Biomaterials

Papers
(The median citation count of Biomaterials is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Editorial Board758
Editorial Board380
Breast implant silicone exposure induces immunogenic response and autoimmune markers in human periprosthetic tissue321
Engineering supramolecular dynamics of self-assembly and turnover of oncogenic microRNAs to drive their synergistic destruction in tumor models315
Antigen self-presenting dendrosomes swallowing nanovaccines boost antigens and STING agonists codelivery for cancer immunotherapy260
Systemically administered platelet-inspired nanoparticles to reduce inflammation surrounding intracortical microelectrodes233
Potentiating the effect of immunotherapy in pancreatic cancer using gas-entrapping materials231
Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain209
Pulmonary myeloid cell uptake of biodegradable nanoparticles conjugated with an anti-fibrotic agent provides a novel strategy for treating chronic allergic airways disease192
Development of human pluripotent stem cell-derived hepatic organoids as an alternative model for drug safety assessment189
A NIR-II emissive sonosensitized biotuner for pyroptosis-enhanced sonodynamic therapy of hypoxic tumors181
Antibiotics armed neutrophils as a potential therapy for brain fungal infection caused by chemotherapy-induced neutropenia177
Multifaceted cancer alleviation by cowpea mosaic virus in a bioprinted ovarian cancer peritoneal spheroid model176
Early phago-/endosomal escape of platinum drugs via ROS-responsive micelles for dual cancer chemo/immunotherapy168
Tumor stromal topography promotes chemoresistance in migrating breast cancer cell clusters161
Self-reinforced photodynamic immunostimulator to downregulate and block PD-L1 for metastatic breast cancer treatment160
Orchestrated metal-coordinated carrier-free celastrol hydrogel intensifies T cell activation and regulates response to immune checkpoint blockade for synergistic chemo-immunotherapy154
Two-dimensional nanomaterials-added dynamism in 3D printing and bioprinting of biomedical platforms: Unique opportunities and challenges146
The use of heparin/polycation coacervate sustain release system to compare the bone regenerative potentials of 5 BMPs using a critical sized calvarial bone defect model142
Inhalable DNase I@Au hybrid nanoparticles for radiation sensitization and metastasis inhibition by elimination of neutrophil extracellular traps141
A neoteric antibacterial ceria-silver nanozyme for abiotic surfaces141
Mammary tissue-derived extracellular matrix hydrogels reveal the role of irradiation in driving a pro-tumor and immunosuppressive microenvironment138
X-ray-activated nanoscintillators integrated with tumor-associated neutrophils polarization for improved radiotherapy in metastatic colorectal cancer137
Calcium phosphate-based biomaterials trigger human macrophages to release extracellular traps136
Murine macrophages or their secretome delivered in alginate dressings enhance impaired wound healing in diabetic mice133
Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine133
Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia132
“On/off”-switchable crosslinked PTX-nanoformulation with improved precise delivery for NSCLC brain metastases and restrained adverse reaction over nab-PTX131
Exosomes from hypoxic urine-derived stem cells facilitate healing of diabetic wound by targeting SERPINE1 through miR-486-5p128
Versatile conductive hydrogel orchestrating neuro–immune microenvironment for rapid diabetic wound healing through peripheral nerve regeneration127
Exosome-decorated bio-heterojunctions reduce heat and ROS transfer distance for boosted antibacterial and tumor therapy127
Rapamycin-encapsulated costimulatory ICOS/CD40L-bispecific nanoparticles restrict pathogenic helper T-B-cell interactions while in situ suppressing mTOR for lupus treatment127
LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy126
Enzymatic non-covalent synthesis of supramolecular assemblies as a general platform for bioorthogonal prodrugs activation to combat drug resistance125
Intraoperative application of intelligent, responsive, self-assembling hydrogel rectifies oxygen and energy metabolism in traumatically injured brain123
