OOIR: Observatory of International Research

Papers

(The TQCC of Steroids is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
The effect of vitamin D2 supplementation on vitamin D levels in humans: A time and dose–response meta-analysis of randomized controlled trials	41
Comparing the efficacy of corticosteroids among patients with community-acquired pneumonia in the ICU versus non-ICU settings: A systematic review and meta-analysis	29
Potential targets of diosgenin for the treatment of oral squamous cell carcinoma and their bioinformatics and transcriptional profiling analyses	27
Retraction notice to “Thyroid hormone is a MAPK-dependent growth factor for thyroid cancer cells and is anti-apoptotic” [Steroids 72(2) 2007 180–187]	23
Ligand-based analysis of the antifungal potential of phytosterols and triterpenes isolated from Cryptostegia grandiflora against Candida auris FKBP12	22
Novel compound heterozygous CYP17A1 mutations identified in a family with two siblings affected by 17α-hydroxylase/17,20-lyase deficiency	21
Differential induction of C6 glioma apoptosis and autophagy by 3β-hydroxysteroid-indolamine conjugates	20
Anti-apoptotic effects of diosgenin on ovariectomized hearts	19
Editorial Board	18
Synthesis of fully functionalized spirostanic 1,2,3-triazoles by the three component reaction of diosgenin azides with acetophenones and aryl aldehydes and their biological evaluation as antiprolifera	18
Anabolic steroids in livestock production: Background and implications for chemical food safety	18
Fast signaling by glucocorticoids shapes neural representations of behaviors	16
Editorial Board	15
Diagnosis values of three-dimensional power Doppler ultrasonography in polycystic ovary syndrome and its relationship with serum sex hormone levels	15
Editorial Board	14
Pediatric reference intervals for Free Testosterone, 17-OH Progesterone, Androstenedione, and IGF-1 with chemiluminescence immunoassay	14
Metabolism of progestogens used for contraception and menopausal hormone therapy	14
Relationship of steroid sex hormones with female sexual dysfunction in female patients having urinary incontinence	14
Synthesis and characterization of a fluorescent steroid dimer linked through C-19 by a 1,4-Bis(phenylethynyl)phenylene fragment	14
Editorial Board	14
Antioxidant activity of novel diosgenin derivatives: Synthesis, biological evaluation, and in silico ADME prediction	13
Editorial Board	13
Membrane progesterone receptors on the cell membrane: A review highlighting potential export motifs in mPRα regulating its trafficking to the cell surface	13
Biotransformation of metenolone acetate and epiandrosterone by fungi and evaluation of resulting metabolites for aromatase inhibition	13
Development of a LC-MS/MS method to measure serum 3-sulfate and 3-glucuronide 25-hydroxyvitamin D3 metabolites; comparisons to unconjugated 25OHD in pregnancy and polycystic ovary syndrome	13

In vitro evaluation of ferutinin on proliferation and osteogenesis differentiation in human unrestricted Somatic stem cells	13
Editorial Board	12
Editorial Board	12
Editorial Board	12
Prednisone and ibuprofen conjugate Janus dendrimers and their anticancer activity	12
Editorial Board	12
Recent advances in chemical synthesis, biocatalysis, and biological evaluation of diosgenin derivatives – A review	11
Anti-cancer activity of Marsdenialongise A, a new C21 steroidal glycoside isolated from Marsdenia longipes W.T. Wang (Apocynaceae)	11
Synthesis, antiproliferative evaluation and in silico studies of a novel steroidal spiro morpholinone	11
Microwave-assisted one-pot multicomponent synthesis of steroidal pyrido[2,3-d]pyrimidines and their possible implications in drug development	11
Differential off-target glucocorticoid activity of progestins used in endocrine therapy	11
Synthesis of methotrexate-betulonic acid hybrids and evaluation of their effect on artificial and Caco-2 cell membranes	10
Effects of estradiol, progesterone or cAMP on expression of PGRMC1 and progesterone receptor in a xenograft model of human endometrium and in endometrial cell culture	10
Further evidence for blood-to-brain influx of unconjugated bile acids by passive diffusion: Determination of their brain-to-serum concentration ratios in rats by LC/MS/MS	10
Structures and functions of human placental aromatase and steroid sulfatase, two key enzymes in estrogen biosynthesis	10
