Drug Metabolism and disPosition

Papers
(The H4-Index of Drug Metabolism and disPosition is 24. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Editorial Board65
Editorial Board61
Table of Contents59
Evaluation of Drug-Drug Interactions via Inhibition of Hydrolases by Orlistat, an Anti-Obesity Drug56
CYP3A4 and CYP3A5 Expression is Regulated by C YP3A4*1G in CRISPR/Cas9-Edited HepG2 Cells55
A Comprehensive Evaluation of the Effects of RNA-Editing Proteins ADAR and ADARB1 on the Expression of the Drug-Metabolizing Enzymes in HepaRG Cells54
Predictive Performance of Physiologically Based Pharmacokinetic Modelling of Beta-Lactam Antibiotic Concentrations in Adipose, Bone, and Muscle Tissues46
Pharmacokinetic insights of onradivir in influenza treatment to inform pediatric dosing selection in clinical trial40
Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs38
Combining the novel all-human co-cultured hepatocytes system with physiologically based pharmacokinetic modeling to assess the translatability of cytochrome P450 and uridine 5′-diphospho-glucuronosylt37
Early Prediction and Impact Assessment of CYP3A4-Related Drug-Drug Interactions for Small-Molecule Anticancer Drugs Using Human-CYP3A4-Transgenic Mouse Models37
Application of preclinical absorption, distribution, metabolism, elimination in vitro techniques for the characterization and compound library optimization of novel antibiotic gallium salophen36
Epigenetic Activation of Cytochrome P450 1A2 Sensitizes Hepatocellular Carcinoma Cells to Sorafenib35
The role of cytochrome P450 and gut microbiome in drug metabolism: Insights into Parkinson disease treatment32
Quantitative Analysis of mRNA and Protein Expression Levels of Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoforms in the Human Intestine32
Ketone reduction drives major circulating metabolites of GDC-8264 in humans28
Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters28
Advances in organ-on-chip for drug transporter study: Key insights and hurdles27
Cytochrome P450 Enzymes as Drug Targets in Human Disease26
Population pharmacokinetic analysis of onradivir to support dosing recommendations in elderly adults with influenza26
Inhibitory effects of Δ8-tetrahydrocannabinol on major hepatic cytochrome P450 enzymes and implications for drug disposition25
Synergistic hepatotoxicity of azithromycin and acetaminophen involves liver X receptor α–mediated metabolic dysregulation and endoplasmic reticulum stress25
Gut microbial resistance and metabolism of selective serotonin reuptake inhibitors drive multidrug resistance and contribute to antidepressant tachyphylaxis24
Quantitative Proteomics for Translational Pharmacology and Precision Medicine: State of The Art and Future Outlook24
Absorption, metabolism, and excretion of single dose oral [14C]camizestrant in healthy human female participants24
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