Fusogenic liposomes encapsulating mitochondria as a promising delivery system for osteoarthritis therapy123
Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage121
Biomimetic nanostructural materials based on placental amniotic membrane-derived nanofibers for self-healing and anti-adhesion during cesarean section121
Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation121
Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and osteogenesis119
Locally delivered modified citrus pectin - a galectin-3 inhibitor shows expected anti-inflammatory and unexpected regeneration-promoting effects on repair of articular cartilage defect116
Uncloaking cell-impermeant gold nanorods via tumor microenvironmental cathepsin B facilitates cancer cell penetration and potent radiosensitization110
Gradient conducting polymer surfaces with netrin-1-conjugation promote axon guidance and neuron transmission of human iPSC-derived retinal ganglion cells108
Biomaterial based implants caused remote liver fatty deposition through activated blood-derived macrophages108
Regenerative capacity of neural tissue scales with changes in tissue mechanics post injury108
Mitochondria-targeting materials and therapies for regenerative engineering108
Both non-coated and polyelectrolytically-coated intraocular collagen-alginate composite gels enhanced photoreceptor survival in retinal degeneration108
Editorial Board107
Suspension culture of human induced pluripotent stem cell-derived intestinal organoids using natural polysaccharides106
Folate conjugated nanomedicines for selective inhibition of mTOR signaling in polycystic kidneys at clinically relevant doses106
Cryogel vaccines effectively induce immune responses independent of proximity to the draining lymph nodes106
Calcium phosphate nanoclusters modify periodontium remodeling and minimize orthodontic relapse105
Effect of carbon nanomaterial dimension on the functional activity and degeneration of neurons105
A supramolecular polymer-collagen microparticle slurry for bone regeneration with minimal growth factor105
Corrigendum to ‘Bioprinting 3D microfibrous scaffolds for engineering cardiac tissues and heart-on-a-chip’ [Biomaterials Volume 110, (2016) Pages 45–59]104
AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery102
Bifunctional black phosphorus quantum dots platform: Delivery and remarkable immunotherapy enhancement of STING agonist100
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis99
Patch grafting of organoids of stem/progenitors into solid organs can correct genetic-based disease states98
Galacto-oligosaccharides as an anti-bacterial and anti-invasive agent in lung infections98
Shape memory micro-anchors with magnetic guidance for precision micro-vascular deployment98
Heteroantigen-assembled nanovaccine enhances the polyfunctionality of TILs against tumor growth and metastasis96
Cr(V)–Cr(III) in-situ transition promotes ROS generation to achieve efficient cancer therapy96
Insensitivity of dental pulp stem cells migration to substrate stiffness96
Editorial Board96
Retraction notice to “Phototherapy together with it triggered immunological response for Anti-HPV treatment of oropharyngeal cancer: Removing tumor and pathogenic virus simultaneously” [Biomaterials (96
Editorial Board96
Injectable bioresponsive bone adhesive hydrogels inhibit NLRP3 inflammasome on demand to accelerate diabetic fracture healing95
Ink-jet 3D printing as a strategy for developing bespoke non-eluting biofilm resistant medical devices93
Nanoparticles targeting OPN loaded with BY1 inhibits vascular restenosis by inducing FTH1-dependent ferroptosis in vascular smooth muscle cells93
Tailoring photobiomodulation to enhance tissue regeneration93
Interactions of core cross-linked poly(2-oxazoline) and poly(2-oxazine) micelles with immune cells in human blood93
Evaluation of immobilized microspheres of Clonostachys rosea on Botrytis cinerea and tomato seedlings93
Engineering a 3D collective cancer invasion model with control over collagen fiber alignment92
Nano-enabled photosynthesis in tumours to activate lipid peroxidation for overcoming cancer resistances92
Graphene oxide-functionalized nanocomposites promote osteogenesis of human mesenchymal stem cells via enhancement of BMP-SMAD1/5 signaling pathway91
