OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical Science is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Retraction: BMSC-derived exosomes carrying microRNA-122-5p promote progression of osteoblasts in osteonecrosis of the femoral head	183
Dietary restriction and medical therapy drives PPARα-regulated improvements in early diabetic kidney disease in male rats	166
Harnessing 2D and 3D human endometrial cell culture models to investigate SARS-CoV-2 infection in early pregnancy	166
Aging and sex differences in salt sensitivity of blood pressure	158
Cancer therapy-related cardiac dysfunction: is endothelial dysfunction at the heart of the matter?	147
Novel avenues to control blood pressure: targeting the renal lymphatic system	132
The double sides of NLRP3 inflammasome activation in sepsis	106
Youth versus adult-onset type 2 diabetic kidney disease: Insights into currently known structural differences and the potential underlying mechanisms	104
The importance of placental lipid metabolism across gestation in obese and non-obese pregnancies	72
Interactions between cardiology and oncology drugs in precision cardio-oncology	68
Measuring muscle protein synthesis in humans and the influence of nutritional state	62
Increased angiotensin II formation in the brain modulates cardiovascular homeostasis and erythropoiesis	51
Sex differences in angiotensin II-induced hypertension and kidney injury: role of AT1a receptors in the proximal tubule of the kidney	49
Arrb2 causes hepatic lipid metabolism disorder via AMPK pathway based on metabolomics in alcoholic fatty liver	47
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability	46
The science of science: Clinical Science launches a new translational meta-research collection	46
G-protein-coupled receptor kinase 4 causes renal angiotensin II type 2 receptor dysfunction by increasing its phosphorylation	44
Visualization of regenerating and repairing hearts	44
Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of CaV1.2 calcium channel in hypertension	39
Extracellular vesicle-mediated targeting strategies for long-term health benefits in gestational diabetes	38
Regulation of Na+-K+-ATPase leads to disturbances of isoproterenol-induced cardiac dysfunction via interference of Ca2+-dependent cardiac metabolism	38
PE (0:0/14:0), an endogenous metabolite of the gut microbiota, exerts protective effects against sepsis-induced intestinal injury by modulating the AHR/CYP1A1 pathway	38
miR-486-5p protects against rat ischemic kidney injury and prevents the transition to chronic kidney disease and vascular dysfunction	37
Physiological response to fetal intravenous lipid emulsion	35
Maintaining energy provision in the heart: the creatine kinase system in ischaemia–reperfusion injury and chronic heart failure	35

Importance of the gut microbiota in mice with a ‘humanized’ bile acid pool	34
Is endothelin targeting finally ready for prime time?	33
PDCD10 promotes the tumor-supporting functions of TGF-β in pancreatic cancer	33
New discoveries in bile acids, gut microbiota and host interactions in health and diseases	32
Endothelin-1 down-regulates nuclear factor erythroid 2-related factor-2 and contributes to perivascular adipose tissue dysfunction in obesity	32
Paradoxical effects of osteoprotegerin on vascular function: inhibiting inflammation while promoting oxidative stress?	32
CXCL5 inhibition ameliorates acute kidney injury and prevents the progression from acute kidney injury to chronic kidney disease	32