Journal of Allergy and Clinical Immunology

Article	Citations
News & Notes	262
Editorial Board	218
Reply	210
Reply	206
Dupilumab for chronic spontaneous urticaria—marvelous or meek?	197
Non–IgE-mediated anaphylaxis	189
News & Notes	164
Information for Readers	155
News Beyond Our Pages	154
Recent advances in the immunopathogenesis of severe asthma	154
Imaging eosinophil secretory granules: From storage containers to active, immune responder organelles	153
Corrigendum	147
Somatic mosaicism in genetic errors of immunity	142
NLRC4-associated autoinflammatory disease: Insights from mouse models and somatic variants	135
Examining disparities in biologic therapy initiation: The intersection of race/ethnicity and insurance type	126
Editorial Board	116
Cross-tissue, age-specific flow cytometry reference for immune cells in airway and blood of children	110
CME Calendar-AAAAI	110
Differential T follicular helper cell phenotypes distinguish IgE-mediated milk allergy from eosinophilic esophagitis in children	109
Leptin augments IL-13–induced airway eotaxins and submucosal eosinophilia in obesity-associated asthma	107
Ruxolitinib treatment ameliorates clinical, immunologic, and transcriptomic aberrations in patients with STAT3 gain-of-function disease	106
Identification of bronchial epithelial genes associated with type 2 eosinophilic inflammation in asthma	105
The monogenic landscape of human infectious diseases	105
Early-life microRNA signatures in cord blood associated with allergic rhinitis and asthma development	101
Curation of gene–disease relationships in primary antibody deficiencies using the ClinGen validation framework	99

Sputum short-chain fatty acids, microbiome, inflammation, and mucus plugging in obstructive airway disease	96
Igniting the firestorm: The inflammasome in autoinflammatory syndromes	95
Table of Contents	94
News Beyond Our Pages	94
Cover 1	92
Studies on activation and regulation of the coagulation cascade in chronic rhinosinusitis with nasal polyps	90
Information for Readers	86
Reflections on a half century of mentoring	85
Novel insights on the biology and immunologic effects of histamine: A road map for allergists and mast cell biologists	84
Coronavirus disease 2019 (COVID-19) in children: Evolving epidemiology, immunology, symptoms, diagnostics, treatment, post–COVID-19 conditions, prevention strategies, and future directions	84
ICOSL, OX40L, and CD30L control persistence of asthmatic CD4 tissue-resident memory CD4 T cells	83
Reply	83
BNT162b2 COVID-19 vaccination elicits the expansion of CD16+CD8+ T cells endowed with natural killer cell features	83
Loss of Bach2 in T cells causes prolonged allergic inflammation through accumulation of effector T cells and disruption of epidermal barrier	82
Single-cell immunoprofiling after immunotherapy for allergic rhinitis reveals functional suppression of pathogenic TH2 cells and clonal conversion	81
Cover 1	81
Inflammatory heterogeneity in aspirin-exacerbated respiratory disease	80
Food insecurity and allergic diseases: A call to collective action	80
Altered leukocyte subsets and immune proteome indicate proinflammatory mechanisms in mastocytosis	80
Enteric nervous system and intestinal epithelial regulation of the gut-brain axis	79
News beyond our pages	79
Circulating innate lymphoid cells (cILCs): Unconventional lymphocytes with hidden talents	79
Brief Overview of This Month's JACI	78
Editorial Board	77
A Special Thank-You to Our Reviewers	77
Continuing Medical Education Calendar	77
In lasting tribute: Dr Hans Bisgaard, January 24, 1955, to September 8, 2022	76
Editorial Board	75
Dupilumab Reduces Biomarkers of Type 2 Inflammation in Adult and Adolescent Patients With Eosinophilic Esophagitis: Results From Parts A and C of a Three-Part, Phase 3 LIBERTY EoE TREET Study	75
Late-onset enteric virus infection associated with hepatitis (EVAH) in transplanted SCID patients	75
Interactions between skin-resident dendritic and Langerhans cells and pain-sensing neurons	74
CME Calendar-AAAAI	73
Sensory neuroimmune signaling in the pathogenesis of Stevens-Johnson syndrome and toxic epidermal necrolysis	72
Retraction notice to Neighborhood-level variability in asthma-related emergency department visits in Central Texas	72
Continuing Medical Education Calendar	71
Editorial Board	71
Continuing Medical Education Calendar	70
Innate (learned) memory	69
Homozygous DBF4 mutation as a cause of severe congenital neutropenia	69
Treating asthma in the time of COVID	68
A gain-of-function variation in PLCG1 causes a new immune dysregulation disease	68
Hypogammaglobulinemia and immune dysregulation—not just 2 sides of a coin	67
Dual inhibition of airway inflammation and fibrosis by common β cytokine receptor blockade	67
