Biomaterials

Papers
(The median citation count of Biomaterials is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Corrigendum to ‘Engineered cell-laden human protein-based elastomer’ [34 (2013), 5496–5505]688
Design and development of novel self-assembled catechol-modified bile acid conjugates as pH-responsive apical sodium-dependent bile acid transporter targeting nanoparticles346
A functional 3D full-thickness model for comprehending the interaction between airway epithelium and connective tissue in cystic fibrosis300
Retraction notice to “Viability and proliferation of rat MSCs on adhesion protein-modified PET and PU scaffolds” [Biomaterials 33/12 (2012) 8094–8103]294
Restoring mammary gland structures and functions with autogenous cell therapy237
Nanoassembly of doxorubicin-conjugated polyphosphoester and siRNA simultaneously elicited macrophage- and T cell- mediated anticancer immune response for cancer therapy218
Acoustic-holography-patterned primary hepatocytes possess liver functions210
Dynamic injectable tissue adhesives with strong adhesion and rapid self-healing for regeneration of large muscle injury204
Recombinant programmed cell death protein 1 functions as an immune check point blockade and enhances anti-cancer immunity187
Bioorthogonal chemistry and illumination controlled programmed size-changeable nanomedicine for synergistic photodynamic and hypoxia-activated therapy183
Pulmonary myeloid cell uptake of biodegradable nanoparticles conjugated with an anti-fibrotic agent provides a novel strategy for treating chronic allergic airways disease179
Leveraging thiol-functionalized biomucoadhesive hybrid nanoliposome for local therapy of ulcerative colitis177
Versatile conductive hydrogel orchestrating neuro–immune microenvironment for rapid diabetic wound healing through peripheral nerve regeneration170
Potentiating cancer vaccination by adjuvant-loaded cryo-shocked tumor cells166
Early phago-/endosomal escape of platinum drugs via ROS-responsive micelles for dual cancer chemo/immunotherapy162
Locally delivered modified citrus pectin - a galectin-3 inhibitor shows expected anti-inflammatory and unexpected regeneration-promoting effects on repair of articular cartilage defect150
Aged breast matrix bound vesicles promote breast cancer invasiveness150
Semiconducting polymer nanoprodrugs enable tumor-specific therapy via sono-activatable ferroptosis149
Synergetic regulation of kupffer cells, extracellular matrix and hepatic stellate cells with versatile CXCR4-inhibiting nanocomplex for magnified therapy in liver fibrosis145
Cascade-responsive nano-assembly for efficient photothermal-chemo synergistic inhibition of tumor metastasis by targeting cancer stem cells142
Human macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection model139
Extracellular matrix stiffness modulates host-bacteria interactions and antibiotic therapy of bacterial internalization135
Myoblast deactivation within engineered human skeletal muscle creates a transcriptionally heterogeneous population of quiescent satellite-like cells131
Programming protein phase-separation employing a modular library of intrinsically disordered precision block copolymer-like proteins creating dynamic cytoplasmatic compartmentalization130
Multifunctional fluorescence/photoacoustic bimodal imaging of γ-glutamyltranspeptidase in liver disorders under different triggering conditions130
Multifaceted cancer alleviation by cowpea mosaic virus in a bioprinted ovarian cancer peritoneal spheroid model128
Editorial Board127
Profound alterations in brain tissue linked to hypoxic episode after device implantation126
Editorial Board125
Editorial Board124
Editorial Board123
Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation122
Editorial Note: ‘The nanoformula of zoledronic acid and calcium carbonate targets osteoclasts and reverses osteoporosis’ Biomaterials, 296 (2023), 122059122
Maleimide as the PEG end-group promotes macrophage-targeted drug delivery of PEGylated nanoparticles in vivo by enhancing interaction with circulating erythrocytes118
Silk sericin-based materials for biomedical applications118
Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth117
