TRAC-Trends in Analytical Chemistry

Article	Citations
Editorial Board	694
Editorial	472
Editorial Board	287
Applications of thread-based microfluidics: Approaches and options for detection	214
Advance on the sample preparation and analytical methods for water disinfection byproducts	185
Toxicity mechanisms and alleviation strategies of micro/nanoplastics to animals: A review	155
Design strategies and applications of responsive metal-based luminescence probes in the bioanalysis	148
Unique role of molecular imaging probes for viral infection	144
Concomitant presence of nanosized plastics and metal(loid)s: is there cause for alarm? State-of-the-art and recommendations for future studies	143
Advances and challenges in the selective extraction of low molecular weight carbohydrates using ionic liquids and deep eutectic solvents	142
Advances in interferometric sensors for the detection of food contaminants	137
Recent advances in metal–organic frameworks as emerging platforms for immunoassays	135
Mapping micro(nano)plastics in various organ systems: Their emerging links to human diseases?	132
Single-cell spatial (scs) omics: Recent developments in data analysis	132
From exogenous to endogenous: Advances in in vivo sampling in living systems	132
Single-molecule detection-based super-resolution imaging in single-cell analysis: Inspiring progress and future prospects	126
Playing with biological selectivity: Antimicrobial peptides and bacteriophages-based optical biosensors for pathogenic bacteria detection	123
Multidimensional single-cell analysis: Diverse strategies and emerging applications in the life sciences	121
Advances in imaging techniques for real-time microbial visualization in wastewater treatment reactors: Challenges, applications, and process optimization	119
Hydroxyapatite-based composites as efficient sorbents: Fabrication and application in sample preparation techniques	119
Analytical and biomedical applications of microfluidics in traditional Chinese medicine research	117
Galectins detection for the diagnosis of chronic diseases: An emerging biosensor approach	115
Micro- and nanoscale sensing of volatile organic compounds for early-stage cancer diagnosis	115
Advances in optical devices for the detection of contaminants in food and water	113
Mass spectrometry based metabolomics of volume-restricted in-vivo brain samples: Actual status and the way forward	113

3D printed microfluidics for cell biological applications	111
High-throughput mass spectrometry imaging of biological systems: Current approaches and future directions	110
Novel developments in capillary electrophoresis miniaturization, sampling, detection and portability: An overview of the last decade	110
High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations	104
Optical biosensors utilising viral receptors ACE2 and ACE2 mimics	103
Molecularly imprinted polymer-modified carbon paste electrodes (MIP-CPE): A review on sensitive electrochemical sensors for pharmaceutical determinations	100
Recent advances in cell membrane-coated technology for drug discovery from natural products	100
Nanofibers prepared from synthetic polymers and biopolymers as advanced extraction materials for sample preparation prior to liquid chromatography	100
On-line supercritical fluid extraction-supercritical fluid chromatography (SFE-SFC) at a glance: A coupling story	99
Advancements in detection techniques for per- and polyfluoroalkyl substances: A comprehensive review	99
A comprehensive review on ecological effects of microplastic pollution: An interaction with pollutants in the ecosystems and future perspectives	99
Microscale thermophoresis (MST) and spectral shift (SpS) in drug discovery	98
Current issues and perspectives in nanosensors-based artificial olfactory systems for breath diagnostics and environmental exposure monitoring	98
Microneedle wearables in advanced microsystems: Unlocking next-generation biosensing with AI	98
Applications of nanomaterial-based chemiluminescence sensors in environmental analysis	97
Recent developments and future perspectives of chiral liquid chromatography for food safety and quality	97
Greenness of analytical methods for the study of metal-containing nanoparticles in biomedical samples, personal care products and food	96
CRISPR-Cas assisted diagnostics: A broad application biosensing approach	95
High-throughput optical assays for sensing serine hydrolases in living systems and their applications	94
Advancements in magnetic aptasensors: Recent progress and future trends in biosensor technology	93
Recent advances in flexible sensors: From sensing materials to detection modes	93
Recent advancements in biosensors for diagnosis of ovarian cancer: Analytical approaches	93
Deciphering the research of Micro(nano)plastics: An in-depth bibliometric expedition into ecotoxicological impacts and research trends	92
Electrochemical sensing of human hormones	92
