OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacology Biochemistry and Behavior is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Switching from menthol to non-menthol cigarettes does not impact acute responses to intravenous nicotine	143
Editorial Board	70
Early-life stress of limited bedding/nesting material induced recognition memory loss and decreased hippocampal VGluT1 and nectin3 levels in aged male mice	47
Unique effects of nicotine across the lifespan	46
D-cycloserine is not susceptible to self-administration using an intravenous self-administration model in male ketamine-habituated Sprague-Dawley rats	43
Long- vs short-access cocaine alters behavioral inhibition for cocaine in male rats	38
The synthetic cannabinoid WIN 55,212-2 attenuates cognitive and motor deficits and reduces amyloid load in 5XFAD Alzheimer mice	38
Dusting off old blueprints: Is it time to reconsider metabotropic glutamate receptor 2 for therapeutic drug development?	36
Venlafaxine treatment is associated with improved mood, but not decreased cocaine self-administration, in depressed people who use cocaine	29
Biochemical challenges for testing novel anti-panic drugs in humans	29
Activation of NOS-cGMP pathways promotes stress-induced sensitization of behavioral responses in zebrafish	28
The anxiolytic effects of cannabinoids: A comprehensive review	27
Therapeutically targeting the consequences of HIV-1-associated gastrointestinal dysbiosis: Implications for neurocognitive and affective alterations	23
Early adversity as the prototype gene × environment interaction in mental disorders?	22
Efficacy of ketamine versus esketamine in the treatment of perioperative depression: A review	22
Effects of neonatal dopaminergic lesion on oral cocaine self-administration in rats: Higher female vulnerability to cocaine consumption	21
Do greater levels of in-cage waking inactivity in laboratory mice reflect a spontaneous depression-like symptom? A pharmacological investigation	21
The 5-HT1A receptor antagonist WAY-100635 decreases motor/exploratory behaviors and nigrostriatal and mesolimbocortical dopamine D2/3 receptor binding in adult rats	21
Modafinil acquires reinforcing effects when combined with citalopram	21
A spotlight on HCV and SARS-CoV-2 co-infection and brain function	20
Editorial Board	20
Desvenlafaxine with mindfulness-based cognitive therapy reduces Hamilton anxiety scores compared to escitalopram with mindfulness-based cognitive therapy in treatment-resistant generalized anxiety dis	20
Lifelong outcomes and effects on brain and behavior following childhood maltreatment and early life stress: A primer to inform future research	20
Modulation of circuit oscillations in the rat anterior cingulate cortex (ACC) in vitro by mGlu2 metabotropic glutamate receptors and alleviation of the effects of phencyclidine-induced NMDA-receptor h	19
Editorial Board	18

Editorial Board	18
Editorial Board	18
Opiophobia and the tragedy of needless pain: A call for education and balance	18
The romantic age of pharmacological science	18
Editorial Board	16
The role of mGlu2/3 receptor antagonists in the enhancement of the antidepressant-like effect of ketamine	16
Editorial Board	16
Editorial Board	16
Mirtazapine-induced decrease in cocaine sensitization is enhanced by environmental enrichment in rats	16
Editorial Board	15
Editorial Board	15
Retigabine promotes ketamine's antidepressant effect in the forced swim test in male and female C57BL/6J mice	14
Acute MK-801 increases measures of both sign-tracking and goal-tracking in male Sprague-Dawley rats	14
Impulsivity and aggression in alcohol withdrawal syndrome is modulated by the interaction of ZNF804A and mTOR polymorphism	14
Gender differences in the relationship between nicotine exposure and symptoms of depression	14
N-Substituted-3-alkoxy-derivatives of dextromethorphan are functional NMDA receptor antagonists in vivo: Evidence from an NMDA-induced seizure model in rats	14
Blocking the ErbB pathway during adolescence affects the induction of anxiety-like behavior in young adult maternal immune activation offspring	14
An intergenerational lifespan perspective on the neuroscience of prenatal substance exposure	13
Prepubertal methylphenidate leads to sex-dependent differences in probabilistic discounting	13