Rapamycin-encapsulated costimulatory ICOS/CD40L-bispecific nanoparticles restrict pathogenic helper T-B-cell interactions while in situ suppressing mTOR for lupus treatment117
Surfactants influence polymer nanoparticle fate within the brain116
Self-oxygenation of engineered living tissues orchestrates osteogenic commitment of mesenchymal stem cells116
Visible light-induced simultaneous bioactive amorphous calcium phosphate mineralization and in situ crosslinking of coacervate-based injectable underwater adhesive hydrogels for enhanced bone regenera115
An artificial membrane binding protein-polymer surfactant nanocomplex facilitates stem cell adhesion to the cartilage extracellular matrix114
RGD density along with substrate stiffness regulate hPSC hepatocyte functionality through YAP signalling113
Dynamic surface adapts to multiple service stages by orchestrating responsive polymers and functional peptides109
Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and osteogenesis108
Micropatterned gellan gum-based hydrogels tailored with laminin-derived peptides for skeletal muscle tissue engineering105
A hypochlorite-activated strategy for realizing fluorescence turn-on, type I and type II ROS-combined photodynamic tumor ablation105
Photosensitizer-induced HPV16 E7 nanovaccines for cervical cancer immunotherapy104
X-ray-facilitated redox cycling of nanozyme possessing peroxidase-mimicking activity for reactive oxygen species-enhanced cancer therapy103
Engineering dual catalytic nanomedicine for autophagy-augmented and ferroptosis-involved cancer nanotherapy103
Editorial Board102
Editorial Board102
Endothelin-1 enhances the regenerative capability of human bone marrow-derived mesenchymal stem cells in a sciatic nerve injury mouse model102
Editorial Board101
Enzymatic non-covalent synthesis of supramolecular assemblies as a general platform for bioorthogonal prodrugs activation to combat drug resistance100
Uncloaking cell-impermeant gold nanorods via tumor microenvironmental cathepsin B facilitates cancer cell penetration and potent radiosensitization100
The use of heparin/polycation coacervate sustain release system to compare the bone regenerative potentials of 5 BMPs using a critical sized calvarial bone defect model99
Asynchronous blockade of PD-L1 and CD155 by polymeric nanoparticles inhibits triple-negative breast cancer progression and metastasis99
Antiadhesive nanosome elicits role of glycocalyx of tumor cell-derived exosomes in the organotropic cancer metastasis99
A novel antibody-KSP inhibitor conjugate improves KSP inhibitor efficacy in vitro and in vivo98
A bioprinted sea-and-island multicellular model for dissecting human pancreatic tumor-stroma reciprocity and adaptive metabolism98
Multifunctional silk vinyl sulfone-based hydrogel scaffolds for dynamic material-cell interactions97
The driving role of the Cdk5/Tln1/FAKS732 axis in cancer cell extravasation dissected by human vascularized microfluidic models97
Oyster mantle-derived exosomes alleviate osteoporosis by regulating bone homeostasis97
Atomic vacancies-engineered ultrathin trimetallic nanozyme with anti-inflammation and antitumor performances for intestinal disease treatment95
P22 virus-like particles as an effective antigen delivery nanoplatform for cancer immunotherapy95
Prolongation of graft survival via layer-by-layer assembly of collagen and immunosuppressive particles on pancreatic islets94
Bioabsorbable, elastomer-coated magnesium alloy coils for treating saccular cerebrovascular aneurysms94
Nanoceria-GO-intercalated multicellular spheroids revascularize and salvage critical ischemic limbs through anti-apoptotic and pro-angiogenic functions93
Biomaterial mediated simultaneous delivery of spermine and alpha ketoglutarate modulate metabolism and innate immune cell phenotype in sepsis mouse models93
Engineering fucoxanthin-loaded probiotics’ membrane vesicles for the dietary intervention of colitis92
Percutaneous delivery and degradation of a shape memory elastomer poly(glycerol dodecanedioate) in porcine pulmonary arteries92
Mechano-modulation of T cells for cancer immunotherapy91
Tumor stromal topography promotes chemoresistance in migrating breast cancer cell clusters91
Nanovaccine that activates the NLRP3 inflammasome enhances tumor specific activation of anti-cancer immunity90
