OOIR: Observatory of International Research

Papers

(The H4-Index of Mechanisms of Ageing and Development is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Characterization of a natural model of adult mice with different rate of aging	144
Polypharmacy is differentially associated with 20-year mortality among community-dwelling elderly women and men: The Israel Glucose Intolerance, Obesity and Hypertension cohort study	102
Characteristics of geriatric rehabilitation inpatients based on their frailty severity and change in frailty severity during admission: RESORT	95
Insights into targeting cellular senescence with senolytic therapy: The journey from preclinical trials to clinical practice	92
Redox modulation of stress resilience by Crocus sativus L. for potential neuroprotective and anti-neuroinflammatory applications in brain disorders: From molecular basis to therapy	88
Phenolic acid metabolites of polyphenols act as inductors for hormesis in C. elegans	78
Effects of exosomal miRNAs in the diagnosis and treatment of Alzheimer’s disease	77
The role of cytokines/chemokines in an aging skin immune microenvironment	69
Impact of age and gender on glioblastoma onset, progression, and management	68
REDD1 knockdown ameliorates endothelial cell senescence through repressing TXNIP-mediated oxidative stress	68
Coenzyme Q10 supplementation – In ageing and disease	67
Brain aging mechanisms with mechanical manifestations	61
Strategies for late phase preclinical and early clinical trials of senolytics	59
Mitochondrial microRNAs (mitomiRs) in human ageing and diseases	56
Editorial Board	54
Sex differences in neuroimmunoendocrine communication. Involvement on longevity	52
Mosaic loss of Y chromosome and the association to mortality in Danish men aged 56–100 years	51
Age-related alterations and senescence of mesenchymal stromal cells: Implications for regenerative treatments of bones and joints	51
In reviewing the emerging biomarkers of human inflammatory bowel disease (IBD): Endothelial progenitor cells (EPC) and their vesicles as potential biomarkers of cardiovascular manifestations and targe	51
The role of mitochondria in cytokine and chemokine signalling during ageing	48
Molecular mechanisms and potential interventions during aging-associated sarcopenia	43
B cells from old mice induce the generation of inflammatory T cells through metabolic pathways	39
Effect of a lifestyle intervention on telomere length: A systematic review and meta-analysis	38
Klotho ameliorates angiotension-II-induced endothelial senescence via restoration of autophagy by inhibiting Wnt3a/GSK-3β/mTOR signaling: A potential mechanism involved in prognostic performance of Kl	38
Cyr61 promotes D-gal-induced aging C2C12 cell fibrosis by modulating Wnt/β-catenin signaling pathways	37

Senescence of skeletal stem cells and their contribution to age-related bone loss	37
Recent advances in the discovery of senolytics	37
Vascular participation in bone healing: Implications related to advancing age and morbidity	36
Piezo1 transforms mechanical stress into pro senescence signals and promotes osteoarthritis severity	36
Decreased oxidative stress response and oxidant detoxification of skin during aging	35
Editorial Board	35
Living in endemic area for infectious diseases accelerates epigenetic age	32