Placenta

Article	Citations
A 3D culture model to study uterine gland cells as signaling agents in embryo-endometrium relationship	77
Editorial Board	58
Effect of heat stress during late gestation on placentome morphometry of multiparous dairy cattle in a pasture-based system	52
Exploring Placental DNA Methylation in IVF Pregnancies Reveals Male-Specific CpG Signatures and Increased Female Variability	49
Effects of Placenta-Derived Factors on Maternal Megakaryocytes and Thrombopoiesis	43
Swine trophoblast organoids as a robust, physiologic model of porcine placental development	41
Targeted delivery of liposomes to the uterine artery of pregnant rhesus macaques	36
Chronic gestational inflammation: Comparisons of obesity-mediated and preeclampsia-mediated placental inflammation using transcriptomic and histological methods	34
Immunosuppressant drug tacrolimus inhibits HUVEC angiogenesis and production of placental growth factor	33
Characterization and in vitro modeling of trophoblast and villous core networks of human first trimester placental cells	31
Medroxyprogesterone Acetate Suppresses Inflammatory Cytokine Expression in Amniotic Mesenchymal Cells	31
IFPA Pages	30
Placental pathological findings in triplet pregnancies conceived through assisted reproductive technology: a study of 98 cases	30
Novel 3D in vitro human placenta-on-a-chip model derived using human trophoblast stem cells differentiated towards syncytiotrophoblasts and extravillous trophoblasts to mimic both villi and implantati	29
Pneumocystis is a frequent fungal colonizer of the human placenta at term	29
Detection of heat-stable antibacterial activity in cotyledonary and discoid placentas	29
Composition of circulating short-chain fatty acids in gestational diabetes mellitus and their associations with placental immune-metabolic responses	28
Lack of CB1 receptor reduces preterm birth rate in an LPS-induced murine model	27
A case of pregnancy-related acute kidney injury following a missed abortion	26
Necroptosis associates with infection severity and birth outcomes in placental malaria	25
Extracellular vesicle signalling and pregnancy- engineering the opportunities	25
Effects of high-fat diets on placenta and fetal development in female swiss mice	25
Fetoplacental vascular reactivity is altered in fetuses with congenital diaphragmatic hernia	25
Comparative study of sialic acid content in saliva between preeclampsia and normal gestation patients	24
Editorial Board	24

Development of novel AOX1 inhibitors to prevent or reverse placental oxidative damage	24
Maternal nutrient restriction in guinea pigs increases resistance in the umbilical artery at mid-gestation.	23
Pre-natal dietary imbalance of folic acid and vitamin B12 deficiency adversely impacts placental development and fetal growth	23
Higher long-term blood pressure in women with recurrent preeclampsia than who with single episode of preeclampsia	23
Analysis of podocyte injury and inflammatory response in a mouse model of preeclampsia using electron microscopy	23
Unveiling placental development in circadian rhythm-disrupted mice: A photo-acoustic imaging study on unstained tissue	23
Placental deficiency during maternal SARS-CoV-2 infection	22
The overview of lactylation in the placenta of preeclampsia	22
Achieving multifunctionality in a single, tissue-sized syncytiotrophoblast cell in humans	21
Presepsin in the amniotic fluid is a useful clinical inflammatory biomarker for the prenatal predictive diagnosis of histologic chorioamnionitis: a retrospective preliminary study	21
Loss of HAPLN3 impairs trophoblast differentiation and invasion	20
Different risk of acute feto-fetal transfusion in basic clinical subtypes of monochorionic twins	20
Transplacental transfer of antibodies is modulated by IgG1 allotypes	20
Ferumoxytol-enhanced MRI of retroplacental clear space disruption in placenta accreta spectrum	20
High-fidelity, multimodal detection of microchimeric cells in their spatial context	20
Extracellular ATP regulates human syncytiotrophoblast formation by activating the P2X7 channel.	19
Membrane-bound mitochondrial DNA: a potential senescence signal in placenta tissue	19
Investigating Stem Cell Antigen-1 Expression and Effects in Mouse Trophoblast Stem Cells	19
Influence of Maternal Smoking on Premature Senescence and Antioxidative Capacity in the Placenta	19
Role of osteopontin (OPN) in uterine spiral artery remodeling	18
