OOIR: Observatory of International Research

Papers

(The TQCC of Steroids is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Editorial Board	36
Effects of estradiol, progesterone or cAMP on expression of PGRMC1 and progesterone receptor in a xenograft model of human endometrium and in endometrial cell culture	32
Mitochondrial dysfunction and cardiac ischemia/reperfusion injury are attenuated by nandrolone: Role of JAK-STAT3 pathway	32
Retraction notice to “Thyroid hormone is a MAPK-dependent growth factor for thyroid cancer cells and is anti-apoptotic” [Steroids 72(2) 2007 180–187]	27
Cortisol resistance in the degu (Octodon degus)	25
Ursane hybrids with 5-amino-1,2,3,4-thiatriazole, 1-tetrazole-5-thione, and 1-tetrazole-5-amines and study of their inhibition of main SARS-CoV-2 protease	25
Roles of equol and the PI3K/Akt signaling pathway in the cardioprotective effects of enteral daidzein against ischemia–reperfusion injury in isolated rat hearts	24
The roles of methylprednisolone treatment in patients with COVID-19: A systematic review and meta-analysis	24
Isolation, structural elucidation of new phytoecdysteroids from Ajuga decumbens Thunb	24
Acute serum protein and cytokine response of single dose of prednisone in adult volunteers	22
Nandrolone decanoate induced kidney injury through miRNA-146a targeting IRAK1 and TRAF6 via activation of the NF-κB pathway: The effect of moderate exercise	22
Membrane progesterone receptors on the cell membrane: A review highlighting potential export motifs in mPRα regulating its trafficking to the cell surface	20
Mineralocorticoid receptor antagonism of vamorolone: Evidence from LIONHEART and VISION-DMD clinical trials	20
Synthesis of methotrexate-betulonic acid hybrids and evaluation of their effect on artificial and Caco-2 cell membranes	20
Ligand-based analysis of the antifungal potential of phytosterols and triterpenes isolated from Cryptostegia grandiflora against Candida auris FKBP12	19
Functions of dehydroepiandrosterone in relation to breast cancer	19
17beta-estradiol alleviates contusion-induced skeletal muscle injury by decreasing oxidative stress via SIRT1/PGC-1α/Nrf2 pathway	18
Biotransformation of hydrocortisone succinate with whole cell cultures of Monascus purpureus and Cunninghamella echinulata	18
Acquired 11β-Hydroxylase deficiency in etomidate and (Iso)propoxate abusers: A nascent endocrine condition	18
An improved synthesis of azedarachol	17
Synthesis, antifungal evaluation, and molecular docking studies of steroidal thiazolopyrimidines	17
The location of estrogen receptor variant ER-α36 is associated with the invasion of glioblastoma	16
Epoxide of diosgenin acetate synthesis: DoE for diastereoselective yield optimization, antimicroibial, antioxidant and antiproliferative effects	15
Androgenic steroids in Over-the-Counter dietary Supplements: Analysis for association with adverse health effects	15
Drugs possessing aryloxypropanamine pharmacophore, duloxetine, dapoxetine and propranolol, increase allopregnanolone in rat brain: Possible involvement of allopregnanolone in their central nervous sys	15

Target-specific high-throughput screening of anti-inflammatory phytosteroids for autoimmune diseases: A molecular docking-dynamics simulation approach	15
Editorial Board	15
Synthesis and antitumor activity of some cholesterol-based selenocyanate compounds	14
Antitumor potential of novel 5α,6β-dibromo steroidal D-homo lactone	14
Ascorbic acid Mitigates behavioural disturbances associated with letrozole-induced PCOS via switching-off JAK2/STAT5 and JAK2/ERK1/2 pathways in rat hippocampus	13
Synthesis, anti-leukemia activity, and molecular docking of novel 3,16-androstenedione derivatives	13
Insight into isolation and elucidation of cytotoxic ergostanoids from the mushroom Sarcosphaera crassa (Santi) Pouzar: An edible mushroom	13
Characterization and functional analysis of BmSR-B1 for phytosterol uptake	13
Unleashing the pharmacological potential of taste receptors in reproductive processes beyond their gustatory role	13
