Biomaterials

Article	Citations
Advances in nanomaterials for photodynamic therapy applications: Status and challenges	475
ROS-scavenging hydrogel to promote healing of bacteria infected diabetic wounds	373
Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy	372
Exosome laden oxygen releasing antioxidant and antibacterial cryogel wound dressing OxOBand alleviate diabetic and infectious wound healing	242
Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment	231
Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and Re-polarization	223
Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner	205
Au2Pt-PEG-Ce6 nanoformulation with dual nanozyme activities for synergistic chemodynamic therapy / phototherapy	205
A physicochemical double cross-linked multifunctional hydrogel for dynamic burn wound healing: shape adaptability, injectable self-healing property and enhanced adhesion	186
A novel “hot spring”-mimetic hydrogel with excellent angiogenic properties for chronic wound healing	186
Exosome-mediated delivery of kartogenin for chondrogenesis of synovial fluid-derived mesenchymal stem cells and cartilage regeneration	178
Polydopamine-coated nucleic acid nanogel for siRNA-mediated low-temperature photothermal therapy	177
Promoting the healing of infected diabetic wound by an anti-bacterial and nano-enzyme-containing hydrogel with inflammation-suppressing, ROS-scavenging, oxygen and nitric oxide-generating properties	175
Extracellular vesicles: A bright star of nanomedicine	174
Fenton reaction-independent ferroptosis therapy via glutathione and iron redox couple sequentially triggered lipid peroxide generator	171
Mesenchymal stem cell-derived magnetic extracellular nanovesicles for targeting and treatment of ischemic stroke	171
M1 macrophage exosomes engineered to foster M1 polarization and target the IL-4 receptor inhibit tumor growth by reprogramming tumor-associated macrophages into M1-like macrophages	165
Programming cell pyroptosis with biomimetic nanoparticles for solid tumor immunotherapy	163
4D-bioprinted silk hydrogels for tissue engineering	161
Bioinspired exosome-like therapeutics and delivery nanoplatforms	157
Application of conductive PPy/SF composite scaffold and electrical stimulation for neural tissue engineering	152
PB@PDA@Ag nanosystem for synergistically eradicating MRSA and accelerating diabetic wound healing assisted with laser irradiation	152
Gene-engineered exosomes-thermosensitive liposomes hybrid nanovesicles by the blockade of CD47 signal for combined photothermal therapy and cancer immunotherapy	146
Tumor extravasation and infiltration as barriers of nanomedicine for high efficacy: The current status and transcytosis strategy	145
Light-activatable liposomes for repetitive on-demand drug release and immunopotentiation in hypoxic tumor therapy	145

Rapid printing of bio-inspired 3D tissue constructs for skin regeneration	145
The regulation of cartilage extracellular matrix homeostasis in joint cartilage degeneration and regeneration	144
Microfluidic formulation of nanoparticles for biomedical applications	144
Activatable nanomedicine for overcoming hypoxia-induced resistance to chemotherapy and inhibiting tumor growth by inducing collaborative apoptosis and ferroptosis in solid tumors	142
Enhanced cancer therapy by hypoxia-responsive copper metal-organic frameworks nanosystem	141
Inflammatory tumor microenvironment responsive neutrophil exosomes-based drug delivery system for targeted glioma therapy	138
NIR-II bioimaging of small organic molecule	133
Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice	132
Injectable redox and light responsive MnO2 hybrid hydrogel for simultaneous melanoma therapy and multidrug-resistant bacteria-infected wound healing	132
Injectable Mussel‐Inspired highly adhesive hydrogel with exosomes for endogenous cell recruitment and cartilage defect regeneration	129
Modulation of macrophages by bioactive glass/sodium alginate hydrogel is crucial in skin regeneration enhancement	127
Nanodrug with dual-sensitivity to tumor microenvironment for immuno-sonodynamic anti-cancer therapy	124
Advances and perspectives in carrier-free nanodrugs for cancer chemo-monotherapy and combination therapy	124
Defect modified zinc oxide with augmenting sonodynamic reactive oxygen species generation	124
