Cell Calcium

Article	Citations
Regulating calcium flux through AMPA glutamate receptors	81
Commentary on: Li et al.; Ca2+ transients on the T cell surface trigger rapid integrin activation in a timescale of seconds. Nature Communications (2024)	76
Store-operated ion channels: A growing family ?	75
Rapid Quantification of First and Second Phase Insulin Secretion Dynamics using an In vitro Platform for Improving Insulin Therapy	64
Arriving at the next level of complexity in IP3R and SOCE signaling	55
TRPM7 in neurodevelopment and therapeutic prospects for neurodegenerative disease	54
Protein diversity in store-operated calcium entry components and their related variants	41
Rapid quantification of intracellular calcium stores reveals effects of membrane micropeptides on SERCA function	38
ER calcium stores contribute to glucose-induced Ca2+ waves and intercellular connectivity in mouse pancreatic islets	38
Calmodulin inhibitors chlorpromazine and calmidazolium cause calcium overload and oxidative stress despite reducing peak density of CaV1.2 current in ventricular myocytes	36
Editorial Board	35
The IP3 receptor-KRAP complex at the desmosomes: A new player in the apoptotic process	32
Abnormal calcium activity and CREB phosphorylation are associated with motor memory impairment in presenilin-1 mutant knock-in mice	28
STIM1: A new player in nuclear dynamics? Lessons learnt from tubular aggregate myopathy	28
MICU1 and MICU2, two peas in a pod or entirely different fruits?	27
A role for lysosomal calcium channels in mitigating mitochondrial damage and oxidative stress	26
Calcium signals as regulators of ferroptosis in cancer	24
TRPC3 governs the spatiotemporal organization of cellular Ca2+ signatures by functional coupling to IP3 receptors	24
Macrophage migration inhibitory factor induces phospholamban phosphorylation in cardiac muscle	23
Editorial Board	22
Role of auditory-somatosensory corticothalamic circuit integration in analgesia	22
PIP2 primes IP3 receptor activity: It takes at least three IP3s to open!	22
STIMulating IRE1: How store-operated Ca2+ entry intersects with ER proteostasis	22
NAADP-mediated calcium release promotes angiopoietin 2 secretion by regulating Rab46-dependent Weibel-Palade body trafficking	21
Ca2+/calmodulin-driven functions mediated by extracellular vesicles: a physiopathological perspective	21

Histamine 1 receptors and reverse-mode Na+/Ca2+ exchanger drive extracellular Na+-dependent intracellular Ca2+ oscillations in human cerebrovascular endothelial cells	21
Neuronal regulation of myenteric interstitial cells of Cajal (ICC-MY) in the proximal colon	21
Optical profiling of autonomous Ca2+ nanodomains generated by lysosomal TPC2 and TRPML1	20
Editorial Board	19
Editorial Board	19
High resolution cryo-EM structures of TRPC5-Gαi3 complexes reveal direct activation of an ion channel by Gαi-GTP	18
Editorial Board	18
Editorial Board	17
TRPV1 signaling in skeletal muscle: A mini review of physiological and pathological roles	17
The tether function of the anoctamins	17
Intersection between calcium signalling and epithelial-mesenchymal plasticity in the context of cancer	17
IP3 receptors: An “elementary” journey from structure to signals	16
Editorial Board	16
The role of SERCA in vascular diseases, a potential therapeutic target	16
Endoplasmic reticulum-mitochondria lockdown in Wolfram syndrome	15
The PHATE of basal epidermal cells: Calcium signaling during the cell cycle	15
GPCR signalling: Yet another variant route in a highly complex road map	15
Simultaneous TIRF imaging of subplasmalemmal Ca2+ dynamics and granule fusions in insulin-secreting INS-1 cells reveals coexistent synchronized and asynchronous release	14
Transcriptional, biochemical, and immunohistochemical analyses of CaMKKβ/2 splice variants that co-localize with CaMKIV in spermatids	14
