OOIR: Observatory of International Research

Papers

(The H4-Index of Biomaterials is 85. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Corrigendum to ‘Engineered cell-laden human protein-based elastomer’ [34 (2013), 5496–5505]	688
Design and development of novel self-assembled catechol-modified bile acid conjugates as pH-responsive apical sodium-dependent bile acid transporter targeting nanoparticles	346
A functional 3D full-thickness model for comprehending the interaction between airway epithelium and connective tissue in cystic fibrosis	300
Retraction notice to “Viability and proliferation of rat MSCs on adhesion protein-modified PET and PU scaffolds” [Biomaterials 33/12 (2012) 8094–8103]	294
Restoring mammary gland structures and functions with autogenous cell therapy	237
Nanoassembly of doxorubicin-conjugated polyphosphoester and siRNA simultaneously elicited macrophage- and T cell- mediated anticancer immune response for cancer therapy	218
Acoustic-holography-patterned primary hepatocytes possess liver functions	210
Dynamic injectable tissue adhesives with strong adhesion and rapid self-healing for regeneration of large muscle injury	204
Recombinant programmed cell death protein 1 functions as an immune check point blockade and enhances anti-cancer immunity	187
Bioorthogonal chemistry and illumination controlled programmed size-changeable nanomedicine for synergistic photodynamic and hypoxia-activated therapy	183
Pulmonary myeloid cell uptake of biodegradable nanoparticles conjugated with an anti-fibrotic agent provides a novel strategy for treating chronic allergic airways disease	179
Leveraging thiol-functionalized biomucoadhesive hybrid nanoliposome for local therapy of ulcerative colitis	177
Versatile conductive hydrogel orchestrating neuro–immune microenvironment for rapid diabetic wound healing through peripheral nerve regeneration	170
Potentiating cancer vaccination by adjuvant-loaded cryo-shocked tumor cells	166
Early phago-/endosomal escape of platinum drugs via ROS-responsive micelles for dual cancer chemo/immunotherapy	162
Aged breast matrix bound vesicles promote breast cancer invasiveness	150
Locally delivered modified citrus pectin - a galectin-3 inhibitor shows expected anti-inflammatory and unexpected regeneration-promoting effects on repair of articular cartilage defect	150
Semiconducting polymer nanoprodrugs enable tumor-specific therapy via sono-activatable ferroptosis	149
Synergetic regulation of kupffer cells, extracellular matrix and hepatic stellate cells with versatile CXCR4-inhibiting nanocomplex for magnified therapy in liver fibrosis	145
Cascade-responsive nano-assembly for efficient photothermal-chemo synergistic inhibition of tumor metastasis by targeting cancer stem cells	142
Human macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection model	139
Extracellular matrix stiffness modulates host-bacteria interactions and antibiotic therapy of bacterial internalization	135
Myoblast deactivation within engineered human skeletal muscle creates a transcriptionally heterogeneous population of quiescent satellite-like cells	131
Programming protein phase-separation employing a modular library of intrinsically disordered precision block copolymer-like proteins creating dynamic cytoplasmatic compartmentalization	130
Multifunctional fluorescence/photoacoustic bimodal imaging of γ-glutamyltranspeptidase in liver disorders under different triggering conditions	130