A critical review of acrylamide green extraction and determination in food matrices: Current insights and future perspectives	89
Emerging single-cell microfluidic technology for microbiology	88
Bio-inspired approaches for explosives detection	88
Tracing per- and polyfluoroalkyl substances (PFASs) in the aquatic environment: Target analysis and beyond	87
Innovative nanozyme-based detection methods for biomarkers in interstitial fluid	87
Editorial Board	87
Microfluidics for chiral separation of biomolecules	86
Fluorogenic toolbox for visualizing protein aggregation: From designing principles to biological application	86
Liquid crystal-based biosensors as lab-on-chip tools: Promising for future on-site detection test kits	86
Comprehensive approaches to expanding CRISPR biosensor applications beyond nucleic acid targets	86
Analytical methods for biomonitoring organic chemical hazards in saliva: A systematic review	85
Recent chemical mixing devices for time-resolved serial femtosecond crystallography	85
Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery	84
Potential applications and challenges of novel ambient ionization mass spectrometric techniques in the emergency care for acute poisoning	84
Probing protein higher-order structures by native capillary electrophoresis-mass spectrometry	83
Exhaled volatile organic compounds and respiratory disease: Recent progress and future outlook	82
Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19	82
Rediscovering similarity analysis of analytical signal: A not well-known mainstay of chemometrics	81
Recent advances in centrifugal microfluidic chip-based loop-mediated isothermal amplification	79
Advancement in exosome isolation and label-free detection towards clinical diagnosis	79
Recent advances in electrochemical sensing of cocaine: A review	78
Recent advances in single-entity electrochemistry for metal nanoparticle, nanodroplet, and bio-entity analysis	78
The multipurpose application of resazurin in micro-analytical techniques: Trends from the microbial, catalysis and single molecule detection assays	78
Fluorescent nanozymes: Emerging versatile materials advancing analytical chemistry	77
Novel sorptive extraction techniques in bioanalysis evaluated by Blue Applicability Grade Index: The paradigm of fabric phase sorptive extraction and capsule phase microextraction	77
Cellulose immobilization strategies for paper-based immunoassays	77

Recent developments of small-molecule fluorescent probes for the detection of hydroxyl radical in biological systems	75
Boosting comprehensive two-dimensional chromatography with artificial intelligence: Application to food-omics	75
Hydrogel sorbent-based sample preparation processes as green alternatives for the extraction of organic contaminants followed by chromatographic analysis	74
Ion mobility Mass Spectrometry for Glycomics: Challenges and Opportunities When Met with Artificial Intelligence	73
Microplastic aging processes: Environmental relevance and analytical implications	72
Trends in electrochemical nanosensors for the analysis of antioxidants	70
Synergizing Machine Learning and fluorescent biomolecules: A new era in sensing platforms	70
Recent advancements in polyaniline-based biosensors for diagnosis of cancers: A comprehensive review	70
Neonatal point-of-care testing	70
Optical microscopic and spectroscopic detection of exosomes	69
Recent trends and advancements in electrochemiluminescence biosensors for human virus detection	68
Recent developments in sample pretreatment techniques for the determination of fluoroquinolones in foods	67
Recent advances on graphene and graphene oxide as extraction materials in solid-phase (micro)extraction	67
Mass spectrometry for structural elucidation and sequencing of carbohydrates	67
Evolution in understandings of the design, optimization, and application of sorbent-based extraction devices	67
The highest yield, or greener solvents? Latest trends in quercetin extraction methods	67
Nanomaterial-based chemiluminescence systems for tracing of reactive oxygen species in biosensors	67
Recent advances towards the use of deep eutectic solvents and cyclodextrins in the extraction of food contaminants: From traditional sample pretreatment techniques to green microextraction and beyond	66
Applications of metal organic frameworks in point of care testing	66
Analytical performance of electrochemical surface-enhanced Raman spectroscopy: A critical review	66
Editorial Board	65
Machine learning-assisted carbon dots synthesis and analysis: State of the art and future directions	65
Recent advances in nano/microfabricated substrate platforms and artificial intelligence for practical surface-enhanced Raman scattering-based bioanalysis	64
Capillary electrophoresis and Raman: Can we ever expect light at the end of the tunnel?	64
Advances in gas pressure-based portable biosensing	64
Early-diagnosis of major depressive disorder: From biomarkers to point-of-care testing	63
