OOIR: Observatory of International Research

Papers

(The median citation count of Neuropeptides is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Modulation of temporoammonic-CA1 synapses by neuropeptide Y is through Y1 receptors in mice	43
Regional differences of tachykinin effects on smooth muscle and pacemaker potentials of the stomach, duodenum, ileum and colon of an emetic model, the house musk shrews	28
Editorial Board	27
Emerging functions of neuronostatin in physiology, pathology, and potential therapeutics	23
Baroreflex afferent function is a part of insights of Leptin-mediated blood pressure reduction and Leptin-resistance hypertension	23
Editorial Board	22
Restraint stress potentiates sensitivity to the antinociceptive effect of morphine through orexin receptors in the ventral tegmental area	21
Editorial Board	19
The relationship between brain-derived neurotrophic factor and metabolic syndrome in patients with chronic schizophrenia: A systematic review	19
Editorial Board	18
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Editorial Board	17
Amylin regulates testosterone levels via steroidogenesis-related enzymes in the central nervous system of male mice	17
A retrospective study on the efficacy of Ninjin’yoeito on fatigue in patients with interstitial pneumonia	16
Changes in ghrelin, substance P and vasoactive intestinal peptide levels in the gastroduodenal mucosa of patients with morbid obesity	15
Neurocircuitry underlying the actions of glucagon-like peptide 1 and peptide YY3–36 in the suppression of food, drug-seeking, and anxiogenesis	15
Potentiation of microglial endocannabinoid signaling alleviates neuroinflammation in Alzheimer's disease	14
Pharmacological profile of agmatine: An in-depth overview	14
hucMSCs transplantation promotes locomotor function recovery, reduces apoptosis and inhibits demyelination after SCI in rats	13
Localization of neuropeptide receptor NPY4R in rat retina	13
Opioid growth factor receptor: Anatomical distribution and receptor colocalization in neurons of the adult mouse brain	13
HLDF-6 peptides exhibit neuroprotective effects in the experimental model of preclinical Parkinson's disease	11
Thyrotropin-releasing hormone induces Ca2+ increase in a subset of vagal nodose ganglion neurons	11
Expression of immune-related proteins and their association with neuropeptides in adolescent patients with anorexia nervosa	11
Medicine and food with particular reference to chinpi, dried citrus peel, and a component of Ninjin'yoeito	11

Exercise modulates APOE expression in brain cortex of female APOE3 and APOE4 targeted replacement mice	10
Apelin receptor antagonist (ML221) treatment has a stimulatory effect on the testicular proliferation, antioxidants system and steroidogenesis in adult mice	10
NK1 receptor blockade disrupts microtumor growth and aggregation in a three-dimensional murine breast cancer model	10
Intravenous administration of xenin-25 accelerates cyclic ruminal contractions in healthy conscious sheep	10
Synergistic effects of hIAPP and Aβ1–42 impaired the olfactory function associated with the decline of adult neurogenesis in SVZ	10
Ninjinyoeito ameliorates anorexia and changes in peptide YY and ghrelin levels of cisplatin-treated mice	10
The stress-induced antinociceptive responses to the persistent inflammatory pain involve the orexin receptors in the nucleus accumbens	10
Enteroendocrine cell-derived peptide YY signalling is stimulated by pinolenic acid or Intralipid and involves coactivation of fatty acid receptors FFA1, FFA4 and GPR119	10
Bromelain decreases oxidative stress and Neuroinflammation and improves motor function in adult male rats with cerebellar Ataxia induced by 3-acetylpyridine	9
Sex-dimorphic hindbrain lactate regulation of ventromedial hypothalamic nucleus glucoregulatory neuron 5’-AMP-activated protein kinase activity and transmitter marker protein expression	9
Protective effects of Zishen Huoxue recipe against neuronal injury in the neurovascular unit of rats with vascular dementia by interfering with inflammatory cascade-induced pyroptosis	9
Adrenomedullin-mediated depressor response with visceral afferent-specific membrane depolarization in isolated nodose ganglion neurons from adult female rat	8
Neuroanatomical mapping of spexin and nesfatin-1-expressing neurons in the human brainstem	8
Combination therapy with neuropeptides for the treatment of anxiety disorder	8
Protective effect of TNIP2 on the inflammatory response of microglia after spinal cord injury in rats	8
Editorial Board	8
CDNF overexpression prevents motor-cognitive dysfunction by intrastriatal CPP-based delivery system in a Parkinson's disease animal model	7
The effects of neurosteroid allopregnanolone on synaptic dysfunction in the hippocampus in experimental parkinsonism rats: An electrophysiological and molecular study	7
Corrigendum to “Survey of problems in Kampo curriculum and the need for interdisciplinary collaboration education in Japanese medical, pharmacy, dental, and nursing departments” [Neuropeptides 92 (202	7
