Tetrahedron Letters

Papers
(The median citation count of Tetrahedron Letters is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Reactivity-based detection of nitrite ion: Rapid colorimetric and fluorometric response down to nM level93
Concise synthesis of pyridopyridazines56
N-cyano-N-phenyl-p-toluenesulfonamide as electrophilic nitrile source for the synthesis of oxadiazoles53
Contents continued38
Tin(II)-chloride (SnCl2) mediated reduction of α,β-alkynyl carbonyl compounds25
Graphical abstract TOC23
Photochemical direct C3 cyanoalkylation of quinoxalin-2(1H)-ones with cyclobutanone oxime esters under catalyst-free conditions23
Editorial Board21
Transition-Metal-free Michael Addition/Denitrative cyclization of 2′-Nitrochalcones and thioacetamides for the synthesis of thioflavanones20
Manganese-catalyzed aerobic cross-dehydrogenative coupling of thiols with P(O)H compounds19
Decoration of GW9662 scaffold with a fragment-like hit via copper-catalyzed azide-alkyne cycloaddition reaction into peroxisome proliferator-activated receptor γ agonists19
I2/CAN as an efficient reagent for the direct oxidation of tertiary Csp3-H to Csp3-OH: Synthesis of bis(N-methyl-7-azaindol-3-yl) (phenyl) methanol from 3,3′-(phenyl methylene)-bis(N-methyl-7-azaindol18
Catalyst-free direct ring-opening of cyclic aldimines with aliphatic primary amines to construct o-hydroxy schiff bases18
New 8,17-epoxybriaranes from octocoral Briareum stechei (Kükenthal, 1908)18
Thermally generated bromine “Cation Pool-”mediated oxidation of indole to 2-oxindole17
Synthesis of sulfur-containing polybromoindoles from the marine alga Laurencia brongniartii17
Convenient synthesis of 6-Amino-2-naphthol by Copper-catalyzed Ullmann reaction17
Synthesis of Poly-substituted 2-Hydroxycyclobutanones via Norrish–Yang Photocyclization/1,2-Methyl Migration: Scope and limitations16
[Bis(trifluoroacetoxy)iodo]benzene mediated regioselectivec(sp2)–H selenylation of α-oxo ketene dithioacetals under ambient conditions15
Design and synthesis of naphthalimide-based CO fluorescent probes realizing tricolor detection and turn-on/off response15
Diverse ent-kaurane diterpenoids from Isodon henryi15
Design, synthesis and biological evaluation of difluoroalkylated protoilludanes obtained by a practical radical cascade difluoroalkylation-cyclization reaction14
Substrate-controlled selective acylation of quinazolinones: Access to 2-benzamido-N-formylbenzamides and 3-benzoylquinazolinones14
Synthesis of the 5/6 fused-spiro tricyclic framework of manginoid A14
Preparation of β-hydroxyketones (aldols) from the alkylation of O-silyl aryl cyanohydrins with epoxides14
Asymmetric synthesis of pyrrolo[2,3–b]indole scaffolds by organocatalytic [3 + 2] dearomative annulation14
Briavioid D, a rare 7β,8β-epoxybriarane from Briareum violaceum14
Editorial Board14
Facile and improved synthesis of the 2-O-β-d-glucopyranosyl-l-ascorbic acid14
Carboranes meet photochemistry: Recent progresses in light-mediated cage functionalisation14
Palladium-catalyzed regioselective arylation of 7-hydroxyflavone with diaryliodonium salts13
A new simple fluorescent probe for imaging endogenous hydrogen peroxide in RAW 264.7 cells13
CuCl-mediated desulfurization reactions of Dithiocarbamate Triethylamine salts: Access to 2-Aminooxazolines and Thioureas, and their synthetic applications13
A robust method using reducing inorganic salts for preventing the desulfurization of phosphorothioate oligonucleotides during the cleavage and deprotection step13
Alternate end-game strategies towards Nirmatrelvir synthesis: Defining a continuous flow process for the preparation of an anti-COVID drug13
Synthesis of substituted benzoates using a rhodium-mediated Hopf cyclization of 1,3-dien-5-ynes accessed from 2-pyrones13
Graphical abstract TOC13
Greener synthesis of Pyrroloacridine-1(2H)-one and 1,8-Dioxodecahydroacridine derivatives: Ascorbic acid mediated OrganocatalyticApproach13
