International Endodontic Journal

Article	Citations
The global prevalence of apical periodontitis: a systematic review and meta‐analysis	193
PRILE 2021 guidelines for reporting laboratory studies in Endodontology: A consensus‐based development	160
Present status and future directions: Microbiology of endodontic infections	101
Efficacy of direct pulp capping for management of cariously exposed pulps in permanent teeth: a systematic review and meta‐analysis	83
Present status and future directions – irrigants and irrigation methods	74
Present status and future directions—Vital pulp treatment and pulp preservation strategies	69
Current status on minimal access cavity preparations: a critical analysis and a proposal for a universal nomenclature	60
Virtual reality: an effective tool for teaching root canal anatomy to undergraduate dental students – a preliminary study	57
PRIASE 2021 guidelines for reporting animal studies in Endodontology: a consensus‐based development	56
PRILE 2021 guidelines for reporting laboratory studies in Endodontology: explanation and elaboration	50
Endodontic management of traumatized permanent teeth: a comprehensive review	48
Present status and future directions: Hydraulic materials for endodontic use	46
The restoration of root filled teeth: a review of the clinical literature	42
Association between cardiovascular diseases and apical periodontitis: an umbrella review	42
Clinical cell‐based versus cell‐free regenerative endodontics: clarification of concept and term	40
The influence of endodontic access cavity design on the efficacy of canal instrumentation, microbial reduction, root canal filling and fracture resistance in mandibular molars	39
A prospective clinical study investigating the effectiveness of partial pulpotomy after relating preoperative symptoms to a new and established classification of pulpitis	39
Design, metallurgical features, mechanical performance and canal preparation of six reciprocating instruments	37
Integration of telemedicine into the public health response to COVID‐19 must include dentists	37
MTT versus other cell viability assays to evaluate the biocompatibility of root canal filling materials: a systematic review	37
A macroscopic and histological analysis of radiographically well‐defined deep and extremely deep carious lesions: carious lesion characteristics as indicators of the level of bacterial penetration and	36
Chemical composition and bioactivity potential of the new Endosequence BC Sealer formulation HiFlow	36
Role of respirators in controlling the spread of novel coronavirus (COVID‐19) amongst dental healthcare providers: a review	35
Present status and future directions: Surgical endodontics	35
Biological interactions between calcium silicate‐based endodontic biomaterials and periodontal ligament stem cells: A systematic review of in vitro studies	35

Heating stability, physical and chemical analysis of calcium silicate‐based endodontic sealers	34
Present status and future directions: vertical root fractures in root filled teeth	34
Accuracy and efficiency of guided root‐end resection using a dynamic navigation system: a human cadaver study	34
Publication trends in micro‐CT endodontic research: a bibliometric analysis over a 25‐year period	34
Clinical procedures and outcome of surgical extrusion, intentional replantation and tooth autotransplantation – a narrative review	34
Outcomes of primary root canal therapy: An updated systematic review of longitudinal clinical studies published between 2003 and 2020	33
Clinical endodontic management during the COVID‐19 pandemic: a literature review and clinical recommendations	32
Outcome measures to assess the effectiveness of endodontic treatment for pulpitis and apical periodontitis for use in the development of European Society of Endodontology (ESE) S3 level clinical pract	32
Outcome of full pulpotomy in mature permanent molars using 3 calcium silicate‐based materials: A parallel, double blind, randomized controlled trial	32
Present status and future directions – Guided endodontics	31
Influence of minimally invasive endodontic access cavities on root canal shaping and filling ability, pulp chamber cleaning and fracture resistance of extracted human mandibular incisors	30
Scientometric analysis of vital pulp therapy studies	30
A laboratory study of the impact of ultraconservative access cavities and minimal root canal tapers on the ability to shape canals in extracted mandibular molars and their fracture resistance	30
The Buffalo study: Outcome and associated predictors in endodontic microsurgery‐ a cohort study	29
Present status and future directions: Canal shaping	29
Outcome measures to assess the effectiveness of endodontic treatment for pulpitis and apical periodontitis for use in the development of European Society of Endodontology S3‐level clinical practice gu	29
Rapid detection of SARS‐CoV‐2 in saliva: can an endodontist take the lead in point‐of‐care COVID‐19 testing?	28
European Society of Endodontology position statement: Surgical extrusion, intentional replantation and tooth autotransplantation	28
