Physiological Reviews

Papers
(The TQCC of Physiological Reviews is 73. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
The flux of energy in critical illness and the obesity paradox521
Modulating vertebrate physiology by genomic fine-tuning of GPCR functions444
Energy metabolism design of the striated muscle cell304
Altitude physiology then (1921) and now (2021): Meat on the bones288
Mechanisms and physiological implications of cooperative gating of clustered ion channels282
Biomarkers of aging: from molecules and surrogates to physiology and function273
Climate change impacts on respiratory health: exposure, vulnerability, and risk262
Do hippocampal pyramidal cells respond to nonspatial stimuli?258
Recent insights into channelopathies252
Lipids shape brain function through ion channel and receptor modulations: physiological mechanisms and clinical perspectives247
Degenerate neuronal and circuit mechanisms important for generating rhythmic motor patterns241
Mammalian copper homeostasis: physiological roles and molecular mechanisms232
The evolution of regulated cell death pathways in animals and their evasion by pathogens221
Heterogeneity of glutamatergic synapses: cellular mechanisms and network consequences207
Folding brains: from development to disease modeling202
Ceramides are fuel gauges on the drive to cardiometabolic disease194
Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and Ca2+ signaling173
Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveries152
Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training150
The choroid plexus: a missing link in our understanding of brain development and function148
Mitochondria in health, disease, and aging148
The FGF/FGFR system in the physiopathology of the prostate gland147
Ferroptosis: when metabolism meets cell death144
Role ofO-linkedN-acetylglucosamine protein modification in cellular (patho)physiology144
Genome-wide association studies of cardiovascular disease137
SIRT7: the seventh key to unlocking the mystery of aging126
Making a good egg: human oocyte health, aging, and in vitro development116
Cardiac transmembrane ion channels and action potentials: cellular physiology and arrhythmogenic behavior107
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs106
Understanding coenzyme Q105
Neuropathological links between T2DM and LOAD: systematic review and meta-analysis103
The molecular athlete: exercise physiology from mechanisms to medals97
The role of junctophilin proteins in cellular function96
Altered islet prohormone processing: a cause or consequence of diabetes?90
Corrigendum for Eisner et al., volume 103, 2023, p. 2767–284587
The TRP Channels Serving as Chemical-to-Electrical Signal Converter85
Redox signaling in the pancreas in health and disease85
Psycho-physiological foundations of human physical activity behavior and motivation: Theories, systems, mechanisms, evolution, and genetics84
The ion channels of endomembranes82
Mitochondrial quality control in health and in Parkinson’s disease81
Implications of the NADase CD38 in COVID pathophysiology81
Evolution of the diagnostic value of “the sugar of the blood”: hitting the sweet spot to identify alterations in glucose dynamics79
Moving immune therapy forward targeting tme77
Bone metastasis: mechanisms, therapies, and biomarkers77
Cannabinoid treatments in epilepsy and seizure disorders77
Circadian clocks of the kidney: function, mechanism, and regulation77
CD38 in the age of COVID-19: a medical perspective75
The role of globins in cardiovascular physiology75
How development sculpts hippocampal circuits and function75
Leveraging physiology and artificial intelligence to deliver advancements in health care73
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