TRAC-Trends in Analytical Chemistry

Article	Citations
Applications of thread-based microfluidics: Approaches and options for detection	897
Editorial Board	554
Editorial Board	379
Editorial	251
Concomitant presence of nanosized plastics and metal(loid)s: is there cause for alarm? State-of-the-art and recommendations for future studies	207
Unique role of molecular imaging probes for viral infection	172
Editorial Board	163
Recent advances in cell membrane-coated technology for drug discovery from natural products	156
Advances in optical devices for the detection of contaminants in food and water	153
Advances in imaging techniques for real-time microbial visualization in wastewater treatment reactors: Challenges, applications, and process optimization	151
Toxicity mechanisms and alleviation strategies of micro/nanoplastics to animals: A review	149
Single-cell spatial (scs) omics: Recent developments in data analysis	145
Single-molecule detection-based super-resolution imaging in single-cell analysis: Inspiring progress and future prospects	144
Recent developments and future perspectives of chiral liquid chromatography for food safety and quality	141
High-throughput mass spectrometry imaging of biological systems: Current approaches and future directions	139
Advancing cancer diagnosis through surface plasmon resonance detection of extracellular vesicles	139
Recent advances in ion mobility instrumentation for targeted analysis	136
Current issues and perspectives in nanosensors-based artificial olfactory systems for breath diagnostics and environmental exposure monitoring	135
High-throughput optical assays for sensing serine hydrolases in living systems and their applications	131
Micro- and nanoscale sensing of volatile organic compounds for early-stage cancer diagnosis	128
Analytical and biomedical applications of microfluidics in traditional Chinese medicine research	126
Novel developments in capillary electrophoresis miniaturization, sampling, detection and portability: An overview of the last decade	124
Optical biosensors utilising viral receptors ACE2 and ACE2 mimics	123
High resolution single-cell transcriptomics towards precision profiling across multi-omics and spatial dimensions	121
Multidimensional single-cell analysis: Diverse strategies and emerging applications in the life sciences	119

CRISPR-Cas assisted diagnostics: A broad application biosensing approach	116
Advance on the sample preparation and analytical methods for water disinfection byproducts	109
Advances and challenges in the selective extraction of low molecular weight carbohydrates using ionic liquids and deep eutectic solvents	109
Microscale thermophoresis (MST) and spectral shift (SpS) in drug discovery	109
Mapping micro(nano)plastics in various organ systems: Their emerging links to human diseases?	107
High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations	107
From exogenous to endogenous: Advances in in vivo sampling in living systems	105
Recent advances in metal–organic frameworks as emerging platforms for immunoassays	105
3D printed microfluidics for cell biological applications	103
Galectins detection for the diagnosis of chronic diseases: An emerging biosensor approach	102
Advancements in detection techniques for per- and polyfluoroalkyl substances: A comprehensive review	101
Microneedle wearables in advanced microsystems: Unlocking next-generation biosensing with AI	99
Greenness of analytical methods for the study of metal-containing nanoparticles in biomedical samples, personal care products and food	99
Playing with biological selectivity: Antimicrobial peptides and bacteriophages-based optical biosensors for pathogenic bacteria detection	98
Advances in interferometric sensors for the detection of food contaminants	96
Recent advancements in biosensors for diagnosis of ovarian cancer: Analytical approaches	95
Application of machine learning to improve the accuracy of electrochemical sensors: A review	94
Molecularly imprinted polymer-modified carbon paste electrodes (MIP-CPE): A review on sensitive electrochemical sensors for pharmaceutical determinations	91
Design strategies and applications of responsive metal-based luminescence probes in the bioanalysis	90
Recent advances in flexible sensors: From sensing materials to detection modes	89
A comprehensive review on ecological effects of microplastic pollution: An interaction with pollutants in the ecosystems and future perspectives	88
Hydroxyapatite-based composites as efficient sorbents: Fabrication and application in sample preparation techniques	88
Nanofibers prepared from synthetic polymers and biopolymers as advanced extraction materials for sample preparation prior to liquid chromatography	88
Electrochemical sensing of human hormones	87
Applications of nanomaterial-based chemiluminescence sensors in environmental analysis	87
On the road to automation: a comparative review on chemometric strategies for GC-MS data analysis	87
