Biomaterials

Papers
(The median citation count of Biomaterials is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Corrigendum to ‘Optimal electrical stimulation boosts stem cell therapy in nerve regeneration’ [Biomaterials 181 (2018) 18758]494
Editorial Board229
Editorial Board225
Tailoring extracellular matrix niches: Impact of glycosaminoglycan content on multiple differentiation of human mesenchymal stem cells218
Potentiating the effect of immunotherapy in pancreatic cancer using gas-entrapping materials213
Hepatic endoplasmic reticulum-derived nanodiscs for broad-spectrum drug detoxification212
Engineering supramolecular dynamics of self-assembly and turnover of oncogenic microRNAs to drive their synergistic destruction in tumor models200
Gradient-driven deep penetration of self-electrophoretic nanoparticles in acidic tumor microenvironments for enhanced antitumor therapy193
Multifaceted cancer alleviation by cowpea mosaic virus in a bioprinted ovarian cancer peritoneal spheroid model184
Two-dimensional nanomaterials-added dynamism in 3D printing and bioprinting of biomedical platforms: Unique opportunities and challenges183
Biomimetic nanostructural materials based on placental amniotic membrane-derived nanofibers for self-healing and anti-adhesion during cesarean section175
Uncloaking cell-impermeant gold nanorods via tumor microenvironmental cathepsin B facilitates cancer cell penetration and potent radiosensitization174
Self-reinforced photodynamic immunostimulator to downregulate and block PD-L1 for metastatic breast cancer treatment172
Smearable CQD-entrapped hydrogel with sensitive pH response and photodynamic antibacterial properties for visual intelligent wound monitoring171
Selective recognition of bacterial phospholipids by antimicrobial peptides: Employing a host-guest-mediated competitive inhibition strategy165
Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation160
Breast implant silicone exposure induces immunogenic response and autoimmune markers in human periprosthetic tissue159
Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain156
Rapamycin-encapsulated costimulatory ICOS/CD40L-bispecific nanoparticles restrict pathogenic helper T-B-cell interactions while in situ suppressing mTOR for lupus treatment154
Investigation of the protein corona and biodistribution profile of polymeric nanoparticles for intra-amniotic delivery153
Antigen self-presenting dendrosomes swallowing nanovaccines boost antigens and STING agonists codelivery for cancer immunotherapy150
Engineered micro-structured biomimetic material for modelling the outer blood-retinal barrier140
Bio-orthogonal-labeled exosomes reveals specific distribution in vivo and provides potential application in ARDS therapy138
Calcium phosphate-based biomaterials trigger human macrophages to release extracellular traps136
“On/off”-switchable crosslinked PTX-nanoformulation with improved precise delivery for NSCLC brain metastases and restrained adverse reaction over nab-PTX135
The use of heparin/polycation coacervate sustain release system to compare the bone regenerative potentials of 5 BMPs using a critical sized calvarial bone defect model134
Locally delivered modified citrus pectin - a galectin-3 inhibitor shows expected anti-inflammatory and unexpected regeneration-promoting effects on repair of articular cartilage defect130
Vacancies-rich Z-scheme VdW heterojunction as H2S-sensitized synergistic therapeutic nanoplatform against refractory biofilm infections129
Exosomes from hypoxic urine-derived stem cells facilitate healing of diabetic wound by targeting SERPINE1 through miR-486-5p127
A NIR-II emissive sonosensitized biotuner for pyroptosis-enhanced sonodynamic therapy of hypoxic tumors127
Exosome-decorated bio-heterojunctions reduce heat and ROS transfer distance for boosted antibacterial and tumor therapy125
LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy122
Murine macrophages or their secretome delivered in alginate dressings enhance impaired wound healing in diabetic mice121
Development of human pluripotent stem cell-derived hepatic organoids as an alternative model for drug safety assessment118
Gel@CAT-L hydrogel mediates mitochondrial unfolded protein response to regulate reactive oxygen species and mitochondrial homeostasis in osteoarthritis118