Neuropeptides as regulators of the hypothalamus-pituitary-gonadal (HPG) axis activity and their putative roles in stress-induced fertility disorders	7
WITHDRAWN: CircBUB1 activates the PI3K/AKT signaling pathway to promote the migration and invasion of glioblastoma cells	7
A recent update on drugs and alternative approaches for parkinsonism	6
Bezafibrate protects blood-brain barrier (BBB) integrity against traumatic brain injury mediated by AMPK	6
Expression of phoenixin-14 and nesfatin-1 in the hypothalamo–pituitary–gonadal axis in the phases of the estrous cycle	6
The management and metabolic characterization: hyperthyroidism and hypothyroidism	6
Neuropeptide Y Y2 receptors in acute and chronic pain and itch	6
Benincasa hispida alleviates amyloid pathology by inhibition of Keap1/Nrf2-axis: Emphasis on oxidative and inflammatory stress involved in Alzheimer's disease model	6
Research progress on the protection and mechanism of active peptides in Alzheimer's disease and Parkinson's disease	6
Hippocampal orexin-1 and endocannabinoid-1 receptors underlie the kainate-induced occlusion in theta-burst long- term potentiation	6
Editorial Board	6
The bee venom active compound melittin protects against bicuculline-induced seizures and hippocampal astrocyte activation in rats	6
Cyclooxygenase-2 inhibition affects the ratio of GluN2A/GluN2B receptor subunits through interaction with mGluR5 in the mouse brain	6
Interactions between the regulatory peptide 26RFa (QRFP) and insulin in the regulation of glucose homeostasis in two complementary models: The high fat 26RFa-deficient mice and the streptozotocin insu	6
Effects of intracerebroventricular and intravenous administration of Kisspeptin-54 and Gonadotropin-releasing hormone agonist in rats with ovarian hyperstimulation	6
Effects of substance P on human cerebral microvascular endothelial cell line hCMEC/D3 are mediated exclusively through a truncated NK-1 receptor and depend on cell confluence	6
Editorial Board	5
Tetrahydroxy stilbene glycoside regulates TGF-β/fractalkine/CX3CR1 based on network pharmacology in APP/PS1 mouse model	5
Peripheral apelin mediates visceral hypersensitivity and impaired gut barrier in a rat irritable bowel syndrome model	5
Sucralose uses reward pathways to promote acute caloric intake	5
Age-dependent change of RFRP-3 neuron numbers and innervation in female mice	5
The regulatory effects of the apelin/APJ system on depression: A prospective therapeutic target	5
Evaluating the usefulness of Ninjin'yoeito Kampo medicine in combination with rehabilitation therapy in patients with frailty complicated by intractable dizziness	5
Transcranial pulsed current stimulation alleviates neuronal pyroptosis and neurological dysfunction following traumatic brain injury via the orexin-A/NLRP3 pathway	5
Omentin and visfatin in adolescent inpatients with anorexia nervosa; association with symptoms	5
Editorial Board	5
The use of intranasal oxytocin in the treatment of eating disorders	5
WITHDRAWN: Age-dependent modulation of RFRP-3 neurons in female mice	5
Mechanistic role of proteins and peptides in Management of Neurodegenerative Disorders	5
Neuropeptide Y and receptors are associated with the pyroptosis of nucleus pulposus in aging and degenerative intervertebral discs of rats	5
Neuritogenesis and protective effects activated by Angiotensin 1–7 in astrocytes-neuron interaction	4

Semax, synthetic ACTH(4–10) analogue, attenuates behavioural and neurochemical alterations following early-life fluvoxamine exposure in white rats	4
A Na+ channel receptor of FMRFamide in the cephalopod Sepiella japonica: Identification, characterisation, and expression profiling during different stages of gonadal development	4
Cocaine and amphetamine regulated transcript peptide (CART) in the tadpole brain: Response to different energy states	4
Neuropeptide FF prevented histamine- or chloroquine-induced acute itch behavior through non-NPFF receptors mechanism in male mice	4
Metformin promotes Schwann cell remyelination, preserves neural tissue and improves functional recovery after spinal cord injury	4
Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models	4
Bee venom ameliorates oxidative stress and histopathological changes of hippocampus, liver and testis during status epileptics	4
Neurotransmitters and Neuropeptides decrease PD-1 in T cells of healthy subjects and patients with hepatocellular carcinoma (HCC), and increase their proliferation and eradication of HCC cells	4
Ninjinyoeito improves anxiety behavior in neuropeptide Y deficient zebrafish	4
MP-13, a novel chimeric peptide of morphiceptin and pepcan-9, produces potent antinociception with limited side effects	4
Cross talk about the role of Neuropeptide Y in CNS disorders and diseases	4
GSK-3β as a target for apigenin-induced neuroprotection against Aβ 25–35 in a rat model of Alzheimer's disease	4
Altered neurotransmission in stress-induced depressive disorders: The underlying role of the amygdala in depression	4
