Essays in Biochemistry

Article	Citations
CRISPR screening in cancer stem cells	447
Ligands and DNA in the allosteric control of retinoid receptors function	126
Phase separation of the microtubule-associated protein tau	120
Butyrate-producing colonic clostridia: picky glycan utilization specialists	117
How viral proteins bind short linear motifs and intrinsically disordered domains	98
Use of electroconductive biomaterials for engineering tissues by 3D printing and 3D bioprinting	91
CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing	90
3D Bioprinting for fabrication of tissue models of COVID-19 infection	85
Salicylic acid and jasmonic acid crosstalk in plant immunity	72
Plant long non-coding RNAs in the regulation of transcription	65
Malate dehydrogenase: a story of diverse evolutionary radiation	57
Perspective on pros and cons of microlearning in health education	52
Mineralocorticoid receptor actions in cardiovascular development and disease	51
The role of methionine synthases in fungal metabolism and virulence	49
Astrocytes in memory formation and maintenance	47
Comparative genomics in the search for conserved long noncoding RNAs	44
DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling	43
Can changes in 3D genome architecture create new regulatory landscapes that contribute to phenotypic evolution?	43
Apoplastic and vascular defences	42
A special issue of Essays in Biochemistry on evolutionary developmental biology	40
Branched-chain amino acid biosynthesis in fungi	40
Mass spectrometric insights into protein aggregation	40
O-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases	37
The cGAS-STING pathway in cancer immunity: dual roles, therapeutic strategies, and clinical challenges	36
Plant peroxisome proteostasis—establishing, renovating, and dismantling the peroxisomal proteome	36

Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease	36
SINEUPs: a novel toolbox for RNA therapeutics	34
Systemic acquired resistance-associated transport and metabolic regulation of salicylic acid and glycerol-3-phosphate	33
Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling	32
Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness	32
Nitrification in acidic and alkaline environments	32
Functional amyloid in a lipid-like environment: a merry dance of many steps	32
Modulating immune cells within pancreatic ductal adenocarcinoma via nanomedicine	30
Hemicellulolytic enzymes in lignocellulose processing	29
Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling	29
Lipids and the cancer stemness regulatory system in acute myeloid leukemia	28
RNA-binding protein dysfunction in neurodegeneration	28
Insight into the structure and molecular mode of action of plant paired NLR immune receptors	28
Phase separation and other forms of α-Synuclein self-assemblies	28
Vesicular dysfunction and pathways to neurodegeneration	27
The molecular basis of cereal grain proteostasis	27
Membrane lipid raft homeostasis is directly linked to neurodegeneration	25
Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning	25
Plant proteostasis: a proven and promising target for crop improvement	25
The road less travelled? Exploring the nuanced evolutionary consequences of duplicated genes	25
Strategies for inclusion of growth factors into 3D printed bone grafts	25
Nuclear receptor Nur77: its role in chronic inflammatory diseases	24
Estrogen receptors and the aging brain	24
Oxidative stress – Alzheimer’s disease – DNA methylation: the role of arsenic	22
Laser-based bioprinting for multilayer cell patterning in tissue engineering and cancer research	22
Evolution of resistance (R) gene specificity	22
Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system?	22
Long non-coding RNAs associated with infection and vaccine-induced immunity	22
Functional annotation of lncRNA in high-throughput screening	21
Harnessing neutrophil plasticity for HCC immunotherapy	21
Astrocyte heterogeneity and interactions with local neural circuits	21
Long non-coding RNAs and splicing	21
Sulfate: a neglected (but potentially highly relevant) anion	21
Evo-devo perspectives on cancer	20
The non-coding genome in genetic brain disorders: new targets for therapy?	20
The new age of the phage	19
Acetylation, ADP-ribosylation and methylation of malate dehydrogenase	19
Crossroads between copper ions and amyloid formation in Parkinson’s disease	19
How phosphorylation impacts intrinsically disordered proteins and their function	18
Insights into the regulation of malate dehydrogenase: inhibitors, activators, and allosteric modulation by small molecules	18
The role of the Mediator complex in fungal pathogenesis and response to antifungal agents	18
WNT signaling and cancer stemness	18
Malate dehydrogenase (MDH) in cancer: a promiscuous enzyme, a redox regulator, and a metabolic co-conspirator	18
Quantification of persulfidation on specific proteins: are we nearly there yet?	18
Mitochondrial Ca2+ handling as a cell signaling hub: lessons from astrocyte function	18
Shaping Hox gene activity to generate morphological diversity across vertebrate phylogeny	17
Specificity and diversity of Klebsiella pneumoniae phage-encoded capsule depolymerases	17
Immunotherapy for hypertensive end-organ damage: a new therapeutic strategy	17
3D cell aggregate printing technology and its applications	17
The interplay between lytic polysaccharide monooxygenases and glycoside hydrolases	17

