Drug and Chemical Toxicology

Article	Citations
Pinealectomy and melatonin administration in rats: their effects on pulmonary edema induced by α-naphthylthiourea	67
Tinospora Cordifolia and Arabinogalactan in combination modulates benzo(a)pyrene-induced genotoxicity during lung carcinogenesis	20
Cytotoxic effect and induction of apoptosis in human cervical cancer cells by a wood extract from Prosopis laevigata	20
Comparative study of the genotoxic activity of Artemisia vulgaris L. and Artemisia alba Turra extracts in vitro	20
Novel chlorinated oxime K870 protects rats against paraoxon poisoning better than obidoxime	18
Livogrit prevents Amiodarone-induced toxicity in experimental model of human liver (HepG2) cells and Caenorhabditis elegans by regulating redox homeostasis	16
Antioxidant capacity, acute and sub-acute oral toxicity, and in vivo anti-inflammatory effects of Tetradenia riparia hydroalcoholic extrac	15
Computational and experimental study of terpolymers: spectroscopic, thermal, thermochemical, molecular property, and in silico toxicity analysis	15
Dichlorophene activates aryl hydrocarbon receptor (AhR) and indoleamine 2, 3-dioxygenase 1 (IDO1) to mediate splenotoxicity in rat	15
Assessment of cardiotoxicity induced by PFOS exposure and mechanism research via untarget metabolomics	14
Gastroprotective mechanism of Talinum triangulare on ethanol-induced gastric ulcer in Wistar rats via inflammatory, antioxidant, and H	14
Long-term exposure to bisphenol-A causes oxidative stress-related alterations at the genetic and cellular levels in the mature ovary of adult zebrafish	13
Toxicity optimization of green zinc oxide quantum dots in zebrafish using Box-Behnken design: a novel approach for safer nanoparticle synthesis	13
The ameliorative effect of rosmarinic acid and epigallocatechin gallate against doxorubicin-induced genotoxicity	12
Investigation of the role of K ATP channels in the cytotoxic effect of cypermethrin on rat-derived aortic smooth muscle cells	12
Investigating the impact of external application of formalin and potassium permanganate on hematological, immunological, and biochemical profiles in Labeo rohita fingerl	12
Protective role of resveratrol and apigenin against toxic effects of bisphenol a in rat salivary gland	11
Quercetin prevents methylmercury-induced mitochondrial dysfunction in the cerebral cortex of mice	11
Sweet basil ( Ocimum basilicum ) leaf and seed extracts alleviate neuronal dysfunction in aluminum chloride-induced neurotoxicity in Drosophila melanogast	11
Eight-year epidemiological study for drug poisoning in Qassim, Saudi Arabia, 2008–2015	11
Oxidative stress and inflammatory markers in streptozotocin-induced acute and subacute toxicity response	11
Determination of histopathological effects and myoglobin, periostin gene-protein expression levels in Danio rerio muscle tissue after acaricide yoksorrun-5EC (hexythiazox) application	10
Evaluation of genotoxic and mitotoxic effects of TAF-loaded chitosan nanoparticles in HepG2 cells	10
Neurotoxic effects of carbamazepine on the mosquitofish Gambusia affinis	10
Aprepitant mitigates paclitaxel-induced neuropathic pain in rats via suppressing inflammatory pathways in dorsal root ganglia	10

Acute, repeated inhalation toxicity, respiratory system irritation, and mutagenicity studies of 1,1,2,2-tetrafluoroethane (HFC-134) as the impurity in the pharmaceutical propellant 1,1,1,2-tetrafluoro	10
The protective effects of capsaicin on oxidative damage-induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats	10
Omeprazole induces profibrotic gene expression in rat kidney: implication of TGF-β/Smad signaling pathway	10
Unraveling the hepatoprotective and anti-pancreatic cancer potential of Caralluma europaea : a comprehensive in vivo, in vitro and in sili	10
In vitro assessment of the antioxidative, toxicological and antimicrobial properties of battery of parabens	10
