OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Natural Products is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models	102
Bioactive Cyclodepsipeptides from Cocultured Mangrove-Derived Aspergillus sp. and Penicillium sp.	73
Glenthmycins A–M: Macrocyclic Spirotetronate Polyketide Antibacterials from the Australian Pasture Plant-Derived Streptomyces sp. CMB-PB041	65
Discovery and Biosynthesis of Glycosylated Cycloheximide from a Millipede-Associated Actinomycete	47
Insights into the Biosynthesis of Kibdelomycin and Amycolamicin from Comparative Biosynthetic Gene Cluster Analysis and Precursor Incorporation Studies	40
Phenylhydrazone Alkaloids from the Deep-Sea Cold Seep Derived Fungus Talaromyces amestolkiae HDN21-0307	40
Issue Publication Information	38
Veraguamide E, a Marine Cyanobacterial Depsipeptide Targeting σ ₂ R/TMEM97: Chemical and Neurobiological Characterization	35
The Significance of Hypervariability and Conserved Motifs in Antimicrobial Peptides from Tree Frogs	35
Reconsideration of the Structures of Stemara-13(14)-en-18-ol and Related Diterpene Natural Products: Vinylic Hydrogen Chemical Shifts Are Key	35
Palladium-Catalyzed Direct Synthesis and Insecticidal Activity of Arylmatrine Derivatives	33
Proteomic Changes in Methicillin-Resistant Staphylococcus aureus Exposed to Cannabinoids	32
(±)-Polysiphenol and Other Analogues via Symmetrical Intermolecular Dimerizations: A Synthetic, Spectroscopic, Structural, and Computational Study	31
Drymariamides A–J, Antiadipogenic Cyclopeptides Incorporating Noncanonical Amino Acids from Drymaria cordata	31
Laeviganoids A–T, ent-Clerodane-Type Diterpenoids from Croton laevigatus	30
Biochemical and Structural Studies of the Carminomycin 4-O-Methyltransferase DnrK	29
Efficient Production of Flavonoid Glucuronides in Escherichia coli Using Flavonoid O-Glucuronosyltransferases Characterized from Marchantia polymorpha	28
Ouhanamide, an Antiparasitic Linear Lipopeptide from a Marine Okeania sp. Cyanobacterium	26
Discovery and Heterologous Expression of Functional 4- O -Dimethylallyl- l -tyrosine Synthases from Li	25
Chemistry of Herbarumin I, Stagonolide A, and Structurally Related Phytotoxic Ten-Membered Lactones: Oxidative Cleavage, Stereospecific Epoxidation, Transannulation, and Dimerization	25
Isolation and Biological Activity of 9-epiTetrodotoxin and Isolation of Tb-242B, Possible Biosynthetic Shunt Products of Tetrodotoxin from Pufferfish	25
Peniandranoids A–E: Meroterpenoids with Antiviral and Immunosuppressive Activity from a Penicillium sp.	25
Bacterial Espresso: Evaluating Accelerated Solvent Extraction for Selected Metabolite Recovery from Streptomyces Biomass	25
Platanosides, a Potential Botanical Drug Combination, Decrease Liver Injury Caused by Acetaminophen Overdose in Mice	24
Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC	24

Zelkovamycins F and G, Cyclopeptides with Cα-Methyl-threonine Residues, from an Endophytic Kitasatospora sp.	24
Triquinane Sesquiterpene Glycosides from the Basidiomycete Antrodiella zonata	23
Cytotoxic Irciniastatin Analogs and a New Thiazole Lipid from Sarcotragus spinosulus	23
Discovery of Chalcone Derivatives as Bifunctional Molecules with Anti-SARS-CoV-2 and Anti-inflammatory Activities	23
A Very Deep Graph Convolutional Network for¹³C NMR Chemical Shift Calculations with Density Functional Theory Level Performance for Structure Assignment	22