New fraternine analogues: Evaluation of the antiparkinsonian effect in the model of Parkinson's disease	4
Neuropeptide Y modifies a part of diencephalic catecholamine but not indolamine metabolism in chicks depending on feeding status	4
Altered levels of neurobiological biomarkers at the interface of depression and gestational diabetes mellitus in Asian Indian women	4
GnRH protective effects against long-term potentiation impairment induced by AANAT-siRNA	4
4-hydroxyisoleucine mediated IGF-1/GLP-1 signalling activation prevents propionic acid-induced autism-like behavioural phenotypes and neurochemical defects in experimental rats	4
Chemogenetic activation of arcuate nucleus NPY and NPY/AgRP neurons increases feeding behaviour in mice	4
Ninjin'yoeito modulates feeding and activity under negative energy balance conditions via the NPY system	3
The involvement of the central cholinergic system in the hyperventilation effect of centrally injected nesfatin-1 in rats	3
Lipid metabolism: Novel approaches for managing idiopathic epilepsy	3
Ang (1–7)/Mas receptor-axis activation promotes amyloid beta-induced altered mitochondrial bioenergetics in discrete brain regions of Alzheimer's disease-like rats	3
Pyroglutamylated RFamide peptide (QRFP): Role in early testicular development in relation to Sertoli cell maturation in prepubertal mice	3
Protective effect of N-acetyl cysteine on the mitochondrial dynamic imbalance in temporal lobe epilepsy: Possible role of mTOR	3
Ghrelin protects against rotenone-induced cytotoxicity: Involvement of mitophagy and the AMPK/SIRT1/PGC1α pathway	3
Important role of NPY-Y4R signalling in the dual control of feeding and physical activity	3
Ninjin'yoeito, a herbal medicine, enhances glucose tolerance in mice	3
Dissecting the functional significance of HSP90AB1 and other heat shock proteins in countering glioblastomas and ependymomas using omics analysis and drug prediction using virtual screening	3
Arginine vasopressin effects on membrane potentials of preoptic area temperature-sensitive and -insensitive neurons in rat hypothalamic tissue slices	3
Biochemical characterization of Prokineticin 2 binding to Prokineticin receptor 1 in zebrafish	3
Involvement of T-type calcium channels in the mechanism of low dose morphine-induced hyperalgesia in adult male rats	3
Chemokine CXCL10 regulates pain behaviors via PI3K-AKT signaling pathway in mice	3
Physiologically relevant lactate accumulation from exercise or peripheral injection does not alter central or peripheral appetite signaling in mice	3
Role of endothelin in the pathophysiology of migraine: A new view on an old player	3
Neuropeptides or their receptors in pathogenesis of lung diseases and therapeutic potentials	3
Trefoil factor 1 (TFF1) reduces cerebral edema and gastric mucosal injury by regulating the EGFR/Src/FAK pathway in an intracerebral hemorrhage rat model	2
Fat mass and obesity-associated protein regulates RNA methylation associated with spatial cognitive dysfunction after chronic cerebral hypoperfusion	2
Onion component, isoalliin, stimulates feeding and activates the arcuate nucleus neuropeptide Y, ghrelin- and Ninjin'yoeito-responsive neurons	2
Editorial Board	2
Melittin ameliorates motor function and prevents autophagy-induced cell death and astrogliosis in rat models of cerebellar ataxia induced by 3-acetylpyridine	2
Antioxidant PRDX3 gene therapy protects brain cells and prevents neurodegeneration in an animal model of Parkinson's disease	2
Oxytocin as neuro-hormone and neuro-regulator exert neuroprotective properties: A mechanistic graphical review	2
The protective effects of orexin B in neuropathic pain by suppressing inflammatory response	2
The role of cholecystokinin and peptide YY in feed intake in Atlantic halibut (Hippoglossus hippoglossus) larvae	2
Effects of an herbal adaptogen feed-additive on feeding-related hypothalamic neuropeptides in chronic cyclic heat-stressed chickens	2
Editorial Board	2
Hippocampal pituitary adenylate cyclase–activating polypeptide mediates rapid antidepressant-like effects of Yueju pill	2
The effects of corticotropin-releasing factor (CRF) and urocortins on the serotonin (hydroxytryptamine, 5HT) released from the raphe nuclei (RN)	2
Several neuropeptides involved in parkinsonian neuroprotection modulate the firing properties of nigral dopaminergic neurons	2
Central regulatory mechanisms of visceral sensation in response to colonic distension with special reference to brain orexin	2
Ac-SDKP peptide improves functional recovery following spinal cord injury in a preclinical model	2
Editorial Board	2
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The activity of cholinergic neurons in the basal forebrain interferes with anesthesia-arousal process of propofol	2
NPFF signalling is critical for thermosensory and dietary regulation of thermogenesis	2
Regulation of the central melanocortin system on energy balance in mammals and birds	2