Immunology Letters

Papers
(The median citation count of Immunology Letters is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Expression of concern: “Interleukin-40 is a promising biomarker associated with type 2 diabetes mellitus risk” [Immunology Letters 254 (2023) 1–5]46
Monocyte chemokine receptors as therapeutic targets in cardiovascular diseases44
Hemin acts as CD36 ligand to activate down-stream signalling to disturb immune responses and cytokine secretion from macrophages44
Mettl14 sustains FOXP3 expression to promote the differentiation and functions of induced-regulatory T cells via the mTOR signaling pathway43
The change of Siglec-9 expression in peripheral blood NK cells of SFTS patients can affect the function of NK cells42
Human T cells show plasticity for direct recognition of xenogeneic dendritic cells41
Mechanistic insights into immunopathogenesis of murine cerebral malaria: Cues from “young” C57BL/6J and BALB/c mice34
PLC-IP3-ORAI pathway participates in the activation of the MRGPRB2 receptor in mouse peritoneal mast cells34
Baseline TGF-β correlates with protection after immunization with Plasmodium falciparum sporozoites in the controlled human malaria infection model32
Editorial Board31
Efferocytosis in lung mucosae: implications for health and disease29
Antibody VH domain sequence analysis by a bioinformatics approach based on electronic amino acid properties may help to predict paratop location28
Rho-kinase inhibitors to deplete age-associated B cells in systemic autoimmunity27
IL-38 in Behçet's disease: Gene expression in bronchoalveolar lavage from patients having pulmonary involvement27
Revisiting a vaccine for psoriasis – Has the code been cracked?25
Elevated regulatory T cells after antibiotic treatment of infectious spondylodiscitis as biomarker of recovery?25
Harnessing immunomodulatory mechanisms of Trichinella spiralis to design novel nanomedical approaches for restoring self-tolerance in autoimmunity24
Triptolide alleviates acute gouty arthritis caused by monosodium urate crystals by modulating macrophage polarization and neutrophil activity23
Editorial Board23
TIPE-2 ameliorates inflammatory bowel disease in mice via inhibiting STAT3 and NF-kB activation23
Targeting the PI3K/Akt/mTOR pathway: A therapeutic strategy in COVID-19 patients23
Autoantibodies and therapeutic antibodies against complement Factor H22
Hyperactive neutrophils infiltrate vital organs of tumor bearing host and contribute to gradual systemic deterioration via upregulated NE, MPO and MMP-9 activity22
The immune suppressive functions of macrophages are impaired in patients with ulcerative colitis21
Global histone modification analysis reveals hypoacetylated H3 and H4 histones in B Cells from systemic lupus erythematosus patients21
Impairment of effector molecules response in diabetes induces susceptibility to Leishmania amazonensis infection21
The occurrence of lupus nephritis is regulated by USP7-mediated JMJD3 stabilization20
Mechanisms underpinning poor antibody responses to vaccines in ageing20
The influence of physical activity level and cytomegalovirus serostatus on the cytokine levels of young individuals20
A novel antibody against the furin cleavage site of SARS-CoV-2 spike protein: Effects on proteolytic cleavage and ACE2 binding20
The Th1/Th2 paradigm: A misrepresentation of helper T cell plasticity19
The evaluation of PD-1 and Tim-3 expression besides their related miRNAs in PBMCs of women with recurrent pregnancy loss19
Adaptive T cell tuning in immune regulation and immunotherapy of autoimmune diseases✰18
Th1 adjuvant ARNAX, in combination with radiation therapy, enhances tumor regression in mouse tumor-implant models18
Neutralization of IL-6 inhibits formation of autoreactive TH17 cells but does not prevent loss of renal function in experimental autoimmune glomerulonephritis18