X-ray-activated nanoscintillators integrated with tumor-associated neutrophils polarization for improved radiotherapy in metastatic colorectal cancer117
Polydopamine nanoparticle-enhanced stem cell spheroid-derived decellularized extracellular matrix with antioxidant and tissue-adhesive properties for brain repair116
Fusogenic liposomes encapsulating mitochondria as a promising delivery system for osteoarthritis therapy115
A neoteric antibacterial ceria-silver nanozyme for abiotic surfaces113
Systemically administered platelet-inspired nanoparticles to reduce inflammation surrounding intracortical microelectrodes113
Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine113
Tumor stromal topography promotes chemoresistance in migrating breast cancer cell clusters112
Amplification of cGAS-STING pathway with “single-molecule multitarget” nanoparticles for chemo-immunotherapy of ovarian cancer110
Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage109
Intraoperative application of intelligent, responsive, self-assembling hydrogel rectifies oxygen and energy metabolism in traumatically injured brain109
Versatile conductive hydrogel orchestrating neuro–immune microenvironment for rapid diabetic wound healing through peripheral nerve regeneration109
Mammary tissue-derived extracellular matrix hydrogels reveal the role of irradiation in driving a pro-tumor and immunosuppressive microenvironment106
Inhalable DNase I@Au hybrid nanoparticles for radiation sensitization and metastasis inhibition by elimination of neutrophil extracellular traps105
Orchestrated metal-coordinated carrier-free celastrol hydrogel intensifies T cell activation and regulates response to immune checkpoint blockade for synergistic chemo-immunotherapy104
Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and osteogenesis104
Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia104
Biomaterial based implants caused remote liver fatty deposition through activated blood-derived macrophages101
Metal-polyphenol nanocomposite hybrid hydrogel: A multifunctional platform for treating diabetic foot ulcers through metabolic microenvironment reprogramming101
Editorial Board101
Editorial Board101
Corrigendum to ‘Bioprinting 3D microfibrous scaffolds for engineering cardiac tissues and heart-on-a-chip’ [Biomaterials Volume 110, (2016) Pages 45–59]101
Gradient conducting polymer surfaces with netrin-1-conjugation promote axon guidance and neuron transmission of human iPSC-derived retinal ganglion cells100
Suspension culture of human induced pluripotent stem cell-derived intestinal organoids using natural polysaccharides100
Tailoring the therapeutic potential of stem cell spheroid-derived decellularized ECM through post-decellularization BDNF incorporation to enhance brain repair100
Editorial Board100
Engineering adeno-associated viral vectors for CRISPR/Cas based in vivo therapeutic genome editing100
Nano-enabled photosynthesis in tumours to activate lipid peroxidation for overcoming cancer resistances99
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis99
Ink-jet 3D printing as a strategy for developing bespoke non-eluting biofilm resistant medical devices98
A supramolecular polymer-collagen microparticle slurry for bone regeneration with minimal growth factor98
Heavy-atom-effect enhanced singlet oxygen generation of carbon dots for lipid-targeting tumor photodynamic therapy inducing ferroptosis97
A low-energy emulsification platform based on a Diet Coke–Mentos reaction-derived bubbly flow for formulating various emulsions as drug carriers97
Cryogel vaccines effectively induce immune responses independent of proximity to the draining lymph nodes97
Both non-coated and polyelectrolytically-coated intraocular collagen-alginate composite gels enhanced photoreceptor survival in retinal degeneration96
Therapeutic potential of urinary extracellular vesicles in delivering functional proteins and modulating gene expression for genetic kidney disease96
Patch grafting of organoids of stem/progenitors into solid organs can correct genetic-based disease states92
Heteroantigen-assembled nanovaccine enhances the polyfunctionality of TILs against tumor growth and metastasis92
Nanoparticles targeting OPN loaded with BY1 inhibits vascular restenosis by inducing FTH1-dependent ferroptosis in vascular smooth muscle cells92