Bioorthogonal-targeted 1064 nm excitation theranostic nanoplatform for precise NIR-IIa fluorescence imaging guided efficient NIR-II photothermal therapy	121
3D bioprinted neural tissue constructs for spinal cord injury repair	119
Bioinspired stratified electrowritten fiber-reinforced hydrogel constructs with layer-specific induction capacity for functional osteochondral regeneration	116
Gut-on-a-chip: Current progress and future opportunities	115
PRP-chitosan thermoresponsive hydrogel combined with black phosphorus nanosheets as injectable biomaterial for biotherapy and phototherapy treatment of rheumatoid arthritis	114
MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system	110
A versatile nanocomposite based on nanoceria for antibacterial enhancement and protection from aPDT-aggravated inflammation via modulation of macrophage polarization	109
Infection microenvironment-activated nanoparticles for NIR-II photoacoustic imaging-guided photothermal/chemodynamic synergistic anti-infective therapy	109
Regulation of extracellular matrix assembly and structure by hybrid M1/M2 macrophages	108
Optimized BMSC-derived osteoinductive exosomes immobilized in hierarchical scaffold via lyophilization for bone repair through Bmpr2/Acvr2b competitive receptor-activated Smad pathway	108
‘Green’ nanotherapeutics from tea leaves for orally targeted prevention and alleviation of colon diseases	107
Intelligent MoS2–CuO heterostructures with multiplexed imaging and remarkably enhanced antitumor efficacy via synergetic photothermal therapy/ chemodynamic therapy/ immunotherapy	107
A mitochondria-targeting magnetothermogenic nanozyme for magnet-induced synergistic cancer therapy	105
Biomimetic osteogenic peptide with mussel adhesion and osteoimmunomodulatory functions to ameliorate interfacial osseointegration under chronic inflammation	104
Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids	103
NIR-II emissive multifunctional AIEgen with single laser-activated synergistic photodynamic/photothermal therapy of cancers and pathogens	103
Exosomes-loaded thermosensitive hydrogels for corneal epithelium and stroma regeneration	102
Hyaluronic acid and chondroitin sulfate (meth)acrylate-based hydrogels for tissue engineering: Synthesis, characteristics and pre-clinical evaluation	102
Emerging photodynamic nanotherapeutics for inducing immunogenic cell death and potentiating cancer immunotherapy	101
MOF-encapsulated nanozyme enhanced siRNA combo: Control neural stem cell differentiation and ameliorate cognitive impairments in Alzheimer's disease model	101
Cryogel/hydrogel biomaterials and acupuncture combined to promote diabetic skin wound healing through immunomodulation	100
Biomimetic CoO@AuPt nanozyme responsive to multiple tumor microenvironmental clues for augmenting chemodynamic therapy	99
Infection microenvironment-related antibacterial nanotherapeutic strategies	99
An APN-activated NIR photosensitizer for cancer photodynamic therapy and fluorescence imaging	98
Targeting nanoparticles for diagnosis and therapy of bone tumors: Opportunities and challenges	98
Phagocyte-membrane-coated and laser-responsive nanoparticles control primary and metastatic cancer by inducing anti-tumor immunity	98
Functionalized 3D-printed silk-hydroxyapatite scaffolds for enhanced bone regeneration with innervation and vascularization	97
Biodegradable Poly(γ-glutamic acid)@glucose oxidase@carbon dot nanoparticles for simultaneous multimodal imaging and synergetic cancer therapy	97
Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier & targeting ligand	96
How microbes read the map: Effects of implant topography on bacterial adhesion and biofilm formation	96
Fabrication of polyphenol-incorporated anti-inflammatory hydrogel via high-affinity enzymatic crosslinking for wet tissue adhesion	95
Free radicals for cancer theranostics	94
Rod-based urchin-like hollow microspheres of Bi2S3: Facile synthesis, photo-controlled drug release for photoacoustic imaging and chemo-photothermal therapy of tumor ablation	94
The protein corona hampers the transcytosis of transferrin-modified nanoparticles through blood–brain barrier and attenuates their targeting ability to brain tumor	93