Present status and future directions – Minimal endodontic access cavities	27
Application of a new system for classifying root and canal anatomy in studies involving micro‐computed tomography and cone beam computed tomography: Explanation and elaboration	27
Chemical and mechanical influence of root canal irrigation on biofilm removal from lateral morphological features of simulated root canals, dentine discs and dentinal tubules	27
Factors that affect the outcomes of root canal treatment and retreatment—A reframing of the principles	26
European Society of Endodontology position statement: endodontic management of traumatized permanent teeth	26
A critical analysis of research methods and experimental models to study irrigants and irrigation systems	26
Present status and future directions: Root resorption	26
Cytocompatibility and bioactive potential of AH Plus Bioceramic Sealer: An in vitro study	26
European Society of Endodontology position statement: The restoration of root filled teeth	26
A critical analysis of research methods and experimental models to study the root canal microbiome	26
Protective device to reduce aerosol dispersion in dental clinics during the COVID‐19 pandemic	26
Review of guidance for the selection of regenerative endodontics, apexogenesis, apexification, pulpotomy, and other endodontic treatments for immature permanent teeth	25
Reduced bone resorption and inflammation in apical periodontitis evoked by dietary supplementation with probiotics in rats	25
A critical evaluation of the material properties and clinical suitability of in‐house printed and commercial tooth replicas for endodontic training	25
The association between apical periodontitis and adverse pregnancy outcomes: a systematic review	24
Dynamic navigation: a laboratory study on the accuracy and potential use of guided root canal treatment	24
A laboratory evaluation of cell viability, radiopacity and tooth discoloration induced by regenerative endodontic materials	24
Does tobacco smoking predispose to apical periodontitis and endodontic treatment need? A systematic review and meta‐analysis	24
Dental nerves: a neglected mediator of pulpitis	24
A critical analysis of research methods and experimental models to study dentinal microcracks	23
Clinical decision‐making and importance of the AAE/AAOMR position statement for CBCT examination in endodontic cases	23
A critical analysis of research methods and experimental models to study pulpitis	23
Prevalence of root canal treatment worldwide: A systematic review and meta‐analysis	23
Present status and future directions of intracanal medicaments	23
Present status and future directions: Surgical extrusion, intentional replantation and tooth autotransplantation	23
MicroRNA‐223 negatively regulates LPS‐induced inflammatory responses by targeting NLRP3 in human dental pulp fibroblasts	23
Diabetes mellitus and the healing of periapical lesions in root filled teeth: a systematic review and meta‐analysis	22
Influence of access cavity design and use of operating microscope and ultrasonic troughing to detect middle mesial canals in extracted mandibular first molars	22
Effects of concentration of sodium hypochlorite as an endodontic irrigant on the mechanical and structural properties of root dentine: A laboratory study	22
Biofilm removal from a simulated isthmus and lateral canal during syringe irrigation at various flow rates: a combined experimental and Computational Fluid Dynamics approach	22
Factors that influence the outcome of pulpotomy in permanent teeth	22
A critical analysis of laboratory and clinical research methods to study root and canal anatomy	22

Treatment of pulpal and apical disease: The European Society of Endodontology (ESE) S3‐level clinical practice guideline	22
Association between concentration of active MMP‐9 in pulpal blood and pulpotomy outcome in permanent mature teeth with irreversible pulpitis – a preliminary study	22
The effect of two calcium silicate‐based and one epoxy resin‐based root canal sealer on postoperative pain: a randomized controlled trial	22
The impact of minimally invasive root canal preparation strategies on the ability to shape root canals of mandibular molars	21
The management of deep carious lesions and the exposed pulp amongst members of two European endodontic societies: a questionnaire‐based study	21
Five decades of the International Endodontic Journal: Bibliometric overview 1967–2020	21
A clinical approach strategy for the diagnosis, treatment and evaluation of external cervical resorption	21
Identification and validation of novel biomarkers and therapeutics for pulpitis using connectivity mapping	21
Eggshell derived nano‐hydroxyapatite incorporated carboxymethyl chitosan scaffold for dentine regeneration: A laboratory investigation	21
PRIRATE 2020 guidelines for reporting randomized trials in Endodontics: explanation and elaboration	21
A critical analysis of research methods and experimental models to study biocompatibility of endodontic materials	20
