OOIR: Observatory of International Research

Papers

(The TQCC of Brazilian Journal of Medical and Biological Research is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Isokinetic assessment of muscle function according to physical activity level and cardiovascular risk in asymptomatic adults aged 20 to 80 years	46
L-carnitine reduces acute lung injury via mitochondria modulation and inflammation control in pulmonary macrophages	17
Matteucinol combined with temozolomide inhibits glioblastoma proliferation, invasion, and progression: an in vitro, in silico, and in vivo study	16
Retraction notice for: “Suppressive effect of platycodin D on bladder cancer through microRNA-129-5p-mediated PABPC1/PI3K/AKT axis inactivation” [Braz J Med Biol Res 2021;54(3): e10222]	15
The LDL/HDL ratio predicts long-term risk of coronary revascularization in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: a cohort study	13
Beta-hydroxy-beta-methylbutyrate associated with low-intensity exercise training improves skeletal muscle regeneration through the IGF-Akt pathway	13
Patterns of renal and splanchnic sympathetic vasomotor activity in an animal model of survival to experimental sepsis	11
Effect of COVID-19 on cardiorenal axis: known or unknown universe?	11
Study of the relationship between regional cerebral saturation and pCO2 changes during mechanical ventilation to evaluate modifications in cerebral perfusion in a newborn piglet model	10
Clinical presentation and in-hospital prognosis of lung cancer patients presenting with suspected and confirmed COVID-19	10
Nephrotic syndrome in the elderly: epidemiological aspects, clinical data, and renal biopsy findings	10
Modeling functional network topology following stroke through graph theory: functional reorganization and motor recovery prediction	10
Kidney health for all: bridging the gap in kidney health education and literacy	9
Bidirectional genetic selection of behaviors involved in social interaction of Wistar rats	9
Down-regulation of autophagy proteins is associated with higher mTOR expression in the placenta of pregnant women with preeclampsia	9
Early introduction of exercise prevents insulin resistance in postnatal overfed rats	9
Nanosized copper particles induced mesangial cell toxicity via the autophagy pathway	9
Mild-to-moderate COVID-19 impact on the cardiorespiratory fitness in young and middle-aged populations	8
P2X7 receptor antagonist improves gastrointestinal disorders in spontaneously hypertensive rats	8
Exposure to air pollution and hospitalization due to COVID-19 in São José dos Campos, Brazil	8
Effects of the juçara fruit (Euterpe edulis Martius) pulp and lyophilized extract on NRF2, KEAP1, SOD1, and GPX2 expression in human colorectal cancer cell lines	7
Eight-year change in carotid intima-media thickness and associated risk factors in adults with and without psoriasis - the ELSA-Brasil cohort study	7
Anti-inflammatory, procollagen, and wound repair properties of topical insulin gel	7
Nephroprotective effect of exercise training in cisplatin-induced renal damage in mice: influence of training protocol	7
Cortical thickness is related to working memory performance after non-invasive brain stimulation	7

Bioinformatics-based design of a fusion vaccine with CTLA-4 variable region to combat Brucella	7
Telomerase inhibitors TMPyP4 and thymoquinone decreased cell proliferation and induced cell death in the non-small cell lung cancer cell line LC-HK2, modifying the pattern of focal adhesion	7
Extract of Cimicifuga racemosa (L.) Nutt protects ovarian follicle reserve of mice against in vitro deleterious effects of dexamethasone	6
Relaxation of thoracic aorta and pulmonary artery rings of marmosets (Callithrix spp.) by endothelium-derived 6-nitrodopamine	6
Influence of the addition of nanohydroxyapatite to scaffolds on proliferation and differentiation of human mesenchymal stem cells: a systematic review of in vitro studies	6
Is domestic polyester suitable for plastination of thin brain slices?	6
Effect of silibinin and trans-chalcone in an Alzheimer's disease-like model generated by insulin amyloids	6
Unlocking the molecular realm: advanced approaches for identifying clinically and environmentally relevant bacteria	6
High prevalence of HPV 18 and multiple infections with oncogenic HPV genotypes in women at risk of cervical cancer examined in Manaus, Brazil	6
Dietary phytate induces subclinical mechanical allodynia in mice	6
Predictors of mortality in critically ill patients with COVID-19 and diabetes	5
Identification of carboxymethyl (CM)-binding proteins derived from Lolium multiflorum pollen extract and antibody reactivity in Brazilian allergic patients	5
FRZB: a potential prognostic marker for head and neck squamous cell carcinoma	5
The level of Tim-3+CD8+ T cells can serve as a potential marker for evaluating the severity of acute graft-versus-host disease after haplo-PBSCT	5
Leptin and interleukin-1β levels associated with osteoarthritis in Vietnamese patients: a cross-sectional analysis	5
