OOIR: Observatory of International Research

Papers

(The H4-Index of Biomaterials is 86. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Editorial Board	758
Editorial Board	380
Breast implant silicone exposure induces immunogenic response and autoimmune markers in human periprosthetic tissue	321
Engineering supramolecular dynamics of self-assembly and turnover of oncogenic microRNAs to drive their synergistic destruction in tumor models	315
Antigen self-presenting dendrosomes swallowing nanovaccines boost antigens and STING agonists codelivery for cancer immunotherapy	260
Systemically administered platelet-inspired nanoparticles to reduce inflammation surrounding intracortical microelectrodes	233
Potentiating the effect of immunotherapy in pancreatic cancer using gas-entrapping materials	231
Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain	209
Pulmonary myeloid cell uptake of biodegradable nanoparticles conjugated with an anti-fibrotic agent provides a novel strategy for treating chronic allergic airways disease	192
Development of human pluripotent stem cell-derived hepatic organoids as an alternative model for drug safety assessment	189
A NIR-II emissive sonosensitized biotuner for pyroptosis-enhanced sonodynamic therapy of hypoxic tumors	181
Antibiotics armed neutrophils as a potential therapy for brain fungal infection caused by chemotherapy-induced neutropenia	177
Multifaceted cancer alleviation by cowpea mosaic virus in a bioprinted ovarian cancer peritoneal spheroid model	176
Early phago-/endosomal escape of platinum drugs via ROS-responsive micelles for dual cancer chemo/immunotherapy	168
Tumor stromal topography promotes chemoresistance in migrating breast cancer cell clusters	161
Self-reinforced photodynamic immunostimulator to downregulate and block PD-L1 for metastatic breast cancer treatment	160
Orchestrated metal-coordinated carrier-free celastrol hydrogel intensifies T cell activation and regulates response to immune checkpoint blockade for synergistic chemo-immunotherapy	154
Two-dimensional nanomaterials-added dynamism in 3D printing and bioprinting of biomedical platforms: Unique opportunities and challenges	146
The use of heparin/polycation coacervate sustain release system to compare the bone regenerative potentials of 5 BMPs using a critical sized calvarial bone defect model	142
Inhalable DNase I@Au hybrid nanoparticles for radiation sensitization and metastasis inhibition by elimination of neutrophil extracellular traps	141
A neoteric antibacterial ceria-silver nanozyme for abiotic surfaces	141
Mammary tissue-derived extracellular matrix hydrogels reveal the role of irradiation in driving a pro-tumor and immunosuppressive microenvironment	138
X-ray-activated nanoscintillators integrated with tumor-associated neutrophils polarization for improved radiotherapy in metastatic colorectal cancer	137
Calcium phosphate-based biomaterials trigger human macrophages to release extracellular traps	136
Murine macrophages or their secretome delivered in alginate dressings enhance impaired wound healing in diabetic mice	133

Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine	133
Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia	132
“On/off”-switchable crosslinked PTX-nanoformulation with improved precise delivery for NSCLC brain metastases and restrained adverse reaction over nab-PTX	131
Exosomes from hypoxic urine-derived stem cells facilitate healing of diabetic wound by targeting SERPINE1 through miR-486-5p	128
Versatile conductive hydrogel orchestrating neuro–immune microenvironment for rapid diabetic wound healing through peripheral nerve regeneration	127
Exosome-decorated bio-heterojunctions reduce heat and ROS transfer distance for boosted antibacterial and tumor therapy	127
Rapamycin-encapsulated costimulatory ICOS/CD40L-bispecific nanoparticles restrict pathogenic helper T-B-cell interactions while in situ suppressing mTOR for lupus treatment	127
LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy	126
Enzymatic non-covalent synthesis of supramolecular assemblies as a general platform for bioorthogonal prodrugs activation to combat drug resistance	125
Intraoperative application of intelligent, responsive, self-assembling hydrogel rectifies oxygen and energy metabolism in traumatically injured brain	123
Fusogenic liposomes encapsulating mitochondria as a promising delivery system for osteoarthritis therapy	123
Biomimetic nanostructural materials based on placental amniotic membrane-derived nanofibers for self-healing and anti-adhesion during cesarean section	121
Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation	121
Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage	121
Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and osteogenesis	119
Locally delivered modified citrus pectin - a galectin-3 inhibitor shows expected anti-inflammatory and unexpected regeneration-promoting effects on repair of articular cartilage defect	116
Uncloaking cell-impermeant gold nanorods via tumor microenvironmental cathepsin B facilitates cancer cell penetration and potent radiosensitization	110
Regenerative capacity of neural tissue scales with changes in tissue mechanics post injury	108
Mitochondria-targeting materials and therapies for regenerative engineering	108
Both non-coated and polyelectrolytically-coated intraocular collagen-alginate composite gels enhanced photoreceptor survival in retinal degeneration	108
Gradient conducting polymer surfaces with netrin-1-conjugation promote axon guidance and neuron transmission of human iPSC-derived retinal ganglion cells	108
Biomaterial based implants caused remote liver fatty deposition through activated blood-derived macrophages	108
Editorial Board	107
Suspension culture of human induced pluripotent stem cell-derived intestinal organoids using natural polysaccharides	106
Folate conjugated nanomedicines for selective inhibition of mTOR signaling in polycystic kidneys at clinically relevant doses	106
Cryogel vaccines effectively induce immune responses independent of proximity to the draining lymph nodes	106
Calcium phosphate nanoclusters modify periodontium remodeling and minimize orthodontic relapse	105
Effect of carbon nanomaterial dimension on the functional activity and degeneration of neurons	105
A supramolecular polymer-collagen microparticle slurry for bone regeneration with minimal growth factor	105
Corrigendum to ‘Bioprinting 3D microfibrous scaffolds for engineering cardiac tissues and heart-on-a-chip’ [Biomaterials Volume 110, (2016) Pages 45–59]	104
AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery	102
Bifunctional black phosphorus quantum dots platform: Delivery and remarkable immunotherapy enhancement of STING agonist	100
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis	99
Patch grafting of organoids of stem/progenitors into solid organs can correct genetic-based disease states	98
Galacto-oligosaccharides as an anti-bacterial and anti-invasive agent in lung infections	98
Shape memory micro-anchors with magnetic guidance for precision micro-vascular deployment	98
Heteroantigen-assembled nanovaccine enhances the polyfunctionality of TILs against tumor growth and metastasis	96
Cr(V)–Cr(III) in-situ transition promotes ROS generation to achieve efficient cancer therapy	96
Insensitivity of dental pulp stem cells migration to substrate stiffness	96
Editorial Board	96
Retraction notice to “Phototherapy together with it triggered immunological response for Anti-HPV treatment of oropharyngeal cancer: Removing tumor and pathogenic virus simultaneously” [Biomaterials (	96
Editorial Board	96
Injectable bioresponsive bone adhesive hydrogels inhibit NLRP3 inflammasome on demand to accelerate diabetic fracture healing	95
Tailoring photobiomodulation to enhance tissue regeneration	93
Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood	93
Evaluation of immobilized microspheres of Clonostachys rosea on Botrytis cinerea and tomato seedlings	93
Ink-jet 3D printing as a strategy for developing bespoke non-eluting biofilm resistant medical devices	93
Nanoparticles targeting OPN loaded with BY1 inhibits vascular restenosis by inducing FTH1-dependent ferroptosis in vascular smooth muscle cells	93
Engineering a 3D collective cancer invasion model with control over collagen fiber alignment	92
Nano-enabled photosynthesis in tumours to activate lipid peroxidation for overcoming cancer resistances	92

A low-energy emulsification platform based on a Diet Coke–Mentos reaction-derived bubbly flow for formulating various emulsions as drug carriers	91
Omentum-on-a-chip: A multicellular, vascularized microfluidic model of the human peritoneum for the study of ovarian cancer metastases	91
Graphene oxide-functionalized nanocomposites promote osteogenesis of human mesenchymal stem cells via enhancement of BMP-SMAD1/5 signaling pathway	91
Polymeric nanoparticle gel for intracellular mRNA delivery and immunological reprogramming of tumors	89
Glutaminolysis inhibition boosts photodynamic therapy to eliminate cancer stem cells	88
Activation of the cGAS-STING pathway combined with CRISPR-Cas9 gene editing triggering long-term immunotherapy	88
Rationally integrating peptide-induced targeting and multimodal therapies in a dual-shell theranostic platform for orthotopic metastatic spinal tumors	88
“One-stitch” bioorthogonal prodrug activation based on cross-linked lipoic acid nanocapsules	88
Biomaterials for reliable wearable health monitoring: Applications in skin and eye integration	88
Intravital imaging and single cell transcriptomic analysis for engraftment of mesenchymal stem cells in an animal model of interstitial cystitis/bladder pain syndrome	87
Polyprodrug nanomedicine for chemiexcitation-triggered self-augmented cancer chemotherapy and gas therapy	87
Injectable and photocurable CAR-T cell formulation enhances the anti-tumor activity to melanoma in mice	86
Inhalable pH-responsive DNA tetrahedron nanoplatform for boosting anti-tumor immune responses against metastatic lung cancer	86
Self-preparation system using glucose oxidase-inspired nitroreductase amplification for cascade-responsive drug release and multidrug resistance reversion	86