Folate conjugated nanomedicines for selective inhibition of mTOR signaling in polycystic kidneys at clinically relevant doses90
Calcium phosphate nanoclusters modify periodontium remodeling and minimize orthodontic relapse90
Bone marrow adipocytes in cancer: Mechanisms, models, and therapeutic implications89
Glutaminolysis inhibition boosts photodynamic therapy to eliminate cancer stem cells89
Regenerative capacity of neural tissue scales with changes in tissue mechanics post injury89
Galacto-oligosaccharides as an anti-bacterial and anti-invasive agent in lung infections88
Evaluation of immobilized microspheres of Clonostachys rosea on Botrytis cinerea and tomato seedlings88
Polyprodrug nanomedicine for chemiexcitation-triggered self-augmented cancer chemotherapy and gas therapy87
Biomaterials for reliable wearable health monitoring: Applications in skin and eye integration87
Mechanistic insights and therapeutic applications of metal-based nanomaterials in oral infectious diseases: Current advances and future perspectives87
Activation of the cGAS-STING pathway combined with CRISPR-Cas9 gene editing triggering long-term immunotherapy86
Hybrid cell membrane coating orchestrates foreign-body reactions, anti-adhesion, and pro-regeneration in abdominal wall reconstruction85
Injectable and photocurable CAR-T cell formulation enhances the anti-tumor activity to melanoma in mice85
AAV vectors displaying bispecific DARPins enable dual-control targeted gene delivery85
Shape memory micro-anchors with magnetic guidance for precision micro-vascular deployment84
Photoactivated in-situ engineered-bacteria as an efficient H2S generator to enhance photodynamic immunotherapy via remodeling the tumor microenvironment84
Wake biofilm up to enhance suicidal uptake of gallium for chronic lung infection treatment84
Polymeric nanoparticle gel for intracellular mRNA delivery and immunological reprogramming of tumors84
Osteoclasts drive bone formation in ectopic and orthotopic environments82
Inhalable pH-responsive DNA tetrahedron nanoplatform for boosting anti-tumor immune responses against metastatic lung cancer82
Bifunctional black phosphorus quantum dots platform: Delivery and remarkable immunotherapy enhancement of STING agonist82
Self-targeting platinum(IV) amphiphilic prodrug nano-assembly as radiosensitizer for synergistic and safe chemoradiotherapy of hepatocellular carcinoma81
Mitochondria-targeting materials and therapies for regenerative engineering81
Nanozyme-functionalized microalgal biohybrid microrobots in inflammatory bowel disease treatment80
Stable intermolecular charge-transfer nanocrystals as efficient immunogenic cell death adjuvants for photoimmunotherapy against trophoblastic and recurrent tumors80
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy79
Remodeling liver microenvironment by L-arginine loaded hollow polydopamine nanoparticles for liver cirrhosis treatment79
Omentum-on-a-chip: A multicellular, vascularized microfluidic model of the human peritoneum for the study of ovarian cancer metastases78
Oxygen-vacancy-rich molybdenum carbide MXene nanonetworks for ultrasound-triggered and capturing-enhanced sonocatalytic bacteria eradication78
Editorial Board77
Intravital imaging and single cell transcriptomic analysis for engraftment of mesenchymal stem cells in an animal model of interstitial cystitis/bladder pain syndrome77
Corrigendum to “Self-assembling peptide hydrogel enables instant epicardial coating of the heart with mesenchymal stromal cells for the treatment of heart failure” [Biomaterials 154 (2018) 12–23]77
Injectable bioresponsive bone adhesive hydrogels inhibit NLRP3 inflammasome on demand to accelerate diabetic fracture healing77
A stiff bioink for hybrid bioprinting of vascularized bone tissue with enhanced mechanical properties77
Albumin nanocomplex of BCL-2/xL inhibitor reduced platelet toxicity and improved anticancer efficacy in myeloproliferative neoplasm and lymphoma77
Tailoring photobiomodulation to enhance tissue regeneration77
Corrigendum to “Multifunctional nanoparticles based on a polymeric copper chelator for combination treatment of metastatic breast cancer” [Biomaterials 195 (2019) 86–99]76
