OOIR: Observatory of International Research

Papers

(The TQCC of Biotechnology Letters is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Surfactants: physicochemical interactions with biological macromolecules	75
Biogenically proficient synthesis and characterization of silver nanoparticles employing marine procured fungi Aspergillus brunneoviolaceus along with their antibacterial and antioxidative potency	62
The synergy between LPMOs and cellulases in enzymatic saccharification of cellulose is both enzyme- and substrate-dependent	61
Circular RNA circ_0032821 contributes to oxaliplatin (OXA) resistance of gastric cancer cells by regulating SOX9 via miR-515-5p	43
Comparative evaluation of silver nanoparticles biosynthesis by two cold-tolerant Streptomyces strains and their biological activities	40
Superoxide dismutase as multipotent therapeutic antioxidant enzyme: Role in human diseases	37
Potential of antimicrobial topical gel with synthesized biogenic silver nanoparticle using Rhodomyrtus tomentosa leaf extract and silk sericin	34
The effect of exosomes derived from mesenchymal stem cells in the treatment of induced type 1 diabetes mellitus in rats	34
Enzymatic potential for the valorization of agro-industrial by-products	32
Biosynthesis of magnetic iron oxide nanoparticles: a review	32
Engineered formate dehydrogenase from Chaetomium thermophilum, a promising enzymatic solution for biotechnical CO2 fixation	29
Soil amendment in plastic greenhouse using modified biochar: soil bacterial diversity responses and microbial biomass carbon and nitrogen	28
Co-delivery of miRNA-15a and miRNA-16–1 using cationic PEGylated niosomes downregulates Bcl-2 and induces apoptosis in prostate cancer cells	26
A review of CRISPR associated genome engineering: application, advances and future prospects of genome targeting tool for crop improvement	26
Neuroprotection of melatonin on spinal cord injury by activating autophagy and inhibiting apoptosis via SIRT1/AMPK signaling pathway	24
MicroRNA miR-212 regulates PDCD4 to attenuate Aβ25–35-induced neurotoxicity via PI3K/AKT signaling pathway in Alzheimer’s disease	24
Piperine inhibits colorectal cancer migration and invasion by regulating STAT3/Snail-mediated epithelial–mesenchymal transition	23
Microbial fuel cell biosensor for the determination of biochemical oxygen demand of wastewater samples containing readily and slowly biodegradable organics	22
Kinetic characterization of purified laccase from Trametes hirsuta: a study on laccase catalyzed biotransformation of 1,4-dioxane	22
Design and development of a new ambr250® bioreactor vessel for improved cell and gene therapy applications	22
Enhancement of fatty acid biosynthesis by exogenous acetyl-CoA carboxylase and pantothenate kinase in Escherichia coli	21
Inhibition of berberine hydrochloride on Candida albicans biofilm formation	21
Low-quality animal by-product streams for the production of PHA-biopolymers: fats, fat/protein-emulsions and materials with high ash content as low-cost feedstocks	21
Bacillus subtilis CtpxS2-1 induces systemic resistance against anthracnose in Andean lupin by lipopeptide production	20
Effect of a novel postbiotic containing lactic acid bacteria on the intestinal microbiota and disease resistance of rainbow trout (Oncorhynchus mykiss)	20

Kinetic models of biological hydrogen production by Enterobacter aerogenes	20
Marine bacterial community analysis on 316L stainless steel coupons by Illumina MiSeq sequencing	20
Algal and cyanobacterial biomass as potential dye biodecolorizing material: a review	19
Current trends in biopharmaceuticals production in Escherichia coli	19
Autophagy induced by Schwann cell-derived exosomes promotes recovery after spinal cord injury in rats	19
LncRNA TUG1 promotes esophageal cancer development through regulating PLK1 expression by sponging miR-1294	19
Circ_0114876 promoted IL-1β-induced chondrocyte injury by targeting miR-671/TRAF2 axis	19
CRISPR/Cas9-mediated genome editing in Penicillium oxalicum and Trichoderma reesei using 5S rRNA promoter-driven guide RNAs	18
Alginate oligosaccharide protects endothelial cells against oxidative stress injury via integrin-α/FAK/PI3K signaling	17
Terpenoid indole alkaloid biosynthesis in Catharanthus roseus: effects and prospects of environmental factors in metabolic engineering	17
Biological synthesis of nicotinamide mononucleotide	16
Cyanidin-3-glucoside prevents hydrogen peroxide (H2O2)-induced oxidative damage in HepG2 cells	16