Structural Diversification of Pyrazinone Metabolites via Spontaneous Oxa-Michael Addition in Staphylococcus xylosus	22
Total Synthesis of Calanthoside, a Potential Hair Growth Stimulant: A Facile Synthetic Approach via One-Pot S- and O-Glucosidic Bond Formation	22
Synthesis and Evaluation of Natural and Unnatural Tetrahydrocannabiorcol for Its Potential Use in Neuropathologies	22
Ferroptosis Inhibitory Aromatic Abietane Diterpenoids from Ajuga decumbens and Structural Revision of Two 3,4-Epoxy Group-Containing Abietanes	21
Pyrrospirones K–Q, Decahydrofluorene-Class Alkaloids from the Marine-Derived Fungus Penicillium sp. SCSIO 41512	21
Chiral Optical Sensing of Amino Acids with 2-Trifluoromethyl Benzaldehyde for Ophiopogon japonicus Authentication	21
Emerging Investigators at the Forefront of Natural Products Research	21
Anti-Inflammatory Lindolin Alkaloids Repress the Transcription of the Microsomal Prostaglandin E ₂ Synthase-1 Gene in Macrophages	21
Issue Editorial Masthead	21
Suncheonosides E–M and Benzothioate Derivatives from the Marine-Derived Streptomyces sp. ZSN77	21
Elucidation of the Biosynthesis of Griseoluteic Acid in Streptomyces griseoluteus P510	21
Glyclauxins A–E: Dimeric Oxaphenalenone Aminoglycosides from an Australian Wasp Nest-Derived Fungus Talaromyces sp. CMB-MW102	20
Immunomodulatory Effects of New Phenanthrene Derivatives from Dendrobium crumenatum	20
DP4+App: Finding the Best Balance between Computational Cost and Predictive Capacity in the Structure Elucidation Process by DP4+. Factors Analysis and Automation	20
Discovery of an Indole-Quinazoline Alkaloid as an Anti-kidney Fibrotic Agent from the Marine-Derived Aspergillus clavatonanicus SCSIO 41444	20
Desferrioxamine Sharing among Microalgae-Associated Bacteria Enhances Iron-Limited Inhibition of Vibrio anguillarum	20
Activity of the Caged Xanthone Morellic Acid against Vancomycin-Resistant Enterococcus Infection by Targeting the Bacterial Membrane	19
Structural Characterization and Multiomics Analysis Reveal Extensive Diversity and Global Distribution of Kurstakin Lipopeptides	19
Cryptic Epoxytiglianes from the Kernels of the Blushwood Tree (Fontainea picrosperma)	19
Semisynthetic Studies Establish a Role for Conjugate Halide Exchange in the Formation of Chlorinated Pyrroloiminoquinones and Related Alkaloids	19
Altersteroids A–D, 9,11-Secosteroid-Derived γ-Lactones from an Alternaria sp.	19
Highly Concentrated Linear Guanidine Amides from the Marine Sipunculid Phascolosoma granulatum	19
Coriaceumins A–D, the First Nitrogen-Containing Crenulide Diterpenoids from the Brown Alga Dictyota coriacea Collected in the East China Sea	19
Isolation of Hydrazide-alkenes with Different Amino Acid Origins from an Azoxy-alkene-Producing Mutant of Streptomyces rochei 7434AN4	18
Ergone Derivatives from the Deep-Sea-Derived Fungus Aspergillus terreus YPGA10 and 25,28-Dihydroxyergone-Induced Apoptosis in Human Colon Cancer SW620 Cells	18
Coculture of Coastal Macroalga-Epiphytic Trichoderma Fungi for Microalgal Algicide Production Highlighted by an Iodinated Terpenoid	18
Pyranonaphthoquinones and Naphthoquinones from the Stem Bark of Ventilago harmandiana and Their Anti-HIV-1 Activity	18
Divergent Synthesis of Six Recent Berkeleylactones	18
Development of a Proton Spin Network Fingerprint Library to Support Mass Spectrometry-Based Identification of Pharmacophore-Bearing Constituents in the Botanical Supplement Centella asiatica	18
