OOIR: Observatory of International Research

Papers

(The TQCC of Essays in Biochemistry is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
CRISPR screening in cancer stem cells	404
Ligands and DNA in the allosteric control of retinoid receptors function	120
Harnessing the yeast Saccharomyces cerevisiae for the production of fungal secondary metabolites	109
Phase separation of the microtubule-associated protein tau	106
3D Bioprinting for fabrication of tissue models of COVID-19 infection	91
How viral proteins bind short linear motifs and intrinsically disordered domains	89
Use of electroconductive biomaterials for engineering tissues by 3D printing and 3D bioprinting	82
Butyrate-producing colonic clostridia: picky glycan utilization specialists	81
CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing	80
Salicylic acid and jasmonic acid crosstalk in plant immunity	68
DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS–STING signalling	63
Plant long non-coding RNAs in the regulation of transcription	59
Comparative genomics in the search for conserved long noncoding RNAs	59
Apoplastic and vascular defences	58
Can changes in 3D genome architecture create new regulatory landscapes that contribute to phenotypic evolution?	57
Mineralocorticoid receptor actions in cardiovascular development and disease	54
The role of methionine synthases in fungal metabolism and virulence	50
Malate dehydrogenase: a story of diverse evolutionary radiation	49
Astrocytes in memory formation and maintenance	49
Perspective on pros and cons of microlearning in health education	46
Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being	43
The cGAS-STING pathway in cancer immunity: dual roles, therapeutic strategies, and clinical challenges	42
Plant peroxisome proteostasis—establishing, renovating, and dismantling the peroxisomal proteome	41
A special issue of Essays in Biochemistry on evolutionary developmental biology	40
Branched-chain amino acid biosynthesis in fungi	39

Mass spectrometric insights into protein aggregation	39
O-Mucin-degrading carbohydrate-active enzymes and their possible implication in inflammatory bowel diseases	39
Hemicellulolytic enzymes in lignocellulose processing	36
Shapeshifting proteins: the role of structural disorder and conformational plasticity in physiology and disease	36
Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling	36
SINEUPs: a novel toolbox for RNA therapeutics	35
Functional amyloid in a lipid-like environment: a merry dance of many steps	33
Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness	33
Established tools and emerging trends for the production of recombinant proteins and metabolites in Pichia pastoris	32
Systemic acquired resistance-associated transport and metabolic regulation of salicylic acid and glycerol-3-phosphate	32
Nitrification in acidic and alkaline environments	31
Modulating immune cells within pancreatic ductal adenocarcinoma via nanomedicine	31
Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling	31
Lipids and the cancer stemness regulatory system in acute myeloid leukemia	30
Phase separation and other forms of α-Synuclein self-assemblies	30
The molecular basis of cereal grain proteostasis	29
RNA-binding protein dysfunction in neurodegeneration	28
Insight into the structure and molecular mode of action of plant paired NLR immune receptors	28
The road less travelled? Exploring the nuanced evolutionary consequences of duplicated genes	27
Vesicular dysfunction and pathways to neurodegeneration	26
Long non-coding RNA and ribosomal protein genes in a yeast ageing model: an investigation for undergraduate research-based learning	26
Nuclear receptor Nur77: its role in chronic inflammatory diseases	25
Plant proteostasis: a proven and promising target for crop improvement	25
Membrane lipid raft homeostasis is directly linked to neurodegeneration	25
Strategies for inclusion of growth factors into 3D printed bone grafts	25
Functional annotation of lncRNA in high-throughput screening	24
Estrogen receptors and the aging brain	24
Harnessing neutrophil plasticity for HCC immunotherapy	24
Long non-coding RNAs associated with infection and vaccine-induced immunity	24
Astroglial CB1 receptors, energy metabolism, and gliotransmission: an integrated signaling system?	23
Long non-coding RNAs and splicing	23
Astrocyte heterogeneity and interactions with local neural circuits	23
Evolution of resistance (R) gene specificity	22
Laser-based bioprinting for multilayer cell patterning in tissue engineering and cancer research	22
Sulfate: a neglected (but potentially highly relevant) anion	22
The non-coding genome in genetic brain disorders: new targets for therapy?	22
Acetylation, ADP-ribosylation and methylation of malate dehydrogenase	22
The new age of the phage	22
Saccharomyces cerevisiae strains used industrially for bioethanol production	21
Evo-devo perspectives on cancer	21
Insights into the regulation of malate dehydrogenase: inhibitors, activators, and allosteric modulation by small molecules	21
Crossroads between copper ions and amyloid formation in Parkinson’s disease	21
Mitochondrial Ca2+ handling as a cell signaling hub: lessons from astrocyte function	20
How phosphorylation impacts intrinsically disordered proteins and their function	20
Malate dehydrogenase (MDH) in cancer: a promiscuous enzyme, a redox regulator, and a metabolic co-conspirator	20
WNT signaling and cancer stemness	20
Quantification of persulfidation on specific proteins: are we nearly there yet?	20
Immunotherapy for hypertensive end-organ damage: a new therapeutic strategy	19
The role of the Mediator complex in fungal pathogenesis and response to antifungal agents	19
Shaping Hox gene activity to generate morphological diversity across vertebrate phylogeny	18

Emerging strategies in lymph node-targeted nano-delivery systems for tumor immunotherapy	18
Molecular divergence with major morphological consequences: development and evolution of organ size and shape	18
The interplay between lytic polysaccharide monooxygenases and glycoside hydrolases	18
Immunologically relevant effects of radiation therapy on the tumor microenvironment	18
3D cell aggregate printing technology and its applications	18