JQ1-mediated bromodomain inhibition reveals TREML2 as a master regulator of trophoblast fusion and identifies its decreased expression in preeclamptic placentas.	18
Insights into embryo-endometrium immune interactions	18
MICROPLASTIC EXPOSURE ALTERS METABOLIC AND HORMONAL PROFILES IN HUMAN PLACENTAL EXPLANTS	18
Transplacental Passage of Ampicillin: Implications for Antenatal Therapy	18
Exosome enriched leucine-rich alpha-2-glycoprotein-1 and extracellular matrix protein 1 proteins induce abnormal placental angiogenesis in pregnant mice	17
Comprehensive analyses of DNA methylation of the TIMP3 promoter in placentas from early-onset and late-onset preeclampsia	17
Prediction of maternal and foetal outcomes among patients with preeclampsia using circulatory biomarkers (MMP-9 & ST2) - A prospective cohort study	17
Potential resolution of placenta previa from the 28th-to the 36th-week of pregnancy: A retrospective longitudinal cohort study	17
Gardnerella vaginalis impairs extravillous trophoblast invasion via extracellular matrix-mediated MMP2 downregulation	17
The whole is lesser than the sum of its parts? Dissecting layer-enriched samples of rodent placenta is worth the effort	17
Nitric oxide donor increases umbilical vein blood flow and fetal oxygenation in fetal growth restriction. A pilot study	17
“Optimal timing for RNA isolation: Recommendations for placenta sample collection under clinical conditions”	16
Editorial Board	16
Investigating the effects of beta blockers on fetal vasculature	16
Low oxygen-induced ferritinophagy is responsible for heightened ferroptosis in the placenta in fetal growth restriction	16
Characterization and in vitro modeling of trophoblast and villous core networks of human first trimester placental cells	16
Latent profile analysis of newborn dried blood spot (DBS) cyto-and chemo-kines and growth factors and maternal and fetal acute inflammatory responses to amniotic fluid infection.	16
Placenta accreta after hysteroscopic surgery for intrauterine adhesion	16
Placental extracellular vesicles induce ovarian tumour cell death in an ex vivo explant model: Possible therapeutic potential	16
Editorial Board	15
A novel technique to estimate intravillous fetal vasculature on routine placenta histologic sections	15
Association between maternal consumption of ultra-processed foods, lipid biomarkers of de novo lipogenesis in plasma and human milk, and postpartum depression: Investigation in a Brazilian cohort of p	15
Morphological and functional changes in placentas from prolonged pregnancies	15
Upregulation of METTL14 contributes to trophoblast dysfunction by elevating FOXO3a expression in an m6A-dependent manner	15
METTL3 suppressing SLC31A1 m6A modification regulates trophoblast migration and invasion	15
Spheroid formation induces chemokine production in trophoblast-derived Swan71 cells	15
Altered release of thrombomodulin and HMGB1 in the placenta complicated with preeclampsia	15
Velocity-selective arterial spin labeling perfusion measurements in 2nd trimester human placenta with varying BMI	15
Metformin ameliorates trophoblastic immunometabolic disorders via attenuating TLR4/NF-κB signaling through ATXN7L3-mediated histone H2B monoubiquitination	14
The differential placental expression of ERp44 and pre-eclampsia; association with placental zinc, the ERAP1 and the renin-angiotensin-system	14

Trophoblast-mediated spatial changes in hydrogel matrix properties	14
DNMT1-mediated DNA methylation contributes to CYP11A1 expression in progesterone synthesis in placental trophoblast syncytialization	14
Trypanosoma cruzi induced trophoblast differentiation is mediated by MIR-19B	14
The impact of maternal Zika virus infection on long-term neurodevelopment:	14
Placental pathology findings amongst extremely preterm perinatal deaths in Aotearoa New Zealand	14
Butyrate increases maternal liver lipid accretion and ameliorates fetal markers of fatty liver programming	14
Deep learning for fetal inflammatory response diagnosis in the umbilical cord	14
Are there differences between monochorionic twin placentas after spontaneous and assisted conception?	14
Single-cell RNA sequencing reveals altered placental microenvironment due to maternal high-fat diet	14
Stress regulation of WFS1 and PERK-p-eIF2α-ATF4 signaling pathway in placental tissue cells of intrahepatic cholestasis of pregnancy	14
Editorial Board	13
A retrospective study of manual removal or expectant management for retained product of conception after the third trimester delivery	13
