TRAC-Trends in Analytical Chemistry

Article	Citations
Applications of thread-based microfluidics: Approaches and options for detection	442
Editorial Board	288
Editorial	242
Unique role of molecular imaging probes for viral infection	192
Single-cell spatial (scs) omics: Recent developments in data analysis	183
A comprehensive review on ecological effects of microplastic pollution: An interaction with pollutants in the ecosystems and future perspectives	183
CRISPR/Cas system for real-time water quality monitoring: Advances and challenges	183
High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations	176
Nanofibers prepared from synthetic polymers and biopolymers as advanced extraction materials for sample preparation prior to liquid chromatography	174
Toxicity mechanisms and alleviation strategies of micro/nanoplastics to animals: A review	172
Molecularly imprinted polymer-modified carbon paste electrodes (MIP-CPE): A review on sensitive electrochemical sensors for pharmaceutical determinations	168
High-throughput mass spectrometry imaging of biological systems: Current approaches and future directions	163
Recent advances in cell membrane-coated technology for drug discovery from natural products	159
From exogenous to endogenous: Advances in in vivo sampling in living systems	158
Concomitant presence of nanosized plastics and metal(loid)s: is there cause for alarm? State-of-the-art and recommendations for future studies	156
Advances in imaging techniques for real-time microbial visualization in wastewater treatment reactors: Challenges, applications, and process optimization	152
Detection and impact assessment of polylactic acid microplastics in aquatic and sediment systems: Advances in analytical techniques	141
Editorial Board	141
High resolution single-cell transcriptomics towards precision profiling across multi-omics and spatial dimensions	133
Multidimensional single-cell analysis: Diverse strategies and emerging applications in the life sciences	131
Emergent analytical strategies and tools to track functional inorganic nanomaterials applied for sustainable agriculture	129
Galectins detection for the diagnosis of chronic diseases: An emerging biosensor approach	128
Hydroxyapatite-based composites as efficient sorbents: Fabrication and application in sample preparation techniques	127
Advancing cancer diagnosis through surface plasmon resonance detection of extracellular vesicles	123
Mapping micro(nano)plastics in various organ systems: Their emerging links to human diseases?	122

Next-generation point-of-care diagnostics for cervical cancer: Integrating programmable biorecognition, nanomaterials, and artificial intelligence	121
Genetically encoded fluorescent neurotransmitter sensors: A new frontier in molecular diagnostics and real-time brain imaging	119
Advances in optical devices for the detection of contaminants in food and water	118
Advance on the sample preparation and analytical methods for water disinfection byproducts	116
Synthesis strategies to bring molecularly imprinted polymers closer to applications	115
High-throughput optical assays for sensing serine hydrolases in living systems and their applications	113
Electrochemical sensing of human hormones	112
CRISPR-Cas assisted diagnostics: A broad application biosensing approach	111
Microneedle wearables in advanced microsystems: Unlocking next-generation biosensing with AI	111
Optical biosensors utilising viral receptors ACE2 and ACE2 mimics	109
Greenness of analytical methods for the study of metal-containing nanoparticles in biomedical samples, personal care products and food	108
Design strategies and applications of responsive metal-based luminescence probes in the bioanalysis	105
Recent developments and future perspectives of chiral liquid chromatography for food safety and quality	104
Advances and challenges in the selective extraction of low molecular weight carbohydrates using ionic liquids and deep eutectic solvents	104
Single-molecule detection-based super-resolution imaging in single-cell analysis: Inspiring progress and future prospects	104
Analytical and biomedical applications of microfluidics in traditional Chinese medicine research	101
Recent advances in ion mobility instrumentation for targeted analysis	100
Sustainable sorbents for dispersive solid-phase extraction in environmental analysis	98
Micro- and nanoscale sensing of volatile organic compounds for early-stage cancer diagnosis	97
Microscale thermophoresis (MST) and spectral shift (SpS) in drug discovery	96
Novel developments in capillary electrophoresis miniaturization, sampling, detection and portability: An overview of the last decade	96
Application of machine learning to improve the accuracy of electrochemical sensors: A review	96
Advancements in magnetic aptasensors: Recent progress and future trends in biosensor technology	95
Advances in interferometric sensors for the detection of food contaminants	95
