OOIR: Observatory of International Research

Papers

(The TQCC of Molecular Aspects of Medicine is 25. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
The role of free fatty acid receptors activation in pancreatic disorders	279
Extracellular vesicle interactions with the external and internal exposome in mediating carcinogenesis	230
Fibro-adipogenic progenitors in physiological adipogenesis and intermuscular adipose tissue remodeling	173
DNA melting analysis	163
Corticosteroid resistance in asthma: Cellular and molecular mechanisms	163
Delineating the contribution of ageing and physical activity to changes in mitochondrial characteristics across the lifespan	118
Editorial Board	108
Single-cell and spatial transcriptomics: Bridging current technologies with long-read sequencing	102
CD33 isoforms in microglia and Alzheimer's disease: Friend and foe	100
Role of autophagy in muscle disease	90
Perspectives for the application of neurogenetic research in programming Neurorehabilitation	89
Data structuring may prevent ambiguity and improve personalized medical prognosis	84
Renal insufficiency and chronic kidney disease – Promotor or consequence of pathological post-translational modifications	77
Interactions between pathological and functional amyloid: A match made in Heaven or Hell?	72
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics	69
Autophagy signaling mediated by non-coding RNAs: Impact on breast cancer progression and treatment	64
Antiviral therapeutics directed against RNA dependent RNA polymerases from positive-sense viruses	62
Bioactives and human health	61
Rodent genetically modified models of glaucoma	60
Glucose-derived posttranslational modification in cardiovascular disease	58
Revisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis	55
The thermodynamic hypothesis of protein aggregation	45
Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies	44
Decoding driver and phenotypic genes in cancer: Unveiling the essence behind the phenomenon	42
Editorial Board	42

Emerging technologies in personalized medicine	41
Molecular mechanisms of oxidative stress in asthma	41
Invasive fungal infections: An expanding and evolving threat	40
Computational methods in glaucoma research: Current status and future outlook	39
Strategies to deliver RNA by nanoparticles for therapeutic potential	39
Cellular and molecular mechanisms of allergic asthma	39
An updated systematic review about various effects of microplastics on cancer: A pharmacological and in-silico based analysis	38
Kinetic mechanisms for O2 binding to myoglobins and hemoglobins	37
Mitophagy: A key regulator of radiotherapy resistance in the tumor immune microenvironment	37
RNA interference (RNAi)-based therapeutics for treatment of rare neurologic diseases	37
The recent blooming of therapeutic aptamers	36
Editorial Board	35
Editorial Board	34
Metabolic reprogramming shapes post-translational modification in macrophages	34
NRF2-mediated regulation of lipid pathways in viral infection	34
Antifungal prophylaxis and pre-emptive therapy: When and how?	33
Molecular allergology approach to allergic asthma	31
Editorial Board	31
The enzymatic function of the honorary enzyme: S-nitrosylation of hemoglobin in physiology and medicine	30
Testicular immunity	30
Molecular mechanism involved in sarcopenia and frailty, diagnosis and therapy	30
Diet and exercise in frailty and sarcopenia. Molecular aspects	30
Irreversible post-translational modifications – Emerging cardiovascular risk factors	29
Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms	29
Extracellular vesicles as personalized medicine	29
From hemoglobin allostery to hemoglobin-based oxygen carriers	29
Role of hemoglobin structural-functional relationships in oxygen transport	29
Muscle aging and sarcopenia: The pathology, etiology, and most promising therapeutic targets	28
Implications of obesity-mediated cellular dysfunction and adipocytokine signaling pathways in the pathogenesis of osteoarthritis	28
Frailty and biological age. Which best describes our aging and longevity?	28
Association between glaucoma susceptibility with combined defects in mitochondrial oxidative phosphorylation and fatty acid beta oxidation	28
Hemoglobin allostery and pharmacology	27
Systems to model the personalized aspects of microbiome health and gut dysbiosis	27
Nicotinic receptors: From protein allostery to computational neuropharmacology	27
Caspase mechanisms in the regulation of inflammation	26
The folding and misfolding of multidomain proteins	26
The endogenous exposome of the pregnant mother: Placental extracellular vesicles and their effect on the maternal system	26
Are we getting closer to a successful neoantigen cancer vaccine?	26
Protein and RNA chaperones	26
Autophagy in liver diseases: A review	25
When to suspect and how properly early detect and treat patients with endemic mycoses	25
Pathological implication of protein post-translational modifications in cancer	25
Virus-like particles of retroviral origin in protein aggregation and neurodegenerative diseases	25