TRAC-Trends in Analytical Chemistry

Article	Citations
Advancing cancer diagnosis through surface plasmon resonance detection of extracellular vesicles	819
Optical biosensors utilising viral receptors ACE2 and ACE2 mimics	525
Design strategies and applications of responsive metal-based luminescence probes in the bioanalysis	340
Editorial Board	234
Editorial Board	188
Editorial	164
Concomitant presence of nanosized plastics and metal(loid)s: is there cause for alarm? State-of-the-art and recommendations for future studies	157
Unique role of molecular imaging probes for viral infection	152
Single-molecule detection-based super-resolution imaging in single-cell analysis: Inspiring progress and future prospects	147
Advances in imaging techniques for real-time microbial visualization in wastewater treatment reactors: Challenges, applications, and process optimization	142
Advance on the sample preparation and analytical methods for water disinfection byproducts	142
Greenness of analytical methods for the study of metal-containing nanoparticles in biomedical samples, personal care products and food	141
Recent developments and future perspectives of chiral liquid chromatography for food safety and quality	141
Microscale thermophoresis (MST) and spectral shift (SpS) in drug discovery	135
High-throughput optical assays for sensing serine hydrolases in living systems and their applications	134
Recent advances in metal–organic frameworks as emerging platforms for immunoassays	131
On-line supercritical fluid extraction-supercritical fluid chromatography (SFE-SFC) at a glance: A coupling story	131
Applications of thread-based microfluidics: Approaches and options for detection	129
Advances and challenges in the selective extraction of low molecular weight carbohydrates using ionic liquids and deep eutectic solvents	129
Advancements in detection techniques for per- and polyfluoroalkyl substances: A comprehensive review	123
Nanofibers prepared from synthetic polymers and biopolymers as advanced extraction materials for sample preparation prior to liquid chromatography	123
3D printed microfluidics for cell biological applications	122
Editorial Board	118
High resolution single-cell transcriptomics towards precision profiling across multi-omics and spatial dimensions	117
High-throughput mass spectrometry imaging of biological systems: Current approaches and future directions	115

Advances in optical devices for the detection of contaminants in food and water	114
Advances in interferometric sensors for the detection of food contaminants	113
On the road to automation: a comparative review on chemometric strategies for GC-MS data analysis	111
Multidimensional single-cell analysis: Diverse strategies and emerging applications in the life sciences	106
Galectins detection for the diagnosis of chronic diseases: An emerging biosensor approach	105
Electrochemical sensing of human hormones	104
Micro- and nanoscale sensing of volatile organic compounds for early-stage cancer diagnosis	104
Recent advancements in biosensors for diagnosis of ovarian cancer: Analytical approaches	103
Applications of nanomaterial-based chemiluminescence sensors in environmental analysis	103
Recent advances in flexible sensors: From sensing materials to detection modes	102
Single-cell spatial (scs) omics: Recent developments in data analysis	101
Toxicity mechanisms and alleviation strategies of micro/nanoplastics to animals: A review	100
A comprehensive review on ecological effects of microplastic pollution: An interaction with pollutants in the ecosystems and future perspectives	100
Recent advances in cell membrane-coated technology for drug discovery from natural products	100
Playing with biological selectivity: Antimicrobial peptides and bacteriophages-based optical biosensors for pathogenic bacteria detection	99
Hydroxyapatite-based composites as efficient sorbents: Fabrication and application in sample preparation techniques	97
Microneedle wearables in advanced microsystems: Unlocking next-generation biosensing with AI	95
Molecularly imprinted polymer-modified carbon paste electrodes (MIP-CPE): A review on sensitive electrochemical sensors for pharmaceutical determinations	94
High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations	94
Analytical and biomedical applications of microfluidics in traditional Chinese medicine research	93
CRISPR-Cas assisted diagnostics: A broad application biosensing approach	93
Current issues and perspectives in nanosensors-based artificial olfactory systems for breath diagnostics and environmental exposure monitoring	93
From exogenous to endogenous: Advances in in vivo sampling in living systems	91
Advancements in magnetic aptasensors: Recent progress and future trends in biosensor technology	91
Mapping micro(nano)plastics in various organ systems: Their emerging links to human diseases?	90
Rediscovering similarity analysis of analytical signal: A not well-known mainstay of chemometrics	88
