Kidney International

Article	Citations
In This Issue	2344
Table of Contents	850
Subscription Information	452
Taking the A(llorecognition) train: connecting passenger T cells to DSA	278
in this issue	261
Thirsty encounters of the third kind	239
Misuse of the Cox proportional hazards model and alternative approaches in kidney outcome research	223
Identification of the gut microbial enzyme turning the urine yellow	216
A pig kidney supporting human physiology	201
Gene editing: a near future for the treatment of genetic kidney diseases	181
Title Page	162
Proximal-tubule molecular relay from early Protein diaphanous homolog 1 to late Rho-associated protein kinase 1 regulates kidney function in obesity-induced kidney damage	151
Editorial Board	148
Editorial Board	144
Subscription Information	139
Including APOL1 alleles and ancestry adjustments improve a genome-wide polygenic CKD score	135
In this issue	126
Editorial Board	120
Should we consider calcimimetics as a therapeutic option for nephrotic syndrome?	106
A single approach to targeting transferrin receptor 2 corrects iron and erythropoietic defects in murine models of anemia of inflammation and chronic kidney disease	100
The authors reply:	99
Improving frozen section evaluation of procurement donor kidney biopsies and reducing the discard rate: a promising role for artificial intelligence	96
Neutrophil gelatinase-associated lipocalin is elevated in children with acute kidney injury and sickle cell anemia, and predicts mortality	96
Seeing through the density of dense deposit disease	95
Unexpected metabolic effects of sodium-glucose cotransporter 2 inhibitors	95

Enhancing kidney organoid maturity with inducible vascularization: another step forward for in vitro modeling	93
Unlocking the full potential of human pluripotent stem cell–derived kidney organoids through bioengineering	93
On the relevance of thrombomodulin variants in atypical hemolytic uremic syndrome	89
Endothelial but not systemic ferroptosis inhibition protects from antineutrophil cytoplasmic antibody–induced crescentic glomerulonephritis	85
New advances in endocrine hypertension: from genes to biomarkers	83
Trans-ethnic genome-wide association study of blood metabolites in the Chronic Renal Insufficiency Cohort (CRIC) study	83
Blood pressure adaptation in vertebrates: comparative biology	81
Multi-omics and imaging mass cytometry characterization of human kidneys to identify pathways and phenotypes associated with impaired kidney function	80
Kidney protective mechanisms of SGLT2 inhibitors: evidence for a hemodynamic effect	80
Challenges in the development of novel methodologies for measuring glomerular filtration rate	79
Monoclonal immunoglobulin crystalline nephropathies	77
The single-cell landscape of the human vein after arteriovenous fistula creation and implications for maturation failure	75
Epigenetic alterations and memory: key players in the development/progression of chronic kidney disease promoted by acute kidney injury and diabetes	74
Function follows form: the quest for the best prognostic imaging biomarker in ADPKD	71
Glomerular-tubular crosstalk via cold shock Y-box binding protein-1 in the kidney	71
Women and kidney health: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference	70
Dysfunction of the circadian clock in the kidney tubule leads to enhanced kidney gluconeogenesis and exacerbated hyperglycemia in diabetes	67
Kidney supportive care: every nephrologist’s business	66
Ttc21b deficiency attenuates autosomal dominant polycystic kidney disease in a kidney tubular- and maturation-dependent manner	66
Caloric restriction reduces the pro-inflammatory eicosanoid 20-hydroxyeicosatetraenoic acid to protect from acute kidney injury	64
Giving monocytes their due: how CD47–SIRP-α reframes allograft rejection	62
Rationale and design of the Nephrotic Syndrome Study Network (NEPTUNE) Match in glomerular diseases: designing the right trial for the right patient, today	61
Expanding the perspective: addressing additional limitations in cardiovascular risk assessment of immunosuppressive therapies	60
Identifying strategies for disseminating research to patients with chronic kidney disease and caregivers: a workshop report	60
Mitochondrial ROS connects P2X7-mediated Ca2+ influx with IL-1α release by monocytes upon chronic tissue damage	59
Corrigendum to “Executive summary of the KDIGO 2024 Clinical Practice Guideline for the Management of ANCA–Associated Vasculitis.” Kidney International 2024;105(3):447–449	59
Corrigendum to “Effects of dialysate potassium concentration of 3.0 mmol/l with sodium zirconium cyclosilicate on dialysis-free days versus dialysate potassium concentration of 2.0 mmol/l alone on rat	59
Protein kinase ROCK1 activates mitochondrial fission linking to oxidative stress and muscle atrophy	58
Editorial Board	57
Erdheim-Chester disease: hairy kidney and coated aorta	56
Improving the management of chronic kidney disease in primary care by enhancing laboratory reports with additional information and follow-up procedures	56
