OOIR: Observatory of International Research

Papers

(The TQCC of Immunological Reviews is 21. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Issue Information	306
Bridging pDCs and cDCs : The Identity of Transitional Dendritic Cells	258
The Thymus Regeneration Paradox: The Search for Stemness in an Involuting Organ	235
Cover Image	133
NETosis: Sculpting tumor metastasis and immunotherapy	124
Cytotoxicity as a form of immunogenic cell death leading to efficient tumor antigen cross‐priming	121
Metabolic regulation of type I interferon production	120
The Structural Biology of T‐Cell Antigen Detection at Close Contacts	118
Reframing Thymic Biology: From AIRE to Mimetics, Thymflammation, Regeneration, and Beyond	105
Superoxide: The enigmatic chemical chameleon in neutrophil biology	103
Role of inflammasomes and neuroinflammation in epilepsy	101
Antigen‐specific and cross‐reactive T cells in protection and disease	92
Intrathymic Regulation of Dendritic Cell Subsets and Their Contributions to Central Tolerance	91
Immune checkpoint inhibitors in infectious disease	81
Contribution of animal models to the mechanistic understanding of Alternative Pathway and Amplification Loop (AP/AL)‐driven Complement‐mediated Diseases	77
In Defense of Homeostasis: Innate Immunity in Cardiac Injury and Repair	76
Human autoantibodies neutralizing type I IFNs: From 1981 to 2023	72
Issue Information	71
IgE‐Mediated Activation of Mast Cells and Basophils in Health and Disease	71
The trajectory of human B‐cell function, immune deficiency, and allergy revealed by inborn errors of immunity	69
Thymic and extrathymic Aire‐expressing cells in maternal‐fetal tolerance*	67
Mechanisms Promoting Stability of B Cells	63
Inflammasome Activation by RNA Respiratory Viruses: Mechanisms, Viral Manipulation, and Therapeutic Insights	60
Allosteric Changes Underlie the Outside‐In Transmission of Activatory Signals in the TCR	59
Inflammasome‐mediated pyroptosis in defense against pathogenic bacteria	58

Layered origins of lymphoid tissue inducer cells	58
Clearance phagocytosis by the retinal pigment epithelial during photoreceptor outer segment renewal: Molecular mechanisms and relation to retinal inflammation	55
The immune system in Down Syndrome: Autoimmunity and severe infections	55
Stimuli‐responsive nanodelivery systems for amplifying immunogenic cell death in cancer immunotherapy	55
B‐1 lymphocytes in adipose tissue as innate modulators of inflammation linked to cardiometabolic disease	54
With complements: C3 inhibition in the clinic	54
Autoimmunity and the microbiome	51
Maternal influences on offspring food allergy	51
The importance of IgG glycosylation—What did we learn after analyzing over 100,000 individuals	51
Issue Information	50
Cover Image	50
	49
Functional Insights From Immunoreceptor Structures	49
	48
Sex Differences in Lung Immunity	48
Sex Differences in Asthma Pathogenesis	48
Immune Mechanisms of Viral, Autoimmune, and Immune Checkpoint Inhibitor‐Associated Myocarditis	46
T1‐T2 Interplay in the Complex Immune Landscape of Severe Asthma	46
Issue Information	46
An introduction to neuroimmunology	45
Dendritic Cell Organization and Function in Innate and Adaptive Immune Defense Within Lymph Nodes	45
Artery Tertiary Lymphoid Organs Form Neuroimmune Cardiovascular Interfaces in Atherosclerosis	45
Transcriptional Regulation of Mouse Mast Cell Differentiation and the Role of Human Lung Mast Cells in Airway Inflammation	45
Cortical Thymic Epithelial Cells: Key Developers of the Code of T‐Cell Selection and TCR Repertoire Diversity	44
Common variable immunodeficiency, cross currents, and prevailing winds	43
Targeted therapy for non‐small‐cell lung cancer: New insights into regulated cell death combined with immunotherapy	43
JAK/STAT defects and immune dysregulation, and guiding therapeutic choices	42
Targeting Bottlenecks in Malaria Transmission: Antibody‐Epitope Descriptions Guide the Design of Next‐Generation Biomedical Interventions	42
Glycobiology of IgE	42
Correction to “The Journey Toward Disease Modification in Cow Milk Protein Allergy”	42
Issue Information	42
Fc‐FcγR interactions during infections: From neutralizing antibodies to antibody‐dependent enhancement	41
Gene regulation in inborn errors of immunity: Implications for gene therapy design and efficacy	41
Deconstructing the Thymic Microenvironment Through Genesis to Senescence	40
Axes of heterogeneity in human tissue‐resident memory T cells	40
Defensive‐lipid droplets: Cellular organelles designed for antimicrobial immunity	39
Modulation of immunity by the secreted phospholipase A₂ family	39
	38
PANoptosis: Mechanisms, biology, and role in disease	38
Human neutrophils ≠ murine neutrophils: Does it matter?	38
Cover Image	38
MAP Kinase Signaling at the Crossroads of Inflammasome Activation	38
Structural studies offer a framework for understanding the role of properdin in the alternative pathway and beyond	37
Factor D	37
Ketone body metabolism and the NLRP3 inflammasome in Alzheimer's disease	36
Structural Immunology of SARS‐CoV‐2	36
Integrative Roles of Pro‐Inflammatory Cytokines on Airway Smooth Muscle Structure and Function in Asthma	36
From Lymphotoxin to Tertiary Lymphoid Structures and Beyond	36
Fc gamma receptors: Their evolution, genomic architecture, genetic variation, and impact on human disease	35
Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis	35