Novel developments in capillary electrophoresis miniaturization, sampling, detection and portability: An overview of the last decade	88
Editorial Board	86
Ion mobility Mass Spectrometry for Glycomics: Challenges and Opportunities When Met with Artificial Intelligence	85
Cellulose immobilization strategies for paper-based immunoassays	85
Advances in protein sequencing: Techniques, challenges and prospects	84
Innovative nanozyme-based detection methods for biomarkers in interstitial fluid	84
Smart materials as modifiers of capillary electromigration methods in bioanalysis	84
State of the art and perspectives of improving antibody performance in food immunosensors	83
Evolution in understandings of the design, optimization, and application of sorbent-based extraction devices	83
Recent advances in electrochemical sensing of cocaine: A review	83
Analytical performance of electrochemical surface-enhanced Raman spectroscopy: A critical review	82
The highest yield, or greener solvents? Latest trends in quercetin extraction methods	80
Exhaled volatile organic compounds and respiratory disease: Recent progress and future outlook	80
Recent developments of small-molecule fluorescent probes for the detection of hydroxyl radical in biological systems	79
Deciphering the research of Micro(nano)plastics: An in-depth bibliometric expedition into ecotoxicological impacts and research trends	79
A critical review of acrylamide green extraction and determination in food matrices: Current insights and future perspectives	78
Potential applications and challenges of novel ambient ionization mass spectrometric techniques in the emergency care for acute poisoning	78
Synergizing Machine Learning and fluorescent biomolecules: A new era in sensing platforms	76
Tracing per- and polyfluoroalkyl substances (PFASs) in the aquatic environment: Target analysis and beyond	76
Probing protein higher-order structures by native capillary electrophoresis-mass spectrometry	75
Microfluidics for chiral separation of biomolecules	74
Fluorescent nanozymes: Emerging versatile materials advancing analytical chemistry	73
Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19	73
Recent trends and advancements in electrochemiluminescence biosensors for human virus detection	73

Hydrogel sorbent-based sample preparation processes as green alternatives for the extraction of organic contaminants followed by chromatographic analysis	73
Trends in electrochemical nanosensors for the analysis of antioxidants	73
The multipurpose application of resazurin in micro-analytical techniques: Trends from the microbial, catalysis and single molecule detection assays	72
Emerging single-cell microfluidic technology for microbiology	71
Recent advances in single-entity electrochemistry for metal nanoparticle, nanodroplet, and bio-entity analysis	71
Analytical methods for biomonitoring organic chemical hazards in saliva: A systematic review	71
Advancement in exosome isolation and label-free detection towards clinical diagnosis	70
Fluorogenic toolbox for visualizing protein aggregation: From designing principles to biological application	70
Recent chemical mixing devices for time-resolved serial femtosecond crystallography	70
Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery	70
Optical microscopic and spectroscopic detection of exosomes	70
Nanomaterial-based chemiluminescence systems for tracing of reactive oxygen species in biosensors	69
Recent developments in sample pretreatment techniques for the determination of fluoroquinolones in foods	69
Microplastic aging processes: Environmental relevance and analytical implications	69
Applications of metal organic frameworks in point of care testing	68
Recent advances towards the use of deep eutectic solvents and cyclodextrins in the extraction of food contaminants: From traditional sample pretreatment techniques to green microextraction and beyond	67
Neonatal point-of-care testing	67
Recent advancements in polyaniline-based biosensors for diagnosis of cancers: A comprehensive review	67
Mass spectrometry for structural elucidation and sequencing of carbohydrates	66
Boosting comprehensive two-dimensional chromatography with artificial intelligence: Application to food-omics	65
Machine learning-assisted carbon dots synthesis and analysis: State of the art and future directions	65
Recent advances in centrifugal microfluidic chip-based loop-mediated isothermal amplification	65
Editorial Board	64
Comprehensive approaches to expanding CRISPR biosensor applications beyond nucleic acid targets	64
Novel sorptive extraction techniques in bioanalysis evaluated by Blue Applicability Grade Index: The paradigm of fabric phase sorptive extraction and capsule phase microextraction	64
Rapid in-situ synthesis of metal organic frameworks for biosensors	64
Recent advances on graphene and graphene oxide as extraction materials in solid-phase (micro)extraction	64
