OOIR: Observatory of International Research

Papers

(The TQCC of Steroids is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Ligand-based analysis of the antifungal potential of phytosterols and triterpenes isolated from Cryptostegia grandiflora against Candida auris FKBP12	48
Editorial Board	27
Retraction notice to “Thyroid hormone is a MAPK-dependent growth factor for thyroid cancer cells and is anti-apoptotic” [Steroids 72(2) 2007 180–187]	25
Membrane progesterone receptors on the cell membrane: A review highlighting potential export motifs in mPRα regulating its trafficking to the cell surface	25
Cortisol resistance in the degu (Octodon degus)	23
Isolation, structural elucidation of new phytoecdysteroids from Ajuga decumbens Thunb	22
Effects of estradiol, progesterone or cAMP on expression of PGRMC1 and progesterone receptor in a xenograft model of human endometrium and in endometrial cell culture	22
Synthesis of methotrexate-betulonic acid hybrids and evaluation of their effect on artificial and Caco-2 cell membranes	21
DG-8d, a novel diosgenin derivative, decreases the proliferation and induces the apoptosis of A549 cells by inhibiting the PI3k/Akt signaling pathway	20
Acute serum protein and cytokine response of single dose of prednisone in adult volunteers	19
Mitochondrial dysfunction and cardiac ischemia/reperfusion injury are attenuated by nandrolone: Role of JAK-STAT3 pathway	19
Nandrolone decanoate induced kidney injury through miRNA-146a targeting IRAK1 and TRAF6 via activation of the NF-κB pathway: The effect of moderate exercise	18
Functions of dehydroepiandrosterone in relation to breast cancer	17
The roles of methylprednisolone treatment in patients with COVID-19: A systematic review and meta-analysis	17
Acquired 11β-Hydroxylase deficiency in etomidate and (Iso)propoxate abusers: A nascent endocrine condition	16
17beta-estradiol alleviates contusion-induced skeletal muscle injury by decreasing oxidative stress via SIRT1/PGC-1α/Nrf2 pathway	15
Biotransformation of hydrocortisone succinate with whole cell cultures of Monascus purpureus and Cunninghamella echinulata	15
Ascorbic acid Mitigates behavioural disturbances associated with letrozole-induced PCOS via switching-off JAK2/STAT5 and JAK2/ERK1/2 pathways in rat hippocampus	14
Antitumor potential of novel 5α,6β-dibromo steroidal D-homo lactone	14
Target-specific high-throughput screening of anti-inflammatory phytosteroids for autoimmune diseases: A molecular docking-dynamics simulation approach	14
Steroid sulfatase in the mouse NIH-3T3 fibroblast cell line: Characterization, and downregulation by glucocorticoids	14
Unleashing the pharmacological potential of taste receptors in reproductive processes beyond their gustatory role	14
Synthesis and antitumor activity of some cholesterol-based selenocyanate compounds	14
The location of estrogen receptor variant ER-α36 is associated with the invasion of glioblastoma	14
Influence of synthetic isoflavones on selected urinary steroid biomarkers: Relevance to doping control	14

Editorial Board	14
An improved synthesis of azedarachol	13
Insight into isolation and elucidation of cytotoxic ergostanoids from the mushroom Sarcosphaera crassa (Santi) Pouzar: An edible mushroom	13
Epoxide of diosgenin acetate synthesis: DoE for diastereoselective yield optimization, antimicroibial, antioxidant and antiproliferative effects	13
Drugs possessing aryloxypropanamine pharmacophore, duloxetine, dapoxetine and propranolol, increase allopregnanolone in rat brain: Possible involvement of allopregnanolone in their central nervous sys	13
Synthesis, antifungal evaluation, and molecular docking studies of steroidal thiazolopyrimidines	13
Androgenic steroids in Over-the-Counter dietary Supplements: Analysis for association with adverse health effects	13
Synthesis and biological evaluation of novel steroidal pyrazole amides as highly potent anticancer agents	12
Systemic corticosteroid use and cardiovascular risk in patients hospitalized for pneumonia	12
Synthesis, anti-leukemia activity, and molecular docking of novel 3,16-androstenedione derivatives	12
Characterization and functional analysis of BmSR-B1 for phytosterol uptake	12
The effect of transdermal 17β-estradiol combined with norethisterone acetate treatment on the lipid profile in postmenopausal women: A meta-analysis and systematic review of randomized controlled tria	12
Theoretical study of the pyridyl-cholestane formation pathway using DFT: A stepwise mechanistic approach	12
Anticancer properties of caudatin and related C-21 steroidal glycosides from Cynanchum plants	12
Polycystic ovary syndrome: Insights into its prevalence, diagnosis, and management with special reference to gut microbial dysbiosis	12
Response to ‘25-OH Vitamin D concentrations measured by LC-MS/MS are equivalent in serum and EDTA plasma’	12
Editorial Board	12
A novel role of catalase in cholesterol uptake of Helicobacter pylori	11
Low and high doses of oxandrolone promote pathological cardiac remodeling in young male rats	11