Bioactive Peptides from Caudate Amphibians: Synthesis and Assessment of Antioxidant and Antimicrobial Activities	18
Biochemical and Structural Insights of the N-Methyltransferase CyaF in Cyanogramide Biosynthesis	18
Salamandamide Lipodipeptides Are Biosynthetic Intermediate Shunt Products of the Nonamodular Nonribosomal Peptide Assembly Lines of the Viscosin Family	18
Sticklac-Derived Natural Compounds Inhibiting RNase H Activity of HIV-1 Reverse Transcriptase	18
Interaction Metabolomics to Discover Synergists in Natural Product Mixtures	18
Issue Publication Information	18
Total Synthesis and Anti-Inflammatory Activity of Tectoridin and Related Isoflavone Glucosides	18
Di- and Triterpenoids from the Rhizomes of Isodon amethystoides and Their Anti-inflammatory Activities	17
Selective Oxidation of Tertiary C–H Bonds in Steroids Catalyzed by the Heterodimeric Fe(II)/α-Ketoglutarate-Dependent Oxygenase TlxI–J	17
Cordycepsterols A–C, Anti-Inflammatory C₃₀ Ergosterols with a 6/6/6/5/6-Fused Ring System from Cordyceps militaris	17
Issue Editorial Masthead	17
Scaffold Hopping of Pristimerin Provides Derivatives Containing a Privileged Quinoxaline Substructure as Potent Autophagy Inducers in Breast Cancer Cells	17
Efficient and Selective Biosynthesis of a Precursor-Directed FK506 Analogue: Paving the Way for Click Chemistry	17
Hygromycin B Is a Highly Versatile Inducer of Secondary Metabolite Production Applicable Across Diverse Fungal Taxa	17
Antioxidant and Neuroprotective Effects of the First Tryptophyllin Found in Snake Venom (Bothrops moojeni)	17
Immunosuppressive Breviane Spiroditerpenoids from Penicillium bialowiezense Isolated from a Medicinal Plant	17

Sumatranins A–J: Lignans with Immunosuppressive Activity from Cleistanthus sumatranus	17
Modulation of in Vitro SARS-CoV-2 Infection by Stephania tetrandra and Its Alkaloid Constituents	17
Issue Publication Information	17
Isolation and Characterization of Anti-Mycobacterial Natural Products from a Petrosia sp. Marine Sponge	17
Dietary Terpenoid Lactones are Promiscuous Agonists of Bitter Taste Receptors (TAS2Rs)	16
ent-Clavilactone J and Its Quinone Derivative, Meroterpenoids from the Fungus Resupinatus sp.	16
The Discovery of Nocacyclomycins A–H, Cyclic Lipodepsipeptides from Nocardia sungurluensis YINM00009	16
Facile Synthesis and First Antifungal Exploration of Tetracyclic Meroterpenoids: (+)-Aureol, (−)-Pelorol, and Its Analogs	16
Norterpene Cyclic Peroxides from the Marine Sponge Diacarnus spinipoculum, Inhibitors of Transient Receptor Potential Ankyrin 1	16
Semi-Synthesis of Dimeric Cannabidiol Derivatives and Evaluation of their Affinity at Neurological Targets	16
Correction to Triterpenoid Saponins from Dianthus versicolor	16
CURE-ating the Substrate Scope and Functional Residues of Nonheme Iron(II) α-Ketoglutarate-Dependent Hydroxylase BesE	16
Cratenin, a Rare Oxylipin Marking Kleptopredation in Aeolid Nudibranchs	16
Highly N-Methylated Peptides from the Antarctic Sponge Inflatella coelosphaeroides Are Active against Plasmodium falciparum	16
Structure-Guided Discovery of Diverse Cytotoxic Dimeric Xanthones/Chromanones from Penicillium chrysogenum C-7-2-1 and Their Interconversion Properties	16
Shielding Effects of Aromatic (Indole) Ring for Structural Analysis	16
α-Synuclein Aggregation Inhibitory Procerolides and Diphenylalkanes from the Ascidian Polycarpa procera	16
Withanolides from Physalis angulata var. villosa and the Relative Configurational Revision of Some Known Analogs	16
