Planta Medica

Article	Citations
Rosmarinic Acid–Human Pharmacokinetics and Health Benefits	71
Challenges at the Time of COVID-19: Opportunities and Innovations in Antivirals from Nature	68
Verbena officinalis (Common Vervain) – A Review on the Investigations of This Medicinally Important Plant Species	37
Artemisia annua – Importance in Traditional Medicine and Current State of Knowledge on the Chemistry, Biological Activity and Possible Applications	30
Punica granatum Leaf Ethanolic Extract and Ellagic Acid as Inhibitors of Zika Virus Infection	29
Quality Control of Herbal Medicines: From Traditional Techniques to State-of-the-art Approaches	28
Salazinic Acid-Derived Depsidones and Diphenylethers with α-Glucosidase Inhibitory Activity from the Lichen Parmotrema dilatatum	27
A Mechanistic Review on Medicinal Mushrooms-Derived Bioactive Compounds: Potential Mycotherapy Candidates for Alleviating Neurological Disorders	26
Medicinal Plants in the Treatment of Depression: Evidence from Preclinical Studies	26
α-Glucosidase Inhibitory Depsidones from the Lichen Parmotrema tsavoense	23
Antiviral and Virucidal Properties of Essential Oils and Isolated Compounds – A Scientific Approach	22
Cannabis sativa and Skin Health: Dissecting the Role of Phytocannabinoids	22
A Systematic Review on Secondary Metabolites of Paecilomyces Species: Chemical Diversity and Biological Activity	21
A Review of the Phytochemistry, Traditional Uses and Biological Activities of the Essential Oils of Genus Teucrium	19
Pharmacokinetics and Safety of Mitragynine in Beagle Dogs	18
Natural Products as a Source of Inspiration for Novel Inhibitors of Advanced Glycation Endproducts (AGEs) Formation	18
Lichen Depsidones with Biological Interest	18
Phenolic-rich Pomegranate Peel Extract: In Vitro, Cellular, and In Vivo Activities for Skin Hyperpigmentation Treatment	16
Medicinal Plants for Insomnia Related to Anxiety: An Updated Review	15
Volatile Antimicrobial Agents and In Vitro Methods for Evaluating Their Activity in the Vapour Phase: A Review	14
Enhanced Oral Bioavailability and Improved Biological Activities of a Quercetin/Resveratrol Combination Using a Liquid Self-Microemulsifying Drug Delivery System	14
Beta-Glucuronidase Inhibition by Constituents of Mulberry Bark	14
Composition and Antibacterial Effect of Mint Flavorings in Candies and Food Supplements	14
Biochanin A, the Most Potent of 16 Isoflavones, Induces Relaxation of the Coronary Artery Through the Calcium Channel and cGMP-dependent Pathway	14
Brown-Algae Polysaccharides as Active Constituents against Nonalcoholic Fatty Liver Disease	14

Wild Strawberry, Blackberry, and Blueberry Leaf Extracts Alleviate Starch-Induced Hyperglycemia in Prediabetic and Diabetic Mice	13
Ginkgo biloba and Its Constituent 6-hydroxykynurenic-acid as well as Its Proanthocyanidins Exert Neurorestorative Effects against Cerebral Ischemia	13
Promising Medicinal Plants with Diuretic Potential Used in Brazil: State of the Art, Challenges, and Prospects	13
Investigation of Antiplasmodial Effects of Terpenoid Compounds Isolated from Myrrh	13
HPLC-UV, Metabarcoding and Genome Skims of Botanical Dietary Supplements: A Case Study in Echinacea	13
Cacao Bean Polyphenols Inhibit Cardiac Hypertrophy and Systolic Dysfunction in Pressure Overload-induced Heart Failure Model Mice	12
Antiviral Medicinal Plants of Veterinary Importance: A Literature Review	12
Essential Oils as a Potential Treatment Option for Pediculosis	12
Nanoencapsulation of Plant Volatile Organic Compounds to Improve Their Biological Activities	11
Chemical Ecology in Insect-microbe Interactions in the Neotropics	11
