Cell Calcium

Article	Citations
TRPM7 in neurodevelopment and therapeutic prospects for neurodegenerative disease	53
Regulating calcium flux through AMPA glutamate receptors	45
Commentary on: Li et al.; Ca2+ transients on the T cell surface trigger rapid integrin activation in a timescale of seconds. Nature Communications (2024)	44
Arriving at the next level of complexity in IP3R and SOCE signaling	41
Store-operated ion channels: A growing family ?	34
Rapid quantification of intracellular calcium stores reveals effects of membrane micropeptides on SERCA function	32
Protein diversity in store-operated calcium entry components and their related variants	31
Rapid Quantification of First and Second Phase Insulin Secretion Dynamics using an In vitro Platform for Improving Insulin Therapy	30
Acidic Ca2+ stores and immune-cell function	30
Cristae junction as a fundamental switchboard for mitochondrial ion signaling and bioenergetics	29
ZnT1 is a neuronal Zn2+/Ca2+ exchanger	29
Insulin-like growth factor-1 regulates the mechanosensitivity of chondrocytes by modulating TRPV4	29
Characterization of a functional Ca2+ toolkit in urine-derived stem cells and derived skeletal muscle cells	28
Editorial Board	28
The IP3 receptor-KRAP complex at the desmosomes: A new player in the apoptotic process	28
Dyclonine inhibition of TRPV3: From functional discovery to structural insight	27
How do MICUs gate the mitochondrial calcium uniporter?	27
Abnormal calcium activity and CREB phosphorylation are associated with motor memory impairment in presenilin-1 mutant knock-in mice	26
STIM1: A new player in nuclear dynamics? Lessons learnt from tubular aggregate myopathy	25
MICU1 and MICU2, two peas in a pod or entirely different fruits?	24
Relevance of lysosomal Ca2+ signalling machinery in cancer	23
A role for lysosomal calcium channels in mitigating mitochondrial damage and oxidative stress	23
Macrophage migration inhibitory factor induces phospholamban phosphorylation in cardiac muscle	22
Calcium signals as regulators of ferroptosis in cancer	22
Role of auditory-somatosensory corticothalamic circuit integration in analgesia	22

TRPC3 governs the spatiotemporal organization of cellular Ca2+ signatures by functional coupling to IP3 receptors	22
NAADP-mediated calcium release promotes angiopoietin 2 secretion by regulating Rab46-dependent Weibel-Palade body trafficking	21
Histamine 1 receptors and reverse-mode Na+/Ca2+ exchanger drive extracellular Na+-dependent intracellular Ca2+ oscillations in human cerebrovascular endothelial cells	19
STIMulating IRE1: How store-operated Ca2+ entry intersects with ER proteostasis	18
Proton-modulated interactions of ions with transport sites of prokaryotic and eukaryotic NCX prototypes	18
Optical profiling of autonomous Ca2+ nanodomains generated by lysosomal TPC2 and TRPML1	18
Catching the next wave of recombinant RyR2 cryo-EM structures. Commentary on “Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations”	18
Editorial Board	17
PIP2 primes IP3 receptor activity: It takes at least three IP3s to open!	17
Intersection between calcium signalling and epithelial-mesenchymal plasticity in the context of cancer	17
Editorial Board	17
High resolution cryo-EM structures of TRPC5-Gαi3 complexes reveal direct activation of an ion channel by Gαi-GTP	17
Editorial Board	17
Endolysosomal calcium release and cardiac physiology	16
Remodelling of Ca2+ homeostasis is linked to enlarged endoplasmic reticulum in secretory cells	16
Increased matrix stiffness suppresses ATP-induced sustained Ca2+ influx in MDA-MB-231 breast cancer cells	16
Editorial Board	16
The tether function of the anoctamins	16
Ca2+ transients in ICC-MY define the basis for the dominance of the corpus in gastric pacemaking	16
TRPV1 signaling in skeletal muscle: A mini review of physiological and pathological roles	16
The role of SERCA in vascular diseases, a potential therapeutic target	16
Glucose-induced [Ca2+]i oscillations in β cells are composed of trains of spikes within a subplasmalemmal microdomain	16
The PHATE of basal epidermal cells: Calcium signaling during the cell cycle	15
IP3 receptors: An “elementary” journey from structure to signals	15
Bcl-xL and IP3R interaction: Intimate relationship with an uncertain outcome	15
Editorial Board	15
Editorial Board	15
Endoplasmic reticulum-mitochondria lockdown in Wolfram syndrome	15
Simultaneous TIRF imaging of subplasmalemmal Ca2+ dynamics and granule fusions in insulin-secreting INS-1 cells reveals coexistent synchronized and asynchronous release	14