Effect of chronic administration of 17β-estradiol on the vasopressor responses induced by the sympathetic nervous system in insulin resistance rats	10
Rfamide-related peptide-3(RFRP-3) receptor gene is expressed in mouse ovarian granulosa cells: Potential role of RFRP-3 in steroidogenesis and apoptosis	10
The effects of vitamin D on different types of cells	10
Anti-diabetic effects of fungal Ergosta-4, 6, 8(14), 22-tetraen-3-one from Pholiota adiposa	10
Navigating a plethora of progesterone receptors: Comments on the safety/risk of progesterone supplementation in women with a history of breast cancer or at high-risk for developing breast cancer	9
Expression of pregnenolone-synthesizing enzymes CYP11A1 and CYP1B1 in the human, rat, and mouse brain	9
Purinergic signaling influences the neuroinflammatory outcomes of a testosterone-derived synthetic in female rats: Resistance training protective effects on brain health	9
Molecular pharmacology of mineralocorticoid receptor antagonists: The role of co-regulators	9
Structural perspectives on the androgen receptor, the elusive shape-shifter	9
Ergostanes from the mushroom Trametes versicolor and their cancer cell inhibition: In vitro and in silico evaluation	9
Nandrolone decanoate induced kidney injury through miRNA-146a targeting IRAK1 and TRAF6 via activation of the NF-κB pathway: The effect of moderate exercise	9
Unveiling the therapeutic potential of plant steroid peimine: A study on apoptotic induction in MRMT-1 cell line-induced breast cancer in rats	9
Isolation, structural elucidation of new phytoecdysteroids from Ajuga decumbens Thunb	8
1α,25-hydroxyvitamin D/VDR suppresses stem-like properties of ovarian cancer cells by restraining nuclear translocation of β-catenin	8
Testicular induced corticosterone synthesis in male rats under fasting stress	8
Effect of 1,25(OH)2-vitamin D3 on decidualization of human endometrial stromal cells	8
DG-8d, a novel diosgenin derivative, decreases the proliferation and induces the apoptosis of A549 cells by inhibiting the PI3k/Akt signaling pathway	8
Microwave-enhanced synthesis of 26-amino-22-oxocholestanes and their cytotoxic activity	8
Synthesis of 16β-derivatives of 3-(2-bromoethyl)-estra-1,3,5(10)-trien-17β-ol as inhibitors of 17β-HSD1 and/or steroid sulfatase for the treatment of estrogen-dependent diseases	8
Acute serum protein and cytokine response of single dose of prednisone in adult volunteers	8
Cortisol resistance in the degu (Octodon degus)	8
Dexamethasone attenuates dry eye-induced pyroptosis by regulating the KCNQ1OT1/miR-214 cascade	8
Association between sex hormones and gout: An analysis of the UK Biobank cohort	8
Validation of a LC-MS/MS method for establishing reference intervals and assessing diagnostic performance of urinary free cortisol and cortisone	8
Functions of dehydroepiandrosterone in relation to breast cancer	8
Cardioprotective effects of S-equol, a soybean metabolite with estrogen activity, and role of the PI3K/Akt pathway in a male rat model of ischemic reperfusion	7
An efficient regioconvergent synthesis of 3-aza-obeticholic acid	7
Mass spectrometric stochastic dynamic 3D structural analysis of mixture of steroids in solution – Experimental and theoretical study	7
Natural products derived steroids as potential anti-leishmanial agents; disease prevalence, underlying mechanisms and future perspectives	7
In silico studies on the molecular interactions of steroid hormones and steroid hormone mimicking drugs in the androgen receptor binding cleft – Implications for prostate cancer treatment	7
An insight on 7- ketocholesterol mediated inflammation in atherosclerosis and potential therapeutics	7
Synthesis and cytotoxic evaluation of novel hybrid estrane heterocycles as chemotherapeutic anti-cancer agents	7
Synthesis of 13β- and 13α-epimers of 3-hydroxy-17-hydroxymethylestra-1,3,5(10)-triene and considerations on their hormonal and antiproliferative potency	7
A synthesis of a rationally designed inhibitor of cytochrome P450 8B1, a therapeutic target to treat obesity	7
Synthesis and biological activities of bicyclic pyridines integrated steroid hybrid	7

Practical and scalable synthesis of beclomethasone dipropionate	7
Palladium catalysed cross coupling reactions on 2,3-isoxazol-17α-ethynyltestosterone, their anti-cancer activity, molecular docking studies and ADMET analysis	7
Corrigendum to “Novel role of signal transducer and activator of transcription 3 as a progesterone receptor coactivator in breast cancer” [Steroids 76 (2011) 381–392]	7