Advancements in magnetic aptasensors: Recent progress and future trends in biosensor technology	87
Microfluidics for chiral separation of biomolecules	86
Editorial Board	86
Advances in analytical technologies detecting and characterizing noncovalent interactions for fragment-based drug discovery	85
Recent chemical mixing devices for time-resolved serial femtosecond crystallography	85
Fluorogenic toolbox for visualizing protein aggregation: From designing principles to biological application	85
Potential applications and challenges of novel ambient ionization mass spectrometric techniques in the emergency care for acute poisoning	84
Probing protein higher-order structures by native capillary electrophoresis-mass spectrometry	83
Analytical performance of electrochemical surface-enhanced Raman spectroscopy: A critical review	82
Ion mobility Mass Spectrometry for Glycomics: Challenges and Opportunities When Met with Artificial Intelligence	81
Analytical methods for biomonitoring organic chemical hazards in saliva: A systematic review	81
Synergizing Machine Learning and fluorescent biomolecules: A new era in sensing platforms	80
Advances in protein sequencing: Techniques, challenges and prospects	80
Direct RNA modification mapping: Technological advances, gaps, and emerging trends	80
Neonatal point-of-care testing	78
Emerging single-cell microfluidic technology for microbiology	78
Evolution in understandings of the design, optimization, and application of sorbent-based extraction devices	77
State of the art and perspectives of improving antibody performance in food immunosensors	77
Recent trends and advancements in electrochemiluminescence biosensors for human virus detection	77
Fluorescent sensors for anthelmintic drug detection: Advances in materials, mechanisms, and analytical applications	74
Fluorescent nanozymes: Emerging versatile materials advancing analytical chemistry	74
Recent advances in centrifugal microfluidic chip-based loop-mediated isothermal amplification	73
Tracing per- and polyfluoroalkyl substances (PFASs) in the aquatic environment: Target analysis and beyond	73
Applications of metal organic frameworks in point of care testing	72

Exhaled volatile organic compounds and respiratory disease: Recent progress and future outlook	72
Cellulose immobilization strategies for paper-based immunoassays	72
Advancement in exosome isolation and label-free detection towards clinical diagnosis	72
Recent developments of small-molecule fluorescent probes for the detection of hydroxyl radical in biological systems	72
Innovative nanozyme-based detection methods for biomarkers in interstitial fluid	72
Optical microscopic and spectroscopic detection of exosomes	72
MXene-based composites: A new generation material for the sample preparation and pre-concentration of the traces of organic species in environmental samples: A comprehensive review	71
Recent advancements in polyaniline-based biosensors for diagnosis of cancers: A comprehensive review	71
Trends in electrochemical nanosensors for the analysis of antioxidants	71
Machine learning-assisted carbon dots synthesis and analysis: State of the art and future directions	70
Recent advances in single-entity electrochemistry for metal nanoparticle, nanodroplet, and bio-entity analysis	70
The multipurpose application of resazurin in micro-analytical techniques: Trends from the microbial, catalysis and single molecule detection assays	70
A critical review of acrylamide green extraction and determination in food matrices: Current insights and future perspectives	69
Boosting comprehensive two-dimensional chromatography with artificial intelligence: Application to food-omics	69
Recent developments in sample pretreatment techniques for the determination of fluoroquinolones in foods	69
Smart materials as modifiers of capillary electromigration methods in bioanalysis	69
Recent advances on graphene and graphene oxide as extraction materials in solid-phase (micro)extraction	68
The highest yield, or greener solvents? Latest trends in quercetin extraction methods	68
Hydrogel sorbent-based sample preparation processes as green alternatives for the extraction of organic contaminants followed by chromatographic analysis	68
Nanomaterial-based chemiluminescence systems for tracing of reactive oxygen species in biosensors	68
Deciphering the research of Micro(nano)plastics: An in-depth bibliometric expedition into ecotoxicological impacts and research trends	68
Rediscovering similarity analysis of analytical signal: A not well-known mainstay of chemometrics	67
Recent advances in electrochemical sensing of cocaine: A review	67
Comprehensive approaches to expanding CRISPR biosensor applications beyond nucleic acid targets	67
Novel sorptive extraction techniques in bioanalysis evaluated by Blue Applicability Grade Index: The paradigm of fabric phase sorptive extraction and capsule phase microextraction	66