Corrigendum to “Dual-step irradiation strategy to sequentially destroy singlet oxygen-responsive polymeric micelles and boost photodynamic cancer therapy” [Biomater. 275 (2021) 120959]76
Engineering probiotic biohydrogen micro-factories to initiate reductive stress for boosting tumor vulnerability75
Enzyme-triggered transcytosis of drug carrier system for deep penetration into hepatoma tumors75
Modulation of designer biomimetic matrices for optimized differentiated intestinal epithelial cultures75
Microbubbles for human diagnosis and therapy75
The programmed site-specific delivery of LY3200882 and PD-L1 siRNA boosts immunotherapy for triple-negative breast cancer by remodeling tumor microenvironment75
External cold atmospheric plasma-responsive on-site hydrogel for remodeling tumor immune microenvironment75
ROS-activatable biomimetic interface mediates in-situ bioenergetic remodeling of osteogenic cells for osteoporotic bone repair75
Editorial Board75
Sonocatalytic oncolysis microbiota curb intrinsic microbiota lactate metabolism and blockade CD24-Siglec10 immune escape to revitalize immunological surveillance74
Cell reprogramming in a predictable manner on the superhydrophobic microwell array chip74
Dynamic gelatin-based hydrogels promote the proliferation and self-renewal of embryonic stem cells in long-term 3D culture73
Transcriptomic profiling of human mesenchymal stem cells using a pulsed electromagnetic-wave motion bioreactor system for enhanced osteogenic commitment and therapeutic potentials73
Harnessing human adipose-derived stromal cell chondrogenesis in vitro for enhanced endochondral ossification73
Biophysical cues of bone marrow-inspired scaffolds regulate hematopoiesis of hematopoietic stem and progenitor cells72
Peritoneum-inspired adaptive hydrogel sheath orchestrating long-term lubrication and antibacterial properties for drainage tube intubation72
Biomimetic non-collagenous proteins-calcium phosphate complex with superior osteogenesis via regulating macrophage IL-27 secretion72
Using computational methods to design patient-specific electrospun cardiac patches for pediatric heart failure72
CD38-targeted antibody-polymer drug conjugates for enhanced treatment of multiple myeloma72
Spatially patterned 3D model mimics key features of cancer metastasis to bone71
Focused acoustic vortex-mediated sonochemotherapy for the amplification of immunogenic cell death combined with checkpoint blockade to potentiate cancer immunotherapy71
Photoactive intragastric satiety-inducing device using polymeric photosensitizers for minimally invasive weight loss treatment71
Customized blood-brain barrier shuttle peptide to increase AAV9 vector crossing the BBB and augment transduction in the brain71
Bioprinting spatially guided functional 3D neural circuits with agarose-xanthan gum copolymer hydrogels71
Bismuth drug-inspired ultra-small dextran coated bismuth oxide nanoparticles for targeted computed tomography imaging of inflammatory bowel disease70
Self-assembled nano-photosensitizer for targeted, activatable, and biosafe cancer phototheranostics70
Polymeric coating on β-TCP scaffolds provides immobilization of small extracellular vesicles with surface-functionalization and ZEB1-Loading for bone defect repair in diabetes mellitus69
In-silico investigation of umami peptides with receptor T1R1/T1R3 for the discovering potential targets: A combined modeling approach69
Hypoxia-activated cascade nanovaccine for synergistic chemoembolization-immune therapy of hepatocellular carcinoma68
Tumor-derived exosomes co-delivering aggregation-induced emission luminogens and proton pump inhibitors for tumor glutamine starvation therapy and enhanced type-I photodynamic therapy68
Electron-acceptor density adjustments for preparation conjugated polymers with NIR-II absorption and brighter NIR-II fluorescence and 1064 nm active photothermal/gas therapy68
Targeting the senescent surfaceome through DPP4 antibody-functionalized nanoparticles. An application to cancer therapy68
Biomimetic inducer enabled dual ferroptosis of tumor and M2-type macrophages for enhanced tumor immunotherapy67
Dynamic hydration driven adhesiveness self-reinforcement of powdery protein for rapid artery hemostasis67
CD44 and αV-integrins dual-targeting bimetallic nanozymes for lung adenocarcinoma therapy via NIR-enhanced ferroptosis/apoptosis67
