OOIR: Observatory of International Research

Papers

(The TQCC of Immunological Reviews is 22. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Issue Information	285
Cover Image	149
Contribution of animal models to the mechanistic understanding of Alternative Pathway and Amplification Loop (AP/AL)‐driven Complement‐mediated Diseases	142
In Defense of Homeostasis: Innate Immunity in Cardiac Injury and Repair	138
Metabolic regulation of type I interferon production	136
Reframing Thymic Biology: From AIRE to Mimetics, Thymflammation, Regeneration, and Beyond	135
The Structural Biology of T‐Cell Antigen Detection at Close Contacts	122
Superoxide: The enigmatic chemical chameleon in neutrophil biology	122
The Thymus Regeneration Paradox: The Search for Stemness in an Involuting Organ	121
Intrathymic Regulation of Dendritic Cell Subsets and Their Contributions to Central Tolerance	103
Bridging pDCs and cDCs : The Identity of Transitional Dendritic Cells	100
NETosis: Sculpting tumor metastasis and immunotherapy	98
Cytotoxicity as a form of immunogenic cell death leading to efficient tumor antigen cross‐priming	91
Role of inflammasomes and neuroinflammation in epilepsy	88
Antigen‐specific and cross‐reactive T cells in protection and disease	85
Immune checkpoint inhibitors in infectious disease	84
Human autoantibodies neutralizing type I IFNs: From 1981 to 2023	82
IgE‐Mediated Activation of Mast Cells and Basophils in Health and Disease	79
Issue Information	78
The trajectory of human B‐cell function, immune deficiency, and allergy revealed by inborn errors of immunity	71
Layered origins of lymphoid tissue inducer cells	69
Mechanisms Promoting Stability of B Cells	65
Allosteric Changes Underlie the Outside‐In Transmission of Activatory Signals in the TCR	64
Inflammasome Activation by RNA Respiratory Viruses: Mechanisms, Viral Manipulation, and Therapeutic Insights	64
Clearance phagocytosis by the retinal pigment epithelial during photoreceptor outer segment renewal: Molecular mechanisms and relation to retinal inflammation	62

Stimuli‐responsive nanodelivery systems for amplifying immunogenic cell death in cancer immunotherapy	61
With complements: C3 inhibition in the clinic	61
The immune system in Down Syndrome: Autoimmunity and severe infections	61
B‐1 lymphocytes in adipose tissue as innate modulators of inflammation linked to cardiometabolic disease	59
The importance of IgG glycosylation—What did we learn after analyzing over 100,000 individuals	59
Inflammasome‐mediated pyroptosis in defense against pathogenic bacteria	58
Cover Image	56
Issue Information	56
Functional Insights From Immunoreceptor Structures	55
Targeted therapy for non‐small‐cell lung cancer: New insights into regulated cell death combined with immunotherapy	53
An introduction to neuroimmunology	52
Sex Differences in Lung Immunity	52
	51
Transcriptional Regulation of Mouse Mast Cell Differentiation and the Role of Human Lung Mast Cells in Airway Inflammation	51
	51
Issue Information	51
Artery Tertiary Lymphoid Organs Form Neuroimmune Cardiovascular Interfaces in Atherosclerosis	50
Sex Differences in Asthma Pathogenesis	50
Autoimmunity and the microbiome	50
Common variable immunodeficiency, cross currents, and prevailing winds	50
Cortical Thymic Epithelial Cells: Key Developers of the Code of T‐Cell Selection and TCR Repertoire Diversity	49
Immune Mechanisms of Viral, Autoimmune, and Immune Checkpoint Inhibitor‐Associated Myocarditis	49
T1‐T2 Interplay in the Complex Immune Landscape of Severe Asthma	49
Correction to “The Journey Toward Disease Modification in Cow Milk Protein Allergy”	48
Dendritic Cell Organization and Function in Innate and Adaptive Immune Defense Within Lymph Nodes	48
Maternal influences on offspring food allergy	48
Targeting Bottlenecks in Malaria Transmission: Antibody‐Epitope Descriptions Guide the Design of Next‐Generation Biomedical Interventions	47
Gene regulation in inborn errors of immunity: Implications for gene therapy design and efficacy	47
Axes of heterogeneity in human tissue‐resident memory T cells	46
Deconstructing the Thymic Microenvironment Through Genesis to Senescence	45
Fc‐FcγR interactions during infections: From neutralizing antibodies to antibody‐dependent enhancement	45
Glycobiology of IgE	42
Defensive‐lipid droplets: Cellular organelles designed for antimicrobial immunity	42
JAK/STAT defects and immune dysregulation, and guiding therapeutic choices	41
Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity	41
MAP Kinase Signaling at the Crossroads of Inflammasome Activation	40
PANoptosis: Mechanisms, biology, and role in disease	40
GC B Cells, Tfh Cells, and Influenza bnAbs : Insights for Improving Universal Vaccine Design	38
Targeting Inflammation in Atherosclerotic Cardiovascular Disease: Mechanisms and Emerging Therapies	38
Human neutrophils ≠ murine neutrophils: Does it matter?	38
Modulation of immunity by the secreted phospholipase A₂ family	38
	37
	37
Cover Image	37
Factor D	36
Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis	36
Structural studies offer a framework for understanding the role of properdin in the alternative pathway and beyond	35
Ketone body metabolism and the NLRP3 inflammasome in Alzheimer's disease	35
Structural Immunology of SARS‐CoV‐2	35
Anti‐Modified Protein Antibodies in Rheumatoid Arthritis: Pathogenic, Protective, or Passive Bystander?	35