Molecular recognition-driven detection of β-Lactoglobulin: Mechanisms, progress and future prospects	66
Recent advances towards the use of deep eutectic solvents and cyclodextrins in the extraction of food contaminants: From traditional sample pretreatment techniques to green microextraction and beyond	66
Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19	66
Microplastic aging processes: Environmental relevance and analytical implications	66
Advances in X-ray neuroimaging: Bridging scales from molecular to organ architectures	65
Application of chemometrics and related advanced data handling in chemical separations	65
Rapid in-situ synthesis of metal organic frameworks for biosensors	65
Corrigendum to “Combining chemometrics and paper-based analytical devices for sensing: An overview” [TrAC. Trends Anal. Chem. 164 (2023) 117091]	65
Editorial Board	65
Capillary electrophoresis and Raman: Can we ever expect light at the end of the tunnel?	65
3D printed microfluidics for bioanalysis: A review of recent advancements and applications	64
Advances in gas pressure-based portable biosensing	64
Recent trends in analytical measures of microplastic in soil and toxicopathological risk assessment in earthworms	64
Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment	64
Development of biomimetic phospholipid membrane chromatography for drug discovery: A comprehensive review	64
Green photonic biosensing: Approaching sustainability in point-of-care diagnostics	63
Enantioselective separation techniques in forensic analysis and clinical toxicology	63
Towards a rational and efficient risk assessment for microplastics	63
Recent advances in nano/microfabricated substrate platforms and artificial intelligence for practical surface-enhanced Raman scattering-based bioanalysis	63
Functional materials and chemicals in electromembrane extraction	63
Emerging ELISA derived technologies for in vitro diagnostics	62
Nanopore sensing: current progress and future challenges tackled by nanofluidic devices	62
Will data analytics revolution finally bring SERS to the clinic?	62
Recent advances in separation methods for characterization of glutathione metabolism and dietary supplementation	62
Advances in small organic molecule fluorescent probes for formaldehyde detection and imaging in pathophysiological processes: A comprehensive review	61
Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry	61
Recent advance in nucleic acid amplification-based surface-enhanced Raman scattering for in vitro and in vivo biosensing	61
Advances in mass spectrometry-based strategies for analyzing sialic acid linkage isomers	61
The interdiscipline rendezvous of aptamers and radionuclides: Advances, challenges and prospects	60
Nanotechnology-assisted microfluidic systems for chemical sensing, biosensing, and bioanalysis	60
Recent progress and challenges in biosensing of carcinoembryonic antigen	60
The aerobiological pathway of natural respiratory viral aerosols	59
Sample preparation and mass spectrometry for determining mycotoxins, hazardous fungi, and their metabolites in the environment, food, and healthcare	58
Early-diagnosis of major depressive disorder: From biomarkers to point-of-care testing	58
Recent advances of aptamer based sensors for aflatoxins	58
Microplastics and nanoplastics in food, water, and beverages; part I. occurrence	58
Determination and assessment of contamination of toxic chemical elements in soils – Review	57
Recent advances in metal/covalent organic framework-based materials for photoelectrochemical sensing applications	57
Sensitive enzyme-free electrochemical sensors for the detection of pesticide residues in food and water	57
Recent advancements in dual modality biosensors for detecting disease causing pathogens	57
Recent advances in droplet microfluidics for single-cell analysis	57
Microplastics in soil aggregates: Analytical methods, occurrence patterns, impact analyses and removal approaches	57
Recent progress in microfluidic biosensors with different driving forces	56
Raman scattering applied to human breath analysis	56
Magnetic-based microextraction systems for the determination of emerging contaminants in environmental liquid samples	56
Metal-organic frameworks as an alternative smart sensing platform for designing molecularly imprinted electrochemical sensors	56
Towards a harmonized identification scoring system in LC-HRMS/MS based non-target screening (NTS) of emerging contaminants	56
Corrigendum to “Molecularly imprinted polymers for the detection of volatile biomarkers” [Trends Anal. Chem. 177 (2024) 117783]	56
Editorial Board	55
Editorial Board	55
Polymer inclusion membranes based Optode: Recent advances and perspectives	55
Minimalist nanobody architecture: A double-edged sword for immunological analysis	55
Recent advances of chiral metal-organic frameworks in analytic chemistry	55
Capillary isoelectric focusing – The role of markers of isoelectric point and recent applications in the field	55
