OOIR: Observatory of International Research

Papers

(The TQCC of Progress in Biophysics & Molecular Biology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Ferroptosis as an emerging target in inflammatory diseases	113
Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies	67
In-silico human electro-mechanical ventricular modelling and simulation for drug-induced pro-arrhythmia and inotropic risk assessment	53
Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease	44
Multimodal on-axis platform for all-optical electrophysiology with near-infrared probes in human stem-cell-derived cardiomyocytes	40
Cytochrome bd in Mycobacterium tuberculosis: A respiratory chain protein involved in the defense against antibacterials	38
Bioelectrical approaches to cancer as a problem of the scaling of the cellular self	38
Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors	38
ROS-induced cell cycle arrest as a mechanism of resistance in polyaneuploid cancer cells (PACCs)	37
Compressed sensing in fluorescence microscopy	33
Human coronavirus spike protein-host receptor recognition	32
Removing striping artifacts in light-sheet fluorescence microscopy: a review	31
Localized reconstruction in Scipion expedites the analysis of symmetry mismatches in cryo-EM data	30
Towards high-throughput in situ structural biology using electron cryotomography	29
Forecasting the timeframe of 2019-nCoV and human cells interaction with reverse engineering	29
Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation	29
Targeting the cytochrome oxidases for drug development in mycobacteria	29
A free energy principle for generic quantum systems	28
Intrinsic disorder in proteins: Relevance to protein assemblies, drug design and host-pathogen interactions	28
Beyond the modern synthesis: A framework for a more inclusive biological synthesis	27
Mesoscale microscopy and image analysis tools for understanding the brain	27
The multiple biological roles of the cholinesterases	27
Ih from synapses to networks: HCN channel functions and modulation in neurons	26
Mechanosensitive TREK-1 two-pore-domain potassium (K2P) channels in the cardiovascular system	26
Curcumin and cancer; are long non-coding RNAs missing link?	25

Three-dimensional encapsulation of adult mouse cardiomyocytes in hydrogels with tunable stiffness	25
Unique structural and mechanistic properties of mycobacterial F-ATP synthases: Implications for drug design	23
The murburn precepts for aerobic respiration and redox homeostasis	23
Two-phased evolution: Genome chaos-mediated information creation and maintenance	23
A specific role of magnetic isotopes in biological and ecological systems. Physics and biophysics beyond	23
Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents	23
What prevents mainstream evolutionists teaching the whole truth about how genomes evolve?	21
Cardiac pacing using transmural multi-LED probes in channelrhodopsin-expressing mouse hearts	21
An overview of the vaccine platforms to combat COVID-19 with a focus on the subunit vaccines	20
The role of stochasticity in biological communication processes	20
Computational models of cardiac hypertrophy	19
The resolution revolution in X-ray diffraction, Cryo-EM and other Technologies	19
Towards a clearer view of sympathetic innervation of cardiac and skeletal muscles	19
Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response	18
Cellular senomic measurements in Cognition-Based Evolution	18
Living systems approached from physical principles	18
The gene: An appraisal	17
A systematic review on machine learning and deep learning techniques in cancer survival prediction	17
Quantum information theoretic approach to the mind–brain problem	17
Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease	17
Beyond pacemaking: HCN channels in sinoatrial node function	17
Transfer RNA: The molecular demiurge in the origin of biological systems	17
Fanconi anemia-independent DNA inter-strand crosslink repair in eukaryotes	16
Treasuring the computational approach in medicinal plant research	16
Biophysical analysis of an HCN1 epilepsy variant suggests a critical role for S5 helix Met-305 in voltage sensor to pore domain coupling	16
Non-canonical roles of connexins	15
In vitro cell stretching technology (IsoStretcher) as an approach to unravel Piezo1-mediated cardiac mechanotransduction	15
New role of TRPM4 channel in the cardiac excitation-contraction coupling in response to physiological and pathological hypertrophy in mouse	15
Introduction: Novel insights into TB research and drug discovery	14
Mathematical modelling of the mechano-electric coupling in the human cardiomyocyte electrically connected with fibroblasts	14
Cellular Darwinism: Regulatory networks, stochasticity, and selection in cancer development	14
DNA replication stress and emerging prospects for PARG inhibitors in ovarian cancer therapy	14
Unique structural features of the Mycobacterium ribosome	14
Roles of ATM and ATR in DNA double strand breaks and replication stress	14
Recent progress in optical voltage-sensor technology and applications to cardiac research: from single cells to whole hearts	14
Tools for visualizing and analyzing Fourier space sampling in Cryo-EM	14
Targeted protein degradation in antibacterial drug discovery?	14
Different methods, techniques and their limitations in protein structure prediction: A review	13
Biophysical mechanisms underlying the effects of static magnetic fields on biological systems	13
Inosine and its methyl derivatives: Occurrence, biogenesis, and function in RNA	13
Xanthohumol: An underestimated, while potent and promising chemotherapeutic agent in cancer treatment	13
Advances in the understanding of protein misfolding and aggregation through molecular dynamics simulation	13
Life is a mobius strip	13
Ca2+ currents in cardiomyocytes: How to improve interpretation of patch clamp data?	13
Reverting to single-cell biology: The predictions of the atavism theory of cancer	13
T cell receptors, mechanosensors, catch bonds and immunotherapy	13
The funny current: Even funnier than 40 years ago. Uncanonical expression and roles of HCN/f channels all over the body	13
The living state: How cellular excitability is controlled by the thermodynamic state of the membrane	13
State-dependent sequential allostery exhibited by chaperonin TRiC/CCT revealed by network analysis of Cryo-EM maps	12
An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation	12