Current issues and perspectives in nanosensors-based artificial olfactory systems for breath diagnostics and environmental exposure monitoring	94
Recent advances in metal–organic frameworks as emerging platforms for immunoassays	94
Playing with biological selectivity: Antimicrobial peptides and bacteriophages-based optical biosensors for pathogenic bacteria detection	94
Recent advancements in biosensors for diagnosis of ovarian cancer: Analytical approaches	93
Applications of nanomaterial-based chemiluminescence sensors in environmental analysis	93
On the road to automation: a comparative review on chemometric strategies for GC-MS data analysis	92
Recent advances in flexible sensors: From sensing materials to detection modes	92
3D printed microfluidics for cell biological applications	90
Advancements in detection techniques for per- and polyfluoroalkyl substances: A comprehensive review	89
Editorial Board	89
Molecular recognition-driven detection of β-Lactoglobulin: Mechanisms, progress and future prospects	88
Synergizing Machine Learning and fluorescent biomolecules: A new era in sensing platforms	88
Recent advances in electrochemical sensing of cocaine: A review	87
Deciphering the research of Micro(nano)plastics: An in-depth bibliometric expedition into ecotoxicological impacts and research trends	86
Recent trends and advancements in electrochemiluminescence biosensors for human virus detection	86
Recent advances in single-entity electrochemistry for metal nanoparticle, nanodroplet, and bio-entity analysis	85
Advances in protein sequencing: Techniques, challenges and prospects	85
Potential applications and challenges of novel ambient ionization mass spectrometric techniques in the emergency care for acute poisoning	85
Fluorogenic toolbox for visualizing protein aggregation: From designing principles to biological application	84
Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery	84
Probing protein higher-order structures by native capillary electrophoresis-mass spectrometry	83
Rediscovering similarity analysis of analytical signal: A not well-known mainstay of chemometrics	83
Ion mobility Mass Spectrometry for Glycomics: Challenges and Opportunities When Met with Artificial Intelligence	83
Exhaled volatile organic compounds and respiratory disease: Recent progress and future outlook	83
Microfluidics for chiral separation of biomolecules	83
Recent advances towards the use of deep eutectic solvents and cyclodextrins in the extraction of food contaminants: From traditional sample pretreatment techniques to green microextraction and beyond	82

MXene-based composites: A new generation material for the sample preparation and pre-concentration of the traces of organic species in environmental samples: A comprehensive review	82
Evolution in understandings of the design, optimization, and application of sorbent-based extraction devices	82
Novel sorptive extraction techniques in bioanalysis evaluated by Blue Applicability Grade Index: The paradigm of fabric phase sorptive extraction and capsule phase microextraction	82
Nanomaterial-based chemiluminescence systems for tracing of reactive oxygen species in biosensors	82
State of the art and perspectives of improving antibody performance in food immunosensors	81
Advancement in exosome isolation and label-free detection towards clinical diagnosis	81
The multipurpose application of resazurin in micro-analytical techniques: Trends from the microbial, catalysis and single molecule detection assays	80
Microplastic aging processes: Environmental relevance and analytical implications	80
Recent advancements in polyaniline-based biosensors for diagnosis of cancers: A comprehensive review	80
Trends in electrochemical nanosensors for the analysis of antioxidants	79
Comprehensive approaches to expanding CRISPR biosensor applications beyond nucleic acid targets	79
Recent developments of small-molecule fluorescent probes for the detection of hydroxyl radical in biological systems	79
Emerging single-cell microfluidic technology for microbiology	79
Smart materials as modifiers of capillary electromigration methods in bioanalysis	79
Fluorescent nanozymes: Emerging versatile materials advancing analytical chemistry	79
Optical microscopic and spectroscopic detection of exosomes	78
Neonatal point-of-care testing	78
Recent advances on graphene and graphene oxide as extraction materials in solid-phase (micro)extraction	78
Hydrogel sorbent-based sample preparation processes as green alternatives for the extraction of organic contaminants followed by chromatographic analysis	78
Recent developments in sample pretreatment techniques for the determination of fluoroquinolones in foods	77
Direct RNA modification mapping: Technological advances, gaps, and emerging trends	76
Tracing per- and polyfluoroalkyl substances (PFASs) in the aquatic environment: Target analysis and beyond	75
Analytical performance of electrochemical surface-enhanced Raman spectroscopy: A critical review	75