Study of the mechanism of fibroblast-like synoviocytes-derived exosomes inducing macrophages M1 polarization and CD8+T cells immune regulation ferroptosis and autophagy in rheumatoid arthritis18
Downregulation of DNMT3a expression by RNAi and its effect on NF-κBs expression of thymic epithelial cells17
Dengue virus induces interferon-β by activating RNA sensing pathways in megakaryocytes17
Early appearance of functional plasma cells (CD138+CD98+) in non-immunized neonate mice16
Longitudinal analysis at pre- and post-flare of T peripheral helper and T follicular helper subsets in patients with systemic lupus erythematosus16
Could tolerance to DNA be broken in the gut in systemic lupus erythematosus?15
Molecular pathways in sepsis-induced cardiomyocyte pyroptosis: Novel finding on long non-coding RNA ZFAS1/miR-138–5p/SESN2 axis15
Screening epitope peptides based on a phage-displayed random peptide and peptide microarrays to contribute to improving the diagnostic efficiency of systemic lupus erythematosus14
Vitamin D3 attenuates autoimmune thyroiditis by regulating Th17/Treg cell differentiation via YAP/JAK1/STAT1 axis14
Circ_100395 impedes malignancy and glycolysis in papillary thyroid cancer: Involvement of PI3K/AKT/mTOR signaling pathway14
Strategies to reprogram anti-inflammatory macrophages towards pro-inflammatory macrophages to support cancer immunotherapies14
The mitochondria-targeting antioxidant MitoQ alleviated lipopolysaccharide/ d-galactosamine-induced acute liver injury in mice13
Type 1 Diabetes Brazilian patients exhibit reduced frequency of recent thymic emigrants in regulatory CD4+CD25+Foxp3+T cells13
Polarization of rheumatoid macrophages is regulated by the CDKN2B-AS1/ MIR497/TXNIP axis13
Modulation of oxidized low-density lipoprotein-affected macrophage efferocytosis by mitochondrial calcium uniporter in a murine model13
Could we use PD-1 and PD-L1 expression on lymphocytes and monocytes as predictive markers for prognosis of acute biliary pancreatitis?12
Endoplasmic reticulum stress response in immune cells contributes to experimental autoimmune encephalomyelitis pathogenesis in rats12
Rapamycin delays allograft rejection in obese graft recipients through induction of myeloid-derived suppressor cells11
Robust immunity induced by multi-epitope DnaK peptides, potential vaccine candidates against Salmonella: An in vitro study11
In adult X-CGD patients, regulatory T cells are expanded while activated T cells display a NOX2-independent ROS increase11
Immune system aging and the aging-related diseases in the COVID-19 era11
Real-world effectiveness of original BNT162b2 mRNA COVID-19 against symptomatic Omicron infection among children 5–11 years of age in Brazil: A prospective test-negative design study11
Corrigendum to “IL-21 and IL-21-producing T cells are involved in multiple sclerosis severity and progression” [Immunol. Lett. 216 (2019) 12–20]10
Editorial Board10
Corrigendum to “Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma” [Immunology Letters. Volume 265, February 2024, Pages 16-22]10
Sex-specific remodeling of T-cell compartment with aging: Implications for rat susceptibility to central nervous system autoimmune diseases10
Reassuring humoral and cellular immune responses to SARS-CoV-2 vaccination in participants with systemic sclerosis10
BTN2A2-Ig protein inhibits the differentiation of pathogenic Th17 cells and attenuates EAE in mice9
The effect of abnormal lipid metabolism on immunosenescence of the colonic lamina propria in mice of different ages9
Identification and characterization of circulating and adipose tissue infiltrated CD20+ T cells from subjects with obesity that undergo bariatric surgery9
Role of leukocyte-associated Ig-like receptor-1 in the pathogenesis of Kawasaki disease and coronary artery aneurysms9
PARP1 inactivation increases regulatory T / Th17 cell proportion in intestinal inflammation. Role of HMGB19
Elevated circulating CD19+CD24hiCD38hi B cells display pro-inflammatory phenotype in idiopathic membranous nephropathy9