Enhanced production of Aspergillus niger inulinase from sugar beet molasses and its kinetic modeling	16
Biosensors for penicillin quantification: a comprehensive review	15
Temperature-controlled molecular weight of hyaluronic acid produced by engineered Bacillus subtilis	15
Homology modeling and heterologous expression of highly alkaline subtilisin-like serine protease from Bacillus halodurans C-125	15
Biochemical characterization of extracellular fructosyltransferase from Aspergillus oryzae IPT-301 immobilized on silica gel for the production of fructooligosaccharides	15
Transcriptome expression profiles reveal response mechanisms to drought and drought-stress mitigation mechanisms by exogenous glycine betaine in maize	15
Food-grade expression of nattokinase in Lactobacillus delbrueckii subsp. bulgaricus and its thrombolytic activity in vitro	15
Response surface statistical optimization of fermentation parameters for resveratrol production by the endophytic fungus Arcopilus aureus and its tyrosinase inhibitory activity	14
The disruption of the MAPKK gene triggering the synthesis of flavonoids in endophytic fungus Phomopsis liquidambaris	14
Biosynthetic process and strain improvement approaches for industrial penicillin production	14
MicroRNA-127-3p regulates myoblast proliferation by targeting Sept7	14
Valorization of sugar beet pulp through biotechnological approaches: recent developments	14
Plant-derived VLP: a worthy platform to produce vaccine against SARS-CoV-2	14
Optimization of activated charcoal detoxification and concentration of chestnut shell hydrolysate for xylitol production	14
Identification of the PP2C gene family in paper mulberry (Broussonetia papyrifera) and its roles in the regulation mechanism of the response to cold stress	14
Multiple gene integration to promote erythritol production on glycerol in Yarrowia lipolytica	13
Functional characterization of wheat myo-inositol oxygenase promoter under different abiotic stress conditions in Arabidopsis thaliana	13
One-step purification and immobilization of recombinant proteins using SpyTag/SpyCatcher chemistry	13
Improved AP-3 production through combined ARTP mutagenesis, fermentation optimization, and subsequent genome shuffling	13
Bacterial type VI secretion system (T6SS): an evolved molecular weapon with diverse functionality	13
Circ_0001247 functions as a miR-1270 sponge to accelerate cervical cancer progression by up-regulating ZEB2 expression level	13
Antifungal action of chitosan in combination with fungicides in vitro and chitosan conjugate with gallic acid on tomatoes against Botrytis cinerea	13
Evolution and expression analysis of CDPK genes under drought stress in two varieties of potato	12
A plant-based transient expression system for the rapid production of highly immunogenic Hepatitis E virus-like particles	12
Larvicidal activity against Aedes aegypti and molecular docking studies of compounds extracted from the endophytic fungus Aspergillus sp. isolated from Bertholletia excelsa Humn. & Bonpl	12
Overexpression of circ_0001445 decelerates hepatocellular carcinoma progression by regulating miR-942-5p/ALX4 axis	12
Mechanical loading induces HIF-1α expression in chondrocytes via YAP	12
Mycelial culture extracts of selected wood-decay mushrooms as a source of skin-protecting factors	12
Three-dimensional tissue fabrication system by co-culture of microalgae and animal cells for production of thicker and healthy cultured food	12
Engineering the regulatory site of the catalase promoter for improved heterologous protein production in Pichia pastoris	11
Effect of agitation speed and aeration rate on fructosyltransferase production of Aspergillus oryzae IPT-301 in stirred tank bioreactor	11
Evaluation of hepatic drug-metabolism for glioblastoma using liver-brain chip	11
In silico design and in vitro expression of novel multiepitope DNA constructs based on HIV-1 proteins and Hsp70 T-cell epitopes	11
Purification and characterization of glucoamylase of Aspergillus oryzae from Luzhou-flavour Daqu	11
Umbelliferone esters with antibacterial activity produced by lipase-mediated biocatalytic pathway	11
RETRACTED ARTICLE: Characterization of a new bacteriocin-like inhibitory peptide produced by Lactobacillus sakei B-RKM 0559	11
MiR-103/miR-107 inhibits enterovirus 71 replication and facilitates type I interferon response by regulating SOCS3/STAT3 pathway	11
Combination of atmospheric and room temperature plasma (ARTP) mutagenesis, genome shuffling and dimethyl sulfoxide (DMSO) feeding to improve FK506 production in Streptomyces tsukubaensis	11