Editorial Board	14
GPCR signalling: Yet another variant route in a highly complex road map	14
Transcriptional, biochemical, and immunohistochemical analyses of CaMKKβ/2 splice variants that co-localize with CaMKIV in spermatids	14
Spicy Science: Structural snapshots of a polymodal nociceptor reveal insights on our sensation to pain, heat, and taste.	14
STIM1 and ORAI1 mutations leading to tubular aggregate myopathies are sensitive to the Store-operated Ca2+-entry modulators CIC-37 and CIC-39	14
Killing in the name of: Reversing epigenetic silencing of ITPR3 to succumb cancer cells’ resistance to chemotherapeutics	13
Editorial Board	13
Calcium signaling and genetic rare diseases: An auditory perspective	13
Editorial Board	13
Pannexin 1 plays a pro-survival role by attenuating P2X7 receptor-mediated Ca2+ influx	13
Regulation of the regulator: Endopeptidase cleavage controls the expression of a micropeptide that regulates SERCA.	13
Editorial Board	13
Activation of transient receptor potential vanilloid 4 exacerbates myocardial ischemia-reperfusion injury via JNK-CaMKII phosphorylation pathway in isolated mice hearts	12
Barriers to exocytotic vesicle discharge	11
Channeling hope for uranium-induced kidney damage and beyond with TRPML1	11
Changing of the guards while steering a familiar course	11
Unveiling the intricate role of S100A1 in regulating RyR1 activity: A commentary on “Structural insights into the regulation of RyR1 by S100A1”	11
Neuronal and astrocyte NCX isoform/splice variants: How do they participate in Na+ and Ca2+ signalling?	11
STIM1: The lord of the rings?	11
Scaling up neuronal Ca2+, signaling on ER ladders	11
The evolution of organellar calcium mapping technologies	11

High-throughput assessment identifying major platelet Ca2+ entry pathways via tyrosine kinase-linked and G protein-coupled receptors	11
Editorial Board	11
Regulation of K+-dependent Na+/Ca2+-exchanger subtype 4, NCKX4, by palmitoylation	11
Altered composition of the mitochondrial Ca2+uniporter in the failing human heart	10
Editorial Board	10
Modulators of TRPM7 and its potential as a drug target for brain tumours	10
ELD607 specifically traffics Orai1 to the lysosome leading to inhibition of store operated calcium entry	10
Calcium influx into astrocytes plays a pivotal role in inflammation-driven behaviors	10
Lysosomal potassium channels	10
A KRAP(y) job: Defining the localization of active IP3R	10
Handling a mature calcium signature through optogenetics improves the differentiation of primary murine myotubes	10
Structural snapshots of the mechanism of TRPV2 channel activation by small-molecule agonists	10
Calcium signalling in hepatic metabolism: Health and diseases	9
Inhibition of TRPV1 by an antagonist in clinical trials is dependent on cholesterol binding	9
Pan-cancer analysis reveals the prognostic gene CASR suppresses tumor progression and epithelial–mesenchymal transition in renal clear cell carcinoma	9
Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7	9
SERCA2 phosphorylation at the heart of the disease	9
TRPV2 inhibitor tranilast prevents atrial fibrillation in rat models of pulmonary hypertension	9
Calcium and chloride out of sync: The role of signaling in Sjögren's salivary gland issues	9
Copine A is essential for calcium homeostasis in Dictyostelium	9
Multi-neurotransmitter regulation of neural firing via coincidence of parallel G-protein signals	9
Toll-like receptor 4 activation enhances Orai1-mediated calcium signal promoting cytokine production in spinal astrocytes.	9
Distinct pools of synaptic vesicles are released by different calcium channels	9
Engulf and digest – TRPM7 as key regulator of macrophage phagosome maturation	9
Orai1/STIMs modulators in pulmonary vascular diseases	9
Trace metals and astrocytes physiology and pathophysiology	8
Interstitial cell of Cajal-like cells (ICC-LC) exhibit dynamic spontaneous activity but are not functionally innervated in mouse urethra	8
Rhomboid pseudoproteases: An Achilles heel's for BCL-2/IP3R-dependent resistance to ER stress-induced cell death	8
Endogenous insulin directly protects pancreatic acinar cells in pancreatitis	8
Unravelling the complexity of the mitochondrial Ca2+ uniporter: regulation, tissue specificity, and physiological implications	8
Uncovering a new route to pain therapy	8