From Lymphotoxin to Tertiary Lymphoid Structures and Beyond	33
Rethinking Immunity in Tissues: The Biology of Tertiary Lymphoid Structures	32
Integrative Roles of Pro‐Inflammatory Cytokines on Airway Smooth Muscle Structure and Function in Asthma	32
Gut microbiota as a sensor of autoimmune response and treatment for rheumatoid arthritis	31
Fc gamma receptors: Their evolution, genomic architecture, genetic variation, and impact on human disease	31
	31
Understanding inhibitory receptor function in neutrophils through the lens of CLEC12A	31
Development and organization of omental milky spots	31
Cell type‐specific molecular mechanisms and implications of necroptosis in inflammatory respiratory diseases	31
Protein therapeutics and their lessons: Expect the unexpected when inhibiting the multi‐protein cascade of the complement system	31
The X Factor in Immunity: Sex Differences Shaped by the X Chromosome	30
Counteracting Influenza Virus Evolution Through the Full Spectrum of Broadly Protective Antibodies	30
Irritable bowel syndrome: When food is a pain in the gut	30
Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design	30
Cover Image	29
Cover Image	29
Biology of IgE	29
Deciphering visceral adipose tissue regulatory T cells: Key contributors to metabolic health	29
Innate Immunity and Asthma Exacerbations: Insights From Human Models	28
Low‐molecular weight inhibitors of the alternative complement pathway	28
Metabolic adaptations determine whether natural killer cells fail or thrive within the tumor microenvironment	28
Hemophagocytic lymphohistiocytosis: A disorder of T cell activation, immune regulation, and distinctive immunopathology	28
Type 2 IgG Memory B Cells and Long‐Lived IgE Plasma Cells in the Persistence of Allergy	28
Metabolic Stress and Immune Activation in Heart Failure With a Preserved Ejection Fraction	28
Neutrophils in aging and aging‐related pathologies	27
Epigenomic regulation of macrophage polarization: Where do the nuclear receptors belong?	27
Can fecal microbiota transplantations modulate autoimmune responses in type 1 diabetes?	27
No time to die: Epigenetic regulation of natural killer cell survival	27
Alternative pathway activation in pregnancy, a measured amount “complements” a successful pregnancy, too much results in adverse events	27
Issue Information	26
Swimming Through Dendritic Cell Biology: Insights From Fish Models	26
Issue Information	26
	26
The impact of the human gut microbiome on the treatment of autoimmune disease	26
Human Atypical B Cells. An Overview	26
The impact of neuroinflammation on neuronal integrity	26
Contributions of animal models to mechanistic understandings of antibody‐dependent disease and roles of the amplification loop	26
	25
ILC2 Diversity, Location, and Function in Pulmonary Disease	25
Myocardial Immune Niches in Homeostasis and Inflammation	25
	25
Ontogenetic Diversification of Type 2 Conventional Dendritic Cells in the Bone Marrow: A Central Logic for Peripheral Immunity	25
Microbes and the fate of neutrophils	24
Issue Information	24
Sex Differences in Metabolite–Immune Circuits of Neuroinflammation	24
Innate Immune Sensors in Health and Disease	24
Dendritic Cell Heterogeneity Tailored to Their Function	24
Signals that control MAIT cell function in healthy and inflamed human tissues	24
Inflammation‐Driven Lymphoid Structures: Organization, Function, and Clinical Impact Across Autoimmunity, Cancer, and Checkpoint Toxicity	24
Thymflammation: The Role of a Constitutively Active Inflammatory Network and “Ectopic” Cell Types in the Thymus in the Induction of T Cell Tolerance and Beyond	24
Innate Immune Receptors as Dynamic Modulators of Extrafollicular Autoimmune B Cell Response	23
Understanding the diversity and dynamics of in vivo efferocytosis: Insights from the fly embryo	23
G protein coupled pattern recognition receptors expressed in neutrophils: Recognition, activation/modulation, signaling and receptor regulated functions	23
Thymic Dendritic Cells Revisited	22
The evolving landscape of immune‐related adverse events that follow immune checkpoint immunotherapy in cancer patients	22