International Endodontic Journal

Article	Citations
How do we and how should we deal with uncertainty in endodontics?	232
Patient record assessment of results and related resources spent during 1 year after initiation of root canal treatment in a Swedish public dental organization	200
Lipopolysaccharides and hydrogen peroxide induce contrasting pathological conditions in dental pulpal cells	155
A critical analysis of research methods and experimental models to study root canal fillings	130
Reduction of dual‐species biofilm after sonic‐ or ultrasonic‐activated irrigation protocols: A laboratory study	100
	81
Issue Information	74
Dynamic navigation: a laboratory study on the accuracy and potential use of guided root canal treatment	70
Abstracts	68
New associate editor for biological studies	64
Issue Information	62
RNA‐sequencing analysis reveals the potential molecular mechanism of RAD54B in the proliferation of inflamed human dental pulp cells	58
Issue Information	58
The outcome of full and deep pulpotomy in teeth with extremely deep carious lesion and symptomatic irreversible pulpitis: A non‐inferiority randomized controlled trial	53
Participation of fibroblast growth factor‐1 and interleukin‐10 in connective tissue repair following subcutaneous implantation of bioceramic materials in rats	52
	52
	50
Isthmus morphology influences debridement efficacy of activated irrigation: A laboratory study involving biofilm mimicking hydrogel removal and high‐speed imaging	49
Exploring approaches to pulp vitality assessment: A scoping review of nontraditional methods	48
Substance P/calcitonin gene‐related peptide and their receptors expression in human periodontal ligament after root canal preparation with five different systems	47
PRIDASE 2024 guidelines for reporting diagnostic accuracy studies in endodontics: A consensus‐based development	47
Issue Information	46
Issue Information	46
Editorial	45
The immune landscape in apical periodontitis: From mechanism to therapy	44

Response to Letter to Editor regarding article, ‘Association between dental factors and mortality’	43
Issue Information	42
Leaching and cytotoxicity of bismuth oxide in ProRoot MTA – A laboratory investigation	41
Effect of kinematics on the torque/force generation, surface characteristics, and shaping ability of a nickel‐titanium rotary glide path instrument: An ex vivo study	41
Does MTA provide a more favourable histological response than other materials in the repair of furcal perforations? A systematic review	41
	40
Editorial	39
Precision‐milled simulated curved root canals in bovine dentine for the assessment of chemo‐mechanical root canal preparation	39
Promoting integrity in scholarly research and its publication: International Endodontic Journal policy on reporting conflicts of interest, funding and acknowledgements within manuscripts submit	37
IWP‐2 modulates the immunomodulatory properties of human dental pulp stem cells in vitro	37
Influence of pulse energy, tip design and insertion depth during Er:YAG‐activated irrigation on cleaning efficacy in simulated severely curved complex root canal systems in vitro	36
Letter to the Editor	36
Long‐term prognosis for teeth with external cervical resorption based on periapical images and cone beam CT: A clinical study	35
Editorial	35
Non‐surgical root canal treatment and retreatment versus apical surgery in treating apical periodontitis: A systematic review	34
Effectiveness of root resection techniques compared with root canal retreatment or apical surgery for the treatment of apical periodontitis and tooth survival: A systematic review	34
	34
MicroRNA‐22 suppresses NLRP3/CASP1 inflammasome pathway‐mediated proinflammatory cytokine production by targeting the HIF‐1α and NLRP3 in human d	33
Influence of conservative endodontic access cavities on instrumentation of oval‐shaped straight root canals	33
Targeting hexokinase 1 alleviates NLRP3‐mediated inflammation in apical periodontitis: A laboratory investigation	32
Assessment of spin in abstracts of Endodontic Systematic Reviews with meta‐analyses published between 2010 and 2022. Are we in need of more transparent interpretation of findings?	32
Biocompatibility and bioactive potential of an experimental tricalcium silicate‐based cement in comparison with Bio‐C repair and MTA Repair HP materials	32
Physicochemical and functional properties of a novel clodronate‐containing chelating gel: A comparative in vitro study	31
Comparing the accuracy and treatment time of a robotic and dynamic navigation system in osteotomy and root‐end resection: An in vitro study	31
Abstracts	31
Angiogenic effects of Type 2 diabetes on the dental pulp	31
Issue Information	31
	30
Angiogenic and neurogenic potential of dental‐derived stem cells for functional pulp regeneration: A narrative review	30
Apical periodontitis microbiome association with salivary and serum inflammatory burden	30
Clinical outcome of guided endodontics versus freehand drilling: Comment	29
Pulp sensibility responses following complete and partial pulpotomy in mature permanent molars with carious pulpal exposure and symptomatic irreversible pulpitis: Analysis of pooled data from three ra	29
Next generation antibacterial strategies for regenerative endodontic procedures: A scoping review	28
Innate immune sensing of nucleic acid in endodontic infection	26
The effect of ultrasonic and multisonic irrigation on root canal microbial communities: An ex vivo study	26
Calcium hydroxide‐loaded nanoparticles dispersed in thermosensitive gel as a novel intracanal medicament	26
Effect of treatment with resiniferatoxin in an experimental model of pulpal inflammatory in mice	26
	25
Gender diversity in endodontics: Women's representation at recent biennial meetings	25
Detrimental effects of chronic sugar‐sweetened carbonated soft drink consumption on inflammatory response and the size of apical periodontitis: An animal‐based study	25
Preclinical 3D‐printed laboratory simulation of deep caries and the exposed pulp reduced student anxiety and stress, while increasing confidence and knowledge in vital pulp treatment	24
How does gender influence student learning, stress and career choice in endodontics?	24
The shaping ability of WaveOne Gold, TRUShape and XP‐endo Shaper systems in oval‐shaped distal canals of mandibular molars: A microcomputed tomographic analysis	23
Outcome measures to assess the effectiveness of endodontic treatment for pulpitis and apical periodontitis for use in the development of European Society of Endodontology S3‐level clinical practice gu	23
Activin a regulates vascular formation and stabilization in direct coculture of dental pulp stem cells and endothelial cells	23
Dental and endodontic‐related stress amongst undergraduate students before and during the COVID‐19 pandemic: A mixed‐methods study	23
Proteomic analysis of infected root canals with apical periodontitis in patients with type 2 diabetes mellitus: A cross‐sectional study	22
The efficacy of premixed bioceramic sealers versus standard sealers on root canal treatment outcome, extrusion rate and post‐obturation pain: A systematic review and meta‐analysis	22
Melatonin decreases plasma TNF‐α and improves nonenzymatic antioxidant defence and insulin sensitivity in rats with apical periodontitis fed a high‐fat diet	22
Methodological quality of umbrella reviews in endodontics: A cross‐sectional study	22

Root filled teeth in two parallel Danish cohorts: A repeated longitudinal cohort study	22
Two‐ and three‐dimensional healing assessment after endodontic microsurgery in through‐and‐through periapical lesions: 5‐year follow‐up from a randomized controlled trial	22
Explaining the working mechanism of laser‐activated irrigation and its action on microbial biofilms: A high‐speed imaging study	21
Issue Information	21
Diagnosis consensus among endodontic specialists and general practitioners: An international survey and a proposed modification to the current diagnostic terminology	21
	21
The bioceramic sealer iRoot SP promotes osteogenic differentiation of human stem cells from apical papilla via miR‐141‐3p/SPAG9/MAPK signalling pathway	20
Early life stress exacerbates bone resorption and inhibits anxiety‐like behaviour induced by apical periodontitis in rats	20
Role of TLR9 methylation on its active transcription in apical inflammation	20
Intracellular bacterial eradication using a novel peptide in vitro	20
Immunomodulatory effect of IL‐1RA in LPS‐activated macrophage/dental pulp stem cells co‐culture	19
MiR‐143‐5p regulates the proangiogenic potential of human dental pulp stem cells by targeting HIF‐1α/RORA under hypoxia: A laboratory investigation in pulp regeneratio	19
Patient‐related outcomes and Oral Health‐Related Quality of Life in endodontics	19
Comparative analysis of methods for measuring root canal curvature based on periapical radiography: A laboratory study	19
Present status and future directions: Removal of fractured instruments	19
How does orthodontic tooth movement influence the dental pulp? RNA‐sequencing on human premolars	19
Rev‐erbα attenuates refractory periapical periodontitis via M1 polarization: An in vitro and in vivo study	19
TNF‐alpha gene promoter's hypomethylation mediates a pro‐inflammatory phenotype in peripheral blood monocytes from apical periodontitis individuals	18
Effect of preemptive use of a nonsteroidal anti‐inflammatory drug and a corticosteroid on the efficacy of inferior alveolar nerve blockade and postoperative pain control in endodontic treatment of mol	18
Teeth with vital pulps and stage III periodontitis unresponsive to therapy exhibit a pulpal inflammatory profile similar to symptomatic irreversible pulpitis	18
Evaluation of bacterial anti‐adhesion and sustained antimicrobial abilities of chlorhexidine gluconate‐loaded phase‐transited lysozyme nanoparticle suspension on dentine: An ex vivo study	18
New Associate Editor for microbiology and irrigation studies	18
Accuracy of 3‐dimensional surgical guide for endodontic microsurgery with a new design concept: A cadaver study	18
Inflammatory microenvironment of moderate pulpitis enhances the osteo‐/odontogenic potential of dental pulp stem cells by autophagy	17
Growth factor release and dental pulp stem cell attachment following dentine conditioning: An in vitro study	17
The effectiveness of partial pulpotomy compared with full pulpotomy in managing deep caries in vital permanent teeth with a diagnosis of non‐traumatic pulpitis	17
A critical analysis of research methods and experimental models to study irrigants and irrigation systems	17
Influence of variations in the environmental pH on the solubility and water sorption of a calcium silicate‐based root canal sealer	17
Targeted metabolomics analysis approach to unravel the biofilm formation pathways of Enterococcus faecalis clinical isolates	17
Present status and future directions: Endodontic management of traumatic injuries to permanent teeth	16
A critical analysis of research methods to study clinical molecular biomarkers in Endodontic research	16
Prevalence of apical periodontitis in patients with autoimmune diseases: A case‐control study	16
Outcome of selective root canal retreatment—A retrospective study	16
Efficacy of four local anaesthesia protocols for mandibular first molars with symptomatic irreversible pulpitis: A randomized clinical trial	16
Endodontic pulp revitalization in traumatized necrotic immature permanent incisors: Early failures and long‐term outcomes—A longitudinal cohort study	15
Top 100 most‐cited scientific articles in regenerative endodontics 2019–2023: A bibliometric analysis	15
Five decades of the International Endodontic Journal: Bibliometric overview 1967–2020	15
Inflammatory profile of apical periodontitis exacerbated by cigarette smoke inhalation: Histological and immunohistochemical analysis in rats	15
One‐year outcome of selective caries removal versus pulpotomy treatment of deep caries: A pilot randomized controlled trial	15
Effectiveness of root canal instrumentation for the treatment of apical periodontitis: A systematic review and meta‐analysis	15
InternationalEndodonticJournal policy on mandatory prospective (a priori) protocol registration for clinical trials and systematic reviews	15
A critical analysis of research methods and experimental models to study working length determination and the performance of apex locators – A narrative review with recommendations for the future	15
How is carious pulp exposure and symptomatic irreversible pulpitis managed in UK primary dental care?	14
A critical analysis of research methods and biological experimental models to study pulp regeneration	14
Dental Trauma – A practical guide to diagnosis and managementEdited by DjemalSerpil, London & New Delhi: JP Medical Publishers, ISBN: 978‐1‐909836‐66‐2.	14
External cervical resorption – Treatment outcomes and determinants: A retrospective cohort study with up to 10 years of follow‐up	14
The financial and quality of life impact of urgent dental presentations: A cross‐sectional study	14
Periapical and endodontic status of patients with inflammatory bowel disease: Age‐ and sex‐matched case–control study	14
Present status and future directions of intracanal medicaments	14
Potential relationship between clinical symptoms and the root canal microbiomes of root filled teeth based on the next‐generation sequencing	14
The effects of dimethyl fumarate on cytoplasmic LPS‐induced noncanonical pyroptosis in periodontal ligament fibroblasts and dental pulp cells	14
Regenerative endodontic therapy for external inflammatory lateral resorption following traumatic dental injuries: Evidence assessment of best practices	14
Effect of photobiomodulation on post‐operative symptoms in teeth with asymptomatic apical periodontitis treated with foraminal enlargement: A randomized clinical trial	14
Clinical and radiographic outcomes of regenerative endodontic procedures for traumatized permanent necrotic teeth with apical periodontitis and external root resorption	13
Hsa‐miRNA‐143‐3p regulates the odontogenic differentiation of human stem cells from the apical papilla by targeting NFIC	13
Quasi‐3D dynamic photoelastic analysis of stress distribution during preparation of simulated canals with 13 mechanical preparation systems	13
Novel pain assessment tool specific for pulp symptoms to aid diagnosis	13
The induction of inflammation by the cGAS–STING pathway in human dental pulp cells: A laboratory investigation	13
Primary apical periodontitis correlates to elevated levels of interleukin‐8 in a Swedish population: A report from the PAROKRANK study	13
Psycho‐social perspectives of nonsurgical versus surgical endodontic interventions in persistent endodontic disease	13
	13
Prevalence of periapical lesions, root canal treatments and restorations in teeth adjacent to implant‐ or tooth‐supported crowns: A multi‐centre cross‐sectional study	13
Author Index	13
New consultant statistical advisor	13
Cemental tear: Literature review, proposed classification and recommendations for treatment	13
Response to the letter regarding our article, ‘Potential predisposing features of external cervical resorption: An observational study’ (Patel et al., 2025)	12
Exploring access cavity through non‐carious cervical lesions: Impacts on instrumentation, obturation, and fracture resistance in mandibular incisors	12
Pre‐medical assessment of root–canal–filled teeth with asymptomatic apical periodontitis—A multifaceted balancing act	12
DLX6‐AS1 regulates odonto/osteogenic differentiation in dental pulp cells under the control of BMP9 via the miR‐128‐3p/MAPK14 axis: A laboratory	12
How epigenetics and miRNA affect gene expression in dental pulp inflammation: A narrative review	12
Issue Information	12
	11
Issue Information	11
Synthesis of silver core‐shell nanoparticles and their influence on an experimental resin endodontic sealer: An in vitro analysis	11
Issue Information	11
Issue Information	11
Issue Information	11
Osteopontin interacts with dendritic cells and macrophages in pulp inflammation: Comprehensive transcriptomic analysis and laboratory investigations	11
New associate editor for case reports and launch of opinion/perspective articles	11
	11

	11
Case complexity of root canal treatments accepted for training in a secondary care setting assessed by three complexity grading systems: A service evaluation	11
Is canal overinstrumentation able to produce apical root dentinal microcracks in extracted teeth?	11
	11
Editor‐in‐Chief thanks the associate editors, editorial board and referees	11
The effect of low‐level laser therapy on the success rate of inferior alveolar nerve blocks in mandibular molars with symptomatic irreversible pulpitis: A randomized clinical trial	11
	11
A multi‐national survey‐based evaluation of undergraduate/predoctoral endodontic education	11
Outcomes reporting in systematic reviews on non‐surgical root canal treatment: A scoping review for the development of a core outcome set	10
Selenium ameliorates inflammation by decreasing autophagic flux and mitogen‐activated protein kinase signalling on experimentally induced rat periapical lesions	10
	10
Author Index	10
Development and preliminary validation of an Objective Structured Assessment of Technical Skills (OSATS) for a partial pulpotomy procedure	10
Volumetric changes in root canal sealers in ex vivo and a novel animal model approach	10
The expression of cyclic GMP–AMP synthase in human apical periodontitis: A laboratory investigation	10
Laboratory simulation of longitudinally cracked teeth using the step‐stress cyclic loading method	10
Issue Information	10
Excessive caffeine intake increases bone resorption associated with periapical periodontitis in rats	10
Micro‐computed tomographic evaluation of dentinal microcracks in response to progressive taper enlargement in root canals of maxillary molars	10
Exploring access cavity through non‐carious cervical lesions: Impacts on instrumentation, obturation and fracture resistance in mandibular incisors	10
Effect of red wine or its polyphenols on induced apical periodontitis in rats	10
Efficacy of the GentleWave System in the removal of biofilm from the mesial roots of mandibular molars before and after minimal instrumentation: An ex vivo study	10
Issue Information	10
In vitro assessment of antimicrobial potential of low molecular weight chitosan and its ability to mechanically reinforce and control endogenous proteolytic activity of dentine	10
Association between apical periodontitis and psoriasis vulgaris: A cross‐sectional study	10
Issue Information	10
Curcumin reduces inflammation in rat apical periodontitis	10
Mapping the periapex anatomical pattern of teeth involved in sodium hypochlorite accidents: a cross‐sectional quasi‐experimental study	9
Multimethod analysis of large‐ and low‐tapered single file reciprocating instruments: Design, metallurgy, mechanical performance, and irrigation flow	9
Well‐being, postoperative pain and outcome after clinical application of a novel root canal irrigation fluid—RISA—in teeth with apical periodontitis: A first‐in‐human study	9
A priori power considerations in Endodontic Research. Do we miss the timeline?	9
Cytocompatibility and bioactive potential of AH Plus Bioceramic Sealer: An in vitro study	9
In vitro inflammatory modulation of bioceramic endodontic sealer in macrophages stimulated by bacterial lipopolysaccharide	9
In vitro response of dental pulp stem cells to dural substitute grafts: Analysis of cytocompatibility and bioactivity	9
Efficacy of a novel remotely‐generated ultrasonic root canal irrigation system for removing biofilm‐mimicking hydrogel from a simulated isthmus model	9
Periapical healing following endodontic microsurgery with collagen‐based bone‐filling material: A randomized controlled clinical trial	9
Outcomes reporting in systematic reviews on revitalization: A scoping review for the development of a core outcome set	9
A critical analysis of research methods and experimental models to study apical extrusion of debris and irrigants	9
Expression of PINK1 and Parkin in human apical periodontitis	9
Expression of chronic pain genes in apical periodontitis tissues	9
In‐depth investigation of FAM20A insufficiency effects on deciduous dental pulp cells: Altered behaviours, osteogenic differentiation, and inflammatory gene expression	9
The importance of establishing a core outcome set for endodontic clinical trials and outcomes studies	9
Global survey of endodontic practice and adoption of newer technologies	9
The use of electrodermal activity in pulpal diagnosis and dental pain assessment	9
Effectiveness of D,L‐2‐hydroxyisocaproic acid (HICA) and alpha‐mangostin against endodontopathogenic microorganisms in a multispecies bacterial–fungal biofilm in anex vivotooth model	9
Clinical decision making of post‐treatment disease	9