OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Biochemistry is 23. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
The Role of DEAD-Box ATPases in Gene Expression and the Regulation of RNA–Protein Condensates	369
Emerging Approaches for Studying Lipid Dynamics, Metabolism, and Interactions in Cells	202
Lipid Dynamics at Membrane Contact Sites	174
The Initiation of Eukaryotic DNA Replication	172
Moonlighting Enzymes at the Interface Between Metabolism and Epigenetics	123
The Purinosome: A Case Study for a Mammalian Metabolon	115
The Structural Dynamics of Translation	109
Mitochondrial DNA Release in Innate Immune Signaling	102
DNA Damage and Replication Stress Checkpoints	96
Mechanisms of General Anesthesia	93
The Inseparable Relationship Between Cholesterol and Hedgehog Signaling	88
Signaling from RAS to RAF: The Molecules and Their Mechanisms	86
Emerging Chemical Diversity and Potential Applications of Enzymes in the DMSO Reductase Superfamily	79
High-Resolution Single-Molecule Magnetic Tweezers	77
mRNA Regulation by RNA Modifications	74
Eukaryotic Ribosome Assembly	73
Topoisomerase Regulation of Cancer Gene Expression	71
DNA–Protein Crosslinks and Their Resolution	63
Structural Biochemistry of Muscle Contraction	59
Membrane Protein Complexity Revealed Through Native Mass Spectrometry	57
Essential Biology of Lipid Droplets	57
Validating Small Molecule Chemical Probes for Biological Discovery	56
The Nicotinic Acetylcholine Receptor and Its Pentameric Homologs: Toward an Allosteric Mechanism of Signal Transduction at the Atomic Level	54
	53
Natural and Engineered Guide RNA–Directed Transposition with CRISPR-Associated Tn7-Like Transposons	48

Influence of Nonspecific Interactions on Protein Associations: Implications for Biochemistry In Vivo	47
Lipid Quality Control and Ferroptosis: From Concept to Mechanism	46
Encapsulins	46
The Story of RNA Unfolded: The Molecular Function of DEAD- and DExH-Box ATPases and Their Complex Relationship with Membraneless Organelles	44
Inositol Pyrophosphates as Versatile Metabolic Messengers	43
The Bis(monoacylglycero)-phosphate Hypothesis: From Lysosomal Function to Therapeutic Avenues	43
Ribonucleotide Incorporation by Eukaryotic B-Family Replicases and Its Implications for Genome Stability	43
Soluble Human Lectins at the Host–Microbe Interface	42
Inhibiting Lipopolysaccharide Biogenesis: The More You Know the Further You Go	39
Rubisco Function, Evolution, and Engineering	39
Looping the Genome with SMC Complexes	37
	32
Nonlytic Egress and Transmission in the Virus World	32
Sensory TRP Channels in Three Dimensions	30
Macrocyclization and Backbone Modification in RiPP Biosynthesis	30
Structure and Mechanism of the Lipid Flippase MurJ	29
MAPK-Activated Protein Kinases: Servant or Partner?	28
Eukaryotic Microproteins	25
Triumphs and Challenges of Natural Product Discovery in the Postgenomic Era	25
Polyamines in Parkinson's Disease: Balancing Between Neurotoxicity and Neuroprotection	24
Kinetic Proofreading	24
Biochemistry, Cell Biology, and Pathophysiology of the Innate Immune cGAS–cGAMP–STING Pathway	23
Molecular Mechanisms of Transcription-Coupled Repair	23