Site-specific MOF-based immunotherapeutic nanoplatforms via synergistic tumor cells-targeted treatment and dendritic cells-targeted immunomodulation	93
Resolution of inflammation in bone regeneration: From understandings to therapeutic applications	93

Inhibition of neutrophil elastase prevents neutrophil extracellular trap formation and rescues mice from endotoxic shock	93
Polymeric nanoparticle vaccines to combat emerging and pandemic threats	93
Near-infrared-II activated inorganic photothermal nanomedicines	92
The effect of a nanofiber-hydrogel composite on neural tissue repair and regeneration in the contused spinal cord	91
Long-acting nanoparticulate DNase-1 for effective suppression of SARS-CoV-2-mediated neutrophil activities and cytokine storm	90
Iridium/ruthenium nanozyme reactors with cascade catalytic ability for synergistic oxidation therapy and starvation therapy in the treatment of breast cancer	90
Microenvironment-driven sequential ferroptosis, photodynamic therapy, and chemotherapy for targeted breast cancer therapy by a cancer-cell-membrane-coated nanoscale metal-organic framework	90
Near-infrared light II - assisted rapid biofilm elimination platform for bone implants at mild temperature	89
Photothermal conversion-coordinated Fenton-like and photocatalytic reactions of Cu2-xSe-Au Janus nanoparticles for tri-combination antitumor therapy	87
Tough magnesium phosphate-based 3D-printed implants induce bone regeneration in an equine defect model	86
A NIR light triggered disintegratable nanoplatform for enhanced penetration and chemotherapy in deep tumor tissues	86
An exosome-like programmable-bioactivating paclitaxel prodrug nanoplatform for enhanced breast cancer metastasis inhibition	86
AIEgens for microbial detection and antimicrobial therapy	86
Heparanase-driven sequential released nanoparticles for ferroptosis and tumor microenvironment modulations synergism in breast cancer therapy	86
Aligned microfiber-induced macrophage polarization to guide schwann-cell-enabled peripheral nerve regeneration	86
Core-shell structured upconversion nanocrystal-dendrimer composite as a carrier for mitochondria targeting and catalase enhanced anti-cancer photodynamic therapy	85
Immunopolarization-regulated 3D printed-electrospun fibrous scaffolds for bone regeneration	85
Tunable bioactivity and mechanics of collagen-based tissue engineering constructs: A comparison of EDC-NHS, genipin and TG2 crosslinkers	84
Synthetic macromolecules as therapeutics that overcome resistance in cancer and microbial infection	84
A micro/nano-biomimetic coating on titanium orchestrates osteo/angio-genesis and osteoimmunomodulation for advanced osseointegration	84
Versatile hollow COF nanospheres via manipulating transferrin corona for precise glioma-targeted drug delivery	83
Phenolic immunogenic cell death nanoinducer for sensitizing tumor to PD-1 checkpoint blockade immunotherapy	83
MSC spheroids-loaded collagen hydrogels simultaneously promote neuronal differentiation and suppress inflammatory reaction through PI3K-Akt signaling pathway	83
3D anisotropic photocatalytic architectures as bioactive nerve guidance conduits for peripheral neural regeneration	83
A redox-triggered C-centered free radicals nanogenerator for self-enhanced magnetic resonance imaging and chemodynamic therapy	82
Cancer cell membrane camouflaged iridium complexes functionalized black-titanium nanoparticles for hierarchical-targeted synergistic NIR-II photothermal and sonodynamic therapy	82
Skin-inspired gelatin-based flexible bio-electronic hydrogel for wound healing promotion and motion sensing	82
Fucoidan-based, tumor-activated nanoplatform for overcoming hypoxia and enhancing photodynamic therapy and antitumor immunity	82
Trends of microneedle technology in the scientific literature, patents, clinical trials and internet activity	81
Virus-like nanoparticle as a co-delivery system to enhance efficacy of CRISPR/Cas9-based cancer immunotherapy	81
Chitosan hydrogel/3D-printed poly(ε‐caprolactone) hybrid scaffold containing synovial mesenchymal stem cells for cartilage regeneration based on tetrahedral framework nucleic acid recruitment	81
Recent development of metal-organic framework nanocomposites for biomedical applications	81
Injectable dual-scale mesoporous silica cancer vaccine enabling efficient delivery of antigen/adjuvant-loaded nanoparticles to dendritic cells recruited in local macroporous scaffold	80