ELISA for the Detection of the Prohibited Doping Agent Higenamine	11
Erianthridin Induces Non-small Cell Lung Cancer Cell Apoptosis through the Suppression of Extracellular Signal-regulated Kinase Activity	11
In Vitro and In Vivo Metabolic Activation of Obacunone, A Bioactive and Potentially Hepatotoxic Constituent of Dictamni Cortex	11
Chemical Characterization of Lavandula dentata Essential Oil Cultivated in Chile and Its Antibiofilm Effect against Candida albicans	10
Regulatory Perspectives of Pyrrolizidine Alkaloid Contamination in Herbal Medicinal Products	10
Novel Insights into Pyrrolizidine Alkaloid Toxicity and Implications for Risk Assessment: Occurrence, Genotoxicity, Toxicokinetics, Risk Assessment–A Workshop Report	10
Chemical Constituents from Physalis Calyx seu Fructus and Their Inhibitory Effects against Oxidative Stress and Inflammatory Response	10
A Proposal Towards a Rational Classification of the Antimicrobial Activity of Acetone Tree Leaf Extracts in a Search for New Antimicrobials	10
Characterization of Maca (Lepidium meyenii/Lepidium peruvianum) Using a Mass Spectral Fingerprinting, Metabolomic Analysis, and Genetic Sequencing Approach	9
Britanin Exhibits Potential Inhibitory Activity on Human Prostate Cancer Cell Lines Through PI3K/Akt/NF-κB Signaling Pathways	9
A Novel Peptide Derived from Ginger Induces Apoptosis through the Modulation of p53, BAX, and BCL2 Expression in Leukemic Cell Lines	9
Review of Studies on Phlomis and Eremostachys Species (Lamiaceae) with Emphasis on Iridoids, Phenylethanoid Glycosides, and Essential Oils	9
Rosmarinic Acid Intravitreal Implants: A New Therapeutic Approach for Ocular Neovascularization	9
Anti-Inflammatory Activity of the Compositae Family and Its Therapeutic Potential	9
Phyllobilins – Bioactive Natural Products Derived from Chlorophyll – Plant Origins, Structures, Absorption Spectra, and Biomedical Properties	9
Pressurized Natural Deep Eutectic Solvent Extraction of Galanthamine and Related Alkaloids from Narcissus pseudonarcissus	9
The Potential Application of Pentacyclic Triterpenoids in the Prevention and Treatment of Retinal Diseases	8
Protection of Beta Boswellic Acid against Streptozotocin-induced Alzheimerʼs Model by Reduction of Tau Phosphorylation Level and Enhancement of Reelin Expression	8
Berberine Ameliorates Glucose Metabolism in Diabetic Rats through the alpha7 Nicotinic Acetylcholine Receptor-Related Cholinergic Anti-Inflammatory Pathway	8
Pyrrolizidine Alkaloid Contamination in Medicinal Plants: Regulatory Requirements and Their Impact on Production and Quality Control of Herbal Medicinal Products	8
Prospecting and Identifying Phyllanthus amarus Lignans with Antileishmanial and Antitrypanosomal Activity	8
Cytotoxicity and Antiviral Activities of Haplophyllum tuberculatum Essential Oils, Pure Compounds, and Their Combinations against Coxsackievirus B3 and B4	8
Rhytidhyesters A – D, 4 New Chlorinated Cyclopentene Derivatives from the Endophytic Fungus Rhytidhysteron sp. BZM-9	8
Characterization of Antibacterial Proanthocyanidins of Dalbergia monetaria, an Amazonian Medicinal Plant, by UHPLC-HRMS/MS	8
Bioactive Properties of the Aqueous Extracts of Endophytic Fungi Associated with Scots Pine (Pinus sylvestris) Roots	8
New Pyrrolobenzoxazine Sesquiterpenoid Derivatives from the Fungus Talaromyces trachyspermus	8
Berberine Regulates GPX4 to Inhibit Ferroptosis of Islet β Cells	8
Kratom (Mitragyna speciosa) Validation: Quantitative Analysis of Indole and Oxindole Alkaloids Reveals Chemotypes of Plants and Products	8
Low Piperine Fractional Piper nigrum Extract Enhanced the Antitumor Immunity via Regulating the Th1/Th2/Treg Cell Subsets on NMU-Induced Tumorigenesis Rats	8