Editorial Board	14
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The emerging role of TRPV4 in skeletal biology: Mechanotransduction, mutation, and therapeutic potential	13
Editorial Board	13
Pseudomonas aeruginosa 3-oxo-C12HSL-induced apoptosis involves bitter taste receptor T2R14 and the mitochondrial calcium uniporter	13
Editorial Board	12
STIM1: The lord of the rings?	12
Barriers to exocytotic vesicle discharge	12
The evolution of organellar calcium mapping technologies	12
High-throughput assessment identifying major platelet Ca2+ entry pathways via tyrosine kinase-linked and G protein-coupled receptors	11
CPVT1 point mutations in RyR2 S5 and S6 segments and their Ca2+ signaling consequence	11
Regulation of the regulator: Endopeptidase cleavage controls the expression of a micropeptide that regulates SERCA.	11
Neuronal and astrocyte NCX isoform/splice variants: How do they participate in Na+ and Ca2+ signalling?	10
Editorial Board	10
Unveiling the intricate role of S100A1 in regulating RyR1 activity: A commentary on “Structural insights into the regulation of RyR1 by S100A1”	10
Orai1 mediates ICRAC and SOCE in human placental extravillous trophoblasts and contributes to cell viability, migration, and invasion	10
Changing of the guards while steering a familiar course	10
Calcium signaling and genetic rare diseases: An auditory perspective	10
A NOX2-independent mechanism of Hv1 channel activation promotes inflammatory cytokine release from BV-2 microglia via intracellular Ca2+ mobilisation	10
TRPV2 inhibitor tranilast prevents atrial fibrillation in rat models of pulmonary hypertension	10
Scaling up neuronal Ca2+, signaling on ER ladders	9
Connexin 43 as a novel Ca2+ transport pathway in the nuclear envelope of human induced pluripotent stem cell derived cardiomyocytes	9
Irene Schulz and IP3	9
Calcium influx into astrocytes plays a pivotal role in inflammation-driven behaviors	9
Transglutaminase 2 controls calcium dependent mitochondrial dysfunction and fibroblast senescence by repressing PIEZO2	9
Ablation of mitochondrial calcium uniporter alleviates cardiac dysfunction in type 1 diabetes	9
Regulation of K+-dependent Na+/Ca2+-exchanger subtype 4, NCKX4, by palmitoylation	9
Channeling hope for uranium-induced kidney damage and beyond with TRPML1	9
ELD607 specifically traffics Orai1 to the lysosome leading to inhibition of store operated calcium entry	9
Calcium signalling in hepatic metabolism: Health and diseases	9
High-throughput quantitation of pathogen-induced calcium signals captured through live-cell fluorescence microscopy	8

Distinct pools of synaptic vesicles are released by different calcium channels	8
SERCA2 phosphorylation at the heart of the disease	8
Calcium and chloride out of sync: The role of signaling in Sjögren's salivary gland issues	8
Editorial Board	8
Orai1/STIMs modulators in pulmonary vascular diseases	7
Copine A is essential for calcium homeostasis in Dictyostelium	7
In memoriam: Irene Schulz 1941 – 2026	7
Pan-cancer analysis reveals the prognostic gene CASR suppresses tumor progression and epithelial–mesenchymal transition in renal clear cell carcinoma	7
LETM1 and mitochondrial calcium homeostasis: A controversial but critical role in cellular function and disease	7
Shocking insights for neurovascular coupling: Electrical signals ignite calcium dynamics in brain capillaries	7
Engulf and digest – TRPM7 as key regulator of macrophage phagosome maturation	7
Inhibition of TRPV1 by an antagonist in clinical trials is dependent on cholesterol binding	7
Uncovering a new route to pain therapy	7
Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7	7
Pharmacological agents selectively acting on the channel moieties of TRPM6 and TRPM7	6