A tunable self-healing ionic hydrogel with microscopic homogeneous conductivity as a cardiac patch for myocardial infarction repair	80
3D cell-printing of biocompatible and functional meniscus constructs using meniscus‐derived bioink	80
Cancer-activated doxorubicin prodrug nanoparticles induce preferential immune response with minimal doxorubicin-related toxicity	80
3D-bioprinted BMSC-laden biomimetic multiphasic scaffolds for efficient repair of osteochondral defects in an osteoarthritic rat model	80
Tumor microenvironment responsive hollow mesoporous Co9S8@MnO2-ICG/DOX intelligent nanoplatform for synergistically enhanced tumor multimodal therapy	79
Small molecules combined with collagen hydrogel direct neurogenesis and migration of neural stem cells after spinal cord injury	79
Understanding the role of tissue-specific decellularized spinal cord matrix hydrogel for neural stem/progenitor cell microenvironment reconstruction and spinal cord injury	79
Ru@CeO2 yolk shell nanozymes: Oxygen supply in situ enhanced dual chemotherapy combined with photothermal therapy for orthotopic/subcutaneous colorectal cancer	79
Designer exosomes enabling tumor targeted efficient chemo/gene/photothermal therapy	78
Sequential growth factor releasing double cryogel system for enhanced bone regeneration	78
Renal clearable Hafnium-doped carbon dots for CT/Fluorescence imaging of orthotopic liver cancer	78
Harnessing carbon monoxide-releasing platforms for cancer therapy	78
Engineering oxygen-deficient ZrO2-x nanoplatform as therapy-activated “immunogenic cell death (ICD)” inducer to synergize photothermal-augmented sonodynamic tumor elimination in NIR-II biological wind	78
Cell migration regulated by RGD nanospacing and enhanced under moderate cell adhesion on biomaterials	77
Nanobiomaterial-based vaccination immunotherapy of cancer	77
Multi-enzyme mimetic ultrasmall iridium nanozymes as reactive oxygen/nitrogen species scavengers for acute kidney injury management	76
High-quality milk exosomes as oral drug delivery system	76
Nanosponges of circulating tumor-derived exosomes for breast cancer metastasis inhibition	76
In Situ implantable, post-trauma microenvironment-responsive, ROS Depletion Hydrogels for the treatment of Traumatic brain injury	76
D-arginine-loaded metal-organic frameworks nanoparticles sensitize osteosarcoma to radiotherapy	76
Cartilage matrix-inspired biomimetic superlubricated nanospheres for treatment of osteoarthritis	75
Nanoengineered shear-thinning and bioprintable hydrogel as a versatile platform for biomedical applications	75
Nitric oxide-induced stromal depletion for improved nanoparticle penetration in pancreatic cancer treatment	75
Photo-activated chemo-immunotherapy for metastatic cancer using a synergistic graphene nanosystem	75
Neuronal mitochondria-targeted micelles relieving oxidative stress for delayed progression of Alzheimer's disease	75
Quantitative analysis of interactive behavior of mitochondria and lysosomes using structured illumination microscopy	75
Covalent grafting of hyperbranched poly-L-lysine on Ti-based implants achieves dual functions of antibacteria and promoted osteointegration in vivo	75
Noninvasively immunogenic sonodynamic therapy with manganese protoporphyrin liposomes against triple-negative breast cancer	75
Cascade of reactive oxygen species generation by polyprodrug for combinational photodynamic therapy	74
Intelligent micro-/nanorobots as drug and cell carrier devices for biomedical therapeutic advancement: Promising development opportunities and translational challenges	74
Biomimetic glycopeptide hydrogel coated PCL/nHA scaffold for enhanced cranial bone regeneration via macrophage M2 polarization-induced osteo-immunomodulation	74
Dually functional hollow ceria nanoparticle platform for intraocular drug delivery: A push beyond the limits of static and dynamic ocular barriers toward glaucoma therapy	74
In Vivo-assembled phthalocyanine/albumin supramolecular complexes combined with a hypoxia-activated prodrug for enhanced photodynamic immunotherapy of cancer	74
Clodronate-loaded liposomal and fibroblast-derived exosomal hybrid system for enhanced drug delivery to pulmonary fibrosis	74
