OOIR: Observatory of International Research

Papers

(The median citation count of Molecular Aspects of Medicine is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Editorial Board	258
Single-cell and spatial transcriptomics: Bridging current technologies with long-read sequencing	208
Delineating the contribution of ageing and physical activity to changes in mitochondrial characteristics across the lifespan	190
ILC in chronic inflammation, cancer and targeting with biologicals	153
Corticosteroid resistance in asthma: Cellular and molecular mechanisms	151
Extracellular vesicle interactions with the external and internal exposome in mediating carcinogenesis	149
Fibro-adipogenic progenitors in physiological adipogenesis and intermuscular adipose tissue remodeling	101
DNA melting analysis	98
The role of free fatty acid receptors activation in pancreatic disorders	96
Renal insufficiency and chronic kidney disease – Promotor or consequence of pathological post-translational modifications	92
Perspectives for the application of neurogenetic research in programming Neurorehabilitation	87
Data structuring may prevent ambiguity and improve personalized medical prognosis	78
Interactions between pathological and functional amyloid: A match made in Heaven or Hell?	74
CD33 isoforms in microglia and Alzheimer's disease: Friend and foe	70
Role of autophagy in muscle disease	64
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics	63
The thermodynamic hypothesis of protein aggregation	60
Bioactives and human health	57
Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis	57
Rodent genetically modified models of glaucoma	56
Antiviral therapeutics directed against RNA dependent RNA polymerases from positive-sense viruses	54
Autophagy signaling mediated by non-coding RNAs: Impact on breast cancer progression and treatment	46
Glucose-derived posttranslational modification in cardiovascular disease	43
Emerging technologies in personalized medicine	41
Editorial Board	41

Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies	41
Decoding driver and phenotypic genes in cancer: Unveiling the essence behind the phenomenon	40
Molecular mechanisms of oxidative stress in asthma	38
Strategies to deliver RNA by nanoparticles for therapeutic potential	36
Computational methods in glaucoma research: Current status and future outlook	36
Cellular and molecular mechanisms of allergic asthma	36
Kinetic mechanisms for O2 binding to myoglobins and hemoglobins	35
Invasive fungal infections: An expanding and evolving threat	35
RNA interference (RNAi)-based therapeutics for treatment of rare neurologic diseases	35
The recent blooming of therapeutic aptamers	34
An updated systematic review about various effects of microplastics on cancer: A pharmacological and in-silico based analysis	34
Editorial Board	33
Innate lymphoid cells (ILC) in SARS-CoV-2 infection	32
Circadian rhythms in the tissue-specificity from metabolism to immunity: insights from omics studies	31
Editorial Board	29
Molecular allergology approach to allergic asthma	29
Metabolic reprogramming shapes post-translational modification in macrophages	29
Role of hemoglobin structural-functional relationships in oxygen transport	28
NRF2-mediated regulation of lipid pathways in viral infection	28
Testicular immunity	28
Antifungal prophylaxis and pre-emptive therapy: When and how?	28
The enzymatic function of the honorary enzyme: S-nitrosylation of hemoglobin in physiology and medicine	28
Editorial Board	28
Irreversible post-translational modifications – Emerging cardiovascular risk factors	27
Diet and exercise in frailty and sarcopenia. Molecular aspects	27
Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms	26
Implications of obesity-mediated cellular dysfunction and adipocytokine signaling pathways in the pathogenesis of osteoarthritis	26
Extracellular vesicles as personalized medicine	26
From hemoglobin allostery to hemoglobin-based oxygen carriers	26
Systems to model the personalized aspects of microbiome health and gut dysbiosis	25
Frailty and biological age. Which best describes our aging and longevity?	25
Nicotinic receptors: From protein allostery to computational neuropharmacology	25
Association between glaucoma susceptibility with combined defects in mitochondrial oxidative phosphorylation and fatty acid beta oxidation	25
Hemoglobin allostery and pharmacology	25
Muscle aging and sarcopenia: The pathology, etiology, and most promising therapeutic targets	25
Inhibitory axes impacting on the activity and fate of Innate Lymphoid Cells	24
The folding and misfolding of multidomain proteins	24
Are we getting closer to a successful neoantigen cancer vaccine?	24
Caspase mechanisms in the regulation of inflammation	23
Pathological implication of protein post-translational modifications in cancer	23
NK cells and ILCs in tumor immunotherapy	23
Protein and RNA chaperones	23
The endogenous exposome of the pregnant mother: Placental extracellular vesicles and their effect on the maternal system	23
When to suspect and how properly early detect and treat patients with endemic mycoses	23
Autophagy in liver diseases: A review	23
Ubiquitin proteasome system and glaucoma: A survey of genetics and molecular biology studies supporting a link with pathogenic and therapeutic relevance	22
Phenotypic screening models for rapid diagnosis of genetic variants and discovery of personalized therapeutics	21
Molecular aspects of exposome and metabolic diseases	21
Virus-like particles of retroviral origin in protein aggregation and neurodegenerative diseases	21
Ellagitannins, urolithins, and neuroprotection: Human evidence and the possible link to the gut microbiota	21