Biomedical application of hyperbranched polymers: Recent Advances and challenges	63
Towards a rational and efficient risk assessment for microplastics	62
Microplastics in soil aggregates: Analytical methods, occurrence patterns, impact analyses and removal approaches	62
Towards a harmonized identification scoring system in LC-HRMS/MS based non-target screening (NTS) of emerging contaminants	61
Recent advances in metal/covalent organic framework-based materials for photoelectrochemical sensing applications	61
Corrigendum to “Combining chemometrics and paper-based analytical devices for sensing: An overview” [TrAC. Trends Anal. Chem. 164 (2023) 117091]	61
Metal-organic frameworks as an alternative smart sensing platform for designing molecularly imprinted electrochemical sensors	61
Will data analytics revolution finally bring SERS to the clinic?	61
Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry	61
Enantioselective separation techniques in forensic analysis and clinical toxicology	60
Application of chemometrics and related advanced data handling in chemical separations	60
Recent advances in separation methods for characterization of glutathione metabolism and dietary supplementation	60
Green photonic biosensing: Approaching sustainability in point-of-care diagnostics	60
Determination and assessment of contamination of toxic chemical elements in soils – Review	60
Recent advances of aptamer based sensors for aflatoxins	60
Recent trends in analytical measures of microplastic in soil and toxicopathological risk assessment in earthworms	59
The aerobiological pathway of natural respiratory viral aerosols	59
Advances in X-ray neuroimaging: Bridging scales from molecular to organ architectures	59
Sample preparation and mass spectrometry for determining mycotoxins, hazardous fungi, and their metabolites in the environment, food, and healthcare	59
Development of biomimetic phospholipid membrane chromatography for drug discovery: A comprehensive review	58
Rapid in-situ synthesis of metal organic frameworks for biosensors	58
Functional materials and chemicals in electromembrane extraction	58
Point of care testing of sports biomarkers: Potential applications, recent advances and future outlook	58
Emerging ELISA derived technologies for in vitro diagnostics	57
Recent progress and challenges in biosensing of carcinoembryonic antigen	57
Nanotechnology-assisted microfluidic systems for chemical sensing, biosensing, and bioanalysis	57
Magnetic-based microextraction systems for the determination of emerging contaminants in environmental liquid samples	57
Sensitive enzyme-free electrochemical sensors for the detection of pesticide residues in food and water	57
Microplastics and nanoplastics in food, water, and beverages; part I. occurrence	56
Recent advances in droplet microfluidics for single-cell analysis	56
Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment	56
Editorial Board	56
3D printed microfluidics for bioanalysis: A review of recent advancements and applications	56
Recent progress in microfluidic biosensors with different driving forces	56
In situ solid phase microextraction sampling of analytes from living human objects for mass spectrometry analysis	55
Recent advances in organelle-specific two-photon small-molecule fluorescent probes for bioanalysis in live tissues	55
Raman scattering applied to human breath analysis	55
Membrane inlet mass spectrometry (MIMS) for analysis of water disinfection byproducts: Recent advances	55
Corrigendum to “Molecularly imprinted polymers for the detection of volatile biomarkers” [Trends Anal. Chem. 177 (2024) 117783]	55
Miniaturized solid phase extraction techniques for different kind of pollutants analysis: State of the art and future perspectives – PART 2	55
From untargeted chemical profiling to peak tables – A fully automated AI driven approach to untargeted GC-MS	55
Deep eutectic solvents for microextraction of endocrine disruptor contaminants from water and food: Review	55
Caenorhabditis elegans (C. elegans) sample preparation for metabolomics and lipidomics analysis – A review	55
Polymer inclusion membranes based Optode: Recent advances and perspectives	54
Modern sorbent-based sample preparation methods for the determination of analytes of forensic interest: A dual-tool approach for evaluation of greenness and practical utility	54
Recent progress in molecular diagnostics: The synergy of rolling circle amplification and CRISPR/Cas systems (2018–2024) – A concise review	54
A review of organic aerosol speciation by comprehensive two-dimensional gas chromatography	54
Portable X-ray fluorescence (pXRF) as a powerful and trending analytical tool for in situ food samples analysis: A comprehensive review of application - State of the art	54
Lateral flow assays for food analyses: Food contaminants, allergens, toxins, and beyond	53
CRISPR biosensing with lateral flow assays for point of care Diagnostics: Overcoming commercial development challenges	53