Dichapetalins from the Twigs of Dichapetalum longipetalum with Cytotoxic Activities	16
Alkaloids and Polyacetylenes from Hippobroma longiflora with Antiangiogenesis Properties	16
Discovery of Biofilm Inhibitors from the Microbiota of Marine Egg Masses	16
Sonnerachromones A–G, Antiaging Chromones from the Fruit of Mangrove Sonneratia apetala	15
Purpurascenines A–C, Azepino-Indole Alkaloids from Cortinarius purpurascens: Isolation, Biosynthesis, and Activity Studies on the 5-HT_2A Receptor	15
Genome Mining of Linaridins Provides Insights into the Widely Distributed LinC Oxidoreductases	15
Dietary Supplement Adulteration: Laboratory Approaches to Risk Mitigation	15
Neurite Outgrowth-Inducing Drimane-Type Sesquiterpenoids Isolated from Cultures of the Polypore Abundisporus violaceus MUCL 56355	15
Design and Synthesis of Cytotoxic Water-Soluble Rocaglaol Derivatives against HEL Cells by Inhibiting Fli-1	15
Total Syntheses of the Amaryllidaceae Alkaloids Carltonines A–C and the Neuroprotective and Immunomodulatory Evaluation of Carltonine B	15
Microwave Radiation as an Inducer of Secondary Metabolite Production in Drosera rotundifolia In Vitro Plantlets	15
Isolation of the Anti-Inflammatory Agent Myceliostatin from a Methionine-Enriched Culture of Myceliophthora thermophila ATCC 42464	15
Issue Publication Information	15
Retraction of “Jejupeptins A and B: Polyketide–Cyclic Peptide Hybrids with Anti-Corticosterone Activity from Streptomyces sp. KCB15JA151”	15
Xyloketal B Reverses Nutritional Hepatic Steatosis, Steatohepatitis, and Liver Fibrosis through Activation of the PPARα/PGC1α Signaling Pathway	15
Correction to “Isolation and Synthesis of Azuriaplysins A and B, Bromoditerpenes with an α-Methylene Carbonyl from the Sea Hare Aplysia kurodai”	15
Structure Revision of Trichomide D by Total Synthesis	15
Subplenones A–J: Dimeric Xanthones with Antibacterial Activity from the Endophytic Fungus Subplenodomus sp. CPCC 401465	14
Turonicin A, an Antifungal Linear Polyene Polyketide from an Australian Streptomyces sp.	14
Euphohelides A–C, ent-Abietane-Type Norditerpene Lactones from Euphorbia helioscopia and Their Anti-Inflammatory Activities	14
Semisynthetic Derivatives of Perovskone: Development of a Promising Class of Antiprotozoal Lead Compounds	14
Discovery of neo-Clerodane Diterpenoids from Ajuga campylantha as Neuroprotective Agents against Ferroptosis and Neuroinflammation	14
Molecular Networking Reveals Indolo-Sesquiterpene Hybrids from the Marine-Derived Fungus Aspergillus terreus N4-9	14
Spirocitromycetin, a Fungal Polyketide with an Antiosteoporotic Pharmacophore	14
Pseudo-Enantiomeric Paraphaeolactones and Their Biosynthetic Derivatives from Paraphaeosphaeria sp. KT4192: A Proposition of a Favorskii Rearrangement for Their Biosynthesis	14
Discovery and Characterization of a cis -Casbene Diterpene Synthase from Streptomyces paromomycinus	14
Issue Publication Information	14
Karstmycins A–H: Trichostatin Analogues with PTP1B Inhibitory Activities from Streptomyces sp. DX6D14	14
Effects of the Anthocyanin Hirsutidin on Gastric Ulcers: Improved Healing through Antioxidant Mechanisms	14
Marine Bacterium Kordia algicida Reshapes Plankton Microbiome and Induces Metabolomic Rewiring, Independent of Heatwave or Worst-Case Climate Scenarios	14
Structural Revision of an Indole Alkaloid Trichindole B through Synthesis of Three Isomeric Compounds	14