Microwave assisted rapid synthesis of bicyclo aza-sulfone derivatives from aldehydes via aldoxime formation followed by Michael addition-1,3-dipolar cycloaddition with divinyl sulfone in one-pot12
Disulfides as sulfonylation reagents for the synthesis of sulfonated spiro[5.5]trienones under metal free conditions12
Synthesis of 1,3‑dicarbonyl compounds bearing hetero-substituted α-quaternary carbon via Fe(II)-catalyzed alkylation with alkylsilyl peroxides12
Visible light-induced 3H-indole hydrogenation using tetramethylethene as an inert hydrogen source12
An interesting fluorescent probe with aggregation-induced emission for highly sensitive and selective detection of Hg2+12
A sustainable approach to microwave assisted synthesis of 2-(het)/arylquinazolin-4(3H)-ones via ionic liquid supported Cu(II) catalyst12
Recent progress in chemistry of non-benzenoid carbohelicenes12
A near-infrared self-assembled micellar nanoprobe for highly selective detection of hydrazine12
The application and development of cyanating reagents in asymmetric cyanation reactions11
Faster and greener parallel chemical reaction work-up using ‘sponge’ extraction11
Graphical abstract TOC11
Peptide oxo-esters for ligation of peptide hydrazide at Gln and Asn sites11
Computational examination of a proposed highly-strained natural product11
Graphical abstract TOC11
Organocatalytic Mannich type reactions of glyoxylate imines and related compounds11
Graphical abstract TOC11
Graphical abstract TOC continued11
Graphical abstract TOC continued11
Graphical abstract TOC11
Vicinal diphosphorylation of enaminones with diaryl phosphine oxides via AlCl3-mediated C N bond cleavage11
Rh(III)-catalyzed C(sp2) H arylation and esterification cascade reaction of aryl acids with organic boronates11
Development of a cationic aggregate induced emission fluorescent probe for detection of aromatase11
2-(Hydroxypropan-2-yl)diphenylphosphine oxide (HDPO): A convenient precursor to diphenylphosphine oxide (DPO)11
Graphical abstract TOC11
Graphical Abstract TOC Continued.11
Graphical abstract TOC11
I2–DMSO-mediated formal [3 + 1 + 2] synthesis of pyrimido[1,2-b]indazole using 1,4-dithiane-2,5-diol as a surrogate of ethylene11
Graphical abstract TOC10
Total synthesis of merodesmosine10
Graphical abstract TOC10
Synthesis and studies on the photophysical/biophysical properties of triazolylfluorene-labeled 2′-deoxyuridines10
Kinetic and thermodynamic concepts as synthetic tools in supramolecular chemistry for preparing macrocycles and molecular cages10
Cyclocondensation of o-aminophenols with α-ketothioesters in acidic media: A facile synthesis of 2-acylbenzoxazoles10
Visible light-mediated C H sulfinylalkylation of N-heteroaromatics via dimethyl sulfoxide10
New tetracyclic and pentacyclic isomalabaricanes from the marine sponge Rhabdastrella globostellata (Carter, 1883)10
The first enantioselective total synthesis of the eremophilane-type sesquiterpenoid (−)-peniroqueforin C10
Palladium catalyzed amidation of phenyl carboxylates and anilines using aqueous micellar catalysis10
Graphical Abstract TOC Continued10
Approach to α-fluorinatedacetoxy ketones by fluoroacetoxylation of alkynes with hyper-valent iodine(III) reagents10
Catalyst identification for chemoselective phosphorylation of phenols and aliphatic alcohols10
Palladium-catalyzed borylation of aryl bromides and chlorides using phosphatrioxa-adamantane ligands10
Rhenium-catalyzed disproportionation of allylic alcohols and selective reduction of allylic alcohol with secondary alcohol10
I2 and aqueous TBHP induced aerial oxidative coupling of 2-aminobenzyl alcohols and nitriles: A novel metal-free route towards quinazolines synthesis10
A divergent approach to synthesize C7 epoxyquinones from (–)-shikimic acid10