Conjugated polymers mediate intracellular Ca2+ signals in circulating endothelial colony forming cells through the reactive oxygen species-dependent activation of Transient Receptor Potential Vanilloi	8
Sodium homeostasis and signalling: The core and the hub of astrocyte function	8
The ryanodine receptor microdomain in cardiomyocytes	8
“Functional communication between IP3R and STIM2 at subthreshold stimuli is a critical checkpoint for initiation of SOCE”	8
Pharmacological agents selectively acting on the channel moieties of TRPM6 and TRPM7	8
Emergence of repurposed drugs as modulators of MCU channel for clinical therapeutics	8
Coordinated glucose-induced Ca2+ and pH responses in yeast Saccharomyces cerevisiae	8
Astrocytic chloride regulates brain function in health and disease	8
Shocking insights for neurovascular coupling: Electrical signals ignite calcium dynamics in brain capillaries	8
The dynamic TRPV2 ion channel proximity proteome reveals functional links of calcium flux with cellular adhesion factors NCAM and L1CAM in neurite outgrowth	8
CatSper channels in sea urchin sperm	8
Anoctamin 1, a multi-modal player in pain and itch	7
Modulation of carbachol-induced Ca2+ oscillations in airway smooth muscle cells by PGE2	7
The STIM1 Phosphorylation Saga	7
Viewing Ca2+-binding sites in the inositol trisphosphate receptor	7
The unfolding and activation of STIM1 in store-operated calcium signal generation	7
Editorial Board	7
Recognition of granulocyte-macrophage colony-stimulating factor by specific S100 proteins	7
Anoctamin pharmacology	6
Excitatory cholinergic responses in mouse primary bronchial smooth muscle require both Ca2+ entry via l-type Ca2+ channels and store operated Ca2+ entry via Orai channels	6
TRPC3, an underestimated, universal pacemaker channel?	6
VDAC2 as a novel target for heart failure: Ca2+ at the sarcomere, mitochondria and SR	6
PI(3,5)P2 and NAADP: Team players or lone warriors? – New insights into TPC activation modes	6
Neurophysiological functions and pharmacological tools of acidic and non-acidic Ca2+ stores	6
Corrigendum to “Mutations and clinical significance of calcium voltage-gated channel subunit alpha 1E (CACNA1E) in non-small cell lung cancer” [Cell Calcium 102 (2022) 102527]	6
Calcium sequestration by human platelet acidic organelles is regulated by the actin cytoskeleton and autocrine 5-hydroxytryptamine	6
Control of STIM and Orai function by post-translational modifications	6
Editorial Board	6
Remodeling Ca2+ dynamics by targeting a promising E-box containing G-quadruplex at ORAI1 promoter in triple-negative breast cancer	6
Is CD38 involved in Ca2+ signalling elicited by activation of T cell receptors?	5
Editorial Board	5
TRPV4 and the paradox of faster cellular migration rates in more viscous extracellular fluids	5
CaV1.3 enhanced store operated calcium promotes resistance to androgen deprivation in prostate cancer	5
Editorial Board	5
Pivotal role of the ORAI3-STIM2 complex in the control of mitotic death and prostate cancer cell cycle progression	5
Polarity of action in salivary gland acinar cells: Local and preferential Ca2+ signalling	5
Exploring the Li+ transporting mutant of NCX_Mj for assigning ion binding sites of mitochondrial NCLX	5
The role of Ca2+-signaling in the regulation of epigenetic mechanisms	5
Enhanced myofilament calcium sensitivity aggravates abnormal calcium handling and diastolic dysfunction in patient-specific induced pluripotent stem cell-derived cardiomyocytes with MYH7 mutation	5
The physiological roles of anoctamin2/TMEM16B and anoctamin1/TMEM16A in chemical senses	5
Oncomodulin (OCM) uniquely regulates calcium signaling in neonatal cochlear outer hair cells	5
Editorial Board	5
T-type channels in cancer cells: Driving in reverse	5
Periphery Pre-S1 and S1 helix nexus for PIP2 at TRPC3 channel	5
Human IP3 receptor triple knockout stem cells remain pluripotent despite altered mitochondrial metabolism	5
Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures	5
WNK kinase, ion channels and arachidonic acid metabolites choreographically execute endothelium-dependent vasodilation	5
NAADP receptors: A one-two.	5
Epithelial Anoctamins	4

Editorial Board	4
Genomic approachesidentifySTT4 as a new component in glucose-induced activation of yeast plasma membrane H+-ATPase	4
Decline of astrocyte Ca2+ signalling in Alzheimer's disease: STIM1 to the rescue!	4
IP3-dependent Ca2+ signals are tightly controlled by Cavβ3, but not by Cavβ1, 2 and 4	4
SERCA-1 conformational change exerted by the Ca2+-channel blocker diltiazem affects mammalian skeletal muscle function	4
