Trends in Biotechnology

Papers
(The median citation count of Trends in Biotechnology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Auricular repair: symphony between scaffolds and stem cells270
Subscription and Copyright information262
Electronic plants: the future of agriculture and urban ecosystems?182
Advisory Board and Contents157
Phytohormones: novel strategy for removing emerging contaminants and recovering resources151
Prime editing: advances and therapeutic applications136
Smart materials: rational design in biosystems via artificial intelligence133
Smart Nucleic Acids as Future Therapeutics130
Unlocking the potential of stem-cell-derived ‘synthetic’ embryo models126
Vector-free intra-airway in vivo epigenetic editing124
Manipulating immune activity of macrophages: a materials and mechanics perspective118
Engineering biology approaches to modulate bacterial biofilms109
The green revolution of food waste upcycling to produce polyhydroxyalkanoates105
Bridging the path to multiplexed molecular diagnostics100
Analyzing and understanding the robustness of bioprocesses99
Microalgae: a revolution for salt-affected soil remediation97
Scalable tissue biofabrication via perfusable hollow fiber arrays for cultured meat applications95
Healing wounds with plasma-activated hydrogel therapy93
(R)evolution-on-a-chip92
SynMADE: synthetic microbiota across diverse ecosystems91
Vibrio natriegens as a host for rapid biotechnology89
Food Waste: A Promising Source of Sustainable Biohydrogen Fuel88
Enzyme discovery and engineering for sustainable plastic recycling83
Advisory Board and Contents80
Subscription and Copyright information77
Subscription and Copyright information74
Emerging strategies to develop novel genetically encoded biosensors74
Subscription and Copyright information74
Advisory Board and Contents72
Nanobotic microbiomes against emerging vascular pathogens in agriculture72
Mini-bones: miniaturized bone in vitro models71
UFSC Biotech Network: a transdisciplinary platform for biotechnology innovation in Brazil71
Efficient genome-editing tools to engineer the recalcitrant non-model industrial microorganism Zymomonas mobilis70
Multiscale models quantifying yeast physiology: towards a whole-cell model70
Ocular RNA nanomedicine: engineered delivery nanoplatforms in treating eye diseases69
Printhead on a chip: empowering droplet-based bioprinting with microfluidics68
The GPS for drug development: navigating with evidence from human populations68
Integrating bicarbonate-based microalgal production with alkaline sewage for ocean negative carbon emissions65
Molecular design of microalgae as sustainable cell factories65
Manufacturing innovation to drive down cell therapy costs64
A high-performance protein preparation approach in a single column-free step63
Extended human lymph node explants for evaluation of adaptive immunity63
Next-generation digital biomarkers: continuous molecular health monitoring using wearable devices63
Translational organoid technology – the convergence of chemical, mechanical, and computational biology63
Machine learning in bioprocess development: from promise to practice62
Beyond waste: understanding urine’s potential in precision medicine61
Engineering the mangrove soil microbiome for selection of polyethylene terephthalate-transforming bacterial consortia61
Towards biomanufacturing of cultured meat60
Machine learning to predict de novo protein–protein interactions60
Can protein expression be ‘solved’?58
Metabolic and immunomodulatory control of type 2 diabetes via generating cellular itaconate reservoirs by inflammatory-targeting gene-therapy nanovesicles57
Advisory Board and Contents57
The morally disruptive future of reprogenetic enhancement technologies56
Next-generation 3D-printed nutritious food derived from waste plastic and biomass56
Improving awareness, understanding, and enforcement of responsibilities and regulations in Blue Biotechnology55
Multienzymatic synthesis of nylon monomers from vegetable oils55
Subscription and Copyright information55
A new chapter for anti-idiotypes in low molecular weight compound immunoassays54
Dynamic plasmid copy number control for synthetic biology54
Sebum analysis as an advantageous source of biomolecular information53
3D extrusion bioprinting: rational bioink design and advanced fabrication techniques53
The LEGO® brick road to open science and biotechnology52
Building biomaterials through genetic code expansion51
Advisory Board and Contents50
Advisory Board and Contents50
Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy48