A low-energy emulsification platform based on a Diet Coke–Mentos reaction-derived bubbly flow for formulating various emulsions as drug carriers91
Omentum-on-a-chip: A multicellular, vascularized microfluidic model of the human peritoneum for the study of ovarian cancer metastases91
Polymeric nanoparticle gel for intracellular mRNA delivery and immunological reprogramming of tumors89
Glutaminolysis inhibition boosts photodynamic therapy to eliminate cancer stem cells88
Activation of the cGAS-STING pathway combined with CRISPR-Cas9 gene editing triggering long-term immunotherapy88
Rationally integrating peptide-induced targeting and multimodal therapies in a dual-shell theranostic platform for orthotopic metastatic spinal tumors88
“One-stitch” bioorthogonal prodrug activation based on cross-linked lipoic acid nanocapsules88
Biomaterials for reliable wearable health monitoring: Applications in skin and eye integration88
Intravital imaging and single cell transcriptomic analysis for engraftment of mesenchymal stem cells in an animal model of interstitial cystitis/bladder pain syndrome87
Polyprodrug nanomedicine for chemiexcitation-triggered self-augmented cancer chemotherapy and gas therapy87
Inhalable pH-responsive DNA tetrahedron nanoplatform for boosting anti-tumor immune responses against metastatic lung cancer86
Injectable and photocurable CAR-T cell formulation enhances the anti-tumor activity to melanoma in mice86
Self-preparation system using glucose oxidase-inspired nitroreductase amplification for cascade-responsive drug release and multidrug resistance reversion86
Remodeling liver microenvironment by L-arginine loaded hollow polydopamine nanoparticles for liver cirrhosis treatment85
Oxygen-vacancy-rich molybdenum carbide MXene nanonetworks for ultrasound-triggered and capturing-enhanced sonocatalytic bacteria eradication85
A physicochemical double cross-linked multifunctional hydrogel for dynamic burn wound healing: shape adaptability, injectable self-healing property and enhanced adhesion85
Self-targeting platinum(IV) amphiphilic prodrug nano-assembly as radiosensitizer for synergistic and safe chemoradiotherapy of hepatocellular carcinoma85
Wake biofilm up to enhance suicidal uptake of gallium for chronic lung infection treatment85
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy84
Corrigendum to “Multifunctional nanoparticles based on a polymeric copper chelator for combination treatment of metastatic breast cancer” [Biomaterials 195 (2019) 86–99]84
Customized blood-brain barrier shuttle peptide to increase AAV9 vector crossing the BBB and augment transduction in the brain83
Corrigendum to “Self-assembling peptide hydrogel enables instant epicardial coating of the heart with mesenchymal stromal cells for the treatment of heart failure” [Biomaterials 154 (2018) 12–23]83
Reversible blood-brain barrier opening utilizing the membrane active peptide melittin in vitro and in vivo83
Sonocatalytic oncolysis microbiota curb intrinsic microbiota lactate metabolism and blockade CD24-Siglec10 immune escape to revitalize immunological surveillance83
Adhesive peptide and polymer density modulate 3D cell traction forces within synthetic hydrogels82
Multimodal obstruction of tumorigenic energy supply via bionic nanocarriers for effective tumor therapy82
Extracellular matrix-inspired inhalable aerogels for rapid clearance of pulmonary tuberculosis82
X-ray-controllable release of carbon monoxide potentiates radiotherapy by ultrastable hybrid nanoreservoirs82
Biomimetic non-collagenous proteins-calcium phosphate complex with superior osteogenesis via regulating macrophage IL-27 secretion82
Drug-eluting immune checkpoint blockade antibody-nanoparticle conjugate enhances locoregional and systemic combination cancer immunotherapy through T lymphocyte targeting82
Cell reprogramming in a predictable manner on the superhydrophobic microwell array chip82
Corrigendum to “Dual-step irradiation strategy to sequentially destroy singlet oxygen-responsive polymeric micelles and boost photodynamic cancer therapy” [Biomater. 275 (2021) 120959]81
A rechargeable anti-thrombotic coating for blood-contacting devices81