To do or not to do—genetic testing for autosomal dominant polycystic kidney disease in children and adolescents	55
A genomic deep field view of hypertension	55
First do no harm: systemic glucocorticoids should not be used for the treatment of progressive IgA nephropathy	55
Renal artery microaneurysms in antineutrophil cytoplasmic antibody–associated vasculitis	53
Acknowledgment of reviewers	53
The authors reply:	53
The T-cell environment: may the regulatory force be with you	52
Caution in interpreting anti-nephrin antibodies as causal in nephrotic syndrome	52
Urine: from waste to fertilizer	52
Letter to the Editor	50
Crystal-induced colitis	50
Kidney traits on repeat—the role of MUC1 VNTR	50
In This Issue	49
Editorial Board	49
Editorial Board	48
RORing toward immunoregulation in glomerulonephritis?	48
Immunoaging within the kidney via injury-associated tertiary lymphoid tissue	48
Response to the commentary “Modeling pulse wave velocity trajectories—challenges, opportunities, and pitfalls”	47
The authors reply	47

Erratum to Kudose S, Lipton M, Jain NG, D’Agati VD. “Valproic acid–associated proximal tubulopathy.” Kidney Int. 2022;101:653	46
Tumor-induced osteomalacia	46
Subscription Information	46
Impact of study design on vaccine effectiveness estimates of 2 mRNA COVID-19 vaccine doses in patients with stage 5 chronic kidney disease	45
The Case | Is this hemolytic uremic syndrome?	44
The Case | A patient with autosomal dominant polycystic kidney disease with an atypical kidney magnetic resonance image	44
journal club	44
The authors reply	44
The Case | Neonatal seizures and tubular dysfunction in childhood: joining the dots!	44
Subscription Information	44
The Case | A patient with skin rash, monoclonal gammopathy, and proteinuria	44
Felzartamab: a magic bullet to treat microvascular rejection?	44
Optimizing symptom management in people with kidney failure	43
Kidney transplantation and hyperbaric oxygen treatment for calciphylaxis	43
Seeing the light (chains): a paradigm shift in PGNMID	43
Mutations in tumor suppressor genes Vhl and Rassf1a cause DNA damage, chromosomal instability and induce gene expression changes characteristic of clear cell renal cell carcinoma	43
Sexual dimorphism of age and nephron segment specific gene expression in mouse kidneys: insights from multi-omic and spatial analysis	42
Machine learning does not outperform traditional statistical modelling for kidney allograft failure prediction	42
Dynamically visualizing profibrotic maladaptive repair after acute kidney injury by fibroblast activation protein imaging	42
The prevention and management of chronic kidney disease among patients with metabolic syndrome	42
Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model	42
Hypoxia hits APOL1 in the kidney	41
The randomized DIALIZE-Outcomes trial evaluated sodium zirconium cyclosilicate in hemodialysis	41
Renal Pathology Society/International Kidney and Monoclonal Gammopathy Research Group consensus on pathologic definitions and terminology of monoclonal gammopathy–associated kidney lesions	40
The transcription factor ATF4 mediates endoplasmic reticulum stress-related podocyte injury and slit diaphragm defects	40
Repression of peroxisome proliferation-activated receptor γ coactivator-1α by p53 after kidney injury promotes mitochondrial damage and maladaptive kidney repair	39
Kidney-resident macrophages limit toxin-induced inflammation through their hallmark functions	39
Cinacalcet in focal segmental glomerular sclerosis: a case report	39
in this issue	39
Title Page	37
Age and memory B cells at baseline are associated with risk of relapse and memory B-cell reappearance following anti-CD20 treatment in pediatric frequently-relapsing/steroid-dependent nephrotic syndro	37
Complement activation and effector pathways in membranous nephropathy	37
Cutaneous histoplasmosis in a patient with a kidney transplant	36
The authors reply	36
journal club	36
Cardiovascular disease as a risk factor for frailty in dialysis patients	36
Editorial Board	36
Discrepancies between transcutaneous and estimated glomerular filtration rates in rats	36
Table of Contents	35
Do macrophages inhibit or promote atheroma plaque calcification and stability?	35
in this issue	35
Fragmented futures: ROCK1 drives mitochondrial fission and muscle loss in CKD	35
The authors reply:	35
Subscription Information	35
The relationship between imaging features of diffusion-weighted imaging and prognosis of chronic kidney disease	34
The Case | Acute kidney injury and a facial lesion	34
Initiation of maintenance dialysis: back to the future	34
Modeling pulse wave velocity trajectories—challenges, opportunities, and pitfalls	34
Editorial Board	34
Deciphering missense coding variants with AlphaMissense	33
Estimating glomerular filtration rate from serum creatinine concentration in children with augmented renal clearance: all formulas are equivocal, but some are more equivocal than others	33
Table of Contents	33
Integrating basic science with translational research: the 13th International Podocyte Conference 2021	33
From the field to the assembly hall: the history of the kidney health resolution	32