Immunologically relevant effects of radiation therapy on the tumor microenvironment	17
Molecular divergence with major morphological consequences: development and evolution of organ size and shape	17
Direct recognition of pathogen effectors by plant NLR immune receptors and downstream signalling	17
Targeted proteolytic products of τ and α-synuclein in neurodegeneration	16
Emerging strategies in lymph node-targeted nano-delivery systems for tumor immunotherapy	16
Cytosolic sulfotransferases in endocrine disruption	16
Chemical approaches to the sulfation of small molecules: current progress and future directions	16
Evolution and functional diversification of yeast sugar transporters	16
Gliotoxin and related metabolites as zinc chelators: implications and exploitation to overcome antimicrobial resistance	16
Molecular plant immunity against biotrophic, hemibiotrophic, and necrotrophic fungi	16
Mass spectrometry of intact membrane proteins: shifting towards a more native-like context	15
Manufacturing of animal products by the assembly of microfabricated tissues	15
Astrocytes in the pathophysiology of neuroinfection	15
Cross-talk between energy and redox metabolism in astrocyte-neuron functional cooperation	15
Seeing the complete picture: proteins in top-down mass spectrometry	15
Indirect recognition of pathogen effectors by NLRs	15
A proteostasis network safeguards the chloroplast proteome	15
Unconventional R proteins in the botanical tribe Triticeae	15
Cryo-EM structures of τ filaments from human brain	14
Understanding SUMO-mediated adaptive responses in plants to improve crop productivity	14
3D bioprinted and integrated platforms for cardiac tissue modeling and drug testing	14
Mechanisms of resistance to tyrosine kinase inhibitors in liver cancer stem cells and potential therapeutic approaches	14
Targeting protein kinases in cancer stem cells	14
Is the TCA cycle malate dehydrogenase-citrate synthase metabolon an illusion?	14
Kinetic modelling of glycolytic oscillations	14
The evolutionary acquisition and mode of functions of promoter-associated non-coding RNAs (pancRNAs) for mammalian development	14
Gut bacterial alginate degrading enzymes	14
What’s new in protein kinase/phosphatase signalling in the control of plant immunity?	14
Effect of multimodularity and spatial organization of glycoside hydrolases on catalysis	13
Diverse mycotoxin threats to safe food and feed cereals	13
Activation and turnover of the plant immune signaling kinase BIK1: a fine balance	13
Phage-specific antibodies: are they a hurdle for the success of phage therapy?	13
NUAK: never underestimate a kinase	13
Developments in rapid hydrogen–deuterium exchange methods	13
Non-coding RNA in cancer	13
Surface-sampling mass spectrometry to study proteins and protein complexes	12
AMPK and O-GlcNAcylation: interplay in cardiac pathologies and heart failure	12
The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer	11
Case Study: CRISPR 101 – a novel online learning course harnessing innovative ways to teach a complex biomolecular technology	11
Oxysterol sulfates in fluids, cells and tissues: how much do we know about their clinical significance, biological relevance and biophysical implications?	11
Engagement with video content in the blended classroom	11
Lytic polysaccharide monooxygenases: enzymes for controlled and site-specific Fenton-like chemistry	11
Ubiquitin ligases at the nexus of plant responses to biotic and abiotic stresses	11
Saccharomyces cerevisiae as a tool for deciphering Hsp90 molecular chaperone function	11
Different states and the associated fates of biomolecular condensates	11
Structure and function of microbial α-l-fucosidases: a mini review	11
Computational methods for processing and interpreting mass spectrometry-based metabolomics	11
Modelling the evolution of novelty: a review	11
Physiology of malate dehydrogenase and how dysregulation leads to disease	11
Tau aggregation and its relation to selected forms of neuronal cell death	11
Colon cancer checks in when bile acids check out: the bile acid–nuclear receptor axis in colon cancer	11
Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses	11
Progesterone receptors in normal breast development and breast cancer	10
Translational research priorities for bacteriophage therapeutics	10
Nanomaterials for bioprinting: functionalization of tissue-specific bioinks	10
Handheld bioprinting strategies for in situ wound dressing	10
Roles of steroid receptors in the lung and COVID-19	10
A comparative guide to expression systems for phage lysin production	10
Volatile uptake, transport, perception, and signaling shape a plant’s nose	10
Unravelling 3D growth in the moss Physcomitrium patens	10
Sulfation pathways in times of change	10
The impact of assessment and feedback practice on the student learning experiences in higher education	9
Does AMPK bind glycogen in skeletal muscle or is the relationship correlative?	9
Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X7R	9
Ubiquitination of the ubiquitin-binding machinery: how early ESCRT components are controlled	9
Immune-regulating extracellular vesicles: a new frontier in autoimmune disease therapy	9
Evolution of SLiM-mediated hijack functions in intrinsically disordered viral proteins	9
Mechanisms of bioleaching: iron and sulfur oxidation by acidophilic microorganisms	9
Mucin utilization by gut microbiota: recent advances on characterization of key enzymes	9
Astrocytes as metabolic suppliers to support neuronal activity and brain functions	9
Catalytic mechanism and kinetics of malate dehydrogenase	9
Mannuronate C-5 epimerases and their use in alginate modification	8
Cross-linking mass spectrometry for mapping protein complex topologies in situ	8
Understanding and computational design of genetic circuits of metabolic networks	8
Introduction to bioprinting of in vitro cancer models	8
HECT ubiquitin ligases as accessory proteins of the plant proteasome	8
PINK1 signalling in neurodegenerative disease	8
Inflammasome activation in neurodegenerative diseases	8
Steroid sulfatase and sulfotransferases in the estrogen and androgen action of gynecological cancers: current status and perspectives	8
Uptake of formative feedback: perspective from a transnational education cohort	8

Rab GTPases in Parkinson's disease: a primer	8
New molecules in plant defence against pathogens	8
Interplay between phytohormone signalling pathways in plant defence – other than salicylic acid and jasmonic acid	8
A special issue of Essays in Biochemistry on current educational developments in molecular bioscience	8
Carbohydrate esterases involved in deacetylation of food components by the human gut microbiota	8