OOIR: Observatory of International Research

Papers

(The TQCC of Memorias do Instituto Oswaldo Cruz is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Antileishmanial metallodrugs and the elucidation of new drug targets linked to post-translational modifications machinery: pitfalls and progress	55
Sublingual microcirculatory alterations in Chagas disease: an observational study in an endemic rural population	37
Insecticide resistance levels and associated mechanisms in three Aedes aegypti populations from Venezuela	32
First concrete documentation for presence of Aedes (Stegomyia) albopictus in Bolivia: dispelling previous anecdotes	30
PPE59 antibodies in tuberculous patients and potential use for diagnosis when assayed with other rapid biomarkers	29
Impact of dengue virus infection on the cytoadherence of Plasmodium vivax-infected erythrocytes	22
Genome characterisation of the first isolate of human enterovirus c99 from an acute flaccid paralysis case in Brazil	22
A multicentre comparative study of serological methods for diagnosing Chagas disease in Brazil	17
Genomic surveillance: a potential shortcut for effective Chagas disease management	17
Pharmacokinetics of two pharmaceutical presentations of benznidazole in adult Trypanosoma cruzi infected population	16
Memórias do Instituto Oswaldo Cruz celebrates 115 years of scientific publishing: what it needs to keep moving on…	16
Revisiting Chagas' disease diagnostic strategies in light of different scenarios of Trypanosoma cruzi infection	16
Antileishmanial metallodrugs and the elucidation of new drug targets linked to post-translational modifications machinery: pitfalls and progress	16
How people affected by Chagas disease have struggled with their negligence: history, associative movement and World Chagas Disease Day	15
Why do we still have not a vaccine against Chagas disease?	15
Improving in vitro screening compounds anti-Trypanosoma cruzi by GFP-expressing parasites	12
Plants of the family Lamiaceae as a source of therapeutic agents against Acanthamoeba infections	12
Challenges in developing new tuberculosis vaccines	11
Characterisation of Neisseria meningitidis cc11/ET-15 variant by whole genome sequencing	11
Intravenous whole blood transfusion results in faster recovery of vascular integrity and increased survival in experimental cerebral malaria	10
Trypanosoma cruzi and Chagas disease: diversity, progress and challenges	10
Transforming growth factor-ß as a therapeutic target for the cardiac damage of Chagas disease	10
Surveillance of land molluscs infected by Angiostrongylus cantonensis (Nematoda) reveals risk areas for zoonotic eosinophilic meningitis in the State of Rio de Janeiro, Brazil	9
In vitro activity of Schinus terebinthifolius extract and fractions against Sporothrix brasiliensis	9
The multidimensional comprehension of Chagas disease. Contributions, approaches, challenges and opportunities from and beyond the Information, Education and Communication field	9

Significance of a neglected tropical disease: lessons from a paradigmatic case of ‘success in translation’	8
Cross-sectional entomological monitoring combined with professional qualifications in transition areas for yellow fever and autochthonous malaria in the Atlantic Forest in Rio de Janeiro, Brazil	8
Heterochromatin protein 1 (HP1) of Schistosoma mansoni: non-canonical chromatin landscape and oviposition effects	8
Perillyl alcohol modulates activation, permeability and integrity of human brain endothelial cells induced by Plasmodium falciparum	7
Iron and vitamin D intake on a diet are able to modify the in vitro immune response to Mycobacterium leprae	7
A review of serological tests available in Brazil for intestinal schistosomiasis diagnosis	7
Antioxidant defence system as a rational target for Chagas disease and Leishmaniasis chemotherapy	7
Polyunsaturated fatty acids alter the formation of lipid droplets and eicosanoid production in Leishmania promastigotes	7
Diphtheria antitoxin treatment: from pioneer to neglected	6
Leishmania (Leishmania) infantum DNA detection in Nyssomyia neivai in Vale do Ribeira, Paraná, Brazil	6
Host cholesterol influences the activity of sterol biosynthesis inhibitors in Leishmania amazonensis	6
Evaluation of the influence of genetic variants in Cereblon gene on the response to the treatment of erythema nodosum leprosum with thalidomide	6
Congenital Zika virus infection in laboratory animals: a comparative review highlights translational studies on the maternal-foetal interface	6
Chagas disease in the context of the 2030 agenda: global warming and vectors	6
First report of Leishmania RNA virus 1 in Leishmania (Viannia) braziliensis clinical isolates from Rio de Janeiro State - Brazil	6
125 years of the plague in Brazil: lessons learnt, historical insights and contemporary challenges	6
Natural compounds based chemotherapeutic against Chagas disease and leishmaniasis: mitochondrion as a strategic target	6
Heavy metal resistance in the Yanomami and Tunapuco microbiome	6
Concomitant occurrence of chronic Schistosoma mansoni infection and chronic colitis restore immune imbalance and dysbiosis leading to protection against intestinal colitis and schistosome egg-induced	5
Peeking into the mysterious world of Trypanosoma cruzi and Chagas disease	5
Unique synapomorphies and high diversity in South American Raji-related Epstein-Barr virus genomes	5
Translational research in Chagas disease: perspectives in nutritional therapy emerging from selenium supplementation studies as a complementary treatment	5
Binding of the extracellular matrix laminin-1 to Clostridioides difficile strains	5
Reflections on Chagas disease in the Amazon	4
Chikungunya virus infection in the southernmost state of Brazil was characterised by self-limited transmission (2017-2019) and a larger 2021 outbreak	4
Exploring BCG to deliver avidin fusion antigens from Schistosoma mansoni	4
Challenges and perspectives in research and teaching of host pathogen interaction topics: new post-pandemic times to Brazil and other South American countries	4
Pathophysiology and new targets for therapeutic options in Chagas heart disease	4
Increased angiogenesis parallels cardiac tissue remodelling in experimental acute Trypanosoma cruzi infection	4
Investigating the distribution of a rare Colombo-Venezuelan kissing bug, Rhodnius neivai, Lent, 1953, using geographical information system-based analyses	4
New possibilities for chromoblastomycosis and phaeohyphomycosis treatment: identification of two compounds from the MMV Pathogen Box® that present synergism with itraconazole	4
The risk of vector transmission of Trypanosoma cruzi remains high in the State of Paraná	4
Aedes aegypti reproductive aspects: constant light significantly affects the embryonic development	4
Clinical and epidemiological aspects of Delta and Gamma SARS-CoV-2 variant of concern from the western Brazilian Amazon	3
A newly bat-borne hantavirus detected in Seba’s short-tailed bats (Carollia perspicillata) in the Brazilian Atlantic Rainforest	3
The translational challenge in Chagas disease drug development	3
Long COVID-19 syndrome associated with Omicron XBB.1.5 infection: a case report	3
Microbiome and virome on indoor surfaces of an Antarctic research ship	3
Different profiles of chemokines, cytokines and cell growth factors in plasma samples from patients with leprosy, leprosy reactions and households contacts	3
COVID-19 outbreaks among crew members in non-cruise vessels anchoring in Salvador, Brazil, 2021	3
Chagas disease treatment: a 120-year-old challenge to public health	3
Critical analysis of Chagas disease treatment in different countries	3
Cerebrospinal fluid: a target of some fungi and an overview	3
Waiting for a success story in prevention, control and treatment of Chagas disease in non-endemic countries	3
Population size regulation is density-dependent in Rhodnius prolixus (Hemiptera: Reduviidae) through an irritability mechanism	3
Accuracy of rapid point-of-care serological tests for leprosy diagnosis: a systematic review and meta-analysis	3