Branched hydrophobic tails in lipid nanoparticles enhance mRNA delivery for cancer immunotherapy90
Nanotopography-enhanced biomimetic coating maintains bioactivity after weeks of dry storage and improves chronic neural recording89
Neointima abating and endothelium preserving — An adventitia-localized nanoformulation to inhibit the epigenetic writer DOT1L88
Dendritic polymer-functionalized nanomedicine potentiates immunotherapy via lethal energy crisis-induced PD-L1 degradation88
Iron phthalocyanine-derived nanozyme as dual reactive oxygen species generation accelerator for photothermally enhanced tumor catalytic therapy87
Chemically engineering the drug release rate of a PEG-paclitaxel conjugate using click and steric hindrance chemistries for optimal efficacy87
Functional bioengineered tissue models of neurodegenerative diseases87
Substratum interactions modulate interplay between endothelial cell, epithelial cell, and fibroblast phenotype and immunomodulatory function86
Robust tolerogenic dendritic cells via push/pull pairing of toll-like-receptor agonists and immunomodulators reduces EAE86
Human iPSC-derived brain endothelial microvessels in a multi-well format enable permeability screens of anti-inflammatory drugs86
Calcium phosphate-based biomaterials trigger human macrophages to release extracellular traps85
ROS-reactive PMS/PC drug delivery system improves new bone formation under diabetic conditions by promoting angiogenesis-osteogenesis coupling via down-regulating NOX2-ROS signalling axis85
Development of human pluripotent stem cell-derived hepatic organoids as an alternative model for drug safety assessment84
Conductive electrospun polymer improves stem cell-derived cardiomyocyte function and maturation84
Intraoperative application of intelligent, responsive, self-assembling hydrogel rectifies oxygen and energy metabolism in traumatically injured brain84
Mammary tissue-derived extracellular matrix hydrogels reveal the role of irradiation in driving a pro-tumor and immunosuppressive microenvironment84
Shikonin and chitosan-silver nanoparticles synergize against triple-negative breast cancer through RIPK3-triggered necroptotic immunogenic cell death83
Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain82
Multilayered hydrogel scaffold construct with native tissue matched elastic modulus: A regenerative microenvironment for urethral scar-free healing82
A pancreatic cancer organoid incorporating macrophages reveals the correlation between the diversity of tumor-associated macrophages and cancer cell survival82
Polyphenol-assisted facile assembly of bioactive nanoparticles for targeted therapy of heart diseases82
Orchestrated metal-coordinated carrier-free celastrol hydrogel intensifies T cell activation and regulates response to immune checkpoint blockade for synergistic chemo-immunotherapy82
A versatile photothermal vaccine based on acid-responsive glyco-nanoplatform for synergistic therapy of cancer82
Bovine serum albumin framed activatable NIR AIE photosensitizer for targeted tumor therapy81
Corneal stromal structure replicating humanized hydrogel patch for sutureless repair of deep anterior-corneal defect81
Systemic delivery of mRNA and DNA to the lung using polymer-lipid nanoparticles81
m7G-modified mt-tRF3b-LeuTAA regulates mitophagy and metabolic reprogramming via SUMOylation of SIRT3 in chondrocytes81
The use of a multi-metric readout screen to identify EHMT2/G9a-inhibition as a modulator of cancer-associated fibroblast activation state81
Conversion of albumin into a BODIPY-like photosensitizer by a flick reaction, tumor accumulation and photodynamic therapy81
Multifaceted roles of a bioengineered nanoreactor in repressing radiation-induced lung injury80
Shell-mediated phagocytosis to reshape viral-vectored vaccine-induced immunity80
A NIR-II emissive sonosensitized biotuner for pyroptosis-enhanced sonodynamic therapy of hypoxic tumors80
A versatile gas-generator promoting drug release and oxygen replenishment for amplifying photodynamic-chemotherapy synergetic anti-tumor effects79
Development of a magnetically aligned regenerative tissue-engineered electronic nerve interface for peripheral nerve applications79