Focused acoustic vortex-mediated sonochemotherapy for the amplification of immunogenic cell death combined with checkpoint blockade to potentiate cancer immunotherapy80
LIFU-unlocked endogenous H2S generation for enhancing atherosclerosis-specific gas-enzymatic therapy80
Self-assembling polymer-based short chain fatty acid prodrugs ameliorate non-alcoholic steatohepatitis and liver fibrosis80
Transcriptomic profiling of human mesenchymal stem cells using a pulsed electromagnetic-wave motion bioreactor system for enhanced osteogenic commitment and therapeutic potentials80
Biophysical cues of bone marrow-inspired scaffolds regulate hematopoiesis of hematopoietic stem and progenitor cells78
Electrically-driven drug delivery into deep cutaneous tissue by conductive microneedles for fungal infection eradication and protective immunity78
Engineering probiotic biohydrogen micro-factories to initiate reductive stress for boosting tumor vulnerability78
Genetically engineered cellular nanoparticles for biomedical applications77
Using computational methods to design patient-specific electrospun cardiac patches for pediatric heart failure77
A scalable and sensitive steatosis chip with long-term perfusion of in situ differentiated HepaRG organoids77
Trehalose enhanced cold atmospheric plasma-mediated cancer treatment77
Photoactive intragastric satiety-inducing device using polymeric photosensitizers for minimally invasive weight loss treatment77
Zn0.8Li0.1Sr—a biodegradable metal with high mechanical strength comparable to pure Ti for the treatment of osteoporotic bone fractures: In vitro and in vivo studies76
Harnessing human adipose-derived stromal cell chondrogenesis in vitro for enhanced endochondral ossification76
Sensorable zwitterionic antibacterial hydrogel for wound electrostimulation therapy76
Tumor-derived exosomes co-delivering aggregation-induced emission luminogens and proton pump inhibitors for tumor glutamine starvation therapy and enhanced type-I photodynamic therapy76
Drug screening by uniform patient derived colorectal cancer hydro-organoids75
Modulation of designer biomimetic matrices for optimized differentiated intestinal epithelial cultures75
An MRI-trackable therapeutic nanovaccine preventing cancer liver metastasis75
ROS-activatable biomimetic interface mediates in-situ bioenergetic remodeling of osteogenic cells for osteoporotic bone repair75
External cold atmospheric plasma-responsive on-site hydrogel for remodeling tumor immune microenvironment75
Dynamic gelatin-based hydrogels promote the proliferation and self-renewal of embryonic stem cells in long-term 3D culture75
Tuning the surface potential to reprogram immune microenvironment for bone regeneration74
Microbubbles for human diagnosis and therapy74
Double-layered adhesive microneedle bandage based on biofunctionalized mussel protein for cardiac tissue regeneration74
Polymeric coating on β-TCP scaffolds provides immobilization of small extracellular vesicles with surface-functionalization and ZEB1-Loading for bone defect repair in diabetes mellitus74
A tunable self-healing ionic hydrogel with microscopic homogeneous conductivity as a cardiac patch for myocardial infarction repair73
Spatially patterned 3D model mimics key features of cancer metastasis to bone73
Bismuth drug-inspired ultra-small dextran coated bismuth oxide nanoparticles for targeted computed tomography imaging of inflammatory bowel disease73
Electron-acceptor density adjustments for preparation conjugated polymers with NIR-II absorption and brighter NIR-II fluorescence and 1064 nm active photothermal/gas therapy73
Plant mucus-derived microgels: Blood-triggered gelation and strong hemostatic adhesion72
Enzyme-triggered transcytosis of drug carrier system for deep penetration into hepatoma tumors72
Recent development of metal-organic framework nanocomposites for biomedical applications72
Hypoxia-activated cascade nanovaccine for synergistic chemoembolization-immune therapy of hepatocellular carcinoma71
Progress in the research of nanomaterial-based exosome bioanalysis and exosome-based nanomaterials tumor therapy71
The programmed site-specific delivery of LY3200882 and PD-L1 siRNA boosts immunotherapy for triple-negative breast cancer by remodeling tumor microenvironment71