Progestogens exhibit progestogen-, promoter- and isoform-specific effects via the progesterone receptor	11
Antibacterial activity of withanolides and their structure-activity relationship	11
TFA-mediated stereoselective aza-Michael addition for the synthesis of 3β-arylamine derivatives of withaferin A and evaluation of their anticancer potential	11
Glucocorticoid signaling and the impact of high-fat diet on adipogenesis in vivo	11
Androgen and glucocorticoid receptor phosphorylation following resistance exercise and pre-workout supplementation	11
Synthesis of hyocholic acid and its derivatization with sodium periodate to distinguish it from cholic acid by mass spectrometry	10
European Network for oxysterol research (ENOR): 10th ENOR symposium – Web meeting	10
Investigating the influence of estrous cycle-dependent hormonal changes on neurogenesis in adult mice	10
Genetic insights into vitamin D deficiency: a case-control study of GC and CYP24A1 gene polymorphism	10
The role of estrogen metabolites in human ovarian function	10
A simple but unusual rearrangement of an oleanane to a taraxerane-28,14 β -olide	9
Editorial Board	9
Synthesis and cytotoxicity of betulin and betulinic acid derived 30-oxo-amides	9
Editorial Board	9
Kuwanon C inhibits proliferation and induction of apoptosis via the intrinsic pathway in MDA-MB231 and T47D breast cancer cells	9
Editorial Board	9
Synthesis and characterization of epoxide impurities of abiraterone acetate	9
Filamin A in triple negative breast cancer	9
Triazole-estradiol analogs: A potential cancer therapeutic targeting ovarian and colorectal cancer	8
20-Hydroxyecdysone bioavailability and pharmacokinetics in Gerbillus tarabuli, a gerbil model for metabolic syndrome studies	8
Isosteroidal alkaloids from Fritillaria hupehensis Hsiao et K.C.Hsia: Synthesis and biological evaluation of alkaloid derivatives as potential cytotoxic agents	8
Editorial Board	8
Vecuronium bromide and its advanced intermediates: A crystallographic and spectroscopic study	8
Shatavarin-IV, a steroidal saponin from Asparagus racemosus, inhibits cell cycle progression and epithelial-to-mesenchymal transition in AGS cells under hyperglycemic conditions	8
Anti-cancer activity, and molecular docking of novel hybrid heterocyclic steroids revealed promising anti-hepatocellular carcinoma agent: Implication of cyclin dependent kinase-2 pathway	8
A hormonal side effect of anabolic steroids among a sample of Baghdad male bodybuilders	8
An association of VDR gene polymorphism in hypovitaminosis D mediated secondary hyperparathyroidism in adolescent girls; a tertiary hospital study in central India	8
Corrigendum to “Effects of neural-derived estradiol on actin polymerization and synaptic plasticity-related proteins in prefrontal and hippocampal cells of mice” [Steroids 177 (2022) 108935]	8
Estrogen signaling in healthy and tumor brain	8
Testosterone replacement has a beneficial effect on the hemostatic system by altered gene expression of coagulation factors	8
Synthesis and anti-inflammatory effects of Δ7-Cholestenol and Δ8(14)-Cholestenol derivatives	8

Evaluation of structural and thermodynamic insight of ERβ with DPN and derivatives through MMGBSA/MMPBSA methods	8
Dehydroepiandrosterone supplementation improves diminished ovarian reserve clinical and in silico studies	7
Editorial Board	7
Validation of a LC-MS/MS method for establishing reference intervals and assessing diagnostic performance of urinary free cortisol and cortisone	7
Mass spectrometric stochastic dynamic 3D structural analysis of mixture of steroids in solution – Experimental and theoretical study	7
Synthesis, NMR and X-ray characterization of dibenzoannulated dimeric steroid spiroketals. Evaluation of cytotoxicity and anti-inflammatory activity	7
Navigating nonalcoholic fatty liver disease (NAFLD): Exploring the roles of estrogens, pharmacological and medical interventions, and life style	7
A comprehensive update on phytochemistry, analytical aspects, medicinal attributes, specifications and stability of stigmasterol	7
Application of a fluorine strategy in the lead optimization of betulinic acid to the discovery of potent CD73 inhibitors	7
Navigating a plethora of progesterone receptors: Comments on the safety/risk of progesterone supplementation in women with a history of breast cancer or at high-risk for developing breast cancer	7
Expression of pregnenolone-synthesizing enzymes CYP11A1 and CYP1B1 in the human, rat, and mouse brain	7
BSS-4, a diosgenin analogue, reduces carrageenan-induced paw inflammation in rat	7
Editorial Board	7
Mifepristone’s effects on depression- and anxiety-like behavior in rodents	7
Synthesis of fully functionalized spirostanic 1,2,3-triazoles by the three component reaction of diosgenin azides with acetophenones and aryl aldehydes and their biological evaluation as antiprolifera	7
Microwave-assisted one-pot multicomponent synthesis of steroidal pyrido[2,3-d]pyrimidines and their possible implications in drug development	7
