Cell

Papers
(The median citation count of Cell is 26. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
ArticleCitations
Integrated analysis of multimodal single-cell data6192
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-193383
Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus3370
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals2803
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE22116
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues1794
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE21734
Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding1674
The Architecture of SARS-CoV-2 Transcriptome1665
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-191455
Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity1443
Adaptive immunity to SARS-CoV-2 and COVID-191336
The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity1306
SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract1213
Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology1146
Proteomic and Metabolomic Characterization of COVID-19 Patient Sera1100
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment1093
Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells1091
Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity1052
Hallmarks of aging: An expanding universe1028
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes915
Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera898
Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant874
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2841
SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies821
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications810
Mechanisms and disease consequences of nonalcoholic fatty liver disease804
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant804
The Global Phosphorylation Landscape of SARS-CoV-2 Infection798
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity781
Molecular Architecture of the SARS-CoV-2 Virus771
SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses754
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2730
The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic700
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers688
Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies686
The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19648
Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19641
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase638
Hallmarks of response, resistance, and toxicity to immune checkpoint blockade619
Multiple early factors anticipate post-acute COVID-19 sequelae604
Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy603
Case Study: Prolonged Infectious SARS-CoV-2 Shedding from an Asymptomatic Immunocompromised Individual with Cancer601
Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2597
Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin594
A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells588
SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron588
Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum578
COVID-19-neutralizing antibodies predict disease severity and survival561
Clinically Applicable AI System for Accurate Diagnosis, Quantitative Measurements, and Prognosis of COVID-19 Pneumonia Using Computed Tomography560
Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells560
The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas558
Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19557
Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum538
Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19537
Plant Immunity: Danger Perception and Signaling531
Pan-Genome of Wild and Cultivated Soybeans517
COVID-19 and the human innate immune system516
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein515
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity499
Gut-microbiota-targeted diets modulate human immune status496
Antibody evasion by the P.1 strain of SARS-CoV-2494
A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation490
Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2488
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition488
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer’s Disease486
COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas482
Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants478
A Thermostable mRNA Vaccine against COVID-19475
A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies473
Major Impacts of Widespread Structural Variation on Gene Expression and Crop Improvement in Tomato472
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS469
Effects of COVID-19 on the Nervous System468
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome468
A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice466
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays466
Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma462
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells454
A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA450
Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies446
A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2443
Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19441
Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front438
SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses437
Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera434
Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer431
β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway428
High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue427
Genome engineering for crop improvement and future agriculture425
Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2414
Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma407
Emerging Pandemic Diseases: How We Got to COVID-19406
Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)406
A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS404
Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19401
Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma390
Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes389
Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients387
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection384
Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant383
The Polygenic and Monogenic Basis of Blood Traits and Diseases382
Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment379
The basic immunology of asthma373
A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart370
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches368
Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations366
The Lymphatic Vasculature in the 21st Century: Novel Functional Roles in Homeostasis and Disease363
Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2363
Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing361
Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease360
Fibroblasts: Origins, definitions, and functions in health and disease359
Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution358
Antidepressant drugs act by directly binding to TRKB neurotrophin receptors357
Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection352
Enhanced prime editing systems by manipulating cellular determinants of editing outcomes351
A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer351
The Self-Organizing Genome: Principles of Genome Architecture and Function351
Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex350
Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity346
Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma345
Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage343
Atherosclerosis: Recent developments341
Massive expansion of human gut bacteriophage diversity336
Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity336
Molecular topography of an entire nervous system335
Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza333
The origins of SARS-CoV-2: A critical review332
The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis329