Dual-target fluorescence probes: A new frontier in cardiovascular disease diagnosis	55

Deep eutectic solvents for microextraction of endocrine disruptor contaminants from water and food: Review	54
A review of organic aerosol speciation by comprehensive two-dimensional gas chromatography	54
Trends in nucleic acids and non-nucleic acids nanostructures-enhanced site-specific DNA methylation biosensing	54
Recent advances in organelle-specific two-photon small-molecule fluorescent probes for bioanalysis in live tissues	54
Surface molecularly imprinted polymer nanocatalytic probes for scattering spectral analysis	53
Transient OCP-apatite epitaxy controls bone mineralization. An X-ray total scattering study	53
Recent advances in microfluidic devices for foodborne pathogens detection	53
Lateral flow assays for food analyses: Food contaminants, allergens, toxins, and beyond	53
Surface-enhanced Raman spectroscopy in the monitoring of drug concentrations in blood	53
Miniaturized solid phase extraction techniques for different kind of pollutants analysis: State of the art and future perspectives – PART 2	53
Recent developments of ECL mechanisms study and their applications	53
Foodomics in health: Advanced techniques for studying the bioactive role of foods	53
The twelve goals of circular analytical chemistry	53
Sample preparation of polar metabolites in biological samples: Methodologies and technological insights	53
Current trends of unsustainable plastic production and micro(nano)plastic pollution	52
Portable X-ray fluorescence (pXRF) as a powerful and trending analytical tool for in situ food samples analysis: A comprehensive review of application - State of the art	52
Development of laser-induced breakdown spectroscopy based spectral tandem technology: A topical review	52
Membrane inlet mass spectrometry (MIMS) for analysis of water disinfection byproducts: Recent advances	52
Modern automated sample preparation for the determination of organic compounds: A review on robotic and on-flow systems	52
Caenorhabditis elegans (C. elegans) sample preparation for metabolomics and lipidomics analysis – A review	52
CRISPR biosensing with lateral flow assays for point of care Diagnostics: Overcoming commercial development challenges	51
Recent progress in molecular diagnostics: The synergy of rolling circle amplification and CRISPR/Cas systems (2018–2024) – A concise review	51
Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics	51
Portable sensors in precision agriculture: Assessing advances and challenges in soil nutrient determination	51
Advances in solid-phase microextraction for detecting endocrine disrupting compounds in environmental and biological matrices	51
Synthesis and characterization of TiO2 nanomaterials for sensing environmental volatile compounds (VOCs): A review	50
Recent trends in carbon-based microelectrodes as electrochemical sensors for neurotransmitter detection: A review	50
Advances in 3D printed sensors for food analysis	50
Untargeted chromatographic methods coupled with chemometric strategies for the analysis of food and related samples	50
Modern sorbent-based sample preparation methods for the determination of analytes of forensic interest: A dual-tool approach for evaluation of greenness and practical utility	50
Corrigendum to “Offline preparative separation methods based on electromigration: An overview and current trends” [Trac. Trends Anal. Chem. 170 (2023) 117428]	49
Laser-scribed micro/nanostructures modified surfaces for electrochemical sensors: From fundamentals to applications	49
Uric acid biosensors based on molecular recognition: Classifications, advances, and prospects	49
Editorial Board	49
Exploring advanced materials: Harnessing the synergy of inverse gas chromatography and artificial vision intelligence	49
Editorial Board	49
Variable electric field and atomic percentage of doping on the displacement process of C20 molecules in a nanotube with molecular dynamics simulation	49
Editorial Board	49
Assessing the availability of trace metals including rare earth elements in deep ocean waters of the Clarion Clipperton Zone, NE Pacific: Application of an in situ DGT passive sampling method	49
Recent advances in exhaled breath sample preparation technologies for drug of abuse detection	49
Plasmonic biosensors: Towards fully operative detection platforms for biomedical application and its potential for the diagnosis of autoimmune diseases	48
Forensic drug screening by liquid chromatography hyphenated with high-resolution mass spectrometry (LC-HRMS)	48
Recent advances in post-column derivatization: Enhancing sensitivity and selectivity in liquid chromatography analysis	48
Multi-scenario deployable analysis platform for the detection of illicit pharmaceutical adulteration in dietary supplements	48
Biosensing based on lossy mode resonances	48
Tracking indoor volatile organic compounds with online mass spectrometry	48
Recent advances of cellulose nanofiber-based materials in cell culture: From population to single-cell	48
