Neurotoxicology

Article	Citations
The SH-SY5Y human neuroblastoma cell line, a relevant in vitro cell model for investigating neurotoxicology in human: Focus on organic pollutants	63
Neurotoxic potential of polystyrene nanoplastics in primary cells originating from mouse brain	58
Quercetin provides protection against the peripheral nerve damage caused by vincristine in rats by suppressing caspase 3, NF-κB, ATF-6 pathways and activating Nrf2, Akt pathways	57
Vincristine-induced peripheral neuropathy: A mini-review	49
Anti-epileptic activity of daidzin in PTZ-induced mice model by targeting oxidative stress and BDNF/VEGF signaling	45
Multifunctional roles of zinc in Alzheimer’s disease	44
Lycopene protects against central and peripheral neuropathy by inhibiting oxaliplatin-induced ATF-6 pathway, apoptosis, inflammation and oxidative stress in brains and sciatic tissues of rats	44
Epigenetic influence of environmentally neurotoxic metals	43
Neurotoxicity assessment of triazole fungicides on mitochondrial oxidative respiration and lipids in differentiated human SH-SY5Y neuroblastoma cells	42
Mitochondrial iron metabolism and neurodegenerative diseases	37
Prenatal PM2.5 exposure and behavioral development in children from Mexico City	36
Formononetin attenuates H2O2-induced cell death through decreasing ROS level by PI3K/Akt-Nrf2-activated antioxidant gene expression and suppressing MAPK-regulated apoptosis in neuronal SH-SY5Y cells	36
Neuropsychological Effects of Mercury Exposure in Children and Adolescents of the Amazon Region, Brazil	36
Baicalein protects against MPP+/MPTP-induced neurotoxicity by ameliorating oxidative stress in SH-SY5Y cells and mouse model of Parkinson’s disease	35
Concentrated ambient fine particulate matter (PM2.5) exposure induce brain damage in pre and postnatal exposed mice	35
Prenatal phthalate exposure, oxidative stress-related genetic vulnerability and early life neurodevelopment: A birth cohort study	33
Neuroprotective effect of chrysin on isoniazid-induced neurotoxicity via suppression of oxidative stress, inflammation and apoptosis in rats	33
Association between aluminum in drinking water and incident Alzheimer’s disease in the Canadian Study of Health and Aging cohort	32
Astrocyte-derived exosomes carry microRNA-17-5p to protect neonatal rats from hypoxic-ischemic brain damage via inhibiting BNIP-2 expression	31
Fenobucarb-induced developmental neurotoxicity and mechanisms in zebrafish	30
Air pollution, depressive and anxiety disorders, and brain effects: A systematic review	30
Anti-inflammatory and neuroprotective effects of natural cordycepin in rotenone-induced PD models through inhibiting Drp1-mediated mitochondrial fission	30
Pesticides applied to crops and amyotrophic lateral sclerosis risk in the U.S	29
Mercury: selenium interactions and health implications	28
Taurine improves neuron injuries and cognitive impairment in a mouse Parkinson’s disease model through inhibition of microglial activation	27

Association of arsenic exposure and cognitive impairment: A population-based cross-sectional study in China	26
Knockdown of long non-coding RNA AL049437 mitigates MPP+ -induced neuronal injury in SH-SY5Y cells via the microRNA-205-5p/MAPK1 axis	25
Paternal factors in neurodevelopmental toxicology: THC exposure of male rats causes long-lasting neurobehavioral effects in their offspring	25
IDO-1 inhibition protects against neuroinflammation, oxidative stress and mitochondrial dysfunction in 6-OHDA induced murine model of Parkinson’s disease	25
Impact of environmental toxicants on p38- and ERK-MAPK signaling pathways in the central nervous system	25
Metabolic profiling in human SH-SY5Y neuronal cells exposed to perfluorooctanoic acid (PFOA)	25
Targeting sirtuin activity with nicotinamide riboside reduces neuroinflammation in a GWI mouse model	24