Evaluating Water bitter leaf (Struchium sparganophora) and Scent Leaf (Ocimum gratissimum)extracts as sources of nutraceuticals against manganese-induced toxicity in fruit fly model	10
Hepatic histopathological and morphometric changes in male mice exposed to rosuvastatin from pre-puberty to adulthood: a possible adaptive hepatic response	10
Effects of electrospun fiber curcumin on bisphenol A exposed Caco-2 cells	10
Genotoxic effects of gadobutrol and gadoversetamide active substances used in magnetic resonance imaging in human peripheral lymphocytesin vitro	10
Neuroprotective effects of fermented blueberry and black rice against particulate matter 2.5 μm-induced inflammation in vitro and in vivo	10
Lipid-lowering, anti-inflammatory, and hepatoprotective effects of isorhamnetin on acetaminophen-induced hepatotoxicity in mice	10
Alpha-mangostin attenuates the apoptotic pathway of abamectin in the fetal rats’ brain by targeting pro-oxidant stimulus, catecholaminergic neurotransmitters, and transcriptional regulation of reelin	9
The protective effect of N-acetyl cysteine against selenium toxicity and gamma irradiation in rats	9
Effect of chlorpyrifos on some biochemical changes in Cyprinus carpio: the protective effect of ellagic acid	9
Topiramate’s effects on normal and fatty liver	9
Exposure to emamectin benzoate confers cytotoxic effects on human molt-4 T-cells and possible ameliorative role of vitamin E and dithiothreitol	9
Amelioration of metabolic disorders in H9C2 cardiomyocytes induced by PM 2.5 treated with vitamin C	9
Hepatoprotective effects of norgalanthamine on carbon tetrachloride induced-hepatotoxicity in mice	8
Anticonvulsant effectiveness of scopolamine against soman-induced seizures in African green monkeys	8
Is a non-cytotoxic and non-genotoxic novel bioinspired dipeptide structure synthesis possible for theragnostic applications?	8
Changes in hormones, Leukocyte Telomere Length (LTL), and p16INK4a expression in SM-exposed individuals in favor of the cellular senescence	8
The role of ginger’s extract and N-acetylcysteine against docetaxel-induced oxidative stress and genetic disorder	8
Non-permitted food colorants induced neurotoxicity in cerebellum of rat brain	8
Chlorogenic acid attenuates cisplatin-induced ovarian injury in rats	7
N ω -nitro-L-arginine, a nitric oxide synthase inhibitor, attenuates nickel-induced neurotoxicity	7
Investigation of genotoxic effects of rhododendron honey using three mammalian bioassays in vivo	7
Silver nanoparticles’ impact on the gene expression of the cytosolic adaptor MyD-88 and the interferon regulatory factor IRF in the gills and digestive gland of mytilus galloprovinciali	7
Resveratrol-mediated cardioprotection against myocardial ischemia-reperfusion injury was revoked by statin-induced mitochondrial alterations	7
The PERK/ATF4/CHOP signaling branch of the unfolded protein response mediates cisplatin-induced ototoxicity in hair cells	6
Protective effects of resveratrol and avocado oil against paracetamol-induced hepatotoxicity in rats	6
A toxicological review of alkaloids	6
Toxicological evaluation of ethanolic extract of leaves from Doliocarpus dentatus in Swiss mice	6
Formulation and evaluation of solid lipid nanoparticles loaded with papaya seed chloroform extract for long-term antifertility effects on the male rat, Bandicota bengalensis	6
Evaluating the therapeutic effect and toxicity of theophylline in infertile men with asthenoteratozoospermia: a double-blind, randomized clinical trial study	6
Population pharmacokinetics and pharmacodynamics of L-asparaginase and its impact on the development of pancreatitis and hypersensitivity reactions in children with leukemia under treatment	6
Apoptosis is involved in paraoxon-induced histological changes in rat cerebellum	6
The effects of minocycline in improving of methamphetamine withdrawal syndrome in male mice	6