Novel Piperidine and 3,4-dihydro-2H-pyrrole Alkaloids from Tilia platyphyllos and Tilia cordata Flowers	8
13C NMR Dereplication Using MixONat Software: A Practical Guide to Decipher Natural Products Mixtures	8
Anticancer Potential of Compounds from the Brazilian Blue Amazon	7
Artocarpus lacucha Extract and Oxyresveratrol Inhibit Glucose Transporters in Human Intestinal Caco-2 Cells	7
In Vitro and In Silico Evaluation of ACE2 and LOX Inhibitory Activity of Origanum Essential Oils and Carvacrol	7
Cardiovascular Effects Induced by Fruit Peels from Passiflora edulis in Hypertensive Rats and Fingerprint Analysis by HPLC-ESI-MSn spectrometry	7
Antimycobacterial Activity of Alkaloids and Extracts from Tabernaemontana alba and T. arborea	7
Bulbine natalensis (currently Bulbine latifolia) and select bulbine knipholones modulate the activity of AhR, CYP1A2, CYP2B6, and P-gp	7
Screening of Bufadienolides from Toad Venom Identifies Gammabufotalin as a Potential Anti-inflammatory Agent	7
Medicinal Plants in the Treatment of Depression. II: Evidence from Clinical Trials	7
A Detailed View on the Proanthocyanidins in Ginkgo Extract EGb 761	7

Medical Devices Made of Substances: Possible Innovation and Opportunities for Complex Natural Products	7
Medicinal Plants for the Treatment of Mental Diseases in Pregnancy: An In Vitro Safety Assessment	7
Ethnoveterinary Remedies Used in Avian Complementary Medicine in Selected Communal Areas in Zimbabwe	7
Antiprotozoal activities of Triterpenic Acids and Ester Derivatives Isolated from the Leaves of Vitellaria paradoxa	7
Sulfation of Quercitrin, Epicatechin and Rutin by Human Cytosolic Sulfotransferases (SULTs): Differential Effects of SULT Genetic Polymorphisms	7
Bioaccessibility and Absorption of Flavonoid C-glycosides from Abrus mollis Using Simulated Digestion, Caco-2 Cell, and In Situ Single-pass Perfusion Models	7
Molecular Networking Discloses the Chemical Diversity of Flavonoids and Selaginellins in Selaginella convoluta	7
Isolation and Characterization of Acetylcholinesterase Inhibitors from Piper longum and Binding Mode Predictions	6
Phytogenic Compounds for Enhancing Intestinal Barrier Function in Poultry–A Review	6
Cytotoxic Agents in the Minor Alkaloid Groups of the Amaryllidaceae	6
Pharmacokinetic Properties of Moracin C in Mice	6
Phloridzin Highly Accumulated in Malus rockii Rehder and Its Structure Revision and Hypolipidemic Activity	6
Total Flavonoids of Bidens pilosa Ameliorates Bone Destruction in Collagen-Induced Arthritis	6
Folklore, Animal Self-Medication, and Phytotherapy–Something Old, Something New, Something Borrowed, Some Things True	6
The Role of Kinetics as Key Determinant in Toxicity of Pyrrolizidine Alkaloids and Their N-Oxides	6
Cytotoxic, Antioxidant, and Antidiabetic Activities versus UPLC-ESI-QTOF-MS Chemical-Profile Analysis of Ipomoea aquatica Fractions	6
A New Diterpene and Anti-inflammatory Sesquiterpene Lactones from Sigesbeckia orientalis	6
The Potential of Biologically Active Brazilian Plant Species as a Strategy to Search for Molecular Models for Mosquito Control	6
Achiote (Bixa orellana) Lipophilic Extract, Bixin, and δ-tocotrienol Effects on Lifespan and Stress Resistance in Caenorhabditis elegans	6
Inhibition of Proinflammatory Cytokine Release by Flavones and Flavanones from the Leaves of Dracaena steudneri Engl.	6
Resveratrol Protects BEAS-2B Cells against Erastin-Induced Ferroptosis through the Nrf2/Keap1 Pathway	6
Protective Effects of Total Alkaloids from Menispermum dauricum against Airway Inflammation in Asthmatic Mice	6
Coffee Leaves: An Upcoming Novel Food?	6