Ssu72 regulates alveolar macrophage development and allergic airway inflammation by fine-tuning of GM-CSF receptor signaling	67
Evolving spectrum of adenosine deaminase (ADA) deficiency: Assessing genotype pathogenicity according to expressed ADA activity of 46 variants	66
Chronic rhinosinusitis patients display an aberrant immune cell localization with enhanced S aureus biofilm metabolic activity and biomass	65
Do upper respiratory viruses contribute to racial and ethnic disparities in emergency department visits for asthma?	65
Eosinophil depletion with benralizumab is associated with attenuated mannitol airway hyperresponsiveness in severe uncontrolled eosinophilic asthma	64
CXXC5 variant in an immunodeficient patient with a progressive loss of hematopoietic cells	64
Trial of thromboxane receptor inhibition with ifetroban: TP receptors regulate eicosanoid homeostasis in aspirin-exacerbated respiratory disease	62

Effect of mepolizumab in airway remodeling in patients with late-onset severe asthma with an eosinophilic phenotype	62
Revisiting autoimmune lymphoproliferative syndrome caused by Fas ligand mutations	62
Generation and durability of immune memory in older adults	61
Evolution of epitope-specific IgE and IgG4 antibodies in children enrolled in the LEAP trial	61
Burden of preschool wheeze and progression to asthma in the UK: Population-based cohort 2007 to 2017	61
Interactions between host epigenetics and microbiota: Who does what to whom, when, and why?	61
Abnormal biomarkers predict complex FAS or FADD defects missed by exome sequencing	60
Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation	60
IL-13 and IL-13–induced periostin levels are specifically decreased in patients following endoscopic sinus surgery for chronic rhinosinusitis	60
Validation of the Asthma Severity Scoring System (ASSESS) in the ALLIANCE Cohort	60
Genetic errors of immunity distinguish pediatric nonmalignant lymphoproliferative disorders	60
In lasting tribute: K. Frank Austen, March 14, 1928, to June 23, 2023	60
Asthma and carotid artery plaques	60
Bioactive lipids: Accessible indicators toward improved diagnosis and treatment of asthma	59
Successful treatment of a novel type I interferonopathy due to a de novo PSMB9 gene mutation with a Janus kinase inhibitor	59
Preschool impulse oscillometry predicts active asthma and impaired lung function at school age	59
Asthma and respiratory comorbidities	58
The deubiquitinase CYLD controls protective immunity against helminth infection by regulation of Treg cell plasticity	58
Reply	58
IL-4 receptor alpha signaling alters oral food challenge and immunotherapy outcomes in mice	58
Sharing is caring? Skin microbiome insights into staphylococci in patients with atopic dermatitis and caregivers	58
Protein arginine methyltransferase 1 contributes to the development of allergic rhinitis by promoting the production of epithelial-derived cytokines	57
Impact of a pollution breach at a coke oven factory on asthma control in nearby vulnerable adults	57
Disease-associated mutations in topoisomerase IIβ result in defective NK cells	57
Distinct transcriptomic and metabolomic profiles characterize NSAID-induced urticaria/angioedema patients undergoing aspirin desensitization	57
The climate change hypothesis for the allergy epidemic	56
Immunologic effects of aspirin desensitization and high-dose aspirin therapy in aspirin-exacerbated respiratory disease	55
Nasopharyngeal airway dual-transcriptome of infants with severe bronchiolitis and risk of childhood asthma: A multicenter prospective study	55
Memory-type pathogenic TH2 cells and ILC2s in type 2 allergic inflammation	55
Beyond obesity: The complex relationship between early growth trajectories and later lung function	54
Retinoic acid promotes fibrinolysis and may regulate polyp formation	54
Maternal IgE is transferred to fetuses with IgG and minimally sensitizes fetal/neonatal skin mast cells	54
Corrigenda	54
Hemophagocytic lymphohistiocytosis–like hyperinflammation due to a de novo mutation in DPP9	53
Effect of age and season on respiratory mucosal immune marker profiles	53
Cis- and trans-eQTM analysis reveals novel epigenetic and transcriptomic immune markers of atopic asthma in airway epithelium	53
Cellular and systemic energy metabolic dysregulation in asthma development—a hypothesis-generating approach	53
Gene editing in allergic diseases: Identification of novel pathways and impact of deleting allergen genes	53
Clinical and humoral response after SARS-CoV-2 breakthrough infection in patients receiving immunosuppressant therapy	52
Perturbations of the T-cell receptor repertoire in response to SARS-CoV-2 in immunocompetent and immunocompromised individuals	52