Placental Aquaporin-3: A potential molecular target for aspirin in the treatment of preeclampsia	13
Corrigendum to PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling [Placenta 130 (2022) 25–33]	13
The production of angiogenic and antiangiogenic factors via the activation of protein kinase C in the placenta of pregnant diabetic mice	13
COVID in pregnancy: Biomarkers of placental dysfunction and neonatal outcomes	13
Gestational chronodisruption and its role in fetal programming of non-communicable diseases	13
Role of bacterial chorioamnionitis in the physiopathology of neurodevelopmental disorders of the offspring	13
Letter to the editor on “The MRI estimations of placental thickness and cervical length correlate with postpartum hemorrhage (PPH) in patients with risk for placenta accreta spectrum (PAS) disorders”	13
The role of glutamitc oxaloacetic transaminase in placentas of pregnancies complicated with IUGR	13
Developing of a novel therapeutic agent for FGR through Drug repositioning	13
Protocol for the quantitative analysis of images retrieved by multiplex immunofluorescence staining to allow cell type-specific spatial phenotyping of markers of interest in the human placenta	12
Supercomplex assembly supports higher mitochondrial bioenergetic capacity of cytotrophoblasts, compared to the syncytiotrophoblast.	12
Placental human papillomavirus infections and adverse pregnancy outcomes	12
Whole transcriptome analysis of trophoblasts under hypoxia	12
Assessment of placental transfer of IgG antibodies and cytokine production in response to a viral environment	12
Extracellular Vesicles: What are we actually studying?	12
Villitis of unknown etiology, chronic deciduitis, chronic chorioamnionitis and chronic histiocytic intervillositis in monozygotic and dizygotic twin pregnancies. A retrospective analysis of 16 cases	12
Hypoxia alters the proteome of small human placental extracellular vesicles and their effect on endothelial dysfunction.	12
Higher fetal membrane myo-inositol content associates with increased tensile strength linked with alterations in acylcarnitine lipids and hydroxyproline content	12
3D Virtual Histology of Placental Tissue – Whole Organ to Biopsies: Analysing Vasculature with an nnU-Net to Examine Pre-Eclamptic Placentas	12
Prenatal exposure to perceived stress, maternal asthma, and placental size	12
Human implantation: The complex interplay between endometrial receptivity, inflammation, and the microbiome	11
NNMT expression in preeclampsia: Analyses on placental tissues and cell lines	11
Small RNAs in the pathogenesis of preeclampsia	11
ARID1A recruits GATA2 to regulate the senescence of trophoblast cells under high-glucose condition	11
Hydrogen sulfide promotes migration of trophoblast cells by a Rho GTPase mediated actin cytoskeleton reorganization	11
Late gestation heat stress alters O2 regulation in placenta and neonatal heifers	11
ASCT2-dependent secretion mechanism of the cell fusion-regulator suppressyn	11
Determination of residue aspirin and its bioactive metabolites in human placenta: Application to high-risk to preeclampsia women received prophylactic low-dose aspirin	11
Placental correlates in categories of preterm births based on gestational age	11
Chronic intervillositis of unknown etiology in patients with recurrent pregnancy loss: Impact on reproductive outcomes, treatment efficacy, and recurrence rates	11
Detecting abnormal placental microvascular flow in maternal and fetal diseases based on flow-compensated and non-compensated intravoxel incoherent motion imaging	11
Endotheliochorial placental glycosylation reflects evolutionary divergence between Felidae species (Felis catus and Panthera leo) and Canidae (Canis familiaris)	10
The influence of adiponectin in metabolic parameters of pregnant women with mild gestational hyperglycemia and gestational diabetes mellitus	10
Porphyromonas gingivalis lysate induces tissue disorganization and proinflammatory response in human placental explants	10
Analysis of Non-Coding RNAs in Placental Tissue and Extracellular Vesicles: Implications for Trophoblast Function	10
Deep proteomic characterization of placenta tissue from patients with preeclampsia	10
Buprenorphine and the placenta: does MAT in pregnancy impact placental efficiency?	10
HtrA4 is required for differentiation of human trophoblast stem cells into syncytiotrophoblast	10
Fibroblast activating protein (FAP) is reduced in FGR in regions of the villous tree with disturbed differentiation of perivascular myofibroblasts	10