The roles of methylprednisolone treatment in patients with COVID-19: A systematic review and meta-analysis	7
Sonogashira coupling-based synthesis and in vitro cytotoxic evaluation of C-2 alkynyl derivatives of withaferin A	7
Clomiphene citrate as a new modality in management of vaginal bleeding with depomedroxyprogesterone acetate (DMPA): A randomized controlled trial	7
Editorial Board	6
Editorial Board	6
Mitochondrial dysfunction and cardiac ischemia/reperfusion injury are attenuated by nandrolone: Role of JAK-STAT3 pathway	6
Effect of betulinic acid on MepA efflux pump inhibition in Staphylococcus aureus: Antibacterial and molecular study	6
Long-term exposure to high-concentration dexamethasone in the inner ear via intratympanic administration	6
Steroid hormone-mediated regulation of sexual and aggressive behaviour by non-genomic signalling	6
An improved synthesis of azedarachol	6
Editorial Board	6
Uphill running preferred over downhill running for recovery from glucocorticoid-induced muscle atrophy	6
The anti-androgenic effect of quercetin on hyperandrogenism and ovarian dysfunction induced in a dehydroepiandrosterone rat model of polycystic ovary syndrome	6
Assessment of estrogen exposure from transdermal estradiol gel therapy with a dried urine assay	6
Editorial Board	6
Epoxide of diosgenin acetate synthesis: DoE for diastereoselective yield optimization, antimicroibial, antioxidant and antiproliferative effects	6
Reductive desymmetrization of steroid dimers	6
Editorial Board	6
Variability and quantification of serum medroxyprogesterone acetate levels	6
Editorial Board	6
Synthesis and anticancer properties of a hybrid molecule with the testosterone and estradiol head-groups	6
Editorial Board	6
Androgenic steroids in Over-the-Counter dietary Supplements: Analysis for association with adverse health effects	6
Synthesis and antitumor activity of some cholesterol-based selenocyanate compounds	6
Dexamethasone induces cancer mitigation and irreversible senescence in lung cancer cells via damaging cortical actin and sustained hyperphosphorylation of pRb	5
Improved synthesis and characterization of bile acid esters: Organogelation and supramolecular properties	5
Editorial Board	5
17β-Estradiol alleviates cardiac aging induced by d-galactose by downregulating the methylation of autophagy-related genes	5
Genomic signaling of vitamin D	5
A review of metabolic and microbial influences on women with polycystic ovarian syndrome	5
Steroidal alkaloids and their glycosides from the bulbs of Fritillaria unibracteata	5
MiR-221-5p/Smad3 axis in osteoclastogenesis and its function: Potential therapeutic target for osteoporosis	5
Validity of the association between five steroid hormones quantification and female infertility conditions: A new perspective for clinical diagnosis	5
Corticosterone rapidly reduces glutamatergic but not GABAergic transmission in the infralimbic prefrontal cortex of male mice	5
Global effects of pharmacologic inhibition of OSBP in human umbilical vein endothelial cells	5
Significance of vitamin D responsiveness on the etiology of vitamin D-related diseases	5
Synthesis, in vitro cytotoxic activity and molecular docking study of androstene and estrone derivatives	5
The effect of dehydroepiandrosterone (DHEA) supplementation on estradiol levels in women: A dose-response and meta-analysis of randomized clinical trials	5
Biotransformation of hydrocortisone succinate with whole cell cultures of Monascus purpureus and Cunninghamella echinulata	5
17beta-estradiol alleviates contusion-induced skeletal muscle injury by decreasing oxidative stress via SIRT1/PGC-1α/Nrf2 pathway	5
Editorial Board	5
High-intensity interval and moderate-intensity continuous training ameliorate the deteriorating acute effect of noise stress on corticosterone and testosterone in rats	5
Influence of synthetic isoflavones on selected urinary steroid biomarkers: Relevance to doping control	5
Phoenix dactylifera L. date tree pollen fertility effects on female rats in relation to its UPLC-MS profile via a biochemometric approach	5
A sustainable approach towards extraction of diosgenin from fenugreek seeds using polystyrene/divinyl benzene resin	5
Descriptive analysis of the relationship between progesterone and basal body temperature across the menstrual cycle	5
Effects of neural-derived estradiol on actin polymerization and synaptic plasticity-related proteins in prefrontal and hippocampal cells of mice	5