Proinflammatory S100A9 stimulates TLR4/NF-κB signaling pathways causing enhanced phagocytic capacity of microglial cells9
Long-term monocyte activation after coronary artery bypass grafting: An exploratory prospective observational study9
Science fact vs science fiction: A ChatGPT immunological review experiment gone awry9
Mucosal associated invariant T cells: Powerhouses of the lung8
Synergistic neuroprotective effects of Fingolimod and mesenchymal stem cells (MSC) in experimental autoimmune encephalomyelitis8
Mechanisms of histamine release from mast cells beyond the high affinity IgE receptor in severe chronic spontaneous urticaria8
COVID-19 acute respiratory distress syndrome promotes a specific alternative macrophage polarization8
Inflammatory response-related genes predict prognosis in patients with HNSCC8
Soluble CD137 as a potential biomarker for severe COVID-198
Virus-specific antibody responses in severe acute respiratory syndrome coronavirus 2-infected and vaccinated individuals8
Immunotherapy in treatment of leishmaniasis8
Does atopic dermatitis increase the risk of allergic contact dermatitis?8
The cellular biology of plasma cells: Unmet challenges and opportunities7
Corrigendum to ’ Aged AβPPswe/PS1ΔE9 mice as a useful animal model for studying the link between immunological senescence and diseases’[Immunol Lett. 2024 Feb 12:266:106842]7
Aged AβPPswe/PS1ΔE9 mice as a useful animal model for studying the link between immunological senescence and diseases7
Corrigendum to “BML-111, the lipoxin A4 agonist, modulates VEGF or CoCl2-induced migration, angiogenesis and permeability in tumor-derived endothelial cells”[Immunology Letters 230 (2021) 27–35]7
Corrigendum to “Identification and suppression of epidermal growth factor receptor variant III signaling in fibroblast-like synoviocytes from aggressive rheumatoid arthritis by the mimotope” [Immunolo7
Recent preclinical study offers a promising clue: Role of regulatory T cells as biomarkers in migraine7
Role of G-protein-coupled estrogen receptor in the pathogenesis of chronic asthma7
Corrigendum to “Matrine downregulates IL-33/ST2 expression in the central nervous system of rats with experimental autoimmune encephalomyelitis” [Immunol Lett. 178(2016) 97–104]7
A small molecule inhibitor of caspase-1 inhibits NLRP3 inflammasome activation and pyroptosis to alleviate gouty inflammation6
Serum interleukin-38 and -41 levels as candidate biomarkers in male infertility6
Expression of epidermal growth factor receptor (EGFR) in systemic sclerosis patients (SSc) and gastro-oesophageal reflux disease (GORD)6
The disturbance and clinical significance of B cell and circulating follicular helper T cell subsets in children with primary nephrotic syndrome6
Correlation of serum adenosine deaminase activity with disease activity in patients with primary Sjögren's syndrome6
Elevated CD38 expression characterizes impaired CD8+ T cell immune response in metastatic pleural effusions6
TLR ligand loaded exosome mediated immunotherapy of established mammary Tumor in mice6
Conjugation of human serum albumin and flucloxacillin provokes specific immune response in HLA-B*57:01 transgenic mice6
Obituary for Prof. Reinhold E Schmidt, MD (1951 – 2022)6
A new experimental model to study shrimp allergy6
Mucosal immunology: Tolerance and inflammation at the gut surface6
Immunogenic profiling of Mycobacterium tuberculosis DosR protein Rv0569 reveals its ability to switch on Th1 based immunity6
Disturbance in the reconstitution of distinct T-cell subsets and the incidence of GvHD following allo-HSCT in pediatric patients with non-malignant hematological disorders6
Non-coding RNA and epigenetic regulation in immune cells — Editorial6
IL-1β blockade prevents cell death and mucosal damage of the small intestine in a model of sterile inflammation6
T cell landscape in the microenvironment of human solid tumors5
Metabolic regulation of follicular helper T cell differentiation in a mouse model of lupus5