Uteroplacental versus fetal use of glucose in healthy pregnancies at term. A human in vivo study	10
Clinical course of placenta accreta cases managed expectantly for seven days or longer	10
ZKSCAN1 expression in placentae of preeclampsia pregnant women: implications in the pathogenesis of preeclampsia	10
Differences in syncytiotrophoblast shear stress and mechanosensing protein expression in fetal growth restriction.	10
Transcriptional specialization of nuclei in the giant, multinucleated syncytiotrophoblast cell	10
The heart-placenta axis is dysregulated in a conditional Hand1 mutant model of FGR	10
Vaccination by a Zika purified inactivated virus both before and during pregnancy in the common marmoset monkey is associated with relatively normal placental morphology: a preliminary stereological a	10
Placentas from women of advanced maternal age (AMA) show increased activation of the unfolded protein response (UPR) but this is not exacerbated in the presence of Fetal Growth Restriction (FGR).	10
Single-cell spatial mapping of trophoblast subpopulations in the human placenta using HybISS	10
Trophoblast-specific overexpression of Slc7a5 (LAT1) causes fetal overgrowth by increasing fetal plasma levels of circulating essential amino acids	10
Excess folic acid mimics deficiency in human placenta in vitro	10
Cargo changes in placental extracellular vesicles due to antiphospholipid antibody treatment may reflect differential functionality of different vesicle subtypes	10
Title Page/Editorial Board	9
AQP4 and AQP9 positive-extracellular vesicles in preeclampsia	9
In vitro evaluation of the effect of oxygen concentrations on thrombomodulin expression in a first-trimester trophoblast cell line	9
HLA-G isoforms, HLA-C allotype and their expressions differ between early abortus and placenta in relation to spontaneous abortions	9
Ultrasound evaluation of pathophysiology in fetal thrombo-vasculopahy due to umbilical cord abnormalities	9
Characterizing placental NLRP3 inflammasome and lipidome dynamics: Insights from glucose, metformin, and LPS exposure in placental explants	9
The proinflammatory cytokines IFN-α and TNF-α inhibit extravillous trophoblast invasion	9
Placental dysfunction: The core mechanism for poor neurodevelopmental outcomes in the offspring of preeclampsia pregnancies	9
Molecular insights into the corin function at the uteroplacental interface	9
Upregulation of placental Ski-like proto-oncogene in preterm preeclampsia: potential target for preeclampsia treatment?	9
Follistatin dysregulation impaired trophoblast biological functions by GDF11-Smad2/3 axis in preeclampsia placentas	9
Novel approaches to obstetric drug design and development	9
Nutrition and neurodevelopment: Participation of vitamin E in the differentiation of the early brain	9
Cytotoxicity and induction of proinflammatory cytokines in placental explant cells following azathioprine exposure	9
Impact of tissue porosity and asymmetry on the oxygen uptake of the human placenta: A numerical study	9
Morphology and evolutionary aspects of the yolk sac in dogs	9
Gastroschisis associated changes in the placental transcriptome	9

Corrigendum to “Visual assessment of the placenta in antenatal magnetic resonance imaging across gestation in normal and compromised pregnancies: Observations from a large cohort study” [117 January 2	9
Comments on “Prenatal interventions for fetal growth restriction in animal models: A systematic review”	9
Editorial Board	9
Epigenetic effects of exercise on improving the adverse placental environment associated with maternal overweight and obesity	9
Activin A promotes human trophoblast invasion by upregulating integrin β3 via ALK4-SMAD4 signaling	9
A case of fetal growth restriction with placental confined mosaicism	9
Editorial Board	9
Characterization and expression of thyroid hormone transport in HTR8/SVneo trophoblast cells under hyperinsulinemia conditions	9
Polymorphisms of hypertension susceptibility genes as a risk factors of preeclampsia in the Caucasian population of central Russia	9
Placental weight as a predictor of future health: Insights from a large-scale genome-wide association study	9
IFPA Pages	9
The role of aryl hydrocarbon receptors in nutrient metabolism and immune regulation at the maternal–fetal interface	8
Pitfalls using scRNA seq and outlook to new technologies looking at the human placenta	8