Nanoparticle shell structural cues drive in vitro transport properties, tissue distribution and brain accessibility in zebrafish78
Polymeric nanomedicine for overcoming resistance mechanisms in hedgehog and Myc-amplified medulloblastoma78
Targeted sonodynamic therapy induces tumor cell quasi-immunogenic ferroptosis and macrophage immunostimulatory autophagy in glioblastoma77
SHMT1 siRNA-Loaded hyperosmotic nanochains for blood-brain/tumor barrier post-transmigration therapy77
Targeted in situ self-assembly augments peptide drug conjugate cell-entry efficiency77
Triple cascade nanocatalyst with laser-activatable O2 supply and photothermal enhancement for effective catalytic therapy against hypoxic tumor77
Construction of functional biliary epithelial branched networks with predefined geometry using digital light stereolithography76
Polymeric PD-L1 blockade nanoparticles for cancer photothermal-immunotherapy76
Repair of peripheral nerve injuries using a prevascularized cell-based tissue-engineered nerve conduit76
Injectable recombinant block polymer gel for sustained delivery of therapeutic protein in post traumatic osteoarthritis75
Advances in controlled drug delivery to the sinonasal mucosa75
Acidity-targeting transition-aided universal chimeric antigen receptor T-cell (ATT-CAR-T) therapy for the treatment of solid tumors74
An in vitro chondro-osteo-vascular triphasic model of the osteochondral complex74
Engineering supramolecular dynamics of self-assembly and turnover of oncogenic microRNAs to drive their synergistic destruction in tumor models74
Graphene oxide prevents lateral amygdala dysfunctional synaptic plasticity and reverts long lasting anxiety behavior in rats74
A clinically relevant formulation for direct administration of nerve specific fluorophores to mitigate iatrogenic nerve injury74
Bone targeting nanocarrier-assisted delivery of adenosine to combat osteoporotic bone loss74
Heterospheroid formation improves therapeutic efficacy of mesenchymal stem cells in murine colitis through immunomodulation and epithelial regeneration74
NAD(P)H-triggered probe for dual-modal imaging during energy metabolism and novel strategy of enhanced photothermal therapy in tumor74
Nitroreductase-responsive nanoparticles for in situ fluorescence imaging and synergistic antibacterial therapy of bacterial keratitis73
PEGylation of poly(amine-co-ester) polyplexes for tunable gene delivery73
Bioactive nanocomposite hydrogel enhances postoperative immunotherapy and bone reconstruction for osteosarcoma treatment73
Solubilized ubiquinol for preserving corneal function72
An ultra-long-acting L-asparaginase synergizes with an immune checkpoint inhibitor in starvation-immunotherapy of metastatic solid tumors72
Epidermal secretion-purified biosensing patch with hydrogel sebum filtering membrane and unidirectional flow microfluidic channels72
Extended-release of therapeutic microRNA via a host-guest supramolecular hydrogel to locally alleviate renal interstitial fibrosis71
A dendritic cell-recruiting, antimicrobial blood clot hydrogel for melanoma recurrence prevention and infected wound management71
Macrophage corpses for immunoregulation and targeted drug delivery in treatment of collagen-induced arthritis mice71
Engineering hirudin encapsulation in pH-responsive antioxidant nanoparticles for therapeutic efficacy in ischemic stroke model mice71
Dual-step irradiation strategy to sequentially destroy singlet oxygen-responsive polymeric micelles and boost photodynamic cancer therapy71
Engineered endothelium model enables recapitulation of vascular function and early atherosclerosis development70
Novel platinum therapeutics induce rapid cancer cell death through triggering intracellular ROS storm70
Corrigendum to “PEGylated fullerene/iron oxide nanocomposites for photodynamic therapy, targeted drug delivery and MR imaging” [Biomaterials 34 (2013) 9666–9677/ pubmed: 24034498]69
Supramolecular organic frameworks improve the safety of clinically used porphyrin photodynamic agents and maintain their antitumor efficacy69
Nano-metal–organic-frameworks for treating H2O2-Secreting bacteria alleviate pulmonary injury and prevent systemic sepsis69