VRK2 inhibition synergizes with PD-1 blockade to improve T cell responses5
Age-related changes in the TRB and IGH repertoires in healthy adult males and females5
Bothrops jararacussu snake venom decreases CD1d, CD83, and CD86 expression on bone marrow-derived dendritic cells5
Oral probiotic promotes indoleamine 2,3-dioxygenase- and TGF-β–Producing plasmacytoid dendritic cells to initiate protection against type 1 diabetes5
Extreme anaerobic exercise causes reduced cytotoxicity and increased cytokine production by peripheral blood lymphocytes5
Berberine alleviates diabetic retinopathy by regulating the Th17/Treg ratio5
Leveraging microRNAs for cellular therapy5
Pre-infection antibody levels of vaccinated healthcare workers with SARS-CoV-2 breakthrough infection: A nested case-control study5
Targeting plasma cells in systemic autoimmune rheumatic diseases – Promises and pitfalls5
Relevance of autoantibody profile with HLA-DRB1 and -DQB1 alleles in a group of Iranian systemic lupus erythematosus patients5
Characterization of testicular macrophage subpopulations in mice5
Is the immunogenicity of PD-1 blocking antibodies a confounding variable in murine studies?5
Use of recombinant S1 protein with hFc for analysis of SARS-CoV-2 adsorption and evaluation of drugs that inhibit entry into VERO E6 cells5
Enhanced immunoprotection against Acinetobacter baumannii infection: Synergistic effects of Bap and BauA in a murine model5
Diminished T-cell immune responses to SARS-CoV-2 omicron variant after BNT162b2 vaccination5
Platelet dropping, bleeding and new treatment requirements in ITP patients after inactivated COVID-19 vaccination5
Junctional adhesion molecule-A on dendritic cells regulates Th1 differentiation5
CD73 in glioblastoma: Where are we now and what are the future directions?5
The imbalance of circulating monocyte subgroups with a higher proportion of the CD14+CD16+CD163+ phenotype in patients with preeclampsia5
Combining local cryoablation with PD-L1 blockade synergistically eradicates established murine lung cancer by modulating mitochondrial in PD-1+CD8+ T cell5
The onco-immunological implications of Fusobacterium nucleatum in breast cancer5
Allergy is an immune disorder related to a lack of regulation: the gluing role of IL-24
Comparison of effects of multiple adjuvants and immunization routes on the immunogenicity and protection of HSV-2 gD subunit vaccine4
Cataloging circulating CD3+CD56+ NKT-like cells through a series of stimulating (NKG2D and DNAM-1) and inhibitory (PD-1, TIGIT, and Tim-3) immune checkpoint receptors in women diagnosed with precancer4
New monogenic autoinflammatory diseases: 2021 year in review4
YAP1 induces marrow derived suppressor cell recruitment in Chlamydia trachomatis infection4
A brief history of epigenetics4
The intestinal microenvironment shapes macrophage and dendritic cell identity and function4
Single-cell sequencing has revealed a more complex array of thymic epithelial cells4
Vaccine safety in children with genetically confirmed mitochondrial disease4
Editorial Board4
Editorial Board4
Potential contribution of the immune system to the emergence of renal diseases4
Could there be a relationship between type III hypersensitivity reactions and graft rejections?4
GM-CSF distinctly impacts human monocytes and macrophages via ERK1/2-dependent pathways4
Increased circulating PD-1hiCXCR5- peripheral helper T cells are associated with disease severity of active ulcerative colitis patients4
Dynamic role of macrophage CX3CR1 expression in inflammatory bowel disease4
NK cell receptors in anti-tumor and healthy tissue protection: Mechanisms and therapeutic advances4
Antibodies to expanded virus antigen panels show elevated diagnostic sensitivities in multiple sclerosis and optic neuritis4
Lymphopenic condition enhanced the antitumor immunity of PD-1-knockout T cells mediated by CRISPR/Cas9 system in malignant melanoma4