Biomimetic inducer enabled dual ferroptosis of tumor and M2-type macrophages for enhanced tumor immunotherapy71
In-silico investigation of umami peptides with receptor T1R1/T1R3 for the discovering potential targets: A combined modeling approach71
Self-assembled nano-photosensitizer for targeted, activatable, and biosafe cancer phototheranostics71
Corrigendum to “Selective binding of C-6OH sulfated hyaluronic acid to the angiogenic isoform of VEGF165” [Biomaterials 77(2016) 130–138]69
Biomaterial-mediated intracellular control of macrophages for cell therapy in pro-inflammatory and pro-fibrotic conditions69
Cell-specific ferroptosis targeting tumors while sparing immune cells69
Editorial Board69
Nanoradiosentizers with X ray-actuatable supramolecular aptamer building units for programmable immunostimulatory T cell engagement69
pH/NIR-responsive and self-healing coatings with bacteria killing, osteogenesis, and angiogenesis performances on magnesium alloy69
Editorial Board69
CEACAM1-engineered MSCs have a broad spectrum of immunomodulatory functions and therapeutic potential via cell-to-cell interaction68
Remote Co-loading of amphipathic acid drugs in neutrophil nanovesicles infilled with cholesterol mitigates lung bacterial infection and inflammation68
Black phosphorus nanosheets activate tumor immunity of glioblastoma by modulating the expression of the immunosuppressive molecule PD-L168
Developmental dynamics mimicking inversely engineered pericellular matrix for articular cartilage regeneration67
Myoblast mechanotransduction and myotube morphology is dependent on BAG3 regulation of YAP and TAZ67
Rescue of mitochondrial dysfunction through alteration of extracellular matrix composition in barth syndrome cardiac fibroblasts67
Engineering a biomimetic bone scaffold that can regulate redox homeostasis and promote osteogenesis to repair large bone defects67
Coating of cochlear implant electrodes with bioactive DNA-loaded calcium phosphate nanoparticles for the local transfection of stimulatory proteins67
Respiratory mucosal vaccination of peptide-poloxamine-DNA nanoparticles provides complete protection against lethal SARS-CoV-2 challenge67
An artificial LAMA2-GelMA hydrogel microenvironment for the development of pancreatic endocrine progenitors66
Healing through the lens of immunothrombosis: Biology-inspired, evolution-tailored, and human-engineered biomimetic therapies66
PAR2 on oral cancer cells and nociceptors contributes to oral cancer pain that can be relieved by nanoparticle-encapsulated AZ345166
Randomized peptide assemblies for enhancing immune responses to nanomaterials66
Fucoidan-functionalized polysaccharide submicroparticles loaded with alteplase for efficient targeted thrombolytic therapy65
Triple-transformable dynamic surroundings for programmed transportation of bio-vulnerable mRNA payloads towards systemic treatment of intractable solid tumors65
Discrete single-cell microRNA analysis for phenotyping the heterogeneity of acute myeloid leukemia65
An SS31-rapamycin conjugate via RBC hitchhiking for reversing acute kidney injury65
Orally delivered 2D covalent organic frameworks releasing kynurenine generate anti-inflammatory T cell responses in collagen induced arthritis mouse model65
In vivo spatiotemporal dynamics of astrocyte reactivity following neural electrode implantation64
Tumor-targeted redox-regulating and antiangiogenic phototherapeutics nanoassemblies for self-boosting phototherapy64
Biodegradable interbody cages for lumbar spine fusion: Current concepts and future directions64
Smart biomaterial platforms: Controlling and being controlled by cells63
Organic functional substance engineered living materials for biomedical applications63
Stretchable mesh microelectronics for the biointegration and stimulation of human neural organoids63
High-strength biodegradable zinc alloy implants with antibacterial and osteogenic properties for the treatment of MRSA-induced rat osteomyelitis62
Development of miR-26a-activated scaffold to promote healing of critical-sized bone defects through angiogenic and osteogenic mechanisms62
Transformable amyloid-beta mimetic peptide amphiphiles for lysosomal disruption in non-small cell lung cancer62