Cellulose immobilization strategies for paper-based immunoassays	74
Analytical methods for biomonitoring organic chemical hazards in saliva: A systematic review	73
A critical review of acrylamide green extraction and determination in food matrices: Current insights and future perspectives	72
Towards clinical application: Emerging strategies for ultrasensitive and selective miRNA detection	72
Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19	72
Fluorescent sensors for anthelmintic drug detection: Advances in materials, mechanisms, and analytical applications	72
Recent chemical mixing devices for time-resolved serial femtosecond crystallography	72
Boosting comprehensive two-dimensional chromatography with artificial intelligence: Application to food-omics	71
Critical review of analytical methods for antifouling paint particles in marine systems	71
Covalent organic frameworks for next-generation biomedicine: from rational design to multimodal theranostics	71
Recent advances in centrifugal microfluidic chip-based loop-mediated isothermal amplification	70
Machine learning-assisted carbon dots synthesis and analysis: State of the art and future directions	70
The highest yield, or greener solvents? Latest trends in quercetin extraction methods	70
Innovative nanozyme-based detection methods for biomarkers in interstitial fluid	69
Single-molecule microscopy for precision medicine and diagnostics	69
Advancements of multiple template-based molecularly imprinted polymers (mt-MIPs) in deep eutectic solvents (DESs): Towards greener imprinting approaches	69
Applications of metal organic frameworks in point of care testing	69
Capillary electrophoresis and Raman: Can we ever expect light at the end of the tunnel?	68
Editorial Board	68
Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry	68
Application of chemometrics and related advanced data handling in chemical separations	68
Towards a harmonized identification scoring system in LC-HRMS/MS based non-target screening (NTS) of emerging contaminants	67
Nanopore sensing: current progress and future challenges tackled by nanofluidic devices	67
Rapid in-situ synthesis of metal organic frameworks for biosensors	67
Metal-organic frameworks as an alternative smart sensing platform for designing molecularly imprinted electrochemical sensors	67
Recent progress in microfluidic biosensors with different driving forces	67
Corrigendum to “Combining chemometrics and paper-based analytical devices for sensing: An overview” [TrAC. Trends Anal. Chem. 164 (2023) 117091]	66
Recent advances in nano/microfabricated substrate platforms and artificial intelligence for practical surface-enhanced Raman scattering-based bioanalysis	66
Microplastics in soil aggregates: Analytical methods, occurrence patterns, impact analyses and removal approaches	66
Advances in detection technologies for RNA m6A modifications and related enzymes: Strategies and applications	65
Recent trends in analytical measures of microplastic in soil and toxicopathological risk assessment in earthworms	65
Trends in melatonin sensing technology for biomedical applications:Precision sleep medicine and beyond	65
Early-diagnosis of major depressive disorder: From biomarkers to point-of-care testing	65
Functional materials and chemicals in electromembrane extraction	65
Will data analytics revolution finally bring SERS to the clinic?	64
Magnetic-based microextraction systems for the determination of emerging contaminants in environmental liquid samples	64
Development of biomimetic phospholipid membrane chromatography for drug discovery: A comprehensive review	64
The aerobiological pathway of natural respiratory viral aerosols	64
Split technology in CRISPR-Cas system for precision genome manipulation and diagnostics	64
Advances in X-ray neuroimaging: Bridging scales from molecular to organ architectures	63
Green photonic biosensing: Approaching sustainability in point-of-care diagnostics	63
Advances in mass spectrometry-based strategies for analyzing sialic acid linkage isomers	62
Enantioselective separation techniques in forensic analysis and clinical toxicology	62
Emerging ELISA derived technologies for in vitro diagnostics	62
Sample preparation and mass spectrometry for determining mycotoxins, hazardous fungi, and their metabolites in the environment, food, and healthcare	62
Recent advances in droplet microfluidics for single-cell analysis	62
Advances in gas pressure-based portable biosensing	62
Towards a rational and efficient risk assessment for microplastics	61
Recent advance in nucleic acid amplification-based surface-enhanced Raman scattering for in vitro and in vivo biosensing	61
Analytical frontiers in disinfection byproducts research: Linking formation, transformation, and antibiotic resistance through advanced mass spectrometry, isotopic, and sensing tools	61
The interdiscipline rendezvous of aptamers and radionuclides: Advances, challenges and prospects	61