Taurine and enzymatically modified isoquercitrin synergistically protect against the methotrexate-induced cardiotoxicity in rats: antioxidant and antiapoptotic effects	6
In vitro evaluation of the selective cytotoxicity and genotoxicity of three synthetic ortho -nitrobenzyl derivatives in human cancer cell lines, with	6
Comparative toxicological evaluation of carvacrol, acetylcarvacrol anda fipronil-based pesticide in human blood cells	6
In silico and in vivo protective effect of Morus nigra leaves on oxidative damage induced by iron overload	6
Furan impairs cell function by inducing oxidative stress, DNA damage and apoptosis in mouse Sertoli cells in vitro	6
Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc/Nrf2-redox systems	6
Implications of atrazine concentrations in drinking water from Ijebu-North, Southwest Nigeria on the hypothalamic-pituitary-adrenal axis	5
Effects of ellagic acid in the testes of streptozotocin induced diabetic rats	5
Genotoxic and genoprotective effects of phytoestrogens: a systematic review	5
Piribedil and thymol mitigate vancomycin-evoked nephrotoxicity in rats through modulation of Keap-1/Nrf2/HO-1 and NF-κB/Bax/caspase 3 signalings	5
PM2.5from diesel exhaust attenuated fisetin mediated cytoprotection in H9c2 cardiomyocytes subjected to ischemia reoxygenation by inducing mitotoxicity	5
The inhibitory effects of pimozide, an antipsychotic drug, on voltage-gated K+ channels in rabbit coronary arterial smooth muscle cells	5
Rosuvastatin exposure in female Wistar rats alters uterine contractility and do not show evident (anti)estrogenic effects	5

Bromelain protects against cisplatin-induced ocular toxicity through mitigating oxidative stress and inflammation	5
Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells	5
Cadmium and ketoprofen accumulation influences aquatic ecosystem demonstrated using in-vivo zebrafish model	5
Neuroprotective effects of gastrodin against bisphenol A induced-ADHD-like symptoms in rats	5
Perfluorooctane sulfonate (PFOS) triggers migration and invasion of esophageal squamous cell carcinoma cells via regulation of Zeb1	5
Evaluation of acute and subacute dermal toxicity of antibacterial bioactive glass-infused surgical cotton gauze in Wistar rats	5
Interactive effect of carbendazim and imidacloprid on buffalo bone marrow derived mesenchymal stem cells: oxidative stress, cytotoxicity and genotoxicity	5
Correction	5
Opioid poisoning cases aged 50+ in the 2015–2020 National Poisoning Data System: suspected suicides versus unintentional poisoning and other intentional misuse/abuse	5
Amelioration of modified chronic unpredictable stress usingCelastrus paniculatusseed oil alone and in combination with fluoxetine	5
Fluvastatin alleviates doxorubicin-induced cardiac and renal toxicity in rats via regulation of oxidative stress, inflammation, and apoptosis associated genes expressions	5
Phytochemical composition, cytotoxicity, antioxidant and antimicrobial responses of Lavandula dentata L. grown under different levels of heavy metals stress condition	4
Manganese mitigates against hepatorenal oxidative stress, inflammation and caspase-3 activation in rats exposed to hexachlorobenzene	4
Should combined MTX and CoQ10 use be reconsidered in terms of steatosis? A biochemical, flow cytometry, histopathological experimental study	4
Toxicity of pesticide cocktails in amphibian larvae: understanding the impact of agricultural activity on aquatic ecosystems in the Salado River basin, Argentina	4
Assessing chromium toxicity across aquatic and terrestrial environments: a cross-species review	4
Correction	4
Atrazine residue in waters of Ijebu-North local government, Nigeria: implications on human health, hematological, and biochemical parameters	4
Determination of micronuclei frequency in Danio rerio for assessing genotoxicity induced by propineb	4
Lagerstroemia speciosa (L.) Pers., ethanolic leaves extract attenuates dapsone-induced liver inflammation in rats	4