A pilot study examining the relationship between chronic heroin use and telomere length among individuals of African ancestry	13
Enhancement of cue-induced reinstatement of alcohol seeking by acute total sleep restriction in male Wistar rats	13
Elevated customary alcohol consumption attenuates opioid effects	13
Sex differences in serotonergic control of rat social behaviour	13
Modulation of mGlu5 improves sensorimotor gating deficits in rats neonatally treated with quinpirole through changes in dopamine D2 signaling	12
Novelty preferences and cocaine-associated cues influence regions associated with the salience network in juvenile female rats	12
Chronic inflammatory pain reduces fentanyl intake during early acquisition of fentanyl self-administration, but does not change motivation to take fentanyl in male and female rats	12
Hippocampus-sensitive and striatum-sensitive learning one month after morphine or cocaine exposure in male rats	12
The interaction effects between opioidergic and D1-like dopamine receptors in the nucleus accumbens on pain-related behaviors in the animal model of acute pain	12
Untapped endocannabinoid pharmacological targets: Pipe dream or pipeline?	12
Sex, drugs, and zebrafish: Acute exposure to anxiety-modulating compounds in a modified novel tank dive test	11
Simultaneous use of venlafaxine and calcium channel blockers on tolerance to morphine: The role of mitochondrial damage and oxidative stress in the brain	11
Physical activity as a promoter of stress resilience: An analysis of behavioral effects and brain connectivity with cytochrome c-oxidase activity in adult male Wistar rats	11
Group I mGluRs positive allosteric modulators improved schizophrenia-related behavioral and molecular deficits in the Poly I:C rat model	11
Naltrexone-bupropion combinations do not affect cocaine self-administration in humans	11
Chronic exposure of female mice to selective serotonin reuptake inhibitors during lactation induces vocal behavior deficits in pre-weaned offspring	11
Maternal fluoxetine impairs synaptic transmission and plasticity in the medial prefrontal cortex and alters the structure and function of dorsal raphe nucleus neurons in offspring mice	11
Lower distress intolerance is associated with higher glutathione levels in adolescent cannabis users	11
mGlu2 and mGlu3 receptor negative allosteric modulators attenuate the interoceptive effects of alcohol in male and female rats	11
2,5-Dimethoxy-4-iodoamphetamine and altanserin induce region-specific shifts in dopamine and serotonin metabolization pathways in the rat brain	11
Role of group II metabotropic glutamate receptors in ketamine's antidepressant actions	11
Gestational environmental enrichment prevents chronic social stress induced anxiety- and ethanol-related behaviors in offspring	11
Discriminative stimulus and reinforcing effects of diclazepam in rodents	10
Distinctively lower DISC1 mRNA levels in patients with schizophrenia, especially in those with higher positive, negative, and depressive symptoms	10
Cannabidiol attenuates prepulse inhibition disruption by facilitating TRPV1 and 5-HT1A receptor-mediated neurotransmission	10
Time-dependent effects of nicotine on reversal of dizocilpine-induced attentional impairment in female rats	10
Acute stress induces different changes on the expression of CB1 receptors in the hippocampus of two lines of male rats differing in their response to stressors	10
TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats	10
Incentive motivation for palatable food blocked by intra-accumbens melanin-concentrating hormone (MCH) receptor-1 antagonist in female rats	10
The intersection of empathy and addiction	9
Acute cannabidiol treatment attenuates ethanol-induced place preference and reduces aggressivity in group-housed male rats	9

Chronic levetiracetam (Keppra®) treatment increases the reinforcing strength of cocaine in rhesus monkeys	9
Stimulation of lateral parabrachial (LPB) to central amygdala (CeA) pituitary adenylate cyclase-activating polypeptide (PACAP) neurons induces anxiety-like behavior and mechanical allodynia	9
Cholesterol metabolism pathway in autism spectrum disorder: From animal models to clinical observations	9