Unravelling the complexity of the mitochondrial Ca2+ uniporter: regulation, tissue specificity, and physiological implications	6
Corrigendum to: Ca2+/calmodulin-driven functions mediated by extracellular vesicles: a physiopathological perspective	6
Trace metals and astrocytes physiology and pathophysiology	6
Viewing Ca2+-binding sites in the inositol trisphosphate receptor	6
CNO induced Ca2+ store and glutamate-dependent nonspecific Ca2+ signalling in DREADD-free brain slices	6
Interstitial cell of Cajal-like cells (ICC-LC) exhibit dynamic spontaneous activity but are not functionally innervated in mouse urethra	6
The handshake between the continuous remodeling of the endoplasmic reticulum and the store-operated calcium entry	6
Emerging therapeutics targeting the PI3K/Akt/GSK-3β in calcium dysregulation in Alzheimer’s disease	6
Sodium homeostasis and signalling: The core and the hub of astrocyte function	6
The dynamic TRPV2 ion channel proximity proteome reveals functional links of calcium flux with cellular adhesion factors NCAM and L1CAM in neurite outgrowth	6
The ryanodine receptor microdomain in cardiomyocytes	6
Anoctamin 1, a multi-modal player in pain and itch	6
Astrocytic chloride regulates brain function in health and disease	6
Recognition of granulocyte-macrophage colony-stimulating factor by specific S100 proteins	5
TRPV4 and the paradox of faster cellular migration rates in more viscous extracellular fluids	5
Corrigendum to “Mutations and clinical significance of calcium voltage-gated channel subunit alpha 1E (CACNA1E) in non-small cell lung cancer” [Cell Calcium 102 (2022) 102527]	5
Excitatory cholinergic responses in mouse primary bronchial smooth muscle require both Ca2+ entry via l-type Ca2+ channels and store operated Ca2+ entry via Orai channels	5
Remodeling Ca2+ dynamics by targeting a promising E-box containing G-quadruplex at ORAI1 promoter in triple-negative breast cancer	5
WNK kinase, ion channels and arachidonic acid metabolites choreographically execute endothelium-dependent vasodilation	5
PI(3,5)P2 and NAADP: Team players or lone warriors? – New insights into TPC activation modes	5
Anoctamin pharmacology	5
Human IP3 receptor triple knockout stem cells remain pluripotent despite altered mitochondrial metabolism	5
Nuclear Ca2+-Calmodulin signaling in cardiac myocytes reduces catecholamine-evoked protein translation and prevents hypertrophy	5
Exploring the Li+ transporting mutant of NCX_Mj for assigning ion binding sites of mitochondrial NCLX	4
Molecular actors of the Calcium signaling in the endothelial-to-mesenchymal transition: poorly explored therapeutic targets	4
Editorial Board	4
Editorial Board	4
Pivotal role of the ORAI3-STIM2 complex in the control of mitotic death and prostate cancer cell cycle progression	4
Enhanced myofilament calcium sensitivity aggravates abnormal calcium handling and diastolic dysfunction in patient-specific induced pluripotent stem cell-derived cardiomyocytes with MYH7 mutation	4
Pathological calcium influx through amyloid beta pores disrupts synaptic function	4
Fura-10, unlike fura-2, is suitable for long-term calcium imaging in natural killer (NK) cells without compromising cytotoxicity and can be combined with target cell death analysis	4
The physiological roles of anoctamin2/TMEM16B and anoctamin1/TMEM16A in chemical senses	4
Periphery Pre-S1 and S1 helix nexus for PIP2 at TRPC3 channel	4
The role of Ca2+-signaling in the regulation of epigenetic mechanisms	4
Editorial Board	4
Genomic approachesidentifySTT4 as a new component in glucose-induced activation of yeast plasma membrane H+-ATPase	3
Editorial Board	3
The many facets of TMEM63/OCaR proteins as mechanosensitive channels in lysosomes, NAADP signaling and beyond	3