Corrigendum to “Co-delivery of HIF1α siRNA and gemcitabine via biocompatible lipid-polymer hybrid nanoparticles for effective treatment of pancreatic cancer” [Biomaterials 46 (2015) 13–25]69
Biofunctionalized graphene oxide nanosheet for amplifying antitumor therapy: Multimodal high drug encapsulation, prolonged hyperthermal window, and deep-site burst drug release69
Corrigendum to “Cerium oxide nanoparticles with antioxidative neurorestoration for ischemic stroke” [Biomaterials 291(2022) 121904]69
Efficient drug supply in stem cell cytosol via pore-forming saponin nanoparticles promotes in vivo osteogenesis and bone regeneration69
Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma69
Corrigendum to ‘Engineered cell-laden human protein-based elastomer’ [34(2013), 5496–5505]68
Exposure to nanoplastics impairs collective contractility of neonatal cardiomyocytes under electrical synchronization68
Retraction notice to “Synergistic anticancer effect of RNAi and photothermal therapy mediated by functionalized single-walled carbon nanotubes” [Biomaterials 34/1 (2013) 14383]68
Corrigendum to “Celastrol nanoemulsion induces immunogenicity and downregulates PD-L1 to boost abscopal effect in melanoma therapy” [Biomaterials 269 (2021) 120604]68
Mild magnetic hyperthermia-activated immuno-responses for primary bladder cancer therapy68
Corrigendum to “MR and PET-CT monitoring of tissue-engineered vascular grafts in the ovine carotid artery” [Biomaterials 216 (2019) 119228]68
Corrigendum to “Sensitivity to antitubulin chemotherapeutics is potentiated by a photoactivable nanoliposome” [Biomaterials 141 (2017) 50–62]68
Converse modulation of Wnt/β-catenin signaling during expansion and differentiation phases of Infrapatellar fat pad-derived MSCs for improved engineering of hyaline cartilage67
In situ customized apolipoprotein B48-enriched protein corona enhances oral gene delivery of chitosan-based nanoparticles67
A bilirubin-derived nanomedicine attenuates the pathological cascade of pulmonary fibrosis67
Glycopeptide-nanotransforrs eyedrops with enhanced permeability and retention for preventing fundus neovascularization66
Nanocodelivery of an NIR photothermal agent and an acid-responsive TLR7 agonist prodrug to enhance cancer photothermal immunotherapy and the abscopal effect66
Antibiotics armed neutrophils as a potential therapy for brain fungal infection caused by chemotherapy-induced neutropenia66
Macrophage-derived biomimetic nanoparticles enhanced SDT combined with immunotherapy inhibited tumor growth and metastasis66
MnO2@CeOx-GAMP radiosensitizer with oxygen vacancies depended mimicking enzyme-like activities for radiosensitization-mediated STING pathway activation66
Nervous tract-bioinspired multi-nanoyarn model system regulating neural differentiation and its transcriptional architecture at single-cell resolution66
Gold nanocluster with AIE: A novel photodynamic antibacterial and deodorant molecule66
A carbonic anhydrase-targeted NIR-II fluorescent cisplatin theranostic nanoparticle for combined therapy of pancreatic tumors66
Delayed neutrophil recruitment allows nascent Staphylococcus aureus biofilm formation and immune evasion65
Endogenous CO imaging in bacterial pneumonia with a NIR fluorescent probe65
Engineering mannosylated pickering emulsions for the targeted delivery of multicomponent vaccines65
Electrospun composite-coated endotracheal tubes with controlled siRNA and drug delivery to lubricate and minimize upper airway injury65
Exosome-decorated bio-heterojunctions reduce heat and ROS transfer distance for boosted antibacterial and tumor therapy65
Infection microenvironment-activated nanoparticles for NIR-II photoacoustic imaging-guided photothermal/chemodynamic synergistic anti-infective therapy65
Ultrasound-enhanced nano catalyst with ferroptosis-apoptosis combined anticancer strategy for metastatic uveal melanoma64
Metformin-containing hydrogel scaffold to augment CAR-T therapy against post-surgical solid tumors64
Enhanced manipulation of tumor microenvironments by nanomotor for synergistic therapy of malignant tumor63
Nanoparticulate DNA scavenger loading methotrexate targets articular inflammation to enhance rheumatoid arthritis treatment63
MoS2 nanoflower-mediated enhanced intratumoral penetration and piezoelectric catalytic therapy63