Kappa-opioid receptor antagonism in the nucleus accumbens shell distinguishes escalated alcohol consumption and negative affective-like behavior from physiological withdrawal in alcohol-dependence	9
Adolescent drug addiction	9
Glucocorticoid- β-adrenoceptors interactions in the infralimbic cortex in acquisition and consolidation of auditory fear memory extinction in rats	9
Long-term administration of paroxetine increases cortical EEG beta and gamma band activities in healthy awake rats	8
Confronting the challenge of failed translation in medications development for substance use disorders	8
Sleep and alertness disturbance and substance use disorders: A bi-directional relation	8
Psychological pain and opioid receptors: Reward downshift is disrupted when tested in a context signaling morphine	8
ANXIOLYTICS: Introduction to a special issue celebrating 50 years of Pharmacology, Biochemistry and Behavior	8
Molecular signature underlying (R)-ketamine rapid antidepressant response on anhedonic-like behavior induced by sustained exposure to stress	8
A systematic review of cannabidiol trials in neurodevelopmental disorders	8
Object recognition and Morris water maze to detect cognitive impairment from mild hippocampal damage in rats: A reflection based on the literature and experience	8
Fluoxetine treatment reverses chronic stress-induced promotion on Fk506-binding protein 5 expression and multiple effects on glucocorticoid receptor phosphorylation in the paraventricular nucleus of m	8
Editorial Board	8
Inflammation and early life stress: An updated review of childhood trauma and inflammatory markers in adulthood	8
5-HT2C agonists and antagonists block different components of behavioral responses to potential, distal, and proximal threat in zebrafish	8
Danavorexton, a selective orexin 2 receptor agonist, provides a symptomatic improvement in a narcolepsy mouse model	7
Dysregulation of kappa opioid receptor neuromodulation of lateral habenula synaptic function following a repetitive mild traumatic brain injury	7
Estradiol administration increases anxiety-like behavior following chronic escalating morphine administration in hormone-replaced ovariectomized female rats	7
Mirtazapine attenuates the cocaine-induced locomotor sensitization in male and female C57BL/6J and BALBA/cJ mouse	7
Contrasting effects of d-amphetamine and atomoxetine on measures of impulsive action and choice	7
Interleukin-1β-induced inflammation and acetaminophen during infancy: Distinct and interactive effects on social-emotional and repetitive behavior in C57BL/6J mice	7
Differential reductions in alcohol consumption and cue-induced alcohol-seeking behavior following mGlu5 receptor inhibition in the prelimbic vs. infralimbic subregions of the rat prefrontal cortex	7
Corrigendum to “Sex differences in aripiprazole sensitization from adolescence to adulthood” [Pharmacol. Biochem. Behav. 156 (2017) 39–47]	7
The associations between cognitive functions and TSNAX genetic variations in patients with schizophrenia	7
Inflammation and Connexin 43 profiles in the prefrontal cortex are relevant to stress susceptibility and resilience in mice	7
Purified cannabidiol leads to improvement of severe treatment-resistant behavioral symptoms in children with autism spectrum disorder	7
Fluoxetine attenuates the anxiolytic effects of the probiotic VSL#3 in a stress-vulnerable genetic line of aves in the chick social-separation stress test, a dual screening assay	7
Editorial Board	7
Photobiomodulation using an 830-nm laser alleviates hippocampal reactive gliosis and cognitive dysfunction in a mouse model of adolescent chronic alcohol exposure	7
Haloperidol and methylphenidate alter motor behavior and responses to conditioned fear of Carioca Low-conditioned Freezing rats	6
Manganese-induced hyperactivity and dopaminergic dysfunction depend on age, sex and YAC128 genotype	6
CXCR2 antagonist SB332235 mitigates deficits in social behavior and dysregulation of Th1/Th22 and T regulatory cell-related transcription factor signaling in male BTBR T+ Itpr3tf/J mouse model of auti	6
Negative allosteric modulation of metabotropic glutamate receptor 5 attenuates alcohol self-administration in baboons	6
Acute caffeine ingestion improves 3-km run performance, cognitive function, and psychological state of young recreational runners	6