Exploring the urate lowering properties of Erigeron annuus Lin. and phytosterol contributions: In vitro assays and in silico approaches	13
Polycystic ovary syndrome: Insights into its prevalence, diagnosis, and management with special reference to gut microbial dysbiosis	12
The effect of transdermal 17β-estradiol combined with norethisterone acetate treatment on the lipid profile in postmenopausal women: A meta-analysis and systematic review of randomized controlled tria	12
Systemic corticosteroid use and cardiovascular risk in patients hospitalized for pneumonia	12
Response to ‘25-OH Vitamin D concentrations measured by LC-MS/MS are equivalent in serum and EDTA plasma’	12
Theoretical study of the pyridyl-cholestane formation pathway using DFT: A stepwise mechanistic approach	12
Editorial Board	12
TFA-mediated stereoselective aza-Michael addition for the synthesis of 3β-arylamine derivatives of withaferin A and evaluation of their anticancer potential	12
Progestogens exhibit progestogen-, promoter- and isoform-specific effects via the progesterone receptor	11
Glucocorticoid signaling and the impact of high-fat diet on adipogenesis in vivo	11
Synthesis of hyocholic acid and its derivatization with sodium periodate to distinguish it from cholic acid by mass spectrometry	11
Nutrient manipulation regulates growth and steroidal alkaloid production in plant cultures of Solanum viarum Dunal	11
Antibacterial activity of withanolides and their structure-activity relationship	11
Investigating the influence of estrous cycle-dependent hormonal changes on neurogenesis in adult mice	11
Retraction notice to “Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2“ [STE 202 (2024) 109351]	11
Genetic insights into vitamin D deficiency: a case-control study of GC and CYP24A1 gene polymorphism	10
Synthesis and cytotoxicity of betulin and betulinic acid derived 30-oxo-amides	10
The effect of various corticosteroids in the hospitalized patients with moderate and severe COVID-19: A tertiary hospital experience	10
The role of estrogen metabolites in human ovarian function	10
A novel role of catalase in cholesterol uptake of Helicobacter pylori	10
Endocannabinoid and steroid hormone levels during and after pregnancy in fingernail samples from mothers and their infants	9
Estrogen signaling in healthy and tumor brain	9
Filamin A in triple negative breast cancer	9
Triazole-estradiol analogs: A potential cancer therapeutic targeting ovarian and colorectal cancer	9
European Network for oxysterol research (ENOR): 10th ENOR symposium – Web meeting	9
Shatavarin-IV, a steroidal saponin from Asparagus racemosus, inhibits cell cycle progression and epithelial-to-mesenchymal transition in AGS cells under hyperglycemic conditions	9
Testosterone replacement has a beneficial effect on the hemostatic system by altered gene expression of coagulation factors	9
Kuwanon C inhibits proliferation and induction of apoptosis via the intrinsic pathway in MDA-MB231 and T47D breast cancer cells	9
Editorial Board	9
Synthesis and characterization of epoxide impurities of abiraterone acetate	9
Vitamin D potentiation of metformin hepatoprotective activities: Concurrent targeting of carbohydrate enzymatic pathways and PCSK9/AGEs-regulated oxidative stress mechanisms in type 2 diabetic male Wi	9
Editorial Board	9
Evaluation of structural and thermodynamic insight of ERβ with DPN and derivatives through MMGBSA/MMPBSA methods	8
Synthesis, NMR and X-ray characterization of dibenzoannulated dimeric steroid spiroketals. Evaluation of cytotoxicity and anti-inflammatory activity	8
Anti-cancer activity, and molecular docking of novel hybrid heterocyclic steroids revealed promising anti-hepatocellular carcinoma agent: Implication of cyclin dependent kinase-2 pathway	8
Editorial Board	8
Dehydroepiandrosterone supplementation improves diminished ovarian reserve clinical and in silico studies	8
Application of a fluorine strategy in the lead optimization of betulinic acid to the discovery of potent CD73 inhibitors	8
An overview on androgen-mediated actions in skeletal muscle and adipose tissue	8