Oxaliplatin-/NLG919 prodrugs-constructed liposomes for effective chemo-immunotherapy of colorectal cancer	74
Precise magnetic resonance imaging-guided sonodynamic therapy for drug-resistant bacterial deep infection	74
Tumor microenvironment-responsive prodrug nanoplatform via co-self-assembly of photothermal agent and IDO inhibitor for enhanced tumor penetration and cancer immunotherapy	74
A DAMP-scavenging, IL-10-releasing hydrogel promotes neural regeneration and motor function recovery after spinal cord injury	73
Monocyte mimics improve mesenchymal stem cell-derived extracellular vesicle homing in a mouse MI/RI model	73
Multifunctional liquid metal-based nanoparticles with glycolysis and mitochondrial metabolism inhibition for tumor photothermal therapy	72
Red-light-triggered self-destructive mesoporous silica nanoparticles for cascade-amplifying chemo-photodynamic therapy favoring antitumor immune responses	72
Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo	72
Tumor-derived exosomes co-delivering aggregation-induced emission luminogens and proton pump inhibitors for tumor glutamine starvation therapy and enhanced type-I photodynamic therapy	72
Rationally designed rapamycin-encapsulated ZIF-8 nanosystem for overcoming chemotherapy resistance	72
Targeted camptothecin delivery via silicon nanoparticles reduces breast cancer metastasis	72
Single and multi-functional coating strategies for enhancing the biocompatibility and tissue integration of blood-contacting medical implants	72
Porous Pt nanoparticles loaded with doxorubicin to enable synergistic Chemo-/Electrodynamic Therapy	71

Wnt signaling modulates macrophage polarization and is regulated by biomaterial surface properties	71
Mononuclear phagocyte system blockade using extracellular vesicles modified with CD47 on membrane surface for myocardial infarction reperfusion injury treatment	71
Dragonfly-shaped near-infrared AIEgen with optimal fluorescence brightness for precise image-guided cancer surgery	71
Biocompatible Fe-Hematoporphyrin coordination nanoplatforms with efficient sonodynamic-chemo effects on deep-seated tumors	71
Injectable ferrimagnetic silk fibroin hydrogel for magnetic hyperthermia ablation of deep tumor	70
Activatable NIR-II photoacoustic imaging and photochemical synergistic therapy of MRSA infections using miniature Au/Ag nanorods	70
Direct 3D bioprinting of cardiac micro-tissues mimicking native myocardium	69
Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery	69
High-strength, porous additively manufactured implants with optimized mechanical osseointegration	69
Intelligently thermoresponsive flower-like hollow nano-ruthenium system for sustained release of nerve growth factor to inhibit hyperphosphorylation of tau and neuronal damage for the treatment of Alz	69
Bioadhesive injectable hydrogel with phenolic carbon quantum dot supported Pd single atom nanozymes as a localized immunomodulation niche for cancer catalytic immunotherapy	69
Near infrared light-triggered metal ion and photodynamic therapy based on AgNPs/porphyrinic MOFs for tumors and pathogens elimination	69
Cationization to boost both type I and type II ROS generation for photodynamic therapy	68
Advances in 3D bioprinting of tissues/organs for regenerative medicine and in-vitro models	68
Flexible patch with printable and antibacterial conductive hydrogel electrodes for accelerated wound healing	68
Three-dimensional bio-printing of primary human hepatocellular carcinoma for personalized medicine	68
Injectable hydrogel for postoperative synergistic photothermal-chemodynamic tumor and anti-infection therapy	68
Enhancing antibody-dependent cellular phagocytosis by Re-education of tumor-associated macrophages with resiquimod-encapsulated liposomes	67
Tumor microenvironment triple-responsive nanoparticles enable enhanced tumor penetration and synergetic chemo-photodynamic therapy	67
Transdermal colorimetric patch for hyperglycemia sensing in diabetic mice	67
Fucoidan functionalization on poly(vinyl alcohol) hydrogels for improved endothelialization and hemocompatibility	67
Dual enzyme-mimic nanozyme based on single-atom construction strategy for photothermal-augmented nanocatalytic therapy in the second near-infrared biowindow	67
Cancer immunogenic cell death via photo-pyroptosis with light-sensitive Indoleamine 2,3-dioxygenase inhibitor conjugate	67