Antibacterial activity, cytocompatibility and effect of Bio‐C Temp bioceramic intracanal medicament on osteoblast biology	20
Inflammatory biomarkers in dentinal fluid as an approach to molecular diagnostics in pulpitis	20
Abstracts of published randomized controlled trials in Endodontics: reporting quality and spin	20
A laboratory study to test the responses of human dental pulp stem cells to extracts from three dental pulp capping biomaterials	19
Calcium hydroxide‐loaded PLGA biodegradable nanoparticles as an intracanal medicament	19
Potential application of immunotherapy for modulation of pulp inflammation: opportunities for vital pulp treatment	19
PRICE 2020 guidelines for reporting case reports in Endodontics: explanation and elaboration	19
Investigation of microbial profile, levels of endotoxin and lipoteichoic acid in teeth with symptomatic irreversible pulpitis: a clinical study	19
Relationship between apical periodontitis and atherosclerosis in rats: lipid profile and histological study	19
A critical analysis of research methods and experimental models to study the physical properties of NiTi instruments and their fracture characteristics	18
Comparison of design, metallurgy, mechanical performance and shaping ability of replica‐like and counterfeit instruments of the ProTaper Next system	18
Endodontic pulp revitalization in traumatized necrotic immature permanent incisors: Early failures and long‐term outcomes—A longitudinal cohort study	18
Investigating the vascularization capacity of a decellularized dental pulp matrix seeded with human dental pulp stem cells: in vitro and preliminary in vivo evaluations	18
Comparative evaluation of complete and partial pulpotomy in mature permanent teeth with symptomatic irreversible pulpitis: A randomized clinical trial	18
Present status and future directions: Removal of fractured instruments	18
The Endodontic Complexity Assessment Tool (E‐CAT): A digital form for assessing root canal treatment case difficulty	18
Postoperative pain after ultrasonically and laser‐activated irrigation during root canal treatment: a randomized clinical trial	18
To test or not to test? An opportunity to restart dentistry sustainably in the ‘COVID‐19 era’	18
A prospective study on the effect of coronal tooth structure loss on the 4‐year clinical survival of root canal retreated teeth and retrospective validation of the Dental Practicality Index	18
Do orthodontic tooth movements induce pulp necrosis? A systematic review	17
Impact of systemic health on treatment outcomes in endodontics	17
Potential relationship between clinical symptoms and the root canal microbiomes of root filled teeth based on the next‐generation sequencing	17
Evaluation of undergraduate Endodontic teaching in dental schools within Spain	17
Influence of ultraconservative access cavities on instrumentation efficacy with XP‐endo Shaper and Reciproc, filling ability and load capacity of mandibular molars subjected to thermomechanical cyclin	17
Present status and future directions: The restoration of root filled teeth	17
An investigation into security, self‐confidence and gender differences related to undergraduate education in Endodontics	17
Effectiveness of root canal filling materials and techniques for treatment of apical periodontitis: A systematic review	17
A critical appraisal of research methods and experimental models for studies on root canal preparation	17
The impact of apical periodontitis, non‐surgical root canal retreatment and periapical surgery on serum inflammatory biomarkers	17
Impact of different regenerative techniques and materials on the healing outcome of endodontic surgery: a systematic review and meta‐analysis	16
Outcome of partial and full pulpotomy in cariously exposed mature molars with symptoms indicative of irreversible pulpitis: A randomized controlled trial	16
The development of European Society of Endodontology S3‐level guidelines for the treatment of pulpal and apical disease	16
A critical analysis of research methods and experimental models to study root canal fillings	15
Doxycycline‐functionalized polymeric nanoparticles inhibit Enterococcus faecalis biofilm formation on dentine	15
Regenerative endodontic procedures for the treatment of necrotic mature teeth: A preliminary randomized clinical trial	15
Effects of melatonin on insulin signaling and inflammatory pathways of rats with apical periodontitis	15
Outcomes reporting in systematic reviews on vital pulp treatment: A scoping review for the development of a core outcome set	15
Model system parameters influence the sodium hypochlorite susceptibility of endodontic biofilms	15
Association between dental factors and mortality	15
PROBE 2023 guidelines for reporting observational studies in Endodontics: A consensus‐based development study	15
Call for a review of diagnostic nomenclature and terminology used in Endodontics	14
Pulpotomy for treatment of complicated crown fractures in permanent teeth: A systematic review	14
Human amniotic membrane extracellular matrix scaffold for dental pulp regeneration in vitro and in vivo	14