Structure–Activity Relationships of Natural C-9-Methyl-Substituted 10-Membered Lactones and Their Semisynthetic Derivatives	14
Structural Characterization and Rat Aortic Vascular Reactivity of Bradykinin-Potentiating Peptides (BPPs) from the Snake Venom of Bothrops moojeni from Delta do Parnaíba Region, Brazil	14
Sadoamides A and B: Bacterial Tripeptides Incorporating Nonproteinogenic Amino Acids as Proteasome Inhibitors	14
Issue Editorial Masthead	14
LC-MS Guided Discovery and Biosynthetic Pathway of Coprisamides E–H, Cinnamic Acid-Containing Metabolites from the Marine Algae-Derived Streptomyces thermolineatus NAK03196	14
Isolation and Structure Determination of Akunolides, Macrolide Glycosides from a Marine Okeania sp. Cyanobacterium	14
Semisynthesis of Linariophyllenes A–C and Rumphellolide H, Structure Revisions and Proposed Biosynthesis Pathways	14
Isolation of 6,7-iso-Felinone A: A Configurational Reinvestigation of Related Fungal Metabolites	14
Structure Revision of Isomallotusinin to Mallotusinin by NMR-Based Conformational Analysis	14
Teleocidin B-4, a PKC Activator, Upregulates Hypoxia-Inducible Factor 1 (HIF-1) Activity by Promoting the Accumulation of HIF-1α Protein via the PKCα/mTORC Signaling Pathway	13
Value Addition to African Natural Product-Based Drug Discovery Initiatives	13
Lyngbyabellin Q, an Antimalarial Cyclic Peptide, and Its Acyclic Analog from a Cyanobacterial Biomat Dominated by Moorena sp.	13
Heterologous Production and Biosynthesis of Threonine-16:0dioic acids with a Hydroxamate Moiety	13
Bioactive Sesterterpenoids from the Mangrove-Derived Aspergillus sp. GXIMD 03023	13
Structure Determination of 1,3-Dioxolane-Containing Lipids from the Marine Sponge Leucetta sp. Using Chiral ¹H NMR Analysis of Model Systems	13
Curvisetone─A Male-Specific Tricyclic nor-Diterpenoid from the Springtail Sinella curviseta	13
Isolation of Core-Oxidized Lupine Alkaloids from the Leaves of Virgilia Oroboides and Semisynthesis of ent-	13
Mixtures Biotransformation: Multilayer Molecular Networking of Kratom Liver Metabolites	13
Developing the Natural Prenylflavone Artocarpin from Artocarpus hirsutus as a Potential Lead Targeting Pathogenic, Multidrug-Resistant Staphylococcus aureus, Persisters and Biofilms with	13
Issue Publication Information	13
19-Residue and 18-Residue Peptaibiotics Isolated from the Soil-Derived Fungus Trichoderma sp. XJ1083	13
Issue Publication Information	13
Lindenane-Based Sesquiterpenoid Hetero-Oligomers with Diverse Skeletons and Extracellular Regulated Protein Kinases Inhibitory Activity from Sarcandra glabra	13
The Terpenoid Alkaloids of Colobognath Millipedes: Insights into Structural Diversity and Function	13
Genomic and Metabolomic Analyses of Nocardiopsis maritima YSL2 as the Mycorrhizosphere Bacterium of Suaeda maritima (L.) Dumort	13
Triterpene Glycosides Tricycloiridals A–D with Cytotoxicity Isolated from Fungus Chrysosporium sp. YX1242	13
Psammaplin A and Its Analogs Attenuate Oxidative Stress in Neuronal Cells through Peroxisome Proliferator-Activated Receptor γ Activation	13
Stereocontrolled Synthesis of α-Branched Tetrahydropyrans by a One-Pot-Two-Step Photobiocatalytic Cascade of Citronellol	13
The Cytotoxic Cardiac Glycoside (−)-Cryptanoside A from the Stems ofCryptolepis dubiaand Its Molecular Targets	13
Issue Editorial Masthead	13
Issue Publication Information	13

Neuroprotective Indole Alkaloids from the Soil-Derived Fungus Trichocladium sp. XZ8	13