Engineered bacterial therapeutics with material solutions48
Harnessing Streptomyces–plant interactions for agricultural natural product discovery48
Frog ‘N’ Roll: novel synthetic peptides selective against Gram-negative pathogens47
Small but mighty: emerging roles of uORFs in plants46
3D printing of heart valves46
Dynamically regulating metabolic fluxes with synthetic metabolons45
Emerging supramolecular and living materials in oral medicine45
Synthetic biology for plant genetic engineering and molecular farming44
Estimating environmental impacts of early-stage bioprocesses44
Bioprinted, spatially defined breast tumor microenvironment models of intratumoral heterogeneity and drug resistance44
Using synthetic biology to express nitrogenase biosynthesis pathway in rice and to overcome barriers of nitrogenase instability in plant cytosol43
Ethical challenges with 3D bioprinted tissues and organs43
Biosafety and biosecurity: treading China’s synbio tightrope43
Spatial omics for accelerating plant research and crop improvement43
Trends in sustainable single-cell protein from non-grain feedstocks42
Academic entrepreneurship: promise and perils42
Non-sterile cultivation of oleaginous organisms42
From academia to real-life biotech: ‘It takes a village’42
Design principles for engineering light-controlled antibodies41
Rapid selection of transgenic mammalian cells via diphtheria toxin resistance41
Protein–glycan engineering in vaccine design: merging immune mechanisms with biotechnological innovation41
Biotechnological approaches for producing natural pigments in yeasts40
Rethinking techno-moral disruption in bioethics, society, and justice40
Bringing the next biotechnologies to life40
Next-generation industrial biotechnology for low-cost mass production of PHA39
Advanced strategies for enzyme–electrode interfacing in bioelectrocatalytic systems39
Advances in induced anhydrobiosis for cell and gamete storage38
Molecular engineering of insulin for recombinant expression in yeast38
Bioengineering human placentas: social implications of an advancing field37
Microbial electrosynthesis: opportunities for microbial pure cultures37
Harnessing lactic acid bacteria in synthetic microbial consortia37
Advisory Board and Contents37
Long-offset paired nicking-based efficient and precise strategy for in vivo targeted insertion36
Nanobodies: a new frontier in plant disease management36
Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials36
Subscription and Copyright information36
Robots with a human touch36
Merging automation and fundamental discovery into the design–build–test–learn cycle of nontraditional microbes36
Making cow-free caseins and casein micelles36
Bioprocessing technology of muscle stem cells: implications for cultured meat36
HHV-6 and HHV-7 reactivation in allogeneic CAR-T cell therapy35
Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration35
Engineered RNA nanostructures for scalable and efficient RNAi-based pesticides35
Marine-derived bioactive materials as antibiofilm and antivirulence agents35
Advisory Board and Contents35
Computationally guided genome rewiring of Escherichia coli and its application for nanopolyethylene terephthalate (PET) biodegradation and upcycling35
How transdisciplinarity can help biotech-driven biodiversity research35
Efficient and sustained photosynthetic hydrogen production by algae under high light intensity35
Organ-on-a-chip systems for modeling tumor and normal tissue microenvironments in radiotherapy research34
Biotechnology applications of proteins functionalized with DNA oligonucleotides34
Harnessing synthetic biology to develop novel psychedelic therapies34
Welfare impacts of China's regulatory change toward genome-edited crops34
Distillation for in situ recovery of volatile fermentation products33
Apart, Together: Reflections on the COVID-19 Pandemic33
Engineering Minds? Ethical Considerations on Biotechnological Approaches to Mental Health, Well-Being, and Human Flourishing33
Product-driven high-throughput screening of industrial filamentous actinomycetes33
Exploring standards for multicellular mammalian synthetic biology33
Virus-like particles as modular interfaces for biomaterial functionalization32
CRISPR/Cas-based personal glucose meters for nucleic acid detection31
Transforming undergraduate laboratory courses with interlinked real-world challenges31
Engineering M13 phages: surface and morphological strategies for programmable applications31
CRISPR-Cas12c: a noncleaving DNA binder with minimal PAM requirement30