Nanofibrous composite aerogel with multi-bioactive and fluid gating characteristics for promoting diabetic wound healing	67
Corn-like Au/Ag nanorod-mediated NIR-II photothermal/photodynamic therapy potentiates immune checkpoint antibody efficacy by reprogramming the cold tumor microenvironment	67
Progress and perspective of microneedle system for anti-cancer drug delivery	67
Bio-orthogonally crosslinked hyaluronate-collagen hydrogel for suture-free corneal defect repair	67
Brain-targeted delivery shuttled by black phosphorus nanostructure to treat Parkinson's disease	66
Aseptic and septic prosthetic joint loosening: Impact of biomaterial wear on immune cell function, inflammation, and infection	66
3D-printable plant protein-enriched scaffolds for cultivated meat development	66
Designing immunogenic nanotherapeutics for photothermal-triggered immunotherapy involving reprogramming immunosuppression and activating systemic antitumor responses	66
3D culture of HepaRG cells in GelMa and its application to bioprinting of a multicellular hepatic model	66
Light-controlled oxygen production and collection for sustainable photodynamic therapy in tumor hypoxia	65
Metformin facilitates mesenchymal stem cell-derived extracellular nanovesicles release and optimizes therapeutic efficacy in intervertebral disc degeneration	65
Lymph node-targeted immune-activation mediated by imiquimod-loaded mesoporous polydopamine based-nanocarriers	65
Digital CRISPR-based method for the rapid detection and absolute quantification of nucleic acids	64
Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors	64
Highly dispersed nano-enzyme triggered intracellular catalytic reaction toward cancer specific therapy	64
A novel hydrogel-based treatment for complete transection spinal cord injury repair is driven by microglia/macrophages repopulation	64
Wet-adhesive, haemostatic and antimicrobial bilayered composite nanosheets for sealing and healing soft-tissue bleeding wounds	64
A viscoelastic PEGylated poly(glycerol sebacate)-based bilayer scaffold for cartilage regeneration in full-thickness osteochondral defect	63
Biomimetic nanoreactor for targeted cancer starvation therapy and cascade amplificated chemotherapy	63
Dual actions of osteoclastic-inhibition and osteogenic-stimulation through strontium-releasing bioactive nanoscale cement imply biomaterial-enabled osteoporosis therapy	63
Cyclic reactions-mediated self-supply of H2O2 and O2 for cooperative chemodynamic/starvation cancer therapy	63
NIR-II fluorescence imaging guided tumor-specific NIR-II photothermal therapy enhanced by starvation mediated thermal sensitization strategy	63
Injectable hydrogels with high drug loading through B–N coordination and ROS-triggered drug release for efficient treatment of chronic periodontitis in diabetic rats	63
Decellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine	63
Injectable immunomodulation-based porous chitosan microspheres/HPCH hydrogel composites as a controlled drug delivery system for osteochondral regeneration	62
Construction and application of therapeutic metal-polyphenol capsule for peripheral artery disease	62
Multifunctional magnesium incorporated scaffolds by 3D-Printing for comprehensive postsurgical management of osteosarcoma	62
Smart transformable nanomedicines for cancer therapy	62
Enhanced chemo-photodynamic therapy of an enzyme-responsive prodrug in bladder cancer patient-derived xenograft models	62
Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling	62
A functional scaffold to promote the migration and neuronal differentiation of neural stem/progenitor cells for spinal cord injury repair	62
Magnesium and vitamin C supplementation attenuates steroid-associated osteonecrosis in a rat model	61
Epigallocatechin gallate mediated sandwich-like coating for mimicking endothelium with sustained therapeutic nitric oxide generation and heparin release	61
Engineering antigen as photosensitiser nanocarrier to facilitate ROS triggered immune cascade for photodynamic immunotherapy	61
Injectable biodegradation-visual self-healing citrate hydrogel with high tissue penetration for microenvironment-responsive degradation and local tumor therapy	61
Chitosan/γ-PGA nanoparticles-based immunotherapy as adjuvant to radiotherapy in breast cancer	61