Synthesis of spiro[piperidine-4,3′-pyrrolo[3,4-c]quinolines via 1,3-dipolar cycloaddition of azomethine ylides and 3-Nitro-2(1H)-quinolones10
Highly effective one pot reaction from α-hydrazonoesters to give anilinoesters via α-diazoesters10
Visible-light-promoted trifluoromethylation/arylation of unactivated alkenes with Togni-CF3 for the synthesis of trifluoromethylated pyrrolo[1,2–a]indoles10
DFT study on mechanism of nickel-catalyzed decarbonylative reductive alkylation of aroyl fluorides with alkyl bromides10
Reaction of 3-Br-coumalate with alkynals10
Graphical abstract TOC10
1,4,2-Diazaborole-type heterocycle from 2H-azirine-2-carboxylate and [(alkylamino)methyl]trifluoroborate10
Recent advances in development of bibenzo[c]thiophene derivatives for application in functional materials10
Graphical abstract TOC10
N,N'-Disulfonylhydrazines: A novel source of sulfonyl moieties for synthesis of diaryl sulfones10
2-Guanidinoethanesulfonyl sesquiterpenes from the marine sponge Agelas nakamurai10
Copper-catalyzed radical cascade cyclization of 2-(allyloxy)arylaldehydes towards chroman-4-one derivatives10
Synthesis of tetrahydropyrans via an intermolecular oxa-michael/michael stepwise cycloaddition10
Visible light-promoted alkylation of electron-deficient alkenes with alkylsilyl peroxides9
Chiral phosphoric acid-catalyzed reaction between C-alkynyl imine precursor and thiol: Access to highly enantioenriched alkynyl isoindolinones with N,S-ketal framework9
Dipyridylamine-acetamide (Dpaa): A primary amine protecting group orthogonally cleavable under acidic conditions in the presence of t-butyloxycarbonyl (Boc) and t-butylester9
Graphical abstract TOC9
Development of 1,3a,6a-triazapentalene derivatives as practical erasable fluorescent cell staining reagents9
Concise synthesis of (±)-gomadalactone A9
Synthesis of spiroisoxazoline oxindoles by base-promoted annulation of oxime esters and isatins9
B(C6F5)3-catalyzed regio- and stereoselective cyanation of isatogens and their derivatives9
Synthesis of neodesmosine-d4 and quantitative LC-MS/MS analysis of neodesmosine in biological samples9
Synthesis of polysubstituted naphthalenes from cyclopentadienones using o-diiodobenzene/NaH as a benzyne system9
Visible light-induced pericyclic cascade reaction for the synthesis of eight-membered rings9
Thiobenzoic acid–catalyzed radical–radical cross–coupling between benzyl alcohols and benzophenones via hydrogen atom transfer9
Brønsted acid-catalyzed selective alkylation of tetrazoles with acetone9
Photoredox-catalyzed cross-coupling of N-indolylacetic acids with nitrones: Access to indole-N-ethylamines9
(+)/(−)-Alexanoid A, a pair of enantiomeric sesquiterpenoid with a novel 5/6/6 tricyclic backbone from the stem of Syringa pinnatifolia9
Silver-catalyzed cross-dehydrogenative coupling of benzoxazine-2-ones with resorcinol9
Asymmetric total synthesis of Sumatranin A9
Synthesis of quinazolinone derivatives with a seven‐membered ring using borrowing hydrogen methodology9
Graphical abstract TOC9
A concise synthesis of (-)-dihydrospirotryprostatin B via tandem Michael addition9
Blue light induced [2,3]-sigmatropic rearrangement reactions of tosylhydrazones9
Trimethyl borate assisted chemoselective synthesis 1,5-dihydrodiazepines from hemicurcuminoids and o-phenylenediamines9
Visible light-activated ruthenium-catalysed direct arylation at ambient temperature9
Graphical abstract TOC9
GRAPHICAL ABSTRACT TOC continued9
Mercaptan-free approach to the synthesis of Ethiprole, an insecticide9
Efficient access to multi-substituted 1-aminoisoquinolines via Rh(III)-catalyzed oxidative annulation of aminopyridine pivalamides with internal alkynes9
An efficient and convenient reaction system based on MnAl layered double oxide for the aerobic oxidation of alkylarenes9
Tandem Prins bicyclization for the synthesis of tetrahydropyran containing spirocompounds9