Simultaneous saccharification and lactic acid fermentation of the cellulosic fraction of municipal solid waste using Bacillus smithii	11
Antifungal effects of lycorine on Botrytis cinerea and possible mechanisms	11
The immune response to a recombinant Lactococcus lactis oral vaccine against foot-and-mouth disease virus in mice	11
Establishment and optimization of a high-throughput mimic perfusion model in ambr® 15	11
Bluemomycin, a new naphthoquinone derivative from Streptomyces sp. with antimicrobial and cytotoxic properties	11
Improvement of tacrolimus production in Streptomyces tsukubaensis by mutagenesis and optimization of fermentation medium using Plackett–Burman design combined with response surface methodology	11
Influence of organic solvents in the extraction and purification of torularhodin from Sporobolomyces ruberrimus	10
Enhancement of glucaric acid production in Saccharomyces cerevisiae by expressing Vitreoscilla hemoglobin	10
ATP dynamic regeneration strategy for enhancing co-production of glutathione and S-adenosylmethionine in Escherichia coli	10
Detection of homologous recombination events in SARS-CoV-2	10
Annotation of AMP-activated protein kinase genes and its comparative transcriptional analysis between high and low lipid producing strains of Mucor circinelloides	10
Proteomic analysis reveals the damaging role of low redox laccase from Yersinia enterocolitica strain 8081 in the midgut of Helicoverpa armigera	10
Tea polyphenols-loaded nanocarriers: preparation technology and biological function	10
miR-375-3p contributes to hypoxia-induced apoptosis by targeting forkhead box P1 (FOXP1) and Bcl2 like protein 2 (Bcl2l2) in rat cardiomyocyte h9c2 cells	10
3D reconstruction and morphological analysis of electrostimulated hyperthermophile biofilms of Thermotoga neapolitana	10
Functional variations between Mesenchymal Stem Cells of different tissue origins: A comparative gene expression profiling	10
Biochemical characterization of a surfactant-stable keratinase purified from Proteus vulgaris EMB-14 grown on low-cost feather meal	10
Nitrate modulation of Bacillus sp. biofilm components: a proposed model for sustainable bioremediation	9
Characterization and comparative genomic analysis of gamma-aminobutyric acid (GABA)-producing lactic acid bacteria from Thai fermented foods	9
Systematically gap-filling the genome-scale metabolic model of CHO cells	9
Characterization and engineering of two new GH9 and GH48 cellulases from a Bacillus pumilus isolated from Lake Bogoria	9
Preparation, purification, and characterization of low-molecular-weight hyaluronic acid	9
LC-MS/MS-based quantitative proteomic and phosphoproteomic analysis of CHO-K1 cells adapted to growth in glutamine-free media	9
Production of sesquiterpene patchoulol in mitochondrion-engineered Saccharomyces cerevisiae	9
Application of RecET-Cre/loxP system in Corynebacterium glutamicum ATCC14067 for l-leucine production	9
Inhibition of Salmonella enteritidis biofilms by Salmonella invasion protein-targeting aptamer	9
Characterization and inhibition of four fungi producing citrinin in various culture media	9
Recombinant expression of sericin-cecropin fusion protein and its functional activity	9
Augmenting the expression of accD and rbcL genes using optimized iron concentration to achieve higher biomass and biodiesel in Chlorella vulgaris	9
Investigation of the gut microbiome of Apis cerana honeybees from Vietnam	9
Bufalin inhibits the malignant development of non-small cell lung cancer by mediating the circ_0046264/miR-522-3p axis	9
The indigoidine synthetase BpsA provides a colorimetric ATP assay that can be adapted to quantify the substrate preferences of other NRPS enzymes	9
Obtaining hemicellulosic hydrolysate from sugarcane bagasse for microbial oil production by Lipomyces starkeyi	9
Bone marrow mesenchymal stem cell-derived exosomes loaded with miR-26a through the novel immunomodulatory peptide DP7-C can promote osteogenesis	9
Lipopeptide production by Bacillus atrophaeus strain B44 and its biocontrol efficacy against cotton rhizoctoniosis	9
Characterization of a recombinant sucrose isomerase and its application to enzymatic production of isomaltulose	9
Aerobic biodegradation of high explosive hexahydro-1,3,5- trinitro-1,3,5-triazine by Janibacter cremeus isolated from contaminated soil	9
Soybean peptides promote yoghurt fermentation and quality	9
In vivo delivery of a multiepitope peptide and Nef protein using novel cell-penetrating peptides for development of HIV-1 vaccine candidate	9