Cytogenetic damage by vanadium(IV) and vanadium(III) on the bone marrow of mice	4
Assessment of Toxicity and Wound Healing Activity of Selaginella Bryopteris Extract	4
Invisible enemies: evaluating human health threats of mosquito repellents through animal studies	4
Tauroursodeoxycholic acid suppresses biliary epithelial cell apoptosis and endoplasmic reticulum stress by miR-107/NCK1 axis in a FXR-dependent manner	4
Co-administration of thymol and sulfoxaflor impedes the expression of reproductive toxicity in male rats	4
Exploring the toxicity profile of coriander ( C. sativum L.) essential oil: implications for translational toxicological research	4
Two cases report of febuxostat-induced acute liver injury: acute heart failure as a probable risk factor?	4
Antibiotic sorption onto MPs in terrestrial environment: a critical review of the transport, bioaccumulation, ecotoxicological effects and prospects	4
Protective effect of neurotensin receptor-1 agonist PD 149163 against lipopolysaccharide-induced gut toxicity in mice	4
Cytotoxicity of methamphetamine exposure on Sertoli cells: a pilot study with implications for male infertility	4
Repeated dose toxicity studies of Trichostatin A in Swiss albino mice through oral and intravenous route of administration with special emphasis on genotoxicity	4
Unraveling the neuroprotective mechanisms of naltrexone against aluminum-induced neurotoxicity	4
Anti-ischemic drug trimetazidine blocks mercury nephrotoxicity by suppressing renal redox imbalance, inflammatory stress and caspase-dependent apoptosis in rats	4
Outcome prediction of methadone poisoning in the United States: implications of machine learning in the National Poison Data System (NPDS)	4
Effects of low-dose ionizing radiation on the molecular pathways linking neurogenesis and autism spectrum disorders in zebrafish embryos	4
Assessment of redox homeostasis via genotoxicity, cytotoxicity, apoptosis and NRF-2 in colorectal cancer cell lines after treatment with Ganoderma lucidum extract	3
Chloroform extract of Calliandra portoricensis inhibits tumourigenic effect of N-methyl-N-nitrosourea and benzo(a)pyrene in breast experimental cancer	3
The incidence rate of allergic reactions induced by oxaliplatin is higher in patients with rectal cancer compared with colon cancer	3
Effects of taxifolin on tramadol-induced oxidative and inflammatory liver injury in rats: an experimental study	3
Hepatoprotective effects of a chemically-characterized extract from artichoke (Cynara scolymus L.) against AFB1-induced toxicity in rats	3
Sub-chronic toxicity of an aqueous extract of Epimedium sagittatum (Sieb. Et Zucc.) Maxim. in rats	3
Content of potentially toxic elements (PTEs) in coffee and coffee-based products: a meta-analysis study, Systematic review, and health risk assessment	3
Toxicological evaluation of LivLonga ® , a polyherbal combination, in rodents	3
Investigation of oxidative, inflammatory and apoptotic effects of favipiravir use alone and combined with vitamin C on brain tissue of elderly rats	3
Isolation and comparative genotoxicity screening of trichokonins VI and VIII on CHO-K1 cells	3
Carvacrol modulates antioxidant enzymes, DNA integrity, and apoptotic markers in zearalenone-exposed fetal rat liver	3
Evaluation of acute and 28-day repeated dose toxicity of Tolypocladium sinense soft capsule in Sprague-Dawley rats	3
Assessment of morin hydrate as a renal protective agent in rats subjected to methotrexate-induced nephrotoxicity	3
Vitamin E improves oxidative stress, apoptosis, and steroidogenesis impairment in glyphosate-induced mice	3
MiADMSA abrogates sodium tungstate-induced oxidative stress in rats	3
Assessment of imidacloprid induced genotoxicity in Pethia conchonius (Rosy barb), a common freshwater fish of India	3
In vitro cytogenotoxic and mutagenic effects of Commiphora myrrha essential oil	3
Ginsenoside Re attenuates 8-OH-DPAT-induced serotonergic behaviors in mice via interactive modulation between PKCδ gene and Nrf2	3