Visible-light-induced trifluoromethylation/cyclization of unactivated alkenes: Synthesis of CF3-substituted fused tricyclic indoles9
Visible-light-promoted sodium iodide-mediated sulfenylation of imidazo[1,2-a]pyridines heterocycle using thiosulfate as odorless electrophilic arylsulphenyl source8
24-Dehydrohippuristanol, a cytotoxic spiroketal steroid from Isis hippuris8
Reactivity insights from the allylation of substituted phenols with 2-allyloxy-1-methylpyridinium triflate8
Synthesis of π-extended aza[5]helicene bearing AuI-acetylide at the outside or the inside of the helix8
Synthesis of bacteriochlorophyll-c analogs possessing thio-functionalized substituents at the 20-position and their self-aggregation8
Nitration of deactivated aromatic compounds using Lithium nitrate8
Synthesis of 1,3-benzooxazine spirosuccinimides through the cascade reaction of 2-phenoxy-1H-benzo[d]imidazoles with maleimides8
One pot synthesis of carboxylic acid, ester, and amide derivatives from iodoarenes in aqueous solubilized systems using sodium oleate as surfactant at room temperature8
Towards the total synthesis of aleurodiscal8
Contents continued8
Graphical abstract TOC continued8
A turn-on fluorescent probe for palladium(II) detection with a large Stokes shift and lysosomes-targeting ability8
Elemental sulfur promoted condensation of indoles and 1,2-phenylenediamines8
Simple, green and one pot new strategy for synthesis of the phthalimide derivatives8
A convenient ammonium chloride facilitated mild and efficient synthesis of Benzazepinoindole derivatives through a Pictet-Spengler reaction*8
Methodologies for the synthesis of 3,4-ethylenedithiothiophene (EDTT) and its derivatives for use as semiconductor materials8
Editorial Board8
Electrochemical synthesis of 1,2,3-trisubstituted pyrroles from β-dicarbonyl compounds, aldehydes and amines via radical addition reaction8
First total synthesis of aspergillolide8
Graphical abstract TOC8
Aerobic copper-catalyzed homo-coupling of azaallyl anions: A facile access to vicinal diamines8
Copper(I) bromide-mediated C(sp2)-H direct sulfonylation of tertiary enamides for synthesis of (E)-β-amidovinyl sulfones8
Graphical abstract TOC8
Graphical abstract TOC continued8
Facile access to sodium arylsulfinates via nucleophilic C S bond cleavage of 2-(arylsulfonyl)pyrimidines8
Stable planar chirality of arylated pillar[6]arene and its thermal response8
Efficient total synthesis of three alpinoids via the Au(I)-catalyzed Meyer-Schuster rearrangement8
Erratum to “Efficient thiocyanation of aromatic compounds using NH4SCN, DMSO and H2SO4” [Tetrahedron Lett. 101C (2022) 153929]8
Silver-catalyzed regioselective synthesis of (E)-vinyl sulfones from nitroolefins and thiophenols8
Development of a simple and safe route to C-3 arylated 1H-pyrazoles8
Effect of additives on the asymmetric reduction of fluorinated ketones using cyanobacterium Synechocystis sp. PCC 68038
Iron-catalyzed one-pot tandem oxidation/acylation/dearomatization of biaryl ynones with benzyl alcohols: access to diversified acylated spiro[5.5]trienones8
Studies towards DIAD promoted N-demethylation of N,N-dimethylanilines8
Pentafluorophenol (C6F5OH) catalyzed Regioselective annulation for the synthesis of tetracyclic Dihydrochromeno indoles8
Applications of phenalenyl-based Cu(II) complex towards direct oxidation of aldehydes to esters8
Synthesis of (1Z)-deacylcnicin8
Graphical abstract TOC8
Spiroindimicin model studies reveal a facile route to cyclopenta[c]pyrazoles7
Synthesis and antifungal activity of polyalthic acid-1,2,3-triazole-arylsulfonamide derivatives7
Synthesis of quinoline fused 1,2,3-triazole derivatives via continuous CuAAC and C H arylation; anti-breast cancer, anti-EGFR and HER2 activities, computational studies7
Organoborane-catalyzed selective 1,2-reduction of alkynones with hydride transfer: Synthesis of benzyl alkynes7