Enzyme Catalyst Engineering toward the Integration of Biocatalysis and Chemocatalysis30
Novel delivery systems for controlled release of bacterial therapeutics30
Light-induced programmable solid–liquid phase transition of biomolecular condensates for improved biosynthesis29
pHNRhCas9NG, single expression cassette-based dual-component dual-transcription unit CRISPR/Cas9 system for plant genome editing29
From Innovation to Application: Bridging the Valley of Death in Industrial Biotechnology29
OMEGA-guided DNA polymerases enable random mutagenesis in a tunable window28
Advancing plant gene activation with CRISPR-Act3.028
Ethical and legal considerations of digital animal models: pioneering reduction and replacement28
Gas plasma technology mediates deep tissue and anticancer events independently of hydrogen peroxide28
An epigenetic regulator synergizes with alphavirus-mediated gene therapy via biomimetic delivery for enhanced cancer therapy28
Synthetic transcription factor engineering for cell and gene therapy27
Oxygen-Releasing Biomaterials: Current Challenges and Future Applications27
RNA and nanocarriers: next generation drug and delivery platform take center stage27
Evading and overcoming AAV neutralization in gene therapy27
Semi-automated biofoundry workflows for sequence coevolution-guided isoprene synthase engineering27
Prime editor integrase systems boost targeted DNA insertion and beyond27
Functionalization of Cellular Membranes with DNA Nanotechnology27
Staying productive under pressure: systems evaluations of β-carotene production in Yarrowia lipolytica under continuous fermentation26
Rational bioengineering of polysaccharide in designing of microbiome modulation26
Dynamic anaerobic digestion-based biorefineries for on-demand renewable energy and bioproducts in a circular bioeconomy26
Immunostimulation in experimental gas plasma therapy for breast cancer26
Rewiring holobiont systems with synthetic biology26
Chips, guts, and gas: unraveling volatile microbial mysteries in real time!26
Harnessing the microbial world for human benefit26
Subscription and Copyright information25
Systematic development of a highly efficient cell factory for 5-aminolevulinic acid production25
Next-generation electroactive biomaterials-integrated bioelectronics for advanced healthcare management25
Application of bacterial extracellular vesicles in gastrointestinal diseases25
Editing a healthier future in plants25
Phase-separated biomolecular condensates for biocatalysis25
Emerging Applications of 3D Printing in Biomanufacturing25
Framing synthetic biology as an innovation-driven market24
Comparison of CRISPR/Cas and Argonaute for nucleic acid tests24
Human bone marrow organoids: emerging progress but persisting challenges24
Advancements and regulations of biomanufacturing cell-based cartilage repair therapies24
Robustness: linking strain design to viable bioprocesses24
Chimeric antigen receptor therapy meets mRNA technology24
Subscription and Copyright information24
The biotechnology revolution in textile dyeing24
Yeast-based screening platforms to understand and improve human health24
Artificial intelligence in biomaterials: a call for unified biocompatibility standards23
The lignocellulosic biorefinery concept is sound: a commentary on Zhao et al.23
Intervertebral disc-on-a-chip: a precision engineered toolbox for low back pain studies23
Blockchain as a frontier in biotechnology and bioenergy applications23
Bioinspired thermoreversible bioink orchestrates focal adhesion-dependent osteogenesis23
Power-to-vitamins: producing folate (vitamin B9) from renewable electric power and CO2 with a microbial protein system23
Advisory Board and Contents23
Escherichia coli selection strains for growth-coupled metabolic engineering23
Programmable embedded bioprinting for one-step manufacturing of arterial models with customized contractile and metabolic functions22
Sensors in blockchain22
Advancing wheat breeding using rye: a key contribution to wheat breeding history22
Strengthening the competitiveness of EU in vitro biotechnologies22
Shaping the future US bioeconomy through safety, security, sustainability, and social responsibility22
Bringing carbon to life via one-carbon metabolism22
Hydrogen production in microbial electrolysis cells with biocathodes22
Large language model for knowledge synthesis and AI-enhanced biomanufacturing22
Nondestructive testing of native and tissue-engineered medical products: adding numbers to pictures22
Prokaryotic Argonautes for in vivo biotechnology and molecular diagnostics22