Nanobody modified high-performance AIE photosensitizer nanoparticles for precise photodynamic oral cancer therapy of patient-derived tumor xenograft63
Two-dimensional nanomaterials-added dynamism in 3D printing and bioprinting of biomedical platforms: Unique opportunities and challenges62
Engineered nanomaterials for synergistic photo-immunotherapy62
Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma62
Future foods: Design, fabrication and production through microfluidics62
Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption62
Gel@CAT-L Hydrogel Mediates Mitochondrial Unfolded Protein Response to Regulate Reactive Oxygen Species and Mitochondrial Homeostasis in Osteoarthritis61
Gint4.T-siHDGF chimera-capped mesoporous silica nanoparticles encapsulating temozolomide for synergistic glioblastoma therapy61
Protein ligand and nanotopography separately drive the phenotype of mouse embryonic stem cells61
Aligned human induced pluripotent stem cell-derived cardiac tissue improves contractile properties through promoting unidirectional and synchronous cardiomyocyte contraction61
Mitochondrial ‘Birth-Death’ coordinator: An intelligent hydrogen nanogenerator to enhance intervertebral disc regeneration61
Multifunctional hybrid exosomes enhanced cancer chemo-immunotherapy by activating the STING pathway61
Exosomes from hypoxic urine-derived stem cells facilitate healing of diabetic wound by targeting SERPINE1 through miR-486-5p61
Camouflaging nanoreactor traverse the blood-brain barrier to catalyze redox cascade for synergistic therapy of glioblastoma60
A neoteric antibacterial ceria-silver nanozyme for abiotic surfaces59
Self-reinforced photodynamic immunostimulator to downregulate and block PD-L1 for metastatic breast cancer treatment59
2,2-Bis(hydroxymethyl) propionic acid based cyclic carbonate monomers and their (co)polymers as advanced materials for biomedical applications59
Microgels sense wounds' temperature, pH and glucose59
Engineering aluminum hydroxyphosphate nanoparticles with well-controlled surface property to enhance humoral immune responses as vaccine adjuvants59
Enhanced chemo-photodynamic therapy of an enzyme-responsive prodrug in bladder cancer patient-derived xenograft models59
Locationally activated PRP via an injectable dual-network hydrogel for endometrial regeneration59
Two-phase releasing immune-stimulating composite orchestrates protection against microbial infections59
One-for-all phototheranostics: Single component AIE dots as multi-modality theranostic agent for fluorescence-photoacoustic imaging-guided synergistic cancer therapy59
LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy58
Modular protein engineering-based biomaterials for skeletal tissue engineering58
A generally minimalist strategy of constructing biomineralized high-efficiency personalized nanovaccine combined with immune checkpoint blockade for cancer immunotherapy58
Physiologic flow-conditioning limits vascular dysfunction in engineered human capillaries58
Functional Au nanoparticles for engineering and long-term CT imaging tracking of mesenchymal stem cells in idiopathic pulmonary fibrosis treatment58
Concurrent antibiosis and anti-inflammation against bacterial pneumonia by zinc hexacyanoferrate nanocatalysts58
Control of osteoblast arrangement by osteocyte mechanoresponse through prostaglandin E2 signaling under oscillatory fluid flow stimuli57
Activation, development, and attenuation of modeling- and remodeling-based bone formation in adult rats57
ROS responsive nanoparticles loaded with lipid-specific AIEgen for atherosclerosis-targeted diagnosis and bifunctional therapy56
Orally deliverable sequence-targeted astaxanthin nanoparticles for colitis alleviation56
The intracellular fate and transport mechanism of shape, size and rigidity varied nanocarriers for understanding their oral delivery efficiency56
Engineering mesoporous polydopamine-based potentiate STING pathway activation for advanced anti-biofilm therapy55
Natural biomaterials for sustainable flexible neuromorphic devices55
On-demand targeting nanotheranostics with stimuli-responsive releasing property to improve delivery efficiency to cancer55
Biomimetic nanoreactor for targeted cancer starvation therapy and cascade amplificated chemotherapy55