Thermal shift assay for protein–ligand dissociation constant determination	48
Radiometric strategy to track nanopesticides: An important approach to understand the fate, mechanisms of action and toxicity	48
Polar organic pollutants, micro-nano plastics and nanomaterials: Analytical techniques to reveal the still invisible human physico-chemical exposome	47
Advanced nucleic acid probes for enhanced CRISPR diagnostics	47
Emerging trends in green carbon dots coated with molecularly imprinted polymers for sensor platforms	47
Lights and shadows of mass spectrometry-based metabolomics studies in cancer diagnosis: is there any marker beyond the literature background noise?	47
Cutting-edge MoS2-Based biosensing platforms for detecting contaminants in food samples	47
Ultrasound-assisted microextraction: Advancements, applications, and future directions in analytical chemistry	47
New microextraction techniques in exposome Research: Bridging environmental exposures and human health	47
Recent advances in microfluidic sensors for nutrients detection in water	47
From confinement to quantum tunnelling: Redox cycling electrochemistry across scales for ultra-sensitive molecular sensing	47
Versatile sensing strategies based on emerging programmable prokaryotic Argonautes: From nucleic acid to non-nucleic acid targets	47
Cutting-edge progress in carbon nanomaterial-functionalized silver nanoparticles for enhanced optical and electrochemical sensing applications	46
Challenges and opportunities in the development of planar potentiometric sensors for point-of-care analysis	46
Advances of surface-enhanced Raman spectroscopy in exosomal biomarkers analysis	46
Microfluidic trends in drug screening and drug delivery	46
MOFs/COFs-based hybrids for agricultural sensors: Current state of art and beyond	46
Recent advances in microfluidic single-cell analysis and its applications in drug development	46
Advancements in screening systems for active ingredients in traditional Chinese medicines using ligand fishing technique	45
Deep eutectic solvents-modified advanced functional materials for pollutant detection in food and the environment	45
Staining methodologies for microplastics screening	45
Recent advances in technologies toward the development of 2D materials-based electronic noses	45
Triple-color emission ratiometric fluorescence in biochemical sensing analysis; principles, probe fabrication and applications	45
Fluorescent probes based on bioorthogonal reactions: Construction strategies and applications	45
Plastic problem solved? Environmental implications of synthetic hydrophilic polymers across ecosystem boundaries	45
Advances in nanomaterial-based microfluidic platforms for on-site detection of foodborne bacteria	45
Current materials for miniaturized sample preparation: Recent advances and future trends	45
The review of nanoplastics in plants: Detection, analysis, uptake, migration and risk	45
Advances in the analysis of odorous substances derived from drinking water disinfection	45
Update of high-intensity ultrasound applications for the extraction of pectin from agri-food by-products	45
Artificial intelligence for method development in liquid chromatography	44
Recent progress of gas sensors based on metal oxide composites derived from bimetallic metal-organic frameworks	44
Deep learning for near-infrared spectral data modelling: Hypes and benefits	44
Micro/nanofluidic-electrochemical biosensors for in situ tumor cell analysis	44
State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants	44
Recent advances and applications of Bi2S3-based composites in photoelectrochemical sensors and biosensors	44
Recent advances in responsive lanthanide-doped luminescence nanoprobes in the near-infrared-II window	44
Updated overview of QuEChERS applications in food, environmental and biological analysis (2020–2023)	44
Harnessing non-noble metal-doped carbon composites for remediation of phthalate esters contaminated water systems	43
Contribution of supercritical fluid chromatography to serially coupling columns for chiral and achiral separations	43
Seeing the invisible: Preparative strategies to visualise elusive molecules using mass spectrometry imaging	43
Microextraction techniques as versatile platforms for sample preparation of disinfection byproducts from aqueous media: Advances and challenges	43
Molecularly imprinted polymers towards disease diagnostics	43
Recent advances of upconversion nanoparticles-based lateral flow assays for point-of-care testing	43
Human exposure to micro(nano)plastics: Health risks and analysis methods	43
DNAzyme biosensor as an emerging food safety indicator: History and fundamental mechanism to future prospects	43
Gold nanoparticles conjugated with fluorophore-labeled DNA: Overview of sensing and imaging applications	43
Nanomaterial-based microfluidic systems for cancer biomarker detection: Recent applications and future perspectives	43