Two-pore channels (TPCs) acts as a hub for excitation-contraction coupling, metabolism and cardiac hypertrophy signalling	4
Editorial Board	4
Boosting ER-mitochondria calcium transfer to treat Wolfram syndrome	4
Development of chemical tools based on GSK-7975A to study store-operated calcium entry in cells	4
Editorial Board	4
Ionic signalling (beyond calcium) in the nervous system: Physiology and pathophysiology	4
The Mitochondrial Ca2+ import complex is altered in ADPKD	4
Editorial Board	4
The many facets of TMEM63/OCaR proteins as mechanosensitive channels in lysosomes, NAADP signaling and beyond	4
Calcium acts as a critical determinant of mitochondria-nuclear networking driven retrograde signaling	4
TREM2 and calcium signaling in microglia – is it relevant for Alzheimer's disease?	3
Homeostatic calcium fluxes, ER calcium release, SOCE, and calcium oscillations in cultured astrocytes are interlinked by a small calcium toolkit	3
Regulation and role of calcium in cellular senescence	3
Roles for TRPV4 in disease: A discussion of possible mechanisms	3
Ca2+ transport via TRPV6 is regulated by rapid internalization of the channel	3
RyR-ing up nuclear calcium signaling and CREB-mediated gene expression	3
Tubular aggregate myopathy mutant unveils novel activation and inactivation mechanisms of Orai1	3
The A-kinase anchoring protein Yotiao decrease the ER calcium content by inhibiting the store operated calcium entry	3
TRPMLs and TPCs: Targets for lysosomal storage and neurodegenerative disease therapy?	3
Above the legal limit: Alcohol brings ER and mitochondria too close together	3
The interplay between associated proteins, redox state and Ca2+ in the intraluminal ER compartment regulates the IP3 receptor	3
Fine tuning calcium dynamics by inhibition of Store-operated Calcium Entry as a novel therapeutic approach for the treatment of chronic pancreatitis	3
CRACing the role of calcium signaling in ILC2s	3
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration	3
Vesicle cholesterol controls exocytotic fusion pore	3
Nanojunctions: Specificity of Ca2+ signaling requires nano-scale architecture of intracellular membrane contact sites	3
Anoctamins in epithelial transport	3
Calcium and redox signals at mitochondrial interfaces: A nanoview perspective	3
All-optical mapping of Ca2+ transport and homeostasis in dendrites	3
Full-fusion and kiss-and-run in chromaffin cells controlled by irreversible vesicle size-dependent fusion pore transitions	3
Ca2+ signaling and cell death	2
NAADP signaling: Master manipulation	2
A deep learning-based approach for efficient detection and classification of local Ca²⁺ release events in Full-Frame confocal imaging	2
Diversity of two-pore channels and the accessory NAADP receptors in intracellular Ca2+ signaling	2
Title: Jealous protons sour another happy marriage; the story of how TRPV5 and PI(4,5)P2 split up.	2
PUFAs dictate the balance of power in ferroptosis	2
Editorial Board	2
MLKL overexpression leads to Ca2+ and metabolic dyshomeostasis in a neuronal cell model	2
Editorial Board	2
Calcium signaling in lysosome-dependent cell death	2
The role of Ca2+ signalling in the pathology of exocrine pancreas	2
A TRPV6 expression atlas for the mouse	2
Stable expression of SARS-CoV-2 envelope viroporin promotes intracellular calcium depletion in human cells: relevance for endoplasmic reticulum stress, cell proliferation, pluripotency and lineage dif	2
Orai1/KCa/SigmaR1 complex, the cancer cell suicide squad	2
You better keep an eye on your contacts	2
GPR30 is a potential player between islet cells and ductal HCO3− secretion	2
“Gatekeepers of heaven” breaking bad	2
Subcellular localization and transcriptional regulation of brain ryanodine receptors. Functional implications	2
Campari2 genomic interrogation of homeostatic calcium activity identifies TIM1 as a negative regulator of T cell function	2
TRPC1: The housekeeper of the hippocampus	2
IN BRAIN POST-ISCHEMIC PLASTICITY, Na+/Ca2+ EXCHANGER 1 AND Ascl1 INTERVENE IN MICROGLIA-DEPENDENT CONVERSION OF ASTROCYTES INTO NEURONAL LINEAGE	2
Is Zn2+ the new Ca2+ for TRPC6 channels in the myocardium?	2
STIM1 is the key that unlocks airway smooth muscle remodeling and hyperresponsiveness during asthma	2
The quest to map STIM1 activation in granular detail	2
Dimming the donor to brighten up FRET-based biosensors	2
In vitro and in vivo calibration of low affinity genetic Ca2+ indicators	2