Rethinking Natural Product Discovery: A Complex Epistemological Approach Linking Chemical Ecology and Pharmacognosy	13
Alanine Mutagenesis Identifies Specific Amino Acids of Nemertide Alpha-1 Activity and Its Binding to Target Receptors	13
Precursor-Directed Biosynthesis of Neoantimycin Derivatives with Selective Cytotoxicity	13
The 6Ps of Preparing a Manuscript: Prior Preparation Prevents Potentially Poor Performance	13
Medullins A-H, Sesquiterpenes from Perenniporia medulla-panis, and Their Cellular Signaling Mechanism in HDF Cells	13
Special Issue in Honor of Professor Mary Garson AM	13
Gonystylones A–E, Antiproliferative 5,6-Dihydro-α-pyrones from the Plant Gonystylus borneensis	13
Correction to “Natural Products Have Increased Rates of Clinical Trial Success throughout the Drug Development Process”	13
Diaporaustalides A–L, Austalide Meroterpenoids from a Plant Endophytic Diaporthe sp.	12
PECAN Predicts Patterns of Cancer Cell Cytostatic Activity of Natural Products Using Deep Learning	12
Metabolomics-Guided Discovery of Bipolarolides H–O, New Ophiobolin-Type Sesterterpenes with Antibacterial Activity from the Marine-Derived Fungus Uzbekistanica storfjordensis sp. nov.	12
NMR-Metabolomic Profiling and Genome Mining Drive the Discovery of Cyclic Decapeptides from a Marine Streptomyces	12
Absolute Configuration of 12S-Deoxynortryptoquivaline from Ascidian-Derived Fungus Aspergillus clavatus Determined by Anisotropic NMR and Chiroptical Spectroscopy	12
Issue Publication Information	12
Protoilludane-Type and Related Nor-Sesquiterpenes from Phellinus hartigii and Their Anti-Hypertrophic Activities in Rat Cardiomyocytes	12
Discovery and Biosynthesis of Cinnamoyl-Containing Pepticinnamins Q–V Produced by the Marine-Derived Streptomyces sp. SCSIO 68065	12
Confirmation of the Disulfide Connectivity and Strategies for Chemical Synthesis of the Four-Disulfide-Bond-Stabilized Aspergillus giganteus Antifungal Protein, AFP	12
An Unexpected Activity of a Minor Cannabinoid: Cannabicyclol (CBL) Is a Potent Positive Allosteric Modulator of Serotonin 5-HT _1A Receptor	12
Expected and Unexpected Products from the Biochemical Oxidation of Bacterial Alkylquinolones with CYP4F11	12
Isolation and Structure Elucidation of Uric Acid Lowering Lipopeptides from an Okeania sp. Marine Cyanobacterium	12
Issue Editorial Masthead	12
Chirality Determination and Anti-inflammatory Activity of Phthalide Monomers in Angelica sinensis	12
Total Synthesis and SARS-CoV-2 3CLpro Inhibition Activities of (±)-Tuaimenal A and Its Derivatives	12
Goondansamycins A–H: Benzenoid Ansamycins from an Australian Volcanic Crater Soil-Derived Actinomadura sp. S4S-00069B08	12
Production of Kinanthraquinone D with Antimalarial Activity by Heterologous Gene Expression and Biotransformation in Streptomyces lividans TK23	12
Anti-Ferroptotic Effect of Cannabidiol in Human Skin Keratinocytes Characterized by Data-Independent Acquisition-Based Proteomics	12
Comparative Genomics and Metabolomics of Domesticated, Pladienolide-Producing Streptomyces Bacteria	12
Bioinspired Syntheses of Kuanoniamine D and Shermilamine B	12
Natural Rubrolides and Their Synthetic Congeners as Inhibitors of the Photosynthetic Electron Transport Chain	12
Anti-trypanosomal Lignans Isolated from Salvadoran Peperomia pseudopereskiifolia	12
Correction to “Highly Oxidized Germacranolides from Elephantopus tomentosus and the Configurational Revision of Some Previously Reported Analogues”	12
