OOIR: Observatory of International Research

Papers

(The median citation count of Molecular Aspects of Medicine is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Vaccines for cancer prevention and treatment	230
Cancer vaccines: Target antigens, vaccine platforms and preclinical models	173
Metabolic reprogramming shapes post-translational modification in macrophages	172
Nuclear receptors: Key regulators of somatic cell functions in the ovulatory process	125
Nuclear receptors in the kidney during health and disease	118
Editorial Board	111
Extracellular vesicle interactions with the external and internal exposome in mediating carcinogenesis	88
Extracellular vesicles in the glioblastoma microenvironment: A diagnostic and therapeutic perspective	81
Introductory remarks	76
Modern methods of molecular diagnostics	72
Hemoglobin: Multiple molecular interactions and multiple functions. An example of energy optimization and global molecular organization	68
Biochemical genesis of enzymatic and non-enzymatic post-translational modifications	65
Editorial Board	62
Editorial Board	61
Editorial Board	56
Editorial Board	55
Editorial Board	54
Editorial Board	53
Molecular allergology approach to allergic asthma	53
Exploiting pilus-mediated bacteria-host interactions for health benefits	47
Revealing macropinocytosis using nanoparticles	46
ILC in chronic inflammation, cancer and targeting with biologicals	46
NK cell and ILC heterogeneity in colorectal cancer. New perspectives from high dimensional data	46
Galectins in allergic inflammatory diseases	45
Novel frontiers in neuroprotective therapies in glaucoma: Molecular and clinical aspects	40

Single-cell and spatial transcriptomics: Bridging current technologies with long-read sequencing	39
Therapeutic strategies for glaucoma and optic neuropathies	38
Circadian rhythms in the tissue-specificity from metabolism to immunity: insights from omics studies	35
Molecular determinants of peaceful coexistence versus invasiveness of non-Typhoidal Salmonella: Implications in long-term side-effects	35
Principles of digital sequencing using unique molecular identifiers	34
Microorganisms-derived antigens for preventive anti-cancer vaccines	34
Liver fibrosis in NAFLD/NASH: from pathophysiology towards diagnostic and therapeutic strategies	34
New perspectives on PPAR, VDR and FXRα as new actors in testicular pathophysiology	34
Nanoformulations for dismantling fungal biofilms: The latest arsenals of antifungal therapy	33
DNA melting analysis	33
Delineating the contribution of ageing and physical activity to changes in mitochondrial characteristics across the lifespan	33
Innate lymphoid cells (ILC) in SARS-CoV-2 infection	33
Circulating tumor cells as liquid biopsy markers in cancer patients	31
Neuroprotection in glaucoma: Mechanisms beyond intraocular pressure lowering	31
NRF2-mediated regulation of lipid pathways in viral infection	30
Fibro-adipogenic progenitors in physiological adipogenesis and intermuscular adipose tissue remodeling	30
Non-canonical functions of autophagy proteins in immunity and infection	30
Delivery of therapeutic agents and cells to pancreatic islets: Towards a new era in the treatment of diabetes	29
Antifungal prophylaxis and pre-emptive therapy: When and how?	29
Corticosteroid resistance in asthma: Cellular and molecular mechanisms	28
Diseases related to Notch glycosylation	28
A practical guide to spatial transcriptomics	27
Nuclear receptors, the aryl hydrocarbon receptor, and macrophage function	26
Polysialylation and disease	26
Recent advances, status, and opportunities of magneto-electric nanocarriers for biomedical applications	25
Controlled release nanoplatforms for three commonly used chemotherapeutics	25
Molecular aspects of optic nerve autophagy in glaucoma	24
Nuclear receptors in physiology and pathophysiology	24
Diabetes and male fertility disorders	24
Vaccination against Helicobacter pylori – An approach for cancer prevention?	24
Unveiling multifaceted roles of myeloid innate immune cells in the pathogenesis of psoriasis	24
Editorial Board	23
Data structuring may prevent ambiguity and improve personalized medical prognosis	23
Editorial on proteases in health and disease	23
Anatomical biology guides a search for nutrients for the aging brain	23
Still quoted after half a century	22
Editorial Board	22
Editorial Board	22
NK cell surveillance of hematological malignancies. Therapeutic implications and regulation by chemokine receptors	21
The functional role of the hemoglobin-water interface	21
Molecular targets and approaches to restore autophagy and lysosomal capacity in neurodegenerative disorders	21
Perspectives for the application of neurogenetic research in programming Neurorehabilitation	21
Organ Fibrosis: Emerging diagnostic and therapeutic strategies	21
Mechanistic insights into dietary (poly)phenols and vascular dysfunction-related diseases using multi-omics and integrative approaches: Machine learning as a next challenge in nutrition research	21
Impact of post-translational modification on the genesis and progression of diseases	20
Role of hemoglobin structural-functional relationships in oxygen transport	20
Diet and exercise in frailty and sarcopenia. Molecular aspects	20
Non-canonical roles of Siglecs: Beyond sialic acid-binding and immune cell modulation	20
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics	20
Insights into Women's health: Exploring the vaginal microbiome, quorum sensing dynamics, and therapeutic potential of quorum sensing quenchers	20