Clinical and molecular correlates of the Index of Severity for Eosinophilic Esophagitis	52
Association between polymorphisms on chromosome 17q12-q21 and rhinovirus-induced interferon responses	52
Progress in understanding whether respiratory syncytial virus infection in infancy causes asthma in childhood	52
Hematopoietic cell transplantation for DOCK8 deficiency: Results from a prospective clinical trial	51
Trajectories and phenotypes of rhinitis and wheeze	51
Structural insights into MRGPRX2: A new vision of itch and allergy	51
Increased group 2 innate lymphoid cells in peripheral blood of adults with mastocytosis	50
Glycosylation enhances allergenic activity of major bee venom allergen Api m 1 by adding IgE epitopes	50
Central trained immunity and its impact on chronic inflammatory and autoimmune diseases	50
Diagnostic merits of the Eosinophilic Esophagitis Diagnostic Panel from a single esophageal biopsy	50
Target genes regulated by CLEC16A intronic region associated with common variable immunodeficiency	50
Utility of TH2 cell biomarkers to predict outcomes and treatment response in children with asthma	50
Defective STING expression potentiates IL-13 signaling in epithelial cells in eosinophilic chronic rhinosinusitis with nasal polyps	49
Caspase 8 sounds the alarm for allergic inflammation	49
Loss-of-phosphorylation of IKZF1 results in gain-of-function associated with immune dysregulation	49
The curious history behind a biologic-enriched cat food: Hyperimmune avian IgY as a means of oral adoptive passive immunization	49
Reply	49
Immune health grades: Finding resilience in the COVID-19 pandemic and beyond	48
Underrepresentation of Black and Hispanic trainees in allergy and immunology training and certification pipeline	47
The Editors’ Choice	47
The Editors’ Choice	47
Multiethnic genome-wide and HLA association study of total serum IgE level	47
News & Notes	47
The Editors’ Choice	46
Brief Overview of This Month's JACI	46
News Beyond Our Pages	46
CME Calendar-AAAAI	45
Information for Readers	45
Neutrophils: Knights in atopic armor	45
The Editors’ Choice	45
Editorial Board	45
Table of Contents	45
Asthma susceptibility: Learning from genetic diversity	44
News & Notes	44
Advances in chronic rhinosinusitis in 2020 and 2021	44
Editorial Board	44
Multilayer concept of autoimmune mechanisms and manifestations in inborn errors of immunity: Relevance for precision therapy	44
Reversal of SLE and hemophagocytic lymphohistiocytosis caused by lysinuric protein intolerance through allogeneic hematopoietic stem cell transplantation	44
Maternal exposures to acid suppressant medications or antibiotics and infant food allergy in a bronchiolitis cohort	44
The Editors’ Choice	44

Mentoring: A lifetime cycle and key to successful career development	44
Long-Term Follow-up after IMPACT Peanut Oral Immunotherapy Clinical Trial	43
Disrupted Foodways: Food Allergies and Food Insecurity	43
Real-world Treatment Outcomes of Lanadelumab in the Prevention of Hereditary Angioedema Attacks: an Interim Analysis of a Polish, Prospective, Multicenter, Observational Study (CHOPIN)	43
Innate immune cell dysregulation drives inflammation and disease in aspirin-exacerbated respiratory disease	43
Lipid mediators are detectable in the nasal epithelium and differ by asthma status in female subjects	43
Airway inflammation and dysbiosis in antibody deficiency despite the presence of IgG	42
Call to action: Air pollution, asthma, and allergy in the exposome era	42
Role of exosomes in allergic asthma: Signaling platforms between the epithelium and type 2 immunity	41
Reframing racial and ethnic disparities in atopic dermatitis in Black and Latinx populations	41
Emapalumab as bridge to hematopoietic cell transplant for STAT1 gain-of-function mutations	41
Deconvoluting the heterogeneity of SLE: The contribution of ancestry	41
News & Notes	41
Maternal nasal microbiota seed the offspring nasal microbiota in early infancy	41
Inequities in air pollution exposure and gaps in air quality monitoring	41
IPEX syndrome from diagnosis to cure, learning along the way	41
Patients with Pseudoallergic Reactions Following COVID-19 Vaccination are Able to Tolerate Subsequent Dosing	41
Cover 1	41
The efficacy and safety of systemic corticosteroids as first line treatment for granulomatous lymphocytic interstitial lung disease	41
Triggers for eosinophilic esophagitis (EoE): The intersection of food allergy and EoE	41
Allergen immunotherapy for atopic dermatitis: Systematic review and meta-analysis of benefits and harms	40
Hookworm infection: Toward development of safe and effective peptide vaccines	40
Respiratory and nonrespiratory symptoms before age 1 year predict school-age asthma	40