Self-assembling polymer-based short chain fatty acid prodrugs ameliorate non-alcoholic steatohepatitis and liver fibrosis67
LIFU-unlocked endogenous H2S generation for enhancing atherosclerosis-specific gas-enzymatic therapy66
Tuning the surface potential to reprogram immune microenvironment for bone regeneration66
Electrically-driven drug delivery into deep cutaneous tissue by conductive microneedles for fungal infection eradication and protective immunity66
Adhesive peptide and polymer density modulate 3D cell traction forces within synthetic hydrogels65
Elastic sac-shaped hydrogel dressing with responsive antibacterial and pro-healing in movable wounds via MOF activated ink spraying65
X-ray-controllable release of carbon monoxide potentiates radiotherapy by ultrastable hybrid nanoreservoirs65
Genetically engineered cellular nanoparticles for biomedical applications65
Cell-specific ferroptosis targeting tumors while sparing immune cells65
Stromal cell-derived factor-encapsulated nanoparticles target ischemic myocardium and attenuate myocardial injury via proangiogenic effects64
pH/NIR-responsive and self-healing coatings with bacteria killing, osteogenesis, and angiogenesis performances on magnesium alloy64
Sensorable zwitterionic antibacterial hydrogel for wound electrostimulation therapy64
Nanoradiosentizers with X ray-actuatable supramolecular aptamer building units for programmable immunostimulatory T cell engagement64
Trehalose enhanced cold atmospheric plasma-mediated cancer treatment64
Recent development of metal-organic framework nanocomposites for biomedical applications64
Corrigendum to ‘The use of charge-coupled polymeric microparticles and micromagnets for modulating the bioavailability of orally delivered macromolecules’ [Biomaterials Volume 29 Issue 9 (2008) 5825]64
Triple-transformable dynamic surroundings for programmed transportation of bio-vulnerable mRNA payloads towards systemic treatment of intractable solid tumors64
Plant mucus-derived microgels: Blood-triggered gelation and strong hemostatic adhesion64
Harnessing the Death Switch: Empowering Cancer Therapy by Modulating the Apoptosis-Pyroptosis Transition64
Rescue of mitochondrial dysfunction through alteration of extracellular matrix composition in barth syndrome cardiac fibroblasts64
Probiotic domestication and engineering enable one-shot treatment for bladder mucosal repair63
Diffusion-mediated carving of interior topologies of all-natural protein nanoparticles to tailor sustained drug release for effective breast cancer therapy63
CEACAM1-engineered MSCs have a broad spectrum of immunomodulatory functions and therapeutic potential via cell-to-cell interaction62
Respiratory mucosal vaccination of peptide-poloxamine-DNA nanoparticles provides complete protection against lethal SARS-CoV-2 challenge62
Tumor-targeted redox-regulating and antiangiogenic phototherapeutics nanoassemblies for self-boosting phototherapy62
Corrigendum to “Selective binding of C-6OH sulfated hyaluronic acid to the angiogenic isoform of VEGF165” [Biomaterials 77(2016) 130–138]62
Orally delivered 2D covalent organic frameworks releasing kynurenine generate anti-inflammatory T cell responses in collagen induced arthritis mouse model62
Discrete single-cell microRNA analysis for phenotyping the heterogeneity of acute myeloid leukemia62
Mapping the acute time course of immune cell infiltration into an ECM hydrogel in a rat model of stroke using 19F MRI62
Label-free and non-destructive identification of naïve and primed embryonic stem cells based on differences in cellular metabolism62
In vivo spatiotemporal dynamics of astrocyte reactivity following neural electrode implantation62
Beyond antioxidation: Harnessing the CeO2 nanoparticles as a renoprotective contrast agent for in vivo spectral CT angiography61
Human chemically-derived hepatic progenitors (hCdHs) as a source of liver organoid generation: Application in regenerative medicine, disease modeling, and toxicology testing61
Organic functional substance engineered living materials for biomedical applications61
PAR2 on oral cancer cells and nociceptors contributes to oral cancer pain that can be relieved by nanoparticle-encapsulated AZ345161