Sulfoxaflor insecticide exhibits cytotoxic or genotoxic and apoptotic potential via oxidative stress-associated DNA damage in human blood lymphocytes cell cultures	3
Introduced paeoniflorin reduces the main toxicity induced by diosbulbin B, the major toxic compound of Dioscorea bulbifera L.: involved inhibiting inflammation and ferro	3
Study on the acute toxicity of sodium taurocholate via zebrafish mortality, behavioral response, and NMR-metabolomics analysis	3
In vitro cytogenetic analysis of two different anti-phosphates (sevelamer hydrochloride and calcium carbonate) agents used by patients with hyperphosphatemia	3
Synthesized gold nanoparticles mediated by Crassocephalum rubens extract down-regulate KIM-1/NGAL genes and inhibit oxidative stress in cadmium-induced kidney damage in rats	3
NO-mediated DNA damage induced by polystyrene nanoparticles triggers program cell death in mesenchymal stem cells	3
Comparative evaluation of natural and artificial sweeteners from DNA damage, oxidative stress, apoptosis, to development using Drosophila melanogaster	3
Mitochondrial toxicity of selected natural compounds: in vitro assessment and in silico molecular docking and dynamics simulation	3
Synergistic hepatoprotective effects of ω-3 and ω-6 fatty acids from Indian flax and sesame seed oils against CCl 4 -induced oxidative stress-mediated liver damage i	3
Preparation, characterization, and toxicity evaluation of microemulsion formulation containing prunetin for potential oral applications	3
Distribution, metabolism, excretion, and toxicity of implanted silver: a review	3
Evaluation of subchronic toxicity of the compound of diphenhydramine hydrochloride and caffeine after 28 days of repeated oral administration in Sprague-Dawley rats and beagle dogs	3
D-ribose-L-cysteine exhibits neuroprotective activity through inhibition of oxido-behavioral dysfunctions and modulated activities of neurotransmitters in the cerebellum of Juvenile mice exposed to et	3
Asparagus falcatus L. (Asparagaceae) leaf extracts attenuate doxorubicin-induced renal toxicity via antioxidant, anti-inflammatory, and anti-apoptotic pathways	3
Acute and 13 weeks subchronic toxicological evaluation of the flavonoid-rich extract of Sophora flavescens	3
Evaluation of XQ528 tartrate on embryo-fetus developmental toxicity in SD rats and genotoxicity	3
Mitigating aluminum chloride-induced toxicity in Drosophila melanogaster with peptide fractions from Euphorbia species	3
Toxicological analysis of synthetic dye orange red on expression of NFκB-mediated inflammatory markers in Wistar rats	3
Ascorbic acid regulates in vitro and in vivo toxicogenetic effects of hydroxyurea on eukaryotic cells	3
Pelargonidin ameliorates reserpine-induced neuronal mitochondrial dysfunction and apoptotic cascade: a comparative in vivo study	3
DNA damage in workers exposed to mineral oils	3
Protective efficacy of ramelteon on methotrexate-induced DNA damage	3
Linolenic acid stimulates eryptosis and hemolysis through oxidative stress and CK1α/MLKL: protective role of melatonin, urea, and polyethylene glycol	3
Protective effects of Biebersteinia multifida on sub-chronic toxicity of DZN in male Wistar rats: biochemical, hematological, and oxidative stress indices	2
Neutralization of iron oxide magnetic nanoparticle aquatoxicity on Oncorhynchus mykiss via supplementation with ulexite	2
Flavonoid-rich fraction of Lasianthera africana leaves alleviates hepatotoxicity induced by carbon tetrachloride in Wistar rats	2
Interactions of alumina and polystyrene nanoparticles with the innate immune system of Galleria mellonella	2

Linalool reverses benzene-induced cytotoxicity, oxidative stress and lysosomal/mitochondrial damages in human lymphocytes	2
Probiotics modulation of the endotoxemic effect on the gut and liver of the lipopolysaccharide challenged mice	2