Identification and Quantification of Polymethoxylated Flavonoids in Different Citrus Species Using UPLC-QTOF-MS/MS and HPLC-DAD	6
Infraspecific Chemical Variability and Biological Activity of Casearia sylvestris from Different Brazilian Biomes	5
Hydroalcoholic Extract of Myrcia bella Loaded into a Microemulsion System: A Study of Antifungal and Mutagenic Potential	5
Cytotoxicity of Poupartone B, an Alkyl Cyclohexenone Derivative from Poupartia borbonica, against Human Cancer Cell Lines	5
Cytochalasan Alkaloids as TRAIL Sensitizers from an Endophytic Fungus Chaetomium sp.	5
Involvement of the Benzodiazepine Site in the Anticonvulsant Activity of Tapinanthus globiferus against Pentylenetetrazole-induced Seizures in Mice	5
Withanolides from Withania somnifera Ameliorate Neutrophil Infiltration in Endotoxin-Induced Peritonitis by Regulating Oxidative Stress and Inflammatory Cytokines	5
Cornus sanguinea Fruits: a Source of Antioxidant and Antisenescence Compounds Acting on Aged Human Dermal and Gingival Fibroblasts	5
Natural Prenylated Xanthones as Potential Inhibitors of PI3k/Akt/mTOR Pathway in Triple Negative Breast Cancer Cells	5
Identification of TRPV1 Ion Channels Agonists of Tropaeolum tuberosum in Human Skin Keratinocytes	5
Placental Passage of Protopine in an Ex Vivo Human Perfusion System	5
Undescribed C-Glycosylflavones from Corn Silk and Potential Anti-inflammatory Activity Evaluation of Isolates	5
Optimization and Evaluation of Self-nanoemulsifying Drug Delivery System for Enhanced Bioavailability of Plumbagin	5
Accumulation of the Major Components from Polygoni Multiflori Radix in Liver and Kidney after Its Long-Term Oral Administrations in Rats	5
Comparative Transcriptome Analysis Reveals Candidate Genes Involved in Isoquinoline Alkaloid Biosynthesis in Stephania tetrandra	5
Quantification of Silymarin in Silybi mariani fructus: Challenging the Analytical Performance of Benchtop vs. Handheld NIR Spectrometers on Whole Seeds	5
cis-Aconitic Acid, a Constituent of Echinodorus grandiflorus Leaves, Inhibits Antigen-Induced Arthritis and Gout in Mice	5
Diterpenoids from Leaves of Cultivated Plectranthus ornatus	5
Acaricidal Activity of Artemisia nilagirica Leaves Against Rhipicephalus (Boophilus) annulatus Ticks	5
Beyond the Psychoactive Effects of Ayahuasca: Cultural and Pharmacological Relevance of Its Emetic and Purging Properties	5
Herbal Products in Postsurgical Wound Healing – Incision, Excision and Dead Space Wound Models	5
Extract of the Aerial Part of Polygala tenuifolia Attenuates d-Galactose/NaNO2-induced Learning and Memory Impairment in Mice	5
In vitro and In Vivo Immunomodulatory Activity of Physalis angulata Concentrated Ethanolic Extract	5
Inactivation of Herpes Simplex Virus by Photosensitizing Anthraquinones Isolated from Heterophyllaea pustulata	4
Oxidized Forms of Olive Oil Secoiridoids: Semisynthesis, Identification and Correlation with Quality Parameters	4
Differentiation between Cistus L. (Sub-) Species (Cistaceae) Using NMR Metabolic Fingerprinting	4
Ouratea spectabilis and its Biflavanone Ouratein D Exert Potent Anti-inflammatory Activity in MSU Crystal-induced Gout in Mice	4
White Sage (Salvia apiana)–a Ritual and Medicinal Plant of the Chaparral: Plant Characteristics in Comparison with Other Salvia Species	4
Update on Phytochemical and Biological Studies on Rocaglate Derivatives from Aglaia Species	4
Artemisiae Iwayomogii Herba Inhibits Growth, Motility, and the PI3K/AKT/mTOR Signaling Pathway in Hepatocellular Carcinoma Cells	4
Prenylated Acylphloroglucinols from Hypericum jovis with Anti-inflammatory Potential	4