New secondary metabolites from the soil-derived Aspergillus versicolor QC812	8
Corrigendum to “Effects of neural-derived estradiol on actin polymerization and synaptic plasticity-related proteins in prefrontal and hippocampal cells of mice” [Steroids 177 (2022) 108935]	8

An association of VDR gene polymorphism in hypovitaminosis D mediated secondary hyperparathyroidism in adolescent girls; a tertiary hospital study in central India	8
Synthesis and anti-inflammatory effects of Δ7-Cholestenol and Δ8(14)-Cholestenol derivatives	8
Steroids from the mushroom Ganoderma shandongense and their AChE inhibitory activities	8
Formation of nitrogen-containing six-membered heterocycles on steroidal ring system: A review	8
A hormonal side effect of anabolic steroids among a sample of Baghdad male bodybuilders	8
Corrigendum to “Advances in the understanding of androgen receptor structure and function and in the development of next-generation AR-targeted therapeutics”. [Steroids 210 (2024) 109486]	8
20-Hydroxyecdysone bioavailability and pharmacokinetics in Gerbillus tarabuli, a gerbil model for metabolic syndrome studies	8
Navigating nonalcoholic fatty liver disease (NAFLD): Exploring the roles of estrogens, pharmacological and medical interventions, and life style	8
Rfamide-related peptide-3(RFRP-3) receptor gene is expressed in mouse ovarian granulosa cells: Potential role of RFRP-3 in steroidogenesis and apoptosis	7
BSS-4, a diosgenin analogue, reduces carrageenan-induced paw inflammation in rat	7
Synthesis of fully functionalized spirostanic 1,2,3-triazoles by the three component reaction of diosgenin azides with acetophenones and aryl aldehydes and their biological evaluation as antiprolifera	7
Expression of pregnenolone-synthesizing enzymes CYP11A1 and CYP1B1 in the human, rat, and mouse brain	7
Editorial Board	7
Validation of a LC-MS/MS method for establishing reference intervals and assessing diagnostic performance of urinary free cortisol and cortisone	7
Anti-apoptotic effects of diosgenin on ovariectomized hearts	7
Sonogashira coupling-based synthesis and in vitro cytotoxic evaluation of C-2 alkynyl derivatives of withaferin A	7
Mifepristone’s effects on depression- and anxiety-like behavior in rodents	7
Structures and functions of human placental aromatase and steroid sulfatase, two key enzymes in estrogen biosynthesis	7
Navigating a plethora of progesterone receptors: Comments on the safety/risk of progesterone supplementation in women with a history of breast cancer or at high-risk for developing breast cancer	7
A comprehensive update on phytochemistry, analytical aspects, medicinal attributes, specifications and stability of stigmasterol	7
An efficient regioconvergent synthesis of 3-aza-obeticholic acid	7
Mass spectrometric stochastic dynamic 3D structural analysis of mixture of steroids in solution – Experimental and theoretical study	7
The effect of vitamin D2 supplementation on vitamin D levels in humans: A time and dose–response meta-analysis of randomized controlled trials	7
Editorial Board	7
Editorial Board	7
Microwave-assisted one-pot multicomponent synthesis of steroidal pyrido[2,3-d]pyrimidines and their possible implications in drug development	7
Significance of vitamin D responsiveness on the etiology of vitamin D-related diseases	6
Intramuscular sex steroid hormones are reduced after resistance training in postmenopausal women, but not affected by estrogen therapy	6
Dexamethasone induces cancer mitigation and irreversible senescence in lung cancer cells via damaging cortical actin and sustained hyperphosphorylation of pRb	6
Natural products derived steroids as potential anti-leishmanial agents; disease prevalence, underlying mechanisms and future perspectives	6
The influence of the route of drug administration on the metabolic profile of trenbolone in doping control urine samples	6
The interpretation of immunometric, chromatographic and mass spectrometric data for steroids in diagnosis of endocrine disorders	6
Effect of betulinic acid on MepA efflux pump inhibition in Staphylococcus aureus: Antibacterial and molecular study	6