Engineering chimeric signaling proteins for microbial whole-cell biosensors: from design to deployment22
Osmotic-controlled release oral tablets: technology and functional insights21
Media representations of synthetic biology in China21
Insights on cisgenic plants with durable disease resistance under the European Green Deal21
Subscription and Copyright information21
Pollutant degradation in saline wastewater using synthetic biology21
Chairside live biotherapeutic hydrogel for comprehensive periodontitis therapy21
Cellular reprogramming and the rise of rejuvenation biotech21
Synthetic biology for Taxol biosynthesis and sustainable production21
Navigating microalgae under dynamic CO2 for waste-to-energy conversion21
Large-scale manufacturing of human gallbladder epithelial cell products and derived hepatocytes via a chemically defined approach20
A forward-thinking biocompatibility assessment: drafting future considerations now20
One-pot diagnostic methods based on CRISPR/Cas and Argonaute nucleases: strategies and perspectives20
Efficiency and process development for microbial biomass production using oxic bioelectrosynthesis20
Towards machine learning for hydrogel drug delivery systems20
CarveAdornCurate: a versatile cloud-based platform for constructing multiscale metabolic models19
EccDNA in plant-stress and biotechnological solutions in agriculture19
Microbial cellulose production using ocean water: sustainable and cost-effective?19
Harnessing microbes to pioneer environmental biophotoelectrochemistry19
Subscription and Copyright information19
Validation Is Not Verification: Precise Terminology and Scientific Methods in Bioprocess Modeling19
TRYing to evaluate production costs in microbial biotechnology19
Organs-on-chips: a decade of innovation19
Spatial -omics technologies: the new enterprise in 3D breast cancer models19
Subscription and Copyright information19
Point-of-care detection devices for wound care and monitoring19
Engineering next-generation oxygen-generating scaffolds to enhance bone regeneration19
Robotic micromotors transforming oral drug administration19
Protein–nucleic acid thermodynamic databases for specific uses18
A pathway to improve seaweed aquaculture through microbiota manipulation18
Driving towards digital biomanufacturing by CHO genome-scale models18
Quality by Design for enabling RNA platform production processes18
Gene drive in species complexes: defining target organisms18
Innovation trends in industrial biotechnology18
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection18
Advances in ultrahigh-throughput screening technologies for protein evolution18
Agricultural biotechnology for sustainable food security18
Design of biomass-based renewable materials for environmental remediation18
Biosensors for healthcare: current and future perspectives18
Untethered: using remote magnetic fields for regenerative medicine18
Personalized, connected health enabled by AI and home-based diagnostics17
Ethics and engagement: steering China’s synbio future17
Microscopy imaging of living cells in metabolic engineering17
Advisory Board and Contents17
Advances in biomimetic carbonic anhydrase strategies for CO2 capture17
Subscription and Copyright information17
Comment on ‘Thermodynamic database supports deciphering protein–nucleic acid interactions’17
Challenges in realizing therapeutic antibody biosensing17
Molecular farming for the food sector16
Scientific and public imaginations of xenobiology16
Creating novel metabolic pathways by protein engineering for bioproduction16
In vitro human cell-based models: What can they do and what are their limitations?16
Engineering bacteria for production of sustainable polycyclopropanated jet fuel alternatives15
Meta-adaptive biomaterials: multiscale, spatiotemporal organization and actuation in engineered tissues15
Subscription and Copyright information15
Metabolic engineering for sustainability and health15
Tapping the potential of Gram-positive bacteria for bioelectrochemical applications15
Improving plant C-to-G base editors with a cold-adapted glycosylase and TadA-8e variants15
Advisory Board and Contents15
Thermodynamic database supports deciphering protein–nucleic acid interactions15
CRISPR-based systems for sensitive and rapid on-site COVID-19 diagnostics15
Are integrated bioelectrochemical technologies feasible for wastewater management?15
Highly efficient prime editors for mammalian genome editing based on porcine retrovirus reverse transcriptase15
Intellectual property and funding: fueling Chinese synbio14
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