A multifunctional anti-inflammatory drug that can specifically target activated macrophages, massively deplete intracellular H2O2, and produce large amounts CO for a highly efficient treatment of oste	61
The effect of hypoxia-mimicking responses on improving the regeneration of artificial vascular grafts	60
A low-temperature-printed hierarchical porous sponge-like scaffold that promotes cell-material interaction and modulates paracrine activity of MSCs for vascularized bone regeneration	60
Targeting self-assembly peptide for inhibiting breast tumor progression and metastasis	60
Sequential activation of heterogeneous macrophage phenotypes is essential for biomaterials-induced bone regeneration	60
Photocrosslinkable nanocomposite ink for printing strong, biodegradable and bioactive bone graft	60
Sequential delivery of nanoformulated α-mangostin and triptolide overcomes permeation obstacles and improves therapeutic effects in pancreatic cancer	60
Delivery of manganese carbonyl to the tumor microenvironment using Tumor-Derived exosomes for cancer gas therapy and low dose radiotherapy	60
Active biomaterials for mechanobiology	60
Tunable electroconductive decellularized extracellular matrix hydrogels for engineering human cardiac microphysiological systems	60
Bioinspired membrane provides periosteum-mimetic microenvironment for accelerating vascularized bone regeneration	60
Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis	60
Conditioned medium of human bone marrow-derived stem cells promotes tendon-bone healing of the rotator cuff in a rat model	60
Rational collaborative ablation of bacterial biofilms ignited by physical cavitation and concurrent deep antibiotic release	60
Synergistic tumor immunological strategy by combining tumor nanovaccine with gene-mediated extracellular matrix scavenger	59
Unsaturated polyurethane films grafted with enantiomeric polylysine promotes macrophage polarization to a M2 phenotype through PI3K/Akt1/mTOR axis	59
Nanomedicine progress in thrombolytic therapy	59
Self-assembly of stem cell membrane-camouflaged nanocomplex for microRNA-mediated repair of myocardial infarction injury	59
Nano-herb medicine and PDT induced synergistic immunotherapy for colon cancer treatment	59
Photothermally triggered nitric oxide nanogenerator targeting type IV pili for precise therapy of bacterial infections	58
Graphdiyne nanoradioprotector with efficient free radical scavenging ability for mitigating radiation-induced gastrointestinal tract damage	58
T-cell activation is modulated by the 3D mechanical microenvironment	58
Combating bacterial infection by in situ self-assembly of AIEgen-peptide conjugate	58
Leveraging disulfiram to treat cancer: Mechanisms of action, delivery strategies, and treatment regimens	58
Photodynamic therapy produces enhanced efficacy of antitumor immunotherapy by simultaneously inducing intratumoral release of sorafenib	58
High-purity weight-bearing magnesium screw: Translational application in the healing of femoral neck fracture	57
A tailored extracellular matrix (ECM) - Mimetic coating for cardiovascular stents by stepwise assembly of hyaluronic acid and recombinant human type III collagen	57
Perfluorocarbon loaded fluorinated covalent organic polymers with effective sonosensitization and tumor hypoxia relief enable synergistic sonodynamic-immunotherapy	57
A hypoxia responsive nanoassembly for tumor specific oxygenation and enhanced sonodynamic therapy	57
Conformable polyimide-based μECoGs: Bringing the electrodes closer to the signal source	57
Overcoming the delivery problem for therapeutic genome editing: Current status and perspective of non-viral methods	57
Dissecting the effects of preconditioning with inflammatory cytokines and hypoxia on the angiogenic potential of mesenchymal stromal cell (MSC)-derived soluble proteins and extracellular vesicles (EVs	57
Cancer-specific drug-drug nanoparticles of pro-apoptotic and cathepsin B-cleavable peptide-conjugated doxorubicin for drug-resistant cancer therapy	57
In situ activation of STING pathway with polymeric SN38 for cancer chemoimmunotherapy	56
Systemic delivery of mRNA and DNA to the lung using polymer-lipid nanoparticles	56
Engineered nanomaterials for synergistic photo-immunotherapy	56