Transient OCP-apatite epitaxy controls bone mineralization. An X-ray total scattering study	53
Single-cell metabolite analysis by electrospray ionization mass spectrometry	52
Recent trends in carbon-based microelectrodes as electrochemical sensors for neurotransmitter detection: A review	52
Foodomics in health: Advanced techniques for studying the bioactive role of foods	52

Recent advances of chiral metal-organic frameworks in analytic chemistry	52
Capillary isoelectric focusing – The role of markers of isoelectric point and recent applications in the field	52
Recent advances in microfluidic devices for foodborne pathogens detection	52
Nanomaterials meet microfluidics: Improved analytical methods and high-throughput synthetic approaches	52
Untargeted chromatographic methods coupled with chemometric strategies for the analysis of food and related samples	51
Recent advances on portable sensing and biosensing assays applied for detection of main chemical and biological pollutant agents in water samples: A critical review	51
Modern automated sample preparation for the determination of organic compounds: A review on robotic and on-flow systems	51
Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics	50
Nanomaterials-based electrochemical sensors and biosensors for the detection of non-steroidal anti-inflammatory drugs	50
Nano-engineered screen-printed electrodes: A dynamic tool for detection of viruses	50
The twelve goals of circular analytical chemistry	50
Development of laser-induced breakdown spectroscopy based spectral tandem technology: A topical review	50
Advances in 3D printed sensors for food analysis	49
Current trends of unsustainable plastic production and micro(nano)plastic pollution	49
State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants	49
Sample preparation of polar metabolites in biological samples: Methodologies and technological insights	49
Portable sensors in precision agriculture: Assessing advances and challenges in soil nutrient determination	49
Editorial Board	49
Synthesis and characterization of TiO2 nanomaterials for sensing environmental volatile compounds (VOCs): A review	49
Editorial Board	49
Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis	48
Corrigendum to “Offline preparative separation methods based on electromigration: An overview and current trends” [Trac. Trends Anal. Chem. 170 (2023) 117428]	48
Radiometric strategy to track nanopesticides: An important approach to understand the fate, mechanisms of action and toxicity	48
Deep eutectic solvents-modified advanced functional materials for pollutant detection in food and the environment	47
Carbon dots based fluorescence methods for the detections of pesticides and veterinary drugs: Response mechanism, selectivity improvement and application	47
Engineered aptamer for the analysis of cells	47
Emerging trends in green carbon dots coated with molecularly imprinted polymers for sensor platforms	47
Thermal shift assay for protein–ligand dissociation constant determination	47
An overview of analytical methods for enantiomeric determination of chiral pollutants in environmental samples and biota	46
Challenges and opportunities in the development of planar potentiometric sensors for point-of-care analysis	46
Advances in the analysis of odorous substances derived from drinking water disinfection	46
Recent progress of gas sensors based on metal oxide composites derived from bimetallic metal-organic frameworks	46
Plastic problem solved? Environmental implications of synthetic hydrophilic polymers across ecosystem boundaries	46
Recent advances in microfluidic sensors for nutrients detection in water	46
Recent advances in technologies toward the development of 2D materials-based electronic noses	46
Staining methodologies for microplastics screening	46
Uric acid biosensors based on molecular recognition: Classifications, advances, and prospects	46
Tracking indoor volatile organic compounds with online mass spectrometry	45
Cutting-edge progress in carbon nanomaterial-functionalized silver nanoparticles for enhanced optical and electrochemical sensing applications	45
Biosensing based on lossy mode resonances	45
Exploring advanced materials: Harnessing the synergy of inverse gas chromatography and artificial vision intelligence	45
Porous material-based sorbent coatings in solid-phase microextraction technique: Recent trends and future perspectives	45
Recent advances of cellulose nanofiber-based materials in cell culture: From population to single-cell	45
Forensic drug screening by liquid chromatography hyphenated with high-resolution mass spectrometry (LC-HRMS)	45
Fluorescent probes based on bioorthogonal reactions: Construction strategies and applications	45
Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets	44
Variable electric field and atomic percentage of doping on the displacement process of C20 molecules in a nanotube with molecular dynamics simulation	44
