OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Biochemistry is 20. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Preparing Better Samples for Cryo–Electron Microscopy: Biochemical Challenges Do Not End with Isolation and Purification	281
Short- and Long-Term Adaptation to Altered Levels of Glucose: Fifty Years of Scientific Adventure	176
From Bioorganic Models to Cells	165
	121
Thiolase: A Versatile Biocatalyst Employing Coenzyme A–Thioester Chemistry for Making and Breaking C–C Bonds	118
Quality Control of Procollagen in Cells	109
Managing the Steady State Chromatin Landscape by Nucleosome Dynamics	98
Glycyl Radical Enzymes and Sulfonate Metabolism in the Microbiome	97
The Role of DEAD-Box ATPases in Gene Expression and the Regulation of RNA–Protein Condensates	93
The Roots of Genetic Coding in Aminoacyl-tRNA Synthetase Duality	92
Molecules from the Microbiome	88
Mechanisms for Regulating and Organizing Receptor Signaling by Endocytosis	86
mRNA Regulation by RNA Modifications	84
A Lipid-Raft Theory of Alzheimer's Disease	83
Biochemistry, Cell Biology, and Pathophysiology of the Innate Immune cGAS–cGAMP–STING Pathway	80
High-Resolution Single-Molecule Magnetic Tweezers	78
Eukaryotic Ribosome Assembly	75
The Proteins of mRNA Modification: Writers, Readers, and Erasers	72
Repair of DNA Breaks by Break-Induced Replication	67
Metalloproteomics for Biomedical Research: Methodology and Applications	65
Understanding the Function of Mammalian Sirtuins and Protein Lysine Acylation	61
	60
It's Better To Be Lucky Than Smart	60
Lipid Dynamics at Membrane Contact Sites	57
Influenza Virus RNA-Dependent RNA Polymerase and the Host Transcriptional Apparatus	55

DNA Fragility and Repair: Some Personal Recollections	55
Structure and Mechanism of the Lipid Flippase MurJ	53
Macrocyclization and Backbone Modification in RiPP Biosynthesis	52
Topoisomerase Regulation of Cancer Gene Expression	49
Emerging Approaches for Studying Lipid Dynamics, Metabolism, and Interactions in Cells	45
3′-End Processing of Eukaryotic mRNA: Machinery, Regulation, and Impact on Gene Expression	44
DNA–Protein Crosslinks and Their Resolution	44
Designing Biological Circuits: Synthetic Biology Within the Operon Model and Beyond	43
Heme Oxygenase–Like Metalloenzymes	43
Tunnels for Protein Export from the Endoplasmic Reticulum	43
The Art and Science of Molecular Docking	42
Translation and mRNA Stability Control	41
Sensory TRP Channels in Three Dimensions	40
Structural Mimicry in Microbial and Antimicrobial Amyloids	40
The Initiation of Eukaryotic DNA Replication	38
MAPK-Activated Protein Kinases: Servant or Partner?	38
Chaperoning SNARE Folding and Assembly	38
ATP-Dependent Steps in Peroxisomal Protein Import	37
A Life of Translocations	34
How Natural Enzymes and Synthetic Ribozymes Generate Methylated Nucleotides in RNA	33
PI(4,5)P₂ Clustering and Its Impact on Biological Functions	32
Molecular Machines that Facilitate Bacterial Outer Membrane Protein Biogenesis	31
The Structural Dynamics of Translation	31
The Long Road to Understanding RNAPII Transcription Initiation and Related Syndromes	31
An Overview of Microcrystal Electron Diffraction (MicroED)	30
Validating Small Molecule Chemical Probes for Biological Discovery	29
Extracellular Vesicles and Cellular Homeostasis	27
Moonlighting Enzymes at the Interface Between Metabolism and Epigenetics	27
Structural Biochemistry of Muscle Contraction	27
The Purinosome: A Case Study for a Mammalian Metabolon	27
Synonymous but Not Silent: The Codon Usage Code for Gene Expression and Protein Folding	25
Exploiting Covalent Chemical Labeling with Self-Labeling Proteins	23
Membrane Protein Complexity Revealed Through Native Mass Spectrometry	21
Structural Mechanisms of Topoisomerase-Targeting Drugs	20
The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators	20