Sonogashira coupling-based synthesis and in vitro cytotoxic evaluation of C-2 alkynyl derivatives of withaferin A	7
Editorial Board	7
Steroids from the mushroom Ganoderma shandongense and their AChE inhibitory activities	7
Formation of nitrogen-containing six-membered heterocycles on steroidal ring system: A review	7
An overview on androgen-mediated actions in skeletal muscle and adipose tissue	7
An efficient regioconvergent synthesis of 3-aza-obeticholic acid	6
Rfamide-related peptide-3(RFRP-3) receptor gene is expressed in mouse ovarian granulosa cells: Potential role of RFRP-3 in steroidogenesis and apoptosis	6
The effect of vitamin D2 supplementation on vitamin D levels in humans: A time and dose–response meta-analysis of randomized controlled trials	6
Editorial Board	6
Synthesis and anticancer properties of a hybrid molecule with the testosterone and estradiol head-groups	6
The interpretation of immunometric, chromatographic and mass spectrometric data for steroids in diagnosis of endocrine disorders	6
Metabolism of progestogens used for contraception and menopausal hormone therapy	6
Anti-apoptotic effects of diosgenin on ovariectomized hearts	6
Effect of betulinic acid on MepA efflux pump inhibition in Staphylococcus aureus: Antibacterial and molecular study	6
Significance of vitamin D responsiveness on the etiology of vitamin D-related diseases	6
Practical synthesis of chenodeoxycholic acid from phocaecholic acid	6
Structures and functions of human placental aromatase and steroid sulfatase, two key enzymes in estrogen biosynthesis	6
Natural products derived steroids as potential anti-leishmanial agents; disease prevalence, underlying mechanisms and future perspectives	6
Descriptive analysis of the relationship between progesterone and basal body temperature across the menstrual cycle	6
Dexamethasone induces cancer mitigation and irreversible senescence in lung cancer cells via damaging cortical actin and sustained hyperphosphorylation of pRb	6
Editorial Board	6
The isomers, aloe-emodin and emodin, possess differential inhibitory activities against CYP1B1 enzyme	5
Understanding the role of hormones in pediatric growth: Insights from a double-debiased machine learning approach	5
Comparison of a chemiluminescence immunoassay with LC–MS/MS in the determination of the plasma aldosterone concentration in patients with impaired renal function	5
Corticosteroids: A boon or bane for COVID-19 patients?	5
Reaction of 7α-bromo-6-nitrocholest-5-enes with hydrazine: Formation of steroidal pyrazolines and molecular docking against SARS-CoV-2 omicron protease	5
Sudanese Toombak smokeless tobacco users harbour significantly altered long–term cortisol body production	5
Parisvaniosides A–E, five new steroidal saponins from Paris vaniotii	5
Cardiac steroid ouabain transcriptionally increases human leukocyte antigen DR expression on monocytes	5
Novel combination of multi-walled carbon nanotubes and gold nanocomposite for photothermal therapy in human breast cancer model	5
Protective effects of milk thistle (Sylibum marianum) seed oil and α-tocopherol against 7β-hydroxycholesterol-induced peroxisomal alterations in murine C2C12 myoblasts: Nutritional insights associated	5
A simple and efficient approach for the synthesis of cholesterol esters of long-chain saturated fatty acids by using Ph3P·SO3 as a versatile organocatalyst	5
Sinulasterols D–G, four new antibacterial steroids from the South China sea soft coral Sinularia depressa	5
Rodent models in polycystic ovarian syndrome: Dissecting reproductive and metabolic phenotypes for therapeutic advancements	5
Therapeutic effects of Stemmoside C against Salmonella enterica serotype typhimurium infected BALB/c mice	5
MiR-221-5p/Smad3 axis in osteoclastogenesis and its function: Potential therapeutic target for osteoporosis	5
Current advances in phytosterol free forms and esters: Classification, biosynthesis, chemistry, and detection	5
25-OH Vitamin D concentrations measured by LC-MS/MS are equivalent in serum and EDTA plasma	5
Bone mineral density, trabecular bone score and muscle strength in transgender men receiving testosterone therapy versus cisgender men	5
Structural and functional characterization of genes and enzymes involved in withanolide biosynthesis in Physalis alkekengi L.	5
Advances in the understanding of androgen receptor structure and function and in the development of next-generation AR-targeted therapeutics	5
Tricholosterols A–D, four new ergosterol derivatives from the mushroom Tricholoma terreum	5
Effects of hypothyroidism on the female pancreas involve the regulation of estrogen receptors	5
The advancement of structure, bioactivity, mechanism, and synthesis of bufotalin	5
Intramuscular sex steroid hormones are reduced after resistance training in postmenopausal women, but not affected by estrogen therapy	5
Editorial Board	5
Endocrine disruptors and arterial hypertension: A developing story	5