OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Biochemistry is 21. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
The Role of DEAD-Box ATPases in Gene Expression and the Regulation of RNA–Protein Condensates	343
Lipid Dynamics at Membrane Contact Sites	193
Emerging Approaches for Studying Lipid Dynamics, Metabolism, and Interactions in Cells	146
The Initiation of Eukaryotic DNA Replication	137
Moonlighting Enzymes at the Interface Between Metabolism and Epigenetics	114
DNA Damage and Replication Stress Checkpoints	105
The Purinosome: A Case Study for a Mammalian Metabolon	100
The Structural Dynamics of Translation	97
Mitochondrial DNA Release in Innate Immune Signaling	95
Mechanisms of General Anesthesia	86
The Inseparable Relationship Between Cholesterol and Hedgehog Signaling	82
Signaling from RAS to RAF: The Molecules and Their Mechanisms	81
High-Resolution Single-Molecule Magnetic Tweezers	73
Emerging Chemical Diversity and Potential Applications of Enzymes in the DMSO Reductase Superfamily	73
mRNA Regulation by RNA Modifications	72
Eukaryotic Ribosome Assembly	64
DNA–Protein Crosslinks and Their Resolution	63
Topoisomerase Regulation of Cancer Gene Expression	56
Validating Small Molecule Chemical Probes for Biological Discovery	52
Membrane Protein Complexity Revealed Through Native Mass Spectrometry	51
The Nicotinic Acetylcholine Receptor and Its Pentameric Homologs: Toward an Allosteric Mechanism of Signal Transduction at the Atomic Level	50
Essential Biology of Lipid Droplets	49
Structural Biochemistry of Muscle Contraction	47
	47
Influence of Nonspecific Interactions on Protein Associations: Implications for Biochemistry In Vivo	46

Natural and Engineered Guide RNA–Directed Transposition with CRISPR-Associated Tn7-Like Transposons	46
Ribonucleotide Incorporation by Eukaryotic B-Family Replicases and Its Implications for Genome Stability	43
The Story of RNA Unfolded: The Molecular Function of DEAD- and DExH-Box ATPases and Their Complex Relationship with Membraneless Organelles	42
Inositol Pyrophosphates as Versatile Metabolic Messengers	40
The Bis(monoacylglycero)-phosphate Hypothesis: From Lysosomal Function to Therapeutic Avenues	40
Encapsulins	40
Lipid Quality Control and Ferroptosis: From Concept to Mechanism	38
Looping the Genome with SMC Complexes	34
Soluble Human Lectins at the Host–Microbe Interface	34
Inhibiting Lipopolysaccharide Biogenesis: The More You Know the Further You Go	33
Rubisco Function, Evolution, and Engineering	32
	31
Sensory TRP Channels in Three Dimensions	27
Structure and Mechanism of the Lipid Flippase MurJ	26
Macrocyclization and Backbone Modification in RiPP Biosynthesis	24
Eukaryotic Microproteins	24
Nonlytic Egress and Transmission in the Virus World	24
MAPK-Activated Protein Kinases: Servant or Partner?	24
Triumphs and Challenges of Natural Product Discovery in the Postgenomic Era	22
Kinetic Proofreading	22
Polyamines in Parkinson's Disease: Balancing Between Neurotoxicity and Neuroprotection	22
Molecular Mechanisms of Transcription-Coupled Repair	21