Diversity in Structure and Function: How Cyanobacterial Metallophores Reveal a Broadening Perspective of Microbial Metal-Chelators	12
Natural and Semisynthetic Immunomodulatory Luakuliide Labdane Diterpenoids	12
Tyrosinase Inhibitory Properties of Compounds Isolated from Artocarpus integer Roots	12
The Ethics of Publishing Biomedical and Natural Products Research	12
Amide Alkaloids as Privileged Sources of Senomodulators for Therapeutic Purposes in Age-Related Diseases	12
Miniaturized Cultivation Profiling Returns Indolo-Sesquiterpene Michael Adducts from the Australian Soil-Derived Aspergillus terreus CMB-SWF012	12
Tuaimenal A, a Meroterpene from the Irish Deep-Sea Soft Coral Duva florida , Displays Inhibition of the SARS-CoV-2 3CLpro Enzyme	12
Angucystemycins, Highly Oxygenated Acetylcysteine–Angucycline Hybrid Conjugates Derived from a Soil Metagenomic Library	12
Issue Editorial Masthead	12
Beyond Monomers: Discovery of Bioactive Naphthoquinone Heterodimers and Perenniporides from Pyrenochaetopsis Species	12
Issue Publication Information	12
Discovery of Spiroketal Acids and Antarmycin Analogues from Deep-Sea Derived Pseudonocardia antarctica and Its ΔantB3 Mutant Strain	12
Cyclopenta[bc]benzopyran Derivatives and Limonoids from Aglaia edulis with Cytotoxic and Anti-DENV Activity	12
Bathiapeptides: Polythiazole-Containing Peptides from a Marine Biofilm-Derived Bacillus sp.	12
Discovery of Coixol Derivatives as Potent Anti-inflammatory Agents	12
Discovery, Biological Activity, and Biosynthesis of Pinocicolin A, an Antibiotic Isocyanide Metabolite Produced by Penicillium pinophilum	11
Xylochemical Synthesis and Biological Evaluation of the Orchidaceous Natural Products Isoarundinin I, Bleochrin F, Blestanol K, and Pleionol	11
Divergent Biosynthesis of Bridged Polycyclic Sesquiterpenoids by a Minimal Fungal Biosynthetic Gene Cluster	11
(±)-Feionemycin A and Chromonemycins A–D, Rearranged Aromatic Polyketides Uncovered by Type II Polyketide Gene Cluster Expression	11
Antimicrobial Polyketides from the Marine-Derived Fungus Spiromastix sp. SCSIO F190	11
Discovery and Heterologous Expression of the Soil Metagenome-Derived Lasso Peptide Metanodin with an Unprecedented Ring Structure	11
Cyathstrines A–K, Structurally Diverse Polycyclic Polyoxygenated Cyathane Diterpenoid Xylosides with Antibacterial and Neuroprotective Activities from the Fungus Cyathus striatu	11
Direct Inhibition of BK Channels by Cannabidiol, One of the Principal Therapeutic Cannabinoids Derived from Cannabis sativa	11
HPPO-Derived Meroterpenoids from the Marine-Derived Fungus Penicillium sp. SCSIO 41691	11
Menominin A and B: Cytotoxic Cyclodepsipeptides from the Freshwater Sponge-Associated Cyanobacterium Nostoc sp. UIC 10607	11
Genome Mining Guided Identification of the Metallophore Delftichelin A from Delftia deserti	11
Triplinones A–H: Anti-Inflammatory Arylalkenyl α,β-Unsaturated-δ-Lactones Isolated from the Leaves of Australian Rainforest Plant Cryptocarya triplinervis (Lauraceae)	11
Antibacterial and Cytotoxic Decahydrofluorene-Class Alkaloids from the Marine-Derived Fungus Penicillium sp. SCSIO 41512	11
Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses	11
Protecting Group Strategies in Natural Product Biosynthesis	11
Shikimate-Derived Meroterpenoids from the Ascidian-Derived Fungus Amphichorda felina SYSU-MS7908 and Their Anti-Glioma Activity	11
Two O-Methyltransferases Mediate Multiple Methylation Steps in the Biosynthesis of Coumarins in Cnidium monnieri	11