Determination and assessment of contamination of toxic chemical elements in soils – Review	61
Advances in single extracellular vesicle characterization and multiplexed profiling	61
Recent progress and challenges in biosensing of carcinoembryonic antigen	60
Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment	60
Recent advances in metal/covalent organic framework-based materials for photoelectrochemical sensing applications	60
3D printed microfluidics for bioanalysis: A review of recent advancements and applications	60

Recent advancements in dual modality biosensors for detecting disease causing pathogens	60
Recent advances in separation methods for characterization of glutathione metabolism and dietary supplementation	60
Advances in small organic molecule fluorescent probes for formaldehyde detection and imaging in pathophysiological processes: A comprehensive review	59
Editorial Board	59
Recent advances of aptamer based sensors for aflatoxins	59
Nanotechnology-assisted microfluidic systems for chemical sensing, biosensing, and bioanalysis	59
Microplastics and nanoplastics in food, water, and beverages; part I. occurrence	59
Sensitive enzyme-free electrochemical sensors for the detection of pesticide residues in food and water	59
Dual-target fluorescence probes: A new frontier in cardiovascular disease diagnosis	58
Intelligent terahertz data analysis in agriculture: A systematic review of AI-driven approaches	58
Corrigendum to “Molecularly imprinted polymers for the detection of volatile biomarkers” [Trends Anal. Chem. 177 (2024) 117783]	58
Sample preparation of polar metabolites in biological samples: Methodologies and technological insights	58
A review of organic aerosol speciation by comprehensive two-dimensional gas chromatography	58
Caenorhabditis elegans (C. elegans) sample preparation for metabolomics and lipidomics analysis – A review	58
Raman scattering applied to human breath analysis	58
Recent advances in microfluidic devices for foodborne pathogens detection	58
Editorial Board	58
Recent advances in organelle-specific two-photon small-molecule fluorescent probes for bioanalysis in live tissues	58
Membrane inlet mass spectrometry (MIMS) for analysis of water disinfection byproducts: Recent advances	57
Transient OCP-apatite epitaxy controls bone mineralization. An X-ray total scattering study	57
Foodomics in health: Advanced techniques for studying the bioactive role of foods	57
Recent advances of chiral metal-organic frameworks in analytic chemistry	57
Surface-enhanced Raman spectroscopy in the monitoring of drug concentrations in blood	57
Exploiting the penetration depth of XRF and NIR radiation: from 2D to 3D spectral imaging	57
Synthesis and characterization of TiO2 nanomaterials for sensing environmental volatile compounds (VOCs): A review	57
Polymer inclusion membranes based Optode: Recent advances and perspectives	57
Modern sorbent-based sample preparation methods for the determination of analytes of forensic interest: A dual-tool approach for evaluation of greenness and practical utility	56
Deep eutectic solvents for microextraction of endocrine disruptor contaminants from water and food: Review	56
Advances in 3D printed sensors for food analysis	56
Capillary isoelectric focusing – The role of markers of isoelectric point and recent applications in the field	56
Modern automated sample preparation for the determination of organic compounds: A review on robotic and on-flow systems	56
Recent progress in molecular diagnostics: The synergy of rolling circle amplification and CRISPR/Cas systems (2018–2024) – A concise review	56
CRISPR biosensing with lateral flow assays for point of care Diagnostics: Overcoming commercial development challenges	55
Portable X-ray fluorescence (pXRF) as a powerful and trending analytical tool for in situ food samples analysis: A comprehensive review of application - State of the art	55
Recent developments of ECL mechanisms study and their applications	55
Portable sensors in precision agriculture: Assessing advances and challenges in soil nutrient determination	54
Miniaturized solid phase extraction techniques for different kind of pollutants analysis: State of the art and future perspectives – PART 2	54
Minimalist nanobody architecture: A double-edged sword for immunological analysis	54
Development of laser-induced breakdown spectroscopy based spectral tandem technology: A topical review	54
Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics	54
Current trends of unsustainable plastic production and micro(nano)plastic pollution	54
Untargeted chromatographic methods coupled with chemometric strategies for the analysis of food and related samples	54
Trends in nucleic acids and non-nucleic acids nanostructures-enhanced site-specific DNA methylation biosensing	54
Variable electric field and atomic percentage of doping on the displacement process of C20 molecules in a nanotube with molecular dynamics simulation	53