Homogeneous organic reductant based on 4,4′- Bu2-2,2′-bipyridine for cross-electrophile coupling7
CuBr2 catalyzed alkynylation of tertiary methylamine with terminal alkyne using aqueous TBHP under mild conditions7
A copper catalyzed Doyle–Kirmse reaction for the concise and effective preparation of multifunctional 3-allyl-3-(thio) succinimides7
Facile synthetic route to isoxazoles from β-sulfinyl- and β-sulfonyl-cyclohexenones via regioselective nitrile oxide cycloaddition and in-situ elimination7
Copper-catalyzed γ-selective yne-allylic substitution of vinyl ethynylethylene carbonates towards a formal [3 + 3] cycloaddition7
Graphical abstract TOC7
Electrochemical-induced radical allylation via the fragmentation of alkyl 1,4-dihydropyridines7
Iodotriphenylphosphonium iodide mediated deprotection of aryl alkyl ethers under metal-free and neutral conditions7
Bioactivity of pyridine and isoquinoline homodimers7
Cynotofuranoside A-C: Uncommon C21-steroidal furanosides derived from the acid hydrolysate of Cynanchum otophyllum roots7
Editorial Board7
Synthesis of carbacycloisodityrosine, an analogue of cycloisodityrosine in antitumor bicyclic hexapeptide RA-VII7
Graphical abstract TOC7
A concise approach for the synthesis of the tetracyclic framework of Lycibarbarines A and B7
On the protonation and deuteration of 2-methylmercaptothiophene: Formation of a 2′,3′-dihydro-2,3′-bithiophene dimer7
Graphical abstract TOC7
Multicomponent reaction between (Z)-chloroximes, isocyanides and NH-heterocyclic rings7
Editorial Board7
Merging Halogen-Atom transfer with transition metal catalysis7
Photocatalytic annulative trifluoromethyletherification of 1,6-enynes for accessing 1-indanones7
Implementation of Zincke reaction in one-pot synthesis of switchable, Ag+ and Hg2+ sensing aza-merocyanines based on α-aminopyridin-3,5-dicarbonitrile moiety7
Ag(I)-catalyzed synthesis of (E)-alkenyl phosphonates by oxidative coupling of H-phosphites with β-nitroolefins7
Biosynthesis of fusicoccane-type diterpenoids featuring a 5–8–5 tricyclic carbon skeleton7
Mukaiyama reagent: An efficient reaction mediator for rapid synthesis of 1,2-disubstituted-1H-benzo[d]imidazoles7
Metal- and solvent-free synthesis of 2-benzyl-3-arylquinoline using a pseudo-three-component reaction7
Editorial Board7
Efficient access to spiro[quinazoline-thiophen](thi)ones via acetic acid mediated [3 + 2] annulation of quinazolin(thi)one enamines with dithianediol7
Recent advances in site-selective C H functionalization of naphthalenes: An update 2020–20247
Teuchamaedol A, a new neo-clerodane diterpenoid from the aerial parts of Teucrium chamaedrys7
Electrochemical synthesis of 2,5-disubstituted-1,3,4-thiadiazoles via oxidative cyclization of benzothiohydrazides and aldehydes catalyzed by tetra-n-butylammonium iodide7
Graphical abstract TOC continued7
Editorial Board7
Contents continued7
Iron-catalyzed intramolecular reductive cyclization of o-nitroarenes to indoles under visible light irradiation7
Formation of triarylphosphines via P H/C F cross coupling reactions catalyzed by nickel7
Electrochemical oxythiocyanation of ortho-olefinic amides: Access to diverse thiocyanated benzoxazines7
Synthesis and cytotoxicity evaluation of retro-inverso analogue of antitumor bicyclic hexapeptide RA-VII7
Synthesis of 1,3-thiazolidine-2-thiones using CS2 and epoxy amines7
Metal-free, visible-light-induced C(sp2)-H functionalization/C O bond formation for the synthesis of flavones using air as an oxidant7
PPh3-catalyzed chemoselective reduction of aldehydes to alcohols7
Access to α,α-dihaloacetophenones through anodic C C bond cleavage in enaminones7
New conjugated 2,6-carbazolylazulenes with intense absorption and emission in the visible spectrum7
The ferrocenylation reaction of olefins and alkynes with a novel ferrocenyl sulfonium salt based on thianthrene skeleton7
Rearranged and enantiomeric alkaloids from Cephalotaxus sinensis7