The Placental Transcriptome Mediates the relationship between Prenatal Phthalate Exposure and Placental Efficiency	8
Meta-analysis on COVID-19-pregnancy-related placental pathologies shows no specific pattern	8
Trophoblast extracellular vesicles are a mechanistic link between preeclampsia and early cardiovascular mortality in women	8
SKAP2 is downregulated in the villous tissues of patients with missed abortion and regulates growth and migration in trophoblasts through the WAVE2-ARP2/3 signaling pathway	8
Maternal care of the whole litter improves the success rate of diabetes in pregnancy in rats	8
The role of STAT3 signaling in human placental extravillous trophoblast differentiation	8
Pulmonary trophoblastic deportation in the hystricomorph rodent Lagostomus maximus	8
Establishment of human trophoblast stem cells from term smooth chorion	8
OLFML3 suppresses trophoblast apoptosis via the PI3K/AKT pathway: A possible therapeutic target in preeclampsia	8
Placental complement component C5 levels are elevated in term preeclampsia - its inhibition does not mitigate placental dysfunction	8
Placenta Accreta Spectrum Biomarker Discovery Using DIA-MS Proteomic Analysis of Extracellular Vesicle Enriched Fractions	8
Comparative effects of bisoprolol and nebivolol on fetoplacental vascular tone	8
Microplastic accumulation in placentas and umbilical cords from pregnancies in Brazil	8
Explorative 3-D culture of early secondary follicles in a time lapse system for up to 36 days gives valuable, but limited insights in follicular development	8
Identifying and Characterizing Membrane-Binding Partners of the Placental Homing Peptide NKG	8
Maternal, placental, and fetal distribution of titanium after repeated titanium dioxide nanoparticle inhalation through pregnancy	8
An ex vivo model for studying regulated cell death in syncytiotrophoblast using human placental explants	8
Ectonucleotidases and purinergic signaling might contribute to immunosuppression in newborns	8
Adipokine visfatin as a response of an efficient placenta to key pregnancy risk factors	8
Sociodemographic and clinical profiles associated with preeclampsia: Comparison between Argentinean and Mexican women cohorts	8
The role of creatine in placental energy metabolism at birth: Initial insights from the Creatine and Pregnancy Outcomes (CPO) cohort study of low-risk pregnancy	8
Antenatal melatonin supplementation increases fetal weight and reduces placental oxidative damage in a mouse model of advanced maternal age	8
First trimester extravillous trophoblast secretes HLA class I molecules via small extracellular vesicles	8
Placental pathology findings in perinatal deaths from 28 weeks gestation in Aotearoa New Zealand	7
Artery-to-vein anastomoses in unequally divided placentas and their association with birthweight discordance	7
Placental transfer and metabolism of betamethasone in healthy and preeclamptic human placentas	7
Characterization of micro-haemodynamics in the placental intervillous space by integrated experimental and theoretical approaches	7
Chronic inflammation of the male genital tract impairs female genital tract immunomodulation and decrease fertility potential	7
Sexually dimorphic alterations in placental senescence pathways in Gestational Diabetes Mellitus (GDM)	7
Clinical Significance of stage 1 Maternal inflammatory response in placenta	7
Role of exosomes in placenta-maternal body axis for organ specific damage of preeclampsia	7
Placental metabolomics from women with gestational diabetes mellitus unveils glycolytic and one-carbon metabolism impairment	7
Melatonin-treated trophoblast extracellular vesicles signaling mediates macrovascular and microvascular endothelial cell migration	7
Unravelling the Protective Role of Placental ACE2 During Chronic Hypoxia/Reoxygenation	7
A case of high-grade VUE diagnosed by additional immunostaining rather than H&E staining alone	7
Placental assessment using spectral analysis of the envelope of umbilical venous waveforms in sheep	7
miR-2115-3p inhibits ferroptosis by downregulating the expression of glutamic-oxaloacetic transaminase in preeclampsia	7
Placental damage in pregnant women with SARS-CoV-2 infection: Comment	7
Levels of mtDNA, mitofusin -2 and presence of lipid vacuole in the placental tissue of obese pregnant women	7
Analyzing the Relationship Between Preeclamptic Severity and Placental Methylation	7
Maternal disadvantage and pregnancy outcomes in two Australian pregnancy cohorts	7
Placental lesions induced by Omicron SARS-CoV-2 in a pregnant woman treated with anti-CD20	7