Recent advance in nucleic acid amplification-based surface-enhanced Raman scattering for in vitro and in vivo biosensing	63
Magnetic-based microextraction systems for the determination of emerging contaminants in environmental liquid samples	63
Advances in small organic molecule fluorescent probes for formaldehyde detection and imaging in pathophysiological processes: A comprehensive review	63
Will data analytics revolution finally bring SERS to the clinic?	63
The interdiscipline rendezvous of aptamers and radionuclides: Advances, challenges and prospects	63
Advances in mass spectrometry-based strategies for analyzing sialic acid linkage isomers	63
Advances in X-ray neuroimaging: Bridging scales from molecular to organ architectures	62
Application of chemometrics and related advanced data handling in chemical separations	62
The aerobiological pathway of natural respiratory viral aerosols	62
Capillary electrophoresis and Raman: Can we ever expect light at the end of the tunnel?	62
Corrigendum to “Combining chemometrics and paper-based analytical devices for sensing: An overview” [TrAC. Trends Anal. Chem. 164 (2023) 117091]	61
Early-diagnosis of major depressive disorder: From biomarkers to point-of-care testing	61
Recent advances of aptamer based sensors for aflatoxins	61
Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry	61
Green photonic biosensing: Approaching sustainability in point-of-care diagnostics	61
Advances in gas pressure-based portable biosensing	61
Recent progress and challenges in biosensing of carcinoembryonic antigen	61
Nanotechnology-assisted microfluidic systems for chemical sensing, biosensing, and bioanalysis	60
Development of biomimetic phospholipid membrane chromatography for drug discovery: A comprehensive review	60
Determination and assessment of contamination of toxic chemical elements in soils – Review	60
Microplastics in soil aggregates: Analytical methods, occurrence patterns, impact analyses and removal approaches	60
Recent progress in microfluidic biosensors with different driving forces	60
Recent advances in droplet microfluidics for single-cell analysis	59
Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment	59
Recent trends in analytical measures of microplastic in soil and toxicopathological risk assessment in earthworms	59
Recent advances in separation methods for characterization of glutathione metabolism and dietary supplementation	59
3D printed microfluidics for bioanalysis: A review of recent advancements and applications	59
Sensitive enzyme-free electrochemical sensors for the detection of pesticide residues in food and water	59
Functional materials and chemicals in electromembrane extraction	59
Recent advances in nano/microfabricated substrate platforms and artificial intelligence for practical surface-enhanced Raman scattering-based bioanalysis	59
Enantioselective separation techniques in forensic analysis and clinical toxicology	58
Metal-organic frameworks as an alternative smart sensing platform for designing molecularly imprinted electrochemical sensors	57
Emerging ELISA derived technologies for in vitro diagnostics	57
Towards a harmonized identification scoring system in LC-HRMS/MS based non-target screening (NTS) of emerging contaminants	57
Microplastics and nanoplastics in food, water, and beverages; part I. occurrence	56
Raman scattering applied to human breath analysis	56
Recent advances in metal/covalent organic framework-based materials for photoelectrochemical sensing applications	56
Minimalist nanobody architecture: A double-edged sword for immunological analysis	56
Sample preparation and mass spectrometry for determining mycotoxins, hazardous fungi, and their metabolites in the environment, food, and healthcare	56
Towards a rational and efficient risk assessment for microplastics	56
Trends in nucleic acids and non-nucleic acids nanostructures-enhanced site-specific DNA methylation biosensing	55
Modern sorbent-based sample preparation methods for the determination of analytes of forensic interest: A dual-tool approach for evaluation of greenness and practical utility	55
Surface molecularly imprinted polymer nanocatalytic probes for scattering spectral analysis	55
Corrigendum to “Molecularly imprinted polymers for the detection of volatile biomarkers” [Trends Anal. Chem. 177 (2024) 117783]	55
Editorial Board	54
Capillary isoelectric focusing – The role of markers of isoelectric point and recent applications in the field	54
Recent advances of chiral metal-organic frameworks in analytic chemistry	54
Surface-enhanced Raman spectroscopy in the monitoring of drug concentrations in blood	54
CRISPR biosensing with lateral flow assays for point of care Diagnostics: Overcoming commercial development challenges	54
Polymer inclusion membranes based Optode: Recent advances and perspectives	54
From untargeted chemical profiling to peak tables – A fully automated AI driven approach to untargeted GC-MS	54