Dual mitigation of immunosuppression combined with photothermal inhibition for highly effective primary tumor and metastases therapy62
Human chemically-derived hepatic progenitors (hCdHs) as a source of liver organoid generation: Application in regenerative medicine, disease modeling, and toxicology testing62
Beyond antioxidation: Harnessing the CeO2 nanoparticles as a renoprotective contrast agent for in vivo spectral CT angiography62
Microfluidic nanomaterials: From synthesis to biomedical applications62
Diffusion-mediated carving of interior topologies of all-natural protein nanoparticles to tailor sustained drug release for effective breast cancer therapy61
Mechanical activation drives tenogenic differentiation of human mesenchymal stem cells in aligned dense collagen hydrogels61
Multiscale rheology of glioma cells61
Corrigendum to ‘The use of charge-coupled polymeric microparticles and micromagnets for modulating the bioavailability of orally delivered macromolecules’ [Biomaterials Volume 29 Issue 9 (2008) 5825]61
Mapping the acute time course of immune cell infiltration into an ECM hydrogel in a rat model of stroke using 19F MRI61
An oral ratiometric NIR-II fluorescent probe for reliable monitoring of gastrointestinal diseases in vivo60
Reconstructing auto tissue engineering lamellar cornea with aspartic acid modified acellular porcine corneal stroma and preconditioned limbal stem cell for corneal regeneration60
Flexible patch with printable and antibacterial conductive hydrogel electrodes for accelerated wound healing60
Label-free and non-destructive identification of naïve and primed embryonic stem cells based on differences in cellular metabolism59
Metallic artifacts-free spectral computed tomography angiography based on renal clearable bismuth chelate59
Macrophage membrane-biomimetic ROS-responsive platinum nanozyme clusters for acute kidney injury treatment59
Hybrid material mimics a hypoxic environment to promote regeneration of peripheral nerves59
‘Green’ nanotherapeutics from tea leaves for orally targeted prevention and alleviation of colon diseases59
Gellan gum-gelatin scaffolds with Ca2+ crosslinking for constructing a structured cell cultured meat model59
Generation of offspring-producing 3D ovarian organoids derived from female germline stem cells and their application in toxicological detection59
Bifunctional mesoporous HMUiO-66-NH2 nanoparticles for bone remodeling and ROS scavenging in periodontitis therapy59
Osteogenesis, hemocompatibility, and foreign body response of polyvinylidene difluoride-based composite reinforced with carbonaceous filler and higher volume of piezoelectric ceramic phase59
Neutrophils exhibit flexible migration strategies and trail formation mechanisms on varying adhesive substrates58
Editorial Board58
Antioxidative and antibacterial gallium (III)-phenolic coating for enhanced osseointegration of titanium implants via pro-osteogenesis and inhibiting osteoclastogenesis58
Microenvironment matters: In vitro 3D bone marrow niches differentially modulate survival, phenotype and drug responses of acute myeloid leukemia (AML) cells58
Synchronously boosting type-I photodynamic and photothermal efficacies via molecular manipulation for pancreatic cancer theranostics in the NIR-II window58
Maturation of iPSC-derived cardiomyocytes in a heart-on-a-chip device enables modeling of dilated cardiomyopathy caused by R222Q-SCN5A mutation58
Controlling dielectric loss of biodegradable black phosphorus nanosheets by iron-ion-modification for imaging-guided microwave thermoacoustic therapy58
Editorial Board58
Cyclic catalysis of intratumor Fe3+/2+ initiated by a hollow mesoporous iron sesquioxide nanoparticle for ferroptosis therapy of large tumors58
Engineered VNP20009 expressing IL-15&15Rα augments anti-tumor immunity for bladder cancer treatment57
Nanocontroller-mediated dissolving hydrogel that can sustainably release cold-mimetic menthol to induce adipocyte browning for treating obesity and its related metabolic disorders57
Extended longevity geometrically-inverted proximal tubule organoids57
Corrigendum to A hypochlorite-activated strategy for realizing fluorescence turn-on, type I and type II ROS-combined photodynamic tumor ablation Biomaterials Volume 297, 122108, (2023)57