Editorial Board7
Oxidative [3 + 2] cycloaddition of triazenes and trisubstituted dichloroalkenes7
Synthesis of Phenanthridine derivatives from Arynes and Ketimines via aza-Diels-Alder/decarboxylation reactions7
Graphical abstract TOC7
Graphical abstract TOC7
Continuous flow synthesis of C-acyloxy-substituted aziridines in microchannel reactor: Addition of carboxylic acids to 2-methylenaziridines7
Editorial Board7
Synthesis of 3‑alkyl and 1,3-Bis(alkyl)indolizine amides from α-bromohydroxamates6
An undescribed chromene glucoside from the endophytic Paracylindrocarpon sp. KMU22201 associated with Delphinium yunnanense6
A DDQ-mediated ring-opening and aromatization cascade of a tetrahydrocarbazole-fused tetrahydrofuran for the synthesis of olivacine6
Merosesquiterpenes from the marine sponge Spongia pertusa Esper and their antifungal activities6
Halogenated pyridine derivatives from cycloaddition/cycloreversion of oxazinone and haloalkyne precursors6
Organocatalysis and organic electrosynthesis as an alternative for zingerone preparation6
Radical 4-exo cyclization of bicyclo[2.2.2]octene derivatives: Construction of tricyclo[3.3.1.02,7]nonane skeleton6
S-Benzyl-N,N'-diphenyl substituted isothiouronium iodide as a highly efficient organocatalyst for transfer hydrogenation of 2-substituted quinolines6
Synthesis of a new CTX derivative with naphthalene units6
Graphical abstract TOC6
Lipase-catalyzed allyloxycarbonylation of alcohols using allyl phenyl carbonate6
Total synthesis of halogenated spirocyclic polyketide (±)-actinospirol A6
Direct substitution of the hydroxy group of alcohols with N-nucleophiles mediated by the substoichiometric amount of Selectfluor™ F-TEDA-BF as a precatalyst under mild reaction conditions6
Application of multi-wall carbon nanotubes supported l-proline in continuous flow catalysis6
HFIP-promoted one-pot synthesis of (Pyrazolo[1,5-a]pyrimidinyl)(indolyl)methanes using Rongalite as a C1 synthon under mild conditions6
Direct synthesis and optical absorbance studies of the first representatives of 3-ylidenemalononitrile derivatives of 2-oxopyrroles containing a phenol moiety6
Continuous flow photooxidation of alkyl benzenes using fine bubbles for mass transfer enhancement6
Development of polymer-immobilised acridinium catalyst and its application in photoinduced 1,4-addition to α,β-unsaturated carbonyl compounds6
A simple and efficient fluorescent probe based on 1,8-naphthalimide – Ebselen for selectively detecting H2S in living cells6
Contents Continued6
Hydrosilylation of ketones catalyzed by novel four-coordinate copper(I) complexes under mild conditions6
Asymmetric hydrogenation of boron-substituted olefin, enamine, and imine derivatives6
Gram-scale preparation of DAMGO by typical solid phase synthesis6
Graphical Abstract TOC Continued6
Synthesis of the 3′-terminal dinucleotide of tRNA aminoacylated with the unnatural ω-thioaspartic acid6
Copper-catalyzed enantioselective 1,4-hydroboration of α,β-unsaturated amides6
Synthesis of functionalized cyclopropanes from alkyl pinacol boronates by a radical polar cyclization cascade6
Efficient synthesis of cytidine diphosphate diacylglycerol: A crucial precursor of glycerophospholipids biosynthesis6
Metal-free synthetic approaches to 1,5-disubstituted 1,2,3-triazoles6
Visible-light-induced dual C H functionalization of biaryl ynones via a 6-exo-trig domino radical addition/cyclization/dearomatization: Efficient access to alkylated spiro[5.5] trienones6
Cu3TiO4 nanoparticles catalyzed synthesis of N-alkylated SpiroQuinazolines: Blue LED activation and bioactivity evaluation6
Aggregation-induced emission fluorogenic probes for wash-free imaging of lipid droplets in living cells6
Dimroth rearrangements and its applications – Advancements over the past demi-decade6
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