Recent progress in molecular diagnostics: The synergy of rolling circle amplification and CRISPR/Cas systems (2018–2024) – A concise review	53
Membrane inlet mass spectrometry (MIMS) for analysis of water disinfection byproducts: Recent advances	53

Sample preparation of polar metabolites in biological samples: Methodologies and technological insights	53
Deep eutectic solvents for microextraction of endocrine disruptor contaminants from water and food: Review	53
Synthesis and characterization of TiO2 nanomaterials for sensing environmental volatile compounds (VOCs): A review	52
Lateral flow assays for food analyses: Food contaminants, allergens, toxins, and beyond	52
Transient OCP-apatite epitaxy controls bone mineralization. An X-ray total scattering study	52
Portable sensors in precision agriculture: Assessing advances and challenges in soil nutrient determination	52
Caenorhabditis elegans (C. elegans) sample preparation for metabolomics and lipidomics analysis – A review	52
Advances in 3D printed sensors for food analysis	52
Recent advances in organelle-specific two-photon small-molecule fluorescent probes for bioanalysis in live tissues	52
A review of organic aerosol speciation by comprehensive two-dimensional gas chromatography	52
Development of laser-induced breakdown spectroscopy based spectral tandem technology: A topical review	51
Miniaturized solid phase extraction techniques for different kind of pollutants analysis: State of the art and future perspectives – PART 2	51
Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics	51
Untargeted chromatographic methods coupled with chemometric strategies for the analysis of food and related samples	51
Recent advances in microfluidic devices for foodborne pathogens detection	51
Dual-target Fluorescence Probes: A New Frontier in Cardiovascular Disease Diagnosis	51
Modern automated sample preparation for the determination of organic compounds: A review on robotic and on-flow systems	51
The twelve goals of circular analytical chemistry	51
Recent trends in carbon-based microelectrodes as electrochemical sensors for neurotransmitter detection: A review	51
Current trends of unsustainable plastic production and micro(nano)plastic pollution	50
Variable electric field and atomic percentage of doping on the displacement process of C20 molecules in a nanotube with molecular dynamics simulation	50
Editorial Board	50
Advances in solid-phase microextraction for detecting endocrine disrupting compounds in environmental and biological matrices	50
Editorial Board	50
Corrigendum to “Offline preparative separation methods based on electromigration: An overview and current trends” [Trac. Trends Anal. Chem. 170 (2023) 117428]	50
Foodomics in health: Advanced techniques for studying the bioactive role of foods	50
Portable X-ray fluorescence (pXRF) as a powerful and trending analytical tool for in situ food samples analysis: A comprehensive review of application - State of the art	50
Uric acid biosensors based on molecular recognition: Classifications, advances, and prospects	49
Plastic problem solved? Environmental implications of synthetic hydrophilic polymers across ecosystem boundaries	49
Advancements in screening systems for active ingredients in traditional Chinese medicines using ligand fishing technique	48
Deep learning for near-infrared spectral data modelling: Hypes and benefits	48
Advances in nanomaterial-based microfluidic platforms for on-site detection of foodborne bacteria	48
Recent advances in microfluidic single-cell analysis and its applications in drug development	48
Polar organic pollutants, micro-nano plastics and nanomaterials: Analytical techniques to reveal the still invisible human physico-chemical exposome	48
Laser-scribed micro/nanostructures modified surfaces for electrochemical sensors: From fundamentals to applications	48
Recent advances in post-column derivatization: Enhancing sensitivity and selectivity in liquid chromatography analysis	48
Carbon dots based fluorescence methods for the detections of pesticides and veterinary drugs: Response mechanism, selectivity improvement and application	47
Radiometric strategy to track nanopesticides: An important approach to understand the fate, mechanisms of action and toxicity	47
MOFs/COFs-based hybrids for agricultural sensors: Current state of art and beyond	47
Forensic drug screening by liquid chromatography hyphenated with high-resolution mass spectrometry (LC-HRMS)	47
State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants	47
Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets	47
Recent advances and applications of Bi2S3-based composites in photoelectrochemical sensors and biosensors	47
Cutting-edge progress in carbon nanomaterial-functionalized silver nanoparticles for enhanced optical and electrochemical sensing applications	47
Challenges and opportunities in the development of planar potentiometric sensors for point-of-care analysis	46