RNA-Mediated Feedback Control of Transcriptional Condensates328
A Genetic Map of the Response to DNA Damage in Human Cells326
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing321
The antigenic anatomy of SARS-CoV-2 receptor binding domain321
Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear320
Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron319
Bifidobacteria-mediated immune system imprinting early in life319
SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape318
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy315
The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling315
Circular RNAs: Characterization, cellular roles, and applications314
Genome-Scale Imaging of the 3D Organization and Transcriptional Activity of Chromatin314
Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer311
Functional characterization of the dural sinuses as a neuroimmune interface309
Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses304
Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection301
Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer301
Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells294
The Human and Mouse Enteric Nervous System at Single-Cell Resolution293
Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein292
Integrative Proteomic Characterization of Human Lung Adenocarcinoma291
Coast-to-Coast Spread of SARS-CoV-2 during the Early Epidemic in the United States291
A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model290
Integrated Morphoelectric and Transcriptomic Classification of Cortical GABAergic Cells289
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks289
Humoral and cellular immune memory to four COVID-19 vaccines286
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction286
High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios285
Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection284
Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity283
SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis281
Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy280
Endometriosis: Etiology, pathobiology, and therapeutic prospects279
Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor279
The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway278
Tackling COVID-19 with neutralizing monoclonal antibodies277
Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly274
Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema274
Spatially organized multicellular immune hubs in human colorectal cancer274
Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients273
Spatiotemporal analysis of human intestinal development at single-cell resolution273
Small RNAs are modified with N-glycans and displayed on the surface of living cells273
Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies272
Generation of Functional Human 3D Cortico-Motor Assembloids272
Adipose-tissue plasticity in health and disease270
Multi-organ proteomic landscape of COVID-19 autopsies270
The Rise of Molecular Glues265
Molecular Choreography of Acute Exercise264
Hallmarks of neurodegenerative diseases264
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes264
Ribosome Collisions Trigger General Stress Responses to Regulate Cell Fate263
Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy262
A route to de novo domestication of wild allotetraploid rice261
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression261
Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy261
Telomeres: history, health, and hallmarks of aging258
Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality257
Maturation and persistence of the anti-SARS-CoV-2 memory B cell response254
Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb254
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins254
The Tolman-Eichenbaum Machine: Unifying Space and Relational Memory through Generalization in the Hippocampal Formation251
Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination251
Co-option of Neutrophil Fates by Tissue Environments250
Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States248
Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine246
Hallmarks of Health246
Sleep Loss Can Cause Death through Accumulation of Reactive Oxygen Species in the Gut245
Pan-genome analysis of 33 genetically diverse rice accessions reveals hidden genomic variations243
Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike241
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients241
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output240
Proteogenomic characterization of pancreatic ductal adenocarcinoma239
A Quantitative Proteome Map of the Human Body238
Microscopic examination of spatial transcriptome using Seq-Scope237
Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation237
SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2235
Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment233
Identification of novel bat coronaviruses sheds light on the evolutionary origins of SARS-CoV-2 and related viruses232
Personalized Mapping of Drug Metabolism by the Human Gut Microbiome231
Cardioids reveal self-organizing principles of human cardiogenesis230
Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy223
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies222
Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system219
Genomic Epidemiology of SARS-CoV-2 in Guangdong Province, China219
Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution217
Circular RNA vaccines against SARS-CoV-2 and emerging variants216
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis214
Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans212
Bacterial Retrons Function In Anti-Phage Defense211
Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway211
A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance211
Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome208
Metabolic modeling of single Th17 cells reveals regulators of autoimmunity208
Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer207
Noninvasive Early Identification of Therapeutic Benefit from Immune Checkpoint Inhibition206
Nitric oxide signaling in health and disease206
Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species203
A single-cell atlas of chromatin accessibility in the human genome203
The Geometry of Abstraction in the Hippocampus and Prefrontal Cortex202
Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19199
Loss of epigenetic information as a cause of mammalian aging198
Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis197
Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration196
Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses196
An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells195
Mitocytosis, a migrasome-mediated mitochondrial quality-control process195
Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2194
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition191
Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos190
Maternal Fecal Microbiota Transplantation in Cesarean-Born Infants Rapidly Restores Normal Gut Microbial Development: A Proof-of-Concept Study190
Formation of NPR1 Condensates Promotes Cell Survival during the Plant Immune Response190
Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules190
Condensed Chromatin Behaves like a Solid on the Mesoscale In Vitro and in Living Cells190
RNA promotes the formation of spatial compartments in the nucleus189
An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies189
Spatially confined sub-tumor microenvironments in pancreatic cancer188
SnapShot: Ferroptosis188
CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment188
Hallmarks of environmental insults186
Massively parallel assessment of human variants with base editor screens185
T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals185
Cone-shaped HIV-1 capsids are transported through intact nuclear pores184
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