Neuromodulatory effects of hesperidin against sodium fluoride-induced neurotoxicity in rats: Involvement of neuroinflammation, endoplasmic reticulum stress, apoptosis and autophagy	24
Analysis of behavioral changes in zebrafish (Danio rerio) larvae caused by aminoglycoside-induced damage to the lateral line and muscles	23
The ameliorative effect of nanoselenium on histopathological and biochemical alterations induced by melamine toxicity on the brain of adult male albino rats	22
Protective effect of alpha-linoleic acid on Aβ-induced oxidative stress, neuroinflammation, and memory impairment by alteration of α7 nAChR and NMDAR gene expression in the hippocampus of rats	22
Brainstem atrophy in Gulf War Illness	22
Neuropathology associated with exposure to different concentrations and species of mercury: A review of autopsy cases and the literature	22
Application of the hard and soft, acids and bases (HSAB) theory as a method to predict cumulative neurotoxicity	22
Mechanisms of oxidative stress in methylmercury-induced neurodevelopmental toxicity	22
Use of new psychoactive substances to mimic prescription drugs: The trend in France	21
Neuroprotective effects of catechin and quercetin in experimental Parkinsonism through modulation of dopamine metabolism and expression of IL-1β, TNF-α, NF-κB, IκKB, and p53 genes in male Wistar rats	21
Polychlorinated biphenyls induce oxidative stress and metabolic responses in astrocytes	21
Molecular mechanisms for the antidepressant-like effects of a low-dose ketamine treatment in a DFP-based rat model for Gulf War Illness	20
Exposure to bisphenol A differentially impacts neurodevelopment and behavior in Drosophila melanogaster from distinct genetic backgrounds	19
Critical windows of susceptibility in the association between manganese and neurocognition in Italian adolescents living near ferro-manganese industry	19
Investigation of the effects of berberine on bortezomib-induced sciatic nerve and spinal cord damage in rats through pathways involved in oxidative stress and neuro-inflammation	19
PEGylated superparamagnetic iron oxide nanoparticles (SPIONs) ameliorate learning and memory deficit in a rat model of Alzheimer’s disease: Potential participation of STIMs	19
Does paraquat cause Parkinson’s disease? A review of reviews	18
AlCl3 induced learning and memory deficit in zebrafish	18
Investigating the neurotoxicity of environmental pollutants using zebrafish as a model organism: A review and recommendations for future work	18
Neurotoxicity in Gulf War Illness and the potential role of glutamate	18
Effect of suvorexant on morphine tolerance and dependence in mice: Role of NMDA, AMPA, ERK and CREB proteins	18
The uses of 3D human brain organoids for neurotoxicity evaluations: A review	18
Oxidative stress and decreased dopamine levels induced by imidacloprid exposure cause behavioral changes in a neurodevelopmental disorder model in Drosophila melanogaster	18
RETRACTED: Melatonin rescues the mice brain against cisplatin-induced neurodegeneration, an insight into antioxidant and anti-inflammatory effects	18
Amyotrophic lateral sclerosis and lead: A systematic update	18
TREM2 ameliorates anesthesia and surgery-induced cognitive impairment by regulating mitophagy and NLRP3 inflammasome in aged C57/BL6 mice	17
Bisphenol-A inhibits mitochondrial biogenesis via impairment of GFER mediated mitochondrial protein import in the rat brain hippocampus	17
Pregnancy exposure to carbon black nanoparticles induced neurobehavioral deficits that are associated with altered m6A modification in offspring	16
Exposure to acrylamide decreases noradrenergic axons in rat brain	16
Neuroprotective effects of cannabidiol on dopaminergic neurodegeneration and α-synuclein accumulation in C. elegans models of Parkinson’s disease	16
Astragalin attenuates AlCl3/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation	16