Frustration in physiology and molecular medicine	21
Cardiovascular impact of emerging and Re-emerging Viruses: Pathophysiological mechanisms, diagnosis, and management with a pediatric focus	20
Cancer vaccines: Target antigens, vaccine platforms and preclinical models	20
Avenues for post-translational protein modification prevention and therapy	20
Modern methods of molecular diagnostics	20
Delivery of therapeutic agents and cells to pancreatic islets: Towards a new era in the treatment of diabetes	20
Adiponectin: its role in diabetic and pancreatic cancer	20
Non-canonical functions of autophagy proteins in immunity and infection	20
Hemoglobin: Multiple molecular interactions and multiple functions. An example of energy optimization and global molecular organization	19
Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects	19
Biochemical genesis of enzymatic and non-enzymatic post-translational modifications	19
Nanoformulations for dismantling fungal biofilms: The latest arsenals of antifungal therapy	18
Circulating tumor cells as liquid biopsy markers in cancer patients	18
NK cell surveillance of hematological malignancies. Therapeutic implications and regulation by chemokine receptors	17
Molecular targets and approaches to restore autophagy and lysosomal capacity in neurodegenerative disorders	17
Insights into Women's health: Exploring the vaginal microbiome, quorum sensing dynamics, and therapeutic potential of quorum sensing quenchers	17
Molecular aspects of optic nerve autophagy in glaucoma	17
Current and emerging sequencing-based tools for precision cancer medicine	17
Organ Fibrosis: Emerging diagnostic and therapeutic strategies	17
Editorial Board	17
Controlled release nanoplatforms for three commonly used chemotherapeutics	17
The functional role of the hemoglobin-water interface	17
Editorial-innate lymphoid cells, a new key component of the immune system	16
Diabetes and male fertility disorders	16
Vaccination against Helicobacter pylori – An approach for cancer prevention?	16
Emerging diagnostic and therapeutic challenges for skin fibrosis in systemic sclerosis	16
Health and nutrition beyond essential nutrients: The evolution of the bioactives concept for human health	15
Editorial Board	15
Hepatitis C virus chronicity and oncogenic potential: Vaccine development progress	15
Advances in understanding glaucoma pathogenesis: A multifaceted molecular approach for clinician scientists	14
Altitude acclimatization, hemoglobin-oxygen affinity, and circulatory oxygen transport in hypoxia	14
Pulmonary fibrosis: Emerging diagnostic and therapeutic strategies	14
Siglecs in health and disease	14
Diagnostic and therapeutic potential of protease inhibition	14
Editorial Board	14
Editorial Board	13
Genetic rodent models of glaucoma in representing disease phenotype and insights into the pathogenesis	13
The role of the microbiota in glaucoma	13
Molecular aspects of asthma	13
The bone-muscle unit: from mechanical coupling to soluble factors-mediated signaling	13
Frontiers in sarcopenia: Advancements in diagnostics, molecular mechanisms, and therapeutic strategies	12
Recent advances in intestinal fibrosis	12
Vaccines for breast cancer prevention: Are we there yet?	12
The uniqueness of on-demand male contraception	12
Impact of Siglecs on autoimmune diseases	12
Editorial Board	12
In vitro high-content tissue models to address precision medicine challenges	12
Beyond target cell death – Granzyme serine proteases in health and disease	12
Disentangling the nutrition-microbiota liaison in inflammatory bowel disease	11
Molecular determinants of peaceful coexistence versus invasiveness of non-Typhoidal Salmonella: Implications in long-term side-effects	10
Editorial Board	10
A pipeline for the development and analysis of extracellular vesicle-based transcriptomic biomarkers in molecular diagnostics	10
Editorial Board	10
Editorial Board	10
Editorial Board	10
Have safety and efficacy assessments of bioactives come of age?	10
Respiratory emerging viruses and drug resistance in lung cancer: challenges and new perspectives in treatment	9
Liver fibrosis in NAFLD/NASH: from pathophysiology towards diagnostic and therapeutic strategies	9
Signalling pathways and cell death mechanisms in glaucoma: Insights into the molecular pathophysiology	9
Therapeutic strategies for glaucoma and optic neuropathies	9
NK cell and ILC heterogeneity in colorectal cancer. New perspectives from high dimensional data	9
Editorial on proteases in health and disease	9
Revealing macropinocytosis using nanoparticles	9
Editorial Board	9