Advances in solid-phase microextraction for detecting endocrine disrupting compounds in environmental and biological matrices	53
Surface molecularly imprinted polymer nanocatalytic probes for scattering spectral analysis	53
Editorial Board	53
The twelve goals of circular analytical chemistry	53
Editorial Board	53
Lateral flow assays for food analyses: Food contaminants, allergens, toxins, and beyond	53
Corrigendum to “Offline preparative separation methods based on electromigration: An overview and current trends” [Trac. Trends Anal. Chem. 170 (2023) 117428]	52
Biosensing based on lossy mode resonances	52
New microextraction techniques in exposome Research: Bridging environmental exposures and human health	52
Update of high-intensity ultrasound applications for the extraction of pectin from agri-food by-products	52
Plasmonic biosensors: Towards fully operative detection platforms for biomedical application and its potential for the diagnosis of autoimmune diseases	51
Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis	51
Editorial Board	51
State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants	51
Recent advances in exhaled breath sample preparation technologies for drug of abuse detection	51
Recent advances in microfluidic single-cell analysis and its applications in drug development	51
From confinement to quantum tunnelling: Redox cycling electrochemistry across scales for ultra-sensitive molecular sensing	51
Current materials for miniaturized sample preparation: Recent advances and future trends	51
Advanced nucleic acid probes for enhanced CRISPR diagnostics	50
Fluorescent probes based on bioorthogonal reactions: Construction strategies and applications	50
MOFs/COFs-based hybrids for agricultural sensors: Current state of art and beyond	50
Polar organic pollutants, micro-nano plastics and nanomaterials: Analytical techniques to reveal the still invisible human physico-chemical exposome	50
Radiometric strategy to track nanopesticides: An important approach to understand the fate, mechanisms of action and toxicity	50
Exploring advanced materials: Harnessing the synergy of inverse gas chromatography and artificial vision intelligence	50
CRISPR/Cas12a-based biosensors for foodborne mycotoxin detection: A review of current technologies and future prospects	50
Deep learning for near-infrared spectral data modelling: Hypes and benefits	50
Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets	49
Multi-scenario deployable analysis platform for the detection of illicit pharmaceutical adulteration in dietary supplements	49
Analysis of contaminants of environment and foods by capillary electromigration techniques	49
Tracking indoor volatile organic compounds with online mass spectrometry	49
Microfluidic trends in drug screening and drug delivery	49
Lights and shadows of mass spectrometry-based metabolomics studies in cancer diagnosis: is there any marker beyond the literature background noise?	49
Deep eutectic solvents-modified advanced functional materials for pollutant detection in food and the environment	49
Recent advances in the analytical applications of laccase-like nanozymes	49
AI-enhanced CRISPR diagnostics: From gRNA design to Cas protein engineering and signal analytics	48
Emerging trends in green carbon dots coated with molecularly imprinted polymers for sensor platforms	48
Plastic problem solved? Environmental implications of synthetic hydrophilic polymers across ecosystem boundaries	48
Recent advances in microfluidic sensors for nutrients detection in water	48
Advances in the analysis of odorous substances derived from drinking water disinfection	48
Uric acid biosensors based on molecular recognition: Classifications, advances, and prospects	48
Gas–phase sampling and preconcentration of nerve agents: Overview of thermally desorbable materials used	48
Forensic drug screening by liquid chromatography hyphenated with high-resolution mass spectrometry (LC-HRMS)	47
Recent advances of cellulose nanofiber-based materials in cell culture: From population to single-cell	47
Ultrasound-assisted microextraction: Advancements, applications, and future directions in analytical chemistry	47
Assessing the availability of trace metals including rare earth elements in deep ocean waters of the Clarion Clipperton Zone, NE Pacific: Application of an in situ DGT passive sampling method	47
Cutting-edge progress in carbon nanomaterial-functionalized silver nanoparticles for enhanced optical and electrochemical sensing applications	47
Laser-scribed micro/nanostructures modified surfaces for electrochemical sensors: From fundamentals to applications	47
Cutting-edge MoS2-Based biosensing platforms for detecting contaminants in food samples	47
The review of nanoplastics in plants: Detection, analysis, uptake, migration and risk	47
Updated overview of QuEChERS applications in food, environmental and biological analysis (2020–2023)	47
Challenges and opportunities in the development of planar potentiometric sensors for point-of-care analysis	47