OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical Science is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)

Article	Citations
α-Adrenergic blockade prevented environmental temperature reduction-induced transient portal pressure surge in cirrhotic and portal hypertensive rats	252
Expression of Concern: Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression	198
Maintaining energy provision in the heart: the creatine kinase system in ischaemia–reperfusion injury and chronic heart failure	192
Paradoxical effects of osteoprotegerin on vascular function: inhibiting inflammation while promoting oxidative stress?	186
Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of CaV1.2 calcium channel in hypertension	151
Measuring muscle protein synthesis in humans and the influence of nutritional state	126
The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models	109
Severe psychiatric disorders and general medical comorbidities: inflammation-related mechanisms and therapeutic opportunities	78
Effect of metformin in a novel experimental model of peripheral artery disease	66
Metal regulation of Mycobacterium tuberculosis SufB intein splicing at the host–pathogen crossroad	56
Higher circulating ACE2 and DPP3 but reduced ACE and angiotensinogen in hyperreninemic sepsis patients	54
Novel preventive effect of isorhamnetin on electrical and structural remodeling in atrial fibrillation	54
Cardiovascular research at the Heart of Clinical Science	50
Transcriptome-based exploration of potential molecular targets and mechanisms of selenomethionine in alleviating renal ischemia–reperfusion injury	49
CEACAM5 inhibits the lymphatic metastasis of head and neck squamous cell carcinoma by regulating epithelial–mesenchymal transition via inhibiting MDM2	47
Osteoprotegerin regulates vascular function through syndecan-1 and NADPH oxidase-derived reactive oxygen species	47
Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease	44
Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice	44
Correction: Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C	43
Antiviral activities of hemp cannabinoids	42
Renal hypertrophy and hyperfiltration is enhanced in early acquired compared with a congenital solitary function kidney model in sheep	42
Oxytocin: much more than childbirth and milk letdown	41
Endothelin receptor antagonism improves glucose handling, dyslipidemia, and adipose tissue inflammation in obese mice	41
Hypertension induces gonadal macrophage imbalance, inflammation, lymphangiogenesis, and dysfunction	40
Maternal high-fat diet regulates offspring hepatic ABCG5 expression and cholesterol metabolism via the gut microbiota and its derived butyrate	39

Tetramethylpyrazine attenuates renal tubular epithelial cell ferroptosis in contrast-induced nephropathy by inhibiting transferrin receptor and intracellular reactive oxygen species	39
Vascular contributions to cognitive impairment and dementia: the emerging role of 20-HETE	35
Correction: Silencing GOLGA8B inhibits cell invasion and metastasis by suppressing STAT3 signaling pathway in lung squamous cell carcinoma	34
Targeting TLR4/3 using chlorogenic acid ameliorates LPS+POLY I:C-induced acute respiratory distress syndrome via alleviating oxidative stress-mediated NLRP3/NF-κB axis	34
The membrane-associated protein 17 (MAP17) is up-regulated in response to empagliflozin on top of RAS blockade in experimental diabetic nephropathy	32
Sex, sepsis and the brain: defining the role of sexual dimorphism on neurocognitive outcomes after infection	32
Differential changes in end organ immune cells and inflammation in salt-sensitive hypertension: effects of increasing M2 macrophages	32
Annexin A1 treatment prevents the evolution to fibrosis of experimental nonalcoholic steatohepatitis	32