Black phosphorus nanosheets activate tumor immunity of glioblastoma by modulating the expression of the immunosuppressive molecule PD-L161
Extracellular matrix glycation epigenetically regulates brain aging and neurodegeneration in the in vitro aged neurovascular model61
Reconstructing auto tissue engineering lamellar cornea with aspartic acid modified acellular porcine corneal stroma and preconditioned limbal stem cell for corneal regeneration61
Remote Co-loading of amphipathic acid drugs in neutrophil nanovesicles infilled with cholesterol mitigates lung bacterial infection and inflammation61
An artificial LAMA2-GelMA hydrogel microenvironment for the development of pancreatic endocrine progenitors61
An SS31-rapamycin conjugate via RBC hitchhiking for reversing acute kidney injury61
Manganese-coordinated nanoparticles loaded with CHK1 inhibitor dually activate cGAS-STING pathway and enhance efficacy of immune checkpoint therapy61
Maturation of iPSC-derived cardiomyocytes in a heart-on-a-chip device enables modeling of dilated cardiomyopathy caused by R222Q-SCN5A mutation60
Cyclic catalysis of intratumor Fe3+/2+ initiated by a hollow mesoporous iron sesquioxide nanoparticle for ferroptosis therapy of large tumors60
Developmental dynamics mimicking inversely engineered pericellular matrix for articular cartilage regeneration60
Stretchable mesh microelectronics for the biointegration and stimulation of human neural organoids60
A Di-aptamer-functionalized scaffold promotes bone regeneration by facilitating the selective retention of MSCs and EPCs and then promoting crosstalk between osteogenesis and angiogenesis59
Smart biomaterial platforms: Controlling and being controlled by cells59
An oral ratiometric NIR-II fluorescent probe for reliable monitoring of gastrointestinal diseases in vivo59
Biomaterial-mediated intracellular control of macrophages for cell therapy in pro-inflammatory and pro-fibrotic conditions59
Flexible patch with printable and antibacterial conductive hydrogel electrodes for accelerated wound healing59
Gellan gum-gelatin scaffolds with Ca2+ crosslinking for constructing a structured cell cultured meat model58
Microfluidic nanomaterials: From synthesis to biomedical applications58
Metallic artifacts-free spectral computed tomography angiography based on renal clearable bismuth chelate58
Development of miR-26a-activated scaffold to promote healing of critical-sized bone defects through angiogenic and osteogenic mechanisms58
Osteogenesis, hemocompatibility, and foreign body response of polyvinylidene difluoride-based composite reinforced with carbonaceous filler and higher volume of piezoelectric ceramic phase58
Biodegradable interbody cages for lumbar spine fusion: Current concepts and future directions57
Engineering a biomimetic bone scaffold that can regulate redox homeostasis and promote osteogenesis to repair large bone defects57
High-strength biodegradable zinc alloy implants with antibacterial and osteogenic properties for the treatment of MRSA-induced rat osteomyelitis56
Mechanical activation drives tenogenic differentiation of human mesenchymal stem cells in aligned dense collagen hydrogels56
Editorial Board56
Editorial Board56
Bifunctional mesoporous HMUiO-66-NH2 nanoparticles for bone remodeling and ROS scavenging in periodontitis therapy56
Macrophage membrane-biomimetic ROS-responsive platinum nanozyme clusters for acute kidney injury treatment56
Controlling dielectric loss of biodegradable black phosphorus nanosheets by iron-ion-modification for imaging-guided microwave thermoacoustic therapy56
Synchronously boosting type-I photodynamic and photothermal efficacies via molecular manipulation for pancreatic cancer theranostics in the NIR-II window56
Antioxidative and antibacterial gallium (III)-phenolic coating for enhanced osseointegration of titanium implants via pro-osteogenesis and inhibiting osteoclastogenesis56
Corrigendum to A hypochlorite-activated strategy for realizing fluorescence turn-on, type I and type II ROS-combined photodynamic tumor ablation Biomaterials Volume 297, 122108, (2023)56
Cost-effective yet high-performance ionizable lipids for mRNA-lipid nanoparticle vaccines55
Image analyses for engineering advanced tissue biomanufacturing processes55
Neutrophils exhibit flexible migration strategies and trail formation mechanisms on varying adhesive substrates55