Influence of 16S rRNA reference databases in amplicon-based environmental microbiome research	8
Synthesis of (R)-mandelic acid and (R)-mandelic acid amide by recombinant E. coli strains expressing a (R)-specific oxynitrilase and an arylacetonitrilase	8
Promoter engineering for high ectoine production in a lower saline medium by Halomonas hydrothermalis Y2	8
Food-grade γ-aminobutyric acid production by immobilized glutamate decarboxylase from Lactobacillus plantarum in rice vinegar and monosodium glutamate system	8
Carbohydrate analysis of Mortierella alpina by colorimetry and HPLC–ELSD to reveal accumulation differences of sugar and lipid	8
De novo biosynthesis of 2′-fucosyllactose in engineered Pichia pastoris	8
Characterization of a thermostable and solvent-tolerant laccase produced by Streptomyces sp. LAO	8
A recycled batch biotransformation strategy for 22-hydroxy-23,24-bisnorchol-4-ene-3-one production from high concentration of phytosterols by mycobacterial resting cells	8
Surface charge engineering of Thermomyces lanuginosus lipase improves enzymatic activity and biodiesel synthesis	8
Enhancement of cordycepin production from Cordyceps militaris culture by epigenetic modification	8
Effect of Ag-1031 on apoptosis in gastric cancer AGS cells and its effects on the PI3K/AKT/mTOR signaling pathway	8
Functional and structural evaluation of the antileukaemic enzyme l-asparaginase II expressed at low temperature by different Escherichia coli strains	8
Production of 1,3-propanediol and lactic acid from crude glycerol by a microbial consortium from intertidal sludge	8
By targeting TRAF6, miR-140-3p inhibits TGF-β1-induced human osteosarcoma epithelial-to-mesenchymal transition, migration, and invasion	8
Optimization for allitol production from d-glucose by using immobilized glucose isomerase and recombinant E. coli expressing d-psicose-3-epimerase, ribitol dehydrogenase and formate dehydrogenase	8
Continuous production of fructooligosaccharides by recycling of the thermal-stable β-fructofuranosidase produced by Aspergillus niger	7
Efficient CRISPR/Cas9-mediated gene editing in Guangdong small-ear spotted pig cells using an optimized electrotransfection method	7
Knock out of sHSP genes determines some modifications in the probiotic attitude of Lactiplantibacillus plantarum	7
Keratinases from Coriolopsis byrsina as an alternative for feather degradation: applications for cloth cleaning based on commercial detergent compatibility and for the production of collagen hydrolysa	7
Purification and characterization of a native lytic polysaccharide monooxygenase from Thermoascus aurantiacus	7
Enhanced β-carotene production by overexpressing the DID2 gene, a subunit of ESCRT complex, in engineered Yarrowia lipolytica	7
Stem cells or their exosomes: which is preferred in COVID-19 treatment?	7
Identification of key pathways and differentially expressed genes in bronchopulmonary dysplasia using bioinformatics analysis	7
Enhancement of protoplast preparation and regeneration of Hirsutella sinensis based on process optimization	7
Enrichment and detection of circulating tumor cells by immunomagnetic beads and flow cytometry	7
Recombinant ferritin nanoparticles can induce dendritic cell maturation through TLR4/NF-κB pathway	7
The carbon partitioning of glucose and DIC in mixotrophic, heterotrophic and photoautotrophic cultures of Tetraselmis suecica	7
Co-evolution of β-glucosidase activity and product tolerance for increasing cellulosic ethanol yield	7
Characterization of Lactobacillus reuteri WQ-Y1 with the ciprofloxacin degradation ability	7
Evaluation of hypoglycemic therapeutics and nutritional supplementation for type 2 diabetes mellitus management: An insight on molecular approaches	7
Eustigmatophyte strains with potential interest in cancer prevention and treatment: partial chemical characterization and evaluation of cytotoxic and antioxidant activity	7
Small design from big alignment: engineering proteins with multiple sequence alignment as the starting point	7
Archaeal and bacterial community structures of rural household biogas digesters with different raw materials in Qinghai Plateau	7
Synthesis of novel nicotinamide susbstituted phthalocyanine and photodynamic antomicrobial chemotherapy evaluation potentiated by potassium iodide against the gram positive S. aureus and gram negative	7
Uncoupling glucose sensing from GAL metabolism for heterologous lactose fermentation in Saccharomyces cerevisiae	7