The review of nanoplastics in plants: Detection, analysis, uptake, migration and risk	46
Cutting-edge MoS2-Based biosensing platforms for detecting contaminants in food samples	46
Recent progress of gas sensors based on metal oxide composites derived from bimetallic metal-organic frameworks	46
Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis	46
Update of high-intensity ultrasound applications for the extraction of pectin from agri-food by-products	46
Advances in the analysis of odorous substances derived from drinking water disinfection	46
Plasmonic biosensors: Towards fully operative detection platforms for biomedical application and its potential for the diagnosis of autoimmune diseases	45
Engineered aptamer for the analysis of cells	45
Recent advances in technologies toward the development of 2D materials-based electronic noses	45
Assessing the availability of trace metals including rare earth elements in deep ocean waters of the Clarion Clipperton Zone, NE Pacific: Application of an in situ DGT passive sampling method	45
New microextraction techniques in exposome Research: Bridging environmental exposures and human health	45
Tracking indoor volatile organic compounds with online mass spectrometry	44
Microfluidic trends in drug screening and drug delivery	44
Recent advances in microfluidic sensors for nutrients detection in water	44
Recent advances of cellulose nanofiber-based materials in cell culture: From population to single-cell	44
Biosensing based on lossy mode resonances	44
Recent advances in exhaled breath sample preparation technologies for drug of abuse detection	44
Thermal shift assay for protein–ligand dissociation constant determination	44
Fluorescent probes based on bioorthogonal reactions: Construction strategies and applications	44
Exploring advanced materials: Harnessing the synergy of inverse gas chromatography and artificial vision intelligence	44
Updated overview of QuEChERS applications in food, environmental and biological analysis (2020–2023)	43
Advances on constructing functional reticular materials for efficient determination of radionuclides	43
Recent advances of upconversion nanoparticles-based lateral flow assays for point-of-care testing	43
Gold nanoparticles conjugated with fluorophore-labeled DNA: Overview of sensing and imaging applications	43
Green synthesis and characterization of carbon-based materials for sensitive detection of heavy metal ions	43
Current materials for miniaturized sample preparation: Recent advances and future trends	43
Deep eutectic solvents-modified advanced functional materials for pollutant detection in food and the environment	43
Seeing the invisible: Preparative strategies to visualise elusive molecules using mass spectrometry imaging	43
Distance-based detection in analytical flow devices: From gas detection tubes to microfluidic chips and microfluidic paper-based analytical devices	43
Emerging trends in green carbon dots coated with molecularly imprinted polymers for sensor platforms	43
Staining methodologies for microplastics screening	43
Nanomaterial-based microfluidic systems for cancer biomarker detection: Recent applications and future perspectives	43
Advanced on-site and in vitro signal amplification biosensors for biomolecule analysis	43
Artificial intelligence for method development in liquid chromatography	42
Recent advances in responsive lanthanide-doped luminescence nanoprobes in the near-infrared-II window	42
Smart analytical chemistry: Integrating green, sustainable, white and AI-driven approaches in modern analysis	42
Micro/nanofluidic-electrochemical biosensors for in situ tumor cell analysis	42
Microplastics, heavy metals, antibiotics, and antibiotic resistance genes in recirculating aquaculture systems	42
Nucleic acid-aided molecular amplification techniques for food microorganism detection	42
Review of miniaturized and portable optical emission spectrometry based on microplasma for elemental analysis	42
Quantification and mapping of RNA modifications	42
Calibration methods in qualitative analysis	42
Protein-mediated fluorescent probes for bioimaging and biosensing: From fundamentals to applications	42
Contribution of supercritical fluid chromatography to serially coupling columns for chiral and achiral separations	42
Prospective analytical role of sensors for environmental screening and monitoring	42
Towards sense and sensitivity-based electrochemical biosensors for liquid biopsy-based breast cancer detection	41
CRISPR techniques and potential for the detection and discrimination of SARS-CoV-2 variants of concern	41
Enzyme and nanozyme biosensors based on MOFs for pesticide detection	41
Reducing uncertainty and confronting ignorance about the potential impacts of microplastic on animals: A critical review	41
Dual/Multi-responsive fluorogenic probes for multiple analytes in mitochondria: From design to applications	41