Protein synthesis in Mycobacterium tuberculosis as a potential target for therapeutic interventions	19
Cathepsin V: Molecular characteristics and significance in health and disease	19
Irreversible post-translational modifications – Emerging cardiovascular risk factors	19
Nuclear receptors, gestational metabolism and maternal metabolic disorders	19
Renal insufficiency and chronic kidney disease – Promotor or consequence of pathological post-translational modifications	19
Human colonic catabolism of dietary flavan-3-ol bioactives	19
Testicular immunity	18
Physiological and pathological aspects of epididymal sperm maturation	18
Dysregulation of host cell calcium signaling during viral infections: Emerging paradigm with high clinical relevance	18
Siglecs in allergy and asthma	18
Targeting O-GlcNAcylation to develop novel therapeutics	17
Neuronal autophagy and mitophagy in Parkinson's disease	17
Current and emerging sequencing-based tools for precision cancer medicine	17
PPARδ and its ligand erucic acid may act anti-tumoral, neuroprotective, and myelin protective in neuroblastoma, glioblastoma, and Parkinson's disease	16
Identification and characterization of post-translational modifications: Clinical implications	15
N-glycans as functional effectors of genetic and epigenetic disease risk	15
Role of autophagy in muscle disease	15
Kidney fibrosis: Emerging diagnostic and therapeutic strategies	15
The evolving regulatory landscape in regenerative medicine	15
Neuroglobin, clues to function and mechanism	15
Proteostasis in aging-associated ocular disease	15
The enzymatic function of the honorary enzyme: S-nitrosylation of hemoglobin in physiology and medicine	14
Exposome and foetoplacental vascular dysfunction in gestational diabetes mellitus	14
Emerging diagnostic and therapeutic challenges for skin fibrosis in systemic sclerosis	14
Signalling pathways and cell death mechanisms in glaucoma: Insights into the molecular pathophysiology	13
Extracellular vesicles as personalized medicine	13
(Poly)phenols and nitrolipids: Relevant participants in nitric oxide metabolism	13
CD33 isoforms in microglia and Alzheimer's disease: Friend and foe	13
Metabolomics in asthma: A platform for discovery	13
Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics	12
Thalassemias: from gene to therapy	12
The peroxidatic activities of Myoglobin and Hemoglobin, their pathological consequences and possible medical interventions	12
From hemoglobin allostery to hemoglobin-based oxygen carriers	12
Diagnostic and therapeutic potential of protease inhibition	12
Asthma COPD overlap: Insights into cellular and molecular mechanisms	12
Antiviral therapeutics directed against RNA dependent RNA polymerases from positive-sense viruses	12
Association between glaucoma susceptibility with combined defects in mitochondrial oxidative phosphorylation and fatty acid beta oxidation	11
Glucose-derived posttranslational modification in cardiovascular disease	11
Gene-environment interactions that influence CVD, lipid traits, obesity, diabetes, and hypertension appear to be able to influence gene therapy	11
Cancer-associated muscle weakness - From triggers to molecular mechanisms	11
Hepatitis C virus chronicity and oncogenic potential: Vaccine development progress	11
Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms	10
Drug delivery: Challenges and nanotechnology-based solutions	10
Hippo signaling modulation and its biological implications in urological malignancies	10
Editorial Board	10
Molecular and structural facets of c-di-GMP signalling associated with biofilm formation in Pseudomonas aeruginosa	10
Rodent genetically modified models of glaucoma	10
Functional consequences of lead and mercury exposomes in the heart	10
Understanding the complex genetics and molecular mechanisms underlying glaucoma	10
Editorial-innate lymphoid cells, a new key component of the immune system	9
Bioactives and human health	9
Health and nutrition beyond essential nutrients: The evolution of the bioactives concept for human health	9
Editorial Board	9
Introductory remarks	8
Muscle aging and sarcopenia: The pathology, etiology, and most promising therapeutic targets	8
Current understanding of genetics and epigenetics in pseudoexfoliation syndrome and glaucoma	8
Advances in understanding glaucoma pathogenesis: A multifaceted molecular approach for clinician scientists	8
Human sialoglycan ligands for immune inhibitory Siglecs	8
E3 ubiquitin ligase WWP2 as a promising therapeutic target for diverse human diseases	8
Editorial Board	8
Practical issues related to non-Aspergillus invasive mold infections	8
Frailty and biological age. Which best describes our aging and longevity?	8