Cyclic reactions-mediated self-supply of H2O2 and O2 for cooperative chemodynamic/starvation cancer therapy54
An injectable and active hydrogel induces mutually enhanced mild magnetic hyperthermia and ferroptosis54
Remodeling of imbalanced extracellular matrix homeostasis for reversal of pancreatic fibrosis54
A self-cascaded unimolecular prodrug for pH-responsive chemotherapy and tumor-detained photodynamic-immunotherapy of triple-negative breast cancer54
Modifications of Ganoderma lucidum spores into digestive-tissue highly adherent porous carriers with selective affinity to hydrophilic or hydrophobic drugs54
A catechol bioadhesive for rapid hemostasis and healing of traumatic internal organs and major arteries54
An all-in-one adjuvanted therapeutic cancer vaccine targeting dendritic cell cytosol induces long-lived tumor suppression through NLRC4 inflammasome activation54
H2O2-activatable hybrid prodrug nanoassemblies as a pure nanodrug for hepatic ischemia/reperfusion injury54
Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing54
In vivo therapeutic genome editing via CRISPR/Cas9 magnetoplexes for myocardial infarction53
Organic single molecule based nano-platform for NIR-II imaging and chemo-photothermal synergistic treatment of tumor53
“On/off”-switchable crosslinked PTX-nanoformulation with improved precise delivery for NSCLC brain metastases and restrained adverse reaction over nab-PTX53
A novel red-emitting aggregation-induced emission probe for determination of β-glucosidase activity53
Mesenchymal stem cell-based bioengineered constructs enhance vaginal repair in ovariectomized rhesus monkeys53
Conditioned medium of human bone marrow-derived stem cells promotes tendon-bone healing of the rotator cuff in a rat model53
Fibrous aggregates: Amplifying aggregation-induced emission to boost health protection53
Chirality-driven strong thioredoxin reductase inhibition53
OGA activated glycopeptide-based nano-activator to activate PKM2 tetramerization for switching catabolic pathways and sensitizing chemotherapy resistance53
In vitro and in vivo investigation of a zonal microstructured scaffold for osteochondral defect repair53
Near-infrared target enhanced peripheral clearance of amyloid-β in Alzheimer's disease model53
3D-printed oxygen-releasing scaffolds improve bone regeneration in mice52
Exosome camouflaged coordination-assembled Iridium(III) photosensitizers for apoptosis-autophagy-ferroptosis induced combination therapy against melanoma52
RGD peptide modified platinum nanozyme Co-loaded glutathione-responsive prodrug nanoparticles for enhanced chemo-photodynamic bladder cancer therapy52
Facile one-step synthesis of NIR-Responsive siRNA-Inorganic hybrid nanoplatform for imaging-guided photothermal and gene synergistic therapy52
Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia52
CaCO3 nanoparticles incorporated with KAE to enable amplified calcium overload cancer therapy52
Small-diameter vascular graft composing of core-shell structured micro-nanofibers loaded with heparin and VEGF for endothelialization and prevention of neointimal hyperplasia52
Wearable and implantable devices for drug delivery: Applications and challenges52
Aseptic and septic prosthetic joint loosening: Impact of biomaterial wear on immune cell function, inflammation, and infection52
Ruthenium complexes boost NK cell immunotherapy via sensitizing triple-negative breast cancer and shaping immuno-microenvironment52
Smart filtering facepiece respirator with self-adaptive fit and wireless humidity monitoring51
An injectable antibacterial chitosan-based cryogel with high absorbency and rapid shape recovery for noncompressible hemorrhage and wound healing51
Injectable and adhesive MgO2-potentiated hydrogel with sequential tumor synergistic therapy and osteogenesis for challenging postsurgical osteosarcoma treatment51
Hydrogels derived from decellularized liver tissue support the growth and differentiation of cholangiocyte organoids51
Optimized BMSC-derived osteoinductive exosomes immobilized in hierarchical scaffold via lyophilization for bone repair through Bmpr2/Acvr2b competitive receptor-activated Smad pathway51
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