Extended longevity geometrically-inverted proximal tubule organoids55
Nanoparticles-mediated intratumoral gene editing targeting PD-L1 and Galectin-9 for improved cancer immunotherapy55
Specific diagnosis of lymph node micrometastasis in breast cancer by targeting activatable near-infrared fluorescence imaging55
Structure-oriented design strategy to construct NIR AIEgens to selectively combat gram (+) multidrug-resistant bacteria in vivo55
Harnessing in situ glutathione for effective ROS generation and tumor suppression via nanohybrid-mediated catabolism dynamic therapy55
3D-Printed proangiogenic patches of photo-crosslinked gelatin and polyurethane hydrogels laden with vascular cells for treating vascular ischemic diseases55
T-cell engaging poly(lactic-co-glycolic acid) nanoparticles as a modular platform to induce a potent cytotoxic immunogenic response against PD-L1 overexpressing cancer55
NIR-II imaging guided on-site size variable clustered nanosystem to potentiate sonodynamic therapy in deep-seated tumors54
A carrier-free ultrasound-responsive polyphenol nanonetworks with enhanced sonodynamic-immunotherapy for synergistic therapy of breast cancer54
The genetic background determines material-induced bone formation through the macrophage-osteoclast axis54
Autologous tumoral esterase-driven therapeutic polymers sequentially orchestrated antigen-induction, STING activation and anti-angiogenesis for systemic cancer immune therapy54
Significantly enhanced capture efficiency of cell-imprinted material for circulating tumor cells via a flexible and ultra-strong double-armed phenylboronic acid design54
2D Janus carrier-enabled trojan horse: Gallium delivery for the sequential therapy of biofilm associated infection54
Multifunctional elastomer cardiac patches for preventing left ventricle remodeling after myocardial infarction in vivo54
Self-powered smart patch promotes skin nerve regeneration and sensation restoration by delivering biological-electrical signals in program53
Precision medicine-guided co-delivery of ASPN siRNA and oxaliplatin by nanoparticles to overcome chemoresistance of colorectal cancer53
Genetically engineered CD276-anchoring biomimetic nanovesicles target senescent escaped tumor cells to overcome chemoresistant and immunosuppressive breast cancer53
Bioactive glass nanoparticles inhibit osteoclast differentiation and osteoporotic bone loss by activating lncRNA NRON expression in the extracellular vesicles derived from bone marrow mesenchymal stem53
Nanocontroller-mediated dissolving hydrogel that can sustainably release cold-mimetic menthol to induce adipocyte browning for treating obesity and its related metabolic disorders53
A nitric oxide-eluting and REDV peptide-conjugated coating promotes vascular healing52
Biologically logic-gated Trojan-horse strategy for personalized triple-negative breast cancer precise therapy by selective ferroptosis and STING pathway provoking52
Biomimetic ion nanochannels for sensing umami substances52
A strategy for screening novel umami dipeptides based on common feature pharmacophore and molecular docking52
Amyloid fibril-based thixotropic hydrogels for modeling of tumor spheroids in vitro52
Regulating tumor cells to awaken T cell antitumor function and enhance melanoma immunotherapy52
Advances in the application of smart materials in the treatment of ophthalmic diseases52
Reprogramming peritoneal macrophages with outer membrane vesicle-coated PLGA nanoparticles for endometriosis prevention52
A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model52
Ultrasound molecular imaging of p32 protein translocation for evaluation of tumor metastasis52
Planar amorphous silicon carbide microelectrode arrays for chronic recording in rat motor cortex51
Counteracting immunodepression by extracellular matrix hydrogel to promote brain tissue remodeling and neurological function recovery after traumatic brain injury51
Regional and disease specific human lung extracellular matrix composition51
Duo-nano exosome encapsulating hydrogel boosts wound healing across xenogenic and allogenic models51
Biomimetic nanoparticle synchronizing pyroptosis induction and mitophagy inhibition for anti-tumor therapy51
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