Endemic rise in cases of acute kidney injury in children in Indonesia and Gambia: what is the likely culprit and why?	32
Berger disease redux	32
A paired-kidney allocation study found superior survival with HLA-DR compatible kidney transplants in the Eurotransplant Senior Program	32
Subscription Information	32
Subscription Information	32
Advancing proteomics in nephrology: unraveling causal pathways and therapeutic targets	31
Peripheral blood smear as a diagnostic clue to type I cryoglobulinemia	31
Table of Contents	31
Effective management of chyluria with retrograde thoracic duct catheterization and embolization	31
The authors reply	31
Good and evil, more reasons to study UPR	31
Apixaban for stroke prevention in hemodialysis patients with nonvalvular atrial fibrillation	31
Editorial Board	31
Female sex hormones inversely regulate acute kidney disease susceptibility throughout life	30
Podocyte protease activated receptor 1 stimulation in mice produces focal segmental glomerulosclerosis mirroring human disease signaling events	30
High-dimensional mass cytometry identified circulating natural killer T-cell subsets associated with protection from cytomegalovirus infection in kidney transplant recipients	30
The lupus nephritis management renaissance	30
Strategies for the development of sodium-glucose cotransporter-2 inhibitors for kidney protection in pediatric chronic kidney disease: proceedings of a workshop meeting in July 2023	30
Implementing the commitments of the WHO kidney health resolution: initial steps in 3 diverse settings	30
Phosphoenolpyruvate carboxykinase 1-mediated cataplerosis is required to maintain mitochondrial fitness and to avoid kidney disease progression	30
Findings from 4C-T Study demonstrate an increased cardiovascular burden in girls with end stage kidney disease and kidney transplantation	30
Kidney biopsy in acute kidney injury: increase insight or preserve the status quo?	29
Molecular profiling of kidney compartments from serial biopsies differentiate treatment responders from non-responders in lupus nephritis	29
National and international kidney failure registries: characteristics, commonalities, and contrasts	29
Anti-nephrin autoantibodies: novel predictors of post-transplant recurrence of focal segmental glomerular sclerosis	29
Enhancer and super-enhancer landscape in polycystic kidney disease	29

The nucleotide-sensing Toll-Like Receptor 9/Toll-Like Receptor 7 system is a potential therapeutic target for IgA nephropathy	29
When YAP is hyperactivated in podocytes, it persistently “yaps,” disrupting the quiescence of neighboring glomerular cells	29
Lineage tracing analysis defines erythropoietin-producing cells as a distinct subpopulation of resident fibroblasts with unique behaviors	28
Critical Role of histone deacetylase 3 in the regulation of kidney inflammation and fibrosis	28
Nephrotic syndrome genomic discovery in the Mass General Brigham Biobank identifies monoallelic MEFV variants as a risk factor for focal segmental glomerulosclerosis	28
New-onset class III lupus nephritis with multi-organ involvement after COVID-19 vaccination	28
Executive summary of the KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease: known knowns and known unknowns	28
Insulin-like growth factor binding protein 7 promotes acute kidney injury by alleviating poly ADP ribose polymerase 1 degradation	28
A pragmatic, open-label, randomized controlled trial of Plasma-Lyte-148 versus standard intravenous fluids in children receiving kidney transplants (PLUTO)	28
Dried blood spot testing versus standard i.v. sampling for GFR measurement with iohexol or 99mTc-DTPA	28
Risk stratification of metabolic disorder–associated kidney disease	28
In this Issue	27
in this issue	27
In remembrance of Gary Striker, MD (1934–2024)	27
ER stress and slit diaphragms: is there a connection?	27
Expression of concern from the KI Editors: “Apolipoprotein-1 risk variants and associated kidney phenotypes in an adult HIV cohort in Nigeria” [Kidney International, July 2021, Pages 146–154] and “APO	27
Subscription Information	27
Using prediction models to improve care and communicate risk: updated modeling for children with IgA nephropathy	27
Table of Contents	27
The authors reply	27
Has APOL1 kidney disease treatment been hiding in plain sight?	27
Asymptomatic migration of a peritoneal dialysis catheter	27
Non-canonical Wnt/calcium signaling is protective against podocyte injury and glomerulosclerosis	26
The authors reply:	26
Series introduction: drug repurposing for kidney diseases	26
Table of Contents	26
Uremia-associated fibrinous pericarditis	26
Subscription Information	26
Antioxidant nanozymes for prevention of diseased kidney from failure	26
The Case | Acute neck swelling in a patient undergoing dialysis	26
Protective mechanisms harnessing against injurious heme and preventing kidney damage in STEC-HUS: toward new therapies?	26
The authors reply	25
Valproic acid–associated proximal tubulopathy	25
in this issue	25
The authors reply	25
The Case | Dark dialysate after colonoscopy	25
