia	59
Trained immunity: adaptation within innate immune mechanisms	59
Adhesion G protein-coupled receptors: structure, signaling, physiology, and pathophysiology	58
The physiological functions of human peroxisomes	56
Ca²⁺ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract	56
Modulating vertebrate physiology by genomic fine-tuning of GPCR functions	54
Biomarkers of aging: from molecules and surrogates to physiology and function	54
Altered islet prohormone processing: a cause or consequence of diabetes?	52
Membrane adhesion junctions regulate airway smooth muscle phenotype and function	52
Cannabinoid treatments in epilepsy and seizure disorders	52
Phosphodiesterase in heart and vessels: from physiology to diseases	50
Sperm bauplan and function and underlying processes of sperm formation and selection	49
Protease-activated receptors in health and disease	48
The neurobiology of parenting and infant-evoked aggression	47
Human temperature regulation under heat stress in health, disease, and injury	47
Salivary gland function, development, and regeneration	46
Cysteine-based redox sensors in the cardiovascular system: from identification to physiology and drug discovery	45
Deconstructing the GWAS library: next-generation GWAS	42
Uterine fibroids	40
Multiscale structure and function of the aortic valve apparatus	40

Mechanisms of myosin II force generation: insights from novel experimental techniques and approaches	39
Sympathetic circuits regulating hepatic glucose metabolism: where we stand	36
Vascular mechanotransduction	34
Hepatic glucagon action: beyond glucose mobilization	33
The osteocyte as a signaling cell	32
Mesenchymal condensation in tooth development and regeneration: a focus on translational aspects of organogenesis	32
Extracellular vesicles and the lung: from disease pathogenesis to biomarkers and treatments	32
Windows into stress: a glimpse at emerging roles for CRH^PVN neurons	31
The multiple roles of salt-inducible kinases in regulating physiology	31
Lymphatic vessels in cancer	31
Examining the shared etiology of psychopathology with genome-wide association studies	31
Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology	30
Mechanisms and physiological implications of cooperative gating of clustered ion channels	29
Physiological basis for xenotransplantation from genetically modified pigs to humans	29
Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training	29
Corrigendum for Eisner et al., volume 103, 2023, p. 2767–2845	28
The ion channels of endomembranes	27
Psychophysiological foundations of human physical activity behavior and motivation: theories, systems, mechanisms, evolution, and genetics	26
Neuropathological links between T2DM and LOAD: systematic review and meta-analysis	26
A comprehensive view of muscle glucose uptake: regulation by insulin, contractile activity, and exercise	26