Multifaceted cancer alleviation by cowpea mosaic virus in a bioprinted ovarian cancer peritoneal spheroid model	128
Editorial Board	127
Profound alterations in brain tissue linked to hypoxic episode after device implantation	126
Editorial Board	125
Editorial Board	124
Editorial Board	123
Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation	122
Editorial Note: ‘The nanoformula of zoledronic acid and calcium carbonate targets osteoclasts and reverses osteoporosis’ Biomaterials, 296 (2023), 122059	122
Maleimide as the PEG end-group promotes macrophage-targeted drug delivery of PEGylated nanoparticles in vivo by enhancing interaction with circulating erythrocytes	118
Silk sericin-based materials for biomedical applications	118
Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth	117
Rapamycin-encapsulated costimulatory ICOS/CD40L-bispecific nanoparticles restrict pathogenic helper T-B-cell interactions while in situ suppressing mTOR for lupus treatment	117
Surfactants influence polymer nanoparticle fate within the brain	116
Self-oxygenation of engineered living tissues orchestrates osteogenic commitment of mesenchymal stem cells	116
Visible light-induced simultaneous bioactive amorphous calcium phosphate mineralization and in situ crosslinking of coacervate-based injectable underwater adhesive hydrogels for enhanced bone regenera	115
An artificial membrane binding protein-polymer surfactant nanocomplex facilitates stem cell adhesion to the cartilage extracellular matrix	114
RGD density along with substrate stiffness regulate hPSC hepatocyte functionality through YAP signalling	113
Dynamic surface adapts to multiple service stages by orchestrating responsive polymers and functional peptides	109
Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and osteogenesis	108
A hypochlorite-activated strategy for realizing fluorescence turn-on, type I and type II ROS-combined photodynamic tumor ablation	105
Micropatterned gellan gum-based hydrogels tailored with laminin-derived peptides for skeletal muscle tissue engineering	105
Photosensitizer-induced HPV16 E7 nanovaccines for cervical cancer immunotherapy	104
Engineering dual catalytic nanomedicine for autophagy-augmented and ferroptosis-involved cancer nanotherapy	103
X-ray-facilitated redox cycling of nanozyme possessing peroxidase-mimicking activity for reactive oxygen species-enhanced cancer therapy	103
Editorial Board	102
Endothelin-1 enhances the regenerative capability of human bone marrow-derived mesenchymal stem cells in a sciatic nerve injury mouse model	102
Editorial Board	102
Editorial Board	101
Uncloaking cell-impermeant gold nanorods via tumor microenvironmental cathepsin B facilitates cancer cell penetration and potent radiosensitization	100
Enzymatic non-covalent synthesis of supramolecular assemblies as a general platform for bioorthogonal prodrugs activation to combat drug resistance	100
Asynchronous blockade of PD-L1 and CD155 by polymeric nanoparticles inhibits triple-negative breast cancer progression and metastasis	99
Antiadhesive nanosome elicits role of glycocalyx of tumor cell-derived exosomes in the organotropic cancer metastasis	99
The use of heparin/polycation coacervate sustain release system to compare the bone regenerative potentials of 5 BMPs using a critical sized calvarial bone defect model	99
A novel antibody-KSP inhibitor conjugate improves KSP inhibitor efficacy in vitro and in vivo	98
A bioprinted sea-and-island multicellular model for dissecting human pancreatic tumor-stroma reciprocity and adaptive metabolism	98
The driving role of the Cdk5/Tln1/FAKS732 axis in cancer cell extravasation dissected by human vascularized microfluidic models	97
Oyster mantle-derived exosomes alleviate osteoporosis by regulating bone homeostasis	97
Multifunctional silk vinyl sulfone-based hydrogel scaffolds for dynamic material-cell interactions	97
Atomic vacancies-engineered ultrathin trimetallic nanozyme with anti-inflammation and antitumor performances for intestinal disease treatment	95
P22 virus-like particles as an effective antigen delivery nanoplatform for cancer immunotherapy	95
Prolongation of graft survival via layer-by-layer assembly of collagen and immunosuppressive particles on pancreatic islets	94
Bioabsorbable, elastomer-coated magnesium alloy coils for treating saccular cerebrovascular aneurysms	94
Nanoceria-GO-intercalated multicellular spheroids revascularize and salvage critical ischemic limbs through anti-apoptotic and pro-angiogenic functions	93
Biomaterial mediated simultaneous delivery of spermine and alpha ketoglutarate modulate metabolism and innate immune cell phenotype in sepsis mouse models	93
Engineering fucoxanthin-loaded probiotics’ membrane vesicles for the dietary intervention of colitis	92
Percutaneous delivery and degradation of a shape memory elastomer poly(glycerol dodecanedioate) in porcine pulmonary arteries	92
Tumor stromal topography promotes chemoresistance in migrating breast cancer cell clusters	91
Mechano-modulation of T cells for cancer immunotherapy	91
Branched hydrophobic tails in lipid nanoparticles enhance mRNA delivery for cancer immunotherapy	90
Nanovaccine that activates the NLRP3 inflammasome enhances tumor specific activation of anti-cancer immunity	90

Nanotopography-enhanced biomimetic coating maintains bioactivity after weeks of dry storage and improves chronic neural recording	89
Dendritic polymer-functionalized nanomedicine potentiates immunotherapy via lethal energy crisis-induced PD-L1 degradation	88
Neointima abating and endothelium preserving — An adventitia-localized nanoformulation to inhibit the epigenetic writer DOT1L	88
Chemically engineering the drug release rate of a PEG-paclitaxel conjugate using click and steric hindrance chemistries for optimal efficacy	87
Functional bioengineered tissue models of neurodegenerative diseases	87
Iron phthalocyanine-derived nanozyme as dual reactive oxygen species generation accelerator for photothermally enhanced tumor catalytic therapy	87
Robust tolerogenic dendritic cells via push/pull pairing of toll-like-receptor agonists and immunomodulators reduces EAE	86
Human iPSC-derived brain endothelial microvessels in a multi-well format enable permeability screens of anti-inflammatory drugs	86
Substratum interactions modulate interplay between endothelial cell, epithelial cell, and fibroblast phenotype and immunomodulatory function	86
Calcium phosphate-based biomaterials trigger human macrophages to release extracellular traps	85
ROS-reactive PMS/PC drug delivery system improves new bone formation under diabetic conditions by promoting angiogenesis-osteogenesis coupling via down-regulating NOX2-ROS signalling axis	85