	35
	35
Irritable bowel syndrome: When food is a pain in the gut	33
Cell type‐specific molecular mechanisms and implications of necroptosis in inflammatory respiratory diseases	32
Host immune responses in the central nervous system during fungal infections	32
The X Factor in Immunity: Sex Differences Shaped by the X Chromosome	31
Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design	31
Deciphering visceral adipose tissue regulatory T cells: Key contributors to metabolic health	30
Development and organization of omental milky spots	30
Understanding inhibitory receptor function in neutrophils through the lens of CLEC12A	30
Gut microbiota as a sensor of autoimmune response and treatment for rheumatoid arthritis	29
Cover Image	28
Issue Information	28
Cover Image	28
Protein therapeutics and their lessons: Expect the unexpected when inhibiting the multi‐protein cascade of the complement system	28
Low‐molecular weight inhibitors of the alternative complement pathway	27
Can fecal microbiota transplantations modulate autoimmune responses in type 1 diabetes?	27
Tissue immunity to SARS‐CoV‐2: Role in protection and immunopathology*	27
Metabolic Stress and Immune Activation in Heart Failure With a Preserved Ejection Fraction	26
Epigenomic regulation of macrophage polarization: Where do the nuclear receptors belong?	26
Human Atypical B Cells. An Overview	26
Immunogenicity and efficacy of Ad26.COV2.S: An adenoviral vector–based COVID‐19 vaccine	26
Type 2 IgG Memory B Cells and Long‐Lived IgE Plasma Cells in the Persistence of Allergy	26
Neutrophils in aging and aging‐related pathologies	26
Alternative pathway activation in pregnancy, a measured amount “complements” a successful pregnancy, too much results in adverse events	26
Biology of IgE	26
No time to die: Epigenetic regulation of natural killer cell survival	26
Metabolic adaptations determine whether natural killer cells fail or thrive within the tumor microenvironment	26
Innate Immunity and Asthma Exacerbations: Insights From Human Models	26
Hemophagocytic lymphohistiocytosis: A disorder of T cell activation, immune regulation, and distinctive immunopathology	25
Issue Information	25
The nervous system during COVID‐19: Caught in the crossfire	24
The impact of the human gut microbiome on the treatment of autoimmune disease	24
Contributions of animal models to mechanistic understandings of antibody‐dependent disease and roles of the amplification loop	24
Issue Information	24
ILC2 Diversity, Location, and Function in Pulmonary Disease	24
Ontogenetic Diversification of Type 2 Conventional Dendritic Cells in the Bone Marrow: A Central Logic for Peripheral Immunity	24
	24
The impact of neuroinflammation on neuronal integrity	24
Swimming Through Dendritic Cell Biology: Insights From Fish Models	24
Issue Information	23
	23
Understanding the diversity and dynamics of in vivo efferocytosis: Insights from the fly embryo	23
Established and emerging roles for mitochondria in neutrophils	23
	23
Signals that control MAIT cell function in healthy and inflamed human tissues	22
The evolving landscape of immune‐related adverse events that follow immune checkpoint immunotherapy in cancer patients	22
Microbes and the fate of neutrophils	22
Gastrointestinal mucosal toxicities from immune checkpoint inhibitors: Current understanding and future directions	22
Sex Differences in Metabolite–Immune Circuits of Neuroinflammation	22
Thymflammation: The Role of a Constitutively Active Inflammatory Network and “Ectopic” Cell Types in the Thymus in the Induction of T Cell Tolerance and Beyond	21
G protein coupled pattern recognition receptors expressed in neutrophils: Recognition, activation/modulation, signaling and receptor regulated functions	21
Innate Immune Receptors as Dynamic Modulators of Extrafollicular Autoimmune B Cell Response	21
Dendritic Cell Heterogeneity Tailored to Their Function	21
	21
Thymic Dendritic Cells Revisited	21
Innate Immune Sensors in Health and Disease	21
A comprehensive review of sensors of radiation‐induced damage, radiation‐induced proximal events, and cell death	21