Essays in Biochemistry

Article	Citations
CRISPR screening in cancer stem cells	404
Ligands and DNA in the allosteric control of retinoid receptors function	120
Harnessing the yeast Saccharomyces cerevisiae for the production of fungal secondary metabolites	109
Phase separation of the microtubule-associated protein tau	106
3D Bioprinting for fabrication of tissue models of COVID-19 infection	91
How viral proteins bind short linear motifs and intrinsically disordered domains	89
Use of electroconductive biomaterials for engineering tissues by 3D printing and 3D bioprinting	82
Butyrate-producing colonic clostridia: picky glycan utilization specialists	81
CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing	80
Salicylic acid and jasmonic acid crosstalk in plant immunity	68
DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling	63
Plant long non-coding RNAs in the regulation of transcription	59
Comparative genomics in the search for conserved long noncoding RNAs	59
Apoplastic and vascular defences	58
Can changes in 3D genome architecture create new regulatory landscapes that contribute to phenotypic evolution?	57
Mineralocorticoid receptor actions in cardiovascular development and disease	54
The role of methionine synthases in fungal metabolism and virulence	50
Malate dehydrogenase: a story of diverse evolutionary radiation	49
Astrocytes in memory formation and maintenance	49
Perspective on pros and cons of microlearning in health education	46
Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being	43
The cGAS-STING pathway in cancer immunity: dual roles, therapeutic strategies, and clinical challenges	42
Plant peroxisome proteostasis—establishing, renovating, and dismantling the peroxisomal proteome	41
A special issue of Essays in Biochemistry on evolutionary developmental biology	40
Branched-chain amino acid biosynthesis in fungi	39

Mass spectrometric insights into protein aggregation	39
O-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases	39
Hemicellulolytic enzymes in lignocellulose processing	36
Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease	36
Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling	36
SINEUPs: a novel toolbox for RNA therapeutics	35
Functional amyloid in a lipid-like environment: a merry dance of many steps	33
Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness	33
Established tools and emerging trends for the production of recombinant proteins and metabolites in Pichia pastoris	32
Systemic acquired resistance-associated transport and metabolic regulation of salicylic acid and glycerol-3-phosphate	32
Nitrification in acidic and alkaline environments	31
Modulating immune cells within pancreatic ductal adenocarcinoma via nanomedicine	31
Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling	31
Phase separation and other forms of α-Synuclein self-assemblies	30
Lipids and the cancer stemness regulatory system in acute myeloid leukemia	30
The molecular basis of cereal grain proteostasis	29
Insight into the structure and molecular mode of action of plant paired NLR immune receptors	28
RNA-binding protein dysfunction in neurodegeneration	28
The road less travelled? Exploring the nuanced evolutionary consequences of duplicated genes	27
Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning	26
Vesicular dysfunction and pathways to neurodegeneration	26
Strategies for inclusion of growth factors into 3D printed bone grafts	25
Nuclear receptor Nur77: its role in chronic inflammatory diseases	25
Plant proteostasis: a proven and promising target for crop improvement	25
Membrane lipid raft homeostasis is directly linked to neurodegeneration	25
Long non-coding RNAs associated with infection and vaccine-induced immunity	24
Functional annotation of lncRNA in high-throughput screening	24
Estrogen receptors and the aging brain	24
Harnessing neutrophil plasticity for HCC immunotherapy	24
Astrocyte heterogeneity and interactions with local neural circuits	23
Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system?	23
Long non-coding RNAs and splicing	23
Evolution of resistance (R) gene specificity	22
Laser-based bioprinting for multilayer cell patterning in tissue engineering and cancer research	22
Sulfate: a neglected (but potentially highly relevant) anion	22
The non-coding genome in genetic brain disorders: new targets for therapy?	22
Acetylation, ADP-ribosylation and methylation of malate dehydrogenase	22
The new age of the phage	22
Saccharomyces cerevisiae strains used industrially for bioethanol production	21
Evo-devo perspectives on cancer	21
Insights into the regulation of malate dehydrogenase: inhibitors, activators, and allosteric modulation by small molecules	21
Crossroads between copper ions and amyloid formation in Parkinson’s disease	21
Quantification of persulfidation on specific proteins: are we nearly there yet?	20
Mitochondrial Ca2+ handling as a cell signaling hub: lessons from astrocyte function	20
How phosphorylation impacts intrinsically disordered proteins and their function	20
Malate dehydrogenase (MDH) in cancer: a promiscuous enzyme, a redox regulator, and a metabolic co-conspirator	20
WNT signaling and cancer stemness	20
Immunotherapy for hypertensive end-organ damage: a new therapeutic strategy	19
The role of the Mediator complex in fungal pathogenesis and response to antifungal agents	19
Immunologically relevant effects of radiation therapy on the tumor microenvironment	18