Sialic acid as the potential link between lipid metabolism and inflammation in the pathogenesis of atherosclerosis	5
A semi-automated microscopic image analysis method for scoring Ki-67 nuclear immunostaining	5
Influence of reminiscence therapy on mental health and quality of life in elderly patients with unresectable, metastatic gastrointestinal cancer	5
Safety of a 90-min duration of intravenous infusion of obinutuzumab in patients with B-cell non-Hodgkin's lymphoma in a tertiary hospital in China: a prospective, open-label, exploratory clinical tria	5
Potential biomarkers as a predictive factor of response to primary chemotherapy in breast cancer patients	4
ACE gene polymorphisms (rs4340) II and DI are more responsive to the ergogenic effect of caffeine than DD on aerobic power, heart rate, and perceived exertion in a homogeneous Brazilian group of adole	4
Periodontitis and osteoporosis: a two-sample Mendelian randomization analysis	4
Poricoic acid A attenuates renal fibrosis by inhibiting endoplasmic reticulum stress-mediated apoptosis	4
Bioinformatic features and immunological response of recombinant antigen CTLA4-IgV-EgG1Y162 against Echinococcus granulosus	4
Low-intensity pulsed ultrasound inhibits chondrocyte senescence by inhibiting PI3K/AKT/mTOR signaling	4
SNORA5A regulates tumor-associated macrophage M1/M2 phenotypes via TRAF3IP3 in breast cancer	4
Factors associated with cystic fibrosis mortality before the age of 30: retrospective analysis of a cohort in southern Brazil	4
Esculetin attenuates cerebral ischemia-reperfusion injury and protects neurons through Nrf2 activation in rats	4
Prevalence of invasive yeast infections in a COVID-19 intensive care unit in northeastern Brazil	4
Dynactin knockdown leads to synuclein aggregation by blocking autophagy in a zebrafish model of Parkinson's disease	4
Cognitive behavioral stress management effectively facilitates neurologic recovery, alleviates mental distress, and elevates health status in acute ischemic stroke patients	4
FNDC5/Irisin in dementia and cognitive impairment: update and novel perspective	4
Exercise: a non-drug strategy of NK cell activation	4
Saccharomyces boulardii supplementation does not affect anaerobic power gain induced by short-term sprint interval training in physically active individuals	4
Cellular and molecular mechanisms of Notch signal in pulmonary microvascular endothelial cells after acute lung injury	3
Investigations on the cytotoxicity and antimicrobial activities of terezine E and 14-hydroxyterezine D	3
Poor prognosis indicators of type-2 diabetic COVID-19 patients	3
Is the variation in monocyte to high-density lipoprotein cholesterol ratio a predictor of major cardiovascular events after acute coronary syndrome?	3
Benzodiazepine partially reverses tonic-clonic seizures induced by thiocolchicoside	3
The protective role of raltegravir in experimental acute lung injury in vitro and in vivo	3
The combination of berberine and evodiamine ameliorates high-fat diet-induced non-alcoholic fatty liver disease associated with modulation of gut microbiota in rats	3
MiR-501-3p/SPC24 axis affects cell proliferation, migration, invasion, apoptosis, and prognosis in renal cell carcinoma	3
Is there a higher frequency of anal dysplasia and infection by human papillomavirus in Crohn's disease patients?	3
Inspiratory muscle training as adjuvant therapy in obstructive sleep apnea: a randomized controlled trial	3
Factors affecting executive function performance of Brazilian elderly in the Stroop test	3
Concomitant TP53 mutation in early-stage resected EGFR-mutated non-small cell lung cancer: a narrative approach in a genetically admixed Brazilian cohort	3
Reference equations of oxygen uptake for the step test in the obese population	3
Erratum notice for: “Unlocking the molecular realm: advanced approaches for identifying clinically and environmentally relevant bacteria” [Braz J Med Biol Res 2023: 56, e12894]	3
N-glycosylation of ACTRIIB enhances protein stability leading to rapid cell proliferation and strong resistance to docetaxel in nasopharyngeal carcinoma	3
Lactate modulates cardiac gene expression in mice during acute physical exercise	3

Different acquisition systems for heart rate variability analysis may lead to diverse outcomes	3
Post-discharge mortality in adult patients hospitalized for tuberculosis: a prospective cohort study	3
Rectal roflumilast improves trinitrobenzenesulfonic acid-induced chronic colitis in rats	3
A short review on the features of the non-obese diabetic Goto-Kakizaki rat intestine	2
Ovarian hormones influence immune response to liver ischemia-reperfusion	2
MicroRNA-181a regulates Treg functions via TGF-β1/Smad axis in the spleen of mice with acute gouty arthritis induced by MSU crystals	2
Didymin protects against polystyrene nanoplastic-induced hepatic damage in male albino rats by modulation of Nrf-2/Keap-1 pathway	2
Association among cardiopulmonary and metabolic rehabilitation, arrhythmias, and myocardial ischemia responses of patients with HFpEF or HFmrEF	2
Correlation of acoustic voice analysis and Voice Handicap Index in patients with postoperative unilateral vocal cord paralysis after thyroid surgery	2
