OOIR: Observatory of International Research

Papers

(The TQCC of Neurotoxicology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Chlorpyrifos and parathion regulate oxidative stress differentially through the expression of paraoxonase 2 in human neuroblastoma cell	138
Evaluation of mRNA markers in differentiating human SH-SY5Y cells for estimation of developmental neurotoxicity	113
Prenatal metal mixture concentrations and reward motivation in children	68
In silico identification of molecular mechanisms for stroke risk caused by heavy metals and their mixtures: Sponges and drugs involved	65
The uses of 3D human brain organoids for neurotoxicity evaluations: A review	53
Ketamine-induced neurotoxicity is mediated through endoplasmic reticulum stress in vitro in STHdhQ7/Q7 cells	46
Household based-pyrethroids on adult zebrafish (Danio rerio) exert behavioral and cholinergic changes in different brain regions	44
Abeta peptides disrupt the barrier integrity and glucose metabolism of human induced pluripotent stem cell-derived brain microvascular endothelial cells	37
JM-20 affects GABA neurotransmission in Caenorhabditis elegans	37
Editorial Board	36
Improvement of non-motor and motor behavioral alterations associated with Parkinson-like disease in Drosophila melanogaster: Comparative effects of treatments with hesperidin and L-dopa	36
Amphetamine-induced neurite injury in PC12 cells through inhibiting GAP-43 pathway	35
Spontaneous partial recovery of striatal dopaminergic uptake despite nigral cell loss in asymptomatic MPTP-lesioned female minipigs	35
4-EA-NBOMe, an amphetamine derivative, alters glutamatergic synaptic transmission through 5-HT1A receptors on cortical neurons from Sprague Dawley rat and pyramidal neurons from C57BL/6 mouse	35
Predicted versus observed activity of PCB mixtures toward the ryanodine receptor	33
The combined effects of HSV-1 glycoprotein D and aluminum hydroxide on human neuroblastoma cells: Insights into oxidative DNA damage, apoptosis, and epigenetic modifications	31
PRDX1 affects acrylamide-induced neural damage through the PTEN/AKT signaling pathway	31
ALDH2 inhibition by lead and ethanol elicits redox imbalance and mitochondrial dysfunction in SH-SY5Y human neuroblastoma cell line: Reversion by Alda-1	30
Analysis of serum levels of organochlorine pesticides and related factors in Parkinson’s disease	30
The effects of oral gestational particulate matter 10 exposure: Insights into neurodevelopmental milestones, inhibitory control, adult sociability, and object recognition	29
Jatamansinol from Nardostachys jatamansi (D.Don) DC. Protects Aβ42-Induced Neurotoxicity in Alzheimer's Disease Drosophila Model	29
Postnatal methylmercury exposure and neurodevelopmental outcomes at 7 years of age in the Seychelles Child Development Study Nutrition Cohort 2	29
The contributions of neonatal inhalation of copper to air pollution-induced neurodevelopmental outcomes in mice	28
Corrigendum to “Jatamansinol from Nardostachys jatamansi (D.Don) DC. Protects Aβ42-induced neurotoxicity in Alzheimer's disease Drosophila model”, [Neurotoxicology 90 (2022) 62–78]	28
In silico and In vivo protective effect of biochanin-A mitigating doxorubicin- induced cognitive deficits and neuroinflammation: Insights to the role of p-Tau and miR-132	28

Neuroprotective effects of dopamine D2 receptor agonist on neuroinflammatory injury in olfactory bulb neurons in vitro and in vivo in a mouse model of allergic rhinitis	28
Retraction notice to “Tranilast ameliorated subchronic silver nanoparticles-induced cerebral toxicity in rats: Effect on TLR4/NLRP3 and Nrf-2” [NeuroToxicology 82 (2021) 167–176]	28
Alcohol induced impairment/abnormalities in brain: Role of MicroRNAs	27
Editorial Board	27
Neuroprotective effect of quercetin and nano-quercetin against cyclophosphamide-induced oxidative stress in the rat brain: Role of Nrf2/ HO-1/Keap-1 signaling pathway	27
Fine particulate matter induces endoplasmic reticulum stress-mediated apoptosis in human SH-SY5Y cells	27
Nano polystyrene induced changes in anxiety and learning behaviour are mediated through oxidative stress and gene disturbance in mouse brain regions	27
Neuronal degeneration, mitochondrial dysfunction, and disturbance of movements induced by rotenone in the ascidian Styela plicata	26