What can evolutionary biology learn from cancer biology?	12
The role of mechanosensitive Piezo1 channel in diseases	12
Action potential alterations induced by single F11 neuronal cell loading	12
The HCN channel as a pharmacological target: Why, where, and how to block it	12
The ATPases of the mycobacterial type VII secretion system: Structural and mechanistic insights into secretion	11
Computational techniques for the automated detection of mycobacterium tuberculosis from digitized sputum smear microscopic images: A systematic review	11
No light without the dark: Perspectives and hindrances for translation of cardiac optogenetics	11
Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM	11
Editorial: Charles Darwin, Jean-Baptiste Lamarck, and 21st century arguments on the fundamentals of biology	11
Further insights into the molecular complexity of the human sinus node – The role of ‘novel’ transcription factors and microRNAs	11
The biological effects of radiation-induced liver damage and its natural protective medicine	11
Structural interpretation of cryo-EM image reconstructions	11
The important consequences of the reversible heat production in nerves and the adiabaticity of the action potential	11
HCN4 current during human sinoatrial node-like action potentials	11
Biology transcends the limits of computation	11
The thermodynamic soliton theory of the nervous impulse and possible medical implications	10
High resolution single particle Cryo-EM refinement using JSPR	10
Efficient metadata mining of web-accessible neural morphologies	10
From leaves to roots: Biophysical models of transport of substances in plants	10
Exosomes in bone remodeling and breast cancer bone metastasis	10
DNA glycosylase NEIL2 functions in multiple cellular processes	10
Re-visiting the Frank-Starling nexus	10
The somatic molecular evolution of cancer: Mutation, selection, and epistasis	10
Do the functional properties of HCN1 mutants correlate with the clinical features in epileptic patients?	10
Do plants pay attention? A possible phenomenological-empirical approach	10
Autonomic modulation of sinoatrial node: Role of pacemaker current and calcium sensitive adenylyl cyclase isoforms	10
Clustering polymorphs of tau and IAPP fibrils with the CHEP algorithm	10
Optical clearing in cardiac imaging: A comparative study	10
The role of viscoelasticity in long time cell rearrangement	10