Myeloid-derived growth factor deficiency exacerbates mitotic catastrophe of podocytes in glomerular disease	25
Editorial Board	25
Is bone histomorphometry required for assessment of renal osteodystrophy in clinical practice?	25
Acquired cutis laxa from heavy chain deposition disease	25
The authors reply:	25
Progress, challenges, and pragmatic concessions in predicting relative risk of kidney survival in ARPKD	25
journal club	25
The Case | An unusual cause of proteinuria in a kidney transplant recipient	25
Subscription Information	25
Leukocyte immunoglobulin like receptor B3 (LILRB3) and allograft survival: can precision medicine target health disparities?	25
Executive summary of the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children	24
Kidney targeting of formoterol containing polymeric nanoparticles improves recovery from ischemia reperfusion-induced acute kidney injury in mice	24
A multiomic resource to interpret genetic associations with kidney function	24
Unfolding the potential—chemical chaperones in Alport syndrome	24
Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier	24
Glomerular filtration rate estimation in transgender and gender-diverse adults using gender-affirming hormone therapy: an exploratory cross-sectional study	24
A polygenic score for reduced kidney function and adverse outcomes in a cohort with chronic kidney disease	24
Reevaluating principal component analysis: advocating for nonlinear and nonparametric methods in multi-omics data analysis	24
A genetically inducible endothelial niche enables vascularization of human kidney organoids with multilineage maturation and emergence of renin expressing cells	23
Equity in evidence: overcoming barriers to kidney trials in low-resource settings	23
Conservative kidney management and kidney supportive care: core components of integrated care for people with kidney failure	23
Mendelian randomization for nephrologists	23
A national registry study evaluated the landscape of kidney transplantation among presumed unauthorized immigrants in the United States	23
Anti-nephrin antibodies guide living donor kidney transplantation in a pediatric patient with primary focal segmental glomerular sclerosis	23
An introduction to realist evaluation and synthesis for kidney research	23
Precision nephrology identified tumor necrosis factor activation variability in minimal change disease and focal segmental glomerulosclerosis	23
Are your kidneys Ok? Detect early to protect kidney health	23
Differing sensitivities to angiotensin converting enzyme inhibition of kidney disease mediated by APOL1 high-risk variants G1 and G2	23
KDIGO 2025 clinical practice guideline for the evaluation, management, and treatment of autosomal dominant polycystic kidney disease (ADPKD): executive summary	23
Table of Contents	23
A novel model of nephrotic syndrome results from a point mutation in Lama5 and is modified by genetic background	23
Title Page	22
Nephronophthisis-associated ciliopathy with brachydactyly, medullary cysts, and chronic kidney disease	22
journal club	22
Insights from ADPedKD, ERKReg and RaDaR registries provide a multi-national perspective on the presentation of childhood autosomal dominant polycystic kidney disease in high- and middle-income countri	22
Advanced optical imaging reveals preferred spatial orientation of podocyte processes along the axis of glomerular capillaries	22
In memoriam: George L. Bakris, MD, 1952–2024	22
Corrigendum to Cai J, Liu Z, Huang X, et al. The deacetylase sirtuin 6 protects against kidney fibrosis by epigenetically blocking β-catenin target gene expression Kidney Int. 2020;97:106–118	22
Hemolysis is associated with altered heparan sulfate of the endothelial glycocalyx and with local complement activation in thrombotic microangiopathies	22
Breakthrough omicron COVID-19 infections in patients receiving the REGEN-Cov antibody combination	22
in this issue	22
Bile cast nephropathy after sinusoidal obstruction syndrome	22
Editorial Board	22
Melanocortin 5 receptor signaling protects against podocyte injury in proteinuric glomerulopathies	22
Subscription Information	21
Recognizing the true face of noninfectious cryoglobulinemic glomerulonephritis	21
Subscription Information	21
in this issue	21
Avoiding arrythmias by personalizing the dialysate concentration: a case for precision medicine in patients on dialysis	21
Subscription Information	21
The Case | A rare donor-derived cause of delayed graft function	21
in this issue	21
Targeting angiopoietin-2 as a novel treatment option for kidney fibrosis	21
Unique problems for the design of the first trials of transplanting porcine kidneys into humans	21
Editorial Board	21
Doxorubicin-associated red-colored dialysate	21
Stronger together: the power of cross-organ data sets for improved allograft study outcomes	21
Suppression of aldehyde dehydrogenase 2 in kidney proximal tubules contributes to kidney fibrosis through Transforming Growth Factor-β signaling	21
Population-based reference values for kidney function and kidney function decline in 25- to 95-year-old Germans without and with diabetes	20