OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Medicine is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Carbon Monoxide Poisoning: From Microbes to Therapeutics	550
Clinical Phenotypes of Cystic Fibrosis Carriers	415
Normal Gut Microbiomes in Diverse Populations: Clinical Implications	273
COVID-19 Vaccines: Adenoviral Vectors	264
Whole Inactivated Virus and Protein-Based COVID-19 Vaccines	203
SARS-CoV-2 Vaccination-Induced Thrombotic Thrombocytopenia: A Rare but Serious Immunologic Complication	160
Clonal Expansion of Stem/Progenitor Cells in Cancer, Fibrotic Diseases, and Atherosclerosis, and CD47 Protection of Pathogenic Cells	149
Gender-Affirming Care of Transgender and Gender-Diverse Youth: Current Concepts	145
Treatments for COVID-19	127
New Biological Therapies for Multiple Myeloma	127
New Therapeutic Approaches to Large-Vessel Vasculitis	123
Muscarinic Acetylcholine Receptor Activators as Transformative Therapeutics for Schizophrenia	121
Care Models for Cancer Survivors	109
Cystic Fibrosis Modulator Therapies	108
Club Cell Secretory Protein in Lung Disease: Emerging Concepts and Potential Therapeutics	98
Multispecific CAR T Cells Deprive Lymphomas of Escape via Antigen Loss	88
Health Effects of Wildfire Smoke Exposure	87
Precision Approaches to Chronic Obstructive Pulmonary Disease Management	85
Xenotransplantation: Promises and Perils	84
Advances in Therapy for Refractory Epilepsy	82
Multi-Cancer Early Detection: The New Frontier in Cancer Early Detection	82
Exercise in Octogenarians: How Much Is Too Little?	81
Spontaneous Coronary Artery Dissection: New Insights into This Not-So-Rare Condition	78
Application and Expectations for Immune Checkpoint Blockade of LAG3 and TIGIT	71
COVID-19 and Kidney Disease	65

MELD 3.0 in Advanced Chronic Liver Disease	65
Clinical Perspectives on IgG4-Related Disease and Its Classification	62
Phage Therapy for Antibiotic-Resistant Bacterial Infections	59
Next-Generation Noninvasive Colorectal Cancer Screening	58
Myocardial Infarction with Nonobstructive Coronary Arteries	54
Sleep Health Disparities	54
Genetics of Dilated Cardiomyopathy	50
The Genetic Basis of Sudden Cardiac Death: From Diagnosis to Emerging Genetic Therapies	47
Kawasaki Disease Vasculitis: From Diagnosis to New Concepts in Pathophysiology and Therapeutic Approaches	47
	46
Update on the Porphyrias	45
RASopathies in Cardiac Disease	45
The Hospitalist Movement 25 Years Later	43
Update in Adult Transgender Medicine	42
SARS-CoV-2 Neutralizing Antibodies for COVID-19 Prevention and Treatment	42
SGLT2 Inhibitors: The Sweet Success for Kidneys	40
Update on Hepatorenal Syndrome: From Pathophysiology to Treatment	39
Optimizing KRAS Therapeutics for Non–Small Cell Lung Cancer	38
Emerging Technologies in Cardiac Pacing	36
Effects on Cancer Prevention from the COVID-19 Pandemic	36
Candida auris: Epidemiology and Antifungal Strategy	35
Approach to Therapy for Chronic Pouchitis	34
COVID-19 and Diabetes	34
Endocrine Disorders and COVID-19	34
Progress in the Management of Pancreatic Neuroendocrine Tumors	33
Chronic Cough Hypersensitivity as a Neuropathic Disorder: Implications for Management and New Treatments	33
A Tale of Two Checkpoints: ATR Inhibition and PD-(L)1 Blockade	30
Advances and Applications of Polygenic Scores for Coronary Artery Disease	30
Glucagon-Like Peptide 1 Receptor Agonists and Cardiovascular Disease	27
Adverse Impact of Cannabis on Human Health	27
A Rational Approach to the Treatment of Acute Pulmonary Embolism	27
Update on HIV Chemoprevention	27
Heart Failure with Preserved Ejection Fraction: Mechanisms and Treatment Strategies	26
Primary Aldosteronism and the Role of Mineralocorticoid Receptor Antagonists for the Heart and Kidneys	25
COVID-19 Thrombotic Complications and Therapeutic Strategies	25
	25
Interventional Pulmonology: Extending the Breadth of Thoracic Care	24
Biological Phenotyping in Sepsis and Acute Respiratory Distress Syndrome	24
Clonal Hematopoiesis and Its Impact on Human Health	24
COVID-19: Inflammatory Profile	23
New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based Therapeutics	23
Wearable Devices: Implications for Precision Medicine and the Future of Health Care	23
What Has the Undiagnosed Diseases Network Taught Us About the Clinical Applications of Genomic Testing?	23
COVID-19 Critical Illness: A Data-Driven Review	22
Medical Therapy Alone, Percutaneous Coronary Intervention, or Coronary Artery Bypass Grafting for Treatment of Coronary Artery Disease	22
Maternal Mortality in the United States: Trends and Opportunities for Prevention	21
Subclinical Atrial Fibrillation: A Silent Threat with Uncertain Implications	21
New Oral Selective Estrogen Receptor Degraders Redefine Management of Estrogen Receptor–Positive Breast Cancer	20
Chronic Neuromuscular Respiratory Failure and Home Assisted Ventilation	20
Cytomegalovirus Therapy: Role of Letermovir in Prophylaxis and Treatment in Transplant Recipients	17

Long-Term Risks of Living Kidney Donation: State of the Evidence and Strategies to Resolve Knowledge Gaps	17
Exome/Genome Sequencing in Undiagnosed Syndromes	14
Fatty Liver Disease: Diagnosis and Stratification	14