Amyloid fibril-based thixotropic hydrogels for modeling of tumor spheroids in vitro57
A carrier-free ultrasound-responsive polyphenol nanonetworks with enhanced sonodynamic-immunotherapy for synergistic therapy of breast cancer56
Biomimetic nanoparticle synchronizing pyroptosis induction and mitophagy inhibition for anti-tumor therapy56
Biologically logic-gated Trojan-horse strategy for personalized triple-negative breast cancer precise therapy by selective ferroptosis and STING pathway provoking56
Image analyses for engineering advanced tissue biomanufacturing processes56
Blood brain barrier-targeted delivery of double selenium nanospheres ameliorates neural ferroptosis in Alzheimer's disease56
Ultrasound molecular imaging of p32 protein translocation for evaluation of tumor metastasis56
A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model56
Specific diagnosis of lymph node micrometastasis in breast cancer by targeting activatable near-infrared fluorescence imaging56
Core-shell hydrogel microfiber-expanded pluripotent stem cell-derived lung progenitors applicable to lung reconstruction in vivo56
Functional imaging and targeted drug delivery in mice and patient tumors with a cell nucleolus-localizing and tumor-targeting peptide56
3D printed colloidal biomaterials based on photo-reactive gelatin nanoparticles55
Planar amorphous silicon carbide microelectrode arrays for chronic recording in rat motor cortex55
3D-Printed proangiogenic patches of photo-crosslinked gelatin and polyurethane hydrogels laden with vascular cells for treating vascular ischemic diseases55
Regulating tumor cells to awaken T cell antitumor function and enhance melanoma immunotherapy55
Intranasal delivery of liposome encapsulated flavonoids ameliorates l-DOPA induced dyskinesia in hemiparkinsonian mice54
Genetically engineered CD276-anchoring biomimetic nanovesicles target senescent escaped tumor cells to overcome chemoresistant and immunosuppressive breast cancer54
Biophysical matrix cues from the regenerating niche direct muscle stem cell fate in engineered microenvironments54
Mononuclear phagocyte system blockade using extracellular vesicles modified with CD47 on membrane surface for myocardial infarction reperfusion injury treatment54
Precision medicine-guided co-delivery of ASPN siRNA and oxaliplatin by nanoparticles to overcome chemoresistance of colorectal cancer54
Reappraisal of anticancer nanomedicine design criteria in three types of preclinical cancer models for better clinical translation54
Inhibition of glycolysis in the presence of antigen generates suppressive antigen-specific responses and restrains rheumatoid arthritis in mice53
Biodegradable magnesium combined with distraction osteogenesis synergistically stimulates bone tissue regeneration via CGRP-FAK-VEGF signaling axis53
Self-powered smart patch promotes skin nerve regeneration and sensation restoration by delivering biological-electrical signals in program53
Biomimetic ion nanochannels for sensing umami substances53
Spatial patterning of phenotypically distinct microtissues to engineer osteochondral grafts for biological joint resurfacing53
Bioactive glass nanoparticles inhibit osteoclast differentiation and osteoporotic bone loss by activating lncRNA NRON expression in the extracellular vesicles derived from bone marrow mesenchymal stem52
A nitric oxide-eluting and REDV peptide-conjugated coating promotes vascular healing52
An injectable peptide hydrogel with excellent self-healing ability to continuously release salvianolic acid B for myocardial infarction52
2D Janus carrier-enabled trojan horse: Gallium delivery for the sequential therapy of biofilm associated infection52
Regional and disease specific human lung extracellular matrix composition52
The safe and effective intraperitoneal chemotherapy with cathepsin B-specific doxorubicin prodrug nanoparticles in ovarian cancer with peritoneal carcinomatosis52
T-cell engaging poly(lactic-co-glycolic acid) nanoparticles as a modular platform to induce a potent cytotoxic immunogenic response against PD-L1 overexpressing cancer52
A strategy for screening novel umami dipeptides based on common feature pharmacophore and molecular docking52
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