Impact of root canal treatment on high‐sensitivity C‐reactive protein levels in systemically healthy adults with apical periodontitis – a preliminary prospective, longitudinal interventional study	14
A laboratory study of root canal and isthmus disinfection in extracted teeth using various activation methods with a mixture of sodium hypochlorite and etidronic acid	14
Bacteria and virulence factors in periapical lesions associated with teeth following primary and secondary root canal treatment	14
The presence of smear layer affects the antimicrobial action of root canal sealers	14
Diverse bacterial profile in extraradicular biofilms and periradicular lesions associated with persistent apical periodontitis	14
A critical review ofin vitroresearch methodologies used to study mineralization in human dental pulp cell cultures	14
Influence of occlusal and proximal caries on the outcome of full pulpotomy in permanent mandibular molar teeth with partial irreversible pulpitis: A prospective study	14
Research that matters: debunking the myth of the “fracture resistance” of root filled teeth	14
Tooth survival following root canal treatment by general dental practitioners in a Swedish county – a 10‐year follow‐up study of a historical cohort	14
The management of deep caries in UK primary care: A nationwide questionnaire‐based study	14
Preferred Reporting items for OBservational studies in Endodontics (PROBE) guidelines: a development protocol	14
PRIASE 2021 guidelines for reporting animal studies in Endodontology: explanation and elaboration	14
Present status and future directions: Management of curved and calcified root canals	14
Endodontic inflammatory disease: A risk indicator for a first myocardial infarction	14
How is carious pulp exposure and symptomatic irreversible pulpitis managed in UK primary dental care?	14
Present status and future directions: Imaging techniques for the detection of periapical lesions	13
Effect of photobiomodulation on post‐operative symptoms in teeth with asymptomatic apical periodontitis treated with foraminal enlargement: A randomized clinical trial	13
External cervical resorption – Treatment outcomes and determinants: A retrospective cohort study with up to 10 years of follow‐up	13
The prescribing of antibiotics for endodontic infections by dentists in Turkey: a comprehensive survey	13
Influence of metal artefact reduction tool on the detection of vertical root fractures involving teeth with intracanal materials in cone beam computed tomography images: A systematic review and meta‐a	13
Influence of rotational speed on torque/force generation and shaping ability during root canal instrumentation of extracted teeth with continuous rotation and optimum torque reverse motion	13
Impact of motion artefacts and motion‐artefact correction on diagnostic accuracy of apical periodontitis in CBCT images: an ex vivo study in human cadavers	13
A critical analysis of research methods and experimental models to study the load capacity and clinical behaviour of the root filled teeth	13
Electrokinetic transport and distribution of antibacterial nanoparticles for endodontic disinfection	13
Frightened of the pulp? A qualitative analysis of undergraduate student confidence and stress during the management of deep caries and the exposed pulp	13
Evaluation of the biological properties of two experimental calcium silicate sealers: an in vivo study in rats	13

Contrast‐enhanced micro‐CT to assess dental pulp tissue debridement in root canals of extracted teeth: a series of cascading experiments towards method validation	13
Influence of variations in the environmental pH on the solubility and water sorption of a calcium silicate‐based root canal sealer	13
The effect of different irrigation solutions and activation techniques on the expression of growth factors from dentine of extracted premolar teeth	13
Impact of several NiTi‐thermally treated instrumentation systems on biomechanical preparation of curved root canals in extracted mandibular molars	13
Vital pulp treatment for traumatized permanent teeth: A systematic review	13
Effectiveness of pulpotomy compared with root canal treatment in managing non‐traumatic pulpitis associated with spontaneous pain: A systematic review and meta‐analysis	12
Comparison of Bio‐C Pulpo and MTA Repair HP with White MTA: effect on liver parameters and evaluation of biocompatibility and bioactivity in rats	12
Influence of adjacent teeth restored with metal posts in the detection of simulated internal root resorption using CBCT	12
Effect of low‐level laser therapy on postoperative pain after single‐visit root canal retreatment of mandibular molars: A randomized controlled clinical trial	12
Inflammatory profile of apical periodontitis associated with liver fibrosis in rats: histological and immunohistochemical analysis	12
A bibliometric analysis of the top 100 most‐cited case reports and case series in Endodontic journals	12
Survival and prognostic factors of managing cracked teeth with reversible pulpitis: A 1‐ to 4‐year prospective cohort study	12