Retraction notice for: Notoginsenoside R1 upregulates miR-221-3p expression to alleviate ox-LDL-induced apoptosis, inflammation, and oxidative stress by inhibiting the TLR4/NF-κB pathway in HUVECs	2
Nutrition management by a multidisciplinary team for prevention of nutritional deficits and morbidity following esophagectomy	2
Serum autophagy-related gene 5 level in stroke patients: correlation with CD4+ T cells and cognition impairment during a 3-year follow-up	2
Diagnostic and prognostic value of the gasdermins in gastric cancer	2
The role of the PKCζ/JNK signaling pathway in regulating the development of femoral head necrosis	2
The duration-dependent and sex-specific effects of neonatal sevoflurane exposure on cognitive function in rats	2
Resveratrol as a cardioprotective adjuvant for 5-fluorouracil in the treatment of gastric cancer cells	2
Characterization of the normal fetal circulatory system of the ductus venosus using sound complexity parameters	2
Silencing ANGPT2 alleviates ulcerative colitis by regulating autophagy-mediated NLRP3 inflammasome inactivation via the mTOR signaling pathway	2
Evaluating the dissemination of evolutionary biology concepts in medicine	2
The role and mechanisms of cordycepin in inhibiting cancer cells	2
Astragaloside IV alleviates lung inflammation in Klebsiella pneumonia rats by suppressing TGF-β1/Smad pathway	2
Immuno-oncology in head and neck squamous cell carcinoma - a narrative review	2
Cardiorespiratory fitness as a mediator in the relationship between lung function and blood pressure in adults	2
Association of coronary artery calcium with heart rate variability in the Brazilian Longitudinal Study of Adult Health - ELSA-Brasil	2
Foxa1 mediates eccrine sweat gland development through transcriptional regulation of Na-K-ATPase expression	2
Botulinum toxin improved intestinal adaptation to short gut in a twenty-one-day-old weanling rat	2
Natural product Eriocalyxin B exerts anti-tumor effects by downregulating TCEA3 expression and sensitizes immune checkpoint blockade therapy in osteosarcoma	2
1α,25-Dihydroxyvitamin D3 accelerates skin wound re-epithelialization by promoting epidermal stem cell proliferation and differentiation through PI3K activation: an in vitro and in vivo study	2
Diabetes, hemoglobin A1c, and cognitive performance in older adults: is there any impact of frailty? Evidence from the ELSI-Brazil study	2
Synergistic effect of venetoclax and ibrutinib on ibrutinib-resistant ABC-type DLBCL cells	2
Effects of N-butanol extract of Amygdalus mongolica on rats with bleomycin‐induced pulmonary fibrosis based on metabolomics	2
Selective inhibition of interleukin 6 receptor decreased inflammatory cytokines and increased proteases in an experimental model of critical calvarial defect	2
Coptisine ameliorates colitis in mice by modulating cPLA2/TRPM8/CGRP-1 signaling pathways and strengthening intestinal barrier function	2
Assessing multiple factors affecting the gut microbiome structure of very preterm infants	2
The inhibitor of the redox activity of APE1/REF-1, APX2009, reduces the malignant phenotype of breast cancer cells	2
Association between Expanded Disability Status Scale score and dietary antioxidant capacity in patients with multiple sclerosis	2
The myocardial capillary network is altered in congenital diaphragmatic hernia in the fetal rabbit model	2
Barriers to patient recruitment in a poststroke neurorehabilitation multicenter trial in Brazil	2
In vitro effects of lapachol and β-lapachone against Leishmania amazonensis	2
A model for preservation of thymocyte-depleted thymus	2
ABCG2 polymorphism and rivaroxaban pharmacokinetics in healthy individuals after a single dose	2
Clenbuterol and metformin ameliorate cachexia parameters, but only clenbuterol reduces tumor growth via lipid peroxidation in Walker 256 tumor-bearing rats	2
Strenuous swimming raises blood non-enzymatic antioxidant capacity in rats	2
Rac1 overexpression promotes Treg-derived cytokines to mediate choroidal neovascularization in wet age-related macular degeneration	2
Phospholipase D regulates ferroptosis signal transduction in mouse spleen hypoxia response	2
Chemoprotective effect of arbutin on azoxymethane-induced aberrant crypt foci in rat colon via modulation of PCNA/Bax protein	2
Is near-infrared spectroscopy a promising predictor for early intracranial hemorrhage diagnosis in the Emergency Department?	2
GSK3B inhibition reduced cervical cancer cell proliferation and migration by modulating the PI3K/Akt signaling pathway and epithelial-to-mesenchymal transition	2
Therapeutic effects of whole-body vibration on postmenopausal women with osteoporosis: a systematic review and meta-analysis	2
Effect of MCH1, a fatty-acid amide hydrolase inhibitor, on the depressive-like behavior and gene expression of endocannabinoid and dopaminergic-signaling system in the mouse nucleus accumbens	2
Erratum notice for: “Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways” [Braz J Med Biol Res 2020;53(2): e8793]	2