The system of self-consistent models based on quasi-SMILES as a tool to predict the potential of nano-inhibitors of human lung carcinoma cell line A549 for different experimental conditions	2
The protective effects of vitamins A, C, and E on zinc oxide nanoparticles (ZnO NPs)-induced liver oxidative stress in male Wistar rats	2
Reproductive and developmental toxicity of α-terpineol in Wistar rats	2
Antioxidant and in vitro cytogenotoxic properties of Amburana cearensis (Allemão) A.C.Sm. leaf extract	2
Humic acid attenuates cisplatin-induced nephrotoxicity in rats	2
Beneficial effects of adipose-derived stromal vascular fraction on testicular injury caused by busulfan	2
Naringenin blocks hepatic cadmium accumulation and suppresses cadmium-induced hepatotoxicity via amelioration of oxidative inflammatory signaling and apoptosis in rats	2
Fumaric acid protects rats from ciprofloxacin-provoked depression through modulating TLR4, Nrf-2, and p190-rho GTP	2
Protective effect of dexpanthenol against methotrexate-induced liver oxidative toxicity in rats	2
Morphine attenuates neurotoxic effects of MPTP in zebrafish embryos by regulating oxidant/antioxidant balance and acetylcholinesterase activity	2
Ninety-day oral toxicological profiling of Kolaviron (an extract of Garcinia kola) in male and female rats	2
Nanomaterials in biology and medicine: a new perspective on its toxicity and applications	2
Naringenin mitigates cadmium-induced cell death, oxidative stress, mitochondrial dysfunction, and inflammation in KGN cells by regulating the expression of sirtuin-1	2
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats	2
Toxicological assessment of electronic cigarette vaping: an emerging threat to force health, readiness and resilience in the U.S. Army	2
Phytochemical analysis, antioxidant activity and modulatory effect of aqueous leaf extract of Pistacia lentiscus L on oxaliplatin-induced oxidative stress in isolated ra	2
Assessment of genotoxicity and acute oral toxicity of a standardized Ocimum tenuiflorum extract (Holixer TM )	2
Verbascoside inhibits paraquate-induced pulmonary toxicity via modulating oxidative stress, inflammation, apoptosis and DNA damage in A549 cell	2
Methanol fraction ofFicus mucoso(welw) prevents iron-induced oxidative damage and alters mitochondrial dysfunction inDrosophila melanogaster	2
The ameliorative effect of methanol extract of Ricinodendron heudelotii (Baill.) leaves on paracetamol-induced hepatotoxicity in Wistar rats	2
1 H NMR-metabolomics studies on acute toxicity effect of lead in adult zebrafish ( Danio rerio ) model	2
Enhanced antibacterial and genoprotective properties of nanoliposomal Satureja hortensis L. essential oil	2
Genotoxic, biochemical, cytotoxic and biomolecular alterations in the early-life stage of zebrafish exposed to diphenyl ether	2
Lethal toxicity induced by combined ingestion of dietary acetic acid and carbamazepine	2
Single and repeat-dose toxicity and local tolerance assessment of newly developed oil emulsion adjuvant formulations for veterinary purposes	2
Renal tubular response to titanium dioxide nanoparticles exposure	2
Comparison of the cytotoxicity and zebrafish embryo toxicity of insect repellent ingredients: p-Menthane-3,8-diol synthesized by green chemistry from Eucalyptus citriodora	2
Ameliorative effects of nutritional minerals on lead-induced hematological alterations in male Wistar albino rats	2
Acute and sub-acute toxicity study of ethanol extract from Nectandra leucantha Nees & Mart. (Lauraceae) barks	2
Evaluation of oxidative stress and its association with drug therapy in inpatients treated for cocaine dependence	2
Screening the immunotoxicity of different food preservative agents on the model organism Galleria mellonella L. (Lepidoptera: Pyralidae) larvae	2
The impact of filtered water-pipe smoke on healthy versus cancer cells and their neurodegenerative role on AMPA receptor	2