MOFs/COFs-based hybrids for agricultural sensors: Current state of art and beyond	44
Recent advances in post-column derivatization: Enhancing sensitivity and selectivity in liquid chromatography analysis	44
Update of high-intensity ultrasound applications for the extraction of pectin from agri-food by-products	44
Polar organic pollutants, micro-nano plastics and nanomaterials: Analytical techniques to reveal the still invisible human physico-chemical exposome	44
Advances in nanomaterial-based microfluidic platforms for on-site detection of foodborne bacteria	44
Advancements in screening systems for active ingredients in traditional Chinese medicines using ligand fishing technique	44
Cutting-edge MoS2-Based biosensing platforms for detecting contaminants in food samples	44
Biomarkers in the diagnosis of wounds infection: An analytical perspective	44
Plasmonic biosensors: Towards fully operative detection platforms for biomedical application and its potential for the diagnosis of autoimmune diseases	44
Recent advances in exhaled breath sample preparation technologies for drug of abuse detection	44
Assessing the availability of trace metals including rare earth elements in deep ocean waters of the Clarion Clipperton Zone, NE Pacific: Application of an in situ DGT passive sampling method	44
Perspectives and challenges in extracellular vesicles untargeted metabolomics analysis	44
Microfluidic trends in drug screening and drug delivery	43
Functionalized magnetic nanoparticles as powerful sorbents and stationary phases for the extraction and chromatographic applications	43
Green synthesis and characterization of carbon-based materials for sensitive detection of heavy metal ions	43
The review of nanoplastics in plants: Detection, analysis, uptake, migration and risk	43
Functionalized magnetic nanoparticles for the separation and purification of proteins and peptides	43
Deep learning for near-infrared spectral data modelling: Hypes and benefits	42
Calibration methods in qualitative analysis	42
Recent advances and applications of Bi2S3-based composites in photoelectrochemical sensors and biosensors	42
Updated overview of QuEChERS applications in food, environmental and biological analysis (2020–2023)	42
Microextraction techniques as versatile platforms for sample preparation of disinfection byproducts from aqueous media: Advances and challenges	42
Current materials for miniaturized sample preparation: Recent advances and future trends	42
Recent advances in microfluidic single-cell analysis and its applications in drug development	42
Nucleic acid-aided molecular amplification techniques for food microorganism detection	42
Contribution of supercritical fluid chromatography to serially coupling columns for chiral and achiral separations	41
Detection, characterization and imaging of micro- and nanoparticles in biotic tissues by laser-induced breakdown spectroscopy	41
Human exposure to micro(nano)plastics: Health risks and analysis methods	41
Prospective analytical role of sensors for environmental screening and monitoring	41
Trends in bimetallic nanomaterials and methods for fourth-generation glucose sensors	40
Dual/Multi-responsive fluorogenic probes for multiple analytes in mitochondria: From design to applications	40
Advanced on-site and in vitro signal amplification biosensors for biomolecule analysis	40
Gold nanoparticles conjugated with fluorophore-labeled DNA: Overview of sensing and imaging applications	40
Seeing the invisible: Preparative strategies to visualise elusive molecules using mass spectrometry imaging	40
Reticular sensing materials with aggregation-induced emission characteristics	40
The role of oxylipins and their validation as biomarkers in the clinical context	40
A review on environmental isotope analysis of aquatic micropollutants: Recent advances, pitfalls and perspectives	40
Recent advances in responsive lanthanide-doped luminescence nanoprobes in the near-infrared-II window	40
Micro/nanofluidic-electrochemical biosensors for in situ tumor cell analysis	40
Reducing uncertainty and confronting ignorance about the potential impacts of microplastic on animals: A critical review	40
Polymers modified porous silicon optical (bio)sensors	40
Recent advances in laser-induced breakdown spectroscopy quantification: From fundamental understanding to data processing	40
Review of miniaturized and portable optical emission spectrometry based on microplasma for elemental analysis	40
Recent advances of upconversion nanoparticles-based lateral flow assays for point-of-care testing	39
Recent advances in data-mining techniques for measuring transformation products by high-resolution mass spectrometry	39
Quantification and mapping of RNA modifications	39
CRISPR techniques and potential for the detection and discrimination of SARS-CoV-2 variants of concern	39
Towards sense and sensitivity-based electrochemical biosensors for liquid biopsy-based breast cancer detection	39