Lirentelimab for severe and chronic forms of allergic conjunctivitis	40
IL-4–STAT6 axis amplifies histamine-induced vascular endothelial dysfunction and hypovolemic shock	40
Advances and ongoing challenges in eosinophilic gastrointestinal disorders presented at the CEGIR/TIGERs Symposium at the 2024 American Academy of Allergy, Asthma & Immunology meeting	40
Table of Contents	39
IL-5 enhances human mast cell survival and interferon responses to viral infection	39
Table of Contents	39
Brief Overview of This Month's JACI	39
Information for Readers	39
CME Calendar-AAAAI	39
Information for Readers	38
Information for Readers	38
CME Calendar-AAAAI	38
Editorial Board	38
Continuing Medical Education Calendar	38
Identification of MOD000001, A Novel Highly Selective and Orally Available KIT Inhibitor Designed for Treatment of Mast Cell-Associated Disorders	38
Hypogammaglobulinemia and Risk of Infectious Complications in Patients Receiving Idecabtagene vicleucel	38
Brief Overview of This Month's JACI	38
Avapritinib Decreased Symptom Burden in Patients With Indolent Systemic Mastocytosis in the Registrational Double-Blind, Placebo-Controlled PIONEER Study	38
Table of Contents	38
Adherence of Child and Adolescent Patients Following Oral Immunotherapy to Peanuts	38
A powerful tool with a narrow focus: Aiming genome-wide association studies at chronic spontaneous urticaria	37
Booster doses of COVID-19 vaccine enhance neutralization efficiency against XBB.1.5	37
Do regional geography and race influence management of chronic spontaneous urticaria?	37
Mast Cell Degranulation Links Anti-PEG IgE to Anaphylaxis Caused by PEGylated Drugs and PEG-contained LNP/mRNA COVID Vaccines	37
News & Notes	37
Cover 1	37
Information for Readers	37
Cover 1	36
News beyond our pages	36
Cover 1	36
Efficacy Of Tezepelumab In Patients With Severe, Uncontrolled Asthma By Specific Perennial Allergen Immunoglobulin E Thresholds	36
Table of Contents	36
CME Calendar-AAAAI	36
Editorial Board	36
Reply	35
Exercise-induced laryngeal obstruction: A step in the right direction	35
The promise of sublingual and other immunotherapy options for infants and toddlers with food allergy	35
Brief Overview of This Month's JACI	35
Table of Contents	35
Trajectories of adiposity indicators and association with asthma and lung function in urban minority children	35
Lung function fluctuation patterns unveil asthma and COPD phenotypes unrelated to type 2 inflammation	35
Improving the reporting of allergic adverse events during immunotherapy for food allergy	35
A Special Thank-You to Our Reviewers	35
CME Calendar-AAAAI	35
Brief Overview of This Month's JACI	35
Elevated NK-cell transcriptional signature and dysbalance of resting and activated NK cells in atopic dermatitis	35
From the farm to the big city: Emerging health effects of agricultural emissions on asthma	35
Table of Contents	35
Cover 1	34
British Columbia, Canada, as a bellwether for climate-driven respiratory and allergic disorders	34
Table of Contents	34
Editorial Board	34
CME Calendar-AAAAI	34
Occupational health disparities: The pandemic as prism and prod	34
Moving forward with allergen immunotherapy: The significance of real-world studies	34
Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus	34
Patient-reported outcome measures for urticaria and angioedema	34
News Beyond Our Pages	34
Progressive Accumulation of Hyperinflammatory NKG2Dlow NK Cells in Early Life Defines a Novel Endotype of Severe Atopic Dermatitis	33
In silico exploration of atopic dermatitis phenotypes for clinical trial design optimization	33
Predictors of Increased Eosinophilic Esophagitis (EoE) Disease Activity After Proton Pump Inhibitor Therapy	33
Charlson Comorbidity Index and National Early Warning Score 2: Predictors of Mortality in COVID-19 Hospitalizations	33
Real-world Dupilumab Use in a Pediatric Allergy Clinic	33
Enhanced Cytokine Production in Children with Cutaneous Mastocytosis	33
Understanding Sesame Allergy in the Pediatric Population	33
Major Peanut Allergens Ara h 1, Ara h 2 and Ara h 8 Are Degraded and Fragmented Following High-Pressure and Temperature Autoclaving	33
Pediatric Asthma Post Hospitalization Phone Calls Increase Parental Self-Efficacy and Reduce 90 Day Emergency Department Visits	32
Clinical Characterization of Unresolved vs Resolved Chronic Cough Evaluated in a Primary Care Clinic	32
Variability of allergen quantity in commercially available peanut-containing foods	32
Characteristics of Patients with Food Allergy & Food Insecurity on a Prescription Supplemental Nutrition Program	32
Diagnostic Algorithms for Cashew Allergy in Children Reduce Oral Food Challenges and Overall Cost	32
Omalizumab Improves Outcomes In Patients With Nasal Polyps Regardless Of Their Asthma Status	31