Heterogeneity of tissue resident memory T cells4
Immunoregulatory properties of melatonin in the humoral immune system: A narrative review4
Benralizumab reduces eosinophils and inflammatory markers in patients with severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps: A pilot real-life study.4
Could anti-ACE2 antibodies alter the results of SARS-CoV-2 Ab neutralization assays?4
Recombinant MUC1-MBP fusion protein combined with CpG2006 vaccine induces antigen-specific CTL responses through cDC1-mediated cross-priming mainly regulated by type I IFN signaling in mice4
Immunothrombosis biomarkers as potential predictive factors of acute respiratory distress syndrome in moderate-to-critical COVID-19: A single-center, retrospective cohort study4
Mettl3/Ythdf2 regulate macrophage inflammation and ROS generation by controlling Pyk2 mRNA stability4
Isolation of CD35+ follicular dendritic cells and its role in the differentiation from B cells to IgA+GL7+ cells4
Autophagy and LC3-associated phagocytosis contribute negatively to the killing capability of THP-1-derived macrophages against Candida albicans at the mid-stage4
Complement System in Alcohol-Associated Liver Disease4
Overexpression of pigment epithelium-derived factor in breast cancer cell-derived exosomes induces M1 polarization in macrophages4
Dairy starters and fermented dairy products modulate gut mucosal immunity4
Different effectiveness of fungal pathogen-associated molecular patterns (PAMPs) in activating rat peritoneal mast cells3
Silencing TRIM8 alleviates allergic asthma and suppressing Th2 differentiation through inhibiting NF-κB/NLRP3 signaling pathway3
Immune communication between the intestinal microbiota and the cardiovascular system3
Pathogen infection routes and host innate immunity: Lessons from insects3
Distorted frequency and functionality of natural killer cells in pemphigus vulgaris: A potential therapeutic target3
Sphingosylphosphorylcholine ameliorates experimental sjögren's syndrome by regulating salivary gland inflammation and hypofunction, and regulatory B cells3
Acute and prolonged effects of interleukin-33 on cytokines in human cord blood-derived mast cells3
Aloe-emodin relieves allergic contact dermatitis pruritus by inhibiting mast cell degranulation3
A flow cytometric approach to study glucocorticoid receptor expression in immune cell subpopulations of genetically engineered mice3
Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner3
The modulatory effect of crotoxin and its phospholipase A2 subunit from Crotalus durissus terrificus venom on dendritic cells interferes with the generation of effector CD4+ T lymphocytes3
Corrigendum to “Metformin inhibits the pathogenic functions of AChR-specifc B and Th17 cells by targeting miR-146a” [Immunology Letters 250 (2022) 29–40 on Sep 13, 2022/ Manuscript ID: IMLET-D-22-00153
Ageing of T-dependent B cell responses3
Weller et al., T-independent responses to polysaccharides in humans mobilize marginal zone B cells pre-diversified against gut bacterial antigens3
Determination of the transcriptional level of long non-coding RNA NEAT-1, downstream target microRNAs, and genes targeted by microRNAs in diabetic neuropathy patients3
Separating the wheat from the chaff: Making sense of Treg heterogeneity for better adoptive cellular therapy3
Functions of NK and iNKT cells in pediatric and adult CVID, ataxia telangiectasia and agammaglobulinemia patients3
Immunomodulation by heavy metals as a contributing factor to inflammatory diseases and autoimmune reactions: Cadmium as an example3
Gene therapy strategies for RAG1 deficiency: Challenges and breakthroughs3
Benzo[a]pyrene exposure causes exonal switch resulting in reduced surface CD5 expression in an AHR-dependent manner3
Alterations of B-Cell subsets in Peripheral Blood from Adult Patients with Idiopathic Membranous Nephropathy3
Single-cell communication patterns and their intracellular information flow in synovial fibroblastic osteoarthritis and rheumatoid arthritis3