High-performance Countercurrent Chromatography to Access Rhodiola rosea Influenza Virus Inhibiting Constituents	4
Screening of Antimicrobial Activity of Essential Oils against Bovine Respiratory Pathogens – Focusing on Pasteurella multocida	4
Development, Validation and Application of a UHPLC-MS Method for the Quantification of Chios Mastic Gum Triterpenoids in Human Plasma	4
Quantitative Proteomics Based on iTRAQ Reveal that Nitidine Chloride Induces Apoptosis by Activating JNK/c-Jun Signaling in Hepatocellular Carcinoma Cells	4
Antibacterial Compounds from Mushrooms: A Lead to Fight ESKAPEE Pathogenic Bacteria?	4
Codonopsis lanceolata Contributes to Ca2+ Homeostasis by Mediating SOCE and PLC/IP3 Pathways in Vascular Endothelial and Smooth Muscle Cells	4
Natural Polyketides Isolated from the Endophytic Fungus Phomopsis sp. CAM212 with a Semisynthetic Derivative Downregulating the ERK/IκBα Signaling Pathways	4
Scutellaria baicalensis Pith-decayed Root Inhibits Macrophage-related Inflammation Through the NF-κB/NLRP3 Pathway to Alleviate LPS-induced Acute Lung Injury	4
Evaluation of Cocoa Bean Shell Antimicrobial Activity: A Tentative Assay Using a Metabolomic Approach for Active Compound Identification	4
Syzygium aromaticum Reduces Diabetes-induced Glucotoxicity via the NRF2/Glo1 Pathway	4
Desmethylbellidifolin Attenuates Dextran Sulfate Sodium-Induced Colitis: Impact on Intestinal Barrier, Intestinal Inflammation and Gut Microbiota	4
Neuroprotective Properties of Chlorogenic Acid and 4,5-Caffeoylquinic Acid from Brazilian arnica (Lychnophora ericoides) after Acute Retinal Ischemia	4
Correction: VC8 Gaseous methyl jasmonate can increase hypericins content in Hypericum perforatum aseptic plants	4
Differential Effects of Components in Artemisia annua Extract on the Induction of Drug-Metabolizing Enzyme Expression Mediated by Nuclear Receptors	4
Acrotrione B, a Prenylated and Highly Oxidized Xanthenoid with Antibacterial and Anti-proliferative Activities from the Roots of Acronychia pedunculata	4
Studies on Bignoniaceae: Newbouldiosides D – F, Minor Phenylethanoid Glycosides from Newbouldia laevis, and New Flavonoids from Markhamia zanzibarica and Spathodea campanulata	4
Medicinal Plants for Prophylaxis and Therapy of Common Infectious Diseases In Poultry–A Systematic Review of In Vivo Studies	4
Quality Requirements for Medicinal Cannabis and Respective Products in the European Union – Status Quo	4
Cardioprotective Function of Green Rooibos (Aspalathus linearis) Extract Supplementation in Ex Vivo Ischemic Prediabetic Rat Hearts	4
Profiling and Quantification of the Key Phytochemicals from the Drumstick Tree (Moringa oleifera) and Dietary Supplements by UHPLC-PDA-MS	4
The Role of Herbal Medicine in Cholangiocarcinoma Control: A Systematic Review	4
Seven-day Oral Intake of Orthosiphon stamineus Leaves Infusion Exerts Antiadhesive Ex Vivo Activity Against Uropathogenic E. coli in Urine Samples	4
Pharmacokinetics of Five Alkaloids and their Metabolites in Normal and Diabetic Rats after Oral Administration of Rhizoma coptidis	4
Bio-evaluation of Untapped Alkaloids from Vinca minor Enriched by Methyl-jasmonate-induced Stress: an Integrated Approach	4
Peperomin E Induces Apoptosis and Cytoprotective Autophagy in Human Prostate Cancer DU145 Cells In Vitro and In Vivo	4
(+)-Magnolin Enhances Melanogenesis in Melanoma Cells and Three-Dimensional Human Skin Equivalent; Involvement of PKA and p38 MAPK Signaling Pathways	4

New Sulfoxide-Containing Derivatives from the Resin of Ferula sinkiangensis	4
Activity of THC, CBD, and CBN on Human ACE2 and SARS-CoV1/2 Main Protease to Understand Antiviral Defense Mechanism	4