Pharmacological modulation of TRPV2 enhances migration and induces Immunoglobulin E (IgE)-independent degranulation of mast cells	3
Above the legal limit: Alcohol brings ER and mitochondria too close together	3
Calcium acts as a critical determinant of mitochondria-nuclear networking driven retrograde signaling	3
Editorial Board	3
Decline of astrocyte Ca2+ signalling in Alzheimer's disease: STIM1 to the rescue!	3
Epithelial Anoctamins	3
Development of chemical tools based on GSK-7975A to study store-operated calcium entry in cells	3
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration	3
Two-pore channels (TPCs) acts as a hub for excitation-contraction coupling, metabolism and cardiac hypertrophy signalling	3
SERCA-1 conformational change exerted by the Ca2+-channel blocker diltiazem affects mammalian skeletal muscle function	3
Ionic signalling (beyond calcium) in the nervous system: Physiology and pathophysiology	3
CRACing the role of calcium signaling in ILC2s	3
Editorial Board	3
Anoctamins in epithelial transport	3
The dual role of transient receptor potential melastatin cation channels in sepsis	2
Fine tuning calcium dynamics by inhibition of Store-operated Calcium Entry as a novel therapeutic approach for the treatment of chronic pancreatitis	2
“Gatekeepers of heaven” breaking bad	2
A model for the complete sequence of the human voltage-gated calcium channel (CaV1.2) in a lipid bilayer	2
Ca2+ transport via TRPV6 is regulated by rapid internalization of the channel	2
Tubular aggregate myopathy mutant unveils novel activation and inactivation mechanisms of Orai1	2
The interplay between associated proteins, redox state and Ca2+ in the intraluminal ER compartment regulates the IP3 receptor	2
The role of Ca2+ signalling in the pathology of exocrine pancreas	2
In vitro and in vivo calibration of low affinity genetic Ca2+ indicators	2
The quest to map STIM1 activation in granular detail	2
Ca2+ signaling and cell death	2
TRPC1: The housekeeper of the hippocampus	2
Subcellular localization and transcriptional regulation of brain ryanodine receptors. Functional implications	2

All-optical mapping of Ca2+ transport and homeostasis in dendrites	2
Campari2 genomic interrogation of homeostatic calcium activity identifies TIM1 as a negative regulator of T cell function	2
Nanojunctions: Specificity of Ca2+ signaling requires nano-scale architecture of intracellular membrane contact sites	2
Isoform-specific structure and function of calsequestrin: Implications beyond calcium buffering in health and disease	2
Regulation and role of calcium in cellular senescence	2
The A-kinase anchoring protein Yotiao decrease the ER calcium content by inhibiting the store operated calcium entry	2
A deep learning-based approach for efficient detection and classification of local Ca²⁺ release events in Full-Frame confocal imaging	2
Stable expression of SARS-CoV-2 envelope viroporin promotes intracellular calcium depletion in human cells: relevance for endoplasmic reticulum stress, cell proliferation, pluripotency and lineage dif	2
Is Zn2+ the new Ca2+ for TRPC6 channels in the myocardium?	2
Orai1 plays a critical role in Orai3 synthesis and stability in luminal breast cancer cells	2
Endothelial PIEZO1 activation impairs osteogenesis via GREM1-mediated inhibition of BMP signaling	2
MLKL overexpression leads to Ca2+ and metabolic dyshomeostasis in a neuronal cell model	2
In memoriam: Irene Schulz-Hofer	2
Calcium signaling in lysosome-dependent cell death	2
Spatially multiplexed stimulation reveals nonlinear calcium signaling in platelets	2
Roles for TRPV4 in disease: A discussion of possible mechanisms	2
NAADP signaling: Master manipulation	2
You better keep an eye on your contacts	2
GPR30 is a potential player between islet cells and ductal HCO3− secretion	2
Editorial Board	2
Editorial Board	2