Vitamin A deficiency exacerbates autism-like behaviors and abnormalities of the enteric nervous system in a valproic acid-induced rat model of autism	16
Depression and anxiety in a manganese-exposed community	16
Developmental neurotoxicity of MDMA. A systematic literature review summarized in a putative adverse outcome pathway	16
Edaravone attenuates cadmium-induced toxicity by inhibiting oxidative stress and inflammation in ICR mice	16
Ameliorative effects of flavonoids and polyketides on the rotenone induced Drosophila model of Parkinson’s disease	16
Arsenic induces autophagy-dependent apoptosis via Akt inactivation and AMPK activation signaling pathways leading to neuronal cell death	16
Dihydroactinidiolide regulates Nrf2/HO-1 expression and inhibits caspase-3/Bax pathway to protect SH-SY5Y human neuroblastoma cells from oxidative stress induced neuronal apoptosis	15
Effects of concentrated ambient ultrafine particulate matter on hallmarks of Alzheimer’s disease in the 3xTgAD mouse model	15
Role of melatonin in TLR4-mediated inflammatory pathway in the MTPT-induced mouse model	15
Methylmercury chloride exposure aggravates proinflammatory mediators and Notch-1 signaling in CD14+ and CD40+ cells and is associated with imbalance of neuroimmune function in BTBR T+ Itpr3tf/J mice	15
Effects of endocrine disrupting chemicals on myelin development and diseases	15
Naringin attenuates Bisphenol-A mediated neurotoxicity in hypertensive rats by abrogation of cerebral nucleotide depletion, oxidative damage and neuroinflammation	15

Genkwanin suppresses MPP+-induced cytotoxicity by inhibiting TLR4/MyD88/NLRP3 inflammasome pathway in a cellular model of Parkinson’s disease	15
Dihydropyrimidinone-derived selenoesters efficacy and safety in an in vivo model of Aβ aggregation	15
Biological determinants impact the neurovascular toxicity of nicotine and tobacco smoke: A pharmacokinetic and pharmacodynamics perspective	15
Mechanistic exploration of quercetin against metronidazole induced neurotoxicity in rats: Possible role of nitric oxide isoforms and inflammatory cytokines	15
Dietary glutamate and the brain: In the footprints of a Jekyll and Hyde molecule	14
Chronic exposure to low dose of bisphenol A causes follicular atresia by inhibiting kisspeptin neurons in anteroventral periventricular nucleus in female mice	14
Cholecystokinin-8 attenuates methamphetamine-induced inflammatory activation of microglial cells through CCK2 receptor	14
Comparison of neuropathology in rats following status epilepticus induced by diisopropylfluorophosphate and soman	14
Developmental Perfluorooctanesulfonic acid (PFOS) exposure as a potential risk factor for late-onset Alzheimer’s disease in CD-1 mice and SH-SY5Y cells	14
PI3K/AKT pathway mediates the antidepressant- and anxiolytic-like roles of hydrogen sulfide in streptozotocin-induced diabetic rats via promoting hippocampal neurogenesis	14
Thioredoxin-1 blocks methamphetamine-induced injury in brain through inhibiting endoplasmic reticulum and mitochondria-mediated apoptosis in mice	13
Fluoxetine-induced neurotoxicity at environmentally relevant concentrations in adult zebrafish Danio rerio	13
Chlorpyrifos, permethrin and cyfluthrin effect on cell survival, permeability, and tight junction in an in-vitro model of the human blood-brain barrier (BBB)	13
Remarkable migration propensity of dental pulp stem cells towards neurodegenerative milieu: An in vitro analysis	13
Early developmental exposure to bisphenol A and bisphenol S disrupts socio-cognitive function, isotocin equilibrium, and excitation-inhibition balance in developing zebrafish	13
Dietary fluoride intake during pregnancy and neurodevelopment in toddlers: A prospective study in the progress cohort	13
Alteration of protein profile in cerebral cortex of rats exposed to bisphenol a: a proteomics study	13
Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice	13
Neuromelanin formation exacerbates HAA-induced mitochondrial toxicity and mitophagy impairments	13
Neurotoxicity of sub-anesthetic doses of sevoflurane and dexmedetomidine co-administration in neonatal rats	13
Prenatal exposure to a mixture of organophosphate esters and intelligence among 8-year-old children of the HOME Study	13
The involvement of TRPV4 on the hypoxia-induced oxidative neurotoxicity and apoptosis in a neuronal cell line: Protective role of melatonin	12
Paternal cannabis extract exposure in rats: Preconception timing effects on neurodevelopmental behavior in offspring	12
Evaluation of the neurotoxic effects of engineered nanomaterials in C57BL/6J mice in 28-day oral exposure studies	12
Gestational and childhood urinary triclosan concentrations and academic achievement among 8-year-old children	12
Lead (Pb) exposure exacerbates behavioral and immune abnormalities by upregulating Th17 and NF-κB-related signaling in BTBR T+ Itpr3tf/J autistic mouse model	12
Visual contrast sensitivity in school-age Guadeloupean children exposed to chlordecone	12
Neuroprotective effects of the CTK 01512-2 toxin against neurotoxicity induced by 3-nitropropionic acid in rats	12
Resveratrol prevents haloperidol-induced mitochondria dysfunction through the induction of autophagy in SH-SY5Y cells	12
Protective effect of nanocurcumin against neurotoxicity induced by doxorubicin in rat’s brain	12
Sex differences in inflammatory cytokine levels following synthetic cathinone self-administration in rats	12
Neuroprotective effects of dopamine D2 receptor agonist on neuroinflammatory injury in olfactory bulb neurons in vitro and in vivo in a mouse model of allergic rhinitis	12
Dose-related biphasic effect of the Parkinson’s disease neurotoxin MPTP, on the spread, accumulation, and toxicity of α-synuclein	12
In silico identification of the potential molecular mechanisms involved in protective effects of prolactin on motor and memory deficits induced by 1,2-Diacetylbenzene in young and old rats	11
JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson’s disease: Mitochondrial protection and antioxidant properties	11
Xenobiotic transport and metabolism in the human brain	11
Selenium nanoparticles impart robust neuroprotection against deltamethrin-induced neurotoxicity in male rats by reversing behavioral alterations, oxidative damage, apoptosis, and neuronal loss	11
Prolonged fluoride exposure alters neurotransmission and oxidative stress in the zebrafish brain	11
Fluoride affects memory by altering the transcriptional activity in the central nervous system of Lymnaea stagnalis	11
Galangin mitigates DOX-induced cognitive impairment in rats: Implication of NOX-1/Nrf-2/HMGB1/TLR4 and TNF-α/MAPKs/RIPK/MLKL/BDNF	11
Estimating the causal effect of prenatal lead exposure on prepulse inhibition deficits in children and adolescents	11
Ursolic acid ameliorates amyloid β-induced pathological symptoms in Caenorhabditis elegans by activating the proteasome	11
Developmental exposure to methylmercury and resultant muscle mercury accumulation and adult motor deficits in mice	11
Cox regression model of prognostic factors for delayed neuropsychiatric sequelae in patients with acute carbon monoxide poisoning: A prospective observational study	11
Cognitive effects of the GSK-3 inhibitor “lithium” in LPS/chronic mild stress rat model of depression: Hippocampal and cortical neuroinflammation and tauopathy	11
Gasdermin D-mediated microglial pyroptosis exacerbates neurotoxicity of aflatoxins B1 and M1 in mouse primary microglia and neuronal cultures	11
Edaravone attenuates H2O2 or glutamate-induced toxicity in hippocampal neurons and improves AlCl3/D-galactose induced cognitive impairment in mice	11
Are ion channels potential therapeutic targets for Parkinson’s disease?	11