Metoprine, a histamine N-methyltransferase inhibitor, attenuates methamphetamine-induced hyperlocomotion via activation of histaminergic neurotransmission in mice	6
Psychologically traumatic stress inducing redox – inflammation interplay; which comes first?	6
Editorial Board	6
Editorial Board	6
Editorial Board	6
Sex-dependent and long-lasting effects of adolescent sleep deprivation on social behaviors in adult mice	6
iTat transgenic mice exhibit hyper-locomotion in the behavioral pattern monitor after chronic exposure to methamphetamine but are unaffected by Tat expression	6
Pre-mating administration of theophylline could prevent the transgenerational effects of maternal morphine dependence on offspring anxiety behavior: The role of dopamine receptors	6
Transmission of the adverse consequences of childhood maltreatment across generations: Focus on gestational biology	6
The importance of examining sex differences in animal models validated to induce an addiction-like phenotype	6
Editorial Board	6
Age-dependent effects of embryonic ethanol exposure on anxiety-like behaviours in young zebrafish: A genotype comparison study	6
Attenuation of nicotine-induced rewarding and antidepressant-like effects in male and female mice lacking regulator of G-protein signaling 2	6
Editorial Board	6
(2R,6R)-hydroxynorketamine alleviates PTSD-like endophenotypes by regulating the PI3K/AKT signaling pathway in rats	6
REM sleep deprivation before extinction or reinstatement alters methamphetamine reward memory via D1-like dopamine receptors	6
Ethanol pre-exposure differentially impacts the rewarding and aversive effects of α-pyrrolidinopentiophenone (α-PVP): Implications for drug use and abuse	6
The endowment effect and temporal discounting of drug and non-drug commodities	6
Acute caffeine differently affects risk-taking and the expression of BDNF and of adenosine and opioid receptors in rats with high or low anxiety-like behavior	6
Vapor exposure to Δ9-tetrahydrocannabinol (THC) slows locomotion of the Maine lobster (Homarus americanus)	6
Epigenetic regulation of metabotropic glutamate 2/3 receptors: Potential role for ultra-resistant schizophrenia?	6
Advances in translating mGlu2 and mGlu3 receptor selective allosteric modulators as breakthrough treatments for affective disorders and alcohol use disorder	5
Substance use disorder is the outcome of deviant socialization: A prospective investigation spanning childhood to adulthood	5
Escalating caffeine dose-dependently increases alcohol consumption in adult male, but not female, C57BL/6J mice	5
mGlu2/3 receptor agonist (LY354740) in anxiety	5
Juvenile chronic social defeat stress reduces prosocial behavior in adult male mice	5
Environmental enrichment enhances the antidepressant effect of ketamine and ameliorates spatial memory deficits in adult rats	5
Deciphering the gut microbiota's (Coprococcus and Subdoligranulum) impact on depression: Network pharmacology and molecular dynamics simulation	5
Serotonergic inhibition of responding for conditioned but not primary reinforcers	5
Temporary inactivation of the infralimbic cortex impairs while the blockade of its dopamine D2 receptors enhances auditory fear extinction in rats	5
Concurrent measures of impulsive action and choice are partially related and differentially modulated by dopamine D1- and D2-like receptors in a rat model of impulsivity	5
A social contextual review of the effects of alcohol on emotion	5
Sex differences in the elevated plus-maze test and large open field test in adult Wistar rats	5
Methylphenidate and atomoxetine treatment negatively affect physical growth indexes of school-age children and adolescents with attention-deficit/hyperactivity disorder	5
Enhanced antidepressant-like effects of a delta opioid receptor agonist, SNC80, in rats under inflammatory pain	5
Pramipexole decreases allodynia and hyperalgesia via NF-κB in astrocytes in rats with Parkinson's disease	5
Protein kinases in natural versus drug reward	5
Caffeic acid differentially modulates behavior and neurochemicals in chronic unpredictable mild stress and dexamethasone induced models of depression	5
Unlocking the age-old secrets of reward and substance use	5
Activation of GPR55 attenuates cognitive impairment, oxidative stress, neuroinflammation, and synaptic dysfunction in a streptozotocin-induced Alzheimer's mouse model	5