The effect of cut sizes and pH of tobacco leaf in smokeless tobacco products on the pharmacokinetics of nicotine	2
Hesperidin via maintenance of mitochondrial function and antioxidant activity protects lithium toxicity in rat heart isolated mitochondria	2
Three-dimensional (3D) cell culture studies: a review of the field of toxicology	2
Exploring health beneficial effects of poisonous mushroom Paxillus involutus Batsch Fr.	2
Toothpastes for children and their detergent contents affect molecular mechanisms of odontogenesis in zebrafish embryos	2
Isometamidium chloride alters redox status, down-regulates p53 and PARP1 genes while modulating at proteomic level in Droso	2
Modulatory effect of myricitrin against chromosome instability and cytostasis induced by bleomycin and oxaliplatin in CHO-K1 cells	2
l -Theanine ameliorates motor deficit, mitochondrial dysfunction, and neurodegeneration against chronic tramadol induced rats model of Parkinson’s disease	2
Mutagenic and genotoxic in silico QSAR prediction of dimer impurity of gliflozins; canagliflozin, dapaglifozin, and emphagliflozin and in vitro	2
Synthesis and evaluation of small organic molecule as reactivator of organophosphorus inhibited acetylcholinesterase	2
Effects of idebenone and coenzyme Q10 on NLRP3/caspase-1/IL-1β pathway regulation on ethanol-induced hepatotoxicity in rats	2
Saffron stigma extract and crocin play an important neuroprotective role in therapeutic measures against benzo[a]pyrene-induced behavioral alterations in zebrafish	2
Potential neuroprotective effects of 2-hydroxypropyl-β cyclodextrin against amyloid β (1-42)-induced neurotoxicity on the rat hippocampus	2
Screening and toxicity evaluation of natural compounds as adenosine 2a and 2b receptor ligands: insights from molecular docking, dynamics, and ADMET analysis	2
A dual-acting aldose reductase inhibitor impedes oxidative and carbonyl stress in tissues of fructose- and streptozotocin-induced rats: comparison with antioxidant stobadine	2
Pre-clinical acute oral toxicity and subacute neurotoxicity risk assessments on sprague dawley rats treated with single dose or repeated doses of flavonoid-enriched fraction extracted from	2
Study on the acute and subchronic oral toxicity of Calculus Bovis Sativus in rats	1
Effect of lycopene on TiO 2 nanoforms induced oxidative stress and neuroinflammation in SH-SY5Y cells: an in vitro study	1
Construction of an explanatory model for predicting hepatotoxicity: a case study of the potentially hepatotoxic components of Gardenia jasminoides	1
Protective effects of herbal compounds against cyclophosphamide-induced organ toxicity: a pathway-centered approach	1
Protective effects of curcumin against valproic acid induced brain kidney and liver damage in rats	1
Borassus flabellifer Linn haustorium methanol extract mitigates fluoride-induced apoptosis by enhancing Nrf2/Haeme oxygenase 1 –dependent glutathione metabolism in intestinal epithe	1
Some relevant mitigating agents of chronic aflatoxin exposure: a treatise	1
Nebivolol alleviates liver damage caused by methotrexate via AKT1/Hif1α/eNOS signaling	1
Insight into the mechanism and toxicology of nitrofurantoin: a metabolomics approach	1
Influence of zinc oxide nanoparticles (ZnO NPs) on the hemocyte count and hemocyte-mediated immune responses of the Greater Wax Moth Galleria mellonella (Lepidoptera: Pyralidae)	1
Exogenous glutathione protects against gentamicin-induced acute kidney injury by inhibiting NF-κB pathway, oxidative stress, and apoptosis and regulating PCNA	1
Effects of chlorpyrifos toxicity on brain, pseudobranchial neurosecretory system and swimming performance of a catfish, Heteropneustes fossilis	1
The administration of methyl and butyl parabens interferes with the enzymatic antioxidant system and induces genotoxicity in rat testis: possible relation to male infertility	1
Modulation of mitochondrial permeability transition pore opening by Myricetin and prediction of its-drug-like potential usingin silicoapproach	1