Cannabis use in Parkinson’s disease: Patient access to medical cannabis and physician perspective on product safety	25
Tropospheric ozone effect on olfactory perception and olfactory bulb dopaminergic interneuron excitability	24
Mechanisms of developmental neurotoxicity of Dechlorane Plus, a recently identified persistent organic pollutant: An in silico study	23
Repeated toluene and cyclohexane inhalation produces differential effects on HPA and HPT axes in adolescent male rats	23
Ameliorating age-dependent effects of resveratrol on VPA-induced social impairments and anxiety-like behaviors in a rat model of neurodevelopmental disorder	23
Long-term exposure to ionic liquid [C8mim]Br induces the potential risk of anxiety and memory deterioration through disturbing neurotransmitter systems	23
Atractylon, a novel dopamine 2 receptor agonist, ameliorates Parkinsonian like motor dysfunctions in MPTP-induced mice	23
Infant neurodevelopment and behavior in Guadeloupe after lead exposure and Zika maternal infection during pregnancy	23
Ketamine modulates neural stem cell differentiation by regulating TRPC3 expression through the GSK3β/β-catenin pathway	22
TREM2 ameliorates anesthesia and surgery-induced cognitive impairment by regulating mitophagy and NLRP3 inflammasome in aged C57/BL6 mice	22
Hippocampal apoptosis: Molecular mechanisms triggered by toxic cannabinoid exposure: A narrative review	22
Prolonged ethanol exposure alters glutamate uptake leading to astrogliosis and neuroinflammation in adult zebrafish brain	21
Association of plasma metals with resting-state functional connectivity in ischemic stroke	21
Assessing neuropsychological disorders affecting pottery workers occupationally exposed to air pollutants	20
Do toenail manganese and iron levels reflect brain metal levels or brain metabolism in welders?	20
Are ion channels potential therapeutic targets for Parkinson’s disease?	20
Brief postnatal exposure to bisphenol A affects apoptosis and gene expression in the medial prefrontal cortex and social behavior in rats with sex specificity	20
Pathological methamphetamine exposure triggers the accumulation of neuropathic protein amyloid-β by inhibiting UCHL1	20
Impacts of neonatal methylmercury on behavioral flexibility and learning in spatial discrimination reversal and visual signal detection tasks	20
The effect of graphene oxide administration on the brains of male mice: Behavioral study and assessment of oxidative stress	20
Synergic control in asymptomatic welders during multi-finger force exertion and load releasing while standing	20
Age-dependent decline of copper clearance at the blood-cerebrospinal fluid barrier	20
Perinatal phthalate exposure increases developmental apoptosis in the rat medial prefrontal cortex	19
Identification of neurotoxicology (NT)/developmental neurotoxicology (DNT) adverse outcome pathways and key event linkages with in vitro DNT screening assays	18
Evaluation of sub-chronic toxicity of melamine via systematic or oral delivery in adult zebrafish based on behavioral endpoints	18
The role of carbon monoxide in aerotoxic syndrome	18
Predicting structural features of selected flavonoids responsible for neuroprotection in a Drosophila model of Parkinson’s disease	17
Adult-onset epilepsy and hippocampal pathology in a California sea lion (Zalophus californianus): A case study of suspected in utero exposure to domoic acid	17
The inhibitory influence of carvacrol on behavioral modifications, brain oxidation, and general inflammation triggered by paraquat exposure through inhalation	17
Unraveling the effects of prenatal anesthesia on neurodevelopment: A review of current evidence and future directions	17
Persisting neurobehavioral consequences of daily or intermittent paternal cannabis administration in F1 and F2 Rats	16
Evaluating how occupational exposure to organophosphates and pyrethroids impacts ADHD severity in Egyptian male adolescents	16
Characterization of pain-related behaviors, changes in bone microarchitecture and sensory innervation induced by chronic cadmium exposure in adult mice	16
Persistent proteomic changes in glutamatergic and GABAergic signaling in the amygdala of adolescent rats exposed to chlorpyrifos as juveniles	16
Combinations of classical and non-classical voltage dependent potassium channel openers suppress nociceptor discharge and reverse chronic pain signs in a rat model of Gulf War illness	16