Mercury and neurochemical biomarkers in multiple brain regions of five Arctic marine mammals	10
Exposure to PM2.5 induces neurotoxicity, mitochondrial dysfunction, oxidative stress and inflammation in human SH-SY5Y neuronal cells	10
Exposure of particulate matter (PM10) induces neurodevelopmental toxicity in zebrafish embryos	10
Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate	10
Naringin enhances long-term potentiation and recovers learning and memory deficits of amyloid-beta induced Alzheimer’s disease-like behavioral rat model	10
Nuclear accumulation of histone deacetylase 4 (HDAC4) by PP1-mediated dephosphorylation exerts neurotoxicity in Pb-exposed neural cells	10
Curcumin attenuates spatial memory impairment by anti-oxidative, anti-apoptosis, and anti-inflammatory mechanism against methamphetamine neurotoxicity in male Wistar rats: Histological and biochemical	10
Bisphenol a affects neurodevelopmental gene expression, cognitive function, and neuromuscular synaptic morphology in Drosophila melanogaster	10
Ferroptosis contributes to methylmercury-induced cytotoxicity in rat primary astrocytes and Buffalo rat liver cells	10
Zinc nanoparticles ameliorate oxidative stress and apoptosis induced by silver nanoparticles in the brain of male rats	10
Mercury in dental amalgam: a risk analysis	10
Cerebral concentration and toxicity of endocrine disrupting chemicals: The implication of blood-brain interfaces	10
Fine particulate matter induces endoplasmic reticulum stress-mediated apoptosis in human SH-SY5Y cells	10
RETRACTED: Tranilast ameliorated subchronic silver nanoparticles-induced cerebral toxicity in rats: Effect on TLR4/NLRP3 and Nrf-2	10
Role of amyloid beta (25−35) neurotoxicity in the ferroptosis and necroptosis as modalities of regulated cell death in Alzheimer's disease	9
Lead exposure in the home environment: An overview of risks from cottage industries in Africa	9
Mitochondrial and transcriptome responses in rat dopaminergic neuronal cells following exposure to the insecticide fipronil	9
Peripherally administered persistent organic pollutants distribute to the brain of developing chicken embryo in concentrations relevant for human exposure	9
SB332235, a CXCR2 antagonist, ameliorates thioacetamide-induced hepatic encephalopathy through modulation of the PI3K/AKT pathways in rats	9
Endocytosis, trafficking and exocytosis of intact full-length botulinum neurotoxin type a in cultured rat neurons	9
Comparative assessment of blood Metal/metalloid levels, clinical heterogeneity, and disease severity in amyotrophic lateral sclerosis patients	9
Organophosphate insecticides disturb neuronal network development and function via non-AChE mediated mechanisms	9
Metal-induced neurotoxicity in a RAGE-expressing C. elegans model	9
Short-term neuronal effects of fumonisin B1 on neuronal activity in rodents	9
Tramadol-associated seizures in Egypt: Epidemiological, clinical, and radiological study	9
Suicidality among South Brazilian tobacco growers	9
Paraquat induces redox imbalance and disrupts glutamate and energy metabolism in the hippocampus of prepubertal rats	9
Biochanin A protects SH-SY5Y cells against isoflurane-induced neurotoxicity by suppressing oxidative stress and apoptosis	9
Pharmacological evaluation of bromelain in mouse model of Alzheimer’s disease	9
Effects of pramipexole on beta-amyloid1–42 memory deficits and evaluation of oxidative stress and mitochondrial function markers in the hippocampus of Wistar rat	9
JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats	9
Shedding light on the toxicity of SARS-CoV-2-derived peptide in non-target COVID-19 organisms: A study involving inbred and outbred mice	9

Behavioural, electrocorticographic, and electromyographic alterations induced by Nerium oleander ethanolic extract: Anticonvulsant therapeutics assessment

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