Role of aluminum exposure on Alzheimer’s disease and related glycogen synthase kinase pathway	1
Pentoxifylline inhibits phosgene-induced lung injury via improving hypoxia	1
There and back again: a dendrimer’s tale	1
Acute exposure to environmentally relevant concentrations of pharmaceutical pollutants induces neurobehavioral toxicity in zebrafish ( Danio rerio )	1
Combined effect of fulvestrant and low dose BPA: comparative implications on EMT, apoptosis, and TGF-β1 signaling in HepG2 cells	1
Single acute and repeated subacute toxicity evaluations of Annona atemoya leaf extract with in vitro anti-inflammatory potential	1
Neurotoxic responses of rainbow trout ( Oncorhynchus mykiss ) exposed to fipronil: multi-biomarker approach to illuminate the mechanism in brain	1
L-Carnitine alleviates hepatic and renal mitochondrial-dependent apoptotic progression induced by letrozole in female rats through modulation of Nrf-2, Cyt c and CASP-3 signaling	1
Damage to the sarcoplasmic reticulum by venom of the Mexican black-tailed rattlesnake ( Crotalus molossus nigrescens ): inhibition of the Ca 2+	1
Ameliorating effect of rutin against diclofenac-induced cardiac injury in rats with underlying function of FABP3, MYL3, and ANP	1
l-Thyroxine induces left ventricular remodeling and fibrosis in rats by upregulating miR-21 in a reactive oxygen-dependent mechanism: a protective role of N-acetylcysteine	1
Oleuropein mitigates acetaminophen overdose-induced kidney injury in male rats by enhancing antioxidant defense and suppressing inflammatory and apoptotic pathways	1
New oxomethacrylate and acetamide: synthesis, characterization, and their computational approaches: molecular docking, molecular dynamics, and ADME analyses	1
Effects of carvacrol on ketamine-induced cardiac injury in rats: an experimental study	1
Hydromorphone impurity 2,2-bishydromorphone does not exert mutagenic and clastogenic properties via in silico QSAR prediction and in vitro Ames and micronucleus test	1
Carbamazepine-induced renal toxicity may be associated with oxidative stress and apoptosis in male rat	1
Effect of adenosine triphosphate on methylphenidate-induced oxidative and inflammatory kidney damage in rats	1
Orally administered zingerone does not mitigate alcohol-induced hepatic oxidative stress in growing Sprague Dawley rat pups	1
Protective effect of chrysin, a flavonoid, on the genotoxic activity of carboplatin in mice	1
Ameliorative role of inducible nitric oxide synthase inhibitors against sodium arsenite-induced renal and hepatic dysfunction in rats	1
Identification and genotoxicity evaluation of potential impurities in rabeprazole sodium using in silico and in vitro analyses	1
Identification, trace level quantification, and in silico assessment of potential genotoxic impurity in Famotidine	1
Genotoxic and mutagenic potential of 7-methylxanthine: an investigational drug molecule for the treatment of myopia	1
Neuroprotective potential of solanesol against tramadol induced zebrafish model of Parkinson’s disease: insights from neurobehavioral, molecular, and neurochemical evidence	1
Intestinal epithelial damage due to herbal compounds – an in vitro study	1
In silico molecular docking and in vitro analysis of atomoxetine	1
Artemisia vulgaris L., Artemisia alba Turra and their constituents reduce mitomycin C-induced genomic instability in human peripheral blood lymphocyte	1
Comparative evaluation of the effects of bisphenol derivatives on oxidative stress parameters in HepG2 cells	1
Interconnected environmental challenges: heavy metal–drug interactions and their impacts on ecosystems	1
Olea europaea L. leaf extract mitigates pulmonary inflammation and tissue destruction in Wistar rats induced by concurrent exposure to noise and tolue	1
Long term integrated biomarker responses in freshwater African catfish Clarias gariepinus exposed to a new brand of herbicide fluazifop-p-butyl	1