Metformin inhibits the pathogenic functions of AChR-specific B and Th17 cells by targeting miR-146a3
Rheumatoid arthritis autologous synovial fluid affects the plasticity and function of peripheral and induced T regulatory cells in vitro3
Emerging roles for RNA-binding proteins in T lymphocytes3
Filarial infections compromise influenza vaccination efficacy: Lessons from the mouse3
HLA class II peptide-binding-region analysis reveals funneling of polymorphism in action3
Soluble CTLA-4 – A confounding factor in CTLA-4 based checkpoint immunotherapy in cancer3
New aspects in the regulation of human B cell functions by complement receptors CR1, CR2, CR3 and CR42
Reduced EO771-induced tumour growth and increased overall-survival of mice ablated for immune cell-specific catalytic subunit Cβ2 of protein kinase A2
X-ray irradiation reduces ATP-dependent activation of NLRP3 inflammasome by inhibiting TWIK2 activity in macrophages2
Potential utility of calculated globulin as a screening tool for antibody deficiency in children2
OVOL2 inhibits macrophage M2 polarization by regulating IL-10 transcription, and thus inhibits the tumor metastasis by modulating the tumor microenvironment2
Title: Immune-checkpoint inhibitor therapy is underutilized in the US: A multi-institutional cohort analysis2
The role of IgA in gastrointestinal helminthiasis: A systematic review2
Brain-resident regulatory T cells and their role in health and disease2
Prognostic value of CD163+ macrophages in solid tumor malignancies: A scoping review2
Asthma, obesity, and microbiota: A complex immunological interaction2
The oncolytic virus VT09X optimizes immune checkpoint therapy in low immunogenic melanoma2
Inflammasomes in dendritic cells: Friend or foe?2
The phagocytosis dysfunction in lupus nephritis is related to monocyte/macrophage CPT1a2
On immunostimulants and dendritic cell activation2
In virto priming of the STING signaling pathway enhances the maturation and activation of dendritic cells induced by hepatitis B vaccine2
Pitfalls in establishing mouse model of female infertility by immunization with human centromere protein2
Dendritic cells in energy balance regulation2
Interstitial lung disease progression in patients with anti-aminoacyl transfer-RNA-synthetase autoantibodies is characterized by higher levels of sCD1632
A blinded multicenter investigation: Accentuated NK lymphocyte CD335 (NKp46) expression predicts reproductive failures after IVF.2
The MALAT1-H19/miR-19b-3p axis can be a fingerprint for diabetic neuropathy2
A fresh look at a neglected regulatory lineage: CD8+Foxp3+ Regulatory T cells2
Editorial Board2
Does infection with Leishmania protect against Covid-19?2
Synergistic regulation of microglia differentiation by CD93 and integrin β1 in the rat pneumococcal meningitis model2
B cells as target for immunotherapy in rheumatic diseases – current status2
Evaluation of an attenuated Listeria monocytogenes as a vaccine vector to control Helicobacter pylori infection2
Neutrophils-typical atypical antigen presenting cells?2
IL-10 producing B cells regulated 1,3-β-glucan induced Th responses in coordinated with Treg2
Phosphatidylserine promotes immunotherapy for airway allergy2
Single Cell Multiomic Approaches to Disentangle T Cell Heterogeneity2
Inflammatory status might direct ILC and NK cells to IL-17 expressing ILC3 and NK subsets in Behcet's disease2
GILT in tumor cells improves T cell-mediated anti-tumor immune surveillance2
T follicular cells: The regulators of germinal center homeostasis2
IgD−CD27− double negative (DN) B cells: Origins and functions in health and disease2
Pathophysiology of cutaneous T-cell lymphomas: Perspective from a French referral centre2
MiR-30a-3p ameliorates oxidative stress in rheumatoid arthritis synovial fibroblasts via activation of Nrf2-ARE signaling pathway2
Thymocyte migration and emigration2
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