Reaction of 7α-bromo-6-nitrocholest-5-enes with hydrazine: Formation of steroidal pyrazolines and molecular docking against SARS-CoV-2 omicron protease	6
Design, synthesis and characterization of novel cholesterol derivatives: Anti-cancer activity, ADMET profiling and DFT insights	6
Metabolism of progestogens used for contraception and menopausal hormone therapy	6
Descriptive analysis of the relationship between progesterone and basal body temperature across the menstrual cycle	6
In vitro metabolic profiling of 6-chloro-testosterone and 6-ene-testosterone by liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-time of flight (GC-TOF) mass spectrometry	6
Synthesis and anticancer properties of a hybrid molecule with the testosterone and estradiol head-groups	6
Editorial Board	6
Editorial Board	6
Microbial catalyzed derivatization of canrenone with Glomerella fusarioides, and Cunninghamella blakesleeana, and evaluation of aromatase inhibitory activity of the resulting metabolites	6
Practical synthesis of chenodeoxycholic acid from phocaecholic acid	6
Current advances in phytosterol free forms and esters: Classification, biosynthesis, chemistry, and detection	5
The advancement of structure, bioactivity, mechanism, and synthesis of bufotalin	5
Sinulasterols D–G, four new antibacterial steroids from the South China sea soft coral Sinularia depressa	5
The isomers, aloe-emodin and emodin, possess differential inhibitory activities against CYP1B1 enzyme	5
Editorial Board	5
Bone mineral density, trabecular bone score and muscle strength in transgender men receiving testosterone therapy versus cisgender men	5
Comparison of a chemiluminescence immunoassay with LC–MS/MS in the determination of the plasma aldosterone concentration in patients with impaired renal function	5
A simple and efficient approach for the synthesis of cholesterol esters of long-chain saturated fatty acids by using Ph3P·SO3 as a versatile organocatalyst	5
Tricholosterols A–D, four new ergosterol derivatives from the mushroom Tricholoma terreum	5
Rodent models in polycystic ovarian syndrome: Dissecting reproductive and metabolic phenotypes for therapeutic advancements	5
Sudanese Toombak smokeless tobacco users harbour significantly altered long–term cortisol body production	5
MiR-221-5p/Smad3 axis in osteoclastogenesis and its function: Potential therapeutic target for osteoporosis	5
25-OH Vitamin D concentrations measured by LC-MS/MS are equivalent in serum and EDTA plasma	5
Protective effects of milk thistle (Sylibum marianum) seed oil and α-tocopherol against 7β-hydroxycholesterol-induced peroxisomal alterations in murine C2C12 myoblasts: Nutritional insights associated	5
Editorial Board	5
Editorial Board	5
Potential of betulinic acid in the Antiformation and eradication of bacterial biofilms and pharmacokinetic and toxicological analysis	5
Endocrine disruptors and arterial hypertension: A developing story	5
Therapeutic effects of Stemmoside C against Salmonella enterica serotype typhimurium infected BALB/c mice	5
The Effect of Vitamin D3 supplementation on Flunitrazepam-Induced testicular dysfunction in Wistar rats	5
Corticosteroids: A boon or bane for COVID-19 patients?	5
Structural and functional characterization of genes and enzymes involved in withanolide biosynthesis in Physalis alkekengi L.	5
Parisvaniosides A–E, five new steroidal saponins from Paris vaniotii	5
Invalidating betulinic acid as a potential inhibitor against the main protease of SARS-CoV-2 via combined approaches	5
Novel combination of multi-walled carbon nanotubes and gold nanocomposite for photothermal therapy in human breast cancer model	5
Advances in the understanding of androgen receptor structure and function and in the development of next-generation AR-targeted therapeutics	5
Editorial Board	5
Understanding the role of hormones in pediatric growth: Insights from a double-debiased machine learning approach	5
Effects of hypothyroidism on the female pancreas involve the regulation of estrogen receptors	5