Effectiveness of diagnosing pulpitis: A systematic review	12
Patient satisfaction with root canal treatment and outcomes in the Swedish public dental health service: A prospective cohort study	12
Fracture incidence of WaveOne Gold files: a prospective clinical study	12
Evaluation of factors affecting the association between thickening of sinus mucosa and the presence of periapical lesions using cone beam CT	12
Excessive caffeine intake increases bone resorption associated with periapical periodontitis in rats	12
Irisin promotes odontogenic differentiation and angiogenic potential in human dental pulp cells	12
NLRP6‐caspase 4 inflammasome activation in response to cariogenic bacterial lipoteichoic acid in human dental pulp inflammation	12
Celecoxib treatment dampens LPS‐induced periapical bone resorption in a mouse model	12
A prospective cohort study evaluating the outcome of root canal retreatment in symptomatic mandibular first molars with periapical lesions	12
Enterococcus faecalis induces necroptosis in human osteoblastic MG63 cells through the RIPK3 / MLKL signalling pathway	12
Present status and future directions: Minimally invasive root canal preparation and periradicular surgery	12
Comparative analysis of the accuracy of periapical radiography and cone‐beam computed tomography for diagnosing complex endodontic pathoses using a gold standard reference – A prospective clinical stu	12
Effect of access cavity design on gaps and void formation in resin composite restorations following root canal treatment on extracted teeth	11
Effect of XP‐endo Shaper versus conventional rotary files on postoperative pain and bacterial reduction in oval canals with necrotic pulps: a randomized clinical study	11
Effect of preoperative oral administration of steroids in comparison to an anti‐inflammatory drug on postoperative pain following single‐visit root canal treatment – a double‐blind, randomized clinica	11
A laboratory study of the accuracy of three electronic apex locators: influence of embedding media and radiographic assessment of the electronic apical limit	11
Lipoteichoic acid stimulates the proliferation, migration and cytokine production of adult dental pulp stem cells without affecting osteogenic differentiation	11
Human three‐dimensional dental pulp organoid model for toxicity screening of dental materials on dental pulp cells and tissue	11
Minimally invasive access cavities: does size really matter?	11
Effectiveness of endodontic tissue engineering in treatment of apical periodontitis: A systematic review	11
Biological parameters, discolouration and radiopacity of calcium silicate‐based materials in a simulated model of partial pulpotomy	11
Influence of ethylenediaminetetraacetic acid on regenerative endodontics: A systematic review	11
Critical analysis of the reporting quality of randomized trials within Endodontics using the Preferred Reporting Items for RAndomized Trials in Endodontics (PRIRATE) 2020 quality standard checklist	11
Preserving dentine in minimally invasive access cavities does not strengthen the fracture resistance of restored mandibular molars	11
Effectiveness of revitalization in treating apical periodontitis: A systematic review and meta‐analysis	11
The influence of the addition of surfactants to sodium hypochlorite on the removal of hard tissue debris	11
A critical analysis of research methods and experimental models to study apical extrusion of debris and irrigants	11
A critical analysis of research methods to study clinical molecular biomarkers in Endodontic research	10
Outcomes reporting in systematic reviews on surgical endodontics: A scoping review for the development of a core outcome set	10
Ultrasound imaging for the differential diagnosis of periapical lesions of endodontic origin in comparison with histopathology – a systematic review and meta‐analysis	10
Bending, buckling and torsional resistance of rotary and reciprocating glide path instruments	10
Present status and future directions – Managing discoloured teeth	10
Inhibition of receptor‐interacting protein kinase‐3 in the necroptosis pathway attenuates inflammatory bone loss in experimental apical periodontitis in Balb/c mice	10
Exosomes derived from stem cells from the apical papilla alleviate inflammation in rat pulpitis by upregulating regulatory T cells	10
Apical pressures generated by several canal irrigation methods: A laboratory study in a maxillary central incisor with an open apex	10
Outcomes reporting in systematic reviews on non‐surgical root canal treatment: A scoping review for the development of a core outcome set	10
Effectiveness of root canal irrigation and dressing for the treatment of apical periodontitis: A systematic review and meta‐analysis of clinical trials	10
Surface and structural changes in root dentine by various chelating solutions used in regenerative endodontics	10
Epigenetic regulation of TLR2‐mediated periapical inflammation	10
Enterococcus faecalis sustained infection induces macrophage pro‐resolution polarization	10