OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical Science is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
α-Adrenergic blockade prevented environmental temperature reduction-induced transient portal pressure surge in cirrhotic and portal hypertensive rats	325
Expression of Concern: Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression	240
Measuring muscle protein synthesis in humans and the influence of nutritional state	237
Effect of metformin in a novel experimental model of peripheral artery disease	202
The fatty acid imbalance of cystic fibrosis exists at birth independent of feeding in pig and ferret models	174
Novel preventive effect of isorhamnetin on electrical and structural remodeling in atrial fibrillation	145
Maintaining energy provision in the heart: the creatine kinase system in ischaemia–reperfusion injury and chronic heart failure	112
Paradoxical effects of osteoprotegerin on vascular function: inhibiting inflammation while promoting oxidative stress?	88
Diminished Rbfox1 increases vascular constriction by dynamically regulating alternative splicing of CaV1.2 calcium channel in hypertension	73
Severe psychiatric disorders and general medical comorbidities: inflammation-related mechanisms and therapeutic opportunities	62
Cardiovascular research at the Heart of Clinical Science	58
Metal regulation of Mycobacterium tuberculosis SufB intein splicing at the host–pathogen crossroad	58
Transcriptome-based exploration of potential molecular targets and mechanisms of selenomethionine in alleviating renal ischemia–reperfusion injury	49
Osteoprotegerin regulates vascular function through syndecan-1 and NADPH oxidase-derived reactive oxygen species	48
Antiviral activities of hemp cannabinoids	47
CEACAM5 inhibits the lymphatic metastasis of head and neck squamous cell carcinoma by regulating epithelial–mesenchymal transition via inhibiting MDM2	47
Targeting TLR4/3 using chlorogenic acid ameliorates LPS+POLY I:C-induced acute respiratory distress syndrome via alleviating oxidative stress-mediated NLRP3/NF-κB axis	47
Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease	46
Tetramethylpyrazine attenuates renal tubular epithelial cell ferroptosis in contrast-induced nephropathy by inhibiting transferrin receptor and intracellular reactive oxygen species	46
Higher circulating ACE2 and DPP3 but reduced ACE and angiotensinogen in hyperreninemic sepsis patients	46
Correction: Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C	41
Renal hypertrophy and hyperfiltration is enhanced in early acquired compared with a congenital solitary function kidney model in sheep	39
Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice	38
Maternal high-fat diet regulates offspring hepatic ABCG5 expression and cholesterol metabolism via the gut microbiota and its derived butyrate	37
Hypertension induces gonadal macrophage imbalance, inflammation, lymphangiogenesis, and dysfunction	34

Circulating cell-free micro-RNA as biomarkers: from myocardial infarction to hypertension	33
Correction: Silencing GOLGA8B inhibits cell invasion and metastasis by suppressing STAT3 signaling pathway in lung squamous cell carcinoma	33
Differential changes in end organ immune cells and inflammation in salt-sensitive hypertension: effects of lowering blood pressure	31
IFN-γ induces acute graft-versus-host disease by promoting HMGB1-mediated nuclear-to-cytoplasm translocation and autophagic degradation of p53	30
Sex, sepsis and the brain: defining the role of sexual dimorphism on neurocognitive outcomes after infection	29
Annexin A1 treatment prevents the evolution to fibrosis of experimental nonalcoholic steatohepatitis	29
Serum proteomics links the cardiorespiratory biomarkers CTRC, OSM, and MMP-10 to exacerbation severity and number in patients with COPD	29
Adverse effects of ovarian cryopreservation and auto-transplantation on ovarian grafts and quality of produced oocytes in a mouse model	29
Utility of preclinical models of altered maternal nutrition to support the developmental origins of health and disease hypothesis	29