3D cell aggregate printing technology and its applications	18
Shaping Hox gene activity to generate morphological diversity across vertebrate phylogeny	18
Emerging strategies in lymph node-targeted nano-delivery systems for tumor immunotherapy	18
Molecular divergence with major morphological consequences: development and evolution of organ size and shape	18
The interplay between lytic polysaccharide monooxygenases and glycoside hydrolases	18
Lactic acid bacteria: little helpers for many human tasks	17
Chemical approaches to the sulfation of small molecules: current progress and future directions	17
Specificity and diversity of Klebsiella pneumoniae phage-encoded capsule depolymerases	17
Molecular plant immunity against biotrophic, hemibiotrophic, and necrotrophic fungi	17
Direct recognition of pathogen effectors by plant NLR immune receptors and downstream signalling	17
Production of proteins and commodity chemicals using engineered Bacillus subtilis platform strain	17
Evolution and functional diversification of yeast sugar transporters	17
Manufacturing of animal products by the assembly of microfabricated tissues	16
Cytosolic sulfotransferases in endocrine disruption	16
Gliotoxin and related metabolites as zinc chelators: implications and exploitation to overcome antimicrobial resistance	16
Astrocytes in the pathophysiology of neuroinfection	16
Targeted proteolytic products of τ and α-synuclein in neurodegeneration	16
Mass spectrometry of intact membrane proteins: shifting towards a more native-like context	16
Indirect recognition of pathogen effectors by NLRs	16
A proteostasis network safeguards the chloroplast proteome	16
Cryo-EM structures of τ filaments from human brain	15
Seeing the complete picture: proteins in top-down mass spectrometry	15
Cross-talk between energy and redox metabolism in astrocyte-neuron functional cooperation	15
Is the TCA cycle malate dehydrogenase-citrate synthase metabolon an illusion?	14
Gut bacterial alginate degrading enzymes	14
3D bioprinted and integrated platforms for cardiac tissue modeling and drug testing	14
Mechanisms of resistance to tyrosine kinase inhibitors in liver cancer stem cells and potential therapeutic approaches	14
Kinetic modelling of glycolytic oscillations	14
Unconventional R proteins in the botanical tribe Triticeae	14
Perspectives for the application of Ustilaginaceae as biotech cell factories	14
What’s new in protein kinase/phosphatase signalling in the control of plant immunity?	14
Understanding SUMO-mediated adaptive responses in plants to improve crop productivity	14
The evolutionary acquisition and mode of functions of promoter-associated non-coding RNAs (pancRNAs) for mammalian development	13
So you want to express your protein in Escherichia coli?	13
Targeting protein kinases in cancer stem cells	13
NUAK: never underestimate a kinase	13
Correction: Uncovering protein structure	13
Effect of multimodularity and spatial organization of glycoside hydrolases on catalysis	12
Surface-sampling mass spectrometry to study proteins and protein complexes	12
AMPK and O-GlcNAcylation: interplay in cardiac pathologies and heart failure	12
Phage-specific antibodies: are they a hurdle for the success of phage therapy?	12
Activation and turnover of the plant immune signaling kinase BIK1: a fine balance	12
Non-coding RNA in cancer	12
The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer	12
Developments in rapid hydrogen–deuterium exchange methods	12
Diverse mycotoxin threats to safe food and feed cereals	12
Physiology of malate dehydrogenase and how dysregulation leads to disease	12
Tau aggregation and its relation to selected forms of neuronal cell death	11
Ubiquitin ligases at the nexus of plant responses to biotic and abiotic stresses	11
Different states and the associated fates of biomolecular condensates	11
Engagement with video content in the blended classroom	11
Modelling the evolution of novelty: a review	11
Case Study: CRISPR 101 – a novel online learning course harnessing innovative ways to teach a complex biomolecular technology	11
Lytic polysaccharide monooxygenases: enzymes for controlled and site-specific Fenton-like chemistry	11
Colon cancer checks in when bile acids check out: the bile acid–nuclear receptor axis in colon cancer	11
Oxysterol sulfates in fluids, cells and tissues: how much do we know about their clinical significance, biological relevance and biophysical implications?	11
Saccharomyces cerevisiae as a tool for deciphering Hsp90 molecular chaperone function	11
Microbial cell factories for the production of polyhydroxyalkanoates	11
Microbial cell factories: a biotechnology journey across species	10
Structure and function of microbial α-l-fucosidases: a mini review	10
Unravelling 3D growth in the moss Physcomitrium patens	10
Volatile uptake, transport, perception, and signaling shape a plant’s nose	10
Sulfation pathways in times of change	10
Computational methods for processing and interpreting mass spectrometry-based metabolomics	10
Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses	10
A comparative guide to expression systems for phage lysin production	10
Handheld bioprinting strategies for in situ wound dressing	10
Roles of steroid receptors in the lung and COVID-19	10
Translational research priorities for bacteriophage therapeutics	10
The impact of assessment and feedback practice on the student learning experiences in higher education	10
Mucin utilization by gut microbiota: recent advances on characterization of key enzymes	10
Immune-regulating extracellular vesicles: a new frontier in autoimmune disease therapy	9
Does AMPK bind glycogen in skeletal muscle or is the relationship correlative?	9
Astrocytes as metabolic suppliers to support neuronal activity and brain functions	9
Evolution of SLiM-mediated hijack functions in intrinsically disordered viral proteins	9
Nanomaterials for bioprinting: functionalization of tissue-specific bioinks	9
Progesterone receptors in normal breast development and breast cancer	9
Catalytic mechanism and kinetics of malate dehydrogenase	9
Towards robust Pseudomonas cell factories to harbour novel biosynthetic pathways	8
Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X7R	8

Mechanisms of bioleaching: iron and sulfur oxidation by acidophilic microorganisms	8
Cross-linking mass spectrometry for mapping protein complex topologies in situ	8
PINK1 signalling in neurodegenerative disease	8
Uptake of formative feedback: perspective from a transnational education cohort	8
Mannuronate C-5 epimerases and their use in alginate modification	8
Interplay between phytohormone signalling pathways in plant defence – other than salicylic acid and jasmonic acid	8
HECT ubiquitin ligases as accessory proteins of the plant proteasome	8
Inflammasome activation in neurodegenerative diseases	8
Ubiquitination of the ubiquitin-binding machinery: how early ESCRT components are controlled	8
New molecules in plant defence against pathogens	8
Rab GTPases in Parkinson's disease: a primer	8