The use of tocofersolan as a rescue agent in larval zebrafish exposed to benzo[a]pyrene in early development	16
Vitamin A ameliorates valproic acid-induced autism-like symptoms in developing zebrafish larvae by attenuating oxidative stress and apoptosis	16
Editorial Board	16
Changes in DNA methylation in APOE and ACKR3 genes in multiple sclerosis patients and the relationship with their heavy metal blood levels	16
Developmental lead exposure affects dopaminergic neuron morphology and modifies basal slowing response in Caenorhabditis elegans: Effects of ethanol	16
Implication of thyroid hormone receptors in methamphetamine neurocognitive effects	16
Assessment of the serum glucose/potassium GLU/K ratio as a predictor of intermediate syndrome following acute anticholinesterase exposure	16

Fluoxetine-induced neurotoxicity at environmentally relevant concentrations in adult zebrafish Danio rerio	16
Human blood markers of cholinergic neurotoxicity and neuropathy: A useful guide for laboratory applications	15
Environmental concentrations of glyphosate through direct or parental exposure alter nervous system development and reduce the fertility rate in zebrafish	15
Welding techniques and manganese concentrations in blood and brain: Results from the WELDFUMES study	15
Visuospatial processing and fine motor function among 7-years old Guadeloupe children pre- and postnatally exposed to the organochlorine pesticide chlordecone	15
Luteolin protects mouse hippocampal neuronal cells against isoflurane-induced neurotoxicity through miR-214/PTEN/Akt pathway	15
Identification of neural-relevant toxcast high-throughput assay intended gene targets: Applicability to neurotoxicity and neurotoxicant putative molecular initiating events	15
Impact of chronic exposure to legacy environmental contaminants on the corpus callosum microstructure: A diffusion MRI study of Inuit adolescents	15
Neuroprotective effect of Licochalcone A against aluminum chloride-induced neurotoxicity by reducing Aβ accumulation, oxidative stress and inflammatory reaction	15
Systemic administration of lipopolysaccharide induces hyperexcitability of prelimbic neurons via modulation of sodium and potassium currents	15
Edaravone attenuates cadmium-induced toxicity by inhibiting oxidative stress and inflammation in ICR mice	14
A review of monoamine oxidase (MAO) inhibitors in tobacco or tobacco smoke	14
Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro	14
Early life exposure to lead and its association with parent-reported aggression and conduct problems during childhood and adolescence	14
Lifetime air pollution exposure, cognitive deficits, and brain imaging outcomes: A systematic review	14
The impact of electronic cigarette aerosol exposure on spatial memory formation: Modulation by orally administered vitamin E	14
Cytotoxicity and transcriptome changes triggered by CuInS2/ZnS quantum dots in human glial cells	14
An efficient cellular image-based platform for high-content screening of neuroprotective agents against chemotherapy-induced neuropathy	13
An adverse outcome pathway for chemical-induced Parkinson’s disease: Calcium is key	13
Retraction notice to “Melatonin rescues the mice brain against cisplatin-induced neurodegeneration, an insight into antioxidant and anti-inflammatory effects” [Neurotoxicology 87 (2021) 1–10]	13
Retraction notice to “Neurotoxic effects of pregabalin dependence on the brain frontal cortex in adult male albino rats” [NeuroToxicology 83 (2021) 146–155]	13
Abnormal lipid metabolism and inflammatory response induced by aluminum led to the cognitive decline in mice	13
Synchrotron X-ray methods in the study of mercury neurotoxicology	13
Sex-specific associations between maternal phthalate exposure and neurodevelopmental outcomes in children at 2 years of age in the APrON cohort	13
Emerging roles of toll-like receptor 4 in chemotherapy-induced neurotoxicity	13
Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate	13
Protective mechanism of gold nanoparticles on human neural stem cells injured by β-amyloid protein through miR-21–5p/SOCS6 pathway	13
In silico identification of the potential molecular mechanisms involved in protective effects of prolactin on motor and memory deficits induced by 1,2-Diacetylbenzene in young and old rats	13
Gray matter morphometric biomarkers for distinguishing manganese-exposed welders from healthy adults revealed by source-based morphometry	12