Genome Mining and Molecular Networking Guided Discovery of Embleyamycins A–F, the Calcimycin-Type Polyethers from a Desert-Derived Embleya sp. L77	11
Discovery and Biosynthesis of Indole-Functionalized Metabolites from the Human Blood Bacterium, Paracoccus sanguinis, and Their Anti-Skin Aging Activity	11
Anti-Neuroinflammatory Meroterpenoids from a Chinese Collection of the Brown Alga Sargassum siliquastrum	11
Hydroanthraquinones from Nigrospora sphaerica and Their Anti-inflammatory Activity Uncovered by Transcriptome Analysis	11
Access to Natural and Unnatural 28-Norlupane Endoperoxides by Isayama–Mukaiyama Cobalt-Catalyzed Hydroperoxyl Silylation and Evaluation of Antiplasmodial Activity	11
Structural Revision of a Natural Tetrahydroquinoxaline-6-carboxylic Acid Isolated from Caulis Sinomenii through Total Synthesis of Both the Regioisomers	11
Tistrellabactins A and B Are Photoreactive C-Diazeniumdiolate Siderophores from the Marine-Derived Strain Tistrella mobilis KA081020-065	11
Sesquiterpenoids from Seriphidium transiliense and Their Melanogenic Activity	11
Sulfur-Containing Microbial Natural Products and Their Role in Communal Interactions	11
Serinophospholipids: A Third Type of Natural Phospholipid Discovered in a Thermophilic Bacterium	11
Pattern-Based Genome Mining Guides Discovery of the Antibiotic Indanopyrrole A from a Marine Streptomycete	11
Penicamins A–L, Polyoxygenated Diterpenes from Penicillium camemberti JSB-7212	11
Structural Revision of Tinotufolins from Tinospora crispa Leaves Guided by Empirical Rules and DFT Calculations	11
laeA Gene Introduction Strategy Enabling the Construction of a Prolific Fungal Secondary Metabolite Library	11
Title: DAP-Seq Reveals Cluster-Situated Regulator Control of Numerous Streptomyces Natural Product Biosynthetic Genes	11
Heterologous Expression and Characterization of Estercin A, a Class II Lanthipeptide Derived from Clostridium estertheticum CF016, with Antimicrobial Activity against Clinically Relevant Pathog	11
Cannabichromene (CBC) Shows Matrix-Dependent Thermal Configurational Stability	11
Discovery of Ingenane Diterpenoids from Euphorbia hylonoma as Antiadipogenic Agents	11
Isolation and Structure Determination of cis-OPDA-α-Monoglyceride from Arabidopsis thaliana	11
Elucidating the Mechanism of Metabolism of Cannabichromene by Human Cytochrome P450s	11
Bioactive Arylnaphthalide Lignans from Justicia depauperata	11
Total Syntheses, Absolute Configurations, and Cytotoxicity Evaluation of Ugonstilbenes A, B, and C from the Rhizomes of Helminthostachys zeylanica	10
Alstoboonine, an Ulean-Type Indole Alkaloid from Alstonia boonei Leaves	10
Kynurenine: A Promising Structural Motif for Diverse Biological Active Peptides	10
Sacculatane Diterpenoids from the Liverwort Plagiochila nitens Collected in China	10
Issue Editorial Masthead	10
Isolinderalactone Ameliorates the Pathology of Alzheimer’s Disease by Inhibiting the JNK Signaling Pathway	10
Phomactinine, the First Nitrogen-Bearing Phomactin, Produced by Biatriospora sp. CBMAI 1333	10
Naturally Occurring Partially Reduced Perylenequinones from Fungi	10
Atromentin B, Obtained by Microbial Fermentation and Total Synthesis, Potentiates the Activity of β-Lactams Against Methicillin-Resistant Staphylococcus aureus	10
Isolation and Synthesis of Azuriaplysins A and B, Bromoditerpenes with an α-Methylene Carbonyl from the Sea Hare Aplysia kurodai	10