Volume analysis and three-dimensional imaging of the migration process of bovine trophoblast giant cells at mid and end of gestation	7
Dissecting the microenvironment of gestational trophoblastic disease through deconvolution of bulk RNA-seq data	7
Trend: A test for recurrent implantation failure patients’ detection by qPCR array	7
Exposure to fine particulate matter 2.5 from wood combustion smoke causes vascular changes in placenta and reduces fetal size	7
Mid-late gestation leptin infusion induces placental mitochondrial and endoplasmic reticulum unfolded protein responses in a mouse model of preeclampsia	7
Maternal dietary olive oil protects diabetic rat offspring from impaired uterine decidualization	7
Second trimester cell-free placental DNA methylation profiles in preterm birth subtypes	7
Author index	7
Maternal C1q deficiency leads to impaired decidual vascular remodelling, placental insufficiency and reduced fetal growth.	7
Astrocyte and microglia activation by circulating extracellular vesicles from preeclampsia exacerbates blood-brain barrier disruption on a microfluidic BBB-on-chip model	7
Genetic profiling of Plasmodium falciparum antigenic biomarkers among asymptomatic pregnant women on intermittent preventive treatment with sulfadoxine-pyrimethamine from southwest Nigeria	7
Fetal growth restriction and a single umbilical artery are independent predictors of hypospadias during pregnancy	7
Editorial Board	7
Oxidative stress microenvironment responsive multifunctional nanoparticles for targeted prevention and treatment preterm birth caused by placental inflammation	7
Increased NPC1 and STARD3 expression in placentas from women with Maternal Supraphysiological Hypercholesterolemia (MSPH) promotes lysosomal and mitochondrial dysfunction.	7
Cesarean scar pregnancy successfully managed to third-trimester	7
Circular RNAs (circRNAs) cause DNA damage and characterise accelerated ageing in stillbirth placenta	7
Vitamin D metabolites and oxidized polyunsaturated fatty acids in plasma and human milk: Implications for the metabolic and mental health of the mother and infant development in the first six months p	7
Attenuation of murine placental MDR1 and BCRP functions by their unique protein localization	7
Immunoregulation of the decidualization program: Impact of the reticular stress and senescence in endometrial receptivity	6
Fluidic cellular in vitro model resembling the maternal-fetal interface	6
1,25(OH)2D3 alleviates LPS-induced preeclampsia-like rats impairment in the protective effect by TLR4/NF-kB pathway	6
Developmental programming of the offspring´s health and disease by maternal obesity	6
Viruses may cause a significant proportion of chronic inflammatory pathology in the placenta	6
Third-trimester side-population trophoblasts can be differentiated to mature trophoblast lineages and show reduced growth in FGR.	6
First trimester placental extracellular vesicles likely contribute to the vasodilation of maternal resistance arteries in normal pregnancy	6
Maternal Folate Status and the Prevalence of Gestational Diabetes Mellitus: Insights from Australian Pregnancy Cohorts	6
Compensatory expansion of the cotyledonary surface in response to nutritional restriction in multiparous pregnant beef cows	6
Obituary to the IFPA Journal: Placenta - Date: August 16, 2024	6
Transmission electron microscopy demonstration of reduced endothelial glycocalyx in severe preeclampsia	6
Hypoxic placental small extracellular vesicles disrupt the blood-brain barrier in the frontal area of the brain	6
Gelatin methacryloyl biomaterials and strategies for trophoblast research	6
Joan Hunt Senior award lecture: New tools to shed light on the ‘black box’ of pregnancy	6
The study of clinical outcome in cases of placenta previa	6
Placenta in ZIKV infection: From women to mice	6
Investigating the effects of microplastic accumulation on women's health during pregnancy	6
Integrated placental and neonatal urinary detection of Ureaplasma urealyticum: A translational approach to predicting adverse neonatal outcomes	6
Regulatory mechanisms underlying endoplasmic reticulum stress involvement in the development of gestational diabetes mellitus entail the CHOP-PPARα–NF–κB pathway	6
Thinking outside the box: The placenta responds to injury with proinflammatory cytokines even when the environment is immunosuppressive	6
Comprehensive Analysis of decidua in ectopic pregnancies reveals role of ATG2A	6