Childhood exposure to pyrethroids and neurodevelopment in Canadian preschoolers	12
Social deficits in mice prenatally exposed to valproic acid are intergenerationally inherited and rescued by social enrichment	12
Fish consumption benefits health	12
Inside Front Cover - Aims & Scope, Copyright, Publication information, Orders & Claims, Advertising information, Author inquiries, Permissions, Funding body, Permanence of paper, Impressum (Ge	12
Neuroprotective potential of cinnamoyl derivatives against Parkinson’s disease indicators in Drosophila melanogaster and in silico models	12
Smoking, coffee intake, and Parkinson’s disease: Potential protective mechanisms and components	12
Liraglutide reduces oxidative stress and improves energy metabolism in methylglyoxal-induced SH-SY5Y cells	12
Methylmercury effects on avian brains	12
Manganese accumulation in red blood cells as a biomarker of manganese exposure and neurotoxicity	12
Assessing CaMPARI as new approach methodology for evaluating neurotoxicity	12
Editorial Board	12
Developmental neurotoxicity of bisphenol F and bisphenol S in animal model systems: A literature review	12
Developmental toxicity of bisphenol S in Caenorhabditis elegans and NODEF mice	12
Konzo risk factors, determinants and etiopathogenesis: What is new? A systematic review	12
Occupational exposure to pesticides as a potential risk factor for epilepsy	12
Diazepam and exercise training combination synergistically reduces lipopolysaccharide-induced anxiety-like behavior and oxidative stress in the prefrontal cortex of mice	11
Childhood exposure to organophosphate pesticides: Functional connectivity and working memory in adolescents	11
The stoichiometry of the α4β2 neuronal nicotinic acetylcholine receptors determines the pharmacological properties of the neonicotinoids, and recently introduced butenolide and sulfoximine	11
Time-dependent neuropathology in rats following organophosphate-induced status epilepticus	11
Comparison of predictive validity of two autism spectrum disorder rat models: Behavioural investigations	11
Editorial Board	11
The association of bone and blood manganese with motor function in Chinese workers	11
The association of prenatal manganese exposure with problem-solving skills and its mediation by the building blocks of executive function	10
Prenatal bisphenol A exposure in relation to behavioral outcomes in girls aged 4–5 and modification by socio-demographic factors in The Infant Development and Environment Study (TIDES)	10
Long-term LPS systemic administration leads to memory impairment and disturbance in astrocytic homeostasis	10
Proteomic profiling reveals neuronal ion channel dysregulation and cellular responses to DNA damage-induced cell cycle arrest and senescence in human neuroblastoma SH-SY5Y cells exposed to cypermethri	10
Neuromodulatory effects of hesperidin against sodium fluoride-induced neurotoxicity in rats: Involvement of neuroinflammation, endoplasmic reticulum stress, apoptosis and autophagy	10
α-synuclein-lack expression rescues methamphetamine-induced mossy fiber degeneration in dorsal hippocampal CA3	10
Effects of mixed metal exposures on MRI diffusion features in the medial temporal lobe	10
Pesticide exposure and cortical brain activation among farmworkers in Costa Rica	10
Blood glucose mediated the effects of cognitive function impairment related to aluminum exposure in Chinese aluminum smelting workers	10
Maternal exposure to polystyrene microplastics impairs social behavior in mouse offspring with a potential neurotoxicity	10
Mitochondrial iron metabolism and neurodegenerative diseases	10
Zinc (Zn) and adipose-derived mesenchymal stem cells (AD-MSCs) on MPTP-induced Parkinson’s disease model: A comparative evaluation of behavioral and immunohistochemical results	10
Leveraging artificial intelligence to advance the understanding of chemical neurotoxicity	10
Evaluating the toxic mechanism of 1,2-diacetylbenzene in neural cells/tissues: The favorable impact of silibinin	10
Prolonged sub-lethal exposure to galaxolide (HHCB) and tonalide (AHTN) promotes the metastatic potential of glioblastoma tumor spheroids	10
Chlorpyrifos, permethrin and cyfluthrin effect on